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Search of human proteins with 71725345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71725345 complexin 3 [Homo sapiens]
(158 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71725345 complexin 3 [Homo sapiens] 311 2e-85
gi|31795561 complexin 4 [Homo sapiens] 194 3e-50
gi|56550065 complexin 2 [Homo sapiens] 62 3e-10
gi|5729783 complexin 2 [Homo sapiens] 62 3e-10
gi|5729781 complexin 1 [Homo sapiens] 59 1e-09
gi|116812573 CWC15 homolog [Homo sapiens] 40 8e-04
gi|120587019 zinc finger protein 318 [Homo sapiens] 38 0.004
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.007
gi|24415404 MDN1, midasin homolog [Homo sapiens] 37 0.007
gi|154354979 myosin X [Homo sapiens] 37 0.009
gi|24234699 keratin 19 [Homo sapiens] 36 0.012
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 36 0.016
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 35 0.027
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 35 0.035
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 35 0.035
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 34 0.045
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 34 0.045
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 34 0.045
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 34 0.045
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 34 0.059
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 34 0.059
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 34 0.059
gi|34878777 ring finger protein 20 [Homo sapiens] 33 0.077
gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-l... 33 0.10
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform... 33 0.10
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 33 0.10
gi|148746195 trichohyalin [Homo sapiens] 33 0.10
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 33 0.10
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 33 0.10
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 33 0.10
>gi|71725345 complexin 3 [Homo sapiens]
Length = 158
Score = 311 bits (796), Expect = 2e-85
Identities = 158/158 (100%), Positives = 158/158 (100%)
Query: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60
MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA
Sbjct: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60
Query: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKA 120
QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKA
Sbjct: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKA 120
Query: 121 SVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM 158
SVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM
Sbjct: 121 SVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM 158
>gi|31795561 complexin 4 [Homo sapiens]
Length = 160
Score = 194 bits (492), Expect = 3e-50
Identities = 98/160 (61%), Positives = 128/160 (80%), Gaps = 2/160 (1%)
Query: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKS-AAEAQGMSREEYEEYQKQLVEEKMERD 59
MAF++K+M+ Q+KNL G E+K +G S A AQGM+REEYEEYQKQ++EEKMERD
Sbjct: 1 MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERD 60
Query: 60 AQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
A FTQ+KAERA LR H R+KYRLPK+E DE+QIQMAG DV+LP +L KM++ED EEEE+K
Sbjct: 61 AAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVDLPEDLRKMVDEDQEEEEDK 120
Query: 120 ASVLGQLASLPGLNLGSLKDKAQATLGDLKQSAE-KCHVM 158
S+LGQ+ +L ++L ++K+KAQAT ++KQ+AE KC VM
Sbjct: 121 DSILGQIQNLQNMDLDTIKEKAQATFTEIKQTAEQKCSVM 160
>gi|56550065 complexin 2 [Homo sapiens]
Length = 134
Score = 61.6 bits (148), Expect = 3e-10
Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 15/136 (11%)
Query: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60
M F++K +GG K++ G + GGE++ D D E EE Q+ L +++ ER A
Sbjct: 1 MDFVMKQALGGATKDM-GKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKA 50
Query: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115
+ + +AER +R RDKY L K E E++ + A G + P++ D EE
Sbjct: 51 KHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110
Query: 116 EEEKASVLGQLASLPG 131
EEE++ + L LPG
Sbjct: 111 EEEESILDTVLKYLPG 126
>gi|5729783 complexin 2 [Homo sapiens]
Length = 134
Score = 61.6 bits (148), Expect = 3e-10
Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 15/136 (11%)
Query: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60
M F++K +GG K++ G + GGE++ D D E EE Q+ L +++ ER A
Sbjct: 1 MDFVMKQALGGATKDM-GKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKA 50
Query: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115
+ + +AER +R RDKY L K E E++ + A G + P++ D EE
Sbjct: 51 KHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110
Query: 116 EEEKASVLGQLASLPG 131
EEE++ + L LPG
Sbjct: 111 EEEESILDTVLKYLPG 126
>gi|5729781 complexin 1 [Homo sapiens]
Length = 134
Score = 59.3 bits (142), Expect = 1e-09
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 15/136 (11%)
Query: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60
M F++K +GG K++ LGG E+K D AA+ + EE Q+ L + + ER A
Sbjct: 1 MEFVMKQALGGATKDMGKMLGGDEEK---DPDAAKKE-------EERQEALRQAEEERKA 50
Query: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115
++ + +AER +R RDKY + K E E++ Q A G + P++ D E
Sbjct: 51 KYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVE 110
Query: 116 EEEKASVLGQLASLPG 131
EE+++ + + LPG
Sbjct: 111 EEDESILDTVIKYLPG 126
>gi|116812573 CWC15 homolog [Homo sapiens]
Length = 229
Score = 40.0 bits (92), Expect = 8e-04
Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 22 GGEDKGDGDKSAAEAQGMSRE-------EYEEYQKQLVEEKMERDAQFTQRKAERATLRS 74
GG KG+GD S Q SR+ +Y + + EE RD + + ERA R
Sbjct: 14 GGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAARE 73
Query: 75 HFRDKYRLPKNETDESQI-------QMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLA 127
RD R + T S + Q+ +++ L +ED EEE + LA
Sbjct: 74 KNRD--RPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLA 131
Query: 128 SLPGLNLGSLKDKAQATLGDLKQSAEK 154
L + +++A+ + +Q AE+
Sbjct: 132 ELEKIKKERAEEQARK---EQEQKAEE 155
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 37.7 bits (86), Expect = 0.004
Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 16/128 (12%)
Query: 39 MSREEYEEYQKQLV---EEKMERDAQFTQRKAE--RATL-RSH------FRDKYRLPKNE 86
+S E+ QKQ V EK++ D + Q+K R L R H R K R
Sbjct: 878 ISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGH 937
Query: 87 TDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQATLG 146
D ++++ + +++A++ +E EE E+K S L ++A + G+N + DK+Q +L
Sbjct: 938 KDPLLVEVSRLQDNIMKDIAELRQE-AEEAEKKQSELDKVAQILGIN---IFDKSQKSLS 993
Query: 147 DLKQSAEK 154
D ++ EK
Sbjct: 994 DSREPTEK 1001
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 37.0 bits (84), Expect = 0.007
Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 16/150 (10%)
Query: 4 MVKTMVGGQLKNLTGSLGGGEDKGDGDK---------SAAEAQGMSREEYEEYQKQLVEE 54
+ K + G+L L + ++K DK + EAQ RE+ +++ L
Sbjct: 939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRL 998
Query: 55 KMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTE 114
+ E++A + + +AERA L+S + E +E ++ EL E+A + +E E
Sbjct: 999 QREKEAAWRELEAERAQLQSQL-------QREQEELLARLEAEKEELSEEIAALQQERDE 1051
Query: 115 EEEEKASVLGQLASLPGLNLGSLKDKAQAT 144
S Q SL +L +K T
Sbjct: 1052 GLLLAESEKQQALSLKESEKTALSEKLMGT 1081
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 37.0 bits (84), Expect = 0.007
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 29/162 (17%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRD-- 78
GGG +G+G K ++ G + + +QK ++K + D++ + + A S D
Sbjct: 4677 GGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGK 4736
Query: 79 --KYRLPKNETDESQIQMAGGDV-----ELPRELAKMI----------EEDTEEEEEKAS 121
L + E D+ + GGD+ +L E A + EED EEE+ K
Sbjct: 4737 MHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 4796
Query: 122 VLGQ---------LASLPGLNLG-SLKDKAQATLGDLKQSAE 153
G +A L+ G S KDK+Q + K+ AE
Sbjct: 4797 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAE 4838
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Query: 41 REEYEEYQKQLVEEKMERDAQFTQRKAER--ATLRSHFRDKYRLPKNETDESQIQMAGGD 98
+ E EE +KQ EEK +R+ + +R+ ER A LR+ ++ R + + +Q + +
Sbjct: 815 KREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR---KQQELEALQKSQKE 871
Query: 99 VELPRELAKMIEEDTEEE 116
EL REL K E EE
Sbjct: 872 AELTRELEKQKENKQVEE 889
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 36.2 bits (82), Expect = 0.012
Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
Query: 12 QLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERAT 71
++ L G +GG + + + +Y+ + + + +A FT R E
Sbjct: 221 EISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNR 280
Query: 72 LRSHFRDKYRLPKNETDESQIQMAGGDVELPRELA-KMIEEDTEEEEEKASVLGQLASLP 130
+ ++ ++ ++E + + + G ++EL +L+ K EDT E E A QLA +
Sbjct: 281 EVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETE-ARFGAQLAHIQ 339
Query: 131 GLNLGSLKDKAQATLGDLKQSAEK 154
L G +A LGD++ +E+
Sbjct: 340 ALISG-----IEAQLGDVRADSER 358
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 35.8 bits (81), Expect = 0.016
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 17/104 (16%)
Query: 39 MSREEYEEYQKQLVEEKME------------RDAQFTQRKAERATLRSHFRDKYRLPKNE 86
M +E++E KQL E E R Q QRK + A + K L +N+
Sbjct: 1445 MQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISR----KEALKENK 1500
Query: 87 TDESQIQMAGGDVE-LPRELAKMIEEDTEEEEEKASVLGQLASL 129
+ + ++ +A G +E L + LA + + + + +EK +VLG+LA L
Sbjct: 1501 SLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1544
Score = 28.1 bits (61), Expect = 3.3
Identities = 35/150 (23%), Positives = 72/150 (48%), Gaps = 18/150 (12%)
Query: 12 QLKNLTGSLGGG-EDKGDG----DKSAAEAQGMSR--EEYEEYQKQLVEEKMERDAQFTQ 64
QL L GS+G +D D + +E + + + E EE ++QLV+EK + +++ +
Sbjct: 1929 QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1988
Query: 65 RKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLG 124
E+ + + P N++ ++Q ++ ++ K +++D +EK S L
Sbjct: 1989 EYLEK------IQGAQKEPGNKSHAKELQEL---LKEKQQEVKQLQKDCIRYQEKISALE 2039
Query: 125 Q-LASLPGLNLGSLKDKAQATLGDLKQSAE 153
+ + +L + S KD + T +L Q+ E
Sbjct: 2040 RTVKALEFVQTESQKD-LEITKENLAQAVE 2068
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 35.0 bits (79), Expect = 0.027
Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 28 DGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNET 87
D K E +G +E +E +K+ E + ER+ + +R+ ER R R+K + + E
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 88 DESQIQMAGGDVELPRELAKMIEEDTEEEEEKAS 121
+ + + D R+ + E D + + E++S
Sbjct: 346 ERDRDR----DRTKERDRDRDRERDRDRDRERSS 375
Score = 30.4 bits (67), Expect = 0.66
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 7/100 (7%)
Query: 24 EDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQ---FTQRKAERATLRSHFRDKY 80
E+KG +K E + RE E +++ + ER+ + +++ ER R RD+
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352
Query: 81 RLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKA 120
R + + D + + D + RE + +D EK+
Sbjct: 353 RTKERDRDRDRER----DRDRDRERSSDRNKDRSRSREKS 388
Score = 28.1 bits (61), Expect = 3.3
Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 7/96 (7%)
Query: 24 EDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLP 83
E D +K + ++ SR+ E +++ E+ + +R+ ER R R+K +
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Query: 84 KNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
E DE D R+L + + E +E+
Sbjct: 432 DREEDEE-------DAYERRKLERKLREKEAAYQER 460
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 34.7 bits (78), Expect = 0.035
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 11 GQLKNLTGSLGGGEDKGDG--DKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAE 68
G+ K++ + G E +GDG ++ ++ A+ EE E+ +K +MER + + AE
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 69 RATLR----SHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+ + K R ++ + +Q GG+ E + E D EEEEEK
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE--HGEGEEEEGDREEEEEK 751
Score = 32.3 bits (72), Expect = 0.17
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 11/110 (10%)
Query: 21 GGGEDKGDGDKSAA------EAQGMSREEYEEYQKQLVEEKMERDAQFTQR-----KAER 69
GG E+ G+G++ E +G +EE E + + EK E + + +R K E
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 70 ATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+ ++ + E E ++ GG+VE + + EE+ E EEE+
Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Score = 32.0 bits (71), Expect = 0.23
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKY 80
G GE++G+G+ E +G EE EE + + EE+ E + + + + E ++
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 81 RLPKNETD-ESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+ E + E + + G+ E + EE+ EEE E+
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Score = 30.8 bits (68), Expect = 0.50
Identities = 24/111 (21%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQ------RKAERATLRS 74
G GE++G+G+ E +G E E +++ EE+ E + + + + E +
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 75 HFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQ 125
+ + E +E + + + E E + E+ EEEE K G+
Sbjct: 1024 EVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074
Score = 30.0 bits (66), Expect = 0.86
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKY 80
G G+++G+G++ E + E +E ++ EEK E + + + E R +++
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKE-ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE- 810
Query: 81 RLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
E + +++ G+ E E + EE+ E EEE+
Sbjct: 811 ---GGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Score = 28.1 bits (61), Expect = 3.3
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYE-EYQKQLVEEKMERDAQFTQRKAERATLRSHFRDK 79
G GE++G+G+ E +G EE E E +++ E K E + + + + E D
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 80 YRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+ E E + + G+ E E EE E EE+
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Score = 27.3 bits (59), Expect = 5.6
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 3/43 (6%)
Query: 18 GSLGGGEDKGDGDKSAAEAQGMSRE---EYEEYQKQLVEEKME 57
G + G E +G+G++ E +G RE E EE ++ EE+ E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1065
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 34.7 bits (78), Expect = 0.035
Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 14/131 (10%)
Query: 23 GEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRL 82
G + + +++A EA+G ++ E E + Q EE+ + +++ +
Sbjct: 1937 GAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV------------ 1984
Query: 83 PKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQ 142
+ + E + Q DVE P +M E + E + E V Q S G ++ + Q
Sbjct: 1985 -ETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS-EGEEAQEVEGETQ 2042
Query: 143 ATLGDLKQSAE 153
T GD + ++
Sbjct: 2043 KTEGDAQPESD 2053
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 34.3 bits (77), Expect = 0.045
Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 15/112 (13%)
Query: 34 AEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQ 93
AE Q + E +E Q +L EE+ R+ + +RKAE R K L S +
Sbjct: 135 AEQQRIRNEREKERQNRLAEERARREEEENRRKAE-----DEARKKKAL-------SNMM 182
Query: 94 MAGGDVELPRELAKMIEEDTEEEEEKASVLGQ---LASLPGLNLGSLKDKAQ 142
GG ++ + + + E E+K +L + + ++ LN L++KA+
Sbjct: 183 HFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 234
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 34.3 bits (77), Expect = 0.045
Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 31 KSAAEAQGMSREEYE---EYQKQLVEEKMERDAQFTQRKAERATLRSHFRD--------K 79
+ + QG +EY+ +Y KQ E+ E Q T ++A+ + + + K
Sbjct: 54 RQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLK 113
Query: 80 YRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKD 139
RL + E + S+I +++ K +E+D E EEK + Q L L
Sbjct: 114 NRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTD---EQLNDLYH 170
Query: 140 KAQATLGDLKQSAEKCH 156
Q T+ + ++ CH
Sbjct: 171 NHQRTVREKERKLVDCH 187
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 34.3 bits (77), Expect = 0.045
Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 31 KSAAEAQGMSREEYE---EYQKQLVEEKMERDAQFTQRKAERATLRSHFRD--------K 79
+ + QG +EY+ +Y KQ E+ E Q T ++A+ + + + K
Sbjct: 193 RQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLK 252
Query: 80 YRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKD 139
RL + E + S+I +++ K +E+D E EEK + Q L L
Sbjct: 253 NRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTD---EQLNDLYH 309
Query: 140 KAQATLGDLKQSAEKCH 156
Q T+ + ++ CH
Sbjct: 310 NHQRTVREKERKLVDCH 326
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 34.3 bits (77), Expect = 0.045
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 22/122 (18%)
Query: 41 REEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVE 100
RE E +++ E + ERD + +R+ ER R H RDK R + E E
Sbjct: 406 RERERENRQRERERERERDRERERRQREREREREHERDKERQRRKE-------------E 452
Query: 101 LPRELAKMIEED---------TEEEEEKASVLGQLASLPGLNLGSLKDKAQATLGDLKQS 151
RE AK E+D E E+EK + P K +A T +K++
Sbjct: 453 WERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
Query: 152 AE 153
E
Sbjct: 513 DE 514
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 33.9 bits (76), Expect = 0.059
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 34 AEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQ 93
AE Q + E +E Q +L EE+ R+ + +RKAE R K L S +
Sbjct: 130 AEQQRIRNEREKERQNRLAEERARREEEENRRKAE-----DEARKKKAL-------SNMM 177
Query: 94 MAGGDVELPRELAKMIEEDTEEEEEKASVL--GQLASLPGLNLGSLKDKAQ 142
GG ++ + K + TE E++K + ++ ++ LN L++KA+
Sbjct: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 228
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 33.9 bits (76), Expect = 0.059
Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 11 GQLKNLTGSLGGGED--KGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAE 68
G + GS G ED K G+ S ++++ EE ++ EE+++ A+ +E
Sbjct: 34 GDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSE 93
Query: 69 RATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLAS 128
+ ++ K E + + + E +E K E++ E+E+EKA+V +A+
Sbjct: 94 KQLIKME-------KKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAA 146
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 33.9 bits (76), Expect = 0.059
Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 11 GQLKNLTGSLGGGED--KGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAE 68
G + GS G ED K G+ S ++++ EE ++ EE+++ A+ +E
Sbjct: 34 GDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSE 93
Query: 69 RATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLAS 128
+ ++ K E + + + E +E K E++ E+E+EKA+V +A+
Sbjct: 94 KQLIKME-------KKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAA 146
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 33.5 bits (75), Expect = 0.077
Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 16/135 (11%)
Query: 32 SAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRD----KYRLPKNET 87
S + A S+E+ E + + EE+ ER+ + +R+ ER + R+ K + + E
Sbjct: 545 SQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKER 604
Query: 88 DESQIQMAG-------GDVELPRELAKMIEEDTEEEEEKASVLGQLASLP-----GLNLG 135
D ++ + G + E+ ++L +++ E ++E +L S P + L
Sbjct: 605 DSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLM 664
Query: 136 SLKDKAQATLGDLKQ 150
+ + K++A L DL+Q
Sbjct: 665 AAEKKSKAELEDLRQ 679
Score = 27.3 bits (59), Expect = 5.6
Identities = 27/137 (19%), Positives = 56/137 (40%), Gaps = 17/137 (12%)
Query: 24 EDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLP 83
E+K D+ A E+ E QK+L K E +A ++ RL
Sbjct: 691 ENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLM 750
Query: 84 K--NETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKA 141
+ E D++ ++ ++ ++ K+++E+ EE ++ +LK +
Sbjct: 751 QQLREKDDANFKLMSERIK-SNQIHKLLKEEKEELADQVL--------------TLKTQV 795
Query: 142 QATLGDLKQSAEKCHVM 158
A L +++ EK H++
Sbjct: 796 DAQLQVVRKLEEKEHLL 812
>gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 547
Score = 33.1 bits (74), Expect = 0.10
Identities = 25/102 (24%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 46 EYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPREL 105
E QK+ + E+ ER + +R + A ++ F++ N ++S +Q+ EL +L
Sbjct: 350 EGQKERLREQQERLPEQEERLQQLAEPQNSFKEL-----NNENKSVLQLEQQVKELQEKL 404
Query: 106 AKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQATLGD 147
K E +++++ + L +LPG G +D+A D
Sbjct: 405 GKERLEAASQQKQQLTAQLSLMALPGEAQGGDEDEAAGAAAD 446
>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
[Homo sapiens]
Length = 807
Score = 33.1 bits (74), Expect = 0.10
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 30 DKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRK------AERATLRSHFRDKYRLP 83
DK A E + + +E+ ++ Q+Q ++K +RD + +RK E L +
Sbjct: 49 DKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPT 108
Query: 84 KNETDE--SQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+E DE + G + A +I++ +EEEEE+
Sbjct: 109 SDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEE 146
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 33.1 bits (74), Expect = 0.10
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 30 DKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRK------AERATLRSHFRDKYRLP 83
DK A E + + +E+ ++ Q+Q ++K +RD + +RK E L +
Sbjct: 49 DKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPT 108
Query: 84 KNETDE--SQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
+E DE + G + A +I++ +EEEEE+
Sbjct: 109 SDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEE 146
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 33.1 bits (74), Expect = 0.10
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
Query: 31 KSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNET--- 87
K E Q + R+E + ++Q + K + Q Q + E+ R K+RL + +
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 88 --------DESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
DE Q++ G +L +E + ED + +E+
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Score = 29.6 bits (65), Expect = 1.1
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 37 QGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAG 96
Q + RE+ E +++L E++ER Q +R+ + +L K+E E + Q
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ-- 645
Query: 97 GDVELPRELAKMIEEDTEEEEEK 119
+L RE + E+ + EEE+
Sbjct: 646 ---QLRREQQERREQRLKREEEE 665
Score = 28.9 bits (63), Expect = 1.9
Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Query: 24 EDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLP 83
E+K + + A+ RE+ E + EE+ +R+ +F + E+ R R++ +
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLR--AEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 84 KNETDESQIQMAGGDVELPRELAKMIEEDTEEEEE 118
+ +E Q+Q RE A+ ++E+ + +E
Sbjct: 832 QFLEEEEQLQR--------RERAQQLQEEEDGLQE 858
Score = 28.1 bits (61), Expect = 3.3
Identities = 22/98 (22%), Positives = 45/98 (45%)
Query: 20 LGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDK 79
L GE++ + + + R+E Q+Q +E+ ER A+ Q ++ + F D+
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 80 YRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEE 117
+L + E E + + + RE + ++ EE+E
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Score = 26.6 bits (57), Expect = 9.5
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 37 QGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAG 96
Q + RE+ E EE+ ER Q +R+ ++ + R K E +E + Q
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQ--ERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 97 GDVELPRELAKMIEEDTEEEEEKASVLGQLAS 128
+ +L RE + E+ + +EE+ + +L S
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRS 534
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 33.1 bits (74), Expect = 0.10
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 21 GGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERD 59
GGG D GD ++ E + EE EE Q++ EE+ E +
Sbjct: 851 GGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889
Score = 28.1 bits (61), Expect = 3.3
Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 6/108 (5%)
Query: 17 TGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLV-----EEKMERDAQFTQRKAERAT 71
T GGE + +G+ E QG E +E + + E++ E A+ + K
Sbjct: 769 TEEKSGGETQPEGE-GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGE 827
Query: 72 LRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEK 119
S + + DE ++ GG E + EE+ EEEEE+
Sbjct: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEE 875
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 33.1 bits (74), Expect = 0.10
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 14 KNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLR 73
+++ S+GG +D+ DGD E +G S E EEY+ + E+ + + + + K R +R
Sbjct: 1184 EDVEDSMGGEDDEVDGD----EEEGQSEE--EEYEVEQDEDDSQEEEEVSLPKRGRPQVR 1237
Query: 74 SHFRDKYRLPKNETDESQIQMAG 96
+ + +L + + Q Q G
Sbjct: 1238 LPVKTRGKLSSSFSSRGQQQEPG 1260
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 33.1 bits (74), Expect = 0.10
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 14 KNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERATLR 73
+++ S+GG +D+ DGD E +G S E EEY+ + E+ + + + + K R +R
Sbjct: 1216 EDVEDSMGGEDDEVDGD----EEEGQSEE--EEYEVEQDEDDSQEEEEVSLPKRGRPQVR 1269
Query: 74 SHFRDKYRLPKNETDESQIQMAG 96
+ + +L + + Q Q G
Sbjct: 1270 LPVKTRGKLSSSFSSRGQQQEPG 1292
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,599,586
Number of Sequences: 37866
Number of extensions: 248823
Number of successful extensions: 2424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 1995
Number of HSP's gapped (non-prelim): 609
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.