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Search of human proteins with 71274142
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71274142 HES/HEY-like transcription factor [Homo sapiens] 668 0.0
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i... 82 5e-16
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i... 81 1e-15
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ... 72 5e-13
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho... 67 3e-11
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens] 54 2e-07
gi|5031763 hairy and enhancer of split 1 [Homo sapiens] 52 6e-07
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens] 52 9e-07
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens] 50 3e-06
gi|13540521 basic helix-loop-helix domain containing, class B, 3... 50 4e-06
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens] 49 6e-06
gi|58219048 hairy and enhancer of split 5 [Homo sapiens] 48 1e-05
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens] 46 5e-05
gi|145207994 hairy and enhancer of split 7 [Homo sapiens] 45 9e-05
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens] 43 4e-04
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 40 0.003
gi|226371735 iroquois homeobox 3 [Homo sapiens] 39 0.005
gi|31543417 phospholipid scramblase 3 [Homo sapiens] 39 0.006
gi|23397672 homeobox D4 [Homo sapiens] 39 0.008
gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapi... 38 0.011
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 38 0.011
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 38 0.014
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ... 38 0.014
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ... 38 0.014
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 38 0.014
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 38 0.014
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 37 0.018
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 37 0.024
gi|208431824 forkhead box I3 [Homo sapiens] 37 0.031
gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens] 36 0.041
>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
Length = 327
Score = 668 bits (1724), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MSDKLKERKVSRLSPNGTCALVVEASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHK 60
MSDKLKERKVSRLSPNGTCALVVEASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHK
Sbjct: 1 MSDKLKERKVSRLSPNGTCALVVEASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHK 60
Query: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR
Sbjct: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
Query: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM
Sbjct: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
Query: 181 KNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPE 240
KNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPE
Sbjct: 181 KNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPE 240
Query: 241 FAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGL 300
FAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGL
Sbjct: 241 FAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGL 300
Query: 301 DRHYLNLIGHAHPNALNLHTPQHPPVL 327
DRHYLNLIGHAHPNALNLHTPQHPPVL
Sbjct: 301 DRHYLNLIGHAHPNALNLHTPQHPPVL 327
>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
isoform b [Homo sapiens]
Length = 308
Score = 82.4 bits (202), Expect = 5e-16
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 56/275 (20%)
Query: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
+IEKRRRDRIN L+EL + VP A KQ
Sbjct: 56 IIEKRRRDRINNSLSELRRLVPSAFEKQ-------------------------------- 83
Query: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
++ Q S KLEKAEIL+MTV +L+ LH+A +G A LA +Y G+ EC+
Sbjct: 84 -----VMEQGSAKLEKAEILQMTVDHLKMLHTAG-GKGYFDAHALA--MDYRSLGFRECL 135
Query: 181 KNLVHYLTTVERMETKDTKYARILAFLQSKA--RLGAEPAFPPLGSLP-EPDFSYQLHPA 237
+ YL+ +E ++ D R+++ L + A R A A LG +P F + H A
Sbjct: 136 AEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHHPHIA 195
Query: 238 GPEFA---GHSPGEAAVFP-----QGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQ 289
P GH P QG P P P+ P PV + S ++
Sbjct: 196 HPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPVLPV-VTSASKL 254
Query: 290 HSPFLTPVQGLDRHYLNLIGHAH---PNALNLHTP 321
P L+ V L + G H PNAL+ P
Sbjct: 255 SPPLLSSVASLSAFPFS-FGSFHLLSPNALSPSAP 288
>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
isoform a [Homo sapiens]
Length = 304
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 112/275 (40%), Gaps = 60/275 (21%)
Query: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
+IEKRRRDRIN L+EL + VP A KQG
Sbjct: 56 IIEKRRRDRINNSLSELRRLVPSAFEKQG------------------------------- 84
Query: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
S KLEKAEIL+MTV +L+ LH+A +G A LA +Y G+ EC+
Sbjct: 85 ----------SAKLEKAEILQMTVDHLKMLHTAG-GKGYFDAHALA--MDYRSLGFRECL 131
Query: 181 KNLVHYLTTVERMETKDTKYARILAFLQSKA--RLGAEPAFPPLGSLP-EPDFSYQLHPA 237
+ YL+ +E ++ D R+++ L + A R A A LG +P F + H A
Sbjct: 132 AEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHIPWGTVFGHHPHIA 191
Query: 238 GPEFA---GHSPGEAAVFP-----QGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQ 289
P GH P QG P P P+ P PV + S ++
Sbjct: 192 HPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSLGPVLPV-VTSASKL 250
Query: 290 HSPFLTPVQGLDRHYLNLIGHAH---PNALNLHTP 321
P L+ V L + G H PNAL+ P
Sbjct: 251 SPPLLSSVASLSAFPFS-FGSFHLLSPNALSPSAP 284
>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
Length = 328
Score = 72.4 bits (176), Expect = 5e-13
Identities = 71/230 (30%), Positives = 101/230 (43%), Gaps = 58/230 (25%)
Query: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
+IEKRRRDRIN L+EL + VP A KQG
Sbjct: 50 IIEKRRRDRINSSLSELRRLVPTAFEKQG------------------------------- 78
Query: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
S KLEKAE+L+MTV +L+ LH+ + L +F + G+ EC+
Sbjct: 79 ----------SSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRS---IGFRECL 125
Query: 181 KNLVHYLTTVERMETK-DTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGP 239
++ YL +E ++ D R+L+ L S A EP+ P G L P + +
Sbjct: 126 TEVIRYLGVLEGPSSRADPVRIRLLSHLNSYA-AEMEPSPTPTGPLAFPAWPW------- 177
Query: 240 EFAGHSPGEAAVFPQGSGAGPFPWP--PGAARSPA--LPYLPSAPVPLAS 285
F PG A+ Q + G P P PG + SPA +P L +AP+ A+
Sbjct: 178 SFFHSCPGLPALSNQLAILGRVPSPVLPGVS-SPAYPIPALRTAPLRRAT 226
>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
sapiens]
Length = 337
Score = 66.6 bits (161), Expect = 3e-11
Identities = 49/151 (32%), Positives = 70/151 (46%), Gaps = 44/151 (29%)
Query: 61 VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120
+IEKRRRDRIN L+EL + VP A KQG
Sbjct: 55 IIEKRRRDRINNSLSELRRLVPTAFEKQG------------------------------- 83
Query: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180
S KLEKAEIL+MTV +L+ L A +G A LA ++ G+ EC+
Sbjct: 84 ----------SAKLEKAEILQMTVDHLKML-QATGGKGYFDAHALA--MDFMSIGFRECL 130
Query: 181 KNLVHYLTTVERMETKDTKYARILAFLQSKA 211
+ YL++VE +++ D R+++ L + A
Sbjct: 131 TEVARYLSSVEGLDSSDPLRVRLVSHLSTCA 161
>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
Length = 221
Score = 53.5 bits (127), Expect = 2e-07
Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 74/266 (27%)
Query: 25 ASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHK-----VIEKRRRDRINRCLNELGK 79
A+D+P + PMAG + S + R+ H+ V+EKRRR RIN L +L
Sbjct: 2 AADTPGKPSASPMAGA--PASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKT 59
Query: 80 TVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEI 139
+ AL K+ KLEKA+I
Sbjct: 60 LILDALRKESSRHS---------------------------------------KLEKADI 80
Query: 140 LEMTVQYLRALHSADFPRGREKAELLAEFA--NYFHYGYHECMKNLVHYLTTVERM--ET 195
LEMTV++LR+L R + A L A+ A + G+HEC+ + +L E + +
Sbjct: 81 LEMTVRHLRSLR-----RVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADV 135
Query: 196 KDTKYARILAFLQ----SKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGH------- 244
+ + A L+ S+ PA P PE Y P P G
Sbjct: 136 RSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPE---VYAGRPLLPSLGGPFPLLAPP 192
Query: 245 -SPGEAAVFPQGSGAGP----FPWPP 265
PG P AGP PW P
Sbjct: 193 LLPGLTRALPAAPRAGPQGPGGPWRP 218
>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
Length = 280
Score = 52.4 bits (124), Expect = 6e-07
Identities = 59/213 (27%), Positives = 79/213 (37%), Gaps = 51/213 (23%)
Query: 58 SHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQA 117
S ++EKRRR RIN L++L + AL K
Sbjct: 38 SKPIMEKRRRARINESLSQLKTLILDALKKDSSRHS------------------------ 73
Query: 118 LGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYH 177
KLEKA+ILEMTV++LR L A + G+
Sbjct: 74 ---------------KLEKADILEMTVKHLRNLQRAQMTAALSTD---PSVLGKYRAGFS 115
Query: 178 ECMKNLVHYLTTVERMETK-DTKYARILAFLQSKARLGAEPAFP-PLGSLPEPDFSYQLH 235
ECM + +L+T E + T+ T+ LA ++ P P P P P
Sbjct: 116 ECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPP---PPG 172
Query: 236 PAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAA 268
P GP+ A +P V P GA P PPG A
Sbjct: 173 PGGPQHAPFAPPPPLV-PIPGGAAP---PPGGA 201
>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
Length = 222
Score = 51.6 bits (122), Expect = 9e-07
Identities = 49/173 (28%), Positives = 73/173 (42%), Gaps = 22/173 (12%)
Query: 126 LLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVH 185
LL + KLE AE+LE+TV+ ++ + R RE+ +L AE + F GY +CM +
Sbjct: 51 LLAGAEAKLENAEVLELTVRRVQGVLRG---RAREREQLQAEASERFAAGYIQCMHEVHT 107
Query: 186 YLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAG-- 243
+++T + ++ A + AE L S+P + S G AG
Sbjct: 108 FVSTCQAID----------------ATVAAELLNHLLESMPLREGSSFQDLLGDALAGPP 151
Query: 244 HSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTP 296
+PG + G+ P P PPG L AP S A P L P
Sbjct: 152 RAPGRSGWPAGGAPGSPIPSPPGPG-DDLCSDLEEAPEAELSQAPAEGPDLVP 203
>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
Length = 224
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/249 (25%), Positives = 92/249 (36%), Gaps = 66/249 (26%)
Query: 50 ESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSS 109
E+R ++EK+RR RIN L EL L+L+
Sbjct: 21 ETRGDRKARKPLVEKKRRARINESLQEL--------------------------RLLLAG 54
Query: 110 ATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFA 169
A V KLE AE+LE+TV+ ++ + R RE+ +L AE +
Sbjct: 55 AEV------------------QAKLENAEVLELTVRRVQGVLRG---RAREREQLQAEAS 93
Query: 170 NYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPD 229
F GY +CM + +++T + ++ A + AE L S+P +
Sbjct: 94 ERFAAGYIQCMHEVHTFVSTCQAID----------------ATVAAELLNHLLESMPLRE 137
Query: 230 FSYQLHPAGPEFAG--HSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPA 287
S G AG +PG + G+ P P PPG L AP S A
Sbjct: 138 GSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPG-DDLCSDLEEAPEAELSQA 196
Query: 288 QQHSPFLTP 296
P L P
Sbjct: 197 PAEGPDLVP 205
>gi|13540521 basic helix-loop-helix domain containing, class B, 3
[Homo sapiens]
Length = 482
Score = 49.7 bits (117), Expect = 4e-06
Identities = 50/229 (21%), Positives = 87/229 (37%), Gaps = 68/229 (29%)
Query: 42 PHGTLSVEESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSR 101
P ++ ++++ + H++IEK+RRDRIN C+ +L +P
Sbjct: 32 PKRSMKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLP------------------- 72
Query: 102 VRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREK 161
L L + G LEKA +LE+T+++L+AL + + ++
Sbjct: 73 ----------------------EHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKI 110
Query: 162 AEL----------LAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKA 211
L + + FH G+ C K ++ YL+ E ++ + +++ L + A
Sbjct: 111 IALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLINHLHAVA 170
Query: 212 RLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGP 260
LP P Q P S G A GS A P
Sbjct: 171 ----------TQFLPTPQLLTQQVPL-------SKGTGAPSAAGSAAAP 202
>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
Length = 247
Score = 48.9 bits (115), Expect = 6e-06
Identities = 66/251 (26%), Positives = 90/251 (35%), Gaps = 71/251 (28%)
Query: 35 GPMAGKCPHGTLSVEESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEA 94
G G+ GT V + + PV +EKRRR RIN L +L + AL K+
Sbjct: 45 GATGGREGRGTQPVPDPQSSKPV----MEKRRRARINESLAQLKTLILDALRKESSRHS- 99
Query: 95 LAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSAD 154
KLEKA+ILEMTV++LR+L
Sbjct: 100 --------------------------------------KLEKADILEMTVRHLRSLR--- 118
Query: 155 FPRGREKAELLAEFA--NYFHYGYHECMKNLVHYLTTVERM--ETKDTKYARILAFLQ-- 208
R + A L A+ A + G+HEC+ + +L E + + + + A L+
Sbjct: 119 --RVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 176
Query: 209 --SKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGH--------SPGEAAVFPQGSGA 258
S+ PA P PE Y P P G PG P A
Sbjct: 177 GPSRRPASLSPAAPAEAPAPE---VYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRA 233
Query: 259 GP----FPWPP 265
GP PW P
Sbjct: 234 GPQGPGGPWRP 244
>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
Length = 166
Score = 47.8 bits (112), Expect = 1e-05
Identities = 53/200 (26%), Positives = 76/200 (38%), Gaps = 58/200 (29%)
Query: 49 EESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLS 108
E++R+R PV +EK RRDRIN + +L + A+
Sbjct: 15 EKNRLRKPV----VEKMRRDRINSSIEQLKLLLEQEFARH-------------------- 50
Query: 109 SATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEF 168
Q + KLEKA+ILEM V YL+ HS F L ++
Sbjct: 51 --------------------QPNSKLEKADILEMAVSYLK--HSKAFVAAAGPKSLHQDY 88
Query: 169 ANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPL--GSLP 226
+ GY C++ V +LT +T+ ++L Q A PA P G+ P
Sbjct: 89 SE----GYSWCLQEAVQFLTLHAASDTQ----MKLLYHFQRPPAAPAAPAKEPKAPGAAP 140
Query: 227 EPDFSYQLHPAGPEFAGHSP 246
P S + A A H P
Sbjct: 141 PPALSAKATAAAA--AAHQP 158
>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
Length = 412
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/226 (21%), Positives = 82/226 (36%), Gaps = 57/226 (25%)
Query: 40 KCPHGTLSVEESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIR 99
K G E+S+ + H++IEK+RRDRIN C+ +L +P
Sbjct: 38 KSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLP----------------- 80
Query: 100 SRVRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHS------- 152
L L + G LEKA +LE+T+++++AL +
Sbjct: 81 ------------------------EHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQ 116
Query: 153 ------ADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAF 206
+ G + F G+ C + ++ YL E T+D K ++++
Sbjct: 117 KIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHE--NTRDLKSSQLVTH 174
Query: 207 LQSKARLGAEPAFPPLGSLPEPD-FSYQLHPAGPEFAGHSPGEAAV 251
L + S P P ++ P+ P PG+ V
Sbjct: 175 LHRVVSELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGSEGPGKNCV 220
>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
Length = 225
Score = 45.1 bits (105), Expect = 9e-05
Identities = 66/259 (25%), Positives = 88/259 (33%), Gaps = 74/259 (28%)
Query: 50 ESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSS 109
E+R + ++EKRRRDRINR L EL L R+R ++L
Sbjct: 8 ENRDGPKMLKPLVEKRRRDRINRSLEEL---------------RLLLLERTRDQNL---- 48
Query: 110 ATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPR-GREKAELLAEF 168
+ KLEKAEILE V YLR + P R +
Sbjct: 49 --------------------RNPKLEKAEILEFAVGYLRERSRVEPPGVPRSPVQDAEAL 88
Query: 169 ANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSK-------------ARLGA 215
A+ + G+ EC+ L + + ++ + +L+ K R
Sbjct: 89 ASCYLSGFRECLLRLAAFAHDAS-PAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSL 147
Query: 216 EPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQ-------GSGA-----GPFPW 263
+PA P LG LH P GH A P SGA G P
Sbjct: 148 DPAAPALGP--------ALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPP 199
Query: 264 PPGAARSPALPYLPSAPVP 282
PP R P P P P
Sbjct: 200 PPPPHRQDGAPKAPLPPPP 218
>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
Length = 173
Score = 42.7 bits (99), Expect = 4e-04
Identities = 49/185 (26%), Positives = 75/185 (40%), Gaps = 22/185 (11%)
Query: 89 GEPQEA--LAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLL-----QSSGKLEKAEILE 141
G P+ A A++R ++ L+ Q+L + +G L L + KLEKA++LE
Sbjct: 2 GLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLE 61
Query: 142 MTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYA 201
MTV++L+ L ++ +P + + GY C+ L L +E + A
Sbjct: 62 MTVRFLQELPASSWPTAAPLP------CDSYREGYSACVARLARVLPACRVLEPAVS--A 113
Query: 202 RILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAV-FPQGSGAGP 260
R+L L +A A L D S PA + P A V P GP
Sbjct: 114 RLLEHLWRRA------ASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
Query: 261 FPWPP 265
W P
Sbjct: 168 GLWRP 172
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/87 (36%), Positives = 38/87 (43%), Gaps = 16/87 (18%)
Query: 217 PAFPPLGSLPEPDFSYQLHPAGPE--FAGHSP---------GEAAVFPQGSGAGPFPWPP 265
P P LGS+P P S P GP F H P G P+ GAG P
Sbjct: 1298 PPLPQLGSIPPPPASAP--PVGPHRHFHAHGPVPGPQHYTLGRPGRAPR-RGAGGHPQFA 1354
Query: 266 GAARSPALPYLPSAPVPLASPAQQHSP 292
R P + P++P+PL SPA QH P
Sbjct: 1355 PHGRHPL--HQPTSPLPLYSPAPQHPP 1379
Score = 37.0 bits (84), Expect = 0.024
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 1/102 (0%)
Query: 217 PAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPF-PWPPGAARSPALPY 275
P PP F + HP AG + G + P GS + P P P + SP P+
Sbjct: 1375 PQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPH 1434
Query: 276 LPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALN 317
P+P SP HSP H G A+P + N
Sbjct: 1435 PSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPSAN 1476
Score = 33.1 bits (74), Expect = 0.35
Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 18/83 (21%)
Query: 243 GHSPGEAAVFPQGS------------GAGPFPWPPGAARSPALPYLPSAPVPLASPAQ-Q 289
GHS G V P G G GP P P + P+LP P P PL
Sbjct: 1248 GHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIP 1307
Query: 290 HSPFLTPVQGLDRHYLNLIGHAH 312
P P G RH+ HAH
Sbjct: 1308 PPPASAPPVGPHRHF-----HAH 1325
>gi|226371735 iroquois homeobox 3 [Homo sapiens]
Length = 501
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/99 (36%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 220 PPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSA 279
P + SL E S P AG SP AAV P P AA + A L SA
Sbjct: 347 PKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSP------AAAAAAAHRLVSA 400
Query: 280 PVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALNL 318
P+ PA + PF P G H L+L+G A P+ L L
Sbjct: 401 PLG-KFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGL 438
>gi|31543417 phospholipid scramblase 3 [Homo sapiens]
Length = 295
Score = 38.9 bits (89), Expect = 0.006
Identities = 27/68 (39%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 220 PPLGSLPEPDFSYQLHPAGPEFAGH-SPGEAAVFPQGSGAGP----FPWPPGAARSPALP 274
PP G P P Y + P PE A H PG+A V Q P FP P A A P
Sbjct: 6 PPKGYAPSPPPPYPVTPGYPEPALHPGPGQAPVPAQVPAPAPGFALFPSPGPVALGSAAP 65
Query: 275 YLPSAPVP 282
+LP VP
Sbjct: 66 FLPLPGVP 73
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 38.5 bits (88), Expect = 0.008
Identities = 32/90 (35%), Positives = 36/90 (40%), Gaps = 14/90 (15%)
Query: 214 GAEPA-FPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARS-- 270
GA+ A F P G P PDF Q F G PG + P G G P PG +
Sbjct: 40 GAQGADFQPPGLYPRPDFGEQ------PFGGSGPGPGSALP-ARGHGQEPGGPGGHYAAP 92
Query: 271 ----PALPYLPSAPVPLASPAQQHSPFLTP 296
PA P P AP+P A Q P P
Sbjct: 93 GEPCPAPPAPPPAPLPGARAYSQSDPKQPP 122
>gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo
sapiens]
Length = 520
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 9/108 (8%)
Query: 192 RMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAG-HSPGEAA 250
+ ET+D Y L +++++R A P G P P + PAG G SPG
Sbjct: 260 QQETEDQNYGIFLEMMEARSRGHASP-LAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQ 318
Query: 251 VFPQ--GSGAGPF---PWPPGAARSPALPYLPSAPVPLASPAQQHSPF 293
PQ + A P P PP A P P PSAP P S + P+
Sbjct: 319 PAPQLPLNAAPPSSVPPVPPSEALPP--PACPSAPAPRRSIISRPPPW 364
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 38.1 bits (87), Expect = 0.011
Identities = 36/94 (38%), Positives = 41/94 (43%), Gaps = 10/94 (10%)
Query: 211 ARLGAEPAFPPLGSLP--EPDFSYQLHPA--GPEFAGHSPGEAAVFPQGSGAGPFPWP-P 265
A + P P G LP EP LH A GP AA+ P G GP P P P
Sbjct: 49 AASASAPQRGPSGILPAAEPTIC-SLHQAWGGPGCRAQKGIPAALSP---GPGPIPAPIP 104
Query: 266 GAARSPALPYLPSAPVPLASPAQQHSPFLTPVQG 299
G A+ P P S P P+ PAQ SP P+ G
Sbjct: 105 GPAQIPG-PLPGSIPGPIPGPAQIPSPIPAPIPG 137
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 42 PHGTLSVEESRVRTP---VSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQI 98
PHG L E + R +H IEKRRRD++N ++EL VP A + L +
Sbjct: 14 PHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNA-MSRKLDKLTVL 72
Query: 99 RSRVRSL-VLSSATVPDQQA 117
R V+ + L AT P +A
Sbjct: 73 RMAVQHMKTLRGATNPYTEA 92
>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 42 PHGTLSVEESRVRTP---VSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQI 98
PHG L E + R +H IEKRRRD++N ++EL VP A + L +
Sbjct: 57 PHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNA-MSRKLDKLTVL 115
Query: 99 RSRVRSL-VLSSATVPDQQA 117
R V+ + L AT P +A
Sbjct: 116 RMAVQHMKTLRGATNPYTEA 135
>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 42 PHGTLSVEESRVRTP---VSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQI 98
PHG L E + R +H IEKRRRD++N ++EL VP A + L +
Sbjct: 57 PHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNA-MSRKLDKLTVL 115
Query: 99 RSRVRSL-VLSSATVPDQQA 117
R V+ + L AT P +A
Sbjct: 116 RMAVQHMKTLRGATNPYTEA 135
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/113 (30%), Positives = 40/113 (35%), Gaps = 19/113 (16%)
Query: 216 EPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPAL-- 273
EP PPL S+ + QL P +P +V Q P P PP + L
Sbjct: 917 EPPAPPLTSMQMQLYLQQLQKVQPP----TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972
Query: 274 -PYLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALNLHTPQHPP 325
P P P P P QQH P PV H P + H Q PP
Sbjct: 973 QPPPPPPPQPQPPPQQQHQPPPRPV------------HLQPMQFSTHIQQPPP 1013
Score = 29.3 bits (64), Expect = 5.0
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 253 PQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAH 312
PQ P P PP + A P + S+P P + P L P L + IGH
Sbjct: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA---TQVPVLEP--QLPGSVFDPIGHFT 824
Query: 313 PNALNLHTPQHPPVL 327
L+L P+ PP L
Sbjct: 825 QPILHLPQPELPPHL 839
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 11/123 (8%)
Query: 208 QSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGA 267
Q+ A + +P PP P P Q P P P +AA + S P P A
Sbjct: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSS-----PPPFIA 802
Query: 268 ARSPAL-PYLPSAPV-PLASPAQQHSPFL-TPVQGLDRHYLNLIGHAHPNALNLHTPQHP 324
+ P L P LP + P+ Q P L P L H H+ P LN H P
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQ---PILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 325 PVL 327
P L
Sbjct: 860 PAL 862
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 37.7 bits (86), Expect = 0.014
Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 15/88 (17%)
Query: 221 PLGSLPEPDFSYQLHPAGPEFA--GHSPGEAAVF-----PQGSGAGPFPWPPGAARSPAL 273
PL S P FS+ P + A G SP P+G GAG P PP +ARS L
Sbjct: 444 PLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQP-PPPSARSTPL 502
Query: 274 PYLPSAP-----VPLASPAQQHSPFLTP 296
P P +P PL SP H+P +P
Sbjct: 503 PGPPGSPRSSGGTPLHSPL--HTPRASP 528
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
Length = 729
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/100 (34%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 192 RMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAG-HSPGEAA 250
+ ET+D Y L +++++R A P G P P + PAG G SPG
Sbjct: 260 QQETEDQNYGIFLEMMEARSRGHASP-LAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQ 318
Query: 251 VFPQ--GSGAGPF---PWPPGAARSPALPYLPSAPVPLAS 285
PQ + A P P PP A P P PSAP P S
Sbjct: 319 PAPQLPLNAAPPSSVPPVPPSEALPP--PACPSAPAPRRS 356
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 37.0 bits (84), Expect = 0.024
Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 27/110 (24%)
Query: 219 FPPLGSLPEPDFSY-QLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLP 277
FPP G +P P S QL GP GH P GSG P P PP P +P+
Sbjct: 296 FPP-GGMPHPGMSQMQLAHHGPHGLGHPHAG----PPGSGGQPPPRPP-----PGMPH-- 343
Query: 278 SAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALNLHTPQHPPVL 327
P P+ P + PF +P+ HP + H + PP L
Sbjct: 344 PGPPPMGMP-PRGPPFGSPM-------------GHPGPMPPHGMRGPPPL 379
Score = 31.6 bits (70), Expect = 1.0
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 6/72 (8%)
Query: 253 PQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAH 312
P GS P P PPGA P +P P+P + TP G H GH+H
Sbjct: 239 PPGSFPPPVP-PPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGH-----GHSH 292
Query: 313 PNALNLHTPQHP 324
P+ HP
Sbjct: 293 PHPFPPGGMPHP 304
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/78 (30%), Positives = 28/78 (35%), Gaps = 15/78 (19%)
Query: 217 PAFPPLGSLPEPDFSYQLHPAG-----------PEFAGHSPGEA----AVFPQGSGAGPF 261
P PP GS P P P G P AGH P A A P + P
Sbjct: 235 PGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPH 294
Query: 262 PWPPGAARSPALPYLPSA 279
P+PPG P + + A
Sbjct: 295 PFPPGGMPHPGMSQMQLA 312
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 36.6 bits (83), Expect = 0.031
Identities = 34/110 (30%), Positives = 35/110 (31%), Gaps = 24/110 (21%)
Query: 207 LQSKARLGAEPAFPPLGSLPEPDFSYQLHPA----------GPEFAGHSPGEAAVFPQGS 256
L A A P PP P Y PA GP G AA
Sbjct: 17 LPPPAATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAYL 76
Query: 257 GAGPFPWPPGAARSPAL--------------PYLPSAPVPLASPAQQHSP 292
GA P P PPGAA P L P+ AP ASPA P
Sbjct: 77 GAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAGP 126
>gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens]
Length = 712
Score = 36.2 bits (82), Expect = 0.041
Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 29/110 (26%)
Query: 213 LGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPA 272
LGA P FP P+P LH +G P P P AA +
Sbjct: 615 LGAPPPFPTWPGCPQPP---PLHA-----------------WQAGTPPPPSPQPAAFPQS 654
Query: 273 LPYLPSAPVPLASPAQQHSPFLTPV---------QGLDRHYLNLIGHAHP 313
LP+ S P ASPA SP L P+ GL+ H N G P
Sbjct: 655 LPFPQSPAFPTASPAPPQSPGLQPLIIHHAQMVQLGLNNHMWNQRGSQAP 704
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,851,929
Number of Sequences: 37866
Number of extensions: 838288
Number of successful extensions: 5666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 4763
Number of HSP's gapped (non-prelim): 1176
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.