Guide to the Human Genome
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Name: HELT Sequence: fasta or formatted (327aa) NCBI GI: 71274142
Description:

HES/HEY-like transcription factor

Referenced in:

Helix-Loop-Helix Transcription Factors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1         33           2
 C cysteine            1.5          5           1
 D aspartate           2.4          8           1
 E glutamate           6.7         22           2
 F phenylalanine       3.4         11           1
 G glycine             7.0         23           2
 H histidine           4.6         15           1
 I isoleucine          1.8          6           1
 K lysine              4.6         15           1
 L leucine            11.9         39           3
 M methionine          1.8          6           1
 N asparagine          2.4          8           1
 P proline            10.7         35           2
 Q glutamine           4.3         14           2
 R arginine            6.7         22           3
 S serine              7.3         24           2
 T threonine           4.0         13           2
 V valine              5.5         18           2
 W tryptophan          0.3          1           1
 Y tyrosine            2.8          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HES/HEY-like transcription factor 
HEY1                  0.089   hairy/enhancer-of-split related with YRPW motif 1 i...
HEY1                  0.087   hairy/enhancer-of-split related with YRPW motif 1 i...
HEYL                  0.073   hairy/enhancer-of-split related with YRPW motif-like ...
HEY2                  0.065   hairy/enhancer-of-split related with YRPW motif 2 [Ho...
HES4                  0.045   hairy and enhancer of split 4 isoform 2 
HES1                  0.042   hairy and enhancer of split 1 
HES6                  0.042   hairy and enhancer of split 6 isoform b 
HES6                  0.039   hairy and enhancer of split 6 isoform a 
BHLHE41               0.039   basic helix-loop-helix domain containing, class B, 3...
HES4                  0.037   hairy and enhancer of split 4 isoform 1 
HES5                  0.036   hairy and enhancer of split 5 
BHLHE40               0.033   basic helix-loop-helix family, member e40 
HES7                  0.031   hairy and enhancer of split 7 
HES2                  0.028   hairy and enhancer of split homolog 2 
IQSEC2                0.023   IQ motif and Sec7 domain 2 isoform1 
IRX3                  0.022   iroquois homeobox 3 
PLSCR3                0.022   phospholipid scramblase 3 
HOXD4                 0.022   homeobox D4 
C9orf86               0.020   Rab-like GTP-binding protein 1 isoform 2 
TPRX1                 0.020   tetra-peptide repeat homeobox 
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
BRD4                  0.020   bromodomain-containing protein 4 isoform long 
BRSK1                 0.020   BR serine/threonine kinase 1 
C9orf86               0.019   Rab-like GTP-binding protein 1 isoform 1 
SF3B4                 0.019   splicing factor 3b, subunit 4 
FOXI3                 0.019   forkhead box I3 
TICAM1                0.017   toll-like receptor adaptor molecule 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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