Search of human proteins with 7110735

Search of human proteins with 7110735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7110735 ventral anterior homeobox 2 [Homo sapiens]                 580   e-166
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]     223   2e-58
gi|40217622 ventral anterior homeobox 1 isoform b [Homo sapiens]      148   5e-36
gi|4503615 even-skipped homeobox 1 [Homo sapiens]                      83   3e-16
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          82   4e-16
gi|14149611 empty spiracles homeobox 2 [Homo sapiens]                  82   4e-16
gi|7710121 engrailed homeobox 2 [Homo sapiens]                         82   6e-16
gi|84570137 homeobox B3 [Homo sapiens]                                 82   7e-16
gi|94536800 empty spiracles homolog 1 [Homo sapiens]                   80   2e-15
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        80   2e-15
gi|7706659 paired related homeobox 2 [Homo sapiens]                    80   2e-15
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                79   4e-15
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  79   5e-15
gi|23397672 homeobox D4 [Homo sapiens]                                 79   6e-15
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       78   1e-14
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    77   2e-14
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               77   2e-14
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             75   9e-14
gi|14149760 orthopedia homeobox [Homo sapiens]                         75   9e-14
gi|23510368 homeobox D11 [Homo sapiens]                                74   1e-13
gi|148613882 homeobox A4 [Homo sapiens]                                74   1e-13
gi|24497538 homeobox C4 [Homo sapiens]                                 73   3e-13
gi|24497540 homeobox C4 [Homo sapiens]                                 73   3e-13
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  72   4e-13
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        72   4e-13
gi|4885185 distal-less homeobox 3 [Homo sapiens]                       72   6e-13
gi|24497517 homeobox A5 [Homo sapiens]                                 72   6e-13
gi|122937319 even-skipped homeobox 2 [Homo sapiens]                    72   6e-13
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             72   7e-13
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             71   1e-12

>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
          Length = 290

 Score =  580 bits (1496), Expect = e-166
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRES 60
           MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRES
Sbjct: 1   MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRES 60

Query: 61  GADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEME 120
           GADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEME
Sbjct: 61  GADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEME 120

Query: 121 FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATS 180
           FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATS
Sbjct: 121 FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATS 180

Query: 181 NILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASPP 240
           NILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASPP
Sbjct: 181 NILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASPP 240

Query: 241 LPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLERKVGSASSCKKANT 290
           LPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLERKVGSASSCKKANT
Sbjct: 241 LPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLERKVGSASSCKKANT 290


>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
          Length = 334

 Score =  223 bits (567), Expect = 2e-58
 Identities = 150/283 (53%), Positives = 167/283 (59%), Gaps = 56/283 (19%)

Query: 51  ASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFT 110
           A S +G+ E    S       + D+CRRILVRDAKG+IREI+LPKGLDLDRPKRTRTSFT
Sbjct: 50  AFSASGAAEDCNKSKSNSA-ADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFT 108

Query: 111 AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRAS 170
           AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQ +D E R  
Sbjct: 109 AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELR-- 166

Query: 171 SSASEAFATSNILRLLEQGRLLSVPRAPSLL------ALTPSL--PGLPASHRGTSLGDP 222
           S  SE  AT ++LRLLEQGRLLS P  P+LL      AL  +L  P LPA   G + G  
Sbjct: 167 SVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSA 226

Query: 223 RNSSPRL-NPLSSASASPPL----PPPLPA-----------------------------V 248
             ++     P  +AS  PP     P P PA                              
Sbjct: 227 AAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVAS 286

Query: 249 CFSSAPLL----------DLPAGYELGSSAFEPYSWLERKVGS 281
             SSAPL           +L A Y L SSAFEPYS    K G+
Sbjct: 287 RLSSAPLTMAGSLAGNLQELSARY-LSSSAFEPYSRTNNKEGA 328


>gi|40217622 ventral anterior homeobox 1 isoform b [Homo sapiens]
          Length = 186

 Score =  148 bits (374), Expect = 5e-36
 Identities = 81/130 (62%), Positives = 94/130 (72%), Gaps = 10/130 (7%)

Query: 51  ASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFT 110
           A S +G+ E    S       + D+CRRILVRDAKG+IREI+LPKGLDLDRPKRTRTSFT
Sbjct: 50  AFSASGAAEDCNKSKSNSA-ADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFT 108

Query: 111 AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQV---------KVWFQNRRTKQKKDQ 161
           AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQ          K   + ++ K+KK+ 
Sbjct: 109 AEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQANSEENNERFKRGIKKQKKKRKKEP 168

Query: 162 SRDLEKRASS 171
           + D  +R  S
Sbjct: 169 ANDESRRGDS 178


>gi|4503615 even-skipped homeobox 1 [Homo sapiens]
          Length = 407

 Score = 82.8 bits (203), Expect = 3e-16
 Identities = 74/186 (39%), Positives = 90/186 (48%), Gaps = 10/186 (5%)

Query: 100 DRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
           D+ +R RT+FT EQ+ RLE EF R  YV    R ELA  LNL ET +KVWFQNRR K K+
Sbjct: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240

Query: 160 DQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLP-GLPASHRGTS 218
            +   L       A  AF T  +      G  L  P  PS L L    P GL A+   ++
Sbjct: 241 QR---LAMTWPHPADPAFYTYMMSHAAAAGG-LPYP-FPSHLPLPYYSPVGLGAASAASA 295

Query: 219 LGDPRNSSPRLNPLSSASA-SPPLPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLER 277
              P + S  L PL +    S P P P     F   PL   PA + LG+SA  P S L  
Sbjct: 296 AASPFSGS--LRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPA-HGLGASAGGPCSCLAC 352

Query: 278 KVGSAS 283
             G A+
Sbjct: 353 HSGPAN 358


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 69/209 (33%), Positives = 89/209 (42%), Gaps = 17/209 (8%)

Query: 3   DGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSA------SSPAG 56
           + G +    PA RA  GGGGG  G   G G     GGG       G S        +   
Sbjct: 45  EAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAER 104

Query: 57  SRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYR 116
           SRE G+    +  P   D        DAKG   E     G    + +R+RT+FT EQL  
Sbjct: 105 SREPGSPRLTEVSPELKDR-----KEDAKGMEDE-----GQTKIKQRRSRTNFTLEQLNE 154

Query: 117 LEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEA 176
           LE  F    Y     R EL+++L LSE +V+VWFQNRR K +K Q   L K     A+  
Sbjct: 155 LERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK-QENQLHKGVLIGAASQ 213

Query: 177 FATSNILRLLEQGRLLSVPRAPSLLALTP 205
           F    +   +  G L    +  S   +TP
Sbjct: 214 FEACRVAPYVNVGALRMPFQQDSHCNVTP 242


>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
          Length = 252

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 44/84 (52%), Positives = 57/84 (67%), Gaps = 3/84 (3%)

Query: 101 RPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKD 160
           +PKR RT+F+  QL RLE  F++  YVVG ER +LA  L+L+ETQVKVWFQNRRTK K+ 
Sbjct: 153 KPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ 212

Query: 161 QSRDLEKRASSSASEAFATSNILR 184
           +   LE+  S S  +   T +I R
Sbjct: 213 K---LEEEGSDSQQKKKGTHHINR 233


>gi|7710121 engrailed homeobox 2 [Homo sapiens]
          Length = 333

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 61/161 (37%), Positives = 84/161 (52%), Gaps = 14/161 (8%)

Query: 2   GDGGAERDRGPARRAESGGGGGRCGDRSGA--GDLRADGGGHSPTEVAGTSASSPAGSRE 59
           GDG      G ++     GG  + GD  G   G L+A G G     V+  S SS AG   
Sbjct: 152 GDG-----EGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAG--- 203

Query: 60  SGADSDGQPGPGEA-DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLE 118
             A+   QP    A  +C R   R + G        K  + +  KR RT+FTAEQL RL+
Sbjct: 204 --ANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKE-DKRPRTAFTAEQLQRLK 260

Query: 119 MEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
            EFQ  +Y+  + R  LA++L+L+E+Q+K+WFQN+R K KK
Sbjct: 261 AEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 10/77 (12%)

Query: 5   GAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSP---------A 55
           G  +D G       GG GG  G   GA      GG     ++ G+ +  P         A
Sbjct: 80  GRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGA 139

Query: 56  GSRESGADSDGQPGPGE 72
           G     A SD  PG GE
Sbjct: 140 GGPLPAAGSD-SPGDGE 155


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 69/229 (30%), Positives = 90/229 (39%), Gaps = 51/229 (22%)

Query: 16  AESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADH 75
           AE  GGGG  G   G+G     GGG       G    SP GS  S               
Sbjct: 150 AEGCGGGGGGGGGGGSGGSGGGGGG------GGGGDKSPPGSAAS--------------- 188

Query: 76  CRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTEL 135
                                      KR RT++T+ QL  LE EF   +Y+    R E+
Sbjct: 189 ---------------------------KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEM 221

Query: 136 ARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVP 195
           A  LNLSE Q+K+WFQNRR K KKDQ    +  ASSS   + A S    +      ++  
Sbjct: 222 ANLLNLSERQIKIWFQNRRMKYKKDQK--AKGLASSSGGPSPAGSPPQPMQSTAGFMNAL 279

Query: 196 RAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASPPLPPP 244
            + +    +PS P    +H+  +   P N  P L    +    PP P P
Sbjct: 280 HSMTPSYESPSPPAFGKAHQ-NAYALPSNYQPPLKGCGAPQKYPPTPAP 327


>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
          Length = 290

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 43/84 (51%), Positives = 56/84 (66%), Gaps = 3/84 (3%)

Query: 101 RPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKD 160
           +PKR RT+F+  QL RLE  F++  YVVG ER +LA  L+LSETQVKVWFQNRRTK K+ 
Sbjct: 191 KPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQ 250

Query: 161 QSRDLEKRASSSASEAFATSNILR 184
           +   LE+    S  +   + +I R
Sbjct: 251 K---LEEEGPESEQKKKGSHHINR 271


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 58/161 (36%), Positives = 82/161 (50%), Gaps = 27/161 (16%)

Query: 99  LDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQK 158
           L +P++ RT+FT  QL +LE  F+R +Y+  ++R ELA  LNL++TQVK W+QNRRTK K
Sbjct: 175 LKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWK 234

Query: 159 KDQSRDLEKRASSS---------ASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPG 209
           +  +  LE  A +           S  F   +++  L+ G  L + R PS  A  P+L  
Sbjct: 235 RQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPS--APPPAL-- 290

Query: 210 LPASHRGTSLGDPRNSSPR--LNPLSSASASPPLPPPLPAV 248
                        R   PR  ++ L  AS  PP  PPL  V
Sbjct: 291 ------------QRPLVPRILIHGLQGASEPPPPLPPLAGV 319


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 38/212 (17%)

Query: 29  SGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQ-PGPGEADHCRRILVRDAKGT 87
           + AG L A  G  +          S   S    A  DG+ P PG     +R         
Sbjct: 50  AAAGRLAARPGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKR--------- 100

Query: 88  IREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVK 147
                        + +R RT+F + QL  LE  F+R  Y     R ELAR++NLSE +V+
Sbjct: 101 -----------KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQ 149

Query: 148 VWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSL 207
           VWFQNRR K ++++   L  R++S          +L+   Q   +  P AP   AL+P  
Sbjct: 150 VWFQNRRAKFRRNERAMLASRSAS----------LLKSYSQEAAIEQPVAPRPTALSPDY 199

Query: 208 PGLPASHRGTSLGDPRNSSPRLNPLSSASASP 239
               AS        P ++ P  +P SS  A+P
Sbjct: 200 LSWTAS-------SPYSTVPPYSPGSSGPATP 224


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 64/168 (38%), Positives = 82/168 (48%), Gaps = 18/168 (10%)

Query: 3   DGGAERDRGPARRAESG-----GGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGS 57
           D   + D  P   A  G     GGGG  G R G+G   A     SP      +A+   G 
Sbjct: 156 DEDDDEDEAPETEAARGAEEARGGGGGLGAR-GSGCQGAAETDASPGATVDEAAAP--GP 212

Query: 58  RESGADSDGQPG----PGEADHCRRILVRDAKGTIREIVLPKGLDLD--RPKRTRTSFTA 111
           RE+   + G PG    PG A    +     AK   +      G D    +P+R RT+FT 
Sbjct: 213 RENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRT----GSDSKSGKPRRARTAFTY 268

Query: 112 EQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
           EQL  LE +F+  +Y+   ER  LA  L+L+ETQVK+WFQNRRTK KK
Sbjct: 269 EQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 316


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 79.0 bits (193), Expect = 5e-15
 Identities = 64/168 (38%), Positives = 82/168 (48%), Gaps = 18/168 (10%)

Query: 3   DGGAERDRGPARRAESG-----GGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGS 57
           D   + D  P   A  G     GGGG  G R G+G   A     SP      +A+   G 
Sbjct: 559 DEDDDEDEAPETEAARGAEEARGGGGGLGAR-GSGCQGAAETDASPGATVDEAAAP--GP 615

Query: 58  RESGADSDGQPG----PGEADHCRRILVRDAKGTIREIVLPKGLDLD--RPKRTRTSFTA 111
           RE+   + G PG    PG A    +     AK   +      G D    +P+R RT+FT 
Sbjct: 616 RENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRT----GSDSKSGKPRRARTAFTY 671

Query: 112 EQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
           EQL  LE +F+  +Y+   ER  LA  L+L+ETQVK+WFQNRRTK KK
Sbjct: 672 EQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 719


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 60/172 (34%), Positives = 81/172 (47%), Gaps = 8/172 (4%)

Query: 18  SGGGGGRCGDRSGAGDLRADGGGH--SPTEVAGTSASSPA----GSRESGADSDGQPGPG 71
           SG G G      G G      GGH  +P E      + P     G+R        QP  G
Sbjct: 65  SGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSG 124

Query: 72  EADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRE 131
            A     ++    K      V P       PKR+RT++T +Q+  LE EF   +Y+  R 
Sbjct: 125 TALKQPAVVYPWMKKVHVNSVNPNYTG-GEPKRSRTAYTRQQVLELEKEFHFNRYLTRRR 183

Query: 132 RTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEK-RASSSASEAFATSNI 182
           R E+A  L LSE Q+K+WFQNRR K KKD      K R+SSS+S +  +S++
Sbjct: 184 RIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSV 235


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 55/149 (36%), Positives = 81/149 (54%), Gaps = 8/149 (5%)

Query: 13  ARRAESGGGGGRCGDRS-GAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPG 71
           A+ +++GGGG   G  S GA   +    G+    + G++   P    +S      QP   
Sbjct: 218 AKPSDTGGGGSGGGAGSPGAQGTKYPEHGNPAILLMGSANGGPVVKTDSQ-----QPLVW 272

Query: 72  EA-DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGR 130
            A  +C R   R + G  R   L K  +    KR RT+FTAEQL RL+ EFQ  +Y+  +
Sbjct: 273 PAWVYCTRYSDRPSSGP-RTRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQ 331

Query: 131 ERTELARQLNLSETQVKVWFQNRRTKQKK 159
            R  LA++L+L+E+Q+K+WFQN+R K KK
Sbjct: 332 RRQTLAQELSLNESQIKIWFQNKRAKIKK 360


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 81/264 (30%), Positives = 106/264 (40%), Gaps = 42/264 (15%)

Query: 1   MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRES 60
           +G GGA R      RA  G GGG   D S   D    G      E A      P   +  
Sbjct: 108 LGCGGAARWYP---RAHGGYGGGLSPDTSDR-DSPETGEEMGRAEGAWPRGPGPGAVQRE 163

Query: 61  GADSDGQ-PGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEM 119
            A+   + P  G  +      V  A G  R  V   G+   R K+TRT F+  Q+++LE 
Sbjct: 164 AAELAARGPAAGTEEASELAEVPAAAGETRGGV---GVGGGRKKKTRTVFSRSQVFQLES 220

Query: 120 EFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFAT 179
            F   +Y+   ER  LA  L L+ETQVK+WFQNRR K K+  + +LE  +          
Sbjct: 221 TFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAAS---------- 270

Query: 180 SNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASP 239
                       LS P A  L+        +P  +  +         P   P   A A+P
Sbjct: 271 ------------LSPPGAQRLVR-------VPVLYHESPPAAAAAGPPATLPFPLAPAAP 311

Query: 240 PLPPPLPAVCFSSA---PLLDLPA 260
             PPPL  + FS A   PL   PA
Sbjct: 312 APPPPL--LGFSGALAYPLAAFPA 333


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 68/208 (32%), Positives = 101/208 (48%), Gaps = 19/208 (9%)

Query: 10  RGPARRAESGGG---GGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDG 66
           RG +    +GG    G    + + + DL  +  G S +E++    +S +G R    + DG
Sbjct: 111 RGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMS----ASVSGDRSPRTEDDG 166

Query: 67  QPGPGEADHCRRILVRDAKGT------IREIVLPKGLDLDRPKRTRTSFTAEQLYRLEME 120
             GP  A H   +      G       + E          R KR+R +F+  Q++ LE  
Sbjct: 167 V-GPRGA-HVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERR 224

Query: 121 FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATS 180
           F   +Y+ G ER +LA  L L+ETQVK+WFQNRR K K+ Q    +  AS+ A++  A  
Sbjct: 225 FNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMA-ADLLASAPAAKKVAVK 283

Query: 181 NILRLLEQGRLL--SVPRAPSLLALTPS 206
            ++R  +Q + L   V R PSLL L PS
Sbjct: 284 VLVR-DDQRQYLPGEVLRPPSLLPLQPS 310


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 71/231 (30%), Positives = 95/231 (41%), Gaps = 50/231 (21%)

Query: 22  GGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRRILV 81
           GG  GD +   D   +G    P E   T  S+PA    S  D D QPGP    +  +   
Sbjct: 39  GGHPGDLAPNSD-PVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQ 97

Query: 82  RDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNL 141
           +  +               + KR RT FT  QL  LE  F +  Y     R ELA ++ L
Sbjct: 98  QQGQ--------------QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGL 143

Query: 142 SETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLL 201
           +E++V+VWFQNRR K KK +                 T+N+             RAP  L
Sbjct: 144 TESRVQVWFQNRRAKWKKRKK----------------TTNVF------------RAPGTL 175

Query: 202 ALTPSLPGLP--ASHRGTSLGDPRNSSPRLNPLSSASASP-----PLPPPL 245
             TP LP  P  A+    ++GD   S    +   +A+A P     PLPP L
Sbjct: 176 LPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPAL 226


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 71/231 (30%), Positives = 95/231 (41%), Gaps = 50/231 (21%)

Query: 22  GGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRRILV 81
           GG  GD +   D   +G    P E   T  S+PA    S  D D QPGP    +  +   
Sbjct: 39  GGHPGDLAPNSD-PVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQ 97

Query: 82  RDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNL 141
           +  +               + KR RT FT  QL  LE  F +  Y     R ELA ++ L
Sbjct: 98  QQGQ--------------QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGL 143

Query: 142 SETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLL 201
           +E++V+VWFQNRR K KK +                 T+N+             RAP  L
Sbjct: 144 TESRVQVWFQNRRAKWKKRKK----------------TTNVF------------RAPGTL 175

Query: 202 ALTPSLPGLP--ASHRGTSLGDPRNSSPRLNPLSSASASP-----PLPPPL 245
             TP LP  P  A+    ++GD   S    +   +A+A P     PLPP L
Sbjct: 176 LPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPAL 226


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 53/149 (35%), Positives = 72/149 (48%), Gaps = 24/149 (16%)

Query: 12  PARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRE-SGADSDGQPGP 70
           P    +  G   +   R+GAG     GGG SP   A T  S P G+ E SG D +G PG 
Sbjct: 198 PPAPPQPEGAADKGDPRTGAG-----GGGGSPCTKA-TPGSEPKGAAEGSGGDGEGPPGE 251

Query: 71  GEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGR 130
             A+                 V P+     R ++ R  +T  Q+  LE EF    Y+   
Sbjct: 252 AGAEKSS------------SAVAPQ-----RSRKKRCPYTKYQIRELEREFFFNVYINKE 294

Query: 131 ERTELARQLNLSETQVKVWFQNRRTKQKK 159
           +R +L+R LNL++ QVK+WFQNRR K+KK
Sbjct: 295 KRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323



 Score = 35.4 bits (80), Expect = 0.059
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 3   DGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGG---HSPTEVAGTSASSPAGSRE 59
           D G ER + P R    GGGGG  G  S  G     GGG   ++P   A  +A++ A + E
Sbjct: 65  DYGLERAKWPYR---GGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAE 121

Query: 60  SGA 62
             A
Sbjct: 122 EAA 124


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 38/77 (49%), Positives = 50/77 (64%)

Query: 102 PKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQ 161
           PKR+RT++T +Q+  LE EF   +Y+  R R E+A  L LSE QVK+WFQNRR K KKD 
Sbjct: 215 PKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDH 274

Query: 162 SRDLEKRASSSASEAFA 178
                K  SS+++ A A
Sbjct: 275 KLPNTKMRSSNSASASA 291


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 10/146 (6%)

Query: 25  CGDRSGAGDLRADG----GGHSPT------EVAGTSASSPAGSRESGADSDGQPGPGEAD 74
           C    G G+ R  G    G H P       E A  S +S + S    A S   P    + 
Sbjct: 69  CTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSA 128

Query: 75  HCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTE 134
             ++ +V      I    +    +   PKR+RT++T +Q+  LE EF   +Y+  R R E
Sbjct: 129 ASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIE 188

Query: 135 LARQLNLSETQVKVWFQNRRTKQKKD 160
           +A  L LSE Q+K+WFQNRR K KKD
Sbjct: 189 IAHSLCLSERQIKIWFQNRRMKWKKD 214


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 10/146 (6%)

Query: 25  CGDRSGAGDLRADG----GGHSPT------EVAGTSASSPAGSRESGADSDGQPGPGEAD 74
           C    G G+ R  G    G H P       E A  S +S + S    A S   P    + 
Sbjct: 69  CTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSA 128

Query: 75  HCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTE 134
             ++ +V      I    +    +   PKR+RT++T +Q+  LE EF   +Y+  R R E
Sbjct: 129 ASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIE 188

Query: 135 LARQLNLSETQVKVWFQNRRTKQKKD 160
           +A  L LSE Q+K+WFQNRR K KKD
Sbjct: 189 IAHSLCLSERQIKIWFQNRRMKWKKD 214


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 48/112 (42%), Positives = 62/112 (55%), Gaps = 10/112 (8%)

Query: 54  PAGSRESGADSDGQPG----PGEADHCRRILVRDAKGTIREIVLPKGLDLD--RPKRTRT 107
           P G RE+   + G PG    PG A    +     AK   +      G D    +P+R RT
Sbjct: 47  PPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRT----GSDSKSGKPRRART 102

Query: 108 SFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
           +FT EQL  LE +F+  +Y+   ER  LA  L+L+ETQVK+WFQNRRTK KK
Sbjct: 103 AFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 154


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 53/156 (33%), Positives = 75/156 (48%), Gaps = 14/156 (8%)

Query: 101 RPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKD 160
           +P++ RT+F+  QL +LE  F+R +Y+  ++R +LA  LNL++TQVK W+QNRRTK K+ 
Sbjct: 231 KPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290

Query: 161 QSRDLEKRAS----SSASEAFATSNILRLLEQGRLLSVPRAPSLLAL------TPSLP-- 208
            +  LE  A     S+    F +         G + S   A +  A+      TP  P  
Sbjct: 291 TAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHP 350

Query: 209 --GLPASHRGTSLGDPRNSSPRLNPLSSASASPPLP 242
               P   R    G      P LNPLSS     P P
Sbjct: 351 QLQRPLVPRVLIHGLGPGGQPALNPLSSPIPGTPHP 386


>gi|4885185 distal-less homeobox 3 [Homo sapiens]
          Length = 287

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 72/219 (32%), Positives = 101/219 (46%), Gaps = 25/219 (11%)

Query: 46  VAGTSASSP-------AGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLD 98
           +AGT A SP       A  R+ GA  + QP P +      + V++       +V  K   
Sbjct: 74  LAGTGAYSPKSEYTYGASYRQYGAYRE-QPLPAQDP----VSVKEEPEAEVRMVNGKPKK 128

Query: 99  LDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQK 158
           + +P   RT +++ QL  L+  FQ+ QY+   ER ELA QL L++TQVK+WFQNRR+K K
Sbjct: 129 VRKP---RTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFK 185

Query: 159 ---KDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHR 215
              K+    LE   ++S S A  +     L +     +   A S L      P LP S  
Sbjct: 186 KLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLP-----PPLPYSAS 240

Query: 216 GTSLGDPRNSSPRLNPLSSASASPPLPPPLPAVCFSSAP 254
            + L DP NS      LS         PP PA    ++P
Sbjct: 241 PSYLDDPTNSWYHAQNLSGPHLQQ--QPPQPATLHHASP 277


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 58/164 (35%), Positives = 79/164 (48%), Gaps = 18/164 (10%)

Query: 20  GGGGRCGDRSGAGDLRADGGGH--SPTEVAGTSASS----PAGSRESGADSDGQPGPGEA 73
           GG     + SGA    AD G    S  E  GT++ +    PA S ++ A S+  P P   
Sbjct: 117 GGKNSLSNSSGAS---ADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQ 173

Query: 74  DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERT 133
                 + R    +   I  P+G      KR RT++T  Q   LE EF   +Y+  R R 
Sbjct: 174 PQIYPWM-RKLHISHDNIGGPEG------KRARTAYTRYQTLELEKEFHFNRYLTRRRRI 226

Query: 134 ELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAF 177
           E+A  L LSE Q+K+WFQNRR K KKD    L+  + ++A  AF
Sbjct: 227 EIAHALCLSERQIKIWFQNRRMKWKKDNK--LKSMSMAAAGGAF 268


>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
          Length = 476

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 48/149 (32%), Positives = 63/149 (42%), Gaps = 25/149 (16%)

Query: 13  ARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGE 72
           A R+  G G  +  + +G G   +     + T  +G+   S  G       S    G G 
Sbjct: 124 ALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGSGS 183

Query: 73  ADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRER 132
                                      D+ +R RT+FT EQ+ RLE EF R  YV    R
Sbjct: 184 G-------------------------ADQVRRYRTAFTREQIARLEKEFYRENYVSRPRR 218

Query: 133 TELARQLNLSETQVKVWFQNRRTKQKKDQ 161
            ELA  LNL ET +KVWFQNRR K K+ +
Sbjct: 219 CELAAALNLPETTIKVWFQNRRMKDKRQR 247


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 53/143 (37%), Positives = 74/143 (51%), Gaps = 16/143 (11%)

Query: 42  SPTEVAGTSASSPAGSRE----SGADSDGQP-------GPGEADHCRRILVRDAKGTIRE 90
           S  E    SA  PAGS +    SG DS+          GPG     +  L + + GT  E
Sbjct: 187 SDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKL-KGSLGTGAE 245

Query: 91  IVLPKGLDLDRP----KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQV 146
              P    +  P    +R RT+FT+EQL  LE EF   +Y+   ER+++A  L LSE QV
Sbjct: 246 EGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQV 305

Query: 147 KVWFQNRRTKQKKDQSRDLEKRA 169
           K+WFQNRR K K+ ++ ++  R+
Sbjct: 306 KIWFQNRRAKWKRIKAGNVSSRS 328


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 49/123 (39%), Positives = 60/123 (48%), Gaps = 16/123 (13%)

Query: 38  GGGHSPTEVAGTSASSPAGSRESGADSDGQPG-PGEADHCRRILVRDAKGTIREIVLPKG 96
           G   SP   AG  AS        G      PG PG     RR L  +             
Sbjct: 113 GLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA----------- 161

Query: 97  LDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTK 156
               +P+R RT+FT EQL  LE +F+  +Y+   ER  LA  L+L+ETQVK+WFQNRRTK
Sbjct: 162 ----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTK 217

Query: 157 QKK 159
            KK
Sbjct: 218 WKK 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,312,912
Number of Sequences: 37866
Number of extensions: 798141
Number of successful extensions: 8796
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 422
Number of HSP's successfully gapped in prelim test: 454
Number of HSP's that attempted gapping in prelim test: 6086
Number of HSP's gapped (non-prelim): 2609
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.