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Search of human proteins with 13899309
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens] 1110 0.0
gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1 i... 209 4e-54
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is... 209 4e-54
gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho... 123 4e-28
gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 121 1e-27
gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 121 1e-27
gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is... 117 2e-26
gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is... 117 2e-26
gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens] 113 4e-25
gi|4506737 ribosomal protein S6 kinase, 70kDa, polypeptide 1 [Ho... 107 4e-23
gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H... 101 2e-21
gi|47157325 protein kinase C, delta [Homo sapiens] 101 2e-21
gi|31377782 protein kinase C, delta [Homo sapiens] 101 2e-21
gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b... 99 1e-20
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 99 1e-20
gi|5453976 protein kinase C, theta [Homo sapiens] 96 6e-20
gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4 is... 96 1e-19
gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4 iso... 96 1e-19
gi|28557781 protein kinase C, eta [Homo sapiens] 95 1e-19
gi|4502023 AKT2 kinase [Homo sapiens] 95 1e-19
gi|4506067 protein kinase C, alpha [Homo sapiens] 95 1e-19
gi|13384594 protein kinase C, gamma [Homo sapiens] 95 1e-19
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 93 7e-19
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 93 7e-19
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 93 7e-19
gi|75709228 protein kinase C, zeta isoform 2 [Homo sapiens] 92 9e-19
gi|75709226 protein kinase C, zeta isoform 2 [Homo sapiens] 92 9e-19
gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens] 92 9e-19
gi|4885563 protein kinase C, epsilon [Homo sapiens] 92 9e-19
gi|133908623 protein kinase C, iota [Homo sapiens] 91 2e-18
>gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
Length = 541
Score = 1110 bits (2870), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLA 60
MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLA
Sbjct: 1 MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLA 60
Query: 61 LERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQR 120
LERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQR
Sbjct: 61 LERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQR 120
Query: 121 PLSSGASPSAVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSED 180
PLSSGASPSAVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSED
Sbjct: 121 PLSSGASPSAVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSED 180
Query: 181 SIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAP 240
SIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAP
Sbjct: 181 SIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAP 240
Query: 241 GQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQAR 300
GQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQAR
Sbjct: 241 GQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQAR 300
Query: 301 RAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQ 360
RAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQ
Sbjct: 301 RAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQ 360
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYS 420
WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYS
Sbjct: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYS 420
Query: 421 APEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLL 480
APEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLL
Sbjct: 421 APEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLL 480
Query: 481 TELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLRTLIHWLSGPKPDCP 540
TELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLRTLIHWLSGPKPDCP
Sbjct: 481 TELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLRTLIHWLSGPKPDCP 540
Query: 541 G 541
G
Sbjct: 541 G 541
>gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1
isoform b [Homo sapiens]
Length = 1054
Score = 209 bits (533), Expect = 4e-54
Identities = 91/165 (55%), Positives = 125/165 (75%)
Query: 353 VREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCG 412
+ E +++WAAEM+VAL+ALH +G++CRDL+P N+LL+ GHI+LTYF +WSEVE C
Sbjct: 889 IPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDS 948
Query: 413 EAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWL 472
+A++ +Y APEVG I+E TEACDWWS G++L+ELLTG L + HP+GI HT L +PE +
Sbjct: 949 DAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECV 1008
Query: 473 SRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLV 517
S A SL+ +LLQF P RLG G GV +KSHPFF+ + W++L+
Sbjct: 1009 SEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAELM 1053
Score = 121 bits (303), Expect = 2e-27
Identities = 73/185 (39%), Positives = 102/185 (55%), Gaps = 28/185 (15%)
Query: 42 PDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKL 101
P + KRDYL A I+LAL+++ +DYEAA + Y+ GVD+LL G+ + + RREAVK
Sbjct: 220 PKLGKRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKR 279
Query: 102 KITKYLRRAEEIFNCH---------------LQRPLSSGASPS-------------AVQL 133
+ +YL RAE I + + RPL + SP+ V L
Sbjct: 280 RTAEYLMRAESISSLYGKPQLDDVSQPPGSLSSRPLWNLRSPAEELKAFRVLGVIDKVLL 339
Query: 134 VQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGT 193
V D T TF++K L + SR R TIIP VP M L +Y +SE+S+FL L+H +GG
Sbjct: 340 VMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGK 399
Query: 194 LWSHL 198
LWS++
Sbjct: 400 LWSYI 404
>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 isoform
a [Homo sapiens]
Length = 1066
Score = 209 bits (533), Expect = 4e-54
Identities = 91/165 (55%), Positives = 125/165 (75%)
Query: 353 VREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCG 412
+ E +++WAAEM+VAL+ALH +G++CRDL+P N+LL+ GHI+LTYF +WSEVE C
Sbjct: 901 IPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDS 960
Query: 413 EAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWL 472
+A++ +Y APEVG I+E TEACDWWS G++L+ELLTG L + HP+GI HT L +PE +
Sbjct: 961 DAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECV 1020
Query: 473 SRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLV 517
S A SL+ +LLQF P RLG G GV +KSHPFF+ + W++L+
Sbjct: 1021 SEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAELM 1065
Score = 121 bits (303), Expect = 2e-27
Identities = 73/185 (39%), Positives = 102/185 (55%), Gaps = 28/185 (15%)
Query: 42 PDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKL 101
P + KRDYL A I+LAL+++ +DYEAA + Y+ GVD+LL G+ + + RREAVK
Sbjct: 232 PKLGKRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKR 291
Query: 102 KITKYLRRAEEIFNCH---------------LQRPLSSGASPS-------------AVQL 133
+ +YL RAE I + + RPL + SP+ V L
Sbjct: 292 RTAEYLMRAESISSLYGKPQLDDVSQPPGSLSSRPLWNLRSPAEELKAFRVLGVIDKVLL 351
Query: 134 VQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGT 193
V D T TF++K L + SR R TIIP VP M L +Y +SE+S+FL L+H +GG
Sbjct: 352 VMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGK 411
Query: 194 LWSHL 198
LWS++
Sbjct: 412 LWSYI 416
>gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Homo
sapiens]
Length = 740
Score = 123 bits (309), Expect = 4e-28
Identities = 71/169 (42%), Positives = 96/169 (56%), Gaps = 7/169 (4%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEV---EPQCC 411
EE VK + AE+ +AL+ LH G++ RDL P N+LLD+ GHI+LT FG E E +
Sbjct: 167 EEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAY 226
Query: 412 GEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHTQLQ 467
Y APEV T++ DWWSFG L++E+LTG + + +L
Sbjct: 227 SFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLG 286
Query: 468 LPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+P++LS A SLL L + P RLG G GV ++K H FFSTI W+KL
Sbjct: 287 MPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKL 335
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 27/167 (16%)
Query: 369 LEALHEQGVLCRDLHPGNLL-LDQAGH---IRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
+E LH QGV+ RDL P N+L +D++G+ IR+ FG ++ + G + Y+A
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAEN-GLLMTPCYTANFV 585
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPE---------W 471
PEV ACD WS G LLY +LTG + P ++ W
Sbjct: 586 APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYW 645
Query: 472 --LSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+S A L++++L +P +RL + + HP+ + W +L
Sbjct: 646 NSVSDTAKDLVSKMLHVDPHQRL-----TAALVLRHPWI--VHWDQL 685
>gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform b [Homo sapiens]
Length = 741
Score = 121 bits (304), Expect = 1e-27
Identities = 70/172 (40%), Positives = 95/172 (55%), Gaps = 13/172 (7%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEV------EP 408
EE VK + AE+ +AL+ LH G++ RDL P N+LLD+ GHI++T FG E
Sbjct: 166 EEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAY 225
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHT 464
CG Y APEV T++ DWWSFG L++E+LTG + +
Sbjct: 226 SFCGTIE---YMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 282
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+L +P++LS A SLL L + P RLG G GV ++K HPFF TI W+ L
Sbjct: 283 KLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTL 334
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 20/143 (13%)
Query: 369 LEALHEQGVLCRDLHPGNLLL-DQAGH---IRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
++ LH QGV+ RDL P N+L D++G IR+ FG ++ G + Y+A
Sbjct: 528 MDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGN-GLLMTPCYTANFV 586
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQL---------PEW 471
PEV ACD WS G LLY +L G + P ++ W
Sbjct: 587 APEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW 646
Query: 472 --LSRPAASLLTELLQFEPTRRL 492
+S A +++++L +P +RL
Sbjct: 647 DSISDAAKDVVSKMLHVDPHQRL 669
>gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform a [Homo sapiens]
Length = 733
Score = 121 bits (304), Expect = 1e-27
Identities = 70/172 (40%), Positives = 95/172 (55%), Gaps = 13/172 (7%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEV------EP 408
EE VK + AE+ +AL+ LH G++ RDL P N+LLD+ GHI++T FG E
Sbjct: 158 EEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAY 217
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHT 464
CG Y APEV T++ DWWSFG L++E+LTG + +
Sbjct: 218 SFCGTIE---YMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+L +P++LS A SLL L + P RLG G GV ++K HPFF TI W+ L
Sbjct: 275 KLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTL 326
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 20/143 (13%)
Query: 369 LEALHEQGVLCRDLHPGNLLL-DQAGH---IRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
++ LH QGV+ RDL P N+L D++G IR+ FG ++ G + Y+A
Sbjct: 520 MDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGN-GLLMTPCYTANFV 578
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQL---------PEW 471
PEV ACD WS G LLY +L G + P ++ W
Sbjct: 579 APEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW 638
Query: 472 --LSRPAASLLTELLQFEPTRRL 492
+S A +++++L +P +RL
Sbjct: 639 DSISDAAKDVVSKMLHVDPHQRL 661
>gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1
isoform b [Homo sapiens]
Length = 744
Score = 117 bits (294), Expect = 2e-26
Identities = 66/169 (39%), Positives = 93/169 (55%), Gaps = 7/169 (4%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEV---EPQCC 411
EE VK + AE+ + L+ LH G++ RDL P N+LLD+ GHI+LT FG E E +
Sbjct: 170 EEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAY 229
Query: 412 GEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHTQLQ 467
Y APEV + + DWWS+G L++E+LTG + + +L
Sbjct: 230 SFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 289
Query: 468 LPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+P++LS A SLL L + P RLG G G ++K H F+STI W+KL
Sbjct: 290 MPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKL 338
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 20/143 (13%)
Query: 369 LEALHEQGVLCRDLHPGNLL-LDQAGH---IRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
+E LH QGV+ RDL P N+L +D++G+ +R+ FG ++ + G + Y+A
Sbjct: 532 VEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAEN-GLLMTPCYTANFV 590
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQL---------PEW 471
PEV E CD WS G LLY +L G + PS ++ W
Sbjct: 591 APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW 650
Query: 472 --LSRPAASLLTELLQFEPTRRL 492
+S A L++++L +P +RL
Sbjct: 651 NTVSETAKDLVSKMLHVDPHQRL 673
Score = 30.0 bits (66), Expect = 5.6
Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 11/77 (14%)
Query: 131 VQLVQDPATGGTFVVKSLPRCHMVSRER---------LTIIPHGVPYMTKLLRYFVSEDS 181
V+ V P +G + +K L + + R+R L + H P++ KL F +E
Sbjct: 88 VRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNH--PFVVKLHYAFQTEGK 145
Query: 182 IFLHLEHVQGGTLWSHL 198
++L L+ ++GG L++ L
Sbjct: 146 LYLILDFLRGGDLFTRL 162
>gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1
isoform a [Homo sapiens]
Length = 735
Score = 117 bits (294), Expect = 2e-26
Identities = 66/169 (39%), Positives = 93/169 (55%), Gaps = 7/169 (4%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEV---EPQCC 411
EE VK + AE+ + L+ LH G++ RDL P N+LLD+ GHI+LT FG E E +
Sbjct: 161 EEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAY 220
Query: 412 GEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHTQLQ 467
Y APEV + + DWWS+G L++E+LTG + + +L
Sbjct: 221 SFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG 280
Query: 468 LPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+P++LS A SLL L + P RLG G G ++K H F+STI W+KL
Sbjct: 281 MPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKL 329
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 20/143 (13%)
Query: 369 LEALHEQGVLCRDLHPGNLL-LDQAGH---IRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
+E LH QGV+ RDL P N+L +D++G+ +R+ FG ++ + G + Y+A
Sbjct: 523 VEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAEN-GLLMTPCYTANFV 581
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQL---------PEW 471
PEV E CD WS G LLY +L G + PS ++ W
Sbjct: 582 APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW 641
Query: 472 --LSRPAASLLTELLQFEPTRRL 492
+S A L++++L +P +RL
Sbjct: 642 NTVSETAKDLVSKMLHVDPHQRL 664
Score = 32.0 bits (71), Expect = 1.5
Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 16/124 (12%)
Query: 89 VDPNKERREAVKLKITKYLRRAEEIFN---CHLQRPLSSGASPSA--VQLVQDPATGGTF 143
+ P+K+ ++ IT +++ E + L + L G+ V+ V P +G +
Sbjct: 32 LQPSKDEGVLKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLY 91
Query: 144 VVKSLPRCHMVSRER---------LTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTL 194
+K L + + R+R L + H P++ KL F +E ++L L+ ++GG L
Sbjct: 92 AMKVLKKATLKVRDRVRTKMERDILADVNH--PFVVKLHYAFQTEGKLYLILDFLRGGDL 149
Query: 195 WSHL 198
++ L
Sbjct: 150 FTRL 153
>gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]
Length = 745
Score = 113 bits (283), Expect = 4e-25
Identities = 68/172 (39%), Positives = 96/172 (55%), Gaps = 15/172 (8%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQ----- 409
EE VK + AE+ +AL+ LH+ G++ RDL P N+LLD+ GHI+LT FG E Q
Sbjct: 172 EEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAY 231
Query: 410 -CCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHT 464
CG Y APEV +++ DWWS+G L++E+LTG ++ +
Sbjct: 232 SFCGTVE---YMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKA 288
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+L +P++LS A SLL L + P RL G GV ++K H FF+ I W KL
Sbjct: 289 KLGMPQFLSAEAQSLLRMLFKRNPANRL--GSEGVEEIKRHLFFANIDWDKL 338
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 20/142 (14%)
Query: 369 LEALHEQGVLCRDLHPGNLL-LDQ---AGHIRLTYFGQWSEVEPQCCGEAVDNLYSA--- 421
++ LH QGV+ RDL P N+L +D+ A IR+ FG ++ + G + Y+A
Sbjct: 531 VDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGEN-GLLLTPCYTANFV 589
Query: 422 -PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQL---------PEW 471
PEV ACD WS G L Y +L G + P+ L++ W
Sbjct: 590 APEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNW 649
Query: 472 --LSRPAASLLTELLQFEPTRR 491
+S A LL+ +L +P +R
Sbjct: 650 DNISDGAKDLLSHMLHMDPHQR 671
>gi|4506737 ribosomal protein S6 kinase, 70kDa, polypeptide 1 [Homo
sapiens]
Length = 525
Score = 107 bits (266), Expect = 4e-23
Identities = 63/179 (35%), Positives = 97/179 (54%), Gaps = 13/179 (7%)
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEPQCCGEA 414
+ AE+ +AL LH++G++ RDL P N++L+ GH++LT FG E V CG
Sbjct: 198 YLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTI 257
Query: 415 VDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMA--LSQSHPSGIQA--HTQLQLPE 470
Y APE+ S A DWWS G+L+Y++LTG ++ I +L LP
Sbjct: 258 E---YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPP 314
Query: 471 WLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLRTLI 529
+L++ A LL +LL+ RLG G G ++++HPFF I W +L+ +E + L+
Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLL 373
>gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo
sapiens]
Length = 482
Score = 101 bits (252), Expect = 2e-21
Identities = 61/176 (34%), Positives = 92/176 (52%), Gaps = 13/176 (7%)
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEPQCCGEA 414
+ AE+ +AL LH QG++ RDL P N++L GHI+LT FG E V CG
Sbjct: 174 YLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTI 233
Query: 415 VDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG----MALSQSHPSGIQAHTQLQLPE 470
Y APE+ S A DWWS G+L+Y++LTG A ++ +L LP
Sbjct: 234 E---YMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPP 290
Query: 471 WLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLR 526
+L+ A L+ + L+ P++R+G G G + ++ HPFF + W L+ ++ R
Sbjct: 291 YLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFR 346
>gi|47157325 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 101 bits (251), Expect = 2e-21
Identities = 63/177 (35%), Positives = 93/177 (52%), Gaps = 19/177 (10%)
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNL-- 418
+AAE++ L+ LH +G++ RDL N+LLD+ GHI++ FG E GE+ +
Sbjct: 453 YAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKE---NIFGESRASTFC 509
Query: 419 ----YSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHP-----SGIQAHTQLQLP 469
Y APE+ + T + DWWSFG LLYE+L G + I+ T P
Sbjct: 510 GTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTP-HYP 568
Query: 470 EWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLR 526
W+++ + +L +L + EPT+RLG+ +K HPFF TI W+ L LE R
Sbjct: 569 RWITKESKDILEKLFEREPTKRLGV----TGNIKIHPFFKTINWTLLEKRRLEPPFR 621
Score = 33.5 bits (75), Expect = 0.51
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 11/69 (15%)
Query: 140 GGTFVVKSLPR----------CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHV 189
G F +K+L + C MV + LT+ P++T L+ F ++D +F +E +
Sbjct: 372 GEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAEN-PFLTHLICTFQTKDHLFFVMEFL 430
Query: 190 QGGTLWSHL 198
GG L H+
Sbjct: 431 NGGDLMYHI 439
>gi|31377782 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 101 bits (251), Expect = 2e-21
Identities = 63/177 (35%), Positives = 93/177 (52%), Gaps = 19/177 (10%)
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNL-- 418
+AAE++ L+ LH +G++ RDL N+LLD+ GHI++ FG E GE+ +
Sbjct: 453 YAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKE---NIFGESRASTFC 509
Query: 419 ----YSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHP-----SGIQAHTQLQLP 469
Y APE+ + T + DWWSFG LLYE+L G + I+ T P
Sbjct: 510 GTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTP-HYP 568
Query: 470 EWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLR 526
W+++ + +L +L + EPT+RLG+ +K HPFF TI W+ L LE R
Sbjct: 569 RWITKESKDILEKLFEREPTKRLGV----TGNIKIHPFFKTINWTLLEKRRLEPPFR 621
Score = 33.5 bits (75), Expect = 0.51
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 11/69 (15%)
Query: 140 GGTFVVKSLPR----------CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHV 189
G F +K+L + C MV + LT+ P++T L+ F ++D +F +E +
Sbjct: 372 GEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAEN-PFLTHLICTFQTKDHLFFVMEFL 430
Query: 190 QGGTLWSHL 198
GG L H+
Sbjct: 431 NGGDLMYHI 439
>gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b
[Homo sapiens]
Length = 549
Score = 98.6 bits (244), Expect = 1e-20
Identities = 65/192 (33%), Positives = 96/192 (50%), Gaps = 20/192 (10%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFG-------QWSEVE 407
E +V+ + E+++ALE LH+ G++ RD+ N+LLD GH+ LT FG +E
Sbjct: 151 EHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERA 210
Query: 408 PQCCGEAVDNLYSAPEV--GGISELTEACDWWSFGSLLYELLTGMA--------LSQSHP 457
CG Y AP++ GG S +A DWWS G L+YELLTG + SQ+
Sbjct: 211 YSFCGTIE---YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEI 267
Query: 458 SGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLV 517
S ++ P+ +S A L+ LL +P +RLG G ++K H FF I W L
Sbjct: 268 SRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLA 327
Query: 518 GTSLETHLRTLI 529
+ + +I
Sbjct: 328 AKKVPAPFKPVI 339
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 12/98 (12%)
Query: 113 IFNCHLQRPLSSGASPSA--VQLVQDPATGGTFVVKSLPRCHMVSRERLT--------II 162
I N L + L +GA V+ + TG + +K L + +V + + T ++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 163 PH--GVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
H P++ L F +E + L L+++ GG L++HL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHL 143
>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
[Homo sapiens]
Length = 802
Score = 98.6 bits (244), Expect = 1e-20
Identities = 65/192 (33%), Positives = 96/192 (50%), Gaps = 20/192 (10%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFG-------QWSEVE 407
E +V+ + E+++ALE LH+ G++ RD+ N+LLD GH+ LT FG +E
Sbjct: 151 EHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERA 210
Query: 408 PQCCGEAVDNLYSAPEV--GGISELTEACDWWSFGSLLYELLTGMA--------LSQSHP 457
CG Y AP++ GG S +A DWWS G L+YELLTG + SQ+
Sbjct: 211 YSFCGTIE---YMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEI 267
Query: 458 SGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLV 517
S ++ P+ +S A L+ LL +P +RLG G ++K H FF I W L
Sbjct: 268 SRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLA 327
Query: 518 GTSLETHLRTLI 529
+ + +I
Sbjct: 328 AKKVPAPFKPVI 339
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 35/159 (22%)
Query: 364 EMLVALEALHEQGVLCRDLHPGNLLLDQAG---HIRLTYFGQWSEVEPQCCGEAVDNL-- 418
+++ A+ +H+ GV+ RDL P NLL I++ FG ++ ++P DN
Sbjct: 527 KLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFG-FARLKPP------DNQPL 579
Query: 419 --------YSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPE 470
Y+APE+ + E+CD WS G +LY +L+G QSH + + +++ +
Sbjct: 580 KTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMK 639
Query: 471 -------------W--LSRPAASLLTELLQFEPTRRLGM 494
W +S+ A L+ LL +P +RL M
Sbjct: 640 KIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKM 678
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 12/98 (12%)
Query: 113 IFNCHLQRPLSSGASPSA--VQLVQDPATGGTFVVKSLPRCHMVSRERLT--------II 162
I N L + L +GA V+ + TG + +K L + +V + + T ++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 163 PH--GVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
H P++ L F +E + L L+++ GG L++HL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHL 143
>gi|5453976 protein kinase C, theta [Homo sapiens]
Length = 706
Score = 96.3 bits (238), Expect = 6e-20
Identities = 59/176 (33%), Positives = 87/176 (49%), Gaps = 17/176 (9%)
Query: 361 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNL-- 418
+AAE+++ L+ LH +G++ RDL N+LLD+ GHI++ FG E G+A N
Sbjct: 484 YAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKE---NMLGDAKTNTFC 540
Query: 419 ----YSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQ----LPE 470
Y APE+ + + DWWSFG LLYE+L G + H+ P
Sbjct: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR 600
Query: 471 WLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLETHLR 526
WL + A LL +L EP +RLG+ ++ HP F I W +L ++ R
Sbjct: 601 WLEKEAKDLLVKLFVREPEKRLGVR----GDIRQHPLFREINWEELERKEIDPPFR 652
Score = 33.9 bits (76), Expect = 0.39
Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 23/120 (19%)
Query: 92 NKERREA-VKLKITKYLRRAEEIFNCHLQRPLSSGASPSAVQLVQDPATGGTFVVKSLPR 150
NKER +KLKI ++ L + L G S V L + T F +K+L +
Sbjct: 365 NKERPSLQIKLKIEDFI----------LHKMLGKG-SFGKVFLAEFKKTNQFFAIKALKK 413
Query: 151 ----------CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLS 200
C MV + L++ P++T + F +++++F +E++ GG L H+ S
Sbjct: 414 DVVLMDDDVECTMVEKRVLSLAWEH-PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS 472
>gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4
isoform b [Homo sapiens]
Length = 766
Score = 95.5 bits (236), Expect = 1e-19
Identities = 67/194 (34%), Positives = 95/194 (48%), Gaps = 23/194 (11%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQ---- 409
+E +V+ + E+++ALE LH+ G++ RDL N+LLD GHI LT FG E +
Sbjct: 134 KEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKER 193
Query: 410 ---CCGEAVDNLYSAPEVGGISELT---EACDWWSFGSLLYELLTGMA-LSQSHPSGIQA 462
CG Y APE+ I T +A DWWS G LL+ELLTG + + QA
Sbjct: 194 TFSFCGTIE---YMAPEI--IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQA 248
Query: 463 HTQLQL-------PEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSK 515
++ P + A LL LL +P +RLG G G ++++HPFF + W
Sbjct: 249 EVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVA 308
Query: 516 LVGTSLETHLRTLI 529
L + R I
Sbjct: 309 LAARKIPAPFRPQI 322
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 25/162 (15%)
Query: 355 EEQVKQWAAEMLVALEALHEQ-GVLCRDLHPGNLLL--DQAGH-IRLTYFGQWSEVEPQC 410
E + Q ++ A+ +HE+ GV+ RDL P N+L D G +++ FG ++ + PQ
Sbjct: 497 ESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFG-FARLRPQS 555
Query: 411 CGEAVDN-----LYSAPEVGGISELTEACDWWSFGSLLYELLTGMAL--------SQSHP 457
G + Y+APE+ E+CD WS G +LY +L+G QS
Sbjct: 556 PGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQA 615
Query: 458 SGI-----QAHTQLQLPEW--LSRPAASLLTELLQFEPTRRL 492
+ I + L W +S A L+ LL +P +RL
Sbjct: 616 AEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL 657
Score = 29.3 bits (64), Expect = 9.6
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 16/134 (11%)
Query: 90 DPNKERREAVKLKITKYLRRAEE----IFNCHLQRPLSSGASPSA--VQLVQDPATGGTF 143
D + + AV+L+IT+ E + N L + L +GA V+ G +
Sbjct: 3 DEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLY 62
Query: 144 VVKSLPRCHMVSR---------ERLTI-IPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGT 193
+K L + +V R ER + + P++ L F ++ + L L++V GG
Sbjct: 63 AMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGE 122
Query: 194 LWSHLLSQAHSRHS 207
+++HL + + + +
Sbjct: 123 MFTHLYQRQYFKEA 136
>gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4
isoform a [Homo sapiens]
Length = 772
Score = 95.5 bits (236), Expect = 1e-19
Identities = 67/194 (34%), Positives = 95/194 (48%), Gaps = 23/194 (11%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQ---- 409
+E +V+ + E+++ALE LH+ G++ RDL N+LLD GHI LT FG E +
Sbjct: 134 KEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKER 193
Query: 410 ---CCGEAVDNLYSAPEVGGISELT---EACDWWSFGSLLYELLTGMA-LSQSHPSGIQA 462
CG Y APE+ I T +A DWWS G LL+ELLTG + + QA
Sbjct: 194 TFSFCGTIE---YMAPEI--IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQA 248
Query: 463 HTQLQL-------PEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSK 515
++ P + A LL LL +P +RLG G G ++++HPFF + W
Sbjct: 249 EVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVA 308
Query: 516 LVGTSLETHLRTLI 529
L + R I
Sbjct: 309 LAARKIPAPFRPQI 322
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 25/162 (15%)
Query: 355 EEQVKQWAAEMLVALEALHEQ-GVLCRDLHPGNLLL--DQAGH-IRLTYFGQWSEVEPQC 410
E + Q ++ A+ +HE+ GV+ RDL P N+L D G +++ FG ++ + PQ
Sbjct: 503 ESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFG-FARLRPQS 561
Query: 411 CGEAVDN-----LYSAPEVGGISELTEACDWWSFGSLLYELLTGMAL--------SQSHP 457
G + Y+APE+ E+CD WS G +LY +L+G QS
Sbjct: 562 PGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQA 621
Query: 458 SGI-----QAHTQLQLPEW--LSRPAASLLTELLQFEPTRRL 492
+ I + L W +S A L+ LL +P +RL
Sbjct: 622 AEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL 663
Score = 29.3 bits (64), Expect = 9.6
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 16/134 (11%)
Query: 90 DPNKERREAVKLKITKYLRRAEE----IFNCHLQRPLSSGASPSA--VQLVQDPATGGTF 143
D + + AV+L+IT+ E + N L + L +GA V+ G +
Sbjct: 3 DEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLY 62
Query: 144 VVKSLPRCHMVSR---------ERLTI-IPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGT 193
+K L + +V R ER + + P++ L F ++ + L L++V GG
Sbjct: 63 AMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGE 122
Query: 194 LWSHLLSQAHSRHS 207
+++HL + + + +
Sbjct: 123 MFTHLYQRQYFKEA 136
>gi|28557781 protein kinase C, eta [Homo sapiens]
Length = 683
Score = 95.1 bits (235), Expect = 1e-19
Identities = 63/186 (33%), Positives = 92/186 (49%), Gaps = 14/186 (7%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
E + + +AAE++ AL LH++G++ RDL N+LLD GH +L FG E
Sbjct: 453 EARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTA 512
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMA--LSQSHPSGIQA--HT 464
CG Y APE+ A DWW+ G LLYE+L G A +++ +A +
Sbjct: 513 TFCGTPD---YIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILND 569
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLG-MGEGGVSKLKSHPFFSTIQWSKLVGTSLET 523
++ P WL A +L + PT RLG + +GG + HPFF I W++L +E
Sbjct: 570 EVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEP 629
Query: 524 HLRTLI 529
R I
Sbjct: 630 PFRPRI 635
Score = 33.9 bits (76), Expect = 0.39
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 113 IFNCHLQRPLSSGASPSAVQLVQDPATGGTFVVKSLPR----------CHMVSRERLTII 162
I N R L G S V L + TG + VK L + C M + R+ +
Sbjct: 352 IDNFEFIRVLGKG-SFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEK-RILSL 409
Query: 163 PHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
P++T+L F + D +F +E V GG L H+
Sbjct: 410 ARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHI 445
>gi|4502023 AKT2 kinase [Homo sapiens]
Length = 481
Score = 95.1 bits (235), Expect = 1e-19
Identities = 61/177 (34%), Positives = 91/177 (51%), Gaps = 13/177 (7%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
EE+ + + AE++ ALE LH + V+ RD+ NL+LD+ GHI++T FG E
Sbjct: 249 EERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMK 308
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMA--LSQSHPSGIQ--AHT 464
CG Y APEV ++ A DWW G ++YE++ G +Q H +
Sbjct: 309 TFCGTPE---YLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILME 365
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSL 521
+++ P LS A SLL LL+ +P +RLG G ++ H FF +I W +V L
Sbjct: 366 EIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKL 422
Score = 31.2 bits (69), Expect = 2.5
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 8/76 (10%)
Query: 131 VQLVQDPATGGTFVVKSLPRCHMVSRERL--TIIPHGV------PYMTKLLRYFVSEDSI 182
V LV++ ATG + +K L + +++++ + T+ V P++T L F + D +
Sbjct: 166 VILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRL 225
Query: 183 FLHLEHVQGGTLWSHL 198
+E+ GG L+ HL
Sbjct: 226 CFVMEYANGGELFFHL 241
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 95.1 bits (235), Expect = 1e-19
Identities = 58/180 (32%), Positives = 86/180 (47%), Gaps = 15/180 (8%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VE 407
+E Q +AAE+ + L LH++G++ RDL N++LD GHI++ FG E
Sbjct: 436 KEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTT 495
Query: 408 PQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHP-----SGIQA 462
CG Y APE+ ++ DWW++G LLYE+L G I
Sbjct: 496 RTFCGTPD---YIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIME 552
Query: 463 HTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGTSLE 522
H + P+ LS+ A S+ L+ P +RLG G G ++ H FF I W KL ++
Sbjct: 553 H-NVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQ 611
Score = 30.8 bits (68), Expect = 3.3
Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 151 CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
C MV + L ++ P++T+L F + D ++ +E+V GG L H+
Sbjct: 383 CTMVEKRVLALLDKP-PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHI 429
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 95.1 bits (235), Expect = 1e-19
Identities = 60/173 (34%), Positives = 84/173 (48%), Gaps = 13/173 (7%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VE 407
+E +AAE+ + L LH QG++ RDL N++LD GHI++T FG E
Sbjct: 453 KEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTT 512
Query: 408 PQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMAL--SQSHPSGIQA--H 463
CG Y APE+ ++ DWWSFG LLYE+L G + QA
Sbjct: 513 RTFCGTPD---YIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIME 569
Query: 464 TQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
+ P+ LSR A ++ L P +RLG G G +++H FF I W +L
Sbjct: 570 QTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERL 622
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 92.8 bits (229), Expect = 7e-19
Identities = 58/174 (33%), Positives = 85/174 (48%), Gaps = 15/174 (8%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQ-----WSEVEP 408
+E +AAE+ + L L +G++ RDL N++LD GHI++ FG W V
Sbjct: 439 KEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTT 498
Query: 409 QC-CGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHP-----SGIQA 462
+ CG Y APE+ ++ DWW+FG LLYE+L G A + I
Sbjct: 499 KTFCGTPD---YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
Query: 463 HTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
H + P+ +S+ A ++ L+ P +RLG G G +K H FF I W KL
Sbjct: 556 H-NVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKL 608
Score = 33.1 bits (74), Expect = 0.66
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 151 CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
C MV + R+ +P P++T+L F + D ++ +E+V GG L H+
Sbjct: 386 CTMVEK-RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI 432
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 92.8 bits (229), Expect = 7e-19
Identities = 58/174 (33%), Positives = 85/174 (48%), Gaps = 15/174 (8%)
Query: 354 REEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQ-----WSEVEP 408
+E +AAE+ + L L +G++ RDL N++LD GHI++ FG W V
Sbjct: 439 KEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTT 498
Query: 409 QC-CGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHP-----SGIQA 462
+ CG Y APE+ ++ DWW+FG LLYE+L G A + I
Sbjct: 499 KTFCGTPD---YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
Query: 463 HTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKL 516
H + P+ +S+ A ++ L+ P +RLG G G +K H FF I W KL
Sbjct: 556 H-NVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKL 608
Score = 33.1 bits (74), Expect = 0.66
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 151 CHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHL 198
C MV + R+ +P P++T+L F + D ++ +E+V GG L H+
Sbjct: 386 CTMVEK-RVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI 432
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 92.8 bits (229), Expect = 7e-19
Identities = 61/181 (33%), Positives = 93/181 (51%), Gaps = 19/181 (10%)
Query: 349 ATWSVREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFG---QWSE 405
+ + V E+ K + AE+++AL+A+H G++ RD+ P N+LLD+ GH++L FG + E
Sbjct: 182 SNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE 241
Query: 406 VEPQCCGEAVDNL-YSAPEV----GGISELTEACDWWSFGSLLYELLTG------MALSQ 454
C AV Y +PEV GG CDWWS G LYE+L G +L
Sbjct: 242 TGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVG 301
Query: 455 SHPSGIQAHTQLQLPE--WLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQ 512
++ + L PE +S+ A +L+ L R + +G GV +++ HPFF Q
Sbjct: 302 TYSKIMDHKNSLCFPEDAEISKHAKNLICAFL---TDREVRLGRNGVEEIRQHPFFKNDQ 358
Query: 513 W 513
W
Sbjct: 359 W 359
>gi|75709228 protein kinase C, zeta isoform 2 [Homo sapiens]
Length = 409
Score = 92.4 bits (228), Expect = 9e-19
Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 21/180 (11%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
EE + +AAE+ +AL LHE+G++ RDL N+LLD GHI+LT +G E
Sbjct: 167 EEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS 226
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQ--- 465
CG Y APE+ E + DWW+ G L++E++ G + +T+
Sbjct: 227 TFCGTP---NYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYL 283
Query: 466 --------LQLPEWLSRPAASLLTELLQFEPTRRLG-MGEGGVSKLKSHPFFSTIQWSKL 516
+++P +LS A+ +L L +P RLG + G S +KSH FF +I W L
Sbjct: 284 FQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 343
>gi|75709226 protein kinase C, zeta isoform 2 [Homo sapiens]
Length = 409
Score = 92.4 bits (228), Expect = 9e-19
Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 21/180 (11%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
EE + +AAE+ +AL LHE+G++ RDL N+LLD GHI+LT +G E
Sbjct: 167 EEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS 226
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQ--- 465
CG Y APE+ E + DWW+ G L++E++ G + +T+
Sbjct: 227 TFCGTP---NYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYL 283
Query: 466 --------LQLPEWLSRPAASLLTELLQFEPTRRLG-MGEGGVSKLKSHPFFSTIQWSKL 516
+++P +LS A+ +L L +P RLG + G S +KSH FF +I W L
Sbjct: 284 FQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 343
>gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens]
Length = 592
Score = 92.4 bits (228), Expect = 9e-19
Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 21/180 (11%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
EE + +AAE+ +AL LHE+G++ RDL N+LLD GHI+LT +G E
Sbjct: 350 EEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS 409
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQ--- 465
CG Y APE+ E + DWW+ G L++E++ G + +T+
Sbjct: 410 TFCGTP---NYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYL 466
Query: 466 --------LQLPEWLSRPAASLLTELLQFEPTRRLG-MGEGGVSKLKSHPFFSTIQWSKL 516
+++P +LS A+ +L L +P RLG + G S +KSH FF +I W L
Sbjct: 467 FQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 526
>gi|4885563 protein kinase C, epsilon [Homo sapiens]
Length = 737
Score = 92.4 bits (228), Expect = 9e-19
Identities = 59/171 (34%), Positives = 82/171 (47%), Gaps = 15/171 (8%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
E + + +AAE+ AL LH+ GV+ RDL N+LLD GH +L FG E
Sbjct: 506 EPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTT 565
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGM----ALSQSHPSGIQAHT 464
CG Y APE+ E + DWW+ G L+YE++ G A ++ H
Sbjct: 566 TFCGTPD---YIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHD 622
Query: 465 QLQLPEWLSRPAASLLTELLQFEPTRRLG--MGEGGVSKLKSHPFFSTIQW 513
+ P WLS+ A S+L + P +RLG + G +K HPFF I W
Sbjct: 623 DVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDW 673
Score = 30.8 bits (68), Expect = 3.3
Identities = 13/41 (31%), Positives = 25/41 (60%)
Query: 154 VSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTL 194
++ +R+ + PY+T+L F ++D +F +E+V GG L
Sbjct: 454 MTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDL 494
>gi|133908623 protein kinase C, iota [Homo sapiens]
Length = 596
Score = 91.3 bits (225), Expect = 2e-18
Identities = 58/182 (31%), Positives = 91/182 (50%), Gaps = 23/182 (12%)
Query: 355 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSE------VEP 408
EE + ++AE+ +AL LHE+G++ RDL N+LLD GHI+LT +G E
Sbjct: 352 EEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTS 411
Query: 409 QCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG-----MALSQSHPS----- 458
CG Y APE+ + + DWW+ G L++E++ G + S +P
Sbjct: 412 TFCGTP---NYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTED 468
Query: 459 ---GIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGM-GEGGVSKLKSHPFFSTIQWS 514
+ Q+++P LS AAS+L L +P RLG + G + ++ HPFF + W
Sbjct: 469 YLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWD 528
Query: 515 KL 516
+
Sbjct: 529 MM 530
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,640,485
Number of Sequences: 37866
Number of extensions: 1284601
Number of successful extensions: 5723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 4480
Number of HSP's gapped (non-prelim): 1043
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.