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Search of human proteins with 13676857
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 1261 0.0
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 1109 0.0
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 1070 0.0
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 1070 0.0
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 1050 0.0
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 1012 0.0
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 838 0.0
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 785 0.0
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 573 e-163
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 321 1e-87
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 276 4e-74
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 271 2e-72
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 258 1e-68
gi|42544159 heat shock 105kD [Homo sapiens] 255 8e-68
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 215 1e-55
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 215 1e-55
gi|38348298 ankyrin repeat domain 45 [Homo sapiens] 46 1e-04
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 40 0.005
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 40 0.005
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 40 0.007
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 40 0.007
gi|9910266 kinesin family member 15 [Homo sapiens] 37 0.073
gi|24497501 forkhead box A1 [Homo sapiens] 36 0.095
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 36 0.095
gi|119395750 keratin 1 [Homo sapiens] 36 0.12
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 36 0.12
gi|119220564 one cut domain, family member 2 [Homo sapiens] 35 0.16
gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens] 35 0.16
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 35 0.21
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 35 0.21
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 1261 bits (3264), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV 60
MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV
Sbjct: 1 MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV 60
Query: 61 AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI 120
AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI
Sbjct: 61 AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI 120
Query: 121 SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA 180
SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA
Sbjct: 121 SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA 180
Query: 181 AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM 240
AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM
Sbjct: 181 AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM 240
Query: 241 VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI 300
VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI
Sbjct: 241 VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI 300
Query: 301 TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK 360
TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK
Sbjct: 301 TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK 360
Query: 361 ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN 420
ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN
Sbjct: 361 ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN 420
Query: 421 TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT 480
TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT
Sbjct: 421 TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT 480
Query: 481 FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA 540
FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA
Sbjct: 481 FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA 540
Query: 541 AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK 600
AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK
Sbjct: 541 AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK 600
Query: 601 ELERVCNPIISKLYQGGPGGGSGGGGSGASGGPTIEEVD 639
ELERVCNPIISKLYQGGPGGGSGGGGSGASGGPTIEEVD
Sbjct: 601 ELERVCNPIISKLYQGGPGGGSGGGGSGASGGPTIEEVD 639
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 1109 bits (2868), Expect = 0.0
Identities = 558/647 (86%), Positives = 601/647 (92%), Gaps = 12/647 (1%)
Query: 3 ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62
++GPA+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 2 SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
NPTNT+FDAKRLIGR+F+DA VQSDMKHWPF VV++ G+PKVQVEYKGETK+F+PEE+SS
Sbjct: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
MVLTKMKEIAEAYLG V +AV+TVPAYFNDSQRQATKDAGTI GLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLDKK G E+NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV+
Sbjct: 182 AYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVN 239
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
H EFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEG+DFYTSITR
Sbjct: 240 HFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITR 299
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
ARFEELNADLFRGTL+PVEKALRDAKLDK QI +IVLVGGSTRIPKIQKLLQDFFNGKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
NKSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDVTPLSLGIETAGGVMT LIKRNTT
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTT 419
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482
IPTKQTQTFTTYSDNQ VL+QVYEGERAMTKDNNLLGKF+LTGIPPAPRGVPQIEVTFD
Sbjct: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFD 479
Query: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542
IDANGILNV+A DKSTGKENKITITNDKGRLSK+DI+RMVQEAE+YK+EDE RD+V++K
Sbjct: 480 IDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSK 539
Query: 543 NALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKEL 602
N+LESY +N+K TVEDEKL+GKI+++DK KILDKC E+INWLD+NQ AEK+E+EH+QKEL
Sbjct: 540 NSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKEL 599
Query: 603 ERVCNPIISKLYQ-------GGPGGGSGGG---GSGASGGPTIEEVD 639
E+VCNPII+KLYQ G PGG GGG GAS GPTIEEVD
Sbjct: 600 EKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 1070 bits (2767), Expect = 0.0
Identities = 537/642 (83%), Positives = 586/642 (91%), Gaps = 7/642 (1%)
Query: 3 ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62
A+ AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 2 AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
NP NT+FDAKRLIGRKF D VQSDMKHWPF+V+++G KPKVQV YKGETK F+PEEISS
Sbjct: 62 NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
MVLTKMKEIAEAYLG V +AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLD+ G GE+NVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+
Sbjct: 182 AYGLDRTG--KGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
H EEFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EG+DFYTSITR
Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITR 299
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
ARFEEL +DLFR TLEPVEKALRDAKLDK QI ++VLVGGSTRIPK+QKLLQDFFNG++L
Sbjct: 300 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDL 359
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
NKSINPDEAVAYGAAVQAAIL+GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+T
Sbjct: 360 NKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNST 419
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482
IPTKQTQ FTTYSDNQ VL+QVYEGERAMTKDNNLLG+F+L+GIPPAPRGVPQIEVTFD
Sbjct: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFD 479
Query: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542
IDANGILNVTA DKSTGK NKITITNDKGRLSK++I+RMVQEAE+YK+EDE R+RV+AK
Sbjct: 480 IDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAK 539
Query: 543 NALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKEL 602
NALESY +N+K VEDE L+GKISE DK K+LDKCQEVI+WLD N +AEKDE+EHK+KEL
Sbjct: 540 NALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKEL 599
Query: 603 ERVCNPIISKLYQGGPGGGSGGGGS-----GASGGPTIEEVD 639
E+VCNPIIS LYQG G G GG G+ G+ GPTIEEVD
Sbjct: 600 EQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 1070 bits (2767), Expect = 0.0
Identities = 537/642 (83%), Positives = 586/642 (91%), Gaps = 7/642 (1%)
Query: 3 ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62
A+ AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 2 AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
NP NT+FDAKRLIGRKF D VQSDMKHWPF+V+++G KPKVQV YKGETK F+PEEISS
Sbjct: 62 NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
MVLTKMKEIAEAYLG V +AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLD+ G GE+NVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+
Sbjct: 182 AYGLDRTG--KGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
H EEFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EG+DFYTSITR
Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITR 299
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
ARFEEL +DLFR TLEPVEKALRDAKLDK QI ++VLVGGSTRIPK+QKLLQDFFNG++L
Sbjct: 300 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDL 359
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
NKSINPDEAVAYGAAVQAAIL+GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+T
Sbjct: 360 NKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNST 419
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482
IPTKQTQ FTTYSDNQ VL+QVYEGERAMTKDNNLLG+F+L+GIPPAPRGVPQIEVTFD
Sbjct: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFD 479
Query: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542
IDANGILNVTA DKSTGK NKITITNDKGRLSK++I+RMVQEAE+YK+EDE R+RV+AK
Sbjct: 480 IDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAK 539
Query: 543 NALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKEL 602
NALESY +N+K VEDE L+GKISE DK K+LDKCQEVI+WLD N +AEKDE+EHK+KEL
Sbjct: 540 NALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKEL 599
Query: 603 ERVCNPIISKLYQGGPGGGSGGGGS-----GASGGPTIEEVD 639
E+VCNPIIS LYQG G G GG G+ G+ GPTIEEVD
Sbjct: 600 EQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 1050 bits (2714), Expect = 0.0
Identities = 526/641 (82%), Positives = 583/641 (90%), Gaps = 5/641 (0%)
Query: 2 SARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 61
+A+G AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 3 TAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 62
Query: 62 MNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEIS 121
MNP NT+FDAKRLIGRKF D VQ+DMK WPF+V++EGGKPKV V YKGE K F+PEEIS
Sbjct: 63 MNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEIS 122
Query: 122 SMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAA 181
SMVLTK+KE AEA+LG V +AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAA
Sbjct: 123 SMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 182
Query: 182 IAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV 241
IAYGLDK G GE++VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V
Sbjct: 183 IAYGLDKGG--QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240
Query: 242 SHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSIT 301
SH EEFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEG+DFYTSIT
Sbjct: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300
Query: 302 RARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKE 361
RARFEEL ADLFRGTLEPVEKALRDAK+DK +I +IVLVGGSTRIPK+Q+LLQD+FNG++
Sbjct: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360
Query: 362 LNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNT 421
LNKSINPDEAVAYGAAVQAAIL+GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+
Sbjct: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420
Query: 422 TIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTF 481
TIPTKQTQ FTTYSDNQ VL+QVYEGERAMTKDNNLLG+FDLTGIPPAPRGVPQIEVTF
Sbjct: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480
Query: 482 DIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAA 541
DIDANGILNVTA DKSTGK NKITITNDKGRLSK++I+RMV +AE+YK+EDE R+++AA
Sbjct: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540
Query: 542 KNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 601
KNALESY +N+K V DE L+GKISE DKNKILDKC E+++WL+ NQ+AEKDE++HK+KE
Sbjct: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600
Query: 602 LERVCNPIISKLYQG---GPGGGSGGGGSGASGGPTIEEVD 639
LE++CNPII+KLYQG GP G+G + GPTIEEVD
Sbjct: 601 LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD 641
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 1012 bits (2617), Expect = 0.0
Identities = 503/639 (78%), Positives = 574/639 (89%), Gaps = 9/639 (1%)
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLT 126
T+FDAKRLIGRKF D TVQSDMKHWPFRVVSEGGKPKV+V Y+GE KTF+PEEISSMVL+
Sbjct: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
KMKE AEAYLG V AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAAIAYGL
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 187 DKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAE 246
D++G GE+NVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+V+H E
Sbjct: 188 DRRGA--GERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFME 245
Query: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
EF+RKH KD+ NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EGVDFYTSITRARFE
Sbjct: 246 EFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFE 305
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
EL +DLFR TLEPVEKALRDAKLDK QI ++VLVGGSTRIPK+QKLLQDFFNGKELNKSI
Sbjct: 306 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSI 365
Query: 367 NPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTK 426
NPDEAVAYGAAVQAA+L+GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTK
Sbjct: 366 NPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTK 425
Query: 427 QTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDAN 486
QTQTFTTYSDNQ V +QVYEGERAMTKDNNLLG+F+L+GIPPAPRGVPQIEVTFDIDAN
Sbjct: 426 QTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDAN 485
Query: 487 GILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALE 546
GIL+VTA D+STGK NKITITNDKGRLSK++++RMV EAE+YK+EDEA RDRVAAKN+LE
Sbjct: 486 GILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLE 545
Query: 547 SYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVC 606
++ +++K ++++E LR KI E+D+ K+ DKC+EV+ WL+ NQ+AEK+EYEH+++ELE++C
Sbjct: 546 AHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQIC 605
Query: 607 NPIISKLYQGGPG--GGSGGGGSGASG----GPTIEEVD 639
PI S+LY GGPG GGS G G GP IEEVD
Sbjct: 606 RPIFSRLY-GGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 838 bits (2166), Expect = 0.0
Identities = 425/474 (89%), Positives = 447/474 (94%), Gaps = 3/474 (0%)
Query: 3 ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62
++GPA+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 2 SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
NPTNT+FDAKRLIGR+F+DA VQSDMKHWPF VV++ G+PKVQVEYKGETK+F+PEE+SS
Sbjct: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
MVLTKMKEIAEAYLG V +AV+TVPAYFNDSQRQATKDAGTI GLNVLRIINEPTAAAI
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLDKK G E+NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV+
Sbjct: 182 AYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVN 239
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
H EFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEG+DFYTSITR
Sbjct: 240 HFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITR 299
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
ARFEELNADLFRGTL+PVEKALRDAKLDK QI +IVLVGGSTRIPKIQKLLQDFFNGKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
NKSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDVTPLSLGIETAGGVMT LIKRNTT
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTT 419
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPA-PRGVP 475
IPTKQTQTFTTYSDNQ VL+QVYEGERAMTKDNNLLGKF+LTG+P P G P
Sbjct: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
Score = 34.7 bits (78), Expect = 0.28
Identities = 18/27 (66%), Positives = 18/27 (66%), Gaps = 3/27 (11%)
Query: 616 GGPGGGSGGGG---SGASGGPTIEEVD 639
G PGG GGG GAS GPTIEEVD
Sbjct: 467 GMPGGFPGGGAPPSGGASSGPTIEEVD 493
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 785 bits (2028), Expect = 0.0
Identities = 400/618 (64%), Positives = 496/618 (80%), Gaps = 9/618 (1%)
Query: 5 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 63
G +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+ N
Sbjct: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
Query: 64 PTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKG-ETKTFFPEEISS 122
P NT+FDAKRLIGR + D +VQ D+K PF+VV + KP +QV+ G +TKTF PEEIS+
Sbjct: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
MVLTKMKE AEAYLG KV AV+TVPAYFND+QRQATKDAGTI GLNV+RIINEPTAAAI
Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLDK+ GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++
Sbjct: 208 AYGLDKRE---GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
H + +K+K KD+ + RAV++LR E+AKR LSS QA IEI+S YEG DF ++TR
Sbjct: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTR 324
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
A+FEELN DLFR T++PV+K L D+ L K I EIVLVGGSTRIPKIQ+L+++FFNGKE
Sbjct: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
++ INPDEAVAYGAAVQA +L GD ++ DL+LLDV PL+LGIET GGVMT LI RNT
Sbjct: 385 SRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTV 442
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482
+PTK++Q F+T SDNQ +V ++VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+
Sbjct: 443 VPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFE 502
Query: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542
ID NGIL VTA DK TG +NKITITND+ RL+ ++I+RMV +AE++ ED+ ++R+ +
Sbjct: 503 IDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTR 562
Query: 543 NALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 601
N LESY Y++K + D EKL GK+S +DK + +E I WL+ +Q A+ ++++ K+KE
Sbjct: 563 NELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKE 622
Query: 602 LERVCNPIISKLY-QGGP 618
LE + PIISKLY GP
Sbjct: 623 LEEIVQPIISKLYGSAGP 640
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 573 bits (1476), Expect = e-163
Identities = 313/630 (49%), Positives = 416/630 (66%), Gaps = 20/630 (3%)
Query: 4 RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62
+G +GIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q
Sbjct: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
NP NT + KRLIGR+++D VQ D+K+ PF++V VE G K + P +I +
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG--KLYSPSQIGA 168
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
VL KMKE AE YLG +AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
AYGLDK +K + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD ++
Sbjct: 229 AYGLDKSE----DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284
Query: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVD----FYT 298
H+ +EFKR+ D+ + A++R+R A E+AK LSSS Q I + L
Sbjct: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344
Query: 299 SITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFN 358
+TRA+FE + DL R T+ P +KA++DA++ K I E++LVGG TR+PK+Q+ +QD F
Sbjct: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403
Query: 359 GKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIK 418
G+ +K++NPDEAVA GAA+Q +L GD V D+LLLDVTPLSLGIET GGV T LI
Sbjct: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459
Query: 419 RNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIE 478
RNTTIPTK++Q F+T +D Q+ V ++V +GER M DN LLG+F L GIPPAPRGVPQIE
Sbjct: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519
Query: 479 VTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDR 538
VTFDIDANGI++V+A DK TG+E +I I G LSKDDI+ MV+ AE+Y ED ++R
Sbjct: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578
Query: 539 VAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHK 598
V A N E ++ + +E+ + ++ + NK+ ++ ++ L R +
Sbjct: 579 VEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIRQA 636
Query: 599 QKELERVCNPIISKLYQGGPGGGSGGGGSG 628
L++ + Y+ G G SG
Sbjct: 637 ASSLQQASLKLFEMAYKKMASEREGSGSSG 666
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 321 bits (822), Expect = 1e-87
Identities = 180/505 (35%), Positives = 289/505 (57%), Gaps = 7/505 (1%)
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
AIG+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N +N
Sbjct: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLT 126
T+ K+++GR D Q + V+ + GK + +++ ETK PE+++ ++ +
Sbjct: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
Query: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
KMKE A + LG + VITVP F + Q+ A +A G NVLR+I+EP+AA +AYG+
Sbjct: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
Query: 187 DKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAE 246
+ G + N+L+F LGG + +S++ + GI+ V ST D ++GG F + +LA
Sbjct: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
Query: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSLYEG DF +++RARFE
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
L + LF +E + L I ++VL GGS+RIPK+Q+L++D F EL SI
Sbjct: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
Query: 367 NPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTPLIKRNTT 422
PDE + GAA++A ILIG ++ V+D L+++ + L G++ +G T L T
Sbjct: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
Query: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGE-RAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTF 481
+P ++ T + SSV +++YE + + K+ + L + G+ I
Sbjct: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
Query: 482 DIDANGILNVTAADKSTGKENKITI 506
+ +G L+VT D+ TGK I+I
Sbjct: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 276 bits (706), Expect = 4e-74
Identities = 168/420 (40%), Positives = 247/420 (58%), Gaps = 52/420 (12%)
Query: 8 IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 65
IGIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NP
Sbjct: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
Query: 66 NTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVL 125
NTI+DAKR IG+ F +++++ +PF+V+++ G + V ET T PE + S +L
Sbjct: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
Query: 126 TKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYG 185
K+KE+AEAYLG V +AVI+VPA F+ QR +T +A + GL +LR+INEPTAAA+AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
Query: 186 LDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLA 245
L K +VL+ DLGGGT DVS+L + G+F ++ +G+ LGG+DF+ R++ +L
Sbjct: 213 LHKADVF----HVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLY 268
Query: 246 EEFKRKHKKDIGPNKRAVRRLRTACERAK--RTLSSSTQASIEI---------------- 287
++ + + + K + RLR A E K TL S Q S+ +
Sbjct: 269 KQIYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTE 327
Query: 288 ---DSLYEGVD----------------------FYTSITRARFEELNADLFRGTLEPVEK 322
D L D F T I+R F+ LN DLF+ L P+++
Sbjct: 328 LPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQ 387
Query: 323 ALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAI 382
L++ L+K +I E+VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV G A+QA I
Sbjct: 388 VLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 271 bits (692), Expect = 2e-72
Identities = 179/580 (30%), Positives = 298/580 (51%), Gaps = 25/580 (4%)
Query: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67
+GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT
Sbjct: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
Query: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126
+ KR GR F D V+++ + + +V G ++V Y E + F E++++M+L+
Sbjct: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
Query: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
K+KE AE+ L V V++VP ++ D++R++ DA I GLN LR++NE TA A+AYG+
Sbjct: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
Query: 187 DKKGCAGGE---KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243
K+ E +NV+ D+G + VS+ G +V +TA DT LGG FD +V+H
Sbjct: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
Query: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGVDFYTSITR 302
EEF +K+K DI RA+ RL CE+ K+ +S +++ + I+ VD ++ R
Sbjct: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
+F E+ DL P+ L KL K I + +VGG+TRIP +++ + FF GKEL
Sbjct: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTPLI 417
+ ++N DEAV G A+Q AIL + V++ + DV P + + G +
Sbjct: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
Query: 418 KRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VPQ 476
+N P + TF + L Y + + + + +F + + P G +
Sbjct: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
Query: 477 IEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDE 533
++V ++ +GI +V++A + +EN+ + D+ +K++ V + E + E +
Sbjct: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEEQQ 535
Query: 534 ANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKI 573
+ A+N ES Q +K + + K K+
Sbjct: 536 ---QQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKN 571
++ ++ ++ ++ + +D+ ++R AKNA+E Y Y ++ + E +SE D+N
Sbjct: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGE-YEKFVSEDDRN 646
Query: 572 KILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609
K ++ NWL + + K Y K EL+ + PI
Sbjct: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 258 bits (659), Expect = 1e-68
Identities = 166/563 (29%), Positives = 288/563 (51%), Gaps = 28/563 (4%)
Query: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67
+GIDLG + V + G +E IAN+ +R TP+ ++ R IG+AAK+Q+ N NT
Sbjct: 4 VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNT 63
Query: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126
I K+L GR F+D VQ++ P+ + G V+V Y E + F E+++ M+L
Sbjct: 64 IHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLA 123
Query: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
K+KE +E L V VI++P++F D++R++ A + GLN LR++NE TA A+AYG+
Sbjct: 124 KLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183
Query: 187 DKKGCAGGE---KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243
K+ + +NV+ D+G + V + G +V +T D +LGG +FD +V +
Sbjct: 184 YKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDY 243
Query: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGVDFYTSITR 302
+EFK K+K ++ N RA+ RL CE+ K+ +S +++ + I+ +D + + R
Sbjct: 244 FCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNR 303
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
A+FE+L A L P++ + A L + I I +VGG+TRIP +++ + FF K++
Sbjct: 304 AQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-KDI 362
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTPLI 417
+ ++N DEAVA G A+Q AIL + V++ + D+ P S+ + G +
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420
Query: 418 KRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VPQ 476
+N P + TF + L Y + + +G F + + P G +
Sbjct: 421 CKNHPAPFSKVITF---HKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSK 477
Query: 477 IEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANR 536
++V ++ +GI +V +A +K L D D ++ +K+E++ N
Sbjct: 478 VKVKVRVNIHGIFSVASAS-----------VIEKQNLEGDHSDAPMETETSFKNENKDNM 526
Query: 537 DRVAAKNALESYTYNIKQTVEDE 559
D++ + + T E+E
Sbjct: 527 DKMQVDQEEGHQKCHAEHTPEEE 549
Score = 39.7 bits (91), Expect = 0.009
Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVED--EKLRGKISEQD 569
+L +D ++ ++ + +D+ ++R AKNA+E Y Y+ + + EK I+ +D
Sbjct: 591 QLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKF---ITPED 647
Query: 570 KNKILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPIISK 612
+K+ ++ NWL + + K Y K +EL++ PI K
Sbjct: 648 LSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMK 691
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 255 bits (652), Expect = 8e-68
Identities = 171/537 (31%), Positives = 280/537 (52%), Gaps = 27/537 (5%)
Query: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67
+G+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
Query: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126
+ + KR GR F D +Q + ++ + +V + G ++V Y GE F E+I++M+LT
Sbjct: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
Query: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
K+KE AE L V VI+VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
Query: 187 DKKGCAGGEKN---VLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243
K+ ++ V+ D+G F VS G +V TA D LGG++FD ++V H
Sbjct: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
Query: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGVDFYTSITR 302
EFK K+K D RA+ RL CE+ K+ +SS ST + I+ D + R
Sbjct: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
Query: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
++FEEL A+L + P+ L L + + +VGG+TRIP +++ + FF GK++
Sbjct: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
Query: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTPL 416
+ ++N DEAVA G A+Q AIL + V++ + D P + + E GV +
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419
Query: 417 IKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VP 475
RN P + TF + L Y + + +G+F + + G
Sbjct: 420 FSRNHAAPFSKVLTFLRRGPFE---LEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
Query: 476 QIEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSK-----DDIDRMVQE 524
+++V ++ +GI ++ A +K +EN+++ D L++ D D+ VQ+
Sbjct: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQ 533
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGK----ISE 567
+L KD ++ ++ + +D+ ++R AKNA+E Y Y + +KL G I E
Sbjct: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFR-----DKLCGPYEKFICE 659
Query: 568 QDKNKILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609
QD L E +WL + + K Y K +EL ++ P+
Sbjct: 660 QDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702
Score = 30.8 bits (68), Expect = 4.0
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 13/68 (19%)
Query: 557 EDEKLRGKISEQDKNKILDKCQEVINW------------LDRNQMAEKDEYEHKQKELER 604
+DEK I E + K+ EV+ W LD++ + E + K KEL
Sbjct: 736 KDEKYN-HIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNN 794
Query: 605 VCNPIISK 612
C P++++
Sbjct: 795 TCEPVVTQ 802
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 215 bits (547), Expect = 1e-55
Identities = 159/546 (29%), Positives = 274/546 (50%), Gaps = 54/546 (9%)
Query: 8 IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWP-FRVVSEGGKPKVQVEYKGETKTFFPEEISSMVL 125
T+ + L+G++ ++ V +P + + + V + + + F PEE+ MVL
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
Query: 126 TKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYG 185
+ +AE + + AVITVP +FN ++R+A A + GL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
Query: 186 L-DKKGCAGGEKNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 235
+ +K +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
Query: 236 FDNRMVSHLAEEFKRKHK----KDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 291
+ R+ LA F + K KD+ N RA+ +L R K LS++ +I+ L
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
Query: 292 EGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQK 351
+ VDF +TR FEEL ADLF PV++AL+ A++ +I++++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
Query: 352 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLD--VTPLSL----- 404
+L +EL K+IN DEA A GA QAA L K+ V+ ++ D V P+ +
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTRE 452
Query: 405 -----GIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAM--TKDNN 457
GI + L R P ++ TF YS + + + G+ +D
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFN---FHINYGDLGFLGPEDLR 509
Query: 458 LLGKFDLT-----GIPPAPRGVPQ-----IEVTFDIDANGILNV--------TAADKSTG 499
+ G +LT G+ + + P I+ F++D +G+L++ T + S
Sbjct: 510 VFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAE 569
Query: 500 KENKIT 505
+E+ +T
Sbjct: 570 EESTLT 575
Score = 34.3 bits (77), Expect = 0.36
Identities = 50/266 (18%), Positives = 99/266 (37%), Gaps = 31/266 (11%)
Query: 379 QAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQ 438
++ +L D+ E+V + L+ D + G ++ L TT K+ T T + +
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 439 SSVLVQVYE-GERAMTKDNNLLGKFDLTGIPPA-PRG--VPQIEVTFDID---------- 484
S E GE+ K+ D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKP 666
Query: 485 -------ANGILNVTAADKSTGKENKITITNDKG---------RLSKDDIDRMVQEAERY 528
G+ +K K + + G L +D + + VQ+ +
Sbjct: 667 SEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDL 726
Query: 529 KSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL-DRN 587
D ++R A N+LE++ + + + + + +E+ + +I K WL D
Sbjct: 727 TLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEG 786
Query: 588 QMAEKDEYEHKQKELERVCNPIISKL 613
A + K EL ++C + ++
Sbjct: 787 VGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 215 bits (547), Expect = 1e-55
Identities = 159/546 (29%), Positives = 274/546 (50%), Gaps = 54/546 (9%)
Query: 8 IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWP-FRVVSEGGKPKVQVEYKGETKTFFPEEISSMVL 125
T+ + L+G++ ++ V +P + + + V + + + F PEE+ MVL
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
Query: 126 TKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYG 185
+ +AE + + AVITVP +FN ++R+A A + GL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
Query: 186 L-DKKGCAGGEKNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 235
+ +K +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
Query: 236 FDNRMVSHLAEEFKRKHK----KDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 291
+ R+ LA F + K KD+ N RA+ +L R K LS++ +I+ L
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
Query: 292 EGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQK 351
+ VDF +TR FEEL ADLF PV++AL+ A++ +I++++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
Query: 352 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLD--VTPLSL----- 404
+L +EL K+IN DEA A GA QAA L K+ V+ ++ D V P+ +
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTRE 452
Query: 405 -----GIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAM--TKDNN 457
GI + L R P ++ TF YS + + + G+ +D
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFN---FHINYGDLGFLGPEDLR 509
Query: 458 LLGKFDLT-----GIPPAPRGVPQ-----IEVTFDIDANGILNV--------TAADKSTG 499
+ G +LT G+ + + P I+ F++D +G+L++ T + S
Sbjct: 510 VFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAE 569
Query: 500 KENKIT 505
+E+ +T
Sbjct: 570 EESTLT 575
Score = 34.3 bits (77), Expect = 0.36
Identities = 50/266 (18%), Positives = 99/266 (37%), Gaps = 31/266 (11%)
Query: 379 QAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQ 438
++ +L D+ E+V + L+ D + G ++ L TT K+ T T + +
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 439 SSVLVQVYE-GERAMTKDNNLLGKFDLTGIPPA-PRG--VPQIEVTFDID---------- 484
S E GE+ K+ D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKP 666
Query: 485 -------ANGILNVTAADKSTGKENKITITNDKG---------RLSKDDIDRMVQEAERY 528
G+ +K K + + G L +D + + VQ+ +
Sbjct: 667 SEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDL 726
Query: 529 KSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL-DRN 587
D ++R A N+LE++ + + + + + +E+ + +I K WL D
Sbjct: 727 TLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEG 786
Query: 588 QMAEKDEYEHKQKELERVCNPIISKL 613
A + K EL ++C + ++
Sbjct: 787 VGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
Length = 266
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 537 DRVAAKNALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEY 595
D A+ L+ Y + V D EK GK+ ++DKN IL C+ WL+ + A +E
Sbjct: 163 DWADARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINEL 222
Query: 596 EHKQKELERVCNPIISKL 613
++++LE + PI +K+
Sbjct: 223 FEQRQQLEDIVTPIFTKM 240
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.005
Identities = 17/41 (41%), Positives = 24/41 (58%)
Query: 592 KDEYEHKQKELERVCNPIISKLYQGGPGGGSGGGGSGASGG 632
++E E +++E E + + L GG GGG GGGG G GG
Sbjct: 37 EEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
Score = 31.2 bits (69), Expect = 3.1
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 591 EKDEYEHKQKELERVCNPIISKLYQGGPGGGSGGGGSG 628
E++E E ++ E E V +++ GG GGG GG G G
Sbjct: 40 EEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 40.4 bits (93), Expect = 0.005
Identities = 17/41 (41%), Positives = 24/41 (58%)
Query: 592 KDEYEHKQKELERVCNPIISKLYQGGPGGGSGGGGSGASGG 632
++E E +++E E + + L GG GGG GGGG G GG
Sbjct: 37 EEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
Score = 31.2 bits (69), Expect = 3.1
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 591 EKDEYEHKQKELERVCNPIISKLYQGGPGGGSGGGGSG 628
E++E E ++ E E V +++ GG GGG GG G G
Sbjct: 40 EEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Query: 496 KSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSED-EANRDRVAAKNALESYTYNIKQ 554
+S +E + + + R + D ++E ER K +D E R+R + + N +
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 417
Query: 555 TVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELER 604
E EK R K E+D+ + +K E DR++ EK++ + K++E +R
Sbjct: 418 DKEREKDREKDKEKDREREREKEHE----KDRDKEKEKEQDKEKEREKDR 463
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Query: 496 KSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSED-EANRDRVAAKNALESYTYNIKQ 554
+S +E + + + R + D ++E ER K +D E R+R + + N +
Sbjct: 242 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 301
Query: 555 TVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELER 604
E EK R K E+D+ + +K E DR++ EK++ + K++E +R
Sbjct: 302 DKEREKDREKDKEKDREREREKEHE----KDRDKEKEKEQDKEKEREKDR 347
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 36.6 bits (83), Expect = 0.073
Identities = 59/332 (17%), Positives = 141/332 (42%), Gaps = 26/332 (7%)
Query: 276 TLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQ 335
+L + + ++ D L E V + FE ++ +L T++ AL+ AKLD+ + +
Sbjct: 685 SLYTQNSSILDNDILNEPVP--PEMNEQAFEAISEEL--RTVQEQMSALQ-AKLDEEEHK 739
Query: 336 EIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLL 395
+ L ++ +Q+ F+ + ++ + +E ++ ++ + +++ D L
Sbjct: 740 NLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQL---QETQTKNDFL 796
Query: 396 LLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQV----YEGERA 451
+V L + + +A ++ + ++ T Q + F S+ V +Q+ E E+
Sbjct: 797 KSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKL 856
Query: 452 MTKD-------NNL--LGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKEN 502
+ +NL + KF++ + + + T D N ++ + A+K +
Sbjct: 857 LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL 916
Query: 503 KITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLR 562
+ DK SK +I ++++ + K ++ A ++ AK ++ ++ T +
Sbjct: 917 SLQFEEDKENSSK-EILKVLEAVRQEKQKETAKCEQQMAK--VQKLEESLLATEKVISSL 973
Query: 563 GKISEQDKNKILDKCQEVINWLDRNQMAEKDE 594
K + DK + D ++ R + EK E
Sbjct: 974 EKSRDSDKKVVADLMNQIQEL--RTSVCEKTE 1003
>gi|24497501 forkhead box A1 [Homo sapiens]
Length = 472
Score = 36.2 bits (82), Expect = 0.095
Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 585 DRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGGSGGGGSGASGGP 633
D M E Y +QK + P G GGGSG GGSGA GGP
Sbjct: 249 DSGNMFENGCYLRRQKRFKCEKQP------GAGGGGGSGSGGSGAKGGP 291
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 36.2 bits (82), Expect = 0.095
Identities = 14/21 (66%), Positives = 15/21 (71%)
Query: 617 GPGGGSGGGGSGASGGPTIEE 637
GPGGG GGGG G GGP E+
Sbjct: 75 GPGGGGGGGGGGGGGGPGHEQ 95
Score = 30.0 bits (66), Expect = 6.8
Identities = 13/21 (61%), Positives = 13/21 (61%)
Query: 611 SKLYQGGPGGGSGGGGSGASG 631
S L GG GGG GGGG G G
Sbjct: 72 SALGPGGGGGGGGGGGGGGPG 92
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 35.8 bits (81), Expect = 0.12
Identities = 55/237 (23%), Positives = 96/237 (40%), Gaps = 56/237 (23%)
Query: 434 YSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTF-DIDANGILNVT 492
Y S + Q+ E ++ DNN DL I + +++ + DI
Sbjct: 319 YQAELSQMQTQISETNVILSMDNNR--SLDLDSI------IAEVKAQYEDIAQKSKAEAE 370
Query: 493 AADKSTGKENKITITN--DKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTY 550
+ +S +E +IT D R SK +I + + +R +SE + + +++
Sbjct: 371 SLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS---------- 420
Query: 551 NIKQTVEDEKLRGKISEQD-KNKILD-----------------KCQEVINW---LDRNQM 589
N++Q++ D + RG+ + +D KNK+ D QE++N LD
Sbjct: 421 NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA 480
Query: 590 AEKDEYEHKQKELERVCNPIISKLY------------QGGPGGGSGGGGS--GASGG 632
+ E ++ + C P +S +GG GGG G GGS G+ GG
Sbjct: 481 TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGG 537
Score = 31.6 bits (70), Expect = 2.3
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 616 GGPGGGSGGGGSGASGG 632
GG GGSGGGG G+SGG
Sbjct: 585 GGYRGGSGGGGGGSSGG 601
Score = 30.0 bits (66), Expect = 6.8
Identities = 13/21 (61%), Positives = 15/21 (71%), Gaps = 2/21 (9%)
Query: 614 YQGGPGGGSGG--GGSGASGG 632
Y+GG GGG GG GG G+ GG
Sbjct: 587 YRGGSGGGGGGSSGGRGSGGG 607
Score = 29.6 bits (65), Expect = 8.9
Identities = 12/78 (15%), Positives = 35/78 (44%)
Query: 235 DFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGV 294
D + + + + E+++ K++ +I A T + + ++D+L + +
Sbjct: 253 DSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEI 312
Query: 295 DFYTSITRARFEELNADL 312
DF T++ +A ++ +
Sbjct: 313 DFLTALYQAELSQMQTQI 330
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 35.8 bits (81), Expect = 0.12
Identities = 32/126 (25%), Positives = 62/126 (49%), Gaps = 19/126 (15%)
Query: 497 STGKENKITITNDKGRLSKDDI----DRMVQEAERYKSEDEA---NRDRVAAK-NALESY 548
S+G + + G++SK+++ D + +E E+ K + +A NR + + + LE
Sbjct: 956 SSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1015
Query: 549 TYNIKQTVE-----DEKLRGKISEQDKNK------ILDKCQEVINWLDRNQMAEKDEYEH 597
N+K + E RG++ E +NK + KCQE+ +L + ++ E +H
Sbjct: 1016 LANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQH 1075
Query: 598 KQKELE 603
+K+LE
Sbjct: 1076 IRKDLE 1081
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 35.4 bits (80), Expect = 0.16
Identities = 14/22 (63%), Positives = 15/22 (68%)
Query: 616 GGPGGGSGGGGSGASGGPTIEE 637
GG GGG GGGG G GGP E+
Sbjct: 38 GGSGGGGGGGGGGGGGGPGHEQ 59
Score = 30.4 bits (67), Expect = 5.2
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 616 GGPGGGSGGGGSGASGG 632
G GGGSGGGG G GG
Sbjct: 34 GPAGGGSGGGGGGGGGG 50
>gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens]
Length = 1185
Score = 35.4 bits (80), Expect = 0.16
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 19/61 (31%)
Query: 589 MAEKDEYEHKQKELERVCNPIISKL-------------------YQGGPGGGSGGGGSGA 629
+AEK YE ++ ER+ P+ ++ Y+GGPG G+ GG +GA
Sbjct: 73 VAEKWAYERVEERFERIPEPVQRRIVYWSFPRNEREICMYSSFQYRGGPGAGAAGGAAGA 132
Query: 630 S 630
S
Sbjct: 133 S 133
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 35.0 bits (79), Expect = 0.21
Identities = 15/23 (65%), Positives = 15/23 (65%)
Query: 616 GGPGGGSGGGGSGASGGPTIEEV 638
GG GGG GGGGSG G P E V
Sbjct: 105 GGDGGGCGGGGSGGGGAPRREPV 127
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 35.0 bits (79), Expect = 0.21
Identities = 15/23 (65%), Positives = 15/23 (65%)
Query: 616 GGPGGGSGGGGSGASGGPTIEEV 638
GG GGG GGGGSG G P E V
Sbjct: 105 GGDGGGCGGGGSGGGGAPRREPV 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,810,147
Number of Sequences: 37866
Number of extensions: 1020698
Number of successful extensions: 8970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 6357
Number of HSP's gapped (non-prelim): 2016
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.