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Search of human proteins with 68509926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
(795 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 1607 0.0
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 669 0.0
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 647 0.0
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 575 e-164
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 566 e-161
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 536 e-152
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 497 e-140
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 452 e-127
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 435 e-122
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 350 2e-96
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 333 3e-91
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 315 1e-85
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 301 1e-81
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 251 2e-66
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 251 2e-66
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 251 2e-66
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 243 4e-64
gi|166851804 tudor domain containing 9 [Homo sapiens] 220 4e-57
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 192 1e-48
gi|38505213 YTH domain containing 2 [Homo sapiens] 186 1e-46
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 182 1e-45
gi|14670268 RD RNA-binding protein [Homo sapiens] 53 1e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 2e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 52 3e-06
gi|125988409 RED protein [Homo sapiens] 50 8e-06
gi|10190682 chromobox homolog 8 [Homo sapiens] 50 8e-06
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 49 2e-05
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 49 2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 48 3e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 48 3e-05
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 1607 bits (4162), Expect = 0.0
Identities = 795/795 (100%), Positives = 795/795 (100%)
Query: 1 MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE
Sbjct: 1 MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
Query: 61 LRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTN 120
LRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTN
Sbjct: 61 LRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTN 120
Query: 121 LPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRS 180
LPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRS
Sbjct: 121 LPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRS 180
Query: 181 LPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGM 240
LPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGM
Sbjct: 181 LPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGM 240
Query: 241 LLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKF 300
LLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKF
Sbjct: 241 LLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKF 300
Query: 301 QIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQE 360
QIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQE
Sbjct: 301 QIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQE 360
Query: 361 EIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVS 420
EIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVS
Sbjct: 361 EIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVS 420
Query: 421 TNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGK 480
TNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGK
Sbjct: 421 TNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGK 480
Query: 481 CFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRAL 540
CFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRAL
Sbjct: 481 CFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRAL 540
Query: 541 ELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCF 600
ELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCF
Sbjct: 541 ELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCF 600
Query: 601 VRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNV 660
VRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNV
Sbjct: 601 VRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNV 660
Query: 661 RQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQ 720
RQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQ
Sbjct: 661 RQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQ 720
Query: 721 LHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQL 780
LHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQL
Sbjct: 721 LHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQL 780
Query: 781 DRIIAKLQSKEYSQY 795
DRIIAKLQSKEYSQY
Sbjct: 781 DRIIAKLQSKEYSQY 795
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 669 bits (1726), Expect = 0.0
Identities = 343/655 (52%), Positives = 464/655 (70%), Gaps = 15/655 (2%)
Query: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
IL++R LP+++ K++ + +Q +++GETGSGKTTQI Q+ E + G +
Sbjct: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGK---IG 614
Query: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDP 249
CTQPRRVAAMSVA+RV++E LGQEVGY+IRFEDC+S +T++KYMTDGMLLRE + DP
Sbjct: 615 CTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDP 674
Query: 250 LLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPL 309
L +Y +I+LDEAHERT+ TD+L G+LK+ V++R D+K+IV SATLDA KF YF P+
Sbjct: 675 DLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPI 734
Query: 310 LTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI 369
TIPGRT+PVEI YT EPE DYL+A++ TV+QIH+ E GD+L+FLTGQEEID AC+ +
Sbjct: 735 FTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP-GDILVFLTGQEEIDTACEIL 793
Query: 370 KREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLT 429
+ LGP+V ++ I+P+YS LP + Q RIF+P PP RKVV++TNIAETSLT
Sbjct: 794 YERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGS------RKVVIATNIAETSLT 847
Query: 430 IDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKA 489
IDG+ +V+DPGF KQKVYN + ++ L+VT IS+A A+QRAGRAGRT PGKC+RLYTE+A
Sbjct: 848 IDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERA 907
Query: 490 YKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 549
Y+ EM PEI R+NL S VL LK +GI+DL+ FDFMD P ETL+ A+E L L AL
Sbjct: 908 YRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
Query: 550 NDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKA 609
+D+G LT LG MAEFPL+P L KM+I S CS E+L+I +MLSV F RP + +
Sbjct: 968 DDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQAL 1027
Query: 610 ADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMD 669
AD+ K +F +GDHLTLL VY+++K N S WCY+NFI RSL A ++R+Q+ IMD
Sbjct: 1028 ADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMD 1087
Query: 670 RFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-D 728
R L S ++ + ++KA+ +G+F A + Y T+ D QVV +HPS+ L +
Sbjct: 1088 RHKLDVVSCGKST----VRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFN 1143
Query: 729 HKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRI 783
+PEWV+Y+E VLTTK Y+R T I P WLV+ AP ++ +S+ + +++ R+
Sbjct: 1144 RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRL 1198
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query: 12 DYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
D KKR+ + ++RDRDRDRE R++DRD +R R R R + +E+
Sbjct: 169 DRTKKKKRSRSRDRNRDRDRDRE-RNRDRDHKRRHRSRSRSRSRTRER 215
Score = 37.7 bits (86), Expect = 0.042
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 11 EDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKELRASTN 66
E + R T K R R RDR DR +DR+R RDR + R R + + + N
Sbjct: 160 EKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERN 216
Score = 36.2 bits (82), Expect = 0.12
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 7/45 (15%)
Query: 24 GKDRDRDRDRED------RSKDRDRERDRGDREREREKEKEKELR 62
G+++ RD + D RS+ RDR RDR DR+RER ++++ + R
Sbjct: 158 GQEKQRDAEHRDRTKKKKRSRSRDRNRDR-DRDRERNRDRDHKRR 201
Score = 32.7 bits (73), Expect = 1.4
Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
+DRDR+R+R+ K R R R R R R RE+ K K
Sbjct: 186 RDRDRERNRDRDHKRRHRSRSR-SRSRTRERNKVK 219
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 647 bits (1668), Expect = 0.0
Identities = 338/652 (51%), Positives = 451/652 (69%), Gaps = 16/652 (2%)
Query: 134 RLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQP 193
R LPV+ +++ + HQ ++ GETGSGKTTQIPQ+ E + G K +ACTQP
Sbjct: 396 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMK--IACTQP 453
Query: 194 RRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLER 253
RRVAAMSVA RVA EM V LG EVGYSIRFEDC+S +T+L+YMTDGMLLRE +++P L
Sbjct: 454 RRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLAS 513
Query: 254 YGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIP 313
Y V+++DEAHERTL TDIL G++K+V R R +LKV+V SAT+D +F +FD+ P+ IP
Sbjct: 514 YSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIP 573
Query: 314 GRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREV 373
GR PV+IFYT PE DYLEA + +V+QIH+ + GD+L+FLTGQEEI+ AC+ ++
Sbjct: 574 GRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP-GDILVFLTGQEEIEAACEMLQDPC 632
Query: 374 DDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGV 433
LG ++ ++ ++P+Y+ LP Q RIF+P PP GA RKVVV+TNIAETS TI+G+
Sbjct: 633 RRLGSKIRELLVLPIYANLPSDMQARIFQPTPP----GA--RKVVVATNIAETSPTIEGI 686
Query: 434 VFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTE 493
++V+DPGF KQK YNPR +ESL VT SKASA QRAGRAGR GKCFRLYT AY+ E
Sbjct: 687 IYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHE 746
Query: 494 MQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDG 553
+++ T PEI R++LG+VVL LK LGI DL+HFDF+DPP ETL+ LE L L ALN G
Sbjct: 747 LEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNHLG 806
Query: 554 DLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSV-PQCFVRPTEAKKAADE 612
+LT G MAE P+DP L+KM++AS Y+CS E+L++ AMLSV F RP + AD
Sbjct: 807 ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADN 866
Query: 613 AKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFN 672
A++ F GDHL LLNVY + ++ S QWC +NF+ +RS+ A +VR+QL +++R
Sbjct: 867 ARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVREQLEGLLERVE 926
Query: 673 LPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHP-STVLDHKP 731
+ S + YI +RKA+ GYF A L R+G Y TVK Q V +HP S++ + +P
Sbjct: 927 VGLSS----CQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTVFIHPNSSLFEQQP 981
Query: 732 EWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRI 783
W+LY+E VLTTK ++R +I+ WL+++AP YY AK+ +I
Sbjct: 982 RWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKI 1033
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 575 bits (1482), Expect = e-164
Identities = 303/662 (45%), Positives = 438/662 (66%), Gaps = 25/662 (3%)
Query: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
IL++R LP++ + I+ + ++VGETGSGKTTQ+ Q+ E + G +
Sbjct: 525 ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM---IG 581
Query: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDP 249
CTQPRRVAAMSVA+RV++EM LG+EVGY+IRFEDC+S T++KYMTDG+LLRE++ +
Sbjct: 582 CTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREA 641
Query: 250 LLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPL 309
L+ Y II+DEAHER+L TD+L G+L+EVV +RSDLK+IV SAT+DA KF +F N P+
Sbjct: 642 DLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPI 701
Query: 310 LTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI 369
IPGRT PV+I ++ P+ DY+EAA++ +Q+H+ GD+L+F+ GQE+I+ +I
Sbjct: 702 FHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHL-SGAPGDILIFMPGQEDIEVTSDQI 760
Query: 370 KREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLT 429
+++L + ++P+YS LP Q +IF+ P +G RK +V+TNIAETSLT
Sbjct: 761 VEHLEEL-ENAPALAVLPIYSQLPSDLQAKIFQKAP----DGV--RKCIVATNIAETSLT 813
Query: 430 IDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKA 489
+DG++FVID G+ K KV+NPRI +++L + IS+A+A QR+GRAGRT PG+CFRLYT+ A
Sbjct: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873
Query: 490 YKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 549
YK E+ T PEI R+NL +VVL LK LG+ DL+ F FMDPP + ++ ++ L L AL
Sbjct: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL 933
Query: 550 NDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKA 609
++ G LT G +M EFPLDP L+KM+I SCD CS+E+L I +MLSVP F RP ++
Sbjct: 934 DNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEE 993
Query: 610 ADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIM- 668
+D+ + +FA + DHLT LNVY +K N+ S WC D+FI+ +++ VR QL IM
Sbjct: 994 SDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMV 1053
Query: 669 -DRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL 727
R +L TD+ +RK + YF Q A L+ G Y+ ++ LHP++ L
Sbjct: 1054 QQRMSLASCGTDWDI------VRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSL 1107
Query: 728 ---DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRII 784
+ P++++Y+E V+TTK Y++ T + EWL ++ P +Y + Q RQ +R
Sbjct: 1108 FGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVK---QAGKSRQENRRR 1164
Query: 785 AK 786
AK
Sbjct: 1165 AK 1166
Score = 33.1 bits (74), Expect = 1.0
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDR-ERDRGDREREREKEKE 58
K+++ DR RDRD DRS+ R ERD G R E E
Sbjct: 156 KEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPE 198
Score = 30.8 bits (68), Expect = 5.2
Identities = 18/55 (32%), Positives = 27/55 (49%)
Query: 3 KRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEK 57
+R R + G S +++ K RDRD DR+ +RDR R ER+ E+
Sbjct: 136 ERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSER 190
Score = 30.0 bits (66), Expect = 8.8
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 25 KDRDRDRDREDRSKDRD-RERDRGDREREREKEKEKELR 62
K++ RDRD DR +DRD R+R R ER+ E+ R
Sbjct: 156 KEKSRDRD-YDRKRDRDERDRSRHSSRSERDGGSERSSR 193
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 566 bits (1459), Expect = e-161
Identities = 297/665 (44%), Positives = 443/665 (66%), Gaps = 30/665 (4%)
Query: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
I ++R +LPV++ ++ ++ +Q+ V+VGETG GK+TQIPQ+ E + G R V
Sbjct: 47 IEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEG--RVVG 104
Query: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSA-KTILKYMTDGMLLREAMND 248
TQPRRVAA++VA RVA+E +LG EVGY IRF+DC+ T +K++TDGML+RE M D
Sbjct: 105 VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVD 164
Query: 249 PLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYF---- 304
PLL +Y VI+LDEAHERTL TDI +G+LK++ ++R DL++IV SATLDA KF+ +F
Sbjct: 165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNE 224
Query: 305 ------DNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTG 358
D C +LT+ GRT PV+IFY P DY+++ + TV++IH E + GD+L FLTG
Sbjct: 225 TSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGD-GDVLAFLTG 283
Query: 359 QEEIDEACKRIKREVDDLGPE--VGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRK 416
QEE++ + + L ++++P+Y+ LP +Q ++FE + RK
Sbjct: 284 QEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFE------RVSRSVRK 337
Query: 417 VVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRT 476
V+V+TN+AETS+TI G+V+VID GF K + YNPR +E L+V +S+ASA QRAGR GR+
Sbjct: 338 VIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRS 397
Query: 477 RPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETL 536
R GKC+RLYTE+A+ ++ +T PE+ RSNL V+LQLK LGID+++ F FM PP +++
Sbjct: 398 RSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSM 456
Query: 537 MRALELLNYLAALNDDGDLTE-LGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLS 595
++ALELL L L+ D LTE LG +AEFPL+P AKM++ S ++ CS E+LSI AM+
Sbjct: 457 VQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQ 516
Query: 596 VPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLM 655
+ FV P K A +FA +GDHLT+LN+Y AF ++++ +WC ++F+NY+ L+
Sbjct: 517 IQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLV 576
Query: 656 SADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKD 715
A VR+QL +++ +F +PR+S++ + + +V+G+F A TG Y T++D
Sbjct: 577 RAATVREQLKKLLVKFQVPRKSSEGDPD----LVLRCIVSGFFANAARFHSTGAYRTIRD 632
Query: 716 NQVVQLHPSTVL--DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQ 773
+ + +HP++VL + P WV+YNE + T+K Y+R T I+ WL+++AP +Y
Sbjct: 633 DHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLS 692
Query: 774 CEAKR 778
+AKR
Sbjct: 693 LKAKR 697
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 536 bits (1382), Expect = e-152
Identities = 285/686 (41%), Positives = 446/686 (65%), Gaps = 21/686 (3%)
Query: 115 INPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWC 174
+NPF LP++ RYY +LK+R LP+W+ K F + L+++Q ++ G+ GK+ Q+PQWC
Sbjct: 40 LNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWC 99
Query: 175 VEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILK 234
EY S+ GV CTQ + + +A RVADEMDV +G EVGY I FE+C + +TIL+
Sbjct: 100 AEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILR 159
Query: 235 YMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSAT 294
Y TD ML RE M++P L YGVIILD+ HER++ATD+L+G+LK+V+ R +LK+I+ S+
Sbjct: 160 YCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSP 219
Query: 295 LDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLL 354
K Y+ N P++ + + HPVE+ Y E ++D E+ +R + +IH E+GD+++
Sbjct: 220 HLISKLNSYYGNVPVIEVKNK-HPVEVVYLSEAQKDSFESILRLIFEIHH-SGEKGDIVV 277
Query: 355 FLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEP-PPPKKQNGAI 413
FL +++I++ C+ + + +L P++G++ ++PLY P+++ +F+P +K+
Sbjct: 278 FLACEQDIEKVCETV-YQGSNLNPDLGELVVVPLY----PKEKCSLFKPLDETEKRCQVY 332
Query: 414 GRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRA 473
R+VV++T+ E + + V FVID G ++KVYNPRIR SL++ IS++ A+ R
Sbjct: 333 QRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQIL 392
Query: 474 GRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAP 533
G + GK F LYTE+ +M E+ +NL S+VL +K++ I L H DFM+ PAP
Sbjct: 393 GSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAP 452
Query: 534 ETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAM 593
E+LM+ALE L+YLAAL++DG+L+E G +M+EFPLDPQL+K ++ASC+++C +EVL+I AM
Sbjct: 453 ESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAM 512
Query: 594 LSVPQCFVR-PTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQ---NHES----VQWCY 645
++ P CF P A++AA F H +GDH TL+++Y A++ N S +WC
Sbjct: 513 VTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCR 572
Query: 646 DNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAH-L 704
D F+N +L AD +R +L I+ R LP F S++ +NI+KAL++GYFMQ+A +
Sbjct: 573 DYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDV 632
Query: 705 ERTGHYLTVKDNQVVQLHP---STVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKI 761
+ +G+YL + QV QLHP ++ PEWVL+++F ++ NYIR ++I PE +++
Sbjct: 633 DGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQL 692
Query: 762 APQYYDMSNFPQCEAKRQLDRIIAKL 787
PQYY SN P E+K L +++ L
Sbjct: 693 VPQYY-FSNLPPSESKDILQQVVDHL 717
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
sapiens]
Length = 707
Score = 497 bits (1279), Expect = e-140
Identities = 276/646 (42%), Positives = 397/646 (61%), Gaps = 29/646 (4%)
Query: 133 KRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQ 192
+R LP+++ + + L + VL+GETGSGKTTQIPQ+ E S G +A TQ
Sbjct: 70 QRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGI---IAVTQ 126
Query: 193 PRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLE 252
PRRVAA+S+A RV+DE LG+ VGY++RF+D +S T +K++TDGMLLREA++D LL
Sbjct: 127 PRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLR 186
Query: 253 RYGVIILDEAHERTLATDILMGVLKEVVRQRSD-----LKVIVMSATLDAGKFQIYFDNC 307
+Y +ILDEAHERT+ TD+L GV+K ++R + LKVIVMSAT+D F YF+
Sbjct: 187 KYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGA 246
Query: 308 PLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEID---E 364
P+L + GR HP+++FYT +P+ DYL AA+ +V QIH D+L+FLTGQEEI+ +
Sbjct: 247 PVLYLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSK 306
Query: 365 ACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIA 424
C+ I + + D P + ++PLY++LP QQ R+F+ P RKV++STNIA
Sbjct: 307 TCRDIAKHLPDGCPA---MLVLPLYASLPYAQQLRVFQGAPKGY------RKVIISTNIA 357
Query: 425 ETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRL 484
ETS+TI G+ +V+D G K K YNP +E L V +SK A QR GRAGR G C+RL
Sbjct: 358 ETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRL 417
Query: 485 YTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLN 544
YTE ++ + T PEI R NL SV+LQL + + +++ FDFM P+P+ + A+ L+
Sbjct: 418 YTEDEFE-KFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLD 476
Query: 545 YLAALNDDGD---LTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFV 601
L AL D LT +G MA FPL+P+ AK ++ S ++C+ E+L+I ++LSV
Sbjct: 477 LLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLH 536
Query: 602 RPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVR 661
P ++ + +F +GDH+TLLN+Y FK + WC +NF+N +++ VR
Sbjct: 537 NPPSRREEVQGVRKKFISSEGDHMTLLNIYRTFKNLGGNKDWCKENFVNSKNMTLVAEVR 596
Query: 662 QQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQL 721
QL I + ++P S SR ++R+ L FM A L+ G Y T +Q V +
Sbjct: 597 AQLRDICLKMSMPIAS----SRGDVESVRRCLAHSLFMSTAELQPDGTYATTDTHQPVAI 652
Query: 722 HPSTVLDH-KPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYY 766
HPS+VL H KP V+Y E + T K Y+R I +WL + AP+Y+
Sbjct: 653 HPSSVLFHCKPACVVYTELLYTNKCYMRDLCVIDAQWLYEAAPEYF 698
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
sapiens]
Length = 779
Score = 452 bits (1164), Expect = e-127
Identities = 270/651 (41%), Positives = 390/651 (59%), Gaps = 45/651 (6%)
Query: 151 VRHQSFVLV-GETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEM 209
VR SF++V G TGSGKTTQ+P++ E S G + TQPR+VAA+SVAQRVA+EM
Sbjct: 66 VRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRKVAAISVAQRVAEEM 122
Query: 210 DVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLAT 269
LG +VGY +RF+DCSS +T +KYMTDG LL+ + DP L ++ VIILDEAHERTL T
Sbjct: 123 KCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTT 182
Query: 270 DILMGVLKEVVRQRSD-----LKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV-EIFY 323
DIL G+LK++ +++S LKV+VMSAT++ K +F NCP+ IPGR +PV E F
Sbjct: 183 DILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFC 242
Query: 324 TPEPERD-----YLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVD--DL 376
RD Y++A + + IH+ E GD+L+FLTGQ EI+++C+ + + + D
Sbjct: 243 NLIGPRDRENTAYIQAIVEVTMDIHL-NEMAGDILVFLTGQFEIEKSCELLFQMAESVDY 301
Query: 377 GPEVGD-----IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTID 431
+V D + I+P Y ++ QQ+RIF PPPP RK V+STNI+ TSLTID
Sbjct: 302 DYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGI------RKCVISTNISATSLTID 355
Query: 432 GVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYK 491
G+ +V+D GF KQ +NPR+ ++ L V ISK+ A QR+GRAGRT GKCFR+Y++ +
Sbjct: 356 GIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWN 415
Query: 492 TEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALND 551
M D+ PEI R++L SVVL LK L I D++ F ++DPP ++ AL+ L A++
Sbjct: 416 QCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDR 475
Query: 552 DGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPT--EAKKA 609
G +T LG M EFPL P L VI + +C + +L I AMLSV F+RP E +K
Sbjct: 476 SGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKE 535
Query: 610 ADEAKMRFAHIDG---DHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSR 666
A++ A G D TL ++ K + WC ++I++R L SA V QL
Sbjct: 536 AEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRE 595
Query: 667 IMDRFNLPRRSTDFTSRDY----YINIRKALVTGYFMQVAHLERTGHYLTVKD-NQVVQL 721
++ + ++ +DF + + +R+ L GYF VA + TV V +
Sbjct: 596 LIRKL---KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHI 652
Query: 722 HPSTVL---DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMS 769
HPS+ L + K EW++++E ++TTK Y R I+ EW+ + P+ ++ +
Sbjct: 653 HPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFN 703
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 435 bits (1118), Expect = e-122
Identities = 262/685 (38%), Positives = 404/685 (58%), Gaps = 32/685 (4%)
Query: 115 INPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLV--GETGSGKTTQIPQ 172
+NPF LP + RYY++LK+R LP+W + F + L + + V++ GE GSGK+TQIPQ
Sbjct: 23 VNPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQ 82
Query: 173 WCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTI 232
WC E+ + K V TQP +AA S+A RVADEMD+ LG EVGYSI EDC+ T+
Sbjct: 83 WCAEFALARGFQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTL 142
Query: 233 LKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQR--SDLKVIV 290
L++ D +LL+E + +GV++LDEA ER++A+D L G+L++ ++ DL+V+V
Sbjct: 143 LRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVV 202
Query: 291 MSATLDAGKFQIYFDNCPLLTIPGRT--HPVEIFYTPEPERDYLEAAIRTVIQIHMCEEE 348
++ K + ++ N P++ IP P I++ P D +EAA + V+++ C +E
Sbjct: 203 VTDPALEPKLRAFWGNPPIVHIPREPGERPSPIYWDTIPP-DRVEAACQAVLEL--CRKE 259
Query: 349 -EGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPK 407
GD+L+FL +EEI C+ + REV+ L + +++PL+ + Q ++E
Sbjct: 260 LPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCG-RAVQAVYEDMD-- 316
Query: 408 KQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQ 467
RKVVV+ +A+ S ++ + VID G + VYNPRIR E ++ ISK A+
Sbjct: 317 ------ARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAE 370
Query: 468 QRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDF 527
R RA PG C LY + + E P + NL S+VL LK+ I + F
Sbjct: 371 ARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHF 430
Query: 528 MDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEV 587
+D PAPE LM+ALE L+YLAAL+DDGDL++LG +++EFPL P+LAK ++ASC+++C +E+
Sbjct: 431 LDQPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEM 490
Query: 588 LSITAMLSVPQCFVRPTEAKKAADEAKMRFA--HIDGDHLTLLNVYHAFKQNHESVQWCY 645
L++ AML+ F RP +A+EA +R A H DGDH +L+ VY AF Q+ WC
Sbjct: 491 LTLAAMLTAAPGFTRP---PLSAEEAALRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQ 547
Query: 646 DNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAH-L 704
+N+ +L A +R +L +M R LP F S +++KALV+GYF++VA
Sbjct: 548 ARGLNWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDT 607
Query: 705 ERTGHYLTVKDNQVVQLHPSTVLDHK------PEWVLYNEFVLTTKNYIRTCTDIKPEWL 758
+ TG+YL + V QL + P WVLY+ F ++ N + ++I+P+ L
Sbjct: 608 DGTGNYLLLTHKHVAQLSSYCCYRSRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQML 667
Query: 759 VKIAPQYYDMSNFPQCEAKRQLDRI 783
V++AP Y+ +SN P E++ L+++
Sbjct: 668 VELAPPYF-LSNLPPSESRDLLNQL 691
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 350 bits (899), Expect = 2e-96
Identities = 213/563 (37%), Positives = 306/563 (54%), Gaps = 32/563 (5%)
Query: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPK 185
R + ++R LP+ +Y +R L HQ V+ G+TG GK+TQ+PQ+ L
Sbjct: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYL------LAAGF 204
Query: 186 RGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREA 245
VACTQPRR+A +S+A+RV E G +VGY IRFE SA T + ++T G+LLR+
Sbjct: 205 SHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQI 264
Query: 246 MNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFD 305
+P L +Y V+I+DE HER L D L+GVL+ ++ R DLKVI+MSAT++ F YF
Sbjct: 265 QREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFS 324
Query: 306 NCPLLTIPGRTHPVEIFYTP---EPERDYLE-------AAIRTVIQIHMCEEEEGDLLLF 355
N P++ +PGR P+ + Y P EP E + I EE GDLL+F
Sbjct: 325 NAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVF 384
Query: 356 LTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGR 415
L+G EI + + V ++PL+S L Q ++F+ PP R
Sbjct: 385 LSGMAEISAVLEAAQTYASHTQRWV----VLPLHSALSVADQDKVFDVAPPGV------R 434
Query: 416 KVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 475
K ++STNIAETS+TIDG+ FV+D G K+ Y+P+ +++ L IS+ASA+QR GRAGR
Sbjct: 435 KCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGR 494
Query: 476 TRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPET 535
T PG CFRLY E Y PEI R L S+VLQ+K + + D F F++PP P +
Sbjct: 495 TGPGVCFRLYAESDYDA-FAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPAS 553
Query: 536 LMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLS 595
L A+ L AL+ LT +GS++A+ P+D + KM+I ++ VL+I A LS
Sbjct: 554 LETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALS 613
Query: 596 VPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQ-----NHESVQWCYDNFIN 650
V F R ++ A+ GD TL NV++A+ Q + S +WC I
Sbjct: 614 VQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIE 673
Query: 651 YRSLMSADNVRQQLSRIMDRFNL 673
L N+R+Q +++ L
Sbjct: 674 EHRLYEMANLRRQFKELLEDHGL 696
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 333 bits (855), Expect = 3e-91
Identities = 191/394 (48%), Positives = 261/394 (66%), Gaps = 29/394 (7%)
Query: 151 VRHQSFVLV-GETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEM 209
VR SF++V G TGSGKTTQ+P++ E S G + TQPR+VAA+SVAQRVA+EM
Sbjct: 66 VRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRKVAAISVAQRVAEEM 122
Query: 210 DVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLAT 269
LG +VGY +RF+DCSS +T +KYMTDG LL+ + DP L ++ VIILDEAHERTL T
Sbjct: 123 KCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTT 182
Query: 270 DILMGVLKEVVRQRS-----DLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV-EIFY 323
DIL G+LK++ +++S LKV+VMSAT++ K +F NCP+ IPGR +PV E F
Sbjct: 183 DILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFC 242
Query: 324 TPEPERD-----YLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI--KREVDDL 376
RD Y++A ++ + IH+ E GD+L+FLTGQ EI+++C+ + E D
Sbjct: 243 NLIGPRDRENTAYIQAIVKVTMDIHL-NEMAGDILVFLTGQFEIEKSCELLFQMAESVDY 301
Query: 377 GPEVGD-----IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTID 431
+V D + I+P Y ++ QQ+RIF PPPP RK V+STNI+ TSLTID
Sbjct: 302 DYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGI------RKCVISTNISATSLTID 355
Query: 432 GVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYK 491
G+ +V+D GF KQ +NPR+ ++ L V ISK+ A QR+GRAGRT GKCFR+Y++ +
Sbjct: 356 GIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWN 415
Query: 492 TEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF 525
M D+ PEI R++L SVVL LK L I D++ +
Sbjct: 416 QCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 315 bits (807), Expect = 1e-85
Identities = 225/726 (30%), Positives = 360/726 (49%), Gaps = 102/726 (14%)
Query: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGP 184
RY ++ R +LP + + +++ HQ V+ GETG GKTTQ+ Q+ ++ Y+ G
Sbjct: 196 RYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGS 255
Query: 185 KRGVACTQPRRVAAMSVAQRVADEMDVMLGQ--EVGYSIRFEDCSSAKT-ILKYMTDGML 241
+ CTQPRR++A+SVA+RVA E G GY IR + K + Y T G++
Sbjct: 256 ACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGII 315
Query: 242 LREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQ 301
L+ +DP L I+LDE HER L +D+LM V+K+++ RSDLKVI+MSATL+A KF
Sbjct: 316 LQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375
Query: 302 IYFDNCPLLTIPGRTHPV----------EIFYTPEPER---------------------- 329
YF NCP++ IPG T PV +I Y PE +
Sbjct: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEK 435
Query: 330 ---------DYLEAAIR------------------------TVIQIHMCEEEEGDLLLFL 356
DY+ R +I+ + EEE+G +L+FL
Sbjct: 436 EAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFL 495
Query: 357 TGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRK 416
G + I + +V + IIPL+S +P Q ++F+ PP RK
Sbjct: 496 PGWDNISTLHDLLMSQVMFKSDK---FLIIPLHSLMPTVNQTQVFKRTPPGV------RK 546
Query: 417 VVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRT 476
+V++TNIAETS+TID VV+VID G K+ ++ + + ++ +SKA+A+QR GRAGR
Sbjct: 547 IVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 606
Query: 477 RPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPE 534
+PG C+ LY + + D PEILR+ L + LQ+K L + + +F MDPP+ E
Sbjct: 607 QPGHCYHLY-NGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNE 665
Query: 535 TLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAML 594
++ ++ L L AL+ +LT LG +A P++P + KM++ + C + VL+I A L
Sbjct: 666 AVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASL 725
Query: 595 SVPQCFVRPTEAKKAADEAKMRFA-HIDGDHLTLLNVYHAFKQNHE-----SVQWCYDNF 648
S FV P +K AD + A DHLT++N + +++ +C++ F
Sbjct: 726 SFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYF 785
Query: 649 INYRSLMSADNVRQQLSRIMDRFNL-----PRRSTDFTSRDYYINIRKALVTGYFMQVAH 703
++ +L N++ Q + + P+ + D I+ + G + +VA
Sbjct: 786 LSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAK 845
Query: 704 L------ERTGHYLTVKDNQVVQLHPSTV----LDHKPEWVLYNEFVLTTKNYIRTCTDI 753
+ +R + K + +V +HP +V D W++Y+ + T+ Y+ CT++
Sbjct: 846 IRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEV 905
Query: 754 KPEWLV 759
P L+
Sbjct: 906 SPYCLL 911
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 301 bits (772), Expect = 1e-81
Identities = 220/710 (30%), Positives = 358/710 (50%), Gaps = 84/710 (11%)
Query: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGP 184
RY ++ R +LP + + +++ HQ V+ GETG GKTTQ+ Q+ ++ Y+ G
Sbjct: 196 RYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGS 255
Query: 185 KRGVACTQPRRVAAMSVAQRVADEMDVMLGQ--EVGYSIRFEDCSSAKT-ILKYMTDGML 241
+ CTQPRR++A+SVA+RVA E G GY IR + K + Y T G++
Sbjct: 256 ACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGII 315
Query: 242 LREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQ 301
L+ +DP L I+LDE HER L +D+LM V+K+++ RSDLKVI+MSATL+A KF
Sbjct: 316 LQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFS 375
Query: 302 IYFDNCPLLTIPGRTHPV----------EIFYTPEPERDYLEAAIRTVIQIHMC--EEEE 349
YF NCP++ IPG T PV +I Y PE ++++ R +Q H+ E+EE
Sbjct: 376 EYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPE-QKEHRSQFKRGFMQGHVNRQEKEE 434
Query: 350 GDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKI------------------------ 385
+ + + + E +R D+ + D K+
Sbjct: 435 KEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVF 494
Query: 386 IP-------LYSTLPPQ------QQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDG 432
+P L+ L Q Q ++F+ PP RK+V++TNIAETS+TID
Sbjct: 495 LPGWDNISTLHDLLMSQVMFKSVNQTQVFKRTPPGV------RKIVIATNIAETSITIDD 548
Query: 433 VVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKT 492
VV+VID G K+ ++ + + ++ +SKA+A+QR GRAGR +PG C+ LY +
Sbjct: 549 VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLY-NGLRAS 607
Query: 493 EMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALN 550
+ D PEILR+ L + LQ+K L + + +F MDPP+ E ++ ++ L L AL+
Sbjct: 608 LLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALD 667
Query: 551 DDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAA 610
+LT LG +A P++P + KM++ + C + VL+I A LS FV P +K A
Sbjct: 668 KQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIA 727
Query: 611 DEAKMRFA-HIDGDHLTLLNVYHAFKQNHE-----SVQWCYDNFINYRSLMSADNVRQQL 664
D + A DHLT++N + +++ +C++ F++ +L N++ Q
Sbjct: 728 DARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQF 787
Query: 665 SRIMDRFNL-----PRRSTDFTSRDYYINIRKALVTGYFMQVAHL------ERTGHYLTV 713
+ + P+ + D I+ + G + +VA + +R +
Sbjct: 788 AEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYT 847
Query: 714 KDNQVVQLHPSTV----LDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLV 759
K + +V +HP +V D W++Y+ + T+ Y+ CT++ P L+
Sbjct: 848 KTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLL 897
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
Length = 1155
Score = 251 bits (641), Expect = 2e-66
Identities = 170/529 (32%), Positives = 284/529 (53%), Gaps = 41/529 (7%)
Query: 136 QLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGPKRGVACTQPR 194
QLPV ++D + + +H V+ G+TG GKTT+IPQ +E Y+ G + V TQPR
Sbjct: 394 QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 453
Query: 195 RVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKT-ILKYMTDGMLLREAMNDPLLER 253
R++A+SVAQRV+ E+ L + VG+ +R E ++ L + T G+LLR+ ++P LE
Sbjct: 454 RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 513
Query: 254 YGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIP 313
+I+DE HER + TD L+ +LK + R L++++MSAT D +F YF CP++ +P
Sbjct: 514 VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 573
Query: 314 GRTHPVEIFYTPE-------------------PERDYLEAAIRTVIQIHM-CEEEEGDLL 353
G +PV+ Y + + L+ + T + +H+ E G +L
Sbjct: 574 GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 633
Query: 354 LFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAI 413
FL G +EI +R++ + LG I+P++S +P Q+ IF+ PP +
Sbjct: 634 CFLPGWQEIKGVQQRLQ---EALGMHESKYLILPVHSNIPMMDQKAIFQQPP-------V 683
Query: 414 G-RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGR 472
G RK+V++TNIAETS+TI+ +V V+D G K++ Y+ + +V L +S+A+ QR GR
Sbjct: 684 GVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGR 743
Query: 473 AGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFM---- 528
AGR + G + L+ + +M PEILR+ L ++VLQ K+ + + +F+
Sbjct: 744 AGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLSKAV 801
Query: 529 DPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 588
D P + + A+ LL + L+ LT LG +A DP+LAK ++ + + C + +L
Sbjct: 802 DSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLL 861
Query: 589 SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDG-DHLTLLNVYHAFKQ 636
+ + L+ F + + D+ K +H G DHL + +++
Sbjct: 862 VVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEE 909
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
[Homo sapiens]
Length = 1194
Score = 251 bits (641), Expect = 2e-66
Identities = 170/529 (32%), Positives = 284/529 (53%), Gaps = 41/529 (7%)
Query: 136 QLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGPKRGVACTQPR 194
QLPV ++D + + +H V+ G+TG GKTT+IPQ +E Y+ G + V TQPR
Sbjct: 433 QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 492
Query: 195 RVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKT-ILKYMTDGMLLREAMNDPLLER 253
R++A+SVAQRV+ E+ L + VG+ +R E ++ L + T G+LLR+ ++P LE
Sbjct: 493 RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 552
Query: 254 YGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIP 313
+I+DE HER + TD L+ +LK + R L++++MSAT D +F YF CP++ +P
Sbjct: 553 VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 612
Query: 314 GRTHPVEIFYTPE-------------------PERDYLEAAIRTVIQIHM-CEEEEGDLL 353
G +PV+ Y + + L+ + T + +H+ E G +L
Sbjct: 613 GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 672
Query: 354 LFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAI 413
FL G +EI +R++ + LG I+P++S +P Q+ IF+ PP +
Sbjct: 673 CFLPGWQEIKGVQQRLQ---EALGMHESKYLILPVHSNIPMMDQKAIFQQPP-------V 722
Query: 414 G-RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGR 472
G RK+V++TNIAETS+TI+ +V V+D G K++ Y+ + +V L +S+A+ QR GR
Sbjct: 723 GVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGR 782
Query: 473 AGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFM---- 528
AGR + G + L+ + +M PEILR+ L ++VLQ K+ + + +F+
Sbjct: 783 AGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLSKAV 840
Query: 529 DPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 588
D P + + A+ LL + L+ LT LG +A DP+LAK ++ + + C + +L
Sbjct: 841 DSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLL 900
Query: 589 SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDG-DHLTLLNVYHAFKQ 636
+ + L+ F + + D+ K +H G DHL + +++
Sbjct: 901 VVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEE 948
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
sapiens]
Length = 1270
Score = 251 bits (640), Expect = 2e-66
Identities = 174/607 (28%), Positives = 307/607 (50%), Gaps = 79/607 (13%)
Query: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGPKRGV 188
IL++R LPV +++ + + ++ ++ G TG GKTTQ+PQ+ ++ ++++ + +
Sbjct: 381 ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440
Query: 189 ACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDC-SSAKTILKYMTDGMLLREAMN 247
TQPRR++A+SVA+RVA E G+ GYS+RFE + + T G+LLR+
Sbjct: 441 VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL-- 498
Query: 248 DPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNC 307
+ + +I+DE HER + TD L+ VL++VV+ ++++++MSAT+D F YF NC
Sbjct: 499 EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558
Query: 308 PLLTIPGRTHPVEIFYTPE---------PERDYL----------------------EAAI 336
P++ + GRT+PV+ ++ + P +D E
Sbjct: 559 PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618
Query: 337 RTVIQIHMCEEEE-------------------GDLLLFLTGQEEIDEACKRIKREVDDLG 377
T + + E+E G +L+FL G I K + ++
Sbjct: 619 ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHL-----EMN 673
Query: 378 PEVGD--IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIG-RKVVVSTNIAETSLTIDGVV 434
P G +I+PL+S +P ++Q+++F+P P +G KV++STNIAETS+TI+ VV
Sbjct: 674 PHFGSHRYQILPLHSQIPREEQRKVFDPVP-------VGVTKVILSTNIAETSITINDVV 726
Query: 435 FVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEM 494
+VID K K++ + + SK + +QR GRAGR RPG CF L + ++ +
Sbjct: 727 YVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE-RL 785
Query: 495 QDNTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALNDD 552
+ + PE+ R+ L + L +K L + + F ++PP + ++ A L L AL+ +
Sbjct: 786 ETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDAN 845
Query: 553 GDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADE 612
+LT LG ++A+ P++P+ KM+I C + + + +I A P+ F+ E K+
Sbjct: 846 DELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFI--NEGKRLGYI 903
Query: 613 AKMRFAHIDGDHLTLLNVYHAFKQ-----NHESVQWCYDNFINYRSLMSADNVRQQLSRI 667
+ + DH+ LL+V+ A+ +++C +N +L + QL I
Sbjct: 904 HRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEI 963
Query: 668 MDRFNLP 674
+ P
Sbjct: 964 LINSGFP 970
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 243 bits (621), Expect = 4e-64
Identities = 225/845 (26%), Positives = 361/845 (42%), Gaps = 144/845 (17%)
Query: 40 RDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAH 99
RD + D E++RE+ + E + + I+ L LK HS + ++
Sbjct: 463 RDVWLEWSDAEKKREELNKMETNKPRD-LFIAKLLNKLKQQQQQQQQHSENKRENSEDPE 521
Query: 100 STHAG-------------HAGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRF 146
+ A L N F L TP+Y +LK+R QLPV++++D
Sbjct: 522 ESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSI 581
Query: 147 TDILVRHQSFVLVGETGSGKTTQIPQWCVE--YMRSLPGPKRGVACTQPRRVAAMSVAQR 204
+ L RH+ V+ GETGSGK+TQ+P + +E + K + CTQPRR++A+S+A R
Sbjct: 582 VETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANR 641
Query: 205 VADEMDVMLGQE-----VGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIIL 259
V DE+ G GY IR E + T L Y T G+LLR+ D LL +I+
Sbjct: 642 VCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIV 701
Query: 260 DEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV 319
DE HER++ +D L+ +LKE++++RSDL +I+MSAT+D+ KF YF +CP+L I GR++PV
Sbjct: 702 DEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPV 761
Query: 320 EIFYTPE--PERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLG 377
E+F+ + E ++ Q + EEEE + + IK+ + +
Sbjct: 762 EVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTI--------NVTSKAGGIKKYQEYIP 813
Query: 378 PEVG-DIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFV 436
+ G + P Y + Q I P K N + +++ + + I+G V +
Sbjct: 814 VQTGAHADLNPFYQKYSSRTQHAILY-MNPHKINLDLILELLAYLDKSPQFRNIEGAVLI 872
Query: 437 IDPGFA-----------KQKVYNPRIRV---ESLLVT------------AISKASAQQRA 470
PG A ++ Y+ R +V S+L T + K
Sbjct: 873 FLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNI 932
Query: 471 GRAGRTRPGKCFRLYT----EKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF- 525
G T P F + T E Y Q ++ E S ++ Q + + D F
Sbjct: 933 AETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFR 992
Query: 526 --------DFMDPPAPETL-----------------------------------MRALEL 542
FMD PE L A+ L
Sbjct: 993 MYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNL 1052
Query: 543 LNYLAALN-DDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFV 601
L + A ++ LT LG +A P++ ++ KM+I + C + V ++ A+++ F
Sbjct: 1053 LRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFT 1112
Query: 602 RPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHE------SVQWCYDNFINYRSLM 655
P K AD AK A D DHLT+ N Y +K+ + + +C NF+N SL+
Sbjct: 1113 TPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLL 1172
Query: 656 SADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHL---------ER 706
+ ++V+Q+L +++ S+ TS + N +A T F ++A L +
Sbjct: 1173 TLEDVKQELIKLVKAAGF---SSSTTSTSWEGN--RASQTLSFQEIALLKAVLVAGLYDN 1227
Query: 707 TGHYLTVKDNQV--------------VQLHPSTVLD--HKPEWVLYNEFVLTTKNYIRTC 750
G + K V Q+HPS+V W+LY E + + Y+R
Sbjct: 1228 VGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRET 1287
Query: 751 TDIKP 755
T I P
Sbjct: 1288 TLITP 1292
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 220 bits (561), Expect = 4e-57
Identities = 167/605 (27%), Positives = 290/605 (47%), Gaps = 85/605 (14%)
Query: 137 LPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVAC----TQ 192
LP+ YK+ ++ + ++ G TGSGK+TQ+PQ+ +++ +R C TQ
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHY-----VQRSAYCSIVVTQ 186
Query: 193 PRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLE 252
PR++ A S+A+ ++ E LG VGY + E ++ T L YMT G+LL++ ++ L
Sbjct: 187 PRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLM 246
Query: 253 RYGVIILDEAHERTLATDILMGVLKEVVRQRSD-LKVIVMSATLDAGKFQIYF------- 304
+ II+DE HERT D L+ V+++++R S +KV++MSAT+ +F YF
Sbjct: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
Query: 305 -DNCPLLTIPGRTHPVEIFYTPEPE------------------RDYLEAAIRTVIQ---I 342
+ + + G+ H VE +Y + E +D E A+ + +
Sbjct: 307 MNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDL 366
Query: 343 HMCEE------------EEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYS 390
M E E +L+FL G EI+ + + V +++ PL+S
Sbjct: 367 DMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKR------LQVYPLHS 420
Query: 391 TLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 450
++ ++Q +F P P RK+++STNIAE+S+T+ V +VID + V +
Sbjct: 421 SVALEEQNNVFLSPVPGY------RKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDED 474
Query: 451 IRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSV 510
+SL ++ SK S QR GRAGR G C+RL + + + D+ PE+LR LGS
Sbjct: 475 TNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGST 534
Query: 511 VLQLKKLGIDD--LVHFDFMDPPAPETLMRALELLNYLAAL----------NDDGDLTEL 558
+L++K L + + + + PP + R + LL + AL DG+LT L
Sbjct: 535 ILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFL 594
Query: 559 GSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFA 618
G ++A+ P++ QL K+++ + C +E L I A LS+ F P K+ F+
Sbjct: 595 GRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFS 654
Query: 619 -HIDGDHLTLLNVYHAFKQNHES---------VQWCYDNFINYRSLMSADNVRQQLSRIM 668
D + L+ + +K ++ + W N+I + + + ++L +
Sbjct: 655 GSSKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRI 714
Query: 669 DRFNL 673
+FN+
Sbjct: 715 SQFNM 719
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 192 bits (487), Expect = 1e-48
Identities = 142/468 (30%), Positives = 230/468 (49%), Gaps = 70/468 (14%)
Query: 359 QEEIDEACKRIKREVD----DLGPEVGD-------IKIIPLYSTLPPQQQQRIFEPPPPK 407
+ E+DE + ++D D G + G+ + ++PLYS L P++Q ++F+PPP
Sbjct: 553 EAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEG 612
Query: 408 KQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQ 467
R VV+TN+AETSLTI G+ +V+D G K++ Y+ V S VT +S+ASA
Sbjct: 613 T------RLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASAD 666
Query: 468 QRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDF 527
QRAGRAGRT PG C+RLY+ + + + PEI R + ++LQ+K L ++ +++F F
Sbjct: 667 QRAGRAGRTEPGHCYRLYSSAVF-GDFEQFPPPEITRRPVEDLILQMKALNVEKVINFPF 725
Query: 528 MDPPAPETLMRALELLNYLAALND---------------DGDLTELGSMMAEFPLDPQLA 572
PP+ E L+ A ELL L AL +T LG MA FP+ P+ A
Sbjct: 726 PTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYA 785
Query: 573 KMVIASCDYNCSNEVLSITAMLSVPQCFV---RPTEAKKAADEAKMRFAHID-------- 621
KM+ S + C ++I A ++V + F RP + + K + A +
Sbjct: 786 KMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAG 845
Query: 622 -------GDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIM------ 668
GD + LL A + + Q+C N + Y+++M +R QL+ +
Sbjct: 846 QGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPE 905
Query: 669 -DRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERT---------GHYLTVKDNQV 718
+ F P+ S+ Y +R+ + G +A ++ Y T +
Sbjct: 906 AELFVDPKMQPPTESQVTY--LRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLLDDP 963
Query: 719 VQLHPSTVL-DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQY 765
V +HPS+VL PE+V+Y E V TTK Y++ + ++ +W+ + P Y
Sbjct: 964 VFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSY 1011
Score = 170 bits (430), Expect = 5e-42
Identities = 117/353 (33%), Positives = 190/353 (53%), Gaps = 22/353 (6%)
Query: 29 RDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHS 88
R R R +++ + E + + E E E E +++ A + + PL +
Sbjct: 151 RKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPA-------P 203
Query: 89 AHSTHSTHSAHSTHAGHAGHTSLPQCI-NPFTNLPHTPRYYDILKKRLQLPVWEYKDRFT 147
A S+ + + A LP+ + P +P R ++ ++RL+LP+ +
Sbjct: 204 APSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIP-VNRSPEMQEERLKLPILSEEQVIM 262
Query: 148 DILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVAD 207
+ + H ++ GETGSGKTTQ+PQ+ E S GV T+PRRVAA++++QRVA
Sbjct: 263 EAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGV--TEPRRVAAVAMSQRVAK 320
Query: 208 EMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTL 267
EM++ + V Y IR+E + +T +K+MTDG+LL+E D LL RY V+I+DEAHER++
Sbjct: 321 EMNLSQ-RVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSV 379
Query: 268 ATDILMGVLKEVVRQRS----DLKVIVMSATLDAGKF----QIYFDNCPLLTIPGRTHPV 319
TDIL+G+L +V R+ LK+++MSATL F +++ P++ + R PV
Sbjct: 380 YTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPV 439
Query: 320 EIFYTPE-PERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKR 371
+ + P DY R V +IH G +L+FLTGQ E+ C+R+++
Sbjct: 440 TVHFNKRTPLEDYSGECFRKVCKIHRM-LPAGGILVFLTGQAEVHALCRRLRK 491
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 186 bits (471), Expect = 1e-46
Identities = 141/450 (31%), Positives = 221/450 (49%), Gaps = 47/450 (10%)
Query: 343 HMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFE 402
H C+ G +L+FL G +EI RI + ++ L+S + Q+++ +
Sbjct: 618 HSCDA--GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLK 675
Query: 403 PPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAIS 462
PP A RK+++STNIAETS+T++ VVFVID G K+K ++ V L + IS
Sbjct: 676 NPP------AGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWIS 729
Query: 463 KASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDL 522
KASA QR GRAGR RPG CFRL++ ++ ++ T PE+LR L + L K L +
Sbjct: 730 KASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQT-PELLRMPLQELCLHTKLLAPVNC 788
Query: 523 VHFDFM----DPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIAS 578
DF+ +PP + A+++L + A++ DLTELG +A+ P++P L KMV+ +
Sbjct: 789 PIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCA 848
Query: 579 CDYNCSNEVLSITAMLSVPQCFVRPTEA--KKAADEAKMRF-AHIDGDHLTLLNVYHAFK 635
C + +L+I L+ FV PT+A K+AA + RF A DH+ LL + A+
Sbjct: 849 VVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAW- 907
Query: 636 QNHESVQW----CYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYIN--- 688
Q S W C NF++ ++ +R QL + R RD N
Sbjct: 908 QKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSEN 967
Query: 689 ---IRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDH---------------- 729
++ ALV G + + H++R LT + V+ HP++VL
Sbjct: 968 WAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAI 1027
Query: 730 ---KPEWVLYNEFVLTTK-NYIRTCTDIKP 755
+W++Y+E + IR C+ + P
Sbjct: 1028 KALPTDWLIYDEMTRAHRIANIRCCSAVTP 1057
Score = 142 bits (357), Expect = 2e-33
Identities = 85/206 (41%), Positives = 126/206 (61%), Gaps = 10/206 (4%)
Query: 134 RLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQP 193
R LPV+E ++ I+ ++ ++VGETGSGKTTQIPQ+ ++ P R + CTQP
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCR-IFCTQP 248
Query: 194 RRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAM-NDPLLE 252
RR+AA++VA+RVA E +GQ +GY IR E S KT+L + T+G+LLR M D L
Sbjct: 249 RRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLS 308
Query: 253 RYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTI 312
+I+DE HER +D L+ L++++++ LK+I+ SA LD F YF +CP++ I
Sbjct: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYI 368
Query: 313 PGRTHPVEIFYTPEPERDYLEAAIRT 338
GR P E+ + +LE +RT
Sbjct: 369 QGR--PFEV------KEMFLEDILRT 386
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 182 bits (461), Expect = 1e-45
Identities = 99/201 (49%), Positives = 134/201 (66%), Gaps = 5/201 (2%)
Query: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPK 185
++ IL++R LP WE ++ ++L +HQ V+ G TG GKTTQIPQ+ ++ SL GP
Sbjct: 533 QFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILD--DSLNGPP 590
Query: 186 RGVA---CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLL 242
VA CTQPRR++A+SVA+RVA E +G VGY IR E S+ T L Y T G+LL
Sbjct: 591 EKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL 650
Query: 243 REAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQI 302
R D L+ II+DE HERT +D L+ VLK++V QR L+VI+MSATL+A F
Sbjct: 651 RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSD 710
Query: 303 YFDNCPLLTIPGRTHPVEIFY 323
YF++CP++TIPGRT PV+ F+
Sbjct: 711 YFNSCPVITIPGRTFPVDQFF 731
Score = 169 bits (429), Expect = 7e-42
Identities = 110/336 (32%), Positives = 175/336 (52%), Gaps = 16/336 (4%)
Query: 350 GDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQ 409
G +L+FL G EI ++++ I PL+S+L ++QQ +F PP
Sbjct: 848 GAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPP---- 903
Query: 410 NGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQR 469
A K+++STNIAETS+TID VV+VID G K+K Y+ +ESL T +S+A+A QR
Sbjct: 904 --AGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQR 961
Query: 470 AGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDL-----VH 524
GRAGR G CF L+T Y ++ PEI R L + L++K L + V
Sbjct: 962 KGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVF 1021
Query: 525 FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCS 584
++PP ++L + L L AL D LT LG +A P+D ++ K+++ + C
Sbjct: 1022 SRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCL 1081
Query: 585 NEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQN-----HE 639
+ L+I A L+ FV P + K+ A++ K+ FA + D+L LL Y ++ +
Sbjct: 1082 DPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRA 1141
Query: 640 SVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPR 675
S +C NF++ R L ++++Q + ++ R
Sbjct: 1142 SYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAR 1177
>gi|14670268 RD RNA-binding protein [Homo sapiens]
Length = 380
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/50 (50%), Positives = 38/50 (76%), Gaps = 4/50 (8%)
Query: 14 PSGKKRAGTDGKDRDRDRDRE---DRSKDRDRERDRGDREREREKEKEKE 60
P + R + ++RDRDRDRE DR +DRDRERDR DR+R+R++++E++
Sbjct: 183 PRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDR-DRDRDRDRDRERD 231
Score = 52.8 bits (125), Expect = 1e-06
Identities = 27/45 (60%), Positives = 34/45 (75%), Gaps = 6/45 (13%)
Query: 25 KDRDRDRDRE-----DRSKDRDRERDRGDREREREKEKEKELRAS 64
+DRDRDRDRE DR +DRDRERDR DRER+R++++E R S
Sbjct: 206 RDRDRDRDRERDRDRDRDRDRDRERDR-DRERDRDRDREGPFRRS 249
Score = 44.3 bits (103), Expect = 5e-04
Identities = 29/59 (49%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDRERE---REKEKEKELRA 63
D D + R +DRDRDRDR DR +DRDRERDR DR+RE R + E RA
Sbjct: 201 DRERDRDRDRDRDRERDRDRDRDRDR-DRERDRDRERDR-DRDREGPFRRSDSFPERRA 257
Score = 40.4 bits (93), Expect = 0.007
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 25 KDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKELRASTNAMLI 70
+DRDRDRDRE DR ++RDR+RDR R + E+ N + +
Sbjct: 220 RDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLYV 266
Score = 36.6 bits (83), Expect = 0.094
Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 6/53 (11%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
D G + SG + + + R RDR E R+R+RDR DRER+R+++++++
Sbjct: 167 DWGYEERSGAHSSASPPRSRSRDRSHE-----RNRDRDR-DRERDRDRDRDRD 213
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/48 (56%), Positives = 36/48 (75%), Gaps = 4/48 (8%)
Query: 17 KKRAGTDGKDRDRDRDRE---DRSKDRDRERDRG-DREREREKEKEKE 60
K+R ++RDRDRDRE DR+KDR R R++ DRERERE+E+E+E
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERE 402
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/45 (53%), Positives = 37/45 (82%), Gaps = 2/45 (4%)
Query: 17 KKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
K R+ + K RDR+R+RE +R ++R+RER+R +RERERE+E+E+E
Sbjct: 379 KDRSRSREKSRDRERERERERERERERERER-ERERERERERERE 422
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/50 (46%), Positives = 38/50 (76%), Gaps = 2/50 (4%)
Query: 12 DYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
D + R+ +DR+R+R+RE +R ++R+RER+R +RERERE+E+E+E
Sbjct: 376 DRNKDRSRSREKSRDRERERERERERERERERERER-ERERERERERERE 424
Score = 47.8 bits (112), Expect = 4e-05
Identities = 24/54 (44%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
D D ++R+ KDR R R++ DR ++R+RER+R +RERERE+E+E+E
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER-ERERERERERERE 414
Score = 47.0 bits (110), Expect = 7e-05
Identities = 22/54 (40%), Positives = 41/54 (75%), Gaps = 2/54 (3%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
D +D ++++ ++R+R+R+RE +R ++R+RER+R +RERERE+E+EK+
Sbjct: 376 DRNKDRSRSREKSRDRERERERERERERERERERERERER-EREREREREREKD 428
Score = 46.6 bits (109), Expect = 9e-05
Identities = 23/44 (52%), Positives = 34/44 (77%), Gaps = 1/44 (2%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
K+R + + R+R+R+RE + R+RER+R +REREREKEKE+E
Sbjct: 300 KERQEIEKERRERERERERERERRERERER-EREREREKEKERE 342
Score = 45.4 bits (106), Expect = 2e-04
Identities = 19/36 (52%), Positives = 32/36 (88%), Gaps = 1/36 (2%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+RE ++R+RER+R +RERE+EKE+E+E
Sbjct: 310 RERERERERERERRERERERER-EREREKEKERERE 344
Score = 45.4 bits (106), Expect = 2e-04
Identities = 18/36 (50%), Positives = 33/36 (91%), Gaps = 1/36 (2%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+RE R ++R+RER+R +RE+E+E+E+E+E
Sbjct: 312 RERERERERERRERERERERER-EREKEKERERERE 346
Score = 45.1 bits (105), Expect = 3e-04
Identities = 19/45 (42%), Positives = 34/45 (75%), Gaps = 1/45 (2%)
Query: 17 KKRAGTDGKDRDR-DRDREDRSKDRDRERDRGDREREREKEKEKE 60
++ G K+R +++R +R ++R+RER+R +RERERE+E+E+E
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERRERERERERERERE 336
Score = 43.9 bits (102), Expect = 6e-04
Identities = 16/36 (44%), Positives = 33/36 (91%), Gaps = 1/36 (2%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+R +R ++R+RER+R ++E+ERE+E+E++
Sbjct: 314 RERERERERRERERERERERER-EKEKERERERERD 348
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 32/45 (71%), Gaps = 2/45 (4%)
Query: 16 GKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
GKK + ++ +++R +R ++R+RER +RERERE+E+EKE
Sbjct: 296 GKKEK--ERQEIEKERRERERERERERERREREREREREREREKE 338
Score = 41.2 bits (95), Expect = 0.004
Identities = 20/53 (37%), Positives = 35/53 (66%), Gaps = 12/53 (22%)
Query: 25 KDRDRDRDRE-----------DRSKDRDRERDRGDREREREKEKEKELRASTN 66
++R+R+R+RE DR +DR +ERDR DR+RER++++++E + N
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKERDR-DRDRERDRDRDRERSSDRN 378
Score = 40.8 bits (94), Expect = 0.005
Identities = 17/37 (45%), Positives = 34/37 (91%), Gaps = 2/37 (5%)
Query: 25 KDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+RE +R ++R+RER+R +RERE++K++++E
Sbjct: 399 RERERERERERERERERERERER-EREREKDKKRDRE 434
Score = 40.4 bits (93), Expect = 0.007
Identities = 17/37 (45%), Positives = 33/37 (89%), Gaps = 2/37 (5%)
Query: 25 KDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+RE ++ K+R+RER+R DR+R+R KE++++
Sbjct: 325 REREREREREREKEKERERERER-DRDRDRTKERDRD 360
Score = 38.9 bits (89), Expect = 0.019
Identities = 16/37 (43%), Positives = 33/37 (89%), Gaps = 2/37 (5%)
Query: 25 KDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
++R+R+R+RE +R K+++RER+R +R+R+R++ KE++
Sbjct: 323 REREREREREREREKEKERERER-ERDRDRDRTKERD 358
Score = 36.6 bits (83), Expect = 0.094
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
KK GK ++ E ++R+RER+R RERE+E+E+E
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERE 332
Score = 35.8 bits (81), Expect = 0.16
Identities = 15/34 (44%), Positives = 31/34 (91%), Gaps = 2/34 (5%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKE 58
++R+R+R+RE R ++R+RER++ D++R+RE+++E
Sbjct: 407 RERERERERE-REREREREREK-DKKRDREEDEE 438
Score = 33.5 bits (75), Expect = 0.80
Identities = 16/38 (42%), Positives = 29/38 (76%), Gaps = 2/38 (5%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELR 62
++R+R+R+RE R ++R+RE+D+ R+RE ++E E R
Sbjct: 409 RERERERERE-REREREREKDK-KRDREEDEEDAYERR 444
Score = 33.5 bits (75), Expect = 0.80
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 11/46 (23%)
Query: 28 DRDRDRED-----------RSKDRDRERDRGDREREREKEKEKELR 62
D D DR+D R +DR++E + +R+R+REKE+ +E+R
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIR 547
Score = 33.1 bits (74), Expect = 1.0
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Query: 7 LDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDR---ERDRGDREREREKEKEKELR 62
+++ ED R + +D + + E K+++R E++R +RERERE+E+E+ R
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRER 325
Score = 33.1 bits (74), Expect = 1.0
Identities = 13/39 (33%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Query: 25 KDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKELR 62
++R+R+R+RE +R KD+ R+R+ + + ++ E++LR
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLR 451
Score = 30.8 bits (68), Expect = 5.2
Identities = 15/48 (31%), Positives = 28/48 (58%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREK 55
D +D K G+ + R RDR++E + +RDR+R++ + E R++
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQR 549
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/49 (51%), Positives = 35/49 (71%), Gaps = 5/49 (10%)
Query: 17 KKRAGTDGKDRDRDRDRE-----DRSKDRDRERDRGDREREREKEKEKE 60
K+R +DRD DR+RE DR K+R+RER+ +RERERE+E+E+E
Sbjct: 721 KERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Score = 48.9 bits (115), Expect = 2e-05
Identities = 21/53 (39%), Positives = 39/53 (73%), Gaps = 1/53 (1%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
D D+ ++R ++++R+R+RE+R ++R+RER+R +RERERE+E+ +E
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERER-ERERERERERARE 779
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/38 (60%), Positives = 33/38 (86%), Gaps = 2/38 (5%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELR 62
K+RDR+RDR DR DR+RER+R +R+RE+E+E+E+E R
Sbjct: 721 KERDRERDR-DRDHDRERERER-ERDREKEREREREER 756
Score = 46.6 bits (109), Expect = 9e-05
Identities = 25/66 (37%), Positives = 42/66 (63%), Gaps = 8/66 (12%)
Query: 3 KRHRLDLGEDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRG-------DRERERE 54
+ R+D +D + R ++RDR+R+RE +R +DR+RE++R +RERERE
Sbjct: 661 EERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERERE 720
Query: 55 KEKEKE 60
KE+++E
Sbjct: 721 KERDRE 726
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/36 (63%), Positives = 32/36 (88%), Gaps = 2/36 (5%)
Query: 26 DRDRDRDREDRSKDRDRERDRGDREREREKEKEKEL 61
+R R+RDRE R +DR+RER+R +RER+RE+EKE+EL
Sbjct: 674 ERARERDRE-RERDRERERER-ERERDREREKEREL 707
Score = 43.9 bits (102), Expect = 6e-04
Identities = 21/36 (58%), Positives = 31/36 (86%), Gaps = 2/36 (5%)
Query: 26 DRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
+R+R R+RE +R K+RDRERDR DR+ +RE+E+E+E
Sbjct: 708 ERERAREREREREKERDRERDR-DRDHDRERERERE 742
Score = 38.5 bits (88), Expect = 0.025
Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 13/59 (22%)
Query: 14 PSGKKRAGTDGKDRDRDRDRE------------DRSKDRDRERDRGDREREREKEKEKE 60
PS R + +RD RE +R+++RDRER+R DRERERE+E+E++
Sbjct: 641 PSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER-DRERERERERERD 698
Score = 38.5 bits (88), Expect = 0.025
Identities = 17/44 (38%), Positives = 33/44 (75%), Gaps = 8/44 (18%)
Query: 25 KDRDRDRDRE-------DRSKDRDRERDRG-DREREREKEKEKE 60
+DR+R+++RE +R ++R++ERDR DR+R+ ++E+E+E
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Score = 38.5 bits (88), Expect = 0.025
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 4 RHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELR 62
R RL + Y ++R R R+ DR D KD R RDR DR RERE+E+E++ R
Sbjct: 1296 RDRLQERDRYEHDRERERERRDTRQREWDR-DADKDWPRNRDR-DRLRERERERERDKR 1352
Score = 38.5 bits (88), Expect = 0.025
Identities = 20/46 (43%), Positives = 33/46 (71%), Gaps = 4/46 (8%)
Query: 17 KKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKEL 61
++R T ++ DRD D++ R++DRDR R+R ERERE++K ++L
Sbjct: 1313 RERRDTRQREWDRDADKDWPRNRDRDRLRER---ERERERDKRRDL 1355
Score = 37.7 bits (86), Expect = 0.042
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPP 76
++RA K+R+R RD ED+ K RD R++ + RE ++ + + G P
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 77 LKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINP 117
+ S HS S + +S + H L Q + P
Sbjct: 834 PRQSPKRRREHSPDS----DAYNSGDDKNEKHRLLSQVVRP 870
Score = 36.2 bits (82), Expect = 0.12
Identities = 18/53 (33%), Positives = 34/53 (64%), Gaps = 11/53 (20%)
Query: 25 KDRDRDRDRE-----DRSKDRDRERDR------GDREREREKEKEKELRASTN 66
++R+R+R+RE +R+++RD+ER+R D+ R+ +EK +E+R N
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN 812
Score = 34.3 bits (77), Expect = 0.47
Identities = 19/44 (43%), Positives = 33/44 (75%), Gaps = 4/44 (9%)
Query: 19 RAGT-DGKDRDRDRDREDRSKDRDRERDRGD-REREREKEKEKE 60
R+G+ D +DR ++RDR + DR+RER+R D R+RE +++ +K+
Sbjct: 1289 RSGSFDSRDRLQERDRYEH--DRERERERRDTRQREWDRDADKD 1330
Score = 34.3 bits (77), Expect = 0.47
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 10/58 (17%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDR-------GDREREREKEKE 58
D +D+P + R ++R+R+RD+ +D DRER+R DR+R+R++ E
Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKR---RDLDRERERLISDSVERDRDRDRDRTFE 1380
Score = 33.5 bits (75), Expect = 0.80
Identities = 14/47 (29%), Positives = 28/47 (59%)
Query: 13 YPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
+ S + R+ +DR +RD D+++D ER G+R+R +E+++
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQ 639
Score = 31.6 bits (70), Expect = 3.0
Identities = 14/40 (35%), Positives = 25/40 (62%)
Query: 26 DRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRAST 65
+RDR +R++R + RD +R ER+R +E++ R S+
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSS 643
Score = 31.6 bits (70), Expect = 3.0
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 11 EDYPSGKKRAGTDGKDRD-RDRDREDRSKDRDRERDRGDREREREKEK 57
+D S R + DR R S+DR +ERDR + +RERE+E+
Sbjct: 1268 QDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERER 1315
Score = 30.4 bits (67), Expect = 6.7
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 8 DLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNA 67
D D ++R +D +RDRDRDR DR+ + + E + E E E++L +++
Sbjct: 1350 DKRRDLDRERERLISDSVERDRDRDR-DRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408
Query: 68 MLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAG 104
S L + S T+ + S AG
Sbjct: 1409 ---SLALDKERMDKDLGSVQGFEETNKSERTESLEAG 1442
>gi|125988409 RED protein [Homo sapiens]
Length = 557
Score = 50.1 bits (118), Expect = 8e-06
Identities = 25/47 (53%), Positives = 37/47 (78%), Gaps = 2/47 (4%)
Query: 14 PSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKE 60
P K+R ++RDR+RDR DR ++R+RERDR +RERER++E+E+E
Sbjct: 333 PRDKERERYRERERDRERDR-DRDRERERERDR-ERERERDREREEE 377
Score = 46.6 bits (109), Expect = 9e-05
Identities = 27/61 (44%), Positives = 41/61 (67%), Gaps = 10/61 (16%)
Query: 8 DLGEDYPSGKK--------RAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKE 58
D+G+ PS K R +DR+RDRDR+ +R ++RDRER+R +R+RERE+EK+
Sbjct: 321 DIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERER-ERDREREEEKK 379
Query: 59 K 59
+
Sbjct: 380 R 380
>gi|10190682 chromobox homolog 8 [Homo sapiens]
Length = 389
Score = 50.1 bits (118), Expect = 8e-06
Identities = 24/35 (68%), Positives = 32/35 (91%), Gaps = 2/35 (5%)
Query: 25 KDRDRDRDREDRSKDRDRERDRGDREREREKEKEK 59
+DRDRDRDR DR +DR+RER+R +RERERE+E+E+
Sbjct: 148 RDRDRDRDR-DRERDRERERER-ERERERERERER 180
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/41 (60%), Positives = 30/41 (73%), Gaps = 6/41 (14%)
Query: 27 RDRDRDREDRSKDRDRERDR-GDREREREKEKEKELRASTN 66
RDRDRDR DRDRERDR +RERERE+E+E+E T+
Sbjct: 148 RDRDRDR-----DRDRERDRERERERERERERERERERGTS 183
Score = 39.7 bits (91), Expect = 0.011
Identities = 19/31 (61%), Positives = 24/31 (77%), Gaps = 1/31 (3%)
Query: 31 RDREDRSKDRDRERDR-GDREREREKEKEKE 60
R R +DRDR+RDR DRERERE+E+E+E
Sbjct: 143 RAEAPRDRDRDRDRDRERDRERERERERERE 173
Score = 34.3 bits (77), Expect = 0.47
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 13/61 (21%)
Query: 14 PSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDR------------GDREREREKEKEKE 60
P + R ++RDR+R+RE +R ++R+RER+R GD ++R + KE
Sbjct: 147 PRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRKE 206
Query: 61 L 61
L
Sbjct: 207 L 207
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 8/78 (10%)
Query: 6 RLDLGEDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKEL--- 61
RL + E+ ++R ++R+ DR+RE +R ++R++ER++ ++EREREKE+E+EL
Sbjct: 226 RLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKEREREKERERELERQ 284
Query: 62 ---RASTNAMLISAGLPP 76
RA +L + L P
Sbjct: 285 REQRAREKELLAAKALEP 302
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 8/78 (10%)
Query: 6 RLDLGEDYPSGKKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKEL--- 61
RL + E+ ++R ++R+ DR+RE +R ++R++ER++ ++EREREKE+E+EL
Sbjct: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKEREREKERERELERQ 388
Query: 62 ---RASTNAMLISAGLPP 76
RA +L + L P
Sbjct: 389 REQRAREKELLAAKALEP 406
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 48.1 bits (113), Expect = 3e-05
Identities = 22/45 (48%), Positives = 36/45 (80%), Gaps = 2/45 (4%)
Query: 17 KKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
K+R +D++R++DRE D+ KDR+RER++ + E++R+KEKEKE
Sbjct: 409 KERGKNKDRDKEREKDREKDKEKDREREREK-EHEKDRDKEKEKE 452
Score = 46.6 bits (109), Expect = 9e-05
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 10 GEDYPSGKKRAGTDGKDRDRDRDRE---DRSKDRDRERDRG-DREREREKEKEKELRAST 65
G++ K+R KD+++DR+RE + KDRD+E+++ D+E+EREK++ KE+
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 66 NAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHT 109
S PP + S S S+ S S+ + T
Sbjct: 472 KKDKKSR-TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514
Score = 43.9 bits (102), Expect = 6e-04
Identities = 19/39 (48%), Positives = 34/39 (87%), Gaps = 4/39 (10%)
Query: 25 KDRDRDRDREDRSKDRDRERDRG---DREREREKEKEKE 60
K++DR+++RE R K+R++E++RG DR++EREK++EK+
Sbjct: 391 KEKDREKERE-REKEREKEKERGKNKDRDKEREKDREKD 428
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 13/72 (18%)
Query: 2 SKRHRLDLGEDYPSG-KKRAGTDGKDRDRDRDRED---------RSKDRDRERDRG---D 48
S+ H D +D K++ KDR+++R+RE ++KDRD+ER++ D
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 428
Query: 49 REREREKEKEKE 60
+E++RE+E+EKE
Sbjct: 429 KEKDREREREKE 440
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTN 66
K R+ + +D+ +D + + K+R +E+DR ++EREREKE+EKE N
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDR-EKEREREKEREKEKERGKN 414
Score = 33.9 bits (76), Expect = 0.61
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 15/59 (25%)
Query: 17 KKRAGTDGKDRDRDRDRE---DRSKDRDRERD------------RGDREREREKEKEKE 60
++R+ + K R + R+R RS RD+ +D DRE+ERE+EKE+E
Sbjct: 348 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 406
Score = 30.8 bits (68), Expect = 5.2
Identities = 14/55 (25%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 14 PSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAM 68
PS + R + KD+ R+++R+ S+ R+RER R+ +++ +++L ++ ++
Sbjct: 523 PSPRSR---NKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSL 574
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 48.1 bits (113), Expect = 3e-05
Identities = 22/45 (48%), Positives = 36/45 (80%), Gaps = 2/45 (4%)
Query: 17 KKRAGTDGKDRDRDRDRE-DRSKDRDRERDRGDREREREKEKEKE 60
K+R +D++R++DRE D+ KDR+RER++ + E++R+KEKEKE
Sbjct: 293 KERGKNKDRDKEREKDREKDKEKDREREREK-EHEKDRDKEKEKE 336
Score = 46.6 bits (109), Expect = 9e-05
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 10 GEDYPSGKKRAGTDGKDRDRDRDRE---DRSKDRDRERDRG-DREREREKEKEKELRAST 65
G++ K+R KD+++DR+RE + KDRD+E+++ D+E+EREK++ KE+
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355
Query: 66 NAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHT 109
S PP + S S S+ S S+ + T
Sbjct: 356 KKDKKSR-TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398
Score = 43.9 bits (102), Expect = 6e-04
Identities = 19/39 (48%), Positives = 34/39 (87%), Gaps = 4/39 (10%)
Query: 25 KDRDRDRDREDRSKDRDRERDRG---DREREREKEKEKE 60
K++DR+++RE R K+R++E++RG DR++EREK++EK+
Sbjct: 275 KEKDREKERE-REKEREKEKERGKNKDRDKEREKDREKD 312
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 13/72 (18%)
Query: 2 SKRHRLDLGEDYPSG-KKRAGTDGKDRDRDRDRED---------RSKDRDRERDRG---D 48
S+ H D +D K++ KDR+++R+RE ++KDRD+ER++ D
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 312
Query: 49 REREREKEKEKE 60
+E++RE+E+EKE
Sbjct: 313 KEKDREREREKE 324
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 17 KKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTN 66
K R+ + +D+ +D + + K+R +E+DR ++EREREKE+EKE N
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDR-EKEREREKEREKEKERGKN 298
Score = 33.9 bits (76), Expect = 0.61
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 15/59 (25%)
Query: 17 KKRAGTDGKDRDRDRDRE---DRSKDRDRERD------------RGDREREREKEKEKE 60
++R+ + K R + R+R RS RD+ +D DRE+ERE+EKE+E
Sbjct: 232 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 290
Score = 30.8 bits (68), Expect = 5.2
Identities = 14/55 (25%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 14 PSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAM 68
PS + R + KD+ R+++R+ S+ R+RER R+ +++ +++L ++ ++
Sbjct: 407 PSPRSR---NKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSL 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,001,192
Number of Sequences: 37866
Number of extensions: 1430416
Number of successful extensions: 12703
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 7608
Number of HSP's gapped (non-prelim): 2726
length of query: 795
length of database: 18,247,518
effective HSP length: 110
effective length of query: 685
effective length of database: 14,082,258
effective search space: 9646346730
effective search space used: 9646346730
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.