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Search of human proteins with 67782315
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
sapiens]
(706 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap... 1453 0.0
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap... 1307 0.0
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap... 1290 0.0
gi|92859670 solute carrier family 6 (neurotransmitter transporte... 633 0.0
gi|134304856 solute carrier family 6, member 7 [Homo sapiens] 621 e-178
gi|6005715 solute carrier family 6 (amino acid transporter), mem... 525 e-149
gi|7657587 solute carrier family 6 (neurotransmitter transporter... 518 e-147
gi|188528618 solute carrier family 6 (neurotransmitter transport... 518 e-147
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi... 515 e-146
gi|21361581 solute carrier family 6 (neurotransmitter transporte... 514 e-145
gi|171184408 solute carrier family 6 (neurotransmitter transport... 505 e-143
gi|171184406 solute carrier family 6 (neurotransmitter transport... 505 e-143
gi|171184404 solute carrier family 6 (neurotransmitter transport... 505 e-143
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa... 498 e-140
gi|4507043 solute carrier family 6 member 4 [Homo sapiens] 487 e-137
gi|4557046 solute carrier family 6 member 2 [Homo sapiens] 479 e-135
gi|4507041 solute carrier family 6 (neurotransmitter transporter... 477 e-134
gi|197276623 solute carrier family 6 (neurotransmitter transport... 469 e-132
gi|54607094 solute carrier family 6 (neurotransmitter transporte... 469 e-132
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa... 423 e-118
gi|51468073 solute carrier family 6, member 19 [Homo sapiens] 392 e-109
gi|194018524 solute carrier family 6, member 18 [Homo sapiens] 365 e-100
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s... 364 e-100
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s... 302 6e-82
gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 298 9e-81
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s... 279 7e-75
gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 223 4e-58
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ... 210 4e-54
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s... 169 8e-42
gi|197276625 solute carrier family 6 (neurotransmitter transport... 159 6e-39
>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
sapiens]
Length = 706
Score = 1453 bits (3762), Expect = 0.0
Identities = 706/706 (100%), Positives = 706/706 (100%)
Query: 1 MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKV 60
MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKV
Sbjct: 1 MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKV 60
Query: 61 WHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL 120
WHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL
Sbjct: 61 WHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL 120
Query: 121 GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG 180
GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG
Sbjct: 121 GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG 180
Query: 181 VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN 240
VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN
Sbjct: 181 VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN 240
Query: 241 GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV 300
GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV
Sbjct: 241 GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV 300
Query: 301 VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV 360
VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV
Sbjct: 301 VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV 360
Query: 361 WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF 420
WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF
Sbjct: 361 WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF 420
Query: 421 MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL 480
MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL
Sbjct: 421 MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL 480
Query: 481 VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS 540
VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS
Sbjct: 481 VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS 540
Query: 541 CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY 600
CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY
Sbjct: 541 CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY 600
Query: 601 NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE 660
NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE
Sbjct: 601 NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE 660
Query: 661 HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI 706
HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
Sbjct: 661 HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI 706
>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
sapiens]
Length = 652
Score = 1307 bits (3383), Expect = 0.0
Identities = 646/706 (91%), Positives = 649/706 (91%), Gaps = 54/706 (7%)
Query: 1 MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKV 60
MSGGDTRAAIARPRMAAAHG P + ++P
Sbjct: 1 MSGGDTRAAIARPRMAAAHG----------------------PVAPSSPE---------- 28
Query: 61 WHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL 120
QNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL
Sbjct: 29 ----------------------QNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGL 66
Query: 121 GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG 180
GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG
Sbjct: 67 GNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKG 126
Query: 181 VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN 240
VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN
Sbjct: 127 VGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTN 186
Query: 241 GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV 300
GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV
Sbjct: 187 GSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLV 246
Query: 301 VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV 360
VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV
Sbjct: 247 VFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKV 306
Query: 361 WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF 420
WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF
Sbjct: 307 WGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF 366
Query: 421 MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL 480
MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL
Sbjct: 367 MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETL 426
Query: 481 VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS 540
VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS
Sbjct: 427 VTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVIS 486
Query: 541 CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY 600
CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY
Sbjct: 487 CIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITY 546
Query: 601 NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE 660
NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE
Sbjct: 547 NHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLE 606
Query: 661 HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI 706
HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
Sbjct: 607 HRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI 652
>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
sapiens]
Length = 633
Score = 1290 bits (3339), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 84 NGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYF 143
NGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYF
Sbjct: 11 NGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYF 70
Query: 144 IMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIA 203
IMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIA
Sbjct: 71 IMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIA 130
Query: 204 FYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTS 263
FYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTS
Sbjct: 131 FYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTS 190
Query: 264 PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFP 323
PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFP
Sbjct: 191 PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFP 250
Query: 324 YVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMA 383
YVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMA
Sbjct: 251 YVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMA 310
Query: 384 SYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVA 443
SYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVA
Sbjct: 311 SYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVA 370
Query: 444 YPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLG 503
YPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLG
Sbjct: 371 YPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLG 430
Query: 504 VAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMM 563
VAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMM
Sbjct: 431 VAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMM 490
Query: 564 LGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLC 623
LGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLC
Sbjct: 491 LGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLC 550
Query: 624 IPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPSPEDGFEVQPL 683
IPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPSPEDGFEVQPL
Sbjct: 551 IPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPSPEDGFEVQPL 610
Query: 684 HPDKAQIPIVGSNGSSRLQDSRI 706
HPDKAQIPIVGSNGSSRLQDSRI
Sbjct: 611 HPDKAQIPIVGSNGSSRLQDSRI 633
>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
glycine), member 5 [Homo sapiens]
Length = 797
Score = 633 bits (1632), Expect = 0.0
Identities = 300/621 (48%), Positives = 424/621 (68%), Gaps = 25/621 (4%)
Query: 73 LMAQHSLAMAQNGAVPSEATKRDQ----NLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPY 128
++A + G+V + AT+ D+ N RGNW ++++F+L+ VGYAVGLGNVWRFPY
Sbjct: 160 VLATDGITSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPY 219
Query: 129 LCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVV 188
L ++NGGGAF+ PY +ML G+P+FF+E+S GQFASQG + VW+ P +G G M+++
Sbjct: 220 LAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLII 279
Query: 189 STYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAG----VLDASNLTNGSR- 243
S I IYYNV+IC +Y F+S VLPW CNNPWNT +C +LD+ +++ +
Sbjct: 280 SVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKI 339
Query: 244 ------------PAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLL 291
P N + N + S SEEY++ +VLK+S I GE+R PL
Sbjct: 340 QIKNSTFCMTAYPNVTMVNFTSQANKTF--VSGSEEYFKYFVLKISAGIEYPGEIRWPLA 397
Query: 292 GCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQ 351
CL ++W++V+ L +G+K+SGKVVYFTATFPYVVL IL +RGVTL GA GI Y++TP+
Sbjct: 398 LCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPK 457
Query: 352 WDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAG 411
W+K+ +A VW DAA+QIF+SL AWGGLIT++SYNKFHNNCYRD++I++ TN ATS++AG
Sbjct: 458 WEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAG 517
Query: 412 FVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLG 471
FVIFS++GFMAN V++ VAD GPG+AFV YPEALT LP+SP W+++FF ML+ LGL
Sbjct: 518 FVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLD 577
Query: 472 TQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYA 531
T F +ET+VT+I DE +++ K TLG + F++G P+ +Q GIY L+D YA
Sbjct: 578 TMFATIETIVTSISDEF-PKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYA 636
Query: 532 ASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFT 591
AS++LV+I+ V I Y+YG + + +DI+MM+GF P +F+++CW FV+P I+ FIL F+
Sbjct: 637 ASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFS 696
Query: 592 VIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPS 651
Q++P+TY Y+YP W++ +G+LM SV+ IP+ + ++ G ++RLK P
Sbjct: 697 FYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPG-RFIERLKLVCSPQ 755
Query: 652 RDWGPALLEHRTGRYAPTIAP 672
DWGP L +HR RY I P
Sbjct: 756 PDWGPFLAQHRGERYKNMIDP 776
>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
Length = 636
Score = 621 bits (1602), Expect = e-178
Identities = 301/577 (52%), Positives = 412/577 (71%), Gaps = 18/577 (3%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
RGNW +++F+L+ +GY VGLGNVWRFPY Y NGGGAF+ PYF+ML CGIPLFF+ELS
Sbjct: 37 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELS 96
Query: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
GQF+S G L VW+ISP+FKG G M+++ + IYYN++I +Y F+S+T LPW +
Sbjct: 97 LGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEH 156
Query: 220 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL--S 277
C N WNT C L+ +G+ ALP NL+ + SPSEEYW YVL + S
Sbjct: 157 CGNWWNTELC---LEHRVSKDGN--GALPLNLTCTV-------SPSEEYWSRYVLHIQGS 204
Query: 278 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 337
IG+ GE+R L CL ++W++VFLC+++GVKSSGKVVYFTATFPY++L +L VRGVTL
Sbjct: 205 QGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTL 264
Query: 338 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 397
GA+ GI +YLTPQ+ +L +KVW +AA QIFYSLG +GGL+T ASYN FH N YRD+
Sbjct: 265 PGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTF 324
Query: 398 IISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 457
I+++ N TS+ AGF IFS+LG+M+ LGV V +VA GPGLAFV YP+A+T+LP+SP W
Sbjct: 325 IVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFW 384
Query: 458 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLG-VAVAGFLLGIPLT 516
S LFFFML+ LGL +QF LET+VTA+ DE + L+ K V G + VA +L+G+ LT
Sbjct: 385 SFLFFFMLLTLGLDSQFAFLETIVTAVTDEF--PYYLRPKKAVFSGLICVAMYLMGLILT 442
Query: 517 SQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICW 576
+ G+YWL+L+D+Y+ASF L+V+ C+A+ +YG + + +DI MMLGF P L+F+ CW
Sbjct: 443 TDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACW 502
Query: 577 RFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTD 636
F+SPA + ++V+++++YQP Y Y++P WA +G LM L S L IP + + R +
Sbjct: 503 LFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREE 562
Query: 637 GDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS 673
G +L +RL+ A++P+ DWGP+L E+RTG Y T+A S
Sbjct: 563 G-SLWERLQQASRPAMDWGPSLEENRTGMYVATLAGS 598
>gi|6005715 solute carrier family 6 (amino acid transporter), member
14 [Homo sapiens]
Length = 642
Score = 525 bits (1353), Expect = e-149
Identities = 266/607 (43%), Positives = 390/607 (64%), Gaps = 22/607 (3%)
Query: 93 KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIP 152
+ D+N RGNW + +++L+ +GYAVGLGNVWRFPYL Y NGGGAF+ PY IML G+P
Sbjct: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
Query: 153 LFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMT 212
LFF+E S GQFAS G + VWRI P+F+GVG M+++S ++ IYYNV+I + YY F+S
Sbjct: 89 LFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQ 148
Query: 213 HVLPWAYCNNPWNTHDC--AGVLDASNLT--NGSRPAALPSNLS--HLLNHSLQRTS--- 263
LPW C++ W+ +C + ++ N++ N + N S + N + S
Sbjct: 149 SELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIY 207
Query: 264 -----PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYF 318
PSE+YW L+ S + G + L CL ++WL+V L +G+KSSGKVVYF
Sbjct: 208 QPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYF 267
Query: 319 TATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQ--WDKILEAKVWGDAASQIFYSLGCAW 376
TA FPYVVL IL VRG TLEGA GI YY+ Q + K+ EA+VW DAA+QIFYSL AW
Sbjct: 268 TALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAW 327
Query: 377 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 436
GGL+ ++SYNKF NNC+ D++++ +TNC TSV+AGF IFSILG MA+ G +VS+V G
Sbjct: 328 GGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSG 387
Query: 437 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK 496
LAF+AYPEAL LP P WS+LFFFML+ LGL +QF +ET+ T I D + + + +
Sbjct: 388 FDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQD-LFPKVMKKM 446
Query: 497 KTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNY 556
+ +TLG + FLLG+ +QAGIYW+ L+D++ A + +++ + + V I++IYG +
Sbjct: 447 RVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRF 506
Query: 557 FQDIQMMLGFPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG 613
+D +MM+G +F ++ CW ++P ++ I +++++Q+ Y YP W VA+G
Sbjct: 507 IEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
Query: 614 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS 673
+ M + ++ IP+ A+ ++ + G+ + QRL + +P+ +WGP L +HR RY + P
Sbjct: 567 WCMIVFCIIWIPIMAIIKIIQAKGN-IFQRLISCCRPASNWGPYLEQHRGERYKDMVDPK 625
Query: 674 PEDGFEV 680
E E+
Sbjct: 626 KEADHEI 632
>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
GABA), member 11 [Homo sapiens]
Length = 632
Score = 518 bits (1334), Expect = e-147
Identities = 254/580 (43%), Positives = 374/580 (64%), Gaps = 23/580 (3%)
Query: 82 AQNGAVPSE--ATKRDQNL-KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAF 138
+ GA P+ KRD+ + +RG+W N++EFVL+ G +GLGNVWRFPYLCY+NGGGAF
Sbjct: 29 SSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF 88
Query: 139 MFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYN 197
+ PY + I CGIP+FF+E + GQF S+G + WR + P+F+G+GY V+ ++ +YY
Sbjct: 89 LIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYI 148
Query: 198 VVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNH 257
+++ A +Y + T LPWA C + WNT +C + SN SH+
Sbjct: 149 IILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLN-----------VSNYSHV--- 194
Query: 258 SLQR-TSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVV 316
SLQ TSP E+W VL +SD I + G +R L CL +W + + C+ +G KS+GKVV
Sbjct: 195 SLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVV 254
Query: 317 YFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAW 376
Y TATFPY++L IL +RGVTL GA +GI +YL P ++ + +VW DA +QIF+S
Sbjct: 255 YVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICL 314
Query: 377 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 436
G L + SYN ++NNCYRD +++ N TS AGF IFS+LGFMA GV ++ VA+ G
Sbjct: 315 GCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESG 374
Query: 437 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWIL-Q 495
PGLAF+AYP+A+T++P+SPLW+ LFF MLI LGL +QF +E+LVTA+VD +
Sbjct: 375 PGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGY 434
Query: 496 KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHR 554
++ + L ++V + LG+ + ++ G+Y L D+YAAS L+ ++ C+ I ++YG
Sbjct: 435 RRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSN 494
Query: 555 NYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIG 613
++ +I+ M+G+ PP + CW ++P I I +F +I+Y+P+ YN+ Y YP W IG
Sbjct: 495 RFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIG 554
Query: 614 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 653
+LMALSS+LCIPL+ + +T+G TL ++L+ T PS D
Sbjct: 555 WLMALSSMLCIPLWICITVWKTEG-TLPEKLQKLTTPSTD 593
>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
GABA), member 1 [Homo sapiens]
Length = 599
Score = 518 bits (1333), Expect = e-147
Identities = 249/555 (44%), Positives = 364/555 (65%), Gaps = 23/555 (4%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
R W + +F+++ VGYA+GLGNVWRFPYLC +NGGGAF+ PYF+ LIF G+PLF +E S
Sbjct: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
Query: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
GQ+ S G LGVW+++PMFKGVG V+S ++ IYY V+I A YY ++S T LPW
Sbjct: 104 LGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQ 163
Query: 220 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDD 279
C+NPWNT C N TN TS E+W + +++D
Sbjct: 164 CDNPWNTDRCFSNYSMVNTTN--------------------MTSAVVEFWERNMHQMTDG 203
Query: 280 IGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEG 339
+ G++R PL L ++W++V+ C+ +GV +GKVVYF+AT+PY++L ILF RGVTL G
Sbjct: 204 LDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPG 263
Query: 340 AFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVII 399
A +GI++Y+TP + K+ +++VW DAA+QIF+S G G LI + SYN FHNN YRDS+I+
Sbjct: 264 AKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIV 323
Query: 400 SITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSL 459
N TS++AGFVIFSI+GFMA+ ++ VA GPGLAF+AYPEA+T LPISPLW++
Sbjct: 324 CCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAI 383
Query: 460 LFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQA 519
LFF ML++LG+ +QFC +E +TA+VDE +++ ++ V + +L+G+ +Q
Sbjct: 384 LFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIA-AVCIISYLIGLSNITQG 442
Query: 520 GIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRF 578
GIY L D Y+AS SL+ + CV+I + YG ++ +IQ M+G P +++++CW F
Sbjct: 443 GIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSF 502
Query: 579 VSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGD 638
+P I+ + +F+ +Q P+T +Y +P W +G+LMALSS++ IP Y + G
Sbjct: 503 FTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKG- 561
Query: 639 TLLQRLKNATKPSRD 653
+L QR++ +PS D
Sbjct: 562 SLKQRIQVMVQPSED 576
>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
sapiens]
Length = 635
Score = 515 bits (1327), Expect = e-146
Identities = 249/566 (43%), Positives = 364/566 (64%), Gaps = 13/566 (2%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
R W Q++F+++ VG+AVGLGNVWRFPYLCY+NGGG F+ PY ++ + GIP+FF+E+S
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
GQF G + VW I P+FKG+GY MV+ Y YY +V+ FYY S T LPWA
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 220 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDD 279
C + WNT DC + + N S +NL+ + R SP E+W VL+LS
Sbjct: 172 CGHTWNTPDCVEIFRHEDCANASL-----ANLT--CDQLADRRSPVIEFWENKVLRLSGG 224
Query: 280 IGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEG 339
+ G + + CL W++V+ C+ +GVKS+GK+VYFTATFPYVVL +L VRGV L G
Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPG 284
Query: 340 AFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVII 399
A DGI+YYL P W K+ +VW DA +QIF+S G L + SYN+F+NNCY+D++I+
Sbjct: 285 ALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIIL 344
Query: 400 SITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSL 459
++ N TS +AGFV+FSILGFMA GV +S+VA+ GPGLAF+AYP A+TL+P++PLW+
Sbjct: 345 ALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAA 404
Query: 460 LFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVA-GFLLGIPLTSQ 518
LFFFML+LLGL +QF +E +T ++D + + + + +++ + A F++ + + +
Sbjct: 405 LFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTD 464
Query: 519 AGIYWLLLMDNYAASFSLVVISCIM-CVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWR 577
G+Y L D Y+AS + ++ CV + ++YG + DI M+G+ P + + CW
Sbjct: 465 GGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWS 524
Query: 578 FVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTD 636
F +P + I +F V+ Y+P+ YN+ Y YP W A+G+ ALSS+LC+PL+ + L R
Sbjct: 525 FFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAK 584
Query: 637 GDTLLQRLKNATKPSRDWGPALLEHR 662
G T+ +R ++ T+P WG LE+R
Sbjct: 585 G-TMAERWQHLTQPI--WGLHHLEYR 607
>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
GABA), member 13 [Homo sapiens]
Length = 602
Score = 514 bits (1323), Expect = e-145
Identities = 250/570 (43%), Positives = 364/570 (63%), Gaps = 24/570 (4%)
Query: 90 EATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFC 149
E + D L+RG+W N++EFVL+ G +GLGNVWRFPYLCY+NGGGAF PY + L C
Sbjct: 22 EKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTC 81
Query: 150 GIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFF 208
GIP+F +E + GQ+ SQG + WR I P+F+G+GY ++ + +YY +V+ A +Y F
Sbjct: 82 GIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLF 141
Query: 209 SSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEY 268
SS T LPW C + WNT C + NG+ A TSP E+
Sbjct: 142 SSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENA---------------TSPVIEF 186
Query: 269 WRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLT 328
W VLK+SD I + G +R L CL ++W++ + C+ +GVKS+GKVVYFTATFPY++L
Sbjct: 187 WERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLV 246
Query: 329 ILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKF 388
+L +RGVTL GA GI +YL P ++ + +VW DA +QIF+S G L + SYNK+
Sbjct: 247 VLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKY 306
Query: 389 HNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEAL 448
HNNCYRD + + N TS AGF IFSILGFM+ GV +S VA+ GPGLAF+AYP A+
Sbjct: 307 HNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAV 366
Query: 449 TLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKT---YVTLGVA 505
+LP SPLW+ FFFM++LLGL +QF +E+LVTA+VD + + +KK + LGV+
Sbjct: 367 VMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPH--VFRKKNRREVLILGVS 424
Query: 506 VAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMML 564
V FL+G+ + ++ G+Y L D YAAS L+ ++ + + ++YG + ++ +I+ M+
Sbjct: 425 VVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMI 484
Query: 565 GFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYN-HYQYPGWAVAIGFLMALSSVLC 623
G+ P + CW F++PA+ +F++I+Y P+TYN Y YP W A+G+L+ALSS++C
Sbjct: 485 GYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVC 544
Query: 624 IPLYAMFRLCRTDGDTLLQRLKNATKPSRD 653
IP ++++RL G +R++ P+ D
Sbjct: 545 IPAWSLYRLGTLKG-PFRERIRQLMCPAED 573
>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 505 bits (1300), Expect = e-143
Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)
Query: 87 VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 141
VP E K DQ + RG W N++EFVL+ G +GLGNVWRFPYLCY+NGGGAF P
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 142 YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 200
YFI CGIP+FF+E++ GQ+ SQG + WR I P+F+G+G +V+ +Y+ +YY +++
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 201 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 260
A +Y FSS T LPW CNN WNT C L+ S G+ N
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
Query: 261 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 320
TSP E+W VL ++ I + G +R L CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
Query: 321 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 380
TFPY++L IL +RGVTL GA+ GI+YYL P ++ + +VW DA +QIF+S G L
Sbjct: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
Query: 381 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 440
+ SYNK+HNNCY+D + + N ATS AGFV+FSILGFM+ GV +S VA+ GPGLA
Sbjct: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
Query: 441 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 499
F+A+P+A+T++P+S LWS LFF MLI LGL +QF +E LVTA +D + ++
Sbjct: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
Query: 500 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 558
+ L +AV +L+G+ L ++ G+Y L D YA+S L+ +S V I ++YG ++
Sbjct: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
Query: 559 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 617
+I+ M+G+ P +I W F++P + +F++ +Y P+ YN+ Y YP W +IG+ +A
Sbjct: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
Query: 618 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 650
LSS++C+PL+ + L +T G +RL+ P
Sbjct: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 505 bits (1300), Expect = e-143
Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)
Query: 87 VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 141
VP E K DQ + RG W N++EFVL+ G +GLGNVWRFPYLCY+NGGGAF P
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 142 YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 200
YFI CGIP+FF+E++ GQ+ SQG + WR I P+F+G+G +V+ +Y+ +YY +++
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 201 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 260
A +Y FSS T LPW CNN WNT C L+ S G+ N
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
Query: 261 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 320
TSP E+W VL ++ I + G +R L CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
Query: 321 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 380
TFPY++L IL +RGVTL GA+ GI+YYL P ++ + +VW DA +QIF+S G L
Sbjct: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
Query: 381 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 440
+ SYNK+HNNCY+D + + N ATS AGFV+FSILGFM+ GV +S VA+ GPGLA
Sbjct: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
Query: 441 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 499
F+A+P+A+T++P+S LWS LFF MLI LGL +QF +E LVTA +D + ++
Sbjct: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
Query: 500 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 558
+ L +AV +L+G+ L ++ G+Y L D YA+S L+ +S V I ++YG ++
Sbjct: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
Query: 559 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 617
+I+ M+G+ P +I W F++P + +F++ +Y P+ YN+ Y YP W +IG+ +A
Sbjct: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
Query: 618 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 650
LSS++C+PL+ + L +T G +RL+ P
Sbjct: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 505 bits (1300), Expect = e-143
Identities = 251/573 (43%), Positives = 363/573 (63%), Gaps = 24/573 (4%)
Query: 87 VPSEATKRDQNLK-----RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 141
VP E K DQ + RG W N++EFVL+ G +GLGNVWRFPYLCY+NGGGAF P
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 142 YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 200
YFI CGIP+FF+E++ GQ+ SQG + WR I P+F+G+G +V+ +Y+ +YY +++
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 201 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 260
A +Y FSS T LPW CNN WNT C L+ S G+ N
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHS----GAGTVTPFENF--------- 184
Query: 261 RTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTA 320
TSP E+W VL ++ I + G +R L CL ++W++ + C+ +GVKS+GKVVYFTA
Sbjct: 185 -TSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTA 243
Query: 321 TFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 380
TFPY++L IL +RGVTL GA+ GI+YYL P ++ + +VW DA +QIF+S G L
Sbjct: 244 TFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLT 303
Query: 381 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 440
+ SYNK+HNNCY+D + + N ATS AGFV+FSILGFM+ GV +S VA+ GPGLA
Sbjct: 304 ALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLA 363
Query: 441 FVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ-KKTY 499
F+A+P+A+T++P+S LWS LFF MLI LGL +QF +E LVTA +D + ++
Sbjct: 364 FIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRREL 423
Query: 500 VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQ 558
+ L +AV +L+G+ L ++ G+Y L D YA+S L+ +S V I ++YG ++
Sbjct: 424 LILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYD 483
Query: 559 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMA 617
+I+ M+G+ P +I W F++P + +F++ +Y P+ YN+ Y YP W +IG+ +A
Sbjct: 484 NIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLA 543
Query: 618 LSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 650
LSS++C+PL+ + L +T G +RL+ P
Sbjct: 544 LSSMVCVPLFVVITLLKTRG-PFRKRLRQLITP 575
>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
sapiens]
Length = 625
Score = 498 bits (1281), Expect = e-140
Identities = 246/566 (43%), Positives = 355/566 (62%), Gaps = 23/566 (4%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
R W Q++F+++ VG+AVGLGNVWRFPYLCY+NGGG F+ PY ++ + GIP+FF+E+S
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
GQF G + VW I P+FKG+GY MV+ Y YY +V+ FYY S T LPWA
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 220 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDD 279
C + WNT DC + + N S +NL+ + R SP E+W VL+LS
Sbjct: 172 CGHTWNTPDCVEIFRHEDCANASL-----ANLT--CDQLADRRSPVIEFWENKVLRLSGG 224
Query: 280 IGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEG 339
+ G + + CL W++V+ C+ +GVKS+GK+VYFTATFPYVVL +L VRGV L G
Sbjct: 225 LEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPG 284
Query: 340 AFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVII 399
A DGI+YYL P W K+ +VW DA +QIF+S G L + SYN+F+NNCY
Sbjct: 285 ALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYN----- 339
Query: 400 SITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSL 459
TS +AGFV+FSILGFMA GV +S+VA+ GPGLAF+AYP A+TL+P++PLW+
Sbjct: 340 -----GTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAA 394
Query: 460 LFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVA-GFLLGIPLTSQ 518
LFFFML+LLGL +QF +E +T ++D + + + + +++ + A F++ + + +
Sbjct: 395 LFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTD 454
Query: 519 AGIYWLLLMDNYAASFSLVVISCIM-CVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWR 577
G+Y L D Y+AS + ++ CV + ++YG + DI M+G+ P + + CW
Sbjct: 455 GGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWS 514
Query: 578 FVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTD 636
F +P + I +F V+ Y+P+ YN+ Y YP W A+G+ ALSS+LC+PL+ + L R
Sbjct: 515 FFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAK 574
Query: 637 GDTLLQRLKNATKPSRDWGPALLEHR 662
G T+ +R ++ T+P WG LE+R
Sbjct: 575 G-TMAERWQHLTQPI--WGLHHLEYR 597
>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
Length = 630
Score = 487 bits (1254), Expect = e-137
Identities = 237/572 (41%), Positives = 359/572 (62%), Gaps = 26/572 (4%)
Query: 86 AVPSEATKRDQNLKRGN---WGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPY 142
++P+ T L +G WG +++F+L+ +GYAV LGNVWRFPY+CY+NGGGAF+ PY
Sbjct: 62 SIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPY 121
Query: 143 FIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVIC 201
IM IF GIPLF+MEL+ GQ+ GC+ +WR I P+FKG+GY + +++ YI YYN ++
Sbjct: 122 TIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMA 181
Query: 202 IAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQR 261
A YY SS T LPW C N WNT +C N+T +L
Sbjct: 182 WALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNIT-----------------WTLHS 224
Query: 262 TSPSEEYWRLYVLKL--SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFT 319
TSP+EE++ +VL++ S + + G + L C+ + + V++ + +GVK+SGKVV+ T
Sbjct: 225 TSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVT 284
Query: 320 ATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGL 379
ATFPY++L++L VRG TL GA+ G+++YL P W K+LE VW DAA+QIF+SLG +G L
Sbjct: 285 ATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVL 344
Query: 380 ITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVA-DHGPG 438
+ ASYNKF+NNCY+D+++ S+ NC TS +GFVIF++LG+MA DVS VA D GP
Sbjct: 345 LAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPS 404
Query: 439 LAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKT 498
L F+ Y EA+ +P S ++++FF MLI LGL + F LE ++TA++DE + W +++
Sbjct: 405 LLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRER 464
Query: 499 YVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQ 558
+V L V + F + + G Y + L++ YA +++ ++ I VA+ + YG + +
Sbjct: 465 FV-LAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCR 523
Query: 559 DIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMAL 618
D++ MLGF P F++ICW +SP + FI+ ++ + Y YP W++ +G+ +
Sbjct: 524 DVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGT 583
Query: 619 SSVLCIPLYAMFRLCRTDGDTLLQRLKNATKP 650
SS +CIP Y +RL T G T +R+ + P
Sbjct: 584 SSFICIPTYIAYRLIITPG-TFKERIIKSITP 614
>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
Length = 617
Score = 479 bits (1234), Expect = e-135
Identities = 244/578 (42%), Positives = 364/578 (62%), Gaps = 17/578 (2%)
Query: 79 LAMAQNGAVPSEATKRDQNLK-RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGA 137
L + + V RD + + R WG +I+F+L+ VG+AV L NVWRFPYLCY+NGGGA
Sbjct: 34 LVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGA 93
Query: 138 FMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYN 197
F+ PY + LI G+PLF+MEL+ GQ+ +G VW+I P FKGVGY +++++ Y+G YYN
Sbjct: 94 FLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYN 153
Query: 198 VVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNH 257
V+I + YY FSS T LPW C + WN+ +C L NGS L + +
Sbjct: 154 VIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTD----PKLLNGSV-------LGNHTKY 202
Query: 258 SLQRTSPSEEYWRLYVLKLSDDIG--NFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKV 315
S + +P+ E++ VL L + G + G + LL CL V +V++ L +GVK+SGKV
Sbjct: 203 SKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKV 262
Query: 316 VYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCA 375
V+ TAT PY VL +L V GVTL GA +GI YL + ++ EA VW DAA+QIF+SLG
Sbjct: 263 VWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAG 322
Query: 376 WGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADH 435
+G LI ASYNKF NNCYRD+++ S NC TS +GF IFSILG+MA+ V++ VA
Sbjct: 323 FGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATE 382
Query: 436 GPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQ 495
G GL F+ YPEA++ L S W+++FF ML+ LGL + +E ++T + D+ + + +
Sbjct: 383 GAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDF--QVLKR 440
Query: 496 KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRN 555
+ T GV + FLL + ++ GIY L L+D +AA S++ + + + + YG
Sbjct: 441 HRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDR 500
Query: 556 YFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFL 615
+ DIQ M+GF P L++++CW+FVSPA + F++V ++I ++P+TY+ Y +P WA +G+
Sbjct: 501 FSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWG 560
Query: 616 MALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 653
+ALSS++ +P+Y +++ T G +L +RL P +
Sbjct: 561 IALSSMVLVPIYVIYKFLSTQG-SLWERLAYGITPENE 597
>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
dopamine), member 3 [Homo sapiens]
Length = 620
Score = 477 bits (1227), Expect = e-134
Identities = 234/558 (41%), Positives = 357/558 (63%), Gaps = 21/558 (3%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
R WG +I+F+L+ +G+AV L NVWRFPYLCY+NGGGAF+ PY + ++ G+PLF+MEL+
Sbjct: 60 RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119
Query: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
GQF +G GVW+I P+ KGVG+ ++++S Y+G +YNV+I A +Y FSS T LPW +
Sbjct: 120 LGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIH 179
Query: 220 CNNPWNTHDCAGVL--DASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKL- 276
CNN WN+ +C+ D+S ++G LN + T+P+ EY+ VL L
Sbjct: 180 CNNSWNSPNCSDAHPGDSSGDSSG-------------LNDTFG-TTPAAEYFERGVLHLH 225
Query: 277 -SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGV 335
S I + G R L CL + ++++ L +GVK+SGKVV+ TAT PYVVLT L +RGV
Sbjct: 226 QSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGV 285
Query: 336 TLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRD 395
TL GA DGI YL+ + ++ EA VW DAA+Q+ +SLG +G LI +SYNKF NNCYRD
Sbjct: 286 TLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRD 345
Query: 396 SVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISP 455
+++ + N TS +GFV+FS LG+MA V + VA GPGL F+ YPEA+ LP+S
Sbjct: 346 AIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSS 405
Query: 456 LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPL 515
W+++FF ML+ LG+ + +E+++T ++DE + + + + TL + +A FLL +
Sbjct: 406 AWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF--QLLHRHRELFTLFIVLATFLLSLFC 463
Query: 516 TSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQIC 575
+ GIY L+D++AA S++ I + + + YG + DIQ M G P L++++C
Sbjct: 464 VTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLC 523
Query: 576 WRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRT 635
W+ VSP + F++V +++ ++P Y Y +P WA A+G+++A SS+ +P+YA ++ C
Sbjct: 524 WKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSL 583
Query: 636 DGDTLLQRLKNATKPSRD 653
G + ++L A P +D
Sbjct: 584 PG-SFREKLAYAIAPEKD 600
>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 469 bits (1206), Expect = e-132
Identities = 235/550 (42%), Positives = 348/550 (63%), Gaps = 20/550 (3%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W ++I+FVL+ G VGLGNVWRFPYLCY+NGGGAF+ PYFI L G+P+FF+E+
Sbjct: 40 QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
Query: 159 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
GQ+ S+G + W +I P+F G+GY +V+ + + +YY V++ A YY F S LPW
Sbjct: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
Query: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLS 277
A+CN+ WNT C ++ + N S + S TSP E+W VL LS
Sbjct: 160 AHCNHSWNTPHC---MEDTMRKNKSVWITISST---------NFTSPVIEFWERNVLSLS 207
Query: 278 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 337
I + G ++ L CL + WLV F C+ +GV+S+GKVVYFTATFP+ +L +L VRG+TL
Sbjct: 208 PGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTL 267
Query: 338 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 397
GA GI +YL P ++ + +VW DA +QIF+S G + ++ SYNK+ N YRD +
Sbjct: 268 PGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCM 327
Query: 398 IISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 457
++ N TS +GF IFSILGFMA GVD++ VA+ GPGLAF+AYP+A+T++P+ W
Sbjct: 328 LLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFW 387
Query: 458 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK---KTYVTLGVAVAGFLLGIP 514
S+LFF ML+LLGL +QF +E +T++VD + L+K + V +LLG+
Sbjct: 388 SILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS--FLRKGYRREIFIAFVCSISYLLGLT 445
Query: 515 LTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQ 573
+ ++ G+Y L D YAAS L+ ++ C I +IYG N + I+ M+G+ P + +
Sbjct: 446 MVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMK 505
Query: 574 ICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRL 632
W ++P + +F++++Y P+TYN Y YP WA+ +G+ +ALSS+LC+PL + RL
Sbjct: 506 YSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRL 565
Query: 633 CRTDGDTLLQ 642
C+T+G L++
Sbjct: 566 CQTEGPFLVR 575
>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 469 bits (1206), Expect = e-132
Identities = 235/550 (42%), Positives = 348/550 (63%), Gaps = 20/550 (3%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W ++I+FVL+ G VGLGNVWRFPYLCY+NGGGAF+ PYFI L G+P+FF+E+
Sbjct: 40 QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
Query: 159 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
GQ+ S+G + W +I P+F G+GY +V+ + + +YY V++ A YY F S LPW
Sbjct: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
Query: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLS 277
A+CN+ WNT C ++ + N S + S TSP E+W VL LS
Sbjct: 160 AHCNHSWNTPHC---MEDTMRKNKSVWITISST---------NFTSPVIEFWERNVLSLS 207
Query: 278 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 337
I + G ++ L CL + WLV F C+ +GV+S+GKVVYFTATFP+ +L +L VRG+TL
Sbjct: 208 PGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTL 267
Query: 338 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 397
GA GI +YL P ++ + +VW DA +QIF+S G + ++ SYNK+ N YRD +
Sbjct: 268 PGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCM 327
Query: 398 IISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 457
++ N TS +GF IFSILGFMA GVD++ VA+ GPGLAF+AYP+A+T++P+ W
Sbjct: 328 LLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFW 387
Query: 458 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK---KTYVTLGVAVAGFLLGIP 514
S+LFF ML+LLGL +QF +E +T++VD + L+K + V +LLG+
Sbjct: 388 SILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS--FLRKGYRREIFIAFVCSISYLLGLT 445
Query: 515 LTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQ 573
+ ++ G+Y L D YAAS L+ ++ C I +IYG N + I+ M+G+ P + +
Sbjct: 446 MVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMK 505
Query: 574 ICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRL 632
W ++P + +F++++Y P+TYN Y YP WA+ +G+ +ALSS+LC+PL + RL
Sbjct: 506 YSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRL 565
Query: 633 CRTDGDTLLQ 642
C+T+G L++
Sbjct: 566 CQTEGPFLVR 575
>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
sapiens]
Length = 520
Score = 423 bits (1087), Expect = e-118
Identities = 211/499 (42%), Positives = 312/499 (62%), Gaps = 13/499 (2%)
Query: 167 GCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNT 226
G + VW I P+FKG+GY MV+ Y YY +V+ FYY S T LPWA C + WNT
Sbjct: 4 GSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNT 63
Query: 227 HDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEV 286
DC + + N S +NL+ + R SP E+W VL+LS + G +
Sbjct: 64 PDCVEIFRHEDCANASL-----ANLT--CDQLADRRSPVIEFWENKVLRLSGGLEVPGAL 116
Query: 287 RLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMY 346
+ CL W++V+ C+ +GVKS+GK+VYFTATFPYVVL +L VRGV L GA DGI+Y
Sbjct: 117 NWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIY 176
Query: 347 YLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCAT 406
YL P W K+ +VW DA +QIF+S G L + SYN+F+NNCY+D++I+++ N T
Sbjct: 177 YLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGT 236
Query: 407 SVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLI 466
S +AGFV+FSILGFMA GV +S+VA+ GPGLAF+AYP A+TL+P++PLW+ LFFFML+
Sbjct: 237 SFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLL 296
Query: 467 LLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVA-GFLLGIPLTSQAGIYWLL 525
LLGL +QF +E +T ++D + + + + +++ + A F++ + + + G+Y
Sbjct: 297 LLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQ 356
Query: 526 LMDNYAASFSLVVISCIM-CVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAII 584
L D Y+AS + ++ CV + ++YG + DI M+G+ P + + CW F +P +
Sbjct: 357 LFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVC 416
Query: 585 FFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQR 643
I +F V+ Y+P+ YN+ Y YP W A+G+ ALSS+LC+PL+ + L R G T+ +R
Sbjct: 417 MGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKG-TMAER 475
Query: 644 LKNATKPSRDWGPALLEHR 662
++ T+P WG LE+R
Sbjct: 476 WQHLTQPI--WGLHHLEYR 492
>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
Length = 634
Score = 392 bits (1006), Expect = e-109
Identities = 220/623 (35%), Positives = 333/623 (53%), Gaps = 103/623 (16%)
Query: 90 EATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFC 149
E ++++ R W N+ +++LT +G+ VGLGNVWRFPYLC +GGGAFM P+ I+L+
Sbjct: 22 ETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLE 81
Query: 150 GIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFF 208
GIPL ++E + GQ +G LGVW I P KG+G M+ S +G+YYN +I +Y F
Sbjct: 82 GIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLF 141
Query: 209 SSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEY 268
+S LPW+ C P N + V + + R+SP + +
Sbjct: 142 NSFQEPLPWSDC--PLNENQTGYVDECA------------------------RSSPVDYF 175
Query: 269 WRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLT 328
W L +S I + G ++ +L CL +W V+++C IRG++++GK VY T+T PYVVLT
Sbjct: 176 WYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLT 235
Query: 329 ILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKF 388
I +RG+TL+GA +GI++ TP ++ + W DA +Q+F+S A+GGLI+ +SYN
Sbjct: 236 IFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSV 295
Query: 389 HNNCYRDSVIISITNCATSVYAGFVIFSILG----------FMANHL----GVDVSR--- 431
HNNC +DSVI+SI N TSVY V++S++G F N L G D+
Sbjct: 296 HNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNV 355
Query: 432 -----------------------------------VADHGPGLAFVAYPEALTLLPISPL 456
A G GLAF+ + EA+T +P+SPL
Sbjct: 356 TQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPL 415
Query: 457 WSLLFFFMLILLGLGTQFCLLETLVTAIVD--EVGNEWILQKKTYVTLGVAVAGFLLGIP 514
WS+LFF ML LGL + F +E +V + D + +W K +T + + FL+G
Sbjct: 416 WSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKW---PKEVLTGLICLGTFLIGFI 472
Query: 515 LTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQI 574
T +G YWL L+D+YA S L++I+ +++Y+YG + +DI+ M+G P +F+Q+
Sbjct: 473 FTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQV 532
Query: 575 CWRFVSP--AIIFFILVFTVIQYQPITYNHY-------------QYPGWAVAIGFLMALS 619
WR VSP +I F+ F V Q +TY+ + YP W + ++A
Sbjct: 533 TWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGV 592
Query: 620 SVLCIPLYAMFRL----CRTDGD 638
L IP YA+++L C+ GD
Sbjct: 593 PSLTIPGYAIYKLIRNHCQKPGD 615
>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
Length = 628
Score = 365 bits (936), Expect = e-100
Identities = 210/602 (34%), Positives = 321/602 (53%), Gaps = 96/602 (15%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W N+ +++L+ G+AVGLGN+WRFPYLC GGGAF+ PY I L+F GIP+F +EL
Sbjct: 17 ERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVEL 76
Query: 159 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
+ GQ +G +GVW ISP GVG G + +S I +YYN ++ +Y +S H LPW
Sbjct: 77 AIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPW 136
Query: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLS 277
+ C N G ++ Q +S +W L ++
Sbjct: 137 SSCPPDLNR---TGFVE-----------------------ECQGSSAVSYFWYRQTLNIT 170
Query: 278 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 337
DI + G ++ LL CL SW VV++C+IRG++++GKV+YFTA FPY+VLTI +RG+TL
Sbjct: 171 ADINDSGSIQWWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTL 230
Query: 338 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 397
GA G++Y TP + +VW DAA+QIF+SL A+GG I ASYN N+C +D+V
Sbjct: 231 PGATKGLIYLFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAV 290
Query: 398 IISITNCATSVYAGFVIFSILGFMA----------NHLGV-------DVSRVADHGPGLA 440
+I++ N TS+YA +FS+LGF A N L + + S D P +
Sbjct: 291 VIALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVL 350
Query: 441 F---VAYPEALTLLPI--------------------------------SPLWSLLFFFML 465
+P+ + LP+ +P+W++LFF ML
Sbjct: 351 MHLNATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGML 410
Query: 466 ILLGLGTQFCLLETLVTAIVD-EVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWL 524
LGL T F +E ++T ++D V W+ K +T V + FL T Q+G YWL
Sbjct: 411 FTLGLSTMFGTVEAVITPLLDVGVLPRWV--PKEALTGLVCLVCFLSATCFTLQSGNYWL 468
Query: 525 LLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAII 584
+ DN+AAS +L++++ + V ++Y+YG + + DI M G P ++++ WR VSP ++
Sbjct: 469 EIFDNFAASPNLLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLL 528
Query: 585 -FFILVFTVIQYQPITYNHYQ-------------YPGWAVAIGFLMALSSVLCIPLYAMF 630
F+ ++ ++P+ Y + YPGWA A L++L VL +P+ A+
Sbjct: 529 TIFVAYIILLFWKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALA 588
Query: 631 RL 632
+L
Sbjct: 589 QL 590
>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
sapiens]
Length = 592
Score = 364 bits (935), Expect = e-100
Identities = 213/610 (34%), Positives = 317/610 (51%), Gaps = 102/610 (16%)
Query: 103 WGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQ 162
W N ++FV + YAVGLGNVWRFPYLC GGG+F+ PY IMLI G+PL ++EL+ GQ
Sbjct: 8 WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67
Query: 163 FASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCN 221
QG +G WR ISP GVG +VVS ++ +YYNV+ AF+Y F S LPW+ C
Sbjct: 68 RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVC- 126
Query: 222 NPWNTHDCAGVLDASNLTNGSRPAALPSNLSHL-LNHSLQRTSPSEEYWRLYVLKLSDDI 280
P N +H + ++ S ++ +W L +S +
Sbjct: 127 --------------------------PLNGNHTGYDEECEKASSTQYFWYRKTLNISPSL 160
Query: 281 GNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGA 340
G V+ CL ++WLVV+LC++RG +S+GKVVYFTA+ PY VL I +RG+TL GA
Sbjct: 161 QENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGA 220
Query: 341 FDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIIS 400
+G+MY TP+ +++ K W +AA+QIF+SLG +G LI ASYN+ NNC + ++I+S
Sbjct: 221 TNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVS 280
Query: 401 ITNCATSVYAGFVIFS---------------------------------------ILGFM 421
+ N TS++A V FS + G++
Sbjct: 281 LINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYL 340
Query: 422 ANHLGVDVSRV---------------ADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLI 466
A+ S + A G GLAF+ Y EA+ + +S LWS+L+FFML+
Sbjct: 341 ASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLL 400
Query: 467 LLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLL 526
+LG+G+ ++T + D L K+ L V + +G+ T +AG YW +
Sbjct: 401 MLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGL-VCLVNCAIGMVFTMEAGNYWFDI 459
Query: 527 MDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFF 586
++YAA+ SL++I + +A+ Y+YG R + D++ M G ++++ W VSP +I
Sbjct: 460 FNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVS 519
Query: 587 ILVFTVIQYQPITYNHYQ-------------YPGWAVAIGFLMALSSVLCIPLYAM---- 629
+ VF + Y YQ YP +A+A+ L+ SS +CIPL A+
Sbjct: 520 LFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFV 579
Query: 630 -FRLCRTDGD 638
RL R D D
Sbjct: 580 QRRLKRGDAD 589
>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
sapiens]
Length = 555
Score = 302 bits (774), Expect = 6e-82
Identities = 191/610 (31%), Positives = 290/610 (47%), Gaps = 139/610 (22%)
Query: 103 WGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQ 162
W N ++FV + YAVGLGNVWRFPYLC GGG+F+ PY IMLI G+PL ++EL+ GQ
Sbjct: 8 WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67
Query: 163 FASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCN 221
QG +G WR ISP GVG +VVS ++ +YYNV+ AF+Y F S LPW+ C
Sbjct: 68 RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVC- 126
Query: 222 NPWNTHDCAGVLDASNLTNGSRPAALPSNLSHL-LNHSLQRTSPSEEYWRLYVLKLSDDI 280
P N +H + ++ S ++ +W L +S +
Sbjct: 127 --------------------------PLNGNHTGYDEECEKASSTQYFWYRKTLNISPSL 160
Query: 281 GNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGA 340
G V+ CL ++WLVV+LC++RG +S+GK+
Sbjct: 161 QENGGVQWEPALCLLLAWLVVYLCILRGTESTGKI------------------------- 195
Query: 341 FDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIIS 400
+++ K W +AA+QIF+SLG +G LI ASYN+ NNC + ++I+S
Sbjct: 196 ------------EQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVS 243
Query: 401 ITNCATSVYAGFVIFS---------------------------------------ILGFM 421
+ N TS++A V FS + G++
Sbjct: 244 LINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYL 303
Query: 422 ANHLGVDVSRV---------------ADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLI 466
A+ S + A G GLAF+ Y EA+ + +S LWS+L+FFML+
Sbjct: 304 ASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLL 363
Query: 467 LLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLL 526
+LG+G+ ++T + D L K+ L V + +G+ T +AG YW +
Sbjct: 364 MLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGL-VCLVNCAIGMVFTMEAGNYWFDI 422
Query: 527 MDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFF 586
++YAA+ SL++I + +A+ Y+YG R + D++ M G ++++ W VSP +I
Sbjct: 423 FNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVS 482
Query: 587 ILVFTVIQYQPITYNHYQ-------------YPGWAVAIGFLMALSSVLCIPLYAM---- 629
+ VF + Y YQ YP +A+A+ L+ SS +CIPL A+
Sbjct: 483 LFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFV 542
Query: 630 -FRLCRTDGD 638
RL R D D
Sbjct: 543 QRRLKRGDAD 552
>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
Length = 727
Score = 298 bits (764), Expect = 9e-81
Identities = 183/607 (30%), Positives = 303/607 (49%), Gaps = 102/607 (16%)
Query: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
R W ++++++L +G++VGLGN+WRFPYLC +NGGGA++ PY ++LI GIPLFF+EL+
Sbjct: 60 RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELA 119
Query: 160 FGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWA 218
GQ +G +GVW I P G+G+ +V ++G+YYNV+I + +YFF S + LPW+
Sbjct: 120 VGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWS 179
Query: 219 YCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSD 278
C P + V++A +++S + +W L +SD
Sbjct: 180 EC--PVVRNGSVAVVEAE----------------------CEKSSATTYFWYREALDISD 215
Query: 279 DIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLE 338
I G + + CL V+W +V + +++G++SSGKV+YF++ FPYVVL VRG+ L
Sbjct: 216 SISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLR 275
Query: 339 GAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVI 398
GA DGI++ TP+ DK+L+ +VW +AA+Q+F++LG +GG+I +SYNK NNC+ D+ +
Sbjct: 276 GAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAAL 335
Query: 399 ISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALT--LLP---- 452
+S N TSV A V+F++LGF AN + + V ++ + L+ L+P
Sbjct: 336 VSFINFFTSVLATLVVFAVLGFKANIM--NEKCVVENAEKILGYLNTNVLSRDLIPPHVN 393
Query: 453 ISPLWSLLFFFMLILL---------GLGTQFCLLETLVTAIVDEVGNEWILQKKTY---- 499
S L + + M ++ LG CLLE + V G +I +
Sbjct: 394 FSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFP 453
Query: 500 ------VTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIM---CVAIMYI 550
V + + LG + + AGI ++D + + + C + V ++++
Sbjct: 454 ASPFWSVMFFLMLINLGLGSMIGTMAGI-TTPIIDTFKVPKEMFTVGCCVFAFLVGLLFV 512
Query: 551 YGHRNYF----------------------------------QDIQMMLGFPPPLFFQICW 576
NYF Q++ MLGF P F+ W
Sbjct: 513 QRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMW 572
Query: 577 RFVSPAIIFFILVFTVIQY------------QPITYNHYQYPGWAVAIGFLMALSSVLCI 624
+FVSP + + ++IQ + + +P WA+A+ + + + L I
Sbjct: 573 KFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPI 632
Query: 625 PLYAMFR 631
P+ + R
Sbjct: 633 PVVFVLR 639
>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
sapiens]
Length = 730
Score = 279 bits (713), Expect = 7e-75
Identities = 135/327 (41%), Positives = 200/327 (61%), Gaps = 27/327 (8%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W ++++++L VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+ GIPLFF+EL
Sbjct: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
Query: 159 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
S GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF S LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
Query: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 276
C L N SH + +++S + YW L +
Sbjct: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214
Query: 277 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVT 336
S I G + + CL +W++V L +I+G++SSGK++YF++ FPYVVL +R
Sbjct: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFL 274
Query: 337 LEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDS 396
L G+ DGI + TP+ + +LE KVW +AA+Q+F++LG +GG+I +SYNK NNC+ D+
Sbjct: 275 LNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDA 334
Query: 397 VIISITNCATSVYAGFVIFSILGFMAN 423
V++S N TSV A V+F++LGF AN
Sbjct: 335 VLVSFINFFTSVLATLVVFAVLGFKAN 361
Score = 127 bits (319), Expect = 4e-29
Identities = 63/211 (29%), Positives = 119/211 (56%), Gaps = 17/211 (8%)
Query: 433 ADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEW 492
A G GLAF+A+ EA+T P SP WS++FF ML+ LGLG+ F +E +VT IVD
Sbjct: 435 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDT----- 489
Query: 493 ILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYG 552
+K +T+ + F +G+ ++G Y++ + D+Y+A+ L+++ + +A+ ++YG
Sbjct: 490 FKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYG 549
Query: 553 HRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQ--YQPITYNHY------- 603
+ +D++ MLGF P ++ W+++SP ++ +L+ +V+ P YN +
Sbjct: 550 IDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASE 609
Query: 604 ---QYPGWAVAIGFLMALSSVLCIPLYAMFR 631
YP W + + + + ++L +P+ + R
Sbjct: 610 EFLSYPTWGLVVCVSLVVFAILPVPVVFIVR 640
>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
Length = 736
Score = 223 bits (569), Expect = 4e-58
Identities = 159/622 (25%), Positives = 277/622 (44%), Gaps = 107/622 (17%)
Query: 89 SEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIF 148
+E + + L R W ++ E++L VG+++ +WRF YL +GG +F Y ML
Sbjct: 92 TEKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFL 151
Query: 149 CGIPLFFMELSFGQFASQGCLGVWRI-SPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYF 207
G+PL F+E++ GQ QG +GVW+I +P GVGY +V +G+Y+NVV +Y
Sbjct: 152 VGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYM 211
Query: 208 FSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEE 267
S +PW C N+ +G P +RT+PS
Sbjct: 212 SQSFQFPVPWEKCPLTMNS-------------SGFDPEC-------------ERTTPSIY 245
Query: 268 YWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVL 327
+W LK SD I + G L+ + W +V +I G+KS+GKV+Y P ++
Sbjct: 246 FWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFII 305
Query: 328 TILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGG--------- 378
F+R + LEGA G+ + + + VW A Q+ + G G
Sbjct: 306 VGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMP 365
Query: 379 ----------------LITMASYNKF-------------HNNCYRDS-VIISITNCA--- 405
L+T+ + F H C R++ +++ + N
Sbjct: 366 QSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLINLGKLP 425
Query: 406 -------------TSVYAGFV------IFSILGFMANHLGVDVSRV-ADHGPGLAFVAYP 445
TS+Y ++ I S++ ++ + A GP AF+++
Sbjct: 426 PDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFV 485
Query: 446 EALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTL-GV 504
EA++ LP S WS +FF ML+ +GL + +++ ++T + D +K T + + GV
Sbjct: 486 EAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFS---FFRKHTKLLIVGV 542
Query: 505 AVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMML 564
+ F+ G+ T +G Y++ L+ +Y F ++V+ +A+ + YG R + D+ ++L
Sbjct: 543 FLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILL 602
Query: 565 GFPPPLFFQICWRFVSPAIIFFILVFTVIQ--YQPITYNHYQ----------YPGWAVAI 612
G P F W + P ++ I V ++ +PITY + YP WA+ +
Sbjct: 603 GHPISPIFGWLWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVLRPYPPWALLL 662
Query: 613 GFLMALSSVLCIPLYAMFRLCR 634
++ L +++ +P+ A F CR
Sbjct: 663 --MITLFAIVILPIPAYFVYCR 682
>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
sapiens]
Length = 623
Score = 210 bits (534), Expect = 4e-54
Identities = 108/276 (39%), Positives = 159/276 (57%), Gaps = 27/276 (9%)
Query: 150 GIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFF 208
GIPLFF+ELS GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF
Sbjct: 4 GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63
Query: 209 SSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEE 267
S LPW C L N SH + +++S +
Sbjct: 64 QSFQQPLPWDQC-------------------------PLVKNASHTFVEPECEQSSATTY 98
Query: 268 YWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVL 327
YW L +S I G + + CL +W++V L +I+G++SSGK++YF++ FPYVVL
Sbjct: 99 YWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVL 158
Query: 328 TILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNK 387
+R L G+ DGI + TP+ + +LE KVW +AA+Q+F++LG +GG+I +SYNK
Sbjct: 159 ICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNK 218
Query: 388 FHNNCYRDSVIISITNCATSVYAGFVIFSILGFMAN 423
NNC+ D+V++S N TSV A V+F++LGF AN
Sbjct: 219 RDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKAN 254
Score = 127 bits (319), Expect = 4e-29
Identities = 63/211 (29%), Positives = 119/211 (56%), Gaps = 17/211 (8%)
Query: 433 ADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEW 492
A G GLAF+A+ EA+T P SP WS++FF ML+ LGLG+ F +E +VT IVD
Sbjct: 328 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDT----- 382
Query: 493 ILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYG 552
+K +T+ + F +G+ ++G Y++ + D+Y+A+ L+++ + +A+ ++YG
Sbjct: 383 FKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYG 442
Query: 553 HRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQ--YQPITYNHY------- 603
+ +D++ MLGF P ++ W+++SP ++ +L+ +V+ P YN +
Sbjct: 443 IDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASE 502
Query: 604 ---QYPGWAVAIGFLMALSSVLCIPLYAMFR 631
YP W + + + + ++L +P+ + R
Sbjct: 503 EFLSYPTWGLVVCVSLVVFAILPVPVVFIVR 533
>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
sapiens]
Length = 289
Score = 169 bits (428), Expect = 8e-42
Identities = 87/233 (37%), Positives = 131/233 (56%), Gaps = 30/233 (12%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W ++++++L VG++VGLGNVWRFPYLC +NGGGA++ PY I+L+ GIPLFF+EL
Sbjct: 60 ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119
Query: 159 SFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
S GQ +G +GVW ISP G+G+ VV ++ +YYNV+I + +YF S LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179
Query: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH-LLNHSLQRTSPSEEYWRLYVLKL 276
C L N SH + +++S + YW L +
Sbjct: 180 DQC-------------------------PLVKNASHTFVEPECEQSSATTYYWYREALNI 214
Query: 277 SDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTI 329
S I G + + CL +W++V L +I+G++SSGKV + P+++L I
Sbjct: 215 SSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLI 264
>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform b [Homo sapiens]
Length = 200
Score = 159 bits (403), Expect = 6e-39
Identities = 67/132 (50%), Positives = 93/132 (70%), Gaps = 1/132 (0%)
Query: 99 KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158
+R W ++I+FVL+ G VGLGNVWRFPYLCY+NGGGAF+ PYFI L G+P+FF+E+
Sbjct: 40 QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
Query: 159 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217
GQ+ S+G + W +I P+F G+GY +V+ + + +YY V++ A YY F S LPW
Sbjct: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
Query: 218 AYCNNPWNTHDC 229
A+CN+ WNT C
Sbjct: 160 AHCNHSWNTPHC 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.458
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,390,816
Number of Sequences: 37866
Number of extensions: 1234272
Number of successful extensions: 4067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3911
Number of HSP's gapped (non-prelim): 58
length of query: 706
length of database: 18,247,518
effective HSP length: 109
effective length of query: 597
effective length of database: 14,120,124
effective search space: 8429714028
effective search space used: 8429714028
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.