Guide to the Human Genome
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Search of human proteins with 67078404

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform
a [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...   744   0.0  
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...   588   e-168
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           96   4e-20
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                 80   4e-15
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                  80   4e-15
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 79   9e-15
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...    77   2e-14
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...    63   5e-10
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       62   1e-09
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       62   1e-09
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        59   5e-09
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...    59   9e-09
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        58   2e-08
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        58   2e-08
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...    58   2e-08
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...    52   7e-07
gi|41872631 fatty acid synthase [Homo sapiens]                         52   1e-06
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    49   7e-06
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...    49   7e-06
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...    49   1e-05
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    47   4e-05
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]    41   0.002
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]      41   0.002
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     39   0.010
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     33   0.41 
gi|110347463 human immunodeficiency virus type I enhancer bindin...    31   1.6  
gi|197927207 crystallin, zeta isoform c [Homo sapiens]                 31   2.1  
gi|7705353 three prime repair exonuclease 1 isoform a [Homo sapi...    30   4.6  
gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo...    30   4.6  
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]      29   6.0  

>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score =  744 bits (1920), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL 60
           MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL
Sbjct: 1   MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL 60

Query: 61  KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT 120
           KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT
Sbjct: 61  KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT 120

Query: 121 GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ 180
           GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ
Sbjct: 121 GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ 180

Query: 181 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 240
           LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE
Sbjct: 181 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 240

Query: 241 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL 300
           ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL
Sbjct: 241 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL 300

Query: 301 IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS 360
           IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS
Sbjct: 301 IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS 360

Query: 361 MKPFISSKQILTM 373
           MKPFISSKQILTM
Sbjct: 361 MKPFISSKQILTM 373


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score =  588 bits (1516), Expect = e-168
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 77  MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLG 136
           MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLG
Sbjct: 1   MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLG 60

Query: 137 TWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGV 196
           TWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGV
Sbjct: 61  TWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGV 120

Query: 197 GQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQ 256
           GQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQ
Sbjct: 121 GQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQ 180

Query: 257 PRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWK 316
           PRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWK
Sbjct: 181 PRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWK 240

Query: 317 KDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM 373
           KDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM
Sbjct: 241 KDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM 297


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 23/274 (8%)

Query: 23  ASGCHGPAAS--SYSASAEPARVRALVYGHHGDPAKV-VELKNLELAAVRGSDVRVKMLA 79
           AS    PAAS  + +A+A P  +R LV    G   KV ++ +     A     + +++ A
Sbjct: 26  ASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRA 85

Query: 80  APINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWR 139
             +N +D+   QG Y  LP LP   G EG   V+AVG  V+  K GD V+  N   G W+
Sbjct: 86  CGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRS-GMWQ 144

Query: 140 TEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQA 199
            E          +P  +  + AA L VN  TAY +L DF  LQPG SV+ + +  GVG A
Sbjct: 145 EEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMA 204

Query: 200 VIQIAAALGLRTI-NVVRDRPDIQKLSDRLKSLGAEHVIT------EEELRRPEMKNFFK 252
            +Q+      RT+ NV           + LK  G  H I        +E+++   K    
Sbjct: 205 AVQLC-----RTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGV-- 257

Query: 253 DMPQPRLALNCVGGKSSTELLRQLARGGTMVTYG 286
                 + ++ +GG  + +    L   G +VTYG
Sbjct: 258 -----DIVMDPLGGSDTAKGYNLLKPMGKVVTYG 286


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 62/268 (23%), Positives = 119/268 (44%), Gaps = 15/268 (5%)

Query: 43  VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPA 102
           +RA+     G P  +    ++ +   +   V +K+ A  +NP +  +  G Y   P LP 
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 103 VGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAA 162
             G++    + AVG N +  K GD V  ++   G +   A+ ++  + ++P  +  +  A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 163 TLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQ 222
            +G+   TAYR L+    ++ G+SV+ + ++ GVG A  QIA A GL+ +       + Q
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA-GTEEGQ 186

Query: 223 KLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTM 282
           K+   +   GA  V    E+   +    +       + +  +   + ++ L  L+ GG +
Sbjct: 187 KI---VLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRV 243

Query: 283 VTYGG-----------MAKQPVVASVSL 299
           +  G            MAK+  +  V+L
Sbjct: 244 IVVGSRGTIEINPRDTMAKESSIIGVTL 271


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 62/268 (23%), Positives = 119/268 (44%), Gaps = 15/268 (5%)

Query: 43  VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPA 102
           +RA+     G P  +    ++ +   +   V +K+ A  +NP +  +  G Y   P LP 
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 103 VGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAA 162
             G++    + AVG N +  K GD V  ++   G +   A+ ++  + ++P  +  +  A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 163 TLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQ 222
            +G+   TAYR L+    ++ G+SV+ + ++ GVG A  QIA A GL+ +       + Q
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA-GTEEGQ 186

Query: 223 KLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTM 282
           K+   +   GA  V    E+   +    +       + +  +   + ++ L  L+ GG +
Sbjct: 187 KI---VLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRV 243

Query: 283 VTYGG-----------MAKQPVVASVSL 299
           +  G            MAK+  +  V+L
Sbjct: 244 IVVGSRGTIEINPRDTMAKESSIIGVTL 271


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 46/170 (27%), Positives = 85/170 (50%)

Query: 43  VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPA 102
           +RA+     G P  +    ++ +   +   V +K+ A  +NP +  +  G Y   P LP 
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 103 VGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAA 162
             G++    + AVG N +  K GD V  ++   G +   A+ ++  + ++P  +  +  A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 163 TLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTI 212
            +G+   TAYR L+    ++ G+SV+ + ++ GVG A  QIA A GL+ +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKIL 177


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 69/268 (25%), Positives = 120/268 (44%), Gaps = 12/268 (4%)

Query: 19  GLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKML 78
           G  PA G  G  +     + E   +RA+V    G   K+  L    +   +  ++++++ 
Sbjct: 21  GKEPAEGGGGDGSHRLGDAQE---MRAVVLAGFGGLNKL-RLFRKAMPEPQDGELKIRVK 76

Query: 79  AAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTW 138
           A  +N  D+ + QGN    P+ P V G E    V A+G +V G + GD V+ A      W
Sbjct: 77  ACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVM-AFVNYNAW 135

Query: 139 RTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQ 198
                   E + ++P D+    AA   +N  TAY ML +   L+ G SV+ +++  GVGQ
Sbjct: 136 AEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQ 195

Query: 199 AVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPR 258
           AV Q+ + +   T+         + + D +  L   +    +E++R   +          
Sbjct: 196 AVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGV-------D 248

Query: 259 LALNCVGGKSSTELLRQLARGGTMVTYG 286
           + L+C+ G ++ + L  L   GT + YG
Sbjct: 249 IVLDCLCGDNTGKGLSLLKPLGTYILYG 276


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 62/247 (25%), Positives = 99/247 (40%), Gaps = 56/247 (22%)

Query: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115
           K   ++ +E+A  +  +VR+KM+AA I  SD +++ GN   +  LP + G+E    V +V
Sbjct: 20  KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN--LVTPLPVILGHEAAGIVESV 77

Query: 116 GSNVTGLKPGDWVIPA-------------------------------------------- 131
           G  VT +KPGD VIP                                             
Sbjct: 78  GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137

Query: 132 ---NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188
                G+ T+    V  E A+ ++ +  PL+    +G    T Y   +   ++ PG S  
Sbjct: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG-STC 196

Query: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247
                 GVG +V+    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 197 AVFGLGGVGLSVVMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251

Query: 248 KNFFKDM 254
           +   K+M
Sbjct: 252 QEVLKEM 258


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 64/234 (27%), Positives = 103/234 (44%), Gaps = 7/234 (2%)

Query: 72  DVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIP 130
           +V +K+ A+ +N +D+   QG Y   P    + G E    V  +G    G  K GD  + 
Sbjct: 29  EVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMA 88

Query: 131 ANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQN 190
              G G  +   V  E  L+ +P  + L  AA +     TA+++L     +Q GD V+ +
Sbjct: 89  LLPGGGQAQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147

Query: 191 ASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNF 250
           A  SGVG A IQ+    G   +     +  +Q ++++L    A     +E+     +K  
Sbjct: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK-- 203

Query: 251 FKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 303
           F       L L+C+GG    + +  LA  G  V YG M    +   + S L+FK
Sbjct: 204 FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 64/234 (27%), Positives = 103/234 (44%), Gaps = 7/234 (2%)

Query: 72  DVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIP 130
           +V +K+ A+ +N +D+   QG Y   P    + G E    V  +G    G  K GD  + 
Sbjct: 29  EVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMA 88

Query: 131 ANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQN 190
              G G  +   V  E  L+ +P  + L  AA +     TA+++L     +Q GD V+ +
Sbjct: 89  LLPGGGQAQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147

Query: 191 ASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNF 250
           A  SGVG A IQ+    G   +     +  +Q ++++L    A     +E+     +K  
Sbjct: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK-- 203

Query: 251 FKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 303
           F       L L+C+GG    + +  LA  G  V YG M    +   + S L+FK
Sbjct: 204 FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 72/296 (24%), Positives = 132/296 (44%), Gaps = 34/296 (11%)

Query: 59  ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSN 118
           ELK  EL  ++  +V ++ L   ++P     ++     L E   + G + VA+VV    N
Sbjct: 23  ELKTAELPPLKNGEVLLEALFLTVDP----YMRVAAKRLKEGDTMMGQQ-VAKVVE-SKN 76

Query: 119 VTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLGVNPCTAYR 173
           V    P   ++ A+ G   W T ++      E+ L + P  IPL  A  T+G+   TAY 
Sbjct: 77  VA--LPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYF 131

Query: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGA 233
            L++   ++ G++V+ NA+   VG  V QIA   G + +  V     +      L+ LG 
Sbjct: 132 GLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA----YLQKLGF 187

Query: 234 EHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGTMV------ 283
           + V   + +   E +   K  P      +C    VGG+ S  ++ Q+ + G +       
Sbjct: 188 DVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243

Query: 284 TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQ 339
           TY      P      ++I+++L++  F + +W+ D      K+L+  + ++ R  +
Sbjct: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENE 299


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 59/247 (23%), Positives = 98/247 (39%), Gaps = 56/247 (22%)

Query: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115
           K   ++++E+A  +  +VR+KM+A  I  +D +++ GN   +  LP + G+E    V +V
Sbjct: 20  KPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGN--LVTPLPVILGHEAAGIVESV 77

Query: 116 GSNVTGLKPGDWVIPANA------------------------------------------ 133
           G  VT +KPGD VIP                                             
Sbjct: 78  GEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137

Query: 134 -----GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188
                G  T+    V  E A+ ++ +  PL+    +G    T Y   ++  ++ PG S  
Sbjct: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196

Query: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247
                 GVG + +    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 197 AVFGLGGVGLSAVMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251

Query: 248 KNFFKDM 254
           +   K+M
Sbjct: 252 QEVLKEM 258


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 71/285 (24%), Positives = 127/285 (44%), Gaps = 34/285 (11%)

Query: 59  ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSN 118
           ELK  EL  ++  +V ++ L   ++P     ++     L E   + G + VA+VV    N
Sbjct: 23  ELKTAELPPLKNGEVLLEALFLTVDP----YMRVAAKRLKEGDTMMGQQ-VAKVVE-SKN 76

Query: 119 VTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLGVNPCTAYR 173
           V    P   ++ A+ G   W T ++      E+ L + P  IPL  A  T+G+   TAY 
Sbjct: 77  VA--LPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYF 131

Query: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGA 233
            L++   ++ G++V+ NA+   VG  V QIA   G + +  V     +      L+ LG 
Sbjct: 132 GLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA----YLQKLGF 187

Query: 234 EHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGTMV------ 283
           + V   + +   E +   K  P      +C    VGG+ S  ++ Q+ + G +       
Sbjct: 188 DVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243

Query: 284 TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELI 328
           TY      P      ++I+++L++  F + +W+ D      K+L+
Sbjct: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLL 288


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 71/285 (24%), Positives = 127/285 (44%), Gaps = 34/285 (11%)

Query: 59  ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSN 118
           ELK  EL  ++  +V ++ L   ++P     ++     L E   + G + VA+VV    N
Sbjct: 23  ELKTAELPPLKNGEVLLEALFLTVDP----YMRVAAKRLKEGDTMMGQQ-VAKVVE-SKN 76

Query: 119 VTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLGVNPCTAYR 173
           V    P   ++ A+ G   W T ++      E+ L + P  IPL  A  T+G+   TAY 
Sbjct: 77  VA--LPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYF 131

Query: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGA 233
            L++   ++ G++V+ NA+   VG  V QIA   G + +  V     +      L+ LG 
Sbjct: 132 GLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA----YLQKLGF 187

Query: 234 EHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGTMV------ 283
           + V   + +   E +   K  P      +C    VGG+ S  ++ Q+ + G +       
Sbjct: 188 DVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243

Query: 284 TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELI 328
           TY      P      ++I+++L++  F + +W+ D      K+L+
Sbjct: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLL 288


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 56/247 (22%)

Query: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115
           K   ++ +E+A  +  +VR+KM+A  I  +D +++ G    +  LP + G+E    V +V
Sbjct: 20  KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT--MVTPLPVILGHEAAGIVESV 77

Query: 116 GSNVTGLKPGDWVIPAN------------------------------------------- 132
           G  VT +KPGD VIP                                             
Sbjct: 78  GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 137

Query: 133 ----AGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188
                G+ T+    V  E A+ ++ +  PL+    +G    T Y   ++  ++ PG S  
Sbjct: 138 IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196

Query: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247
                 GVG + I    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 197 AVFGLGGVGLSAIMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251

Query: 248 KNFFKDM 254
           +   K+M
Sbjct: 252 QEVLKEM 258


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 76/338 (22%), Positives = 125/338 (36%), Gaps = 70/338 (20%)

Query: 39  EPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLP 98
           E  + +A V    G P  + E+   E+A  +  +VR+K++A  +  +D   + G     P
Sbjct: 4   EVIKCKAAVAWEAGKPLSIEEI---EVAPPKAHEVRIKIIATAVCHTDAYTLSGAD---P 57

Query: 99  E--LPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPA------------------------- 131
           E   P + G+EG   V +VG  VT LK GD VIP                          
Sbjct: 58  EGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVT 117

Query: 132 ----------------------NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPC 169
                                   G  T+    V ++ ++ ++    PL     LG    
Sbjct: 118 QGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGIS 177

Query: 170 TAYRMLMDFEQLQPGDSVIQNASNSGVGQAVI---QIAAALGLRTINVVRDRPDIQKLSD 226
           T Y   ++  +L+PG SV       GVG AVI   ++A A  +  +++ +D+        
Sbjct: 178 TGYGAAVNTAKLEPG-SVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDK------FA 230

Query: 227 RLKSLGAEHVITEEELRRPEMKNFFKDMPQPRL--ALNCVGG-KSSTELLRQLARG-GTM 282
           R K  GA   I  ++  +P ++    +M    +  +  C+G  K     L    +G G  
Sbjct: 231 RAKEFGATECINPQDFSKP-IQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVS 289

Query: 283 VTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHS 320
           V  G  A    +A+    +      +G     WK   S
Sbjct: 290 VVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVES 327


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 10/102 (9%)

Query: 114  AVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR 173
            A G  V GL P         GL T     + S + L  VPS+  L+ AA++ V   TAY 
Sbjct: 1608 ASGKRVMGLVPAK-------GLAT---SVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYY 1657

Query: 174  MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVV 215
             L+   +++PG++++ ++ + GVGQA I IA +LG R    V
Sbjct: 1658 ALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTV 1699


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 64/254 (25%), Positives = 102/254 (40%), Gaps = 19/254 (7%)

Query: 72  DVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPA 131
           D+ V+     +N SDIN   G Y    + P   G EG+ +VVA+G + +        + A
Sbjct: 64  DLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAV-A 122

Query: 132 NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNA 191
               G++    V        VPS  P     TL V+  TAY  L +   L  G  V+  A
Sbjct: 123 YMAPGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTA 180

Query: 192 SNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFF 251
           +  G GQ  +Q++       I          + S  LKSLG +  I  +    P      
Sbjct: 181 AAGGTGQFAMQLSKKAKCHVIGTCSS----DEKSAFLKSLGCDRPINYK--TEPVGTVLK 234

Query: 252 KDMPQ-PRLALNCVGGKSSTELLRQLARGGTMVTYGGMA-------KQPVVASV--SLLI 301
           ++ P+   +    VGG      +  LA  G ++  G ++         PV A    + L+
Sbjct: 235 QEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLL 294

Query: 302 FKDLKLRGFWLSQW 315
            K   ++GF+L+ +
Sbjct: 295 KKSASVQGFFLNHY 308


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 74/335 (22%), Positives = 123/335 (36%), Gaps = 72/335 (21%)

Query: 53  DPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQV 112
           +  K + ++ +E+A  +  +VR++++A  +  +D  +I   +  L   P + G+E    V
Sbjct: 17  EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA-FPVIVGHEAAGIV 75

Query: 113 VAVGSNVTGLKPGDWVIPANA--------------------------------------- 133
            ++G  VT +KPGD VIP  A                                       
Sbjct: 76  ESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSR 135

Query: 134 ------------GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQL 181
                       G  T+    V S+  L ++  D  L+    LG    T Y   ++  ++
Sbjct: 136 FTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKV 195

Query: 182 QPGDSVIQNASNSGVG-QAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 240
            PG S        GVG  AV+   AA   R I +  +     K     K+LGA   +   
Sbjct: 196 TPG-STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVK----AKALGATDCLNPR 250

Query: 241 ELRRPEMKNFFK-DMPQPRLALNCVGGKSSTE-LLRQLARGGTMVTYGGMAKQPVVASVS 298
           +L +P  +   +        AL+C GG  + +  L     G    T+ G+A      S  
Sbjct: 251 DLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA----AGSKG 306

Query: 299 LLIFKD-----LKLRGFWLSQWKKDHSPDQFKELI 328
           L IF +       + G +   WK   S D   +L+
Sbjct: 307 LTIFPEELIIGRTINGTFFGGWK---SVDSIPKLV 338


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 25/71 (35%), Positives = 44/71 (61%), Gaps = 2/71 (2%)

Query: 60  LKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNV 119
           ++ +E+A  +  +VR+K+LA  I  +D ++I+G    + + P + G+E    V ++G  V
Sbjct: 36  IEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFPVIVGHEATGIVESIGEGV 93

Query: 120 TGLKPGDWVIP 130
           T +KPGD VIP
Sbjct: 94  TTVKPGDKVIP 104


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 62/238 (26%), Positives = 94/238 (39%), Gaps = 34/238 (14%)

Query: 71  SDVRVKMLAAPINPSDINMIQGNYGFL---------------PELPAVGGNEGVAQVVAV 115
           ++V VK+ AA +NP D+NM  G YG                  E P   G +    V+  
Sbjct: 72  NEVIVKVHAASVNPIDVNMRSG-YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 130

Query: 116 GSNVTGLKPGD--WVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR 173
           G +V   KPGD  W        GT     V S   +   P  +    AA+L     TA+ 
Sbjct: 131 GLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWS 190

Query: 174 MLMDFEQLQ----PGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLK 229
            +     L      G  V+   ++ GVG   IQ+  A       V       Q  S+ ++
Sbjct: 191 AINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCS-----QDASELVR 245

Query: 230 SLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSST---ELLRQLARGGTMVT 284
            LGA+ VI   + +   ++   K +      L+ VGG + T   + L++ + G T VT
Sbjct: 246 KLGADDVI---DYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWS-GATYVT 299


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/95 (27%), Positives = 51/95 (53%), Gaps = 4/95 (4%)

Query: 35  SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNY 94
           S + +  R +A +    G P  + E+   E+A  +  +VR+K++A  +  +++ ++   +
Sbjct: 2   STTGQVIRCKAAILWKPGAPFSIEEV---EVAPPKAKEVRIKVVATGLCGTEMKVLGSKH 58

Query: 95  GFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVI 129
             L   P + G+EG   V ++G  V+ +KPGD VI
Sbjct: 59  LDLL-YPTILGHEGAGIVESIGEGVSTVKPGDKVI 92


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/95 (27%), Positives = 51/95 (53%), Gaps = 4/95 (4%)

Query: 35  SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNY 94
           S + +  R +A +    G P  + E+   E+A  +  +VR+K++A  +  +++ ++   +
Sbjct: 2   STTGQVIRCKAAILWKPGAPFSIEEV---EVAPPKAKEVRIKVVATGLCGTEMKVLGSKH 58

Query: 95  GFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVI 129
             L   P + G+EG   V ++G  V+ +KPGD VI
Sbjct: 59  LDLL-YPTILGHEGAGIVESIGEGVSTVKPGDKVI 92


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 7/96 (7%)

Query: 35  SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQ-GN 93
           +A+A+P  +  +V+G  GD    + L+N  +     ++V ++M +  I  SD++  + G 
Sbjct: 2   AAAAKPNNLSLVVHGP-GD----LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR 56

Query: 94  YG-FLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWV 128
            G F+ + P V G+E    V  VGS+V  LKPGD V
Sbjct: 57  IGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 3/123 (2%)

Query: 105 GNEGVAQVVAVGSNVTGLKPGDWVI---PANAGLGTWRTEAVFSEEALIQVPSDIPLQSA 161
           G E    V+ VGS V+  +P D V+   P ++            E  L+  P  +    A
Sbjct: 63  GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEA 122

Query: 162 ATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDI 221
           A    +   AY  L     L PG SV+     S  G   IQ+A   G + I+      D 
Sbjct: 123 AGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDK 182

Query: 222 QKL 224
           Q L
Sbjct: 183 QCL 185


>gi|110347463 human immunodeficiency virus type I enhancer binding
            protein 2 [Homo sapiens]
          Length = 2446

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 313  SQWKKDHSPDQFKELILTLC-----DLIRRGQLTAPACSQVPLQDYQSALEASMKPFISS 367
            S  KKD S  Q  +L+   C     D ++ G  +  + S    QDY S   +S +PF+ S
Sbjct: 1481 SDIKKDLSRPQKPQLVRQGCASEPKDGLQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPS 1540

Query: 368  KQILT 372
            K++L+
Sbjct: 1541 KEMLS 1545


>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
          Length = 192

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 181 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 240
           ++ G+SV+ + ++ GVG A  QIA A GL+ +       + QK+   +   GA  V    
Sbjct: 9   VKAGESVLVHGASGGVGLAACQIARAYGLKILGTA-GTEEGQKI---VLQNGAHEVFNHR 64

Query: 241 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGG-----------MA 289
           E+   +    +       + +  +   + ++ L  L+ GG ++  G            MA
Sbjct: 65  EVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA 124

Query: 290 KQPVVASVSL 299
           K+  +  V+L
Sbjct: 125 KESSIIGVTL 134


>gi|7705353 three prime repair exonuclease 1 isoform a [Homo
           sapiens]
          Length = 369

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 14/107 (13%)

Query: 244 RPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFK 303
           RPEM       P P L +  +G  + T      +  GT  T G  A  P    +  LIF 
Sbjct: 15  RPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPP--GPMQTLIFF 72

Query: 304 DLKLRGFWLSQWKKDHSPDQFKELILTLCDL-IRRGQLTAPACSQVP 349
           D++  G   SQ K           +  LC L + R  L +P  SQ P
Sbjct: 73  DMEATGLPFSQPK-----------VTELCLLAVHRCALESPPTSQGP 108


>gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo
           sapiens]
          Length = 336

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 16/49 (32%), Positives = 26/49 (53%)

Query: 181 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLK 229
           L  G +V+   +NSG+G+A       LG R I   RDR   ++ + +L+
Sbjct: 40  LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLR 88


>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
          Length = 1178

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 17/80 (21%), Positives = 32/80 (40%)

Query: 19  GLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKML 78
           G+L  + C G +       A P  + +    H   PA  + ++ L+L   +GS     + 
Sbjct: 771 GILGPTACTGESEKHLELLASPLPIPSTFLPHSSTPALHLTVQRLKLPPPQGSSESCTVN 830

Query: 79  AAPINPSDINMIQGNYGFLP 98
                P  +++   N  F+P
Sbjct: 831 IPQQPPGSLSIASPNTAFIP 850


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,271,247
Number of Sequences: 37866
Number of extensions: 629624
Number of successful extensions: 1688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1640
Number of HSP's gapped (non-prelim): 40
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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