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Search of human proteins with 66932986
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932986 filamin-binding LIM protein-1 isoform b [Homo
sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 801 0.0
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 634 0.0
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens] 269 3e-72
gi|58530845 zyxin [Homo sapiens] 143 2e-34
gi|4508047 zyxin [Homo sapiens] 143 2e-34
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 125 5e-29
gi|5031887 LIM domain containing preferred translocation partner... 117 1e-26
gi|7657307 LIM domains containing 1 [Homo sapiens] 117 2e-26
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] 107 1e-23
gi|14249622 ajuba isoform 1 [Homo sapiens] 107 2e-23
gi|109638745 transforming growth factor beta 1 induced transcrip... 100 3e-21
gi|21361591 transforming growth factor beta 1 induced transcript... 100 3e-21
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 89 8e-18
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 89 8e-18
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 86 5e-17
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 86 5e-17
gi|170932518 paxillin isoform 3 [Homo sapiens] 82 6e-16
gi|170932516 paxillin isoform 2 [Homo sapiens] 82 6e-16
gi|170932514 paxillin isoform 1 [Homo sapiens] 82 6e-16
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 80 4e-15
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 78 1e-14
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 78 1e-14
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 78 1e-14
gi|4505001 LIM domain kinase 1 [Homo sapiens] 77 2e-14
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 75 1e-13
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 74 3e-13
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 73 4e-13
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 73 4e-13
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 73 4e-13
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 73 4e-13
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 801 bits (2069), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
Query: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST
Sbjct: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL
Sbjct: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
Query: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 300
ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 300
Query: 301 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 360
GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR
Sbjct: 301 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 360
Query: 361 GGWITRSGDRDHPG 374
GGWITRSGDRDHPG
Sbjct: 361 GGWITRSGDRDHPG 374
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 634 bits (1635), Expect = 0.0
Identities = 298/304 (98%), Positives = 300/304 (98%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 120
Query: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST
Sbjct: 121 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 180
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL
Sbjct: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 240
Query: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 300
ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR
Sbjct: 241 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 300
Query: 301 GLCT 304
+C+
Sbjct: 301 PVCS 304
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 182 ICAFCHKTVSPRE----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233
+C+ C + PR+ +E M R +H C+ C CR L+ Q Y + C+
Sbjct: 302 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 361
Query: 234 PCY 236
PC+
Sbjct: 362 PCH 364
>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
Length = 276
Score = 269 bits (687), Expect = 3e-72
Identities = 127/163 (77%), Positives = 135/163 (82%), Gaps = 1/163 (0%)
Query: 142 PPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMK 201
P P + P G + +P P PA P++ + DICAFCHKTVSPRELAVEAMK
Sbjct: 46 PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL-FNGDICAFCHKTVSPRELAVEAMK 104
Query: 202 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 261
RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA
Sbjct: 105 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 164
Query: 262 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCT 304
FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR +C+
Sbjct: 165 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCS 207
Score = 171 bits (433), Expect = 1e-42
Identities = 83/83 (100%), Positives = 83/83 (100%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNG 83
SPWTTPGRAAATVPAAPMQLFNG
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNG 83
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 182 ICAFCHKTVSPRE----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233
+C+ C + PR+ +E M R +H C+ C CR L+ Q Y + C+
Sbjct: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
Query: 234 PCY 236
PC+
Sbjct: 265 PCH 267
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 143 bits (361), Expect = 2e-34
Identities = 74/206 (35%), Positives = 104/206 (50%), Gaps = 18/206 (8%)
Query: 108 PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPME---- 163
P PP + E P E+ H PPP Q P PGPL E
Sbjct: 309 PQPPSFTYAQQREKPRVQ--------EKQHPVPPPAQNQNQVRSPGA-PGPLTLKEVEEL 359
Query: 164 EELPPPPAEPVEKG-----ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
E+L + +E A ++C CH+ ++ + AV A+ + +H CFTC C +QL
Sbjct: 360 EQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQL 419
Query: 219 AGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
GQ FY +G P CE CY DTLE+C CGE + D ++RA G+A+HP CFTCV CAR +
Sbjct: 420 QGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEG 479
Query: 279 ESFALGSQNEVYCLDDFYRYEKGLCT 304
SF + N +C+ D+++ C+
Sbjct: 480 TSFIVDQANRPHCVPDYHKQYAPRCS 505
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/120 (34%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 173 PVEKGASTDI---CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFY-QKDG 228
P +G TD C C + ++ R L A + YH CFTC C R L G SF +
Sbjct: 431 PYCEGCYTDTLEKCNTCGEPITDRML--RATGKAYHPHCFTCVVCARPLEGTSFIVDQAN 488
Query: 229 RPLCEPCY-QDTLERCGKCGEVV-----RDHIIR--ALGQAFHPSCFTCVTCARCIGDES 280
RP C P Y + RC C E + RD +R AL + FH C+ C C + + E+
Sbjct: 489 RPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEA 548
Score = 58.5 bits (140), Expect = 9e-09
Identities = 54/172 (31%), Positives = 71/172 (41%), Gaps = 32/172 (18%)
Query: 17 LAPPRRDVAVAEEVRQAVCEARRGR--PWEAPAPMKTPEAGLAGRPSPWTTPGRA----A 70
+A PR A++ V A + + P AP P P P P RA
Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60
Query: 71 ATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLI 130
+P P + F PPPP DG+D L PPPPPP E PAP+
Sbjct: 61 GEIPPPPPEDFP--LPPPPLAGDGDDAEGALGGAFPPPPPP----IEESFPPAPLE---- 110
Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI 182
E++ SPPPPP + + GP P+ PPP +P EK +S D+
Sbjct: 111 ---EEIFPSPPPPPEE--------EGGPEAPI-----PPPPQPREKVSSIDL 146
Score = 33.9 bits (76), Expect = 0.24
Identities = 15/63 (23%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233
C+ C + + P + V A+ + +H +C+ C C + L+ + DG LC
Sbjct: 504 CSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCR 563
Query: 234 PCY 236
C+
Sbjct: 564 KCH 566
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 143 bits (361), Expect = 2e-34
Identities = 74/206 (35%), Positives = 104/206 (50%), Gaps = 18/206 (8%)
Query: 108 PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPME---- 163
P PP + E P E+ H PPP Q P PGPL E
Sbjct: 309 PQPPSFTYAQQREKPRVQ--------EKQHPVPPPAQNQNQVRSPGA-PGPLTLKEVEEL 359
Query: 164 EELPPPPAEPVEKG-----ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
E+L + +E A ++C CH+ ++ + AV A+ + +H CFTC C +QL
Sbjct: 360 EQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQL 419
Query: 219 AGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
GQ FY +G P CE CY DTLE+C CGE + D ++RA G+A+HP CFTCV CAR +
Sbjct: 420 QGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEG 479
Query: 279 ESFALGSQNEVYCLDDFYRYEKGLCT 304
SF + N +C+ D+++ C+
Sbjct: 480 TSFIVDQANRPHCVPDYHKQYAPRCS 505
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/120 (34%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 173 PVEKGASTDI---CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFY-QKDG 228
P +G TD C C + ++ R L A + YH CFTC C R L G SF +
Sbjct: 431 PYCEGCYTDTLEKCNTCGEPITDRML--RATGKAYHPHCFTCVVCARPLEGTSFIVDQAN 488
Query: 229 RPLCEPCY-QDTLERCGKCGEVV-----RDHIIR--ALGQAFHPSCFTCVTCARCIGDES 280
RP C P Y + RC C E + RD +R AL + FH C+ C C + + E+
Sbjct: 489 RPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEA 548
Score = 58.5 bits (140), Expect = 9e-09
Identities = 54/172 (31%), Positives = 71/172 (41%), Gaps = 32/172 (18%)
Query: 17 LAPPRRDVAVAEEVRQAVCEARRGR--PWEAPAPMKTPEAGLAGRPSPWTTPGRA----A 70
+A PR A++ V A + + P AP P P P P RA
Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60
Query: 71 ATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLI 130
+P P + F PPPP DG+D L PPPPPP E PAP+
Sbjct: 61 GEIPPPPPEDFP--LPPPPLAGDGDDAEGALGGAFPPPPPP----IEESFPPAPLE---- 110
Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI 182
E++ SPPPPP + + GP P+ PPP +P EK +S D+
Sbjct: 111 ---EEIFPSPPPPPEE--------EGGPEAPI-----PPPPQPREKVSSIDL 146
Score = 33.9 bits (76), Expect = 0.24
Identities = 15/63 (23%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233
C+ C + + P + V A+ + +H +C+ C C + L+ + DG LC
Sbjct: 504 CSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCR 563
Query: 234 PCY 236
C+
Sbjct: 564 KCH 566
>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
Length = 476
Score = 125 bits (315), Expect = 5e-29
Identities = 95/317 (29%), Positives = 133/317 (41%), Gaps = 35/317 (11%)
Query: 46 PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG----GCPPPPPVLDGEDVLPDL 101
P P A G P+P + + PA P+Q+ GC PP
Sbjct: 138 PNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRGCGPPRR---------GA 188
Query: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLI-----ADLEQLHLSPPPPPPQAPAEGPSVQP 156
P P P LP E P S A E +S P + GP V
Sbjct: 189 SQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQV-- 246
Query: 157 GPL-RPMEEELPPPPAEPVE------KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCF 209
PL +P E+EL + V G C C + V V A+ R +H CF
Sbjct: 247 -PLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCF 305
Query: 210 TCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTC 269
C TCR QL GQ FY + R CE CY TLE+C C + + D I+RA+G+A+HP CFTC
Sbjct: 306 VCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFTC 365
Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTGWGAGTGRDPSRVK-------ELSL 322
V C R + F + + ++++C++DF+R C+ G +P + + + S
Sbjct: 366 VVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSF 425
Query: 323 SPGCWARVSCLLVYYKE 339
GC+ C L+ E
Sbjct: 426 HIGCYKCEECGLLLSSE 442
Score = 51.2 bits (121), Expect = 1e-06
Identities = 43/153 (28%), Positives = 63/153 (41%), Gaps = 26/153 (16%)
Query: 178 ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPL--CEPC 235
A+ + CA C + + R L AM + YH CFTC C R L G F + E
Sbjct: 334 ATLEKCATCSQPILDRIL--RAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDF 391
Query: 236 YQDTLERCGKCGEVV-----RDHIIR--ALGQAFHPSCFTCVTCARCIGDESFALGSQNE 288
++ RC CG + ++ +R AL ++FH C+ C C + E G
Sbjct: 392 HRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSE----GECQG 447
Query: 289 VYCLDDFYRYEKGLCTGWGAGTGRDPSRVKELS 321
Y LD + C+ W R++ELS
Sbjct: 448 CYPLDGHILCK--ACSAW---------RIQELS 469
>gi|5031887 LIM domain containing preferred translocation partner in
lipoma [Homo sapiens]
Length = 612
Score = 117 bits (294), Expect = 1e-26
Identities = 59/171 (34%), Positives = 85/171 (49%), Gaps = 11/171 (6%)
Query: 138 LSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDI-----------CAFC 186
+S P PP P G S Q GP P E + K D+ CA C
Sbjct: 360 VSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARC 419
Query: 187 HKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKC 246
+ V AM + +H CFTC C +L GQ FY + + CEPCY +TLE+C C
Sbjct: 420 GENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVC 479
Query: 247 GEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
+ + + I+RA G+A+HP CFTCV C R + F + + ++C++DF++
Sbjct: 480 SKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHK 530
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 24/124 (19%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF-------------YQKDGR 229
C C K + R L A + YH CFTC C R L G F + K
Sbjct: 476 CNVCSKPIMERIL--RATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFA 533
Query: 230 PLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEV 289
P C C + + G+ E VR I AL + FH C+ C C + + G
Sbjct: 534 PRCSVCKEPIMPAPGQ-EETVR---IVALDRDFHVHCYRCEDCGGLLSE-----GDNQGC 584
Query: 290 YCLD 293
Y LD
Sbjct: 585 YPLD 588
Score = 36.2 bits (82), Expect = 0.049
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 86 PPPPPVLDGEDVLPDLDLLPPPPPP----------PPVLLPSEE-----EAPAPMGASLI 130
PPPPP LD LP + PPPPP P EE +A S++
Sbjct: 69 PPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSIL 128
Query: 131 ADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
ADLE SP P P + G + P P+
Sbjct: 129 ADLE--CSSPYKPRPPQSSTGSTASPPVSTPV 158
Score = 36.2 bits (82), Expect = 0.049
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 183 CAFCHKTVSP-----RELAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
C+ C + + P + + A+ R +H C+ C C L+ Q Y DG LC+
Sbjct: 536 CSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKT 595
Query: 235 C 235
C
Sbjct: 596 C 596
Score = 31.6 bits (70), Expect = 1.2
Identities = 40/167 (23%), Positives = 58/167 (34%), Gaps = 51/167 (30%)
Query: 47 APMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL--------FNGGCPPPPPV------- 91
AP+ P+ + +P+ PG +P P L +G PPPPP+
Sbjct: 46 APVVAPKP----KYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKV 101
Query: 92 ---------------LDGE-----DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA 131
LD E +L DL+ P P PP +P P+ +
Sbjct: 102 QGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASP-PVSTPVTG 160
Query: 132 DLEQLHLSPPP---------PPPQAPAEGP-SVQP-GPLRPMEEELP 167
+ + PP P AP GP V P G L+P + +P
Sbjct: 161 HKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVP 207
>gi|7657307 LIM domains containing 1 [Homo sapiens]
Length = 676
Score = 117 bits (293), Expect = 2e-26
Identities = 80/269 (29%), Positives = 118/269 (43%), Gaps = 21/269 (7%)
Query: 60 PSPWTTPGRAAATVPAAPMQL---FNGGCPPPPPVLDGEDVLPDLDLLPPPPPPP---PV 113
P PW G + +AP +G P L + DL P P PV
Sbjct: 333 PQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPV 392
Query: 114 L--LPSEEEAPAPMGASLIADLEQLHL-SPPPPPPQAPAE----GPSVQPGPLRPMEEEL 166
+ LP P+G S L + L SP P + P + GP ++P E L
Sbjct: 393 MSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLEAL 452
Query: 167 PPPPAEPVEKGASTDI---CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF 223
++ D C C K V A +AM YH CFTC C R+L G++F
Sbjct: 453 TQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAF 512
Query: 224 YQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
Y +G+ CE + Q + +RC CG ++ D I++ALG+++HP CF CV C C+
Sbjct: 513 YFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDG 572
Query: 279 ESFALGSQNEVYCLDDFYRYEKGLCTGWG 307
F + S+N++YC+ D+++ C G
Sbjct: 573 VPFTVDSENKIYCVRDYHKVLAPKCAACG 601
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 11/110 (10%)
Query: 179 STDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF-YQKDGRPLCEPCYQ 237
S D C C + ++ ++A+ + YH CF C C L G F + + C Y
Sbjct: 533 SADRCFLCGHLIM--DMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYH 590
Query: 238 DTLE-RCGKCGEVV-----RDHIIR--ALGQAFHPSCFTCVTCARCIGDE 279
L +C CG + D IR ++ + +H C+ C C + DE
Sbjct: 591 KVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDE 640
Score = 37.0 bits (84), Expect = 0.029
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 8/68 (11%)
Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQL---AGQSFYQKDGRPLCEP 234
CA C + P E + V +M R YH +C+ C C +L G Y + C
Sbjct: 597 CAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHS 656
Query: 235 CYQDTLER 242
C+ LE+
Sbjct: 657 CHVKRLEK 664
>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
Length = 430
Score = 107 bits (268), Expect = 1e-23
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 25/203 (12%)
Query: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP 161
D LPP P P P E PAP P P P GPS L
Sbjct: 158 DFLPPGACPAPARSP-EPAGPAPFPL------------PALPLPPGREGGPSAAERRLEA 204
Query: 162 MEEELPPPPAEPVEKGASTD---ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
+ EL +E + D IC C + + A +AM YH CFTC +C R+L
Sbjct: 205 LTRELE----RALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRL 260
Query: 219 AGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCA 273
G++FY + C+ + Q T ++C CG ++ + I++ALG+++HP CF C C
Sbjct: 261 RGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCN 320
Query: 274 RCIGDESFALGSQNEVYCLDDFY 296
C+ F + +N +YC+ D++
Sbjct: 321 ECLDGVPFTVDVENNIYCVRDYH 343
Score = 40.0 bits (92), Expect = 0.003
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLAGQS---FYQKDGRPLCEP 234
CA C + + P + + V +M R YH C+ C C QL+G+ Y G LC
Sbjct: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRR 409
Query: 235 CYQDTLE 241
C+ L+
Sbjct: 410 CHLRRLQ 416
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 107 bits (266), Expect = 2e-23
Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 15/172 (8%)
Query: 151 GPSVQPGPLRPMEEELPPPP----------AEPVEKGASTDICAFCHKTVSPRELAVEAM 200
G +P + P E PP P EP + C C+K + + A +A+
Sbjct: 296 GARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355
Query: 201 KRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHII 255
YH QCF C +C R L ++FY +G CE Y Q+ E+C CG ++ + I+
Sbjct: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415
Query: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTGWG 307
+A+G+++HP CF C+ C +C+ F + N+VYC+ D+++ C G
Sbjct: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACG 467
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/110 (28%), Positives = 46/110 (41%), Gaps = 19/110 (17%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF-------------YQKDGR 229
C C + E ++AM + YH CF C C + L G F Y K+
Sbjct: 403 CCVCGHLIL--EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYA 460
Query: 230 PLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDE 279
P C C Q L G C ++VR + ++ + +H C+ C C + DE
Sbjct: 461 PKCAACGQPILPSEG-CEDIVR---VISMDRDYHFECYHCEDCRMQLSDE 506
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
Query: 235 CYQDTL 240
C+ L
Sbjct: 523 CHMQRL 528
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 100 bits (248), Expect = 3e-21
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 30/216 (13%)
Query: 115 LPSEEEAPAPMGASLIADLE----QLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPP 170
LPS P ++ A LE LS PA GP+ QP + E P PP
Sbjct: 138 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPT-QPPVVSSTNEGSPSPP 196
Query: 171 AEPVEKGA--------------------STDICAFCHKTVSPRELAVEAMKRQYHAQCFT 210
EP KG+ + +C C+K ++ + V A+ R +H + F
Sbjct: 197 -EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQ--VVTALGRAWHPEHFV 253
Query: 211 CRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTC 269
C C L G SF++KDG P C CY + RCG C + +R ++ ALG +HP F C
Sbjct: 254 CGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCC 313
Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
V+C GDE F + YC DF + C G
Sbjct: 314 VSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQG 348
Score = 70.5 bits (171), Expect = 2e-12
Identities = 33/86 (38%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 255
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 358 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 417
Query: 256 RALGQAFHPSCFTCVTCARCIGDESF 281
ALG+ FHP FTC C R + SF
Sbjct: 418 SALGRRFHPDHFTCTFCLRPLTKGSF 443
Score = 65.1 bits (157), Expect = 1e-10
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 241
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 287 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 344
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKG 301
RC C + D+ I AL +HP CF C C SF + C + F+
Sbjct: 345 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 403
Query: 302 LCTGWGAG-TGR 312
LC G TGR
Sbjct: 404 LCATCGLPVTGR 415
Score = 49.3 bits (116), Expect = 6e-06
Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY 236
+CA C V+ R V A+ R++H FTC C R L SF ++ G+P C+PC+
Sbjct: 404 LCATCGLPVTGR--CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 100 bits (248), Expect = 3e-21
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 30/216 (13%)
Query: 115 LPSEEEAPAPMGASLIADLE----QLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPP 170
LPS P ++ A LE LS PA GP+ QP + E P PP
Sbjct: 121 LPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPT-QPPVVSSTNEGSPSPP 179
Query: 171 AEPVEKGA--------------------STDICAFCHKTVSPRELAVEAMKRQYHAQCFT 210
EP KG+ + +C C+K ++ + V A+ R +H + F
Sbjct: 180 -EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQ--VVTALGRAWHPEHFV 236
Query: 211 CRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTC 269
C C L G SF++KDG P C CY + RCG C + +R ++ ALG +HP F C
Sbjct: 237 CGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCC 296
Query: 270 VTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
V+C GDE F + YC DF + C G
Sbjct: 297 VSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQG 331
Score = 70.5 bits (171), Expect = 2e-12
Identities = 33/86 (38%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 197 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 255
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 400
Query: 256 RALGQAFHPSCFTCVTCARCIGDESF 281
ALG+ FHP FTC C R + SF
Sbjct: 401 SALGRRFHPDHFTCTFCLRPLTKGSF 426
Score = 65.1 bits (157), Expect = 1e-10
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 241
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 270 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKG 301
RC C + D+ I AL +HP CF C C SF + C + F+
Sbjct: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 386
Query: 302 LCTGWGAG-TGR 312
LC G TGR
Sbjct: 387 LCATCGLPVTGR 398
Score = 49.3 bits (116), Expect = 6e-06
Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY 236
+CA C V+ R V A+ R++H FTC C R L SF ++ G+P C+PC+
Sbjct: 387 LCATCGLPVTGR--CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 88.6 bits (218), Expect = 8e-18
Identities = 75/264 (28%), Positives = 104/264 (39%), Gaps = 27/264 (10%)
Query: 45 APAPMKTPEAGLAGRPSPWTT--PGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLD 102
+PAP TP A PSP T P A A P+ P +N P P G
Sbjct: 322 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS-PAPNYN---PAPSVAYSGGPA----- 372
Query: 103 LLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
P PP V S + AP ++ + L P P PA GP V P +
Sbjct: 373 --EPASRPPWVTDDSFSQKFAPGKSTTSISKQTL---PRGGPAYTPA-GPQVPPLARGTV 426
Query: 163 EEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS 222
+ AE + T +C C+ + R + AM R +H + FTC C+ LA
Sbjct: 427 QR------AERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 478
Query: 223 FYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
F ++ CE CY+ C KC + ++ AL Q +H +CF C C + G+ F
Sbjct: 479 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 538
Query: 282 ALGSQNEVYCLDDFYRYEKGLCTG 305
+ E YC D+ C G
Sbjct: 539 HM-EDGEPYCEKDYINLFSTKCHG 561
Score = 63.2 bits (152), Expect = 4e-10
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 241
+CA C+ + + A+++ +H CF C C++ F+ +DG P CE Y +
Sbjct: 499 LCAKCNTKIMGE--VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 556
Query: 242 -RCGKCGEVVR--DHIIRALGQAFHPSCFTCVTC 272
+C C V D I ALG +H +CF C C
Sbjct: 557 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVC 590
Score = 57.8 bits (138), Expect = 2e-08
Identities = 68/283 (24%), Positives = 96/283 (33%), Gaps = 48/283 (16%)
Query: 38 RRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPP---PPVLDG 94
RR RP A +P + P+ T+ A P + P P
Sbjct: 249 RRSRP---QASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 305
Query: 95 EDVLPDLDLLPPP--PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGP 152
P + P P P P P PS A P +P P P P+ P
Sbjct: 306 YSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTY--------TPSPAPAYTPSPAP 357
Query: 153 SVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCR 212
+ P P PAEP + +F K +P + K+
Sbjct: 358 NYNPAP----SVAYSGGPAEPASRPPWVTDDSFSQK-FAPGKSTTSISKQ---------- 402
Query: 213 TCRRQLAGQSFYQKDGRPLCEPCYQDTLER------------CGKCGEVVRDHIIRALGQ 260
T R G Y G P P + T++R CG C V+R + A+G+
Sbjct: 403 TLPR---GGPAYTPAG-PQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGR 458
Query: 261 AFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLC 303
++HP FTC C + D F + QN VYC + ++ LC
Sbjct: 459 SWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFFAPLC 500
Score = 46.2 bits (108), Expect = 5e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
C C V + +EA+ +H CF C C L GQ FY K RPLC+
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 88.6 bits (218), Expect = 8e-18
Identities = 75/264 (28%), Positives = 104/264 (39%), Gaps = 27/264 (10%)
Query: 45 APAPMKTPEAGLAGRPSPWTT--PGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLD 102
+PAP TP A PSP T P A A P+ P +N P P G
Sbjct: 432 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS-PAPNYN---PAPSVAYSGGPA----- 482
Query: 103 LLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
P PP V S + AP ++ + L P P PA GP V P +
Sbjct: 483 --EPASRPPWVTDDSFSQKFAPGKSTTSISKQTL---PRGGPAYTPA-GPQVPPLARGTV 536
Query: 163 EEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS 222
+ AE + T +C C+ + R + AM R +H + FTC C+ LA
Sbjct: 537 QR------AERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 588
Query: 223 FYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
F ++ CE CY+ C KC + ++ AL Q +H +CF C C + G+ F
Sbjct: 589 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 648
Query: 282 ALGSQNEVYCLDDFYRYEKGLCTG 305
+ E YC D+ C G
Sbjct: 649 HM-EDGEPYCEKDYINLFSTKCHG 671
Score = 63.2 bits (152), Expect = 4e-10
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 241
+CA C+ + + A+++ +H CF C C++ F+ +DG P CE Y +
Sbjct: 609 LCAKCNTKIMGE--VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 666
Query: 242 -RCGKCGEVVR--DHIIRALGQAFHPSCFTCVTC 272
+C C V D I ALG +H +CF C C
Sbjct: 667 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVC 700
Score = 62.0 bits (149), Expect = 8e-10
Identities = 71/306 (23%), Positives = 103/306 (33%), Gaps = 48/306 (15%)
Query: 18 APPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKT---PEAGLAGRPSPWTTPGRAAATVP 74
+PP A + A A P ++P P + P + P+ T+ A
Sbjct: 333 SPPLATAAAHTAIASASTTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPA 392
Query: 75 AAPMQLFNGGCPPP---PPVLDGEDVLPDLDLLPPP--PPPPPVLLPSEEEAPAPMGASL 129
P + P P P + P P P P P PS A P
Sbjct: 393 PKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPT 452
Query: 130 IADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKT 189
+P P P P+ P+ P P PAEP + +F K
Sbjct: 453 Y--------TPSPAPAYTPSPAPNYNPAP----SVAYSGGPAEPASRPPWVTDDSFSQK- 499
Query: 190 VSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER------- 242
+P + K+ T R G Y G P P + T++R
Sbjct: 500 FAPGKSTTSISKQ----------TLPR---GGPAYTPAG-PQVPPLARGTVQRAERFPAS 545
Query: 243 -----CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
CG C V+R + A+G+++HP FTC C + D F + QN VYC + +
Sbjct: 546 SRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQ 604
Query: 298 YEKGLC 303
+ LC
Sbjct: 605 FFAPLC 610
Score = 46.2 bits (108), Expect = 5e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
C C V + +EA+ +H CF C C L GQ FY K RPLC+
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Score = 29.3 bits (64), Expect = 6.0
Identities = 24/106 (22%), Positives = 37/106 (34%), Gaps = 9/106 (8%)
Query: 106 PPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP---- 161
PP P ++P +++ SL+A P P P P+ P RP
Sbjct: 94 PPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFS 153
Query: 162 --MEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYH 205
E P PP + S + + P+ L + RQY+
Sbjct: 154 SLAEASDPGPPRASLRAKTSPE---GARDLLGPKALPGSSQPRQYN 196
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 85.9 bits (211), Expect = 5e-17
Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 4/150 (2%)
Query: 157 GPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRR 216
G +P +++ AE + G T +CA C++ + R + A+ + +H + F C C+
Sbjct: 285 GQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCKN 342
Query: 217 QLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARC 275
+A F ++ G CE CY+ CG+C + +I AL Q +H SCF CV C +
Sbjct: 343 TMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKP 402
Query: 276 IGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
I + F L E YC D+Y +C G
Sbjct: 403 IRNNVFHL-EDGEPYCETDYYALFGTICHG 431
Score = 58.5 bits (140), Expect = 9e-09
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + + A+K+ +H CF C C + + F+ +DG P CE Y
Sbjct: 370 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
Query: 243 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 281
C C + D + ALG +H +CF C C + ++F
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 469
Score = 46.2 bits (108), Expect = 5e-05
Identities = 18/52 (34%), Positives = 28/52 (53%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
IC C + ++ +EA+ +H CF C C L GQ+F+ K +PLC+
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 85.9 bits (211), Expect = 5e-17
Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 4/150 (2%)
Query: 157 GPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRR 216
G +P +++ AE + G T +CA C++ + R + A+ + +H + F C C+
Sbjct: 394 GQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCKN 451
Query: 217 QLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARC 275
+A F ++ G CE CY+ CG+C + +I AL Q +H SCF CV C +
Sbjct: 452 TMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKP 511
Query: 276 IGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
I + F L E YC D+Y +C G
Sbjct: 512 IRNNVFHL-EDGEPYCETDYYALFGTICHG 540
Score = 58.5 bits (140), Expect = 9e-09
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + + A+K+ +H CF C C + + F+ +DG P CE Y
Sbjct: 479 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536
Query: 243 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 281
C C + D + ALG +H +CF C C + ++F
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 578
Score = 46.2 bits (108), Expect = 5e-05
Identities = 18/52 (34%), Positives = 28/52 (53%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
IC C + ++ +EA+ +H CF C C L GQ+F+ K +PLC+
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 82.4 bits (202), Expect = 6e-16
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
SPP PP+ ++ S+ L ++ +L V KG +C C K ++ + V
Sbjct: 155 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 204
Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
AM + +H + F C C+ ++ ++F+++DG+P CE Y + RC C + D ++ A
Sbjct: 205 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 264
Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
L + +HP F C C G E F + YC D++ C G
Sbjct: 265 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGG 311
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 250 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 307
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKG 301
+CG C + ++ I AL +HP CF C C + SF + YC ++
Sbjct: 308 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 366
Query: 302 LCTG 305
LC+G
Sbjct: 367 LCSG 370
Score = 63.9 bits (154), Expect = 2e-10
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 309 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
C C + + I A+ + FHP F C C + + +F ++ YC + F +
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLK 421
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 82.4 bits (202), Expect = 6e-16
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
SPP PP+ ++ S+ L ++ +L V KG +C C K ++ + V
Sbjct: 288 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 337
Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
AM + +H + F C C+ ++ ++F+++DG+P CE Y + RC C + D ++ A
Sbjct: 338 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 397
Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
L + +HP F C C G E F + YC D++ C G
Sbjct: 398 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGG 444
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 383 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 440
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKG 301
+CG C + ++ I AL +HP CF C C + SF + YC ++
Sbjct: 441 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 499
Query: 302 LCTG 305
LC+G
Sbjct: 500 LCSG 503
Score = 63.9 bits (154), Expect = 2e-10
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 442 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
C C + + I A+ + FHP F C C + + +F ++ YC + F +
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLK 554
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 82.4 bits (202), Expect = 6e-16
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 139 SPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVE 198
SPP PP+ ++ S+ L ++ +L V KG +C C K ++ + V
Sbjct: 322 SPPGGPPKPGSQLDSM----LGSLQSDLNKLGVATVAKG----VCGACKKPIAGQ--VVT 371
Query: 199 AMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRA 257
AM + +H + F C C+ ++ ++F+++DG+P CE Y + RC C + D ++ A
Sbjct: 372 AMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTA 431
Query: 258 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
L + +HP F C C G E F + YC D++ C G
Sbjct: 432 LDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGG 478
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 241
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 417 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 474
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKG 301
+CG C + ++ I AL +HP CF C C + SF + YC ++
Sbjct: 475 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 533
Query: 302 LCTG 305
LC+G
Sbjct: 534 LCSG 537
Score = 63.9 bits (154), Expect = 2e-10
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 4/116 (3%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 241
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 476 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 242 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 297
C C + + I A+ + FHP F C C + + +F ++ YC + F +
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLK 588
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 79.7 bits (195), Expect = 4e-15
Identities = 39/123 (31%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Query: 160 RPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA 219
R + PPP + + +C C SP E V + YH CF C C R
Sbjct: 16 RRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFP 75
Query: 220 GQSFYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGD 278
FY+ +GR CE +Q CG CGE + +I+A+ +HP CF C C + D
Sbjct: 76 EGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELAD 135
Query: 279 ESF 281
F
Sbjct: 136 LGF 138
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 173 PVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLC 232
P IC C + + R V A+ +Q+H + F C C + G Y+K G C
Sbjct: 212 PCHDKMGVPICGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 269
Query: 233 EPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 272
E Y + C C V+ ++ AL +A+ SCF+C TC
Sbjct: 270 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 310
Score = 62.8 bits (151), Expect = 5e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H CF C C +LA F + GR LC PC+ +
Sbjct: 100 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 157
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCL 292
C +C V+ + + A+HP F C C + + E+ L + E+YCL
Sbjct: 158 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL--KGELYCL 211
Score = 52.4 bits (124), Expect = 7e-07
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 176 KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC 235
KG IC CH + + L + YH F C C ++L ++ K G C PC
Sbjct: 157 KGLGKYICQRCHLVIDEQPLMFRS--DAYHPDHFNCTHCGKELTAEARELK-GELYCLPC 213
Query: 236 YQDT-LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
+ + CG C + ++ ALG+ +H F C C +
Sbjct: 214 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEK 253
Score = 38.1 bits (87), Expect = 0.013
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA-GQSFYQKDGRPLCEPCYQ 237
D+C C + V A+ + + CF+C TC +L F + D +P+C+ CY+
Sbjct: 279 DVCYNCSHVIEGD--VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYE 334
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 77.8 bits (190), Expect = 1e-14
Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 167 PPPPAEPVEKGASTDICAFCHKTVSP-RELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQ 225
P P P EK CHK P + + + +H +CFTC+ C LA F+
Sbjct: 25 PQDPHHPSEKPV-----IHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI 79
Query: 226 KDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
K+G LC YQ RC CGE V ++ ALG+ +HP+CF C C R
Sbjct: 80 KNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKR 129
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Query: 168 PPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKD 227
P + P E S++ CA C + + + A+ A+ +Q+H CF C++C + L G+ + KD
Sbjct: 152 PMSSSPKETTFSSN-CAGCGRDIKNGQ-ALLALDKQWHLGCFKCKSCGKVLTGE-YISKD 208
Query: 228 GRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCI--GDESFALG 284
G P CE YQ +C C + + ++ A + +HPSC C C + G+E + G
Sbjct: 209 GAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 268
Query: 285 S 285
S
Sbjct: 269 S 269
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 1/90 (1%)
Query: 243 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGL 302
C KCGE + ++R + FH CFTC C + F + E C D+ R
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI-KNGEYLCTLDYQRMYGTR 97
Query: 303 CTGWGAGTGRDPSRVKELSLSPGCWARVSC 332
C G G + + P C+A C
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTIC 127
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 77.8 bits (190), Expect = 1e-14
Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 167 PPPPAEPVEKGASTDICAFCHKTVSP-RELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQ 225
P P P EK CHK P + + + +H +CFTC+ C LA F+
Sbjct: 25 PQDPHHPSEKPV-----IHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI 79
Query: 226 KDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
K+G LC YQ RC CGE V ++ ALG+ +HP+CF C C R
Sbjct: 80 KNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKR 129
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Query: 168 PPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKD 227
P + P E S++ CA C + + + A+ A+ +Q+H CF C++C + L G+ + KD
Sbjct: 152 PMSSSPKETTFSSN-CAGCGRDIKNGQ-ALLALDKQWHLGCFKCKSCGKVLTGE-YISKD 208
Query: 228 GRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCI--GDESFALG 284
G P CE YQ +C C + + ++ A + +HPSC C C + G+E + G
Sbjct: 209 GAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 268
Query: 285 S 285
S
Sbjct: 269 S 269
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 1/90 (1%)
Query: 243 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGL 302
C KCGE + ++R + FH CFTC C + F + E C D+ R
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI-KNGEYLCTLDYQRMYGTR 97
Query: 303 CTGWGAGTGRDPSRVKELSLSPGCWARVSC 332
C G G + + P C+A C
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTIC 127
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 77.8 bits (190), Expect = 1e-14
Identities = 40/110 (36%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 167 PPPPAEPVEKGASTDICAFCHKTVSP-RELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQ 225
P P P EK CHK P + + + +H +CFTC+ C LA F+
Sbjct: 85 PQDPHHPSEKPV-----IHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI 139
Query: 226 KDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
K+G LC YQ RC CGE V ++ ALG+ +HP+CF C C R
Sbjct: 140 KNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKR 189
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Query: 168 PPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKD 227
P + P E S++ CA C + + + A+ A+ +Q+H CF C++C + L G+ + KD
Sbjct: 212 PMSSSPKETTFSSN-CAGCGRDIKNGQ-ALLALDKQWHLGCFKCKSCGKVLTGE-YISKD 268
Query: 228 GRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCI--GDESFALG 284
G P CE YQ +C C + + ++ A + +HPSC C C + G+E + G
Sbjct: 269 GAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 328
Query: 285 S 285
S
Sbjct: 329 S 329
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 1/90 (1%)
Query: 243 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGL 302
C KCGE + ++R + FH CFTC C + F + E C D+ R
Sbjct: 99 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFI-KNGEYLCTLDYQRMYGTR 157
Query: 303 CTGWGAGTGRDPSRVKELSLSPGCWARVSC 332
C G G + + P C+A C
Sbjct: 158 CHGCGEFVEGEVVTALGKTYHPNCFACTIC 187
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 77.4 bits (189), Expect = 2e-14
Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 5/126 (3%)
Query: 175 EKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEP 234
E+G+ +CA C + + + ++A+ +HA CF C C L+ Q +Y+KDG+ C+
Sbjct: 17 EEGSELPVCASCGQRIYDGQY-LQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFCKK 74
Query: 235 CYQDTL-ERCGKCGEVVRDHIIRALGQA-FHPSCFTCVTCARCIGD-ESFALGSQNEVYC 291
Y E C C E + ++ G+ +HP CF C+TC IGD +++ L +++YC
Sbjct: 75 DYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
Query: 292 LDDFYR 297
+Y+
Sbjct: 135 GHCYYQ 140
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 75.1 bits (183), Expect = 1e-13
Identities = 79/335 (23%), Positives = 113/335 (33%), Gaps = 88/335 (26%)
Query: 39 RGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPPP---PVLDGE 95
+ +P +A AP A P +T + A P G PPP P +G+
Sbjct: 88 QSKPQKASAP--------AADPPRYTFAPSVSLNKTARPF-----GAPPPADSAPQQNGQ 134
Query: 96 DVLPDLDLLPPPPPPPPVLLPSEEEAPAP--------------MGASLIADLEQLHL--S 139
+ P L P ++ +E+ P P G + D ++ HL S
Sbjct: 135 PLRP----LVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKS 190
Query: 140 PPPPPPQAPAEGPSVQ----PGPLRPMEEELPP------------------------PPA 171
P +APA S PGP P PP PA
Sbjct: 191 SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPA 250
Query: 172 EPV--------------------EKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTC 211
P T +C CHK + R L A+ YH + F C
Sbjct: 251 TPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLV--ALGHAYHPEEFVC 308
Query: 212 RTCRRQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCV 270
C + L F+++ G C PCY C KC + + I+ AL +H CFTC
Sbjct: 309 SQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCA 368
Query: 271 TCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTG 305
C I + +F + + YC D+ + C G
Sbjct: 369 ACKTPIRNRAFYM-EEGVPYCERDYEKMFGTKCHG 402
Score = 65.9 bits (159), Expect = 6e-11
Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%)
Query: 169 PPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDG 228
PP V S CA C K ++ + A+K +H CFTC C+ + ++FY ++G
Sbjct: 330 PPCYDVRYAPS---CAKCKKKITGE--IMHALKMTWHVHCFTCAACKTPIRNRAFYMEEG 384
Query: 229 RPLCEPCYQDTL-ERCGKCGEVV--RDHIIRALGQAFHPSCFTCVTC 272
P CE Y+ +C C + D + ALG ++H +CF C C
Sbjct: 385 VPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
Score = 43.9 bits (102), Expect = 2e-04
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
C C + + +EA+ +H CF C C+ L G++FY K RPLC+
Sbjct: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 73.6 bits (179), Expect = 3e-13
Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C +P E V + YH QCF C C +Q FY+ +GR CE +Q
Sbjct: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 131
Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
C +CGE + +I+A+ ++HP CF C C + D F
Sbjct: 132 CCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 171
Score = 60.1 bits (144), Expect = 3e-09
Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H +CF C C+ LA F + GR LC PC+ R
Sbjct: 133 CHQCGEFIIGR--VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 190
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTC------ARCIGDESFAL 283
C KC ++ + + +HP F C C RC G E A+
Sbjct: 191 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSDCRCTGAERGAI 243
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 73.2 bits (178), Expect = 4e-13
Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 241
+C C SP E V + YH CF C C R FY+ +GR CE +Q
Sbjct: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95
Query: 242 R-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
CG CGE + +I+A+ +HP CF C C + D F
Sbjct: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF 136
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 173 PVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLC 232
P IC C + + R V A+ +Q+H + F C C + G Y+K G C
Sbjct: 210 PCHDKMGVPICGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 267
Query: 233 EPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 272
E Y + C C V+ ++ AL +A+ SCF+C TC
Sbjct: 268 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 308
Score = 62.8 bits (151), Expect = 5e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H CF C C +LA F + GR LC PC+ +
Sbjct: 98 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCL 292
C +C V+ + + A+HP F C C + + E+ L + E+YCL
Sbjct: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL--KGELYCL 209
Score = 52.4 bits (124), Expect = 7e-07
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 176 KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC 235
KG IC CH + + L + YH F C C ++L ++ K G C PC
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRS--DAYHPDHFNCTHCGKELTAEARELK-GELYCLPC 211
Query: 236 YQDT-LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
+ + CG C + ++ ALG+ +H F C C +
Sbjct: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEK 251
Score = 38.1 bits (87), Expect = 0.013
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA-GQSFYQKDGRPLCEPCYQ 237
D+C C + V A+ + + CF+C TC +L F + D +P+C+ CY+
Sbjct: 277 DVCYNCSHVIEGD--VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYE 332
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 73.2 bits (178), Expect = 4e-13
Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 241
+C C SP E V + YH CF C C R FY+ +GR CE +Q
Sbjct: 9 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 242 R-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
CG CGE + +I+A+ +HP CF C C + D F
Sbjct: 69 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF 109
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 173 PVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLC 232
P IC C + + R V A+ +Q+H + F C C + G Y+K G C
Sbjct: 183 PCHDKMGVPICGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 240
Query: 233 EPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 272
E Y + C C V+ ++ AL +A+ SCF+C TC
Sbjct: 241 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 281
Score = 62.8 bits (151), Expect = 5e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H CF C C +LA F + GR LC PC+ +
Sbjct: 71 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 128
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCL 292
C +C V+ + + A+HP F C C + + E+ L + E+YCL
Sbjct: 129 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL--KGELYCL 182
Score = 52.4 bits (124), Expect = 7e-07
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 176 KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC 235
KG IC CH + + L + YH F C C ++L ++ K G C PC
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRS--DAYHPDHFNCTHCGKELTAEARELK-GELYCLPC 184
Query: 236 YQDT-LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
+ + CG C + ++ ALG+ +H F C C +
Sbjct: 185 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEK 224
Score = 38.1 bits (87), Expect = 0.013
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA-GQSFYQKDGRPLCEPCYQ 237
D+C C + V A+ + + CF+C TC +L F + D +P+C+ CY+
Sbjct: 250 DVCYNCSHVIEGD--VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYE 305
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 73.2 bits (178), Expect = 4e-13
Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 241
+C C SP E V + YH CF C C R FY+ +GR CE +Q
Sbjct: 14 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 73
Query: 242 R-CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
CG CGE + +I+A+ +HP CF C C + D F
Sbjct: 74 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF 114
Score = 65.5 bits (158), Expect = 8e-11
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 173 PVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLC 232
P IC C + + R V A+ +Q+H + F C C + G Y+K G C
Sbjct: 188 PCHDKMGVPICGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 245
Query: 233 EPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 272
E Y + C C V+ ++ AL +A+ SCF+C TC
Sbjct: 246 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 286
Score = 62.8 bits (151), Expect = 5e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H CF C C +LA F + GR LC PC+ +
Sbjct: 76 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 133
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCL 292
C +C V+ + + A+HP F C C + + E+ L + E+YCL
Sbjct: 134 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL--KGELYCL 187
Score = 52.4 bits (124), Expect = 7e-07
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 176 KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC 235
KG IC CH + + L + YH F C C ++L ++ K G C PC
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRS--DAYHPDHFNCTHCGKELTAEARELK-GELYCLPC 189
Query: 236 YQDT-LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
+ + CG C + ++ ALG+ +H F C C +
Sbjct: 190 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEK 229
Score = 38.1 bits (87), Expect = 0.013
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA-GQSFYQKDGRPLCEPCYQ 237
D+C C + V A+ + + CF+C TC +L F + D +P+C+ CY+
Sbjct: 255 DVCYNCSHVIEGD--VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYE 310
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 73.2 bits (178), Expect = 4e-13
Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C +P E V + YH QCF C C +Q FY+ +GR CE +Q
Sbjct: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 69
Query: 243 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
C +CGE + +I+A+ ++HP CF C C + D F
Sbjct: 70 CCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 109
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 173 PVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLC 232
P IC C + + R V AM +Q+H + F C C + G Y++ G C
Sbjct: 183 PCHDKMGVPICGACRRPIEGR--VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
Query: 233 EPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 272
E Y + C C V+ ++ AL +A+ +CF C TC
Sbjct: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281
Score = 62.4 bits (150), Expect = 6e-10
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242
C C + + R ++AM +H +CF C C+ LA F + GR LC PC+ R
Sbjct: 71 CHQCGEFIIGR--VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128
Query: 243 ------CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCL 292
C KC ++ + + +HP F C C + + ++ L + E+YCL
Sbjct: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGELYCL 182
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 176 KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC 235
+G IC CH + + L + YH F C C ++L + K G C PC
Sbjct: 128 RGLGKYICQKCHAIIDEQPLIFK--NDPYHPDHFNCANCGKELTADARELK-GELYCLPC 184
Query: 236 YQDT-LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 274
+ + CG C + ++ A+G+ +H F C C +
Sbjct: 185 HDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEK 224
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 181 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLA-GQSFYQKDGRPLCEPCYQ 237
D+C C++ + V A+ + + CF C TC +L F + D +P+C+ CY+
Sbjct: 250 DVCFHCNRVIEGD--VVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYE 305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,828,313
Number of Sequences: 37866
Number of extensions: 1783322
Number of successful extensions: 35351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 665
Number of HSP's successfully gapped in prelim test: 1455
Number of HSP's that attempted gapping in prelim test: 12853
Number of HSP's gapped (non-prelim): 10850
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.