Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 63252908

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
         (880 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]       1785   0.0  
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]       1736   0.0  
gi|30089954 H326 [Homo sapiens]                                       145   1e-34
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...   137   4e-32
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]   127   3e-29
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]         119   2e-26
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    68   3e-11
gi|161016767 mucin 21 [Homo sapiens]                                   59   2e-08
gi|217330641 IWS1 homolog [Homo sapiens]                               57   1e-07
gi|91982772 mucin 17 [Homo sapiens]                                    54   6e-07
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    52   2e-06
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    52   3e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    51   4e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    51   4e-06
gi|55741849 WD repeat domain 22 [Homo sapiens]                         51   5e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        50   1e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     49   2e-05
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              49   3e-05
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]      49   3e-05
gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo sa...    48   3e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    48   5e-05
gi|16554629 WD repeat domain 5 [Homo sapiens]                          47   6e-05
gi|16554627 WD repeat domain 5 [Homo sapiens]                          47   6e-05
gi|83367077 mucin 16 [Homo sapiens]                                    47   6e-05
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    47   6e-05
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    47   6e-05
gi|4557467 excision repair cross-complementing rodent repair def...    47   1e-04
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    47   1e-04
gi|23199987 WD repeat domain 5B [Homo sapiens]                         47   1e-04
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]      45   2e-04

>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
          Length = 880

 Score = 1785 bits (4624), Expect = 0.0
 Identities = 880/880 (100%), Positives = 880/880 (100%)

Query: 1   MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN 60
           MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN
Sbjct: 1   MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN 60

Query: 61  DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI 120
           DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI
Sbjct: 61  DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI 120

Query: 121 FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE 180
           FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE
Sbjct: 121 FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE 180

Query: 181 DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM 240
           DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM
Sbjct: 181 DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM 240

Query: 241 VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE 300
           VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE
Sbjct: 241 VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE 300

Query: 301 ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA 360
           ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA
Sbjct: 301 ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA 360

Query: 361 QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ 420
           QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ
Sbjct: 361 QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ 420

Query: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
           AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD
Sbjct: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480

Query: 481 NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE 540
           NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE
Sbjct: 481 NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE 540

Query: 541 SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600
           SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN
Sbjct: 541 SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600

Query: 601 SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA 660
           SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA
Sbjct: 601 SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA 660

Query: 661 HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD 720
           HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD
Sbjct: 661 HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD 720

Query: 721 TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD 780
           TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD
Sbjct: 721 TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD 780

Query: 781 NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI 840
           NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI
Sbjct: 781 NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI 840

Query: 841 TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE 880
           TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE
Sbjct: 841 TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE 880


>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
          Length = 860

 Score = 1736 bits (4496), Expect = 0.0
 Identities = 860/880 (97%), Positives = 860/880 (97%), Gaps = 20/880 (2%)

Query: 1   MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN 60
           MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN
Sbjct: 1   MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWN 60

Query: 61  DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI 120
           DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI
Sbjct: 61  DTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVI 120

Query: 121 FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE 180
           FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE
Sbjct: 121 FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE 180

Query: 181 DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM 240
           DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM
Sbjct: 181 DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGM 240

Query: 241 VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE 300
           VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE
Sbjct: 241 VARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERRE 300

Query: 301 ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA 360
           ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA
Sbjct: 301 ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVA 360

Query: 361 QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ 420
           QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ
Sbjct: 361 QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ 420

Query: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
           AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQS                    D
Sbjct: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQS--------------------D 460

Query: 481 NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE 540
           NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE
Sbjct: 461 NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE 520

Query: 541 SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600
           SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN
Sbjct: 521 SFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 580

Query: 601 SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA 660
           SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA
Sbjct: 581 SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA 640

Query: 661 HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD 720
           HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD
Sbjct: 641 HEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELD 700

Query: 721 TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD 780
           TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD
Sbjct: 701 TLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEAD 760

Query: 781 NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI 840
           NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI
Sbjct: 761 NHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTI 820

Query: 841 TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE 880
           TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE
Sbjct: 821 TVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE 860


>gi|30089954 H326 [Homo sapiens]
          Length = 597

 Score =  145 bits (367), Expect = 1e-34
 Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%)

Query: 14  VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73
           +R+R LG    +R      G R F+QR +L+  L  H GCVNT+ +N  G ++ SGSDD 
Sbjct: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215

Query: 74  KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133
           K+V+ +   R+ +    SGH++N+F AKFLP + D  +  C+ DG +    +        
Sbjct: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275

Query: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188
             +   H G ++++   P+ P TFLS GED  V   D R      K   TKE  K     
Sbjct: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330

Query: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248
             +    ++ + P   +  AVG  D  VRIYD+R +              G++ +F P H
Sbjct: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380

Query: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281
           L N   +  +T L YS DG E+L SY+ + IYLF+
Sbjct: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415



 Score =  105 bits (262), Expect = 2e-22
 Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%)

Query: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789
           YKGHRN+ T +K  NF+G  + FV+SGSDCGHIF+W++ + + +  +E D   VVNCL+P
Sbjct: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486

Query: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849
           HP  P+LA+SG+D+D+KIW+P  E+      L D +        E++ +   +  S ML 
Sbjct: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546

Query: 850 MLASLNHIRADRLEGD-RSEGSGQENENEDE 879
            L  ++H+R  R     R  G G  + + DE
Sbjct: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score =  137 bits (345), Expect = 4e-32
 Identities = 94/293 (32%), Positives = 137/293 (46%), Gaps = 32/293 (10%)

Query: 2   SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRY--LGRREFIQRLKLEATLNVHDGCVN 55
           S   + P   W V     +R LG    SR R  Y   G R F+QR +L+  L  H GCVN
Sbjct: 177 SETSALPRPRWQVVTALHQRQLG----SRPRFVYEACGARAFVQRFRLQYRLADHVGCVN 232

Query: 56  TICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCS 115
           T+ +N  G  + S  DD K+++ +   ++ +    SGH  N+F AKFLP   D  +  C+
Sbjct: 233 TVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCA 292

Query: 116 GDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR--- 172
            DG +    +   +  N       H G  +++   P+ PY FL+ GED  V   D R   
Sbjct: 293 RDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDR 352

Query: 173 --IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATG 230
              K   T+E+ K       +    ++ + P   Y  AVG  D  VRIYD+R +  +   
Sbjct: 353 PASKVVVTRENDK-------KVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKE-- 403

Query: 231 NYAGRGTTGMVARFIPSHLNNKS--CRVTSLCYSEDGQEILVSYSSDYIYLFD 281
                   G++ +F P HL N      +T + YS DG E+L SY+ D IYLF+
Sbjct: 404 ------NNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFN 450



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 40/81 (49%), Positives = 60/81 (74%), Gaps = 4/81 (4%)

Query: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789
           +KGHRN+ T +K  NF+G  + FV+SGSDCGHIF W++ + + +  L+      +NCL+P
Sbjct: 463 FKGHRNNTT-VKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEP 521

Query: 790 HPFDPILASSGIDYDIKIWSP 810
           HP+ P+LA SG+D+D+KIW+P
Sbjct: 522 HPYLPVLACSGLDHDVKIWTP 542


>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
          Length = 600

 Score =  127 bits (320), Expect = 3e-29
 Identities = 90/314 (28%), Positives = 141/314 (44%), Gaps = 29/314 (9%)

Query: 2   SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTI 57
           S   + P   W V    R+R LG    +R      G R F+QR +L+  L  H G V+TI
Sbjct: 145 SETSALPRSRWQVLTALRQRQLG--SSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTI 202

Query: 58  CWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGD 117
            +N  G  + S  DD ++++ +   +K +    SGH  N+  AKF P   D  +  C  D
Sbjct: 203 HFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHD 262

Query: 118 GVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR----- 172
           G +    +   +      +   H G  +E+   P+ PY FL+ GED  V   D R     
Sbjct: 263 GQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPA 322

Query: 173 IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNY 232
            K   T+E+ K       +    ++++ P   Y  AVG  D  VRIYD+R +  +     
Sbjct: 323 SKVVVTRENDK-------KVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKE---- 371

Query: 233 AGRGTTGMVARFIPSHL--NNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPK-DDTARE 289
                 G++ +F P HL   +    +T + YS DG E+L SY+ + IYLF+    D A+ 
Sbjct: 372 ----NNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQY 427

Query: 290 LKTPSAEERREELR 303
           +K        + ++
Sbjct: 428 VKRYKGHRNNDTIK 441



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 57/150 (38%), Positives = 86/150 (57%), Gaps = 7/150 (4%)

Query: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADN-HVVNCLQP 789
           YKGHRN+ T IK  NF+G  + FV+SGSDCGH+F W++ +++ +  +E D   +VNCL+P
Sbjct: 431 YKGHRNNDT-IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEP 489

Query: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849
           HP+ P+LA+SG+D  ++IW+P  ++      L D VI +N+   E   + +    SF  R
Sbjct: 490 HPYLPVLATSGLDQHVRIWTPTAKTATELTGLKD-VIKKNK--QERDEDNLNYTDSFDNR 546

Query: 850 MLASLNHIRADRLEGDRSEGSGQENENEDE 879
           ML         R         G E  +E+E
Sbjct: 547 MLRFFVRHLLQRAHQPGWRDHGAEFPDEEE 576


>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
          Length = 676

 Score =  119 bits (297), Expect = 2e-26
 Identities = 89/293 (30%), Positives = 134/293 (45%), Gaps = 29/293 (9%)

Query: 13  DVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDD 72
           D+ +R +          RY     FI+RL LEA L  H GCVN + WN+ G+ + SGSDD
Sbjct: 9   DLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDD 68

Query: 73  TKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETN 132
              ++ +P   K L ++ +GH ANIFS KFLP   D+ +++ + D  +   ++      +
Sbjct: 69  QHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHDLTVKETIH 128

Query: 133 RQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDILINCRR 192
               F  H      I T P  P TF S  EDG +R +D  ++ +    +   D+   C +
Sbjct: 129 ---MFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYD--LRENSKHSEVLIDLTEYCGQ 183

Query: 193 --AATSVAICPPIPYYLAVGCSDSSVRIYDRRML----GTRATGNYAGRGT--------- 237
              A  + + P     LAVG S   VR+YD RM+     +      AG  T         
Sbjct: 184 LVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLP 243

Query: 238 TGMVARFIPSHL------NNKSCRV---TSLCYSEDGQEILVSYSSDYIYLFD 281
            G    ++  HL       N   RV   T + +S +G E+LV+   + +YLFD
Sbjct: 244 DGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFD 296



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 52/150 (34%), Positives = 86/150 (57%), Gaps = 12/150 (8%)

Query: 733 YKGHRNSRTMIKEANFWGAN--FVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 790
           Y GH N+ T IKEANF+G+N  +++SGSD G  FIW++ T   + +L+ D  +VNCLQPH
Sbjct: 529 YCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPH 588

Query: 791 PFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLRM 850
           P    LA+SGID  +++W+P  ES     ++ +++   ++       N   + A  +  M
Sbjct: 589 PSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDMEGASQ------ANQRRMNADPLEVM 642

Query: 851 LASLNHIRADRLEGDRSEGSGQENENEDEE 880
           L ++ +    R+ G  S G+G  ++ +  E
Sbjct: 643 LLNMGY----RITGLSSGGAGASDDEDSSE 668


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 71/367 (19%), Positives = 136/367 (37%), Gaps = 2/367 (0%)

Query: 315  DWSDTGPRARPESERERDGEQSPNVSLMQRMSDML-SRWFEEASEVAQSNRGRGRSRPRG 373
            D SD+    R +S    D   S + S     SD   S     +S+ + S+          
Sbjct: 849  DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908

Query: 374  GTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHS 433
              S     +  +  SS     S+ +   D+        S+ S+ S+ + ++S  + S  S
Sbjct: 909  SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968

Query: 434  TPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTG 493
            +   SS  S+   S ++S       S   S   N    S S D    +N+   S    + 
Sbjct: 969  SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028

Query: 494  EPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEG 553
                S   S    ++ +   + + + S+ + SS    S   S+  + S    SS      
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 554  DSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSC 613
            DS   +    S D +   +   + +  ++  +   SD   +     +S   N  +   S 
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148

Query: 614  GVPEESASSEKAKEPETSDQT-STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQ 672
               + S SS+ +   ++SD + S++S+ + N+++      +  +  S+    S+  S   
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208

Query: 673  DTDDSDD 679
            D+ DS D
Sbjct: 1209 DSSDSSD 1215



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 77/365 (21%), Positives = 143/365 (39%), Gaps = 22/365 (6%)

Query: 330 ERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSS 389
           + D   S N S     SD         S  ++S+  +  S      S+SD S   +  SS
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651

Query: 390 PDLEVSETAMEV---DTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQ 446
            + + S+++      D+        S+SS+ S+ +  +S  ++S +S+    S DS    
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 447 SVEASGHHTHHQSDSPSS-------VVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSL 499
           S ++S     + SDS SS         N    S S D    +++   S    + +   S 
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 500 HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQE-----ESFVPQSSVQPPEGD 554
             S    ++++   N +   S  + SS    S   S+  +     +S    SS      D
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 555 SETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCG 614
           S   +    S D +   +G  +++   N  + + S   +     SNS + +D     S  
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDS--SNRSDSSNSSDSSDSSDSSNSSDSSD-----SSD 884

Query: 615 VPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDT 674
             E S SS+ +    +SD  S++S+ + ++++      +  +  S+    S+  S   D+
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 675 DDSDD 679
            DS D
Sbjct: 945 SDSSD 949



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 71/366 (19%), Positives = 138/366 (37%), Gaps = 12/366 (3%)

Query: 326  ESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPT 385
            +S    +   S N S     SD        +S+ + S+     S     +  SD S    
Sbjct: 793  DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852

Query: 386  VPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQR 445
              SS   + S ++   D+        S+ S+ S ++ ++S  ++S +S+   SS  S   
Sbjct: 853  SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912

Query: 446  QSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEG 505
             S ++S      +S + S   N    S S D    +++   S    + +   S   S   
Sbjct: 913  DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972

Query: 506  TTTSTIKLNFTD-----------EWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGD 554
            ++ S+   N +D           + S  ++SS    S   S+    S    SS      D
Sbjct: 973  SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032

Query: 555  SETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCG 614
            S   +    S D +   +   + N  ++  +   SD   +     +S      +   S  
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092

Query: 615  VPEESASSEKAKEPETSDQT-STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQD 673
              + S SS+ +   ++SD + S++S+ + N+++      +  +  S++   S+  S   D
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152

Query: 674  TDDSDD 679
            + DS D
Sbjct: 1153 SSDSSD 1158



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 69/367 (18%), Positives = 146/367 (39%), Gaps = 6/367 (1%)

Query: 315  DWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGG 374
            D SD+      +S    D   S N S     SD       ++S  + S+     S     
Sbjct: 814  DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 375  TSQSDIS-TLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHS 433
            ++ SD S +  +  SS   + S+++   D+ +      S++S+ S+ + ++S  +ES +S
Sbjct: 874  SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD----SSNSSDSSDSSNSSDSSESSNS 929

Query: 434  TPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTG 493
            +   +S DS        S   ++    S SS  +    S   +    +++   S    + 
Sbjct: 930  SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989

Query: 494  EPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEG 553
            +   S   S    ++ +   + + + S+ + SS    S   S+  + S    SS      
Sbjct: 990  DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049

Query: 554  DSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSC 613
            DS   +    S D +   +   + +  ++  +   SD   +     +S   +  +   S 
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109

Query: 614  GVPEESASSEKAKEPETSDQT-STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQ 672
               + S SS+ +   ++SD + S++S+ + N+++     ++  +  S+    S+  S   
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169

Query: 673  DTDDSDD 679
            D+ DS D
Sbjct: 1170 DSSDSSD 1176



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 68/363 (18%), Positives = 144/363 (39%), Gaps = 14/363 (3%)

Query: 317 SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTS 376
           S  G  +    E + +G  S +       SD  S      S    +N      +   G  
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545

Query: 377 QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPL 436
           +SD S   +  SS   + S+++             S SS  ++ + S SS ++S  S+  
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSS------------DSDSSDSNSSSDSDSSDSDSSDSSDS 593

Query: 437 LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPV 496
            SS  S    S ++S   +   SDS  S  +K   S S  +  D++++  S    + +  
Sbjct: 594 DSSDSSNSSDSSDSSD--SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651

Query: 497 LSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSE 556
            +   S    ++++   + + + S  +SSS    S   S+  + S   +SS      DS+
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 557 TKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVP 616
           +    +SS   +   +  ++ +  ++  +   SD   +     +S   +  N   S    
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 617 EESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDD 676
           + S SS+ +   +++D +++  +++ +N++        +    + +  S+  S   ++ D
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 677 SDD 679
           S D
Sbjct: 832 SSD 834



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 65/355 (18%), Positives = 134/355 (37%), Gaps = 3/355 (0%)

Query: 326  ESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPT 385
            +S    D  +S N S     SD  +    ++S+ + S+     S     ++ SD S   +
Sbjct: 916  DSSNSSDSSESSNSSDNSNSSDSSNS--SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 386  VPSSPDLEVSETAMEVDTP-AEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQ 444
              SS     S+++   D+  +      S SS  S  + S+ S   S  S    SS  S+ 
Sbjct: 974  SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033

Query: 445  RQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE 504
              S ++S       S   S   N    S S D    +++   S    + E   S   S  
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093

Query: 505  GTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESS 564
              ++ +   + + + S  + SS    S   S+  + S    SS      DS   +    S
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153

Query: 565  EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEK 624
             D +   +   + +  ++  +   S+   +     +S   +  +   S    + S SS+ 
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213

Query: 625  AKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
            +   ++SD + +  +++ N ++        +   ++ + + + DS+   +D +D+
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 76/366 (20%), Positives = 138/366 (37%), Gaps = 14/366 (3%)

Query: 315 DWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGG 374
           D SD+       S+ E D   S + S     SD  S    + S+ + S+     S     
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKS---DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671

Query: 375 TSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHS 433
           +  SD S+     +S D  + S+++   ++        S SS  S  ++S SS ++S +S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731

Query: 434 TPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTG 493
           +    S +S        S + +     S SS  +    S    +  D++N   S      
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791

Query: 494 EPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEG 553
                   S++ + +S    +     S  ++SS    S   S+    S    SS      
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851

Query: 554 DSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSC 613
           DS++    +SS          S  +   +  N + S   +     SNS + +D +     
Sbjct: 852 DSDSSNRSDSSNS--------SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903

Query: 614 GVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQD 673
              + S SS+ +    +SD  S+ES+ + +N+N      +  +  S+    S+  S   D
Sbjct: 904 DSSDSSNSSDSSDSSNSSD--SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 674 TDDSDD 679
           + +S D
Sbjct: 962 SSNSSD 967



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 69/357 (19%), Positives = 136/357 (38%), Gaps = 11/357 (3%)

Query: 327  SERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTV 386
            S    D   S N S     SD  S    ++S  + SN     S     ++ SD S     
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSD--SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809

Query: 387  PSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQ 446
              S D   S+++   D+        S++S+ S+ +  +S  ++S  S    SS  S+   
Sbjct: 810  SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869

Query: 447  SVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGT 506
            S ++S     + SDS  S  + +  + S      N+++  S              S++ +
Sbjct: 870  SSDSS-----NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 507  TTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSED 566
             +S    N     SS +S S        S     S    +S    + +S   +   +S D
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 567  VTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAK 626
             +   +   + +  ++  +   SD   +    ++S   N  +   S    + S SS+ + 
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044

Query: 627  EPETSDQT----STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
              ++SD +    S++S+ + ++++      +  +  S+    S+  S   D+ DS D
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 74/356 (20%), Positives = 143/356 (40%), Gaps = 34/356 (9%)

Query: 326  ESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDIS-TLP 384
            +S    D   S N S     SD  +    ++S+ + S+     S     +  SD S +  
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNS--SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784

Query: 385  TVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQ 444
            +  SS   + S+++   D+        S+ S+ S  ++S+ S   S  S    SS  S+ 
Sbjct: 785  SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844

Query: 445  RQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE 504
              S + S   + ++SDS +S       S S D    +N+   S    + E        + 
Sbjct: 845  SDSSDGSDSDSSNRSDSSNS-------SDSSDSSDSSNSSDSSDSSDSNE--------SS 889

Query: 505  GTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESS 564
             ++ S+   N +D  SS +S+S        S+  + S    SS      D+   +   +S
Sbjct: 890  NSSDSSDSSNSSDSDSSDSSNS--------SDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 565  EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDL-NLDRSCGVPEESASSE 623
             D +   +  ++ +   +  +   SD       DSNS + +D  N   S    + S SS+
Sbjct: 942  SDSSDSSDSSNSSDSSNSSDSSNSSDSS-----DSNSSDSSDSSNSSDSSDSSDSSDSSD 996

Query: 624  KAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
             +    +SD + +  +++ +N++        +    + + + + DS+  D+ DS D
Sbjct: 997  SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS--DSSDSSD 1050



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 62/323 (19%), Positives = 125/323 (38%), Gaps = 12/323 (3%)

Query: 361 QSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQ 420
           +S+ G+G+S      S SD S       S D + S++    D+ +       + S+ S+ 
Sbjct: 539 KSDSGKGKSDSSDSDS-SDSSNSSDSSDSSDSDSSDSNSSSDSDSSD-----SDSSDSSD 592

Query: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
           + S+ S   S  S    SS  S+   S ++    +  +SDS  S         +  +  D
Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652

Query: 481 NNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEE 540
           N++   S              S++ +++S    N +D   S  SS+    S        +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSD-SSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 541 SFVPQSSVQPPEGDSETKAPEESSE-----DVTKYQEGVSAENPVENHINITQSDKFTAK 595
           S     S      DS++    +SS+     D +   +  ++ +  ++  +   SD   + 
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 596 PLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEA 655
               +S   N  + + S    + S SS  +    +SD + +  +++ +++N      +  
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 656 TGPSAHEETSTRDSALQDTDDSD 678
           +  S++   S+  S   D  DSD
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSD 854



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 72/360 (20%), Positives = 148/360 (41%), Gaps = 11/360 (3%)

Query: 327  SERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDIST---- 382
            S    D   S N S     SD       ++S+ + SN     S     +S S  S+    
Sbjct: 686  SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745

Query: 383  -LPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLL-SSP 440
               +  SS   + S+++   D+        S+ S+ S+ ++ +S+ ++S  S+    SS 
Sbjct: 746  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 441  DSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLH 500
             S+   S ++S   + + SDS +S  +    S S D    +++   S    +     S  
Sbjct: 806  SSDSSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 501  YSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAP 560
              +  ++ S+   + +D   S  SS+    S   +    +S    +S    +  + + + 
Sbjct: 865  SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 561  EES-SEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEES 619
            E S S D +   +  ++ +  ++  +   SD   +    SNS + +D N   S      S
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD-SSNSSDSSDSNSSDSSDSSNSS 983

Query: 620  ASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
             SS+ +   ++SD  S++S+ + ++++      +  +  S++   S+  S   D+ DS D
Sbjct: 984  DSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 63/364 (17%), Positives = 138/364 (37%), Gaps = 8/364 (2%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTS 376
            SD+   +        D   S + S     SD       E+S  + ++     S     + 
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS-----SESSNSSDNSNSSDSSNSSDSSD 946

Query: 377  QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPL 436
             SD S      +S D   S  + + ++        S+ S+ S+ +  +S  ++S +S+  
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006

Query: 437  LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM-SLDEQQDNNNEKLSPKPGTGEP 495
              S DS    +   S + +   + S SS  +    S  S D    +++   S    + + 
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066

Query: 496  VLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDS 555
              S   S    ++ + + + + + S+ + SS    S   S+  + S    SS      DS
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126

Query: 556  ETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGV 615
               +    S D +   +   +    ++  +   SD   +     +S   +  N   S   
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186

Query: 616  PEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTD 675
             + S SS+ +   ++SD + +  +++ ++++        +    ++E + + DS+  D+ 
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS--DSS 1244

Query: 676  DSDD 679
            DS +
Sbjct: 1245 DSSN 1248



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 61/356 (17%), Positives = 134/356 (37%), Gaps = 2/356 (0%)

Query: 326  ESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPT 385
            +S    +   S + S     SD  S     +S+ + S+     S     +  S+ S    
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940

Query: 386  VPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDS-EQ 444
               S D   S  + +    ++      +S + S+ +  +S+ ++S  S+    S DS + 
Sbjct: 941  SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 445  RQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE 504
              S ++S       S + S   N    S S D    +++   S    + +   S + S  
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060

Query: 505  GTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESS 564
              ++ +   + + + S  + SS    S   S   + S    SS      DS   +    S
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120

Query: 565  EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEK 624
             + +   +   + +  ++  +   SD   +     +S   +  +   S    + S SS  
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 625  AKEPETSDQT-STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
            +   ++SD + S++S+ + ++++      +  +  S+    S+  S   D+++S D
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 72/365 (19%), Positives = 140/365 (38%), Gaps = 25/365 (6%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTS 376
            SD+   +        D   S N S     SD  S    ++S+ + S+     S     ++
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD--SSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 377  QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPL 436
             SD S   +  SS   + S+++   D+        S+ S+ S+ +  +S  ++S  S+  
Sbjct: 1018 SSDSSN--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075

Query: 437  LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPV 496
              S DS +      S + +     S SS  +    S    +  D++N   S         
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135

Query: 497  LSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDS- 555
                 S++ + +S        E S  + SS    S   S+  + S    SS      DS 
Sbjct: 1136 SDSSNSSDSSDSS--------ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187

Query: 556  ETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGV 615
            ++    +SS+         S+++          SD   +     +S   +  + + S   
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDS----------SDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 616  PEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTD 675
             + S SS+ +   ++SD  S++S+ + +++N E   Q+++   + +   S  DS   D++
Sbjct: 1238 SDSSDSSDSSNSSDSSD--SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295

Query: 676  DSDDD 680
             S  D
Sbjct: 1296 HSTSD 1300



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 78/444 (17%), Positives = 173/444 (38%), Gaps = 49/444 (11%)

Query: 263 EDGQEILVSYSSDYIYLFDP--KDDTAREL---KTPSAEERREELRQPPVKRLRLRGDWS 317
           ED  +  +  +SD    +DP  K+D   E+   KT  +EE    + +             
Sbjct: 288 EDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPE------------- 334

Query: 318 DTGPRARPESER--ERDGEQSPNVSLMQRMSDMLSRWFEEASEV---AQSNRGRGRSRPR 372
           D G +   ++++   R+ ++  N    +  +  + +  ++  E+   +  NR   +   +
Sbjct: 335 DNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGK 394

Query: 373 GGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPH 432
           G   + D      +    +++     + ++ P ++  +P      S     ++S     +
Sbjct: 395 GNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKS-EPGNKVGHSNTGSDSNSDGYDSY 453

Query: 433 STPLLSSPDSEQRQSVEASGHH-THHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPG 491
                S    +   S E++G+   + +SD+ SS  ++   S + DE +DN N   S   G
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDANSESDNNSS--SRGDASYNSDESKDNGNG--SDSKG 509

Query: 492 TGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPP 551
             +        T  + ++    N  D+ +  + S +G      S+  + S    SS    
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDD-NDKSDSGKGKSDSSDSDSSDSS---NSSDSSD 565

Query: 552 EGDSETKAPEESSE-DVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLD 610
             DS++     SS+ D +      S+++   +  N + S   +     S+S + +D   D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625

Query: 611 RSCGVPE-----------ESASSEKAKEPETSDQT----STESATNENNTNPEPQFQTEA 655
            S    +           +S SS+ +   ++SD +    S++S+ + ++++      +  
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 656 TGPSAHEETSTRDSALQDTDDSDD 679
           +  S+    S+  S   D+ DS D
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSD 709



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 33/163 (20%), Positives = 65/163 (39%), Gaps = 16/163 (9%)

Query: 524 SSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENH 583
           SSSRG  S+   E ++             G     A ++ S+  +      S  N    +
Sbjct: 485 SSSRGDASYNSDESKDNG----------NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN 534

Query: 584 INITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEE------SASSEKAKEPETSDQTSTE 637
            +  +SD    K   S+S   +  N   S    +       S+S   + + ++SD + ++
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594

Query: 638 SATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDD 680
           S+ + N+++      +  +  S+    S  DS+  ++D SD D
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 74/323 (22%), Positives = 118/323 (36%), Gaps = 24/323 (7%)

Query: 369 SRPRGGTS---QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTS 425
           S P  G S    SD ST  +  S+     S T     + A      +TSS  S   +S S
Sbjct: 126 STPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSES 185

Query: 426 SPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEK 485
           S   S  ST   S   +    +  A+   +   S+   +  N +  + S       N+E 
Sbjct: 186 STVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSES 245

Query: 486 LSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQ 545
            +P  G G        ++E +TTS+     T+  SS  SS  GI +   SE    S    
Sbjct: 246 STPSSGAGTAT-----NSESSTTSSGAGTATNSESSTVSS--GISTVTNSESSTPSSGAN 298

Query: 546 SSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDS------ 599
           ++       + + A   ++ D +    G S     E+  + T S   TA   +S      
Sbjct: 299 TATNSESSTTSSGANTATNSDSSTTSSGASTATNSES--STTSSGASTATNSESSTTSSG 356

Query: 600 -----NSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTE 654
                NSG  +  +   S     ES++        T+ ++ST S+     TN E    + 
Sbjct: 357 ASTATNSGS-STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSS 415

Query: 655 ATGPSAHEETSTRDSALQDTDDS 677
               + + E+ST  S      +S
Sbjct: 416 GASTATNSESSTTSSGANTATNS 438



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 67/317 (21%), Positives = 114/317 (35%), Gaps = 24/317 (7%)

Query: 375 TSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHST 434
           T+ S  ST     SS     + TA   D+        +TSS  S   +S SS T S  ST
Sbjct: 112 TTSSGASTATNSESSTPSSGASTATNSDSS-------TTSSGASTATNSDSSTTSSEAST 164

Query: 435 PLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGE 494
              S   +    +  A+   +   S   S+  N +  + S       N+E  +   G G 
Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224

Query: 495 PVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE---------GQEESFVPQ 545
                  ++E +TTS+     T+  SS  SS  G  ++ +S             ES    
Sbjct: 225 AT-----NSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVS 279

Query: 546 SSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERN 605
           S +     +SE+  P   +   T  +   ++     N    + S   ++    + + E +
Sbjct: 280 SGISTVT-NSESSTPSSGANTATNSESSTTSSG--ANTATNSDSSTTSSGASTATNSESS 336

Query: 606 DLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETS 665
             +   S     ES+++       T+  +ST S+     TN E    +     +   E+S
Sbjct: 337 TTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESS 396

Query: 666 TRDSALQDTDDSDDDPV 682
           T  S      +S+   V
Sbjct: 397 TTSSGASTATNSESSTV 413



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 47/202 (23%), Positives = 75/202 (37%), Gaps = 21/202 (10%)

Query: 496 VLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDS 555
           +L L  +T    TST     +   SS AS++   GS   S G   + +  SSV       
Sbjct: 15  LLHLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSI 74

Query: 556 ETKA---------PEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDS---NSGE 603
            T +            ++ + +    G+S     E+  + T S   TA   +S   +SG 
Sbjct: 75  VTNSEFHTTSSGISTATNSEFSTVSSGISIATNSES--STTSSGASTATNSESSTPSSGA 132

Query: 604 RNDLNLD---RSCGVPEESASSEKAKEPETSDQTSTESATNENN----TNPEPQFQTEAT 656
               N D    S G    + S       E S  T++ES+T  +     TN E    +   
Sbjct: 133 STATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRA 192

Query: 657 GPSAHEETSTRDSALQDTDDSD 678
             + + E+ST  S      +S+
Sbjct: 193 STATNSESSTTSSGASTATNSE 214


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 80/371 (21%), Positives = 135/371 (36%), Gaps = 51/371 (13%)

Query: 314 GDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRG 373
           GD SD G     + ER+   +   +V+     SD  S   E  SE   S+R  G  +   
Sbjct: 8   GDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGS--VERHSENETSDREDGLPKGHH 65

Query: 374 GTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHS 433
            T   +   L    S  + E      + D+ +E+  +P  S + +   +   S +ES  +
Sbjct: 66  VTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEET 125

Query: 434 TPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTG 493
             L  S DSE  + +        H SDS +  V K   S       D+  E+L   P   
Sbjct: 126 RKLPGS-DSENEELLNG------HASDSENEDVGKHPAS-------DSEIEELQKSP--- 168

Query: 494 EPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEG 553
                   +++  T   +K   +D      S S     H  S+ + E        +PP+ 
Sbjct: 169 --------ASDSETEDALKPQISD------SESEEPPRHQASDSENE--------EPPK- 205

Query: 554 DSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSC 613
               +  +  SE++ K Q   S       H      ++   KP  S+S E  D    ++ 
Sbjct: 206 ---PRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDS-ESEDPPRHQAS 261

Query: 614 GVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEAT-----GPSAHEETSTRD 668
               E     +  + E+ D    +++ +EN   P+P+     +     GP++  ET    
Sbjct: 262 DSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDAS 321

Query: 669 SALQDTDDSDD 679
              Q  +  DD
Sbjct: 322 RHKQKPESDDD 332



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 68/315 (21%), Positives = 117/315 (37%), Gaps = 62/315 (19%)

Query: 410 QPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHH-THHQSDSPSSVVNK 468
           Q S S T S + HS +  ++     P                GHH T  ++D P ++   
Sbjct: 36  QHSGSDTGSVERHSENETSDREDGLP---------------KGHHVTDSENDEPLNLNAS 80

Query: 469 QLGSMSLDEQQDNNN---EKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWS----- 520
              S  L  Q+D+++   E+  P     E      + ++  +  T KL  +D  +     
Sbjct: 81  DSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLN 140

Query: 521 --SIASSSRGIGSHCKSEGQ--------------EESFVPQ----SSVQPPE---GDSET 557
             +  S +  +G H  S+ +              E++  PQ     S +PP     DSE 
Sbjct: 141 GHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSEN 200

Query: 558 KAP------EESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDR 611
           + P      +  SE++ K Q   S       H      ++   KP  S+S E  D    +
Sbjct: 201 EEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDS-ESEDPPRHQ 259

Query: 612 SCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQF-QTEATGP-------SAHEE 663
           +     E     +  + E+ D    +++ +EN   P+P+   +E+ GP       S  E+
Sbjct: 260 ASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETED 319

Query: 664 TSTRDSALQDTDDSD 678
            S      +  DDSD
Sbjct: 320 ASRHKQKPESDDDSD 334



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 78/405 (19%), Positives = 142/405 (35%), Gaps = 66/405 (16%)

Query: 284 DDTAREL-KTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLM 342
           D  + EL +   ++   EE  +PP        D +  G  +  E  R+  G  S N  L+
Sbjct: 81  DSESEELHRQKDSDSESEERAEPPASDSE-NEDVNQHGSDSESEETRKLPGSDSENEELL 139

Query: 343 QRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVD 402
                        AS+    + G+  +      S S+I  L   P+S            D
Sbjct: 140 NG----------HASDSENEDVGKHPA------SDSEIEELQKSPAS------------D 171

Query: 403 TPAEQFLQPSTSSTMSAQA--HSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD 460
           +  E  L+P  S + S +   H  S         P +S  +SE+    + S      +S+
Sbjct: 172 SETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDS----ESE 227

Query: 461 SPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLS---LHYSTEGTTTSTIKLNFTD 517
            P              +  D+ NE+L PKP   +        H +++       K   +D
Sbjct: 228 EPPR-----------HQASDSENEEL-PKPRISDSESEDPPRHQASDSENEELPKPRISD 275

Query: 518 EWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAE 577
             S     ++   S       EE   P+ S    EG  +  A +  +ED +++++   ++
Sbjct: 276 SESEDPPRNQASDSE-----NEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESD 330

Query: 578 NPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTE 637
           +  +       ++         N    +D ++DR      +S   E  K+   SD+   E
Sbjct: 331 DDSDRENKGEDTEM-------QNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKE 383

Query: 638 SATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPV 682
               E     + +    +      + ++ +   + D DDSD D V
Sbjct: 384 G---EEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAV 425



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 56/288 (19%), Positives = 101/288 (35%), Gaps = 22/288 (7%)

Query: 294 SAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWF 353
           +++   EEL +P +       D     P     S+ E +    P +S  +      ++  
Sbjct: 234 ASDSENEELPKPRIS------DSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQAS 287

Query: 354 EEASE------VAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQ 407
           +  +E      V+ S     +  P   +   D S     P S D    E   E DT  + 
Sbjct: 288 DSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGE-DTEMQN 346

Query: 408 FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN 467
               S S     + HS+ S  E      + S  D ++ +  + +       SDS      
Sbjct: 347 DSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKA 406

Query: 468 KQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE-GTTTSTIKLNFTDEWSSIASSS 526
               S  + +  D++++ +S K G  E  ++     E G   S  K    D + S + S 
Sbjct: 407 SAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESG 466

Query: 527 RG--------IGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSED 566
                      G     E +E +   Q  ++  +G+++ K  E+S  D
Sbjct: 467 NEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSD 514


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 79/352 (22%), Positives = 136/352 (38%), Gaps = 32/352 (9%)

Query: 356  ASEVAQSNRGRGRSRPRGGTSQSDISTLPTVP-SSPDLEVSETAMEVDTPAEQFLQPSTS 414
            ++E   S    G S P    S+  ++ L +VP S+  +  SE ++   TP +     +TS
Sbjct: 3198 STEATSSTTAEGTSIPTSTPSEG-MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256

Query: 415  STMSAQ---AHSTSSPTESPH--STPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQ 469
            +  S+    A  TS PT +P   STPL S P S    +   +   +   +D+ + V    
Sbjct: 3257 TEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYS 3316

Query: 470  LGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE---GTTTSTIKLNFTDEWSSIASSS 526
              S S     D  +   S       P+ ++ +ST     +  ST+     D  + + +S+
Sbjct: 3317 QASSS-PPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST 3375

Query: 527  RGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINI 586
                S   +EG     +P SS  P EG +   +   S+  V   +    +  PV+++  +
Sbjct: 3376 EASLSPTTAEGTS---IPTSS--PSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLV 3430

Query: 587  TQSDKFTAKP-------LDSNSGERNDLNLD----RSCGVPEESASSEKAKEPETSDQTS 635
            T S + ++ P       L +++       L      +  V    AS+      +TS   +
Sbjct: 3431 TTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT 3490

Query: 636  TESATNENNTNPEPQFQTEATG-----PSAHEETSTRDSALQDTDDSDDDPV 682
            T S TN + T  E      +T      P  +   ST   A  +       PV
Sbjct: 3491 TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPV 3542



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 80/322 (24%), Positives = 123/322 (38%), Gaps = 34/322 (10%)

Query: 380  ISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHS--TPLL 437
            +ST+  V SS D  +S T ++  TP    +  ST +T S  A  TS PT +P    TPL 
Sbjct: 3171 VSTMLVV-SSEDSTLSATPVDTSTP----VTTSTEATSSTTAEGTSIPTSTPSEGMTPLT 3225

Query: 438  SSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVL 497
            S P S    +   +   +    DS + +      S S    +  +    +P  G+  P+ 
Sbjct: 3226 SVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGS-TPLT 3284

Query: 498  SLHYST---EGTTTSTIKLNFTDEWSSI-----ASSSRGI--GSHCKSEGQEESFVPQSS 547
            S+  ST     + TST+     D  + +     ASSS  I  G+   +    E   P ++
Sbjct: 3285 SMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTN 3344

Query: 548  -------VQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600
                   V   E  + +  P ++S  VT   E   +    E     T S      PL S 
Sbjct: 3345 MSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASM 3404

Query: 601  --------SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQ 652
                    S E N L+          + S+E +  P  ++ TS  ++T    + P     
Sbjct: 3405 PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTP-LSIM 3463

Query: 653  TEATGPSAHEETSTRDSALQDT 674
              +T P A  E ST  +   DT
Sbjct: 3464 PLSTTPVASSEASTLSTTPVDT 3485



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 80/348 (22%), Positives = 130/348 (37%), Gaps = 38/348 (10%)

Query: 360 AQSNRGRGRSRP------RGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPST 413
           + S    G S P      RG T  S   +   V SS    +S T ++ +TP     + ++
Sbjct: 609 SSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATS 668

Query: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM 473
           SST +A+  S  + T +  STPL S P +    +   +   +    D+ + V      S 
Sbjct: 669 SST-TAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASS 727

Query: 474 SLDEQQDNNNEKLSPKPG----TGEPV-LSLHYSTEGTTTSTIKLNFTDEWSSIASSSRG 528
           S       +    +P  G    T  PV  +L  S+E +T ST  L   D  + I +S+  
Sbjct: 728 SPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL---DTSTHITTSTEA 784

Query: 529 IGSHCKSEGQEESFVPQSSVQP--------------PEGDSETKAPEESSEDVTKYQEGV 574
             S   +EG        S   P              PE  + +  P +S+  VT   E  
Sbjct: 785 SCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVS 844

Query: 575 SAENPVENHINITQS-----DKFTAKPLDSNSGERNDLNLDRSCGVPEESA---SSEKAK 626
           S+  P E     T +        T+ P+ +     + ++   +  V   +    S+E   
Sbjct: 845 SSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARS 904

Query: 627 EPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDT 674
            P TS+ TS  ++T    + P      ++T P    E  T  +   DT
Sbjct: 905 SPTTSEGTSMPTSTPGEGSTPLTS-MPDSTTPVVSSEARTLSATPVDT 951



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 71/314 (22%), Positives = 122/314 (38%), Gaps = 34/314 (10%)

Query: 376  SQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQ----PSTSSTMSAQAHSTSSPTESP 431
            S S + T   V SSP      T++ + TP+E        P +++T+++   ++ S T + 
Sbjct: 1482 SNSPVVTSTAVSSSPT-PAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAV 1540

Query: 432  HSTPLLS-SPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKP 490
             STP+ + S  S    + + +   T   S+  + + +  + +M +   + N    LS  P
Sbjct: 1541 TSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANT---LSTTP 1597

Query: 491  GTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSS--V 548
                    +   T+ T ++    + T E SS+  S+   GS   +       +P S+  V
Sbjct: 1598 --------IDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTS------IPVSTTPV 1643

Query: 549  QPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDS--------N 600
              PE  + +  P +S+  V    E  S+  P E     T +      PL S         
Sbjct: 1644 ASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVA 1703

Query: 601  SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSA 660
            S   + L+          + S+E    P TS+ TS  ++T    T P        T P  
Sbjct: 1704 SSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTT-PVL 1762

Query: 661  HEETSTRDSALQDT 674
              E ST  +   DT
Sbjct: 1763 SSEASTLSATPIDT 1776



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 73/321 (22%), Positives = 114/321 (35%), Gaps = 30/321 (9%)

Query: 367  GRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTS- 425
            G S P    S+   + L ++P S  L VS  A  + T       P+T+ST  + + +T+ 
Sbjct: 1972 GTSMPTPAYSEGS-TPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAG 2030

Query: 426  -----SPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
                 + T S  +TPL   P S            +    DS + V N    S S   +  
Sbjct: 2031 GTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAE-- 2088

Query: 481  NNNEKLSPKPGTGEPVL-SLHYSTEGTTT---STIKLNFTDEWSSIASSSRGIGSHCKSE 536
              +      P  G P+L S+  ST    +   ST+     D  S + +S+    S   +E
Sbjct: 2089 -GSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTE 2147

Query: 537  GQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKP 596
            G       Q+S         T  P  S+  V        +  PV+    +T S +  + P
Sbjct: 2148 GTS----MQTSTYSDRRTPLTSMP-VSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSP 2202

Query: 597  LDSNSGERNDLNLDRSCGVPEESA----SSEKAKEPETSDQTSTESATNENNTNPEPQFQ 652
              S                P E +    S   +  P  + + ST SAT  + + P     
Sbjct: 2203 TTSE-------GTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST 2255

Query: 653  TEATGPSAHEETSTRDSALQD 673
               + P+  E TS   S L +
Sbjct: 2256 EATSSPTTAEGTSIPTSTLSE 2276



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/317 (21%), Positives = 115/317 (36%), Gaps = 59/317 (18%)

Query: 368  RSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSP 427
            R  P   +  S +ST P   S+P    +ET+    T     L  ST+S        ++  
Sbjct: 1227 RHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTS------EGSTLL 1280

Query: 428  TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLS 487
            T  P ST L++SP++    +            D+   VV              +N    S
Sbjct: 1281 TSIPVSTTLVTSPEASTLLTTPV---------DTKGPVVT-------------SNEVSSS 1318

Query: 488  PKPGTGEPVLSLHYSTEGTTTSTIKLNFT---------------DEWSSIASSSRGIGSH 532
            P P  G  + +  YS   T  ++I +N T               D  + + +S+    S 
Sbjct: 1319 PTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSP 1378

Query: 533  CKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKF 592
              SEG   + +P S+  P EG +   +   S+  V   +    +  PV+     T S + 
Sbjct: 1379 TTSEG---TSMPNSN--PSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433

Query: 593  TAKPLDSNSGERNDLNLDRSCGVPEESASSEK----AKEPETSDQTSTESATNENNTNPE 648
            T+ P  +         +      P E  +  K    +  P  + + ST S T  ++ +P 
Sbjct: 1434 TSSPTTAE-------GISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486

Query: 649  PQFQTEATGPSAHEETS 665
                  ++ P+  E TS
Sbjct: 1487 VTSTAVSSSPTPAEGTS 1503



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 75/339 (22%), Positives = 123/339 (36%), Gaps = 34/339 (10%)

Query: 367  GRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSS 426
            G S P    S+   + L ++P S  L  S  A  + T         T+ST ++ + +T+ 
Sbjct: 734  GASMPTSTPSEGS-TPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTE 792

Query: 427  PTESPHSTPL---------------LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLG 471
             T  P STP                ++SP++    +     +     S   SS      G
Sbjct: 793  GTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEG 852

Query: 472  SMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTT---TSTIKLNFTDEWSSIASSSRG 528
            +             L+  P +   V +   ST  TT   TST   N T+  SS  ++S G
Sbjct: 853  TSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSS-PTTSEG 911

Query: 529  IGSHCKSEGQEE---SFVPQSSVQPPEGDSET--KAPEESSEDVTKYQEGVSAENPVENH 583
                  + G+     + +P S+      ++ T    P ++S  VT   E  S+    E  
Sbjct: 912  TSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGT 971

Query: 584  INITQSDKFTAKPLDSN--------SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTS 635
               T +      PL S         + E + L+          + S+E +  P T++ TS
Sbjct: 972  SIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTS 1031

Query: 636  TESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDT 674
              ++T    + P  +     T   A  ETST  +   DT
Sbjct: 1032 MPTSTPSEGSTPLTRMPVSTT-MVASSETSTLSTTPADT 1069



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 71/335 (21%), Positives = 123/335 (36%), Gaps = 56/335 (16%)

Query: 380  ISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSS 439
            +ST+P V S     +S T ++  TP     + +TSS  +A+  S  + T S  +TPL S 
Sbjct: 2227 VSTMPVVTSEAST-LSATPVDTSTPVTTSTE-ATSSPTTAEGTSIPTSTLSEGTTPLTSI 2284

Query: 440  PDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDN-----NNEKLSPKPGTGE 494
            P S           HT         V N ++ ++S      N     + E  SP P    
Sbjct: 2285 PVS-----------HT--------LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEG 2325

Query: 495  PVLSLHYSTEGTT----------------TSTIKLNFTDEWSSIASSSRGIGSHCKSEGQ 538
              +    S+EG T                TST+     D  + + + S+   S   +   
Sbjct: 2326 TSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTA--- 2382

Query: 539  EESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLD 598
            +++ +P S+    EG +   +   S+  V   +    +  PV+    +T S + ++ P  
Sbjct: 2383 DDTSMPTSTYS--EGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSP-- 2438

Query: 599  SNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGP 658
              + E   +            AS   +  P  S +  T S T  + + P       ++ P
Sbjct: 2439 -TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSP 2497

Query: 659  SAHEE------TSTRDSALQDTDDSDDDPVLIPGA 687
            +  E+      T++  S L  +      PV  P A
Sbjct: 2498 TTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 72/309 (23%), Positives = 122/309 (39%), Gaps = 29/309 (9%)

Query: 369 SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDT-PAEQFLQPSTSSTMSAQ---AHST 424
           S P GG++      L  +P S  L VS  A  + T PA   +   TS+  S+    A  T
Sbjct: 268 SAPSGGSTP-----LTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGT 322

Query: 425 SSPTES--PHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNN 482
           S PT +    STPL S+P S    +       +    D+ S++V       SL    +  
Sbjct: 323 SIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDT-STLVTTSTEPSSLPTTAEAT 381

Query: 483 NEKLSPKPGTGEPVLSLHYST------EGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE 536
           +   S       P+ ++  ST      E +TTSTI +   D  + + ++S    S   +E
Sbjct: 382 SMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPV---DSKTFVTTASEASSSPTTAE 438

Query: 537 GQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKP 596
              ++ +  S+  P EG +   +   S+  V   +    +  PV++   +T S + ++ P
Sbjct: 439 ---DTSIATST--PSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSP 493

Query: 597 LDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEAT 656
               + E N +             S   +  P  S + ST S T  + + P       ++
Sbjct: 494 ---PTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550

Query: 657 GPSAHEETS 665
             +  E TS
Sbjct: 551 SSTTPEGTS 559



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 66/316 (20%), Positives = 115/316 (36%), Gaps = 37/316 (11%)

Query: 371 PRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTES 430
           P   +  S +ST P   S+P    SE +    TP        TS   S  +  ++  T  
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTP------EGTSIPTSTPSEGSTPLTNM 575

Query: 431 PHSTPLLSSPDSEQRQSVEA-SGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPK 489
           P ST L+ S ++    +  A S       S++ SS    +  SM      +      S  
Sbjct: 576 PVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMS 635

Query: 490 PGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQ 549
             T     +L  S+E +T ST  +   D  + + +S+    S   +EG   + +P S+  
Sbjct: 636 VST-----TLVASSEASTLSTTPV---DSNTPVTTSTEATSSSTTAEG---TSMPTSTY- 683

Query: 550 PPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNL 609
             EG +   +   ++  V   +    +  PV+    +T S + ++ P  ++         
Sbjct: 684 -TEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA------- 735

Query: 610 DRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDS 669
                 P E ++   +     +  TS+E++T            T     S H  TST  S
Sbjct: 736 SMPTSTPSEGSTPLTSMPVSKTLLTSSEAST----------LSTTPLDTSTHITTSTEAS 785

Query: 670 ALQDTDDSDDDPVLIP 685
               T +    P+  P
Sbjct: 786 CSPTTTEGTSMPISTP 801



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 77/340 (22%), Positives = 129/340 (37%), Gaps = 31/340 (9%)

Query: 369  SRPRGGTSQSDISTLPTVP--SSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSS 426
            S P  GT+      + T P  SS    +S T ++  TP     + +TSS  +A+  S  +
Sbjct: 1742 STPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTE-ATSSPTTAEGTSIPT 1800

Query: 427  PTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKL 486
             T S   TPL S+P S    +   +   +    DS S VV     S S    +  +    
Sbjct: 1801 STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATS 1860

Query: 487  SPKPG----TGEPVLSLHYSTEGT----TTSTIKLNFTDEWSSIASS-SRGIGSHCKSEG 537
            +P  G    T  PV +   ++  T    TT  +       ++ ++SS +   GS   +  
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920

Query: 538  QEESFVPQSS-------VQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQ-- 588
              E   P +S       V   E ++ +    ++   VT Y +  S+    +     T   
Sbjct: 1921 PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAY 1980

Query: 589  ---SDKFTAKPLDSN---SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNE 642
               S   T+ PL +    S E + L+          + S+E +  P T+  TS +++T  
Sbjct: 1981 SEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPS 2040

Query: 643  NNTNPEPQFQTEATGPSAHE----ETSTRDSALQDTDDSD 678
              T P        T   + E     T+  DS  Q T+ ++
Sbjct: 2041 ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTE 2080



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 69/321 (21%), Positives = 120/321 (37%), Gaps = 37/321 (11%)

Query: 378  SDISTLPTVP--SSPDLEVSETAMEVDTPAEQFLQP----STSSTMSAQAHSTSSPTESP 431
            S+  TL T P  +S  +  S  A    T AE  + P    S  ST+      +++P  SP
Sbjct: 2471 SEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASP 2530

Query: 432  HSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPG 491
             ++ L ++P       V ++       S S +S     + + +  E     +  L   P 
Sbjct: 2531 EASTLSTTPVDSNSPVVTST-----EISSSATSAEGTSMPTSTYSE----GSTPLRSMPV 2581

Query: 492  TGEPVLSLHYSTEGTT--TSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQ 549
            + +P+ S   ST  TT   ++I +  + E SS  ++++       +  +  + +    V 
Sbjct: 2582 STKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVS 2641

Query: 550  P-PEGDSE---------------TKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFT 593
              P   SE               T +   SS   T     +    P E    +T     T
Sbjct: 2642 TMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVST 2701

Query: 594  AKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQT 653
                +S +   +   +D S  V   + S+E +  P T++ TS   +T  + + P      
Sbjct: 2702 TLLANSEASTLSTTPVDTSTPV---TTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILV 2758

Query: 654  EATGPSAHEETSTRDSALQDT 674
             +T P A  E ST  +   DT
Sbjct: 2759 -STLPVASSEASTVSTTAVDT 2778



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 68/326 (20%), Positives = 117/326 (35%), Gaps = 17/326 (5%)

Query: 355  EASEVAQSNRGRGRSRPRGGTSQSDISTLPT----VPSSPDLEVSETAMEVDTPAEQFLQ 410
            EAS    +  G            + ++ +P     V SS    +S T  +  TP   + Q
Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078

Query: 411  PSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQL 470
             S+SST +A   S  + T S  STPL S P S +      +   +    D+   V     
Sbjct: 1079 ASSSST-TADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137

Query: 471  GSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTE---GTTTSTIKLNFTDEWSSIASSSR 527
             S S    +  +     P  GT  P+ S+  ST     +  +T+     D  + +A+S+ 
Sbjct: 1138 ASSSPTTAEGTSIPTSPPSEGT-TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196

Query: 528  GIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINIT 587
               +       E + +P S+  P E  +   +       V   +    + +PV+    +T
Sbjct: 1197 ---ASSPPPTAEVTSMPTST--PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVT 1251

Query: 588  QSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNP 647
             S + ++ P    + E   L    +        S   +    TS + ST   T  +   P
Sbjct: 1252 TSAETSSSP---TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308

Query: 648  EPQFQTEATGPSAHEETSTRDSALQD 673
                   ++ P+  E TS   S   +
Sbjct: 1309 VVTSNEVSSSPTPAEGTSMPTSTYSE 1334



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 54/228 (23%), Positives = 85/228 (37%), Gaps = 18/228 (7%)

Query: 397  TAMEVDTPAEQFLQPSTSSTMSAQAHSTSSP---------TESPHSTPLLSSPDSEQRQS 447
            T+ E  TP+   +  ST  T S Q++ST +P         T S  STPL   P S    +
Sbjct: 3589 TSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVT 3648

Query: 448  VEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPG----TGEPVLSLHY-S 502
            +  +G  +    D+ + V+     S S    +       +P  G    T  PV +    S
Sbjct: 3649 ISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTS 3708

Query: 503  TEGTTTST---IKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
            +EG+T ST   +        +   SSS  + S   S           +         T+ 
Sbjct: 3709 SEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRF 3768

Query: 560  PEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDL 607
            PE S+  +      +S     E   + T  +  T  P+ S + ER+ L
Sbjct: 3769 PESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPM-STTSERSTL 3815



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 72/339 (21%), Positives = 124/339 (36%), Gaps = 34/339 (10%)

Query: 347 DMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAE 406
           D+L+R  ++ S+  ++      +     T+  +     +  ++P++   E+++  DTP  
Sbjct: 46  DVLNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGV 105

Query: 407 QFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV 466
              + + + + +    ++ S T  P ST   SSP + +   V  S       S + + V 
Sbjct: 106 SSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVS 165

Query: 467 NKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
              L S                     E   SL Y  + +T  T     +   S     S
Sbjct: 166 TAPLPSF--------------------EAYTSLTYKVDMSTPLTTSTQASS--SPTTPES 203

Query: 527 RGIGSHCKSEGQEE-SFVPQSSVQPPEGDSET--KAPEESSEDVTKYQEGVS----AENP 579
             I     SEG    + +P S+++    ++ T    P E S  VT   +  S    AE P
Sbjct: 204 TTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGP 263

Query: 580 -VENHINITQSDKFTAKPLDSN---SGERNDLNLDRSCGVPEESASSEKAKEPETSDQTS 635
            + N      S   T  PL      S E + L+   +        S+E +  P T++ TS
Sbjct: 264 SLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS 323

Query: 636 TESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDT 674
             ++T    + P       +T P A  E ST      DT
Sbjct: 324 IPTSTYTEGSTPLTS-TPASTMPVATSEMSTLSITPVDT 361



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 73/339 (21%), Positives = 130/339 (38%), Gaps = 46/339 (13%)

Query: 369  SRPRGGTSQSDISTLPT---VPSSPDLEVS-------ETAMEVDTPAE--QFLQPSTSST 416
            ++P   +  S +ST P    +P +   E S       +T+M + TP+E    L     ST
Sbjct: 2583 TKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642

Query: 417  MSAQAHSTSSPTESPHSTPLL--------SSPDSEQRQSVEAS--GHHTHHQSD---SPS 463
            M   +   S+ + +P  T  L        SSP + +  S+  S  G  +   ++   S +
Sbjct: 2643 MPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTT 2702

Query: 464  SVVNKQLGSMSLDEQQDN----NNEKLSPKPGTGEPVLSLHYST--EGTTTSTIKLNFT- 516
             + N +  ++S      +     + + S  P T E   S+  ST  +G+T  T  L  T 
Sbjct: 2703 LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGT-SMRISTPSDGSTPLTSILVSTL 2761

Query: 517  ----DEWSSIASSS--RGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEES----SED 566
                 E S++++++    I     +E        + +  P    SET  P  S       
Sbjct: 2762 PVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTP 2821

Query: 567  VTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAK 626
            V   + G  +  PV+    +T S K ++ P    + E   + +  +        S   + 
Sbjct: 2822 VASSEAGTLSTTPVDTSTPVTTSTKASSSP---TTAEGIVVPISTASEGSTLLTSIPVST 2878

Query: 627  EPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETS 665
             P  S + ST S T  + + P       ++ P+  E TS
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTS 2917



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 79/371 (21%), Positives = 131/371 (35%), Gaps = 43/371 (11%)

Query: 346 SDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSET------AM 399
           SD  + +     + +      G   P    S+  IS+     S+  L   E        +
Sbjct: 123 SDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKV 182

Query: 400 EVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQS-----------V 448
           ++ TP     Q S+S T + ++ +    T S  STPL S P S  + +           V
Sbjct: 183 DMSTPLTTSTQASSSPT-TPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPV 241

Query: 449 EASGHHT--HHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGT 506
           E S   T     S SP++     L + +        +  L+  P +   V+S   ST  T
Sbjct: 242 EISTPVTISAQASSSPTTAEGPSLSNSA----PSGGSTPLTRMPLSVMLVVSSEASTLST 297

Query: 507 TTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQP---PEGDSETKA---- 559
           T +   +       + +S +   G+   +    E   P +S      P   SE       
Sbjct: 298 TPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSIT 357

Query: 560 PEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPL-----------DSNSGERNDLN 608
           P ++S  VT   E  S     E    +T +    + PL            S +   + + 
Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417

Query: 609 LDRSCGVPEES-ASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTR 667
           +D    V   S ASS      +TS  TST S  +   T+        A+  +++  T+  
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPV 477

Query: 668 DSALQDTDDSD 678
           DS  Q T  ++
Sbjct: 478 DSKTQVTTSTE 488


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 86/403 (21%), Positives = 141/403 (34%), Gaps = 47/403 (11%)

Query: 291 KTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLS 350
           +T SA E  + L +P     R   + +   P A P   RER   ++  +S  + +     
Sbjct: 271 ETISANELTQSLAEPTEHGGRTANENNTPSP-AEPTENRERTANENTTLSPAEPI----- 324

Query: 351 RWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQ 410
              E     A  N     + P      +        P+ P      TA E  TP+    +
Sbjct: 325 ---ENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPA--E 379

Query: 411 PSTSSTMSAQAHSTSSP---TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN 467
           P+     +A  ++T SP   TE    TP  +       ++  +S   T H   +P +  N
Sbjct: 380 PTEHGERTANENTTPSPAEPTEHGERTPFAND------KTTSSSAESTEHGERTPLANEN 433

Query: 468 KQLGSMSLDEQQDNN-NEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
                    E ++   NE  +P P  G        + E TT S ++     E ++   ++
Sbjct: 434 TTPSPAEPTENRERTANENTTPSPA-GPTENRETTANEKTTLSPVEPTENRETTANEKTT 492

Query: 527 RGIGSHCKSEGQEESFVPQ----SSVQPPEGDSETKA-----------PEESSEDVTKYQ 571
                  ++ GQ   F  +    SS +P E    T             P E+ E     +
Sbjct: 493 PSPAEPTEN-GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEK 551

Query: 572 EGVSAENPVENHINITQSDKFTAKPL--DSNSGER----NDLNLDRSCGVPEESASSEKA 625
              S   P EN      +++ T   L   + +G+R    N+     S    E    +  A
Sbjct: 552 TTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLA 611

Query: 626 KE---PETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETS 665
            E   P  ++ T     T   NT P P   TE    +A+E+T+
Sbjct: 612 NENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTT 654



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 89/424 (20%), Positives = 154/424 (36%), Gaps = 50/424 (11%)

Query: 286 TARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRM 345
           TA E  TPS  E  E   + P    +               +E    GE++P  +  +  
Sbjct: 387 TANENTTPSPAEPTEHGERTPFANDKTTSS----------SAESTEHGERTPLAN--ENT 434

Query: 346 SDMLSRWFEEASEVAQSNRGRGRSRPRGG--TSQSDISTLPTVPSSPDLEVSETAMEVDT 403
           +   +   E     A  N     + P     T+ ++ +TL  V  + + E   TA E  T
Sbjct: 435 TPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET--TANEKTT 492

Query: 404 PAEQFLQPSTSSTMSAQAHSTSS---PTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD 460
           P+      +   T  A   +TSS   PTE    TPL +   +        +   T ++  
Sbjct: 493 PSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKT 552

Query: 461 SPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLS---LHYSTEGTTTSTIKLNFTD 517
           +PS     + G     ++    NEK +P     EP  +     ++ E TT+S+ +    +
Sbjct: 553 TPSPAEPTENG-----DRTPLANEKTTPS--LAEPTENGQRTPFANEKTTSSSAEPTEHE 605

Query: 518 EWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA-------------PEESS 564
           E + +A+ +        +E +E +   +++   P G +E +              P E+ 
Sbjct: 606 ERTPLANENTTPSPAEPTENRERT-ANENTTPSPAGPTENREMTANEKTTLFPAEPTENR 664

Query: 565 EDVTKYQEGVSAENPVENHINIT-QSDKFTAKPLD-SNSGERNDLNLDRSCGVPEESASS 622
           E     +   S   P EN       ++K T+   + +  GER  L  + +   P E   +
Sbjct: 665 ERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTEN 724

Query: 623 EK--AKEPET---SDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDS 677
            +  A E  T   ++ T     T   NT P P   TE    +      T  S  + T++ 
Sbjct: 725 RERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENG 784

Query: 678 DDDP 681
              P
Sbjct: 785 KRTP 788



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 91/417 (21%), Positives = 145/417 (34%), Gaps = 58/417 (13%)

Query: 287  ARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMS 346
            A E  T S+ E  E   + P+       + + T   A P   RER   +       +   
Sbjct: 790  ANEKTTSSSAEPTEHAERTPL------ANENTTSSPAEPTENRERTANEKTTQFPAEPTE 843

Query: 347  DMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDT--P 404
            +  S   E+ +           +  R  T+  + +  P  P+  + E++  A E  T  P
Sbjct: 844  NRESTANEKTTPFPAEP-----TENREWTANENTTLSPAEPTEHE-EMTPLANEKTTLSP 897

Query: 405  AEQFLQPS-TSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPS 463
            AE       T  T      S++ PTE    TPL +   +  R      G    ++  +PS
Sbjct: 898  AEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPS 957

Query: 464  SVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIA 523
                 + G  +++E  D       P        L+   +T   T ST     T    +  
Sbjct: 958  PAKPTEHGETTVNE--DTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTP 1015

Query: 524  SSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA-----------PEESSEDVTKYQE 572
            S +       ++    E  +P S  +P E +  T +           P E  E  T   E
Sbjct: 1016 SPAEPTEHGERTPSANEKTIP-SPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANE 1074

Query: 573  GV--SAENPVENHINITQ-SDKFT---AKPLDSNSGERNDLNLDRSCGVPEESASSEKAK 626
             +  S E P E+    T  ++K T   AKP  +  GER           P +  +S  A+
Sbjct: 1075 KITLSPEGPTEHGAKTTSANEKITPSLAKP--TEHGERTT--------SPNDKITSSAAE 1124

Query: 627  EPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETST--RDSALQDTDDSDDDP 681
              E  D+     AT+ N   P P        P  H + +T   +   Q T+ S + P
Sbjct: 1125 STEHRDR-----ATSANVITPAP------AEPIKHAKRTTLAHEKMTQVTEKSTEHP 1170



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 69/314 (21%), Positives = 112/314 (35%), Gaps = 42/314 (13%)

Query: 375 TSQSDISTLPTVPSSPDLEVSETAMEVDTPA------EQFLQPSTSSTMSAQAHSTSSPT 428
           T +SD +  P   S   L+ + T+    T +       Q  Q STS      A   S  T
Sbjct: 179 TRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITA--ASKTT 236

Query: 429 ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNN----NE 484
                TP  S    + R +V +    T    +   ++   +L + SL E  ++     NE
Sbjct: 237 YKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANEL-TQSLAEPTEHGGRTANE 295

Query: 485 KLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVP 544
             +P P   EP  +   +    TT               S +  I +  ++  +  +  P
Sbjct: 296 NNTPSPA--EPTENRERTANENTT--------------LSPAEPIENRERTANENTAPFP 339

Query: 545 QSSVQPPE---GDSETKAPEESSEDVTKYQEGVSAENPVE--NHINITQSDKFTAKPLD- 598
               +  E    ++ T  P E +E   +     +  +P E   H   T ++  T  P + 
Sbjct: 340 AGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEP 399

Query: 599 SNSGER----NDLNLDRSCGVPEESASSEKAKE---PETSDQTSTESATNENNTNPEPQF 651
           +  GER    ND     S    E    +  A E   P  ++ T     T   NT P P  
Sbjct: 400 TEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAG 459

Query: 652 QTEATGPSAHEETS 665
            TE    +A+E+T+
Sbjct: 460 PTENRETTANEKTT 473



 Score = 33.5 bits (75), Expect = 0.89
 Identities = 53/288 (18%), Positives = 100/288 (34%), Gaps = 27/288 (9%)

Query: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHT-HHQSDSPSSVVNKQLGSMSLDEQQ 479
           A ST++  ES     +  +P S+       +G  T   +SD     + K + ++      
Sbjct: 143 ADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTS 202

Query: 480 DN----------NNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGI 529
            +          N++         E + +   +T  TT +  +   T++  +  +S + +
Sbjct: 203 SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLL 262

Query: 530 GSHCKS--EGQEESFVPQSSVQPPEGDSETK---------APEESSEDVTKYQEGVSAEN 578
               K+  E    + + QS  +P E    T           P E+ E        +S   
Sbjct: 263 TKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAE 322

Query: 579 PVENHINITQSDK--FTAKPLDSNSGERNDLNLDRSCGVPEESA--SSEKAKEPETSDQT 634
           P+EN       +   F A P ++     N+ N       P E    ++ +   P  ++ T
Sbjct: 323 PIENRERTANENTAPFPAGPTENREMTANE-NTTLFPAEPTEHGERTANENTTPSPAEPT 381

Query: 635 STESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPV 682
                T   NT P P   TE    +      T  S+ + T+  +  P+
Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPL 429



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 50/249 (20%), Positives = 90/249 (36%), Gaps = 35/249 (14%)

Query: 422 HSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDN 481
           HS   P E P ST +      EQ++    + H     +D P+        S ++D +   
Sbjct: 66  HSGQRPPELPKSTEI-----HEQKRHCNTTRHSK--PTDKPTG------NSKTIDHKSST 112

Query: 482 NNEKLSPKPGTG------EPVLSLHYSTE-GTTTSTIKLNFTDEWSSIASSSRGIGSHCK 534
           +N +  P           +P++    S +   +T+T K +   +  + A  S+    +C+
Sbjct: 113 DNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSK---INCR 169

Query: 535 SEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHI--NITQSDKF 592
                +S V + S        +T  P E S          S +     H   N     K 
Sbjct: 170 KSTTGKSTVTRKS-------DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKS 222

Query: 593 TAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQ 652
           T+ P    +  +      ++ G PEES  +E ++    SD+  T++  N   T    +  
Sbjct: 223 TSFPEKITAASKTTY---KTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELT 279

Query: 653 TEATGPSAH 661
                P+ H
Sbjct: 280 QSLAEPTEH 288


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 86/403 (21%), Positives = 140/403 (34%), Gaps = 47/403 (11%)

Query: 291 KTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLS 350
           +T SA E  + L +P     R   + +   P A P   RER   ++  +S  +       
Sbjct: 333 ETISANELTQSLAEPTEHGGRTANENNTPSP-AEPTENRERTANENTTLSPAEPT----- 386

Query: 351 RWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQ 410
              E     A  N     + P      +        P+ P      TA E  TP+    +
Sbjct: 387 ---ENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPA--E 441

Query: 411 PSTSSTMSAQAHSTSSP---TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN 467
           P+     +A  ++T SP   TE    TP  +       ++  +S   T H   +P +  N
Sbjct: 442 PTEHGERTANENTTPSPAEPTEHGERTPFAND------KTTSSSAESTEHGERTPLANEN 495

Query: 468 KQLGSMSLDEQQDNN-NEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
                    E ++   NE  +P P  G        + E TT S ++     E ++   ++
Sbjct: 496 TTPSPAEPTENRERTANENTTPSPA-GPTENRETTANEKTTLSPVEPTENRETTANEKTT 554

Query: 527 RGIGSHCKSEGQEESFVPQ----SSVQPPEGDSETKA-----------PEESSEDVTKYQ 571
                  ++ GQ   F  +    SS +P E    T             P E+ E     +
Sbjct: 555 PSPAEPTEN-GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEK 613

Query: 572 EGVSAENPVENHINITQSDKFTAKPL--DSNSGER----NDLNLDRSCGVPEESASSEKA 625
              S   P EN      +++ T   L   + +G+R    N+     S    E    +  A
Sbjct: 614 TTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLA 673

Query: 626 KE---PETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETS 665
            E   P  ++ T     T   NT P P   TE    +A+E+T+
Sbjct: 674 NENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTT 716



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 89/425 (20%), Positives = 154/425 (36%), Gaps = 52/425 (12%)

Query: 286 TARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRM 345
           TA E  TPS  E  E   + P    +               +E    GE++P  +  +  
Sbjct: 449 TANENTTPSPAEPTEHGERTPFANDKTTSS----------SAESTEHGERTPLAN--ENT 496

Query: 346 SDMLSRWFEEASEVAQSNRGRGRSRPRGG--TSQSDISTLPTVPSSPDLEVSETAMEVDT 403
           +   +   E     A  N     + P     T+ ++ +TL  V  + + E   TA E  T
Sbjct: 497 TPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET--TANEKTT 554

Query: 404 PAEQFLQPSTSSTMSAQAHSTSS---PTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD 460
           P+      +   T  A   +TSS   PTE    TPL +   +        +   T ++  
Sbjct: 555 PSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKT 614

Query: 461 SPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLS---LHYSTEGTTTSTIKLNFTD 517
           +PS     + G     ++    NEK +P     EP  +     ++ E TT+S+ +    +
Sbjct: 615 TPSPAEPTENG-----DRTPLANEKTTPS--LAEPTENGQRTPFANEKTTSSSAEPTEHE 667

Query: 518 EWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA-------------PEESS 564
           E + +A+ +        +E +E +   +++   P G +E +              P E+ 
Sbjct: 668 ERTPLANENTTPSPAEPTENRERT-ANENTTPSPAGPTENREMTANEKTTLFPAEPTENR 726

Query: 565 EDVTKYQEGVSAENPVENHINIT-QSDKFTAKPLD-SNSGERNDLNLDRSCGVP------ 616
           E     +   S   P EN       ++K T+   + +  GER  L  + +   P      
Sbjct: 727 ERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTEN 786

Query: 617 EESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDD 676
            E  ++EK   P  ++ T     T   NT P P   TE    +      T  S  + T++
Sbjct: 787 RERTANEKTT-PFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTEN 845

Query: 677 SDDDP 681
               P
Sbjct: 846 GKRTP 850



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 71/309 (22%), Positives = 111/309 (35%), Gaps = 32/309 (10%)

Query: 375 TSQSDISTLPTVPSSPDLEVSETAMEVDTPA------EQFLQPSTSSTMSAQAHSTSSPT 428
           T +SD +  P   S   L+ + T+    T +       Q  Q STS      A   S  T
Sbjct: 241 TRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITA--ASKTT 298

Query: 429 ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNN----NE 484
                TP  S    + R +V +    T    +   ++   +L + SL E  ++     NE
Sbjct: 299 YKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANEL-TQSLAEPTEHGGRTANE 357

Query: 485 KLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVP 544
             +P P   EP  +   +    TT +     T+     A+ +        +E +E +   
Sbjct: 358 NNTPSPA--EPTENRERTANENTTLS-PAEPTENRERTANENTAPFPAGPTENREMTANE 414

Query: 545 QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLD-SNSGE 603
            +++ P E       P E  E         S   P E H   T ++  T  P + +  GE
Sbjct: 415 NTTLFPAE-------PTEHGERTANENTTPSPAEPTE-HGERTANENTTPSPAEPTEHGE 466

Query: 604 R----NDLNLDRSCGVPEESASSEKAKE---PETSDQTSTESATNENNTNPEPQFQTEAT 656
           R    ND     S    E    +  A E   P  ++ T     T   NT P P   TE  
Sbjct: 467 RTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENR 526

Query: 657 GPSAHEETS 665
             +A+E+T+
Sbjct: 527 ETTANEKTT 535



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 49/287 (17%), Positives = 105/287 (36%), Gaps = 25/287 (8%)

Query: 421 AHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHT-HHQSDSPSSVVNKQLGSMSLDEQQ 479
           A ST++  ES     +  +P S+       +G  T   +SD     + K + ++      
Sbjct: 205 ADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTS 264

Query: 480 DN----------NNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGI 529
            +          N++         E + +   +T  TT +  +   T++  +  +S + +
Sbjct: 265 SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLL 324

Query: 530 GSHCKS--EGQEESFVPQSSVQPPE------GDSETKAPEESSEDVTKYQEGVSAENPVE 581
               K+  E    + + QS  +P E       ++ T +P E +E+  +     +  +P E
Sbjct: 325 TKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAE 384

Query: 582 NHINITQSDKFTAKPLDSNSGERNDLNLDRSCGV----PEESA--SSEKAKEPETSDQTS 635
              N  ++      P  +   E  ++  + +  +    P E    ++ +   P  ++ T 
Sbjct: 385 PTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTE 444

Query: 636 TESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPV 682
               T   NT P P   TE    +      T  S+ + T+  +  P+
Sbjct: 445 HGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPL 491



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 64/315 (20%), Positives = 111/315 (35%), Gaps = 65/315 (20%)

Query: 422 HSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDN 481
           HS   P E P ST +      EQ++    + H     +D P+        S ++D +   
Sbjct: 128 HSGQRPPELPKSTEI-----HEQKRHCNTTRHSK--PTDKPTG------NSKTIDHKSST 174

Query: 482 NNEKLSPKPGTG------EPVLSLHYSTE-GTTTSTIKLNFTDEWSSIASSSRGIGSHCK 534
           +N +  P           +P++    S +   +T+T K +   +  + A  S+    +C+
Sbjct: 175 DNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSK---INCR 231

Query: 535 SEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHI--NITQSDKF 592
                +S V + S        +T  P E S          S +     H   N     K 
Sbjct: 232 KSTTGKSTVTRKS-------DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKS 284

Query: 593 TAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTES-------------- 638
           T+ P    +  +      ++ G PEES  +E ++    SD+  T++              
Sbjct: 285 TSFPEKITAASKTTY---KTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELT 341

Query: 639 ------------ATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPVLIPG 686
                         NENNT P P   TE    +A+E T+   +   +  +   +    P 
Sbjct: 342 QSLAEPTEHGGRTANENNT-PSPAEPTENRERTANENTTLSPAEPTENRERTANENTAP- 399

Query: 687 ARYRAGPGDRRSAVA 701
             + AGP + R   A
Sbjct: 400 --FPAGPTENREMTA 412


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 91/380 (23%), Positives = 147/380 (38%), Gaps = 45/380 (11%)

Query: 315 DWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNR-----GRGRS 369
           D S  GP+ R E    R G    +   +Q   +   +  + A +    +R      R  S
Sbjct: 117 DDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS 176

Query: 370 RPRGGTS-QSDISTLPTVPSSPDLEVSE-TAMEVDTPAEQFLQPSTSSTMSAQAHSTSSP 427
           +P GG S Q   S    V    D E S     E+D    Q   P +  +    +   S+ 
Sbjct: 177 KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAG 236

Query: 428 TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQ--DNNNEK 485
            +S  S       +SEQ  + ++ G       + PS  + ++      D++   D+NN  
Sbjct: 237 MKSKES-----GENSEQANTQDSGGSQL---LEHPSRKIFRKSRISEEDDRSELDDNN-- 286

Query: 486 LSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEG--QEESFV 543
                 T E V S   STE + +    L      S     S+G       E   QEES  
Sbjct: 287 ------TMEEVKS--DSTENSNSRDTGL------SQPRRDSKGDSQEDSKENLSQEES-- 330

Query: 544 PQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGE 603
              +V  P  +S  +A   S E+ ++ QE V +E+  +N    T    +     DS+S E
Sbjct: 331 --QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTS---YVEDQEDSDSSE 385

Query: 604 RNDLN-LDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHE 662
            +  + L  S     E  +  ++ E     + S ES  +EN+++ E      ++  S  E
Sbjct: 386 EDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE 445

Query: 663 ETSTR--DSALQDTDDSDDD 680
           E+ +   DS  QD+  S +D
Sbjct: 446 ESHSEEDDSDSQDSSRSKED 465


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 91/380 (23%), Positives = 147/380 (38%), Gaps = 45/380 (11%)

Query: 315 DWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNR-----GRGRS 369
           D S  GP+ R E    R G    +   +Q   +   +  + A +    +R      R  S
Sbjct: 101 DDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS 160

Query: 370 RPRGGTS-QSDISTLPTVPSSPDLEVSE-TAMEVDTPAEQFLQPSTSSTMSAQAHSTSSP 427
           +P GG S Q   S    V    D E S     E+D    Q   P +  +    +   S+ 
Sbjct: 161 KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAG 220

Query: 428 TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQ--DNNNEK 485
            +S  S       +SEQ  + ++ G       + PS  + ++      D++   D+NN  
Sbjct: 221 MKSKES-----GENSEQANTQDSGGSQL---LEHPSRKIFRKSRISEEDDRSELDDNN-- 270

Query: 486 LSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEG--QEESFV 543
                 T E V S   STE + +    L      S     S+G       E   QEES  
Sbjct: 271 ------TMEEVKS--DSTENSNSRDTGL------SQPRRDSKGDSQEDSKENLSQEES-- 314

Query: 544 PQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGE 603
              +V  P  +S  +A   S E+ ++ QE V +E+  +N    T    +     DS+S E
Sbjct: 315 --QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTS---YVEDQEDSDSSE 369

Query: 604 RNDLN-LDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHE 662
            +  + L  S     E  +  ++ E     + S ES  +EN+++ E      ++  S  E
Sbjct: 370 EDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE 429

Query: 663 ETSTR--DSALQDTDDSDDD 680
           E+ +   DS  QD+  S +D
Sbjct: 430 ESHSEEDDSDSQDSSRSKED 449


>gi|55741849 WD repeat domain 22 [Homo sapiens]
          Length = 942

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 74/312 (23%), Positives = 122/312 (39%), Gaps = 62/312 (19%)

Query: 16  KRSLGLEDPSRLRSRYLGRR---------EFIQRLKLEATLNV-------HDGCVNTICW 59
           KR  GL    R    +L +R         +  QR +L    N+       H GCVN I +
Sbjct: 2   KRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEF 61

Query: 60  -NDTGEYILSGSDDTKLVISNP----YSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSC 114
            N+ G++++SG DD ++++ +     +SR     ++  H +NIF   F    N K     
Sbjct: 62  SNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAF-NSGNTKVFSGG 120

Query: 115 SGDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIK 174
           + + VI +     D E++       H    Y +   P +   F S  +DG V  +D R +
Sbjct: 121 NDEQVILH-----DVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIR-E 174

Query: 175 TSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRR------------ 222
           +   +  C    L N   A  SV   P  P  LA   S   V ++D R            
Sbjct: 175 SPHGEPFC----LANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGN 230

Query: 223 -MLGTRATGNYAGRGTTGM-VARFIPSHLNN----------------KSCRVTSLCYSED 264
             L +  +  +   GT  + + R +P  L +                 SC + S C++ D
Sbjct: 231 LSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGD 290

Query: 265 GQEILVSYSSDY 276
             + ++S S D+
Sbjct: 291 RDQYILSGSDDF 302



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 30/105 (28%), Positives = 55/105 (52%), Gaps = 14/105 (13%)

Query: 722 LNIRRPLVKMVYKGHRNSRTMIKEANFWGAN--FVMSGSDCGHIFIW-----------DR 768
           ++ R P+ +   +G+ NS TM K   F G    +++SGSD  ++++W            R
Sbjct: 262 IHSRLPVFQFDNQGYFNSCTM-KSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGR 320

Query: 769 HTAEHLMLLEADNHVVNCLQPHPFDPILASSGIDYDIKIWSPLEE 813
                 M+L+    +VN ++ +P   ++ SSG++  IKIWSP ++
Sbjct: 321 VVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQ 365


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 83/397 (20%), Positives = 140/397 (35%), Gaps = 36/397 (9%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSR--PRGG 374
            S T     PES        S   +L+    +  +    EAS    S+ G   +   P G 
Sbjct: 1765 STTASSLGPESTTFHSSPGSTETTLLP--DNTTASGLLEASTPVHSSTGSPHTTLSPAGS 1822

Query: 375  TS-QSDISTLPTVPSSPDL---EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST----SS 426
            T+ Q + +T  + PSS D      + T+  V+        PS++ T    A ST    S 
Sbjct: 1823 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 1882

Query: 427  PTESPHSTPLLSSPDSEQRQSV------EASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
             + + HS+P+ ++      +S       E++ +H+   S            S   +E + 
Sbjct: 1883 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942

Query: 481  NNN---EKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEG 537
            +++     +S  P T   ++    S   +  ST   +F D  ++   S     SH   + 
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 2002

Query: 538  QEESFVP-QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKP 596
                 +P +S+     G+S T      S + T      +     E       S +  A  
Sbjct: 2003 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 2062

Query: 597  LDSNSGERNDLNLDRSCGVPEESASSE----KAKEPETSDQTSTESATNENNTNPEPQFQ 652
            L   S          S GV EES +S             D T+T   +  + T+      
Sbjct: 2063 LSPAS--------TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 2114

Query: 653  TEATGPSAHEETS--TRDSALQDTDDSDDDPVLIPGA 687
            T+ T   A   TS  +++S    +     D  L PG+
Sbjct: 2115 TDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS 2151



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 85/398 (21%), Positives = 139/398 (34%), Gaps = 38/398 (9%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSR--PRGG 374
            S T     PES     G  S   +L+    +  +    EAS    S+ G   +   P G 
Sbjct: 3322 STTASSLGPESTTFHSGPGSTETTLLP--DNTTASGLLEASTPVHSSTGSPHTTLSPAGS 3379

Query: 375  TS-QSDISTLPTVPSSPDLEVSE---TAMEVDTPAEQFLQPSTSSTMSAQAHST----SS 426
            T+ Q + +T  + P+S D   +    T+  V+        PS++ T    A ST    S 
Sbjct: 3380 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 3439

Query: 427  PTESPHSTPLLSSPDSEQRQSV------EASGHHTHHQSDS----PSSVVNKQLGSMSLD 476
             + + HS+P+ ++      +S       E++ +H+   S      P S      G  S  
Sbjct: 3440 ESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES-T 3498

Query: 477  EQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE 536
                +    +S  P T   ++    S   +  ST   +F D  ++   S     SH   +
Sbjct: 3499 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 3558

Query: 537  GQEESFVP-QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAK 595
                  +P +S+     G+S T      S + T      +     E       S +  A 
Sbjct: 3559 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 3618

Query: 596  PLDSNSGERNDLNLDRSCGVPEESASSE----KAKEPETSDQTSTESATNENNTNPEPQF 651
             L   S          S GV EES +S             D T+T   +  + T+     
Sbjct: 3619 TLSPAS--------TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 3670

Query: 652  QTEATGPSAHEET--STRDSALQDTDDSDDDPVLIPGA 687
             T+ T   A   T  S+++S    +     D  L PG+
Sbjct: 3671 STDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGS 3708



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 75/326 (23%), Positives = 119/326 (36%), Gaps = 31/326 (9%)

Query: 367  GRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST 424
            G S P R   S ++ +TLP  P++P L E S T        +  L P+T+++      S+
Sbjct: 2493 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 2552

Query: 425  SSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNE 484
            +S ++ P ST   + PDS    +      H+     SP S     L + +        + 
Sbjct: 2553 TSHSQ-PGSTHTTAFPDS---TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 2608

Query: 485  KLSPKPGTGEPVLS------LHYSTEGTT-----TSTIKLNFTDEWSSIASSSRGIGSHC 533
                 PG+ +  LS      L +  E TT      ST    F D  +S          H 
Sbjct: 2609 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 2668

Query: 534  KSEGQEESFVPQSSVQPP-EGDSETKAPEESSEDVTKYQEGVSAENPVENHINI------ 586
             +     +  P SS  P  +G+S T     +S   T      +A  PVE           
Sbjct: 2669 STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPS-TATAPVEESTTYHRSPGS 2727

Query: 587  TQSDKFTAKPLDSNSGERNDL---NLDRSCGVPEESASSEKAKEPETSDQT---STESAT 640
            T +  F A    S   E++ +   + D S   P  + S+   +   T+ +    STE  T
Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787

Query: 641  NENNTNPEPQFQTEATGPSAHEETST 666
               +T      +   T  S+    +T
Sbjct: 2788 LPGSTTTPGLSEASTTFYSSPRSPTT 2813



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 75/333 (22%), Positives = 113/333 (33%), Gaps = 44/333 (13%)

Query: 371  PRGGTS-QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSS--------TMSAQA 421
            P G T+ Q + +T  + PSS D     T     T    F++PST+S        T    A
Sbjct: 764  PAGSTTRQGESTTFHSWPSSKD-----TRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 818

Query: 422  HSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDN 481
             ST+S      ST   SSP S Q      S   +    +S +S                +
Sbjct: 819  RSTTSGLVE-ESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS--------------HSS 863

Query: 482  NNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEES 541
                +S  P T   ++    S   +  ST   +F D  ++   S     SH   +     
Sbjct: 864  TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI 923

Query: 542  FVP-QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600
             +P +S+     G+S T      S + T      +     E       S +  A  L   
Sbjct: 924  VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA 983

Query: 601  SGERNDLNLDRSCGVPEESASSE----KAKEPETSDQTSTESATNENNTNPEPQFQTEAT 656
            S          S GV EES +S             D T+T   +  + T+      T+ T
Sbjct: 984  S--------TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 1035

Query: 657  GPSAHEETS--TRDSALQDTDDSDDDPVLIPGA 687
               A   TS  +++S    +     D  L PG+
Sbjct: 1036 LLPASTTTSGPSQESTTSHSSSGSTDTALSPGS 1068



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 82/357 (22%), Positives = 128/357 (35%), Gaps = 56/357 (15%)

Query: 367  GRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST 424
            G S P R   S ++ +TLP  P++P L E S T        +  L P+T+++      S+
Sbjct: 4050 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 4109

Query: 425  SSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNE 484
            +S ++ P ST   + PDS     +      +H    S  + ++    + S   QQ     
Sbjct: 4110 TSHSQ-PGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT-- 4166

Query: 485  KLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGI--GSHCKSEGQEESF 542
                 PG  E  L      + T TS +    T   SS  S    +   S   +  QEES 
Sbjct: 4167 -FHSSPGDTETTL----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEEST 4221

Query: 543  V----PQSSVQPPEGDSETKAPEE---------SSEDVTKYQEGVSAENPVENHINITQS 589
                 P SS   P   S T  P E         SS   T +    +     E    +  S
Sbjct: 4222 TFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 4281

Query: 590  -------------------DKFTAKPLDSNSGERNDL-NLDRSCGVPEESA---SSEKAK 626
                                + T  P+ S S E   L     + G+ E+S    SS ++ 
Sbjct: 4282 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 4341

Query: 627  EPETSDQTSTESATNENNTNPEPQ--------FQTEATGPSAHEETSTRDSALQDTD 675
            +   S  ++T S  +E +T    +        F +  T P   +E++   S+   TD
Sbjct: 4342 DTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTD 4398



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 92/398 (23%), Positives = 148/398 (37%), Gaps = 82/398 (20%)

Query: 367  GRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST 424
            G S P R   S ++ +TLP  P++P L E S T        +  L P+T+++      S+
Sbjct: 2967 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 3026

Query: 425  SSPTESPHSTPLLSSPDSEQRQ--SVEASGHHTHHQSD----SPSSVVNKQLGSMSLDEQ 478
            +S ++ P ST   + PDS      S E +  H+   S     SP S     LG  S    
Sbjct: 3027 TSHSQ-PGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFH 3085

Query: 479  QDNNNEKLSPKPGTGEPVLS-LHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEG 537
                + + +  P   + + S L  ++  T +ST  L+ T   +  +S+S G+        
Sbjct: 3086 SSPGDTETTLLP--DDTITSGLVEASTPTHSSTGSLHTT--LTPASSTSAGL-------- 3133

Query: 538  QEESFV----PQSSVQPPEGDSETKAPEE---------SSEDVTKYQEGVSAENPVENHI 584
            QEES      P SS   P     T AP E         SS   T +    +     E   
Sbjct: 3134 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 3193

Query: 585  NITQS-------------------DKFTAKPLDSNSGERNDL-NLDRSCGVPEESA---S 621
             +  S                    + T  P+ S S E   L     + G+ E+S    S
Sbjct: 3194 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 3253

Query: 622  SEKAKEPETSDQTSTESATNENNTNPEPQ--------FQTEATGPSAHEETSTRDSALQD 673
            S ++ +   S  ++T S  +E +T    +        F    T P   +E++   S+   
Sbjct: 3254 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 3313

Query: 674  TDDSDDDPVLIPGA-----------RYRAGPGDRRSAV 700
            TD +     L PG+            + +GPG   + +
Sbjct: 3314 TDTT-----LSPGSTTASSLGPESTTFHSGPGSTETTL 3346



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 86/363 (23%), Positives = 139/363 (38%), Gaps = 46/363 (12%)

Query: 357  SEVAQSNRGRGRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTS 414
            S    +  GRG S   R     ++I+TLP   ++P L E S T           L P++ 
Sbjct: 3844 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 3903

Query: 415  STMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMS 474
            +++     ST+S ++ P ST    SP S     +  S   T   S SP S         +
Sbjct: 3904 TSLGVGEESTTSRSQ-PGSTHSTVSPASTTTPGL--SEESTTVYSSSPGSTETTVFPRST 3960

Query: 475  LDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCK 534
                +         +P +    L     TE +TTS +    T    S AS+  G+ +   
Sbjct: 3961 TTSVRREEPTTFHSRPASTHTTLF----TEDSTTSGLTEESTAFPGSPASTQTGLPATLT 4016

Query: 535  SE--GQEESFVPQSSVQPPEGDSETK-APEESSEDVTKYQEGVSAENPVENHINITQSDK 591
            +   G+E +  P SS     G + TK +P  S+      +   S  +P     + T++  
Sbjct: 4017 TADLGEESTTFPSSS-----GSTGTKLSPARSTTSGLVGESTPSRLSP-----SSTETTT 4066

Query: 592  FTAKPLDSNSGERN----------DLNLD----RSCGVPEESASSEKAKEPETS------ 631
                P   +  E++          D  L      S GV EES++S    +P ++      
Sbjct: 4067 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS--QPGSTHTTAFP 4124

Query: 632  DQTSTESATNENNTNPEPQFQTEAT-GPSAHEETST-RDSALQDTDDSDDDPVLIPGARY 689
            D T+T   + E  T+   Q  TEAT  P +   +S  + S    +   D +  L+P    
Sbjct: 4125 DSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 4184

Query: 690  RAG 692
             +G
Sbjct: 4185 TSG 4187



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 82/357 (22%), Positives = 127/357 (35%), Gaps = 56/357 (15%)

Query: 367  GRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST 424
            G S P R   S ++ +TLP  P++P L E S T        +  L P+T+++      S+
Sbjct: 1410 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 1469

Query: 425  SSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNE 484
            +S ++ P ST   + PDS     +      +H    S  + ++    + S   QQ     
Sbjct: 1470 TSHSQ-PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT-- 1526

Query: 485  KLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGI--GSHCKSEGQEESF 542
                 PG  E  L      + T TS +    T   SS  S    +   S   +  QEES 
Sbjct: 1527 -FHSSPGDTETTL----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 1581

Query: 543  V----PQSSVQPPEGDSETKAPEE---------SSEDVTKYQEGVSAENPVENHINITQS 589
                 P SS   P     T AP E         SS   T +    +     E    +  S
Sbjct: 1582 TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 1641

Query: 590  -------------------DKFTAKPLDSNSGERNDL-NLDRSCGVPEESA---SSEKAK 626
                                + T  P+ S S E   L     + G+ E+S    SS ++ 
Sbjct: 1642 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 1701

Query: 627  EPETSDQTSTESATNENNTNPEPQ--------FQTEATGPSAHEETSTRDSALQDTD 675
            +   S  ++T S  +E +T    +        F    T P   +E++   S+   TD
Sbjct: 1702 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 1758



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 70/331 (21%), Positives = 112/331 (33%), Gaps = 38/331 (11%)

Query: 369  SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
            +R    T     +  P   +SP L+   TA +   PA     PS  ST +A    +++  
Sbjct: 3747 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH-PASTHTTPSPPSTATAPVEESTTYH 3805

Query: 429  ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD----SPSSVVNKQLG-SMSLDEQQDNNN 483
             SP STP    P S             H   D    +PSS  +   G   S   +    +
Sbjct: 3806 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 3865

Query: 484  EKLSPKPG-TGEPVLS----LHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE-- 536
             +++  PG T  P LS      YS+  + T+T+        S  + +S G+G    +   
Sbjct: 3866 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL--------SPASMTSLGVGEESTTSRS 3917

Query: 537  --GQEESFVPQSSVQPP-------------EGDSETKA-PEESSEDVTKYQEGVSAENPV 580
              G   S V  +S   P              G +ET   P  ++  V + +       P 
Sbjct: 3918 QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPA 3977

Query: 581  ENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESAT 640
              H  +   D  T   L   S            G+P    +++  +E  T   +S  + T
Sbjct: 3978 STHTTLFTEDS-TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 4036

Query: 641  NENNTNPEPQFQTEATGPSAHEETSTRDSAL 671
              +            + PS    +ST  + L
Sbjct: 4037 KLSPARSTTSGLVGESTPSRLSPSSTETTTL 4067



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 70/316 (22%), Positives = 113/316 (35%), Gaps = 38/316 (12%)

Query: 369  SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
            +R    T     +  P   +SP L+   TA +   PA     PS  ST +A    +++  
Sbjct: 2190 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH-PASTHTTPSPPSTATAPVEESTTYH 2248

Query: 429  ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD----SPSSVVNKQLG-SMSLDEQQDNNN 483
             SP STP    P S             H   D    +PSS  +   G   S   +    +
Sbjct: 2249 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 2308

Query: 484  EKLSPKPG-TGEPVLS----LHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQ 538
             +++  PG T  P LS      YS+  + T+T+        S  + +S G+G    +  +
Sbjct: 2309 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL--------SPASMTSLGVGEE-STTSR 2359

Query: 539  EESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLD 598
             +     S+V P    + T  P  S E  T Y     +          T++  F   P  
Sbjct: 2360 SQPGSTHSTVSP----ASTTTPGLSEESTTVYSSSPGS----------TETTVFPRTPTT 2405

Query: 599  SNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGP 658
            S  GE       R    P  + ++   ++  TS  T   +A   +  + +       T  
Sbjct: 2406 SVRGEEPTTFHSR----PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 2461

Query: 659  SAHEETSTRDSALQDT 674
               EE++T  S+   T
Sbjct: 2462 DLGEESTTFPSSSGST 2477



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/331 (21%), Positives = 111/331 (33%), Gaps = 38/331 (11%)

Query: 369  SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
            +R    T     +  P   +SP L+   TA +   PA     PS  ST +A    +++  
Sbjct: 1107 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH-PASTHTTPSPPSTATAPVEESTTYH 1165

Query: 429  ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD----SPSSVVNKQLG-SMSLDEQQDNNN 483
             SP STP    P S             H   D    +PSS  +   G   S   +    +
Sbjct: 1166 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 1225

Query: 484  EKLSPKPG-TGEPVLS----LHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE-- 536
             +++  PG T  P LS      YS+  + T+T+        S  + +S G+G    +   
Sbjct: 1226 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL--------SPASMTSLGVGEESTTSRS 1277

Query: 537  --GQEESFVPQSSVQPP-------------EGDSETKA-PEESSEDVTKYQEGVSAENPV 580
              G   S V  +S   P              G +ET   P  ++  V   +       P 
Sbjct: 1278 QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPA 1337

Query: 581  ENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESAT 640
              H  +   D  T   L   S            G+P    +++  +E  T   +S  + T
Sbjct: 1338 STHTTLFTEDS-TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 1396

Query: 641  NENNTNPEPQFQTEATGPSAHEETSTRDSAL 671
              +            + PS    +ST  + L
Sbjct: 1397 KLSPARSTTSGLVGESTPSRLSPSSTETTTL 1427



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 66/444 (14%)

Query: 237  TTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPS-- 294
            T+G+V    PS L+  S   T+L  S     +    ++ Y     P D T     T S  
Sbjct: 1405 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP-DATLSPATTTSSG 1463

Query: 295  -AEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWF 353
             +EE      QP             T   A P+S    D  Q P  S   + S   +   
Sbjct: 1464 VSEESSTSHSQP-----------GSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT--L 1510

Query: 354  EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQ------ 407
               S  A S    G+      +S  D  T       PD  ++   +E  TP         
Sbjct: 1511 SPGSTTASS---LGQQSTTFHSSPGDTET----TLLPDDTITSGLVEASTPTHSSTGSLH 1563

Query: 408  -FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV 466
              L P++S++   Q  ST+  +  P S+    SP       VE S   T+H   S +   
Sbjct: 1564 TTLTPASSTSAGLQEESTTFQS-WPSSSDTTPSPPGTTAAPVEVS--TTYHSRPSSTPTT 1620

Query: 467  NKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
            +    S +L   +++     SP   TG  +    + T   T+  +    T   SS ++ +
Sbjct: 1621 HFSASSTTLGRSEESTTVHSSP-GATGTAL----FPTRSATSVLVGEPTTSPISSGSTET 1675

Query: 527  RGI-GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHIN 585
              + GS   +   E+S    SS + P+    T +P  ++      +   S   P   H  
Sbjct: 1676 TALPGSTTTAGLSEKSTTFYSSPRSPD---TTLSPASTTSSGVSEESTTSHSRPGSTH-- 1730

Query: 586  ITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNT 645
             T     T  P                 GV +ES +S  +  P ++D T +  +T  ++ 
Sbjct: 1731 TTAFPGSTTMP-----------------GVSQESTASHSS--PGSTDTTLSPGSTTASSL 1771

Query: 646  NPEPQFQTEATGPSAHEETSTRDS 669
             PE    T  + P + E T   D+
Sbjct: 1772 GPES--TTFHSSPGSTETTLLPDN 1793



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 102/455 (22%), Positives = 161/455 (35%), Gaps = 66/455 (14%)

Query: 226  TRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDD 285
            T  T + A   T+G+V    PS L+  S   T+L  S     +    ++ Y     P D 
Sbjct: 2951 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP-DA 3009

Query: 286  TARELKTPS---AEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLM 342
            T     T S   +EE      QP             T   A P+S       Q P  S  
Sbjct: 3010 TLSPATTTSSGVSEESSTSHSQP-----------GSTHTTAFPDSTTTSGLSQEPTASHS 3058

Query: 343  QRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVD 402
             + S   +      S  A S    G+      +S  D  T       PD  ++   +E  
Sbjct: 3059 SQGSTEAT--LSPGSTTASS---LGQQSTTFHSSPGDTET----TLLPDDTITSGLVEAS 3109

Query: 403  TPAEQ-------FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHT 455
            TP           L P++S++   Q  ST+  +  P S+    SP       VE S   T
Sbjct: 3110 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQS-WPSSSDTTPSPPGTTAAPVEVS--TT 3166

Query: 456  HHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNF 515
            +H   S +   +    S +L   +++     SP   TG  +    + T   T+  +    
Sbjct: 3167 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTAL----FPTRSATSVLVGEPT 3221

Query: 516  TDEWSSIASSSRGI-GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGV 574
            T   SS ++ +  + GS   +   E+S    SS + P+    T +P  ++      +   
Sbjct: 3222 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD---TTLSPASTTSSGVSEESTT 3278

Query: 575  SAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQT 634
            S   P   H   T     T  P                 GV +ES +S  +  P ++D T
Sbjct: 3279 SHSRPGSTH--TTAFPGSTTMP-----------------GVSQESTASHSS--PGSTDTT 3317

Query: 635  STESATNENNTNPEPQFQTEATGPSAHEETSTRDS 669
             +  +T  ++  PE    T  +GP + E T   D+
Sbjct: 3318 LSPGSTTASSLGPES--TTFHSGPGSTETTLLPDN 3350



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 66/444 (14%)

Query: 237  TTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPS-- 294
            T+G+V    PS L+  S   T+L  S     +    ++ Y     P D T     T S  
Sbjct: 4045 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP-DATLSPATTTSSG 4103

Query: 295  -AEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWF 353
             +EE      QP             T   A P+S       Q P  S   + S   +   
Sbjct: 4104 VSEESSTSHSQP-----------GSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT--L 4150

Query: 354  EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQ------ 407
               S  A S    G+      +S  D  T       PD  ++   +E  TP         
Sbjct: 4151 SPGSTTASS---LGQQSTTFHSSPGDTET----TLLPDDTITSGLVEASTPTHSSTGSLH 4203

Query: 408  -FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV 466
              L P++S++   Q  ST+  +  P S+    SP S     VE S   T+H   S +   
Sbjct: 4204 TTLTPASSTSTGLQEESTTFQS-WPSSSDTTPSPPSTTAVPVEVS--TTYHSRPSSTPTT 4260

Query: 467  NKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
            +    S +L   +++     SP   TG  +    + T   T+  +    T   SS ++ +
Sbjct: 4261 HFSASSTTLGRSEESTTVHSSP-GATGTAL----FPTRSATSVLVGEPTTSPISSGSTET 4315

Query: 527  RGI-GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHIN 585
              + GS   +   E+S    SS + P+    T +P  ++      +   S   P   H  
Sbjct: 4316 TALPGSTTTAGLSEKSTTFYSSPRSPD---TTLSPASTTSSGVSEESTTSHSRPGSMHTT 4372

Query: 586  ITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNT 645
               S   T  P                 GV +ES +S  +  P ++D T +  +T  ++ 
Sbjct: 4373 AFPSS--TTMP-----------------GVSQESTASHSS--PGSTDTTLSPGSTTASSL 4411

Query: 646  NPEPQFQTEATGPSAHEETSTRDS 669
             PE    T  + P + E T   D+
Sbjct: 4412 GPES--TTFHSSPGSTETTLLPDN 4433



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 107/493 (21%), Positives = 170/493 (34%), Gaps = 43/493 (8%)

Query: 226  TRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDD 285
            T  T + A   T+G+V    PS L+  S   T+L  S     +    ++ Y     P D 
Sbjct: 2477 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP-DA 2535

Query: 286  TARELKTPS---AEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLM 342
            T     T S   +EE      QP         D S T P     S        S + +L+
Sbjct: 2536 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD-STTTPGLSRHSTTSHSSPGSTDTTLL 2594

Query: 343  QRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQ----SDISTLPTVPSS------PDL 392
               S   S   +E++    S      +   G T+      + +T  + P S      PD 
Sbjct: 2595 P-ASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS 2653

Query: 393  EVSETAMEVDTPAEQ-------FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQR 445
              S   +E  T            L P++S++   Q  ST+  T  P ST    SP S   
Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTH-PASTHTTPSPPSTAT 2712

Query: 446  QSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEG 505
              VE S   T+H+S   +   +    S +    + +     SP   +G    S H +T G
Sbjct: 2713 APVEES--TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP-DASGTTPSSAHSTTSG 2769

Query: 506  ---TTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEE 562
               +TTS I    T E +++  S+   G        E S    SS   P   + T +P  
Sbjct: 2770 RGESTTSRISPGST-EITTLPGSTTTPGL------SEASTTFYSS---PRSPTTTLSPAS 2819

Query: 563  SSEDVTKYQEGVSAENPVENHINITQSDKFT-AKPLDSNSGERNDLNLDRSCGVPEESAS 621
             +      +   S   P   H  ++ +   T     +S +   +      +   P  + +
Sbjct: 2820 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 2879

Query: 622  SEKAKEPET--SDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDD 679
            S + +EP T  S   ST +     ++      +     P +   T T   A   T D  +
Sbjct: 2880 SVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 2939

Query: 680  DPVLIPGARYRAG 692
            +    P +    G
Sbjct: 2940 ESTTFPSSSGSTG 2952



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 84/393 (21%), Positives = 131/393 (33%), Gaps = 43/393 (10%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSR--PRGG 374
            S T     PES        S   +L+    +  +    EAS    S+ G   +   P G 
Sbjct: 4405 STTASSLGPESTTFHSSPGSTETTLLP--DNTTASGLLEASTPVHSSTGSPHTTLSPAGS 4462

Query: 375  TS-QSDISTLPTVPSSPDLEVSE---TAMEVDTPAEQFLQPSTSSTMSAQAHST----SS 426
            T+ Q + +T  + P+S D   +    T+  V+        PS++ T    A ST    S 
Sbjct: 4463 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 4522

Query: 427  PTESPHSTPLLSSPDSEQRQSV------EASGHHTHHQSDS----PSSVVNKQLGSMSLD 476
             + + HS+P+ ++      +S       E++ +H+   S      P S      G  S  
Sbjct: 4523 ESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES-T 4581

Query: 477  EQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE 536
                +    +S  P T   ++    S   +  ST   +F D  ++   S     SH   +
Sbjct: 4582 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 4641

Query: 537  GQEESFVP-QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAK 595
                  +P +S+     G+S T      S + T      +     E       S   T  
Sbjct: 4642 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPT 4701

Query: 596  PLDSNSGERNDLNLDRSCGVPEESA---SSEKAKEPETSDQTSTESATNENNT------- 645
               S S          + G  EES    SS  A     S   ST S   E +T       
Sbjct: 4702 THFSAS--------STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 4753

Query: 646  -NPEPQFQTEATGPSAHEETSTRDSALQDTDDS 677
                  F   +T     EE+ T  S+   T  S
Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISS 4786



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 69/299 (23%), Positives = 108/299 (36%), Gaps = 34/299 (11%)

Query: 384  PTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSE 443
            P    SP    S    E  T +    +P ++ T +A   ST++P  S HST   SSP S 
Sbjct: 3616 PATTLSPASTTSSGVSEESTTSHS--RPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGST 3672

Query: 444  QRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGT----GEPVLSL 499
                + AS   T   S   S+  +   GS          +  LSP   T    G+   + 
Sbjct: 3673 DTTLLPAS--TTTSGSSQESTTSHSSSGS---------TDTALSPGSTTALSFGQESTTF 3721

Query: 500  HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
            H S+ G+T +T+  + T     + +S+R    H  +     +  P SS  P      T  
Sbjct: 3722 H-SSPGSTHTTLFPDSTTSSGIVEASTR---VHSSTGSPRTTLSPASSTSPGLQGESTAF 3777

Query: 560  PEESSEDVTKYQEGVSAENPVENHINI------TQSDKFTAKPLDSNSGERNDL---NLD 610
                +   T      +A  PVE           T +  F A    S   E++ +   + D
Sbjct: 3778 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 3837

Query: 611  RSCGVPEESASSEKAKEPETSDQT---STESATNENNTNPEPQFQTEATGPSAHEETST 666
             S   P  + S+   +   T+ +    STE  T   +T      +   T  S+    +T
Sbjct: 3838 ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 3896



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 66/299 (22%), Positives = 106/299 (35%), Gaps = 34/299 (11%)

Query: 384  PTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSE 443
            P    SP    S    E  T +    +P ++ T +A   ST++P  S HST   SSP S 
Sbjct: 976  PATTLSPASTTSSGVSEESTTSRS--RPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGST 1032

Query: 444  QRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGT----GEPVLSL 499
                + AS   +    +S +S                + +  LSP   T    G+   + 
Sbjct: 1033 DTTLLPASTTTSGPSQESTTS-----------HSSSGSTDTALSPGSTTALSFGQESTTF 1081

Query: 500  HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
            H S  G+T +T+  + T     + +S+R    H  +     +  P SS  P      T  
Sbjct: 1082 H-SNPGSTHTTLFPDSTTSSGIVEASTR---VHSSTGSPRTTLSPASSTSPGLQGESTAF 1137

Query: 560  PEESSEDVTKYQEGVSAENPVENHINI------TQSDKFTAKPLDSNSGERNDL---NLD 610
                +   T      +A  PVE           T +  F A    S   E++ +   + D
Sbjct: 1138 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 1197

Query: 611  RSCGVPEESASSEKAKEPETSDQT---STESATNENNTNPEPQFQTEATGPSAHEETST 666
             S   P  + S+   +   T+ +    STE  T   +T      +   T  S+    +T
Sbjct: 1198 ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 34/299 (11%)

Query: 384  PTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSE 443
            P    SP    S    E  T +    +P ++ T +A   ST++P  S HST   SSP S 
Sbjct: 2059 PATTLSPASTTSSGVSEESTTSHS--RPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGST 2115

Query: 444  QRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGT----GEPVLSL 499
                + AS   +    +S +S                + +  LSP   T    G+   + 
Sbjct: 2116 DTTLLPASTTTSGPSQESTTS-----------HSSPGSTDTALSPGSTTALSFGQESTTF 2164

Query: 500  HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
            H S+ G+T +T+  + T     + +S+R    H  +     +  P SS  P      T  
Sbjct: 2165 H-SSPGSTHTTLFPDSTTSSGIVEASTR---VHSSTGSPRTTLSPASSTSPGLQGESTAF 2220

Query: 560  PEESSEDVTKYQEGVSAENPVENHINI------TQSDKFTAKPLDSNSGERNDL---NLD 610
                +   T      +A  PVE           T +  F A    S   E++ +   + D
Sbjct: 2221 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 2280

Query: 611  RSCGVPEESASSEKAKEPETSDQT---STESATNENNTNPEPQFQTEATGPSAHEETST 666
             S   P  + S+   +   T+ +    STE  T   +T      +   T  S+    +T
Sbjct: 2281 ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 2339



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 55/261 (21%), Positives = 96/261 (36%), Gaps = 34/261 (13%)

Query: 412  STSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV----- 466
            S  ST SA     +S   SP ST     PDS            +H   D+  ++V     
Sbjct: 4593 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 4652

Query: 467  --NKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLS---------------LHYSTEGTTTS 509
              +  LG  +       + E  +    T  P LS                H+S   TT  
Sbjct: 4653 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLG 4712

Query: 510  TIKLNFTDEWSSIASSSRGIGSHCKSEG-QEESFVPQSSVQPPEGDSETKAPEESSEDVT 568
              + + T   S +A+++    +   + G  EES    SS     G ++T    ESS    
Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS----PGSTQTMHFPESSTASG 4768

Query: 569  KYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEP 628
            + +E  ++ +   + I+   S   T+  ++  +   +      +   PE S +S +++E 
Sbjct: 4769 RSEESRTSHSSTTHTISSPPST--TSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEE- 4825

Query: 629  ETSDQTSTESATNENNTNPEP 649
                 T++ S+ + N   P P
Sbjct: 4826 ----STASHSSPDTNGITPLP 4842



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 60/303 (19%), Positives = 105/303 (34%), Gaps = 43/303 (14%)

Query: 381  STLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSP 440
            +  P+  + P +    TA      +        S+T S+    +++   SP ST     P
Sbjct: 4372 TAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP 4431

Query: 441  DSEQRQSVEASGHHTHHQSDSPSSVVN-----KQLGSMSLDEQQDNNNEKLSPKPGTGEP 495
            D+     +  +    H  + SP + ++      + G  +  +   N+ +     P T   
Sbjct: 4432 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 4491

Query: 496  VLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDS 555
             + L  ++ G+ +ST   +F       ++SS  +G        EES    SS   P   +
Sbjct: 4492 FVELSTTSHGSPSSTPTTHF-------SASSTTLGR------SEESTTVHSS---PVATA 4535

Query: 556  ETKAPEESS-----EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLD 610
             T +P  S+     E+ T Y     +          TQ+  F      S  GE +  +  
Sbjct: 4536 TTPSPARSTTSGLVEESTTYHSSPGS----------TQTMHFPESNTTSGRGEESTTSHS 4585

Query: 611  RSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSA 670
             +      + S+  A      + TS  S+     T   P   T     S   E ST   +
Sbjct: 4586 STTHTISSAPSTTSAL---VEEPTSYHSSPGSTATTHFPDSST----TSGRSEESTASHS 4638

Query: 671  LQD 673
             QD
Sbjct: 4639 SQD 4641



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 73/331 (22%), Positives = 123/331 (37%), Gaps = 43/331 (12%)

Query: 369 SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
           S P   ++ S  +TL   PSS      E       P+ +   P+ S T SA    +++  
Sbjct: 392 STPVHSSTGSPHTTLS--PSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYH 449

Query: 429 ESPHSTPL--LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKL 486
            SP STP    S+  +    S E++  H+     SP +       + S        +   
Sbjct: 450 SSPSSTPTTHFSASSTTLGHSEESTPVHS-----SPVATATTPPPARSATSGHVEESTAY 504

Query: 487 SPKPGTGEPVLSLHYSTEGTT------TSTIKLNFTDEWSSIASSSRGIG--SHCKSEGQ 538
              PG+ +   ++H+    TT      ++T   + T   SS  S++  +   S+  S G 
Sbjct: 505 HRSPGSTQ---TMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS 561

Query: 539 EES--FVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKP 596
            E+  F   S++    G SE      SS D        +   P  +  ++   D  T  P
Sbjct: 562 TETTHFRDSSTI---SGRSEESKASHSSPDAM-----ATTVLPAGSTPSVLVGDS-TPSP 612

Query: 597 LDSNSGERNDL-NLDRSCGVPEESA---SSEKAKEPETSDQTSTESATNENNTNPEPQ-- 650
           + S S E   L       G+ E+S    SS ++ +      + T S  +E +T    +  
Sbjct: 613 ISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG 672

Query: 651 ------FQTEATGPSAHEETSTRDSALQDTD 675
                 F    T P   +E++   S+   TD
Sbjct: 673 STHTTAFPGSTTMPGLSQESTASHSSPGPTD 703



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 61/303 (20%), Positives = 98/303 (32%), Gaps = 57/303 (18%)

Query: 412  STSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV----- 466
            S  ST SA     +S   SP ST     PDS            +H   D+  ++V     
Sbjct: 870  SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 929

Query: 467  --NKQLGSMSLDEQQDNNNEKL-----SPKPGTGEPVLSLH------------------- 500
              +  LG  +       + E       +  PG  E   + H                   
Sbjct: 930  TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSG 989

Query: 501  YSTEGTTT-----STIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQS-SVQPPEGD 554
             S E TT+     ST    F D  ++   S     SH      + + +P S +   P  +
Sbjct: 990  VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 1049

Query: 555  SETKAPEESSEDVTKYQEGVSA-----------ENPVENHINITQSDKFTAKPLDSNSGE 603
            S T      S D        +A            NP   H  +      ++  +++++  
Sbjct: 1050 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST-- 1107

Query: 604  RNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEE 663
                 +  S G P  + S   +  P    + ST   T+  +T+  P   + AT P   EE
Sbjct: 1108 ----RVHSSTGSPRTTLSPASSTSPGLQGE-STAFQTHPASTHTTPSPPSTATAPV--EE 1160

Query: 664  TST 666
            ++T
Sbjct: 1161 STT 1163



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 67/322 (20%), Positives = 115/322 (35%), Gaps = 59/322 (18%)

Query: 369  SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
            S  R G++ +  +  P   + P +    TA      +        S+T S+    +++  
Sbjct: 1722 SHSRPGSTHT--TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 1779

Query: 429  ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN-----KQLGSMSLDEQQDNNN 483
             SP ST     PD+     +  +    H  + SP + ++      + G  +  +   ++ 
Sbjct: 1780 SSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSK 1839

Query: 484  EKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFV 543
            + +   P T    + L  ++ G+ +ST   +F       ++SS  +G        EES  
Sbjct: 1840 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHF-------SASSTTLGR------SEESTT 1886

Query: 544  PQSSVQPPEGDSETKAPEESS-----EDVTKYQEGVSAENPVENHINITQSDKFTAKPLD 598
              SS   P   + T +P  S+     E+ T Y     +          TQ+  F   P  
Sbjct: 1887 VHSS---PVATATTPSPARSTTSGLVEESTAYHSSPGS----------TQTMHF---PES 1930

Query: 599  SNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEAT-- 656
            S +  R+           EES +S  +     S   ST SA  E  T+      + AT  
Sbjct: 1931 STASGRS-----------EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTH 1979

Query: 657  -----GPSAHEETSTRDSALQD 673
                   S   E ST   + QD
Sbjct: 1980 FPDSSTTSGRSEESTASHSSQD 2001



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 54/282 (19%), Positives = 101/282 (35%), Gaps = 25/282 (8%)

Query: 378  SDISTLP-TVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPL 436
            +D + LP +  +S   + S T+       +  L P +++ +S    ST+  + SP ST  
Sbjct: 3672 TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS-SPGSTHT 3730

Query: 437  LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNK--------QLGSMSLDEQQDNNNEKLSP 488
               PDS     +  +    H  + SP + ++         Q  S +      + +   SP
Sbjct: 3731 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP 3790

Query: 489  KPGTGEPV--LSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQS 546
                  PV   + ++ + G+T +T   +F    ++   S +    H   +    +     
Sbjct: 3791 PSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 3847

Query: 547  SVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERND 606
            S     G+S T      S ++T      +     E       S +     L   S     
Sbjct: 3848 STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS----- 3902

Query: 607  LNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPE 648
                 S GV EES +S    +P ++  T + ++T     + E
Sbjct: 3903 ---MTSLGVGEESTTSR--SQPGSTHSTVSPASTTTPGLSEE 3939



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 13/142 (9%)

Query: 381  STLPTVPSSPDLEVSETAMEVDTPA-EQFLQPS--TSSTMSAQAHSTSSPTESPHSTPLL 437
            +TL +  ++P L    T +   + + +Q L P+  TSS++S +  S  S  ES H+T   
Sbjct: 4866 TTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFP 4925

Query: 438  SSPDSEQRQSVEASGHHTHHQSD---SPSSVVNKQLGS--MSLDEQQDNNNEKLSPK--- 489
            +S  +        + H     ++   SP S+          +   Q  +    +SP    
Sbjct: 4926 ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTT 4985

Query: 490  -PGTGEPVLSLHYSTEGTTTST 510
             PG  E   +  YS+ G+T +T
Sbjct: 4986 VPGLSEESTTF-YSSPGSTETT 5006


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 78/382 (20%), Positives = 135/382 (35%), Gaps = 23/382 (6%)

Query: 354 EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPST 413
           EE  + A+   G+      GG  +          S P  E +    E  +P ++  + S 
Sbjct: 472 EEEEKEAKEEEGK---EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK-SP 527

Query: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM 473
           +   S +     SP E   S     SP  E+ +S   +      ++ SP+ V + +    
Sbjct: 528 AEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586

Query: 474 SLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHC 533
              E+  +  E  SP+     PV       E  + +  K    +E  S A          
Sbjct: 587 PAKEEAKSPAEAKSPEKAKS-PV-----KEEAKSPAEAKSPVKEEAKSPAEVKSP--EKA 638

Query: 534 KSEGQEESFVPQSSVQPPEGDSETKAPEESSEDV-TKYQEGVSAENPVENHINITQSDKF 592
           KS  +EE+  P+ +  P +   E K+PE++   V  + +    A++PV+      +  K 
Sbjct: 639 KSPTKEEAKSPEKAKSPEK--EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696

Query: 593 TAK-----PLDSNSGERNDLNLDRSCGVP--EESASSEKAKEPETSDQTSTESATNENNT 645
             K     P  + S  + +         P  EE+ + EKAK P   +  S E A +    
Sbjct: 697 PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756

Query: 646 NPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQE 705
                   EA  P+  E  S  D   +       + V  P         D ++    I +
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816

Query: 706 FFRRRKERKEMEELDTLNIRRP 727
               +   KE E+   + ++ P
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEP 838



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 74/406 (18%), Positives = 154/406 (37%), Gaps = 42/406 (10%)

Query: 289  ELKTPSAEERRE--ELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMS 346
            E K+P  EE +   E++ P   +   + +         PE E  +  E++ +    +  S
Sbjct: 617  EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676

Query: 347  DMLSRWFEEAS----EVAQSN-RGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEV 401
               ++   +A     E A+S  +   +S  +  +   + +  P    SP  E ++T  + 
Sbjct: 677  PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736

Query: 402  DTPA-------EQFLQPSTSSTMSAQAHSTSSPTESPHSTPL------LSSPDSEQRQSV 448
             +P        E+   P  + T+  ++    +P +    +P         SP  E+ +S 
Sbjct: 737  KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796

Query: 449  EASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNE-KLSPKPGTGEPVLSLHYSTEGTT 507
            E +       + +P   + K+    S  ++++   E K+   P   E         E   
Sbjct: 797  EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE---------EEKA 847

Query: 508  TSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDV 567
             +T K   T+E               K + +E+    + +V+ P+ +S+ +A +E +ED 
Sbjct: 848  PATPK---TEEKKDSKKEEAPKKEAPKPKVEEKK---EPAVEKPK-ESKVEAKKEEAEDK 900

Query: 568  TKY---QEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEES-ASSE 623
             K    ++   A+  V+      +  +   K  D    +      ++    PE+     E
Sbjct: 901  KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960

Query: 624  KAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDS 669
            KAK+PE   +T  ++  ++   + EP  + +A        T  +DS
Sbjct: 961  KAKKPEEKPKTEAKAKEDDKTLSKEPS-KPKAEKAEKSSSTDQKDS 1005


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 79/355 (22%), Positives = 128/355 (36%), Gaps = 53/355 (14%)

Query: 321  PRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDI 380
            P A  E++ E +G ++P                 EA   AQ     G ++P     ++  
Sbjct: 1838 PEAEGEAQPESEGVEAP-----------------EAEGDAQE--AEGEAQPESEDVEAPE 1878

Query: 381  STLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSP-TESPHS--TPLL 437
            +     P S D+E  E   EV        QP +    + +A   + P TES  +  T   
Sbjct: 1879 AEGEAQPESEDVETPEAEWEV--------QPESEGAEAPEAEKEAQPETESVEALETEGE 1930

Query: 438  SSPDSE--QRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEP 495
              P+SE  + Q  E +      Q+   S V+  Q       + +  + E L  +  T E 
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEA-QPESEDVEALEVEVETQEA 1989

Query: 496  VLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDS 555
                   +E       +    +        S G+ +  KSEG+E   V +   Q  EGD+
Sbjct: 1990 EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV-EGETQKTEGDA 2048

Query: 556  E-----TKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLD 610
            +      +APE  +E+  +  EG   E   E H          ++ +D+   E       
Sbjct: 2049 QPESDGVEAPE--AEEEAQEAEGEVQEAEGEAHPE--------SEDVDAQEAEGEAQPES 2098

Query: 611  RSCGVPEESASSEKA---KEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHE 662
                 PE    ++KA   + PET  +   ES   E     E + Q E+ G  A +
Sbjct: 2099 EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE-APEAEGEAQPESEGVEAQD 2152


>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
          Length = 410

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 9/100 (9%)

Query: 38  IQRLKLE-------ATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIR 90
           I  LKLE        TL  H+G V  + W+     + SG+ D  +++ +   RK  T + 
Sbjct: 179 ITLLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLL 238

Query: 91  SGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAE 130
            GH   + S  +L  T  +Q+VSCS DG I   N++   E
Sbjct: 239 QGHHDKVQSLCYLQLT--RQLVSCSSDGGIAVWNMDVSRE 276


>gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
           sapiens]
          Length = 417

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 51/275 (18%)

Query: 411 PSTSSTMSAQAHSTSSPTESPH---STPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN 467
           PS +   +     T  P   P    S P+ ++   E   S EA+      ++ S SS   
Sbjct: 160 PSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSE 219

Query: 468 KQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSI----- 522
            ++ S+S  + +  + + +  +   G  V  L +  EG    T     + E SS+     
Sbjct: 220 SEVSSVSPLKNKHPDEDAVEAE---GHEVKRLRFDKEGEVRETASQTTSSEISSVMVGET 276

Query: 523 -ASSS--------RGIGSHCKSEGQEES-------------FVPQSSVQPPEGDSETKAP 560
            ASSS        R    HC  E +EE               +P+   Q  E D      
Sbjct: 277 EASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVN 336

Query: 561 EESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRS---CGVPE 617
           EE+SE+  + +E            +++Q++    K L  + G  N+  +  S   C   E
Sbjct: 337 EETSEENNQMEES-----------DVSQAE----KDLLHSEGSENEGPVSSSSSDCRETE 381

Query: 618 ESASSEKAKEPETSDQTSTESATNENNTNPEPQFQ 652
           E   S  +K  E   ++S E+         EP  Q
Sbjct: 382 ELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 75/333 (22%), Positives = 113/333 (33%), Gaps = 44/333 (13%)

Query: 371 PRGGTS-QSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSS--------TMSAQA 421
           P G T+ Q + +T  + PSS D     T     T    F++PST+S        T    A
Sbjct: 251 PAGSTTRQGESTTFHSWPSSKD-----TRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 305

Query: 422 HSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDN 481
            ST+S      ST   SSP S Q      S   +    +S +S                +
Sbjct: 306 RSTTSGLVE-ESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS--------------HSS 350

Query: 482 NNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEES 541
               +S  P T   ++    S   +  ST   +F D  ++   S     SH   +     
Sbjct: 351 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI 410

Query: 542 FVP-QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSN 600
            +P +S+     G+S T      S + T      +     E       S +  A  L   
Sbjct: 411 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA 470

Query: 601 SGERNDLNLDRSCGVPEESASSE----KAKEPETSDQTSTESATNENNTNPEPQFQTEAT 656
           S          S GV EES +S             D T+T   +  + T+      T+ T
Sbjct: 471 S--------TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 522

Query: 657 GPSAHEETS--TRDSALQDTDDSDDDPVLIPGA 687
              A   TS  +++S    +     D  L PG+
Sbjct: 523 LLPASTTTSGPSQESTTSHSSSGSTDTALSPGS 555



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 82/357 (22%), Positives = 127/357 (35%), Gaps = 56/357 (15%)

Query: 367  GRSRP-RGGTSQSDISTLPTVPSSPDL-EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST 424
            G S P R   S ++ +TLP  P++P L E S T        +  L P+T+++      S+
Sbjct: 897  GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 956

Query: 425  SSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNE 484
            +S ++ P ST   + PDS     +      +H    S  + ++    + S   QQ     
Sbjct: 957  TSHSQ-PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT-- 1013

Query: 485  KLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGI--GSHCKSEGQEESF 542
                 PG  E  L      + T TS +    T   SS  S    +   S   +  QEES 
Sbjct: 1014 -FHSSPGDTETTL----LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 1068

Query: 543  V----PQSSVQPPEGDSETKAPEE---------SSEDVTKYQEGVSAENPVENHINITQS 589
                 P SS   P     T AP E         SS   T +    +     E    +  S
Sbjct: 1069 TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 1128

Query: 590  -------------------DKFTAKPLDSNSGERNDL-NLDRSCGVPEESA---SSEKAK 626
                                + T  P+ S S E   L     + G+ E+S    SS ++ 
Sbjct: 1129 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 1188

Query: 627  EPETSDQTSTESATNENNTNPEPQ--------FQTEATGPSAHEETSTRDSALQDTD 675
            +   S  ++T S  +E +T    +        F    T P   +E++   S+   TD
Sbjct: 1189 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 1245



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/331 (21%), Positives = 111/331 (33%), Gaps = 38/331 (11%)

Query: 369 SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
           +R    T     +  P   +SP L+   TA +   PA     PS  ST +A    +++  
Sbjct: 594 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH-PASTHTTPSPPSTATAPVEESTTYH 652

Query: 429 ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSD----SPSSVVNKQLG-SMSLDEQQDNNN 483
            SP STP    P S             H   D    +PSS  +   G   S   +    +
Sbjct: 653 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 712

Query: 484 EKLSPKPG-TGEPVLS----LHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSE-- 536
            +++  PG T  P LS      YS+  + T+T+        S  + +S G+G    +   
Sbjct: 713 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL--------SPASMTSLGVGEESTTSRS 764

Query: 537 --GQEESFVPQSSVQPP-------------EGDSETKA-PEESSEDVTKYQEGVSAENPV 580
             G   S V  +S   P              G +ET   P  ++  V   +       P 
Sbjct: 765 QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPA 824

Query: 581 ENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESAT 640
             H  +   D  T   L   S            G+P    +++  +E  T   +S  + T
Sbjct: 825 STHTTLFTEDS-TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 883

Query: 641 NENNTNPEPQFQTEATGPSAHEETSTRDSAL 671
             +            + PS    +ST  + L
Sbjct: 884 KLSPARSTTSGLVGESTPSRLSPSSTETTTL 914



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 66/444 (14%)

Query: 237  TTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPS-- 294
            T+G+V    PS L+  S   T+L  S     +    ++ Y     P D T     T S  
Sbjct: 892  TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP-DATLSPATTTSSG 950

Query: 295  -AEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWF 353
             +EE      QP             T   A P+S    D  Q P  S   + S   +   
Sbjct: 951  VSEESSTSHSQP-----------GSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT--L 997

Query: 354  EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQ------ 407
               S  A S    G+      +S  D  T       PD  ++   +E  TP         
Sbjct: 998  SPGSTTASS---LGQQSTTFHSSPGDTET----TLLPDDTITSGLVEASTPTHSSTGSLH 1050

Query: 408  -FLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV 466
              L P++S++   Q  ST+  +  P S+    SP       VE S   T+H   S +   
Sbjct: 1051 TTLTPASSTSAGLQEESTTFQS-WPSSSDTTPSPPGTTAAPVEVS--TTYHSRPSSTPTT 1107

Query: 467  NKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSS 526
            +    S +L   +++     SP   TG  +    + T   T+  +    T   SS ++ +
Sbjct: 1108 HFSASSTTLGRSEESTTVHSSP-GATGTAL----FPTRSATSVLVGEPTTSPISSGSTET 1162

Query: 527  RGI-GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHIN 585
              + GS   +   E+S    SS + P+    T +P  ++      +   S   P   H  
Sbjct: 1163 TALPGSTTTAGLSEKSTTFYSSPRSPD---TTLSPASTTSSGVSEESTTSHSRPGSTH-- 1217

Query: 586  ITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNT 645
             T     T  P                 GV +ES +S  +  P ++D T +  +T  ++ 
Sbjct: 1218 TTAFPGSTTMP-----------------GVSQESTASHSS--PGSTDTTLSPGSTTASSL 1258

Query: 646  NPEPQFQTEATGPSAHEETSTRDS 669
             PE    T  + P + E T   D+
Sbjct: 1259 GPES--TTFHSSPGSTETTLLPDN 1280



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 66/299 (22%), Positives = 106/299 (35%), Gaps = 34/299 (11%)

Query: 384 PTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSE 443
           P    SP    S    E  T +    +P ++ T +A   ST++P  S HST   SSP S 
Sbjct: 463 PATTLSPASTTSSGVSEESTTSRS--RPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGST 519

Query: 444 QRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGT----GEPVLSL 499
               + AS   +    +S +S                + +  LSP   T    G+   + 
Sbjct: 520 DTTLLPASTTTSGPSQESTTS-----------HSSSGSTDTALSPGSTTALSFGQESTTF 568

Query: 500 HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
           H S  G+T +T+  + T     + +S+R    H  +     +  P SS  P      T  
Sbjct: 569 H-SNPGSTHTTLFPDSTTSSGIVEASTR---VHSSTGSPRTTLSPASSTSPGLQGESTAF 624

Query: 560 PEESSEDVTKYQEGVSAENPVENHINI------TQSDKFTAKPLDSNSGERNDL---NLD 610
               +   T      +A  PVE           T +  F A    S   E++ +   + D
Sbjct: 625 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 684

Query: 611 RSCGVPEESASSEKAKEPETSDQT---STESATNENNTNPEPQFQTEATGPSAHEETST 666
            S   P  + S+   +   T+ +    STE  T   +T      +   T  S+    +T
Sbjct: 685 ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 743



 Score = 33.5 bits (75), Expect = 0.89
 Identities = 50/297 (16%), Positives = 110/297 (37%), Gaps = 25/297 (8%)

Query: 369  SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT 428
            S  R G++ +  +  P   + P +    TA      +        S+T S+    +++  
Sbjct: 1209 SHSRPGSTHT--TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 1266

Query: 429  ESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVN-----KQLGSMSLDEQQDNNN 483
             SP ST     PD+     +  +    H  + SP + ++      + G  +  +   ++ 
Sbjct: 1267 SSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSK 1326

Query: 484  EKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFV 543
            + +   P T    + L  ++ G+ +ST   +F+   +++  S      H        +  
Sbjct: 1327 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1386

Query: 544  PQSSV-----------QPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKF 592
            P  S                G ++T    ESS    + +E  ++ +   + I+   S   
Sbjct: 1387 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST-- 1444

Query: 593  TAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEP 649
            T+  ++  +   +      +   PE S +S +++E      T++ S+ + N   P P
Sbjct: 1445 TSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEE-----STASHSSPDTNGITPLP 1496



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 61/303 (20%), Positives = 98/303 (32%), Gaps = 57/303 (18%)

Query: 412 STSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVV----- 466
           S  ST SA     +S   SP ST     PDS            +H   D+  ++V     
Sbjct: 357 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 416

Query: 467 --NKQLGSMSLDEQQDNNNEKL-----SPKPGTGEPVLSLH------------------- 500
             +  LG  +       + E       +  PG  E   + H                   
Sbjct: 417 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSG 476

Query: 501 YSTEGTTT-----STIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQS-SVQPPEGD 554
            S E TT+     ST    F D  ++   S     SH      + + +P S +   P  +
Sbjct: 477 VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 536

Query: 555 SETKAPEESSEDVTKYQEGVSA-----------ENPVENHINITQSDKFTAKPLDSNSGE 603
           S T      S D        +A            NP   H  +      ++  +++++  
Sbjct: 537 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST-- 594

Query: 604 RNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEE 663
                +  S G P  + S   +  P    + ST   T+  +T+  P   + AT P   EE
Sbjct: 595 ----RVHSSTGSPRTTLSPASSTSPGLQGE-STAFQTHPASTHTTPSPPSTATAPV--EE 647

Query: 664 TST 666
           ++T
Sbjct: 648 STT 650



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 48/235 (20%), Positives = 87/235 (37%), Gaps = 21/235 (8%)

Query: 317  SDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSR--PRGG 374
            S T     PES        S   +L+    +  +    EAS    S+ G   +   P G 
Sbjct: 1252 STTASSLGPESTTFHSSPGSTETTLLP--DNTTASGLLEASTPVHSSTGSPHTTLSPAGS 1309

Query: 375  TS-QSDISTLPTVPSSPDL---EVSETAMEVDTPAEQFLQPSTSSTMSAQAHST----SS 426
            T+ Q + +T  + PSS D      + T+  V+        PS++ T    A ST    S 
Sbjct: 1310 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 1369

Query: 427  PTESPHSTPLLSSPDSEQRQSV------EASGHHTHHQSDSPSSVVNKQLGSMSLDEQQD 480
             + + HS+P+ ++      +S       E++ +H+   S            S   +E + 
Sbjct: 1370 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1429

Query: 481  NNN---EKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSH 532
            +++     +S  P T   ++    S   +  S    +F +  ++   S     SH
Sbjct: 1430 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASH 1484


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 5/80 (6%)

Query: 733 YKGHRNSRTMIKEANF--WGANFVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 790
           Y GH+N +  I  ANF   G  +++SGS+   ++IW+  T E +  L+    VV     H
Sbjct: 252 YTGHKNEKYCIF-ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310

Query: 791 PFDPILASSGIDYD--IKIW 808
           P + I+AS+ ++ D  IK+W
Sbjct: 311 PTENIIASAALENDKTIKLW 330



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/246 (23%), Positives = 94/246 (38%), Gaps = 34/246 (13%)

Query: 42  KLEATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAK 101
           K E T++ H   ++ + W+     ++S SDD  L I +  S K L T++ GH   +F   
Sbjct: 78  KFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-GHSNYVFCCN 136

Query: 102 FLPCTNDKQIVSCSGDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCG 161
           F P +N   IVS S D  +       D +T +  +    +      +    D    +S  
Sbjct: 137 FNPQSN--LIVSGSFDESVRI----WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190

Query: 162 EDGTVRWFDTRIKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDR 221
            DG  R +DT     C K    DD          S     P   Y+     D++++++D 
Sbjct: 191 YDGLCRIWDT-ASGQCLKTLIDDD------NPPVSFVKFSPNGKYILAATLDNTLKLWDY 243

Query: 222 RMLGTRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSD---YIY 278
                          + G   +    H N K C   +  +S  G + +VS S D   YI+
Sbjct: 244 ---------------SKGKCLKTYTGHKNEKYCIFAN--FSVTGGKWIVSGSEDNLVYIW 286

Query: 279 LFDPKD 284
               K+
Sbjct: 287 NLQTKE 292


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 5/80 (6%)

Query: 733 YKGHRNSRTMIKEANF--WGANFVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 790
           Y GH+N +  I  ANF   G  +++SGS+   ++IW+  T E +  L+    VV     H
Sbjct: 252 YTGHKNEKYCIF-ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310

Query: 791 PFDPILASSGIDYD--IKIW 808
           P + I+AS+ ++ D  IK+W
Sbjct: 311 PTENIIASAALENDKTIKLW 330



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/246 (23%), Positives = 94/246 (38%), Gaps = 34/246 (13%)

Query: 42  KLEATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAK 101
           K E T++ H   ++ + W+     ++S SDD  L I +  S K L T++ GH   +F   
Sbjct: 78  KFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-GHSNYVFCCN 136

Query: 102 FLPCTNDKQIVSCSGDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCG 161
           F P +N   IVS S D  +       D +T +  +    +      +    D    +S  
Sbjct: 137 FNPQSN--LIVSGSFDESVRI----WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190

Query: 162 EDGTVRWFDTRIKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDR 221
            DG  R +DT     C K    DD          S     P   Y+     D++++++D 
Sbjct: 191 YDGLCRIWDT-ASGQCLKTLIDDD------NPPVSFVKFSPNGKYILAATLDNTLKLWDY 243

Query: 222 RMLGTRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSD---YIY 278
                          + G   +    H N K C   +  +S  G + +VS S D   YI+
Sbjct: 244 ---------------SKGKCLKTYTGHKNEKYCIFAN--FSVTGGKWIVSGSEDNLVYIW 286

Query: 279 LFDPKD 284
               K+
Sbjct: 287 NLQTKE 292


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 89/344 (25%), Positives = 138/344 (40%), Gaps = 48/344 (13%)

Query: 369 SRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQP-STSSTMSAQAHSTSSP 427
           S P GGT  S       +P +  L+ S  A    T     L P +T    S+    ++  
Sbjct: 662 SSPPGGTKPSYTMVSSVIPETSSLQSS--AFREGTSLG--LTPLNTRHPFSSPEPDSAGH 717

Query: 428 TESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDS--------------PSSVVNKQLGSM 473
           T+   S PLLSS  S     V A+   +HH++ S              PSS V   L SM
Sbjct: 718 TKISTSIPLLSSA-SVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAV---LSSM 773

Query: 474 SLD------EQQDNNNEKLSPKPGTGEPVLS--LHYSTEGTTTSTIKLNFTDEWSSIASS 525
           +L       E+  N    L+    +GE      L  ST   TT +  ++ T   +S +S 
Sbjct: 774 TLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSE 833

Query: 526 SRGIGSHCKSEGQEESF---VPQSSVQPPEGDSETKA------PEESSEDVTKYQEGVSA 576
           S    S     G + +F    P + +     ++E  +      PE S   V       S 
Sbjct: 834 SPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSV 893

Query: 577 ENPVENHINI--TQSDKFTAKPLDSNSGERNDLNLDRSCG--VPEESASSEKAKEPETSD 632
             PV   ++   T+S +F++  L S     +  ++  S G  +P+ S  +  A   +T+ 
Sbjct: 894 PTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNR 953

Query: 633 QTSTESATNENNTNPE--PQFQTEATGPSAHEETSTRDSALQDT 674
            T  +SA  ++ T PE  P+F+T    PSA    ST  ++L  T
Sbjct: 954 DTFNDSAAPQSTTWPETSPRFKTGL--PSATTTVSTSATSLSAT 995



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 85/443 (19%), Positives = 158/443 (35%), Gaps = 63/443 (14%)

Query: 276  YIYLFDPKDDTARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQ 335
            YI   DPKD ++ ++ TP +           V+ LR   +   T                
Sbjct: 1324 YITTTDPKDTSSAQVSTPHS-----------VRTLRTTENHPKTESATPAAYSGSPKISS 1372

Query: 336  SPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVS 395
            SPN++     +  ++   E ++++  +      S     ++   +S +  +P+SP +  S
Sbjct: 1373 SPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVV--IPTSPTIGSS 1430

Query: 396  ETAMEVDTPAEQF-LQPSTSSTMS---AQAHSTS------------SPTESPHSTPLLSS 439
               +  D P E   L PS  +T++   A   STS            S   SP ST  +  
Sbjct: 1431 TLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFP 1490

Query: 440  PDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSL 499
            P S     +  S   T    ++ S+ +++ LG  SL    D     ++P   T   V+  
Sbjct: 1491 PMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEH 1550

Query: 500  HYSTEGTTTST-----IKLNFTDEWSSIASSSRG--------IGSHCKSEGQEESF---- 542
                + T ++T     +  +  D+ S  AS+S          +G+  +S  +  +F    
Sbjct: 1551 STQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPS 1610

Query: 543  ----------VPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKF 592
                       P +    P  D+ T     S   +      +   +P E   N+    + 
Sbjct: 1611 TDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRS 1670

Query: 593  TAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQ 652
            +   + S +G    L        P  S S    +      +++TE  T +++    P+  
Sbjct: 1671 STATV-SMAGTMGLL----VTSAPGRSISQSLGRVSSVLSESTTEGVT-DSSKGSSPRLN 1724

Query: 653  TEA-TGPSAHEETSTRDSALQDT 674
            T+  T  S+  E S  + +   T
Sbjct: 1725 TQGNTALSSSLEPSYAEGSQMST 1747



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 69/310 (22%), Positives = 112/310 (36%), Gaps = 21/310 (6%)

Query: 380  ISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSS 439
            +ST P V  S ++ ++     + T ++  L   TSST S +   +      PHS    ++
Sbjct: 5847 LSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEE--TT 5904

Query: 440  PDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSL 499
              S   + V      +  ++ SPSS V       ++       +      P +  PV SL
Sbjct: 5905 TMSRSTKGVSWQSPPSVEETSSPSSPVPLP----AITSHSSLYSAVSGSSPTSALPVTSL 5960

Query: 500  HYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKA 559
              S    T   +  +     SS+ S+S   G    SE    +     ++   E  +ET  
Sbjct: 5961 LTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNT----ETIHFSENTAETNM 6016

Query: 560  PEESSEDVTKYQEGVSAENPVENHI--NITQSDKFTAKPLDSNSGERNDLNLDRSCGVPE 617
               +S  + K    VS  +    H    +T S    A    S  G     N+DR      
Sbjct: 6017 GTTNS--MHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRD----S 6070

Query: 618  ESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDS 677
             S  + + KE  T+      ++T E+NT         AT  S  E T    + +  +  S
Sbjct: 6071 TSPLTPELKEDSTA---LVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQS 6127

Query: 678  DDDPVLIPGA 687
               P + P A
Sbjct: 6128 TKSPDISPEA 6137



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 71/354 (20%), Positives = 121/354 (34%), Gaps = 21/354 (5%)

Query: 344  RMSDMLSR------WFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSET 397
            +M+ ++SR      W    S    S+     S P   +S    STLP    S  L V+  
Sbjct: 9118 QMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSL 9177

Query: 398  AMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGH-HTH 456
                     + L  S+    S+  + +S+  E    T + +  +  +  +V  SG+ H  
Sbjct: 9178 LTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHES 9237

Query: 457  HQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFT 516
              S    SV  K   SM +     + N  L+  P   +       S    T   ++ + +
Sbjct: 9238 PSSVLADSVTTKATSSMGITYPTGDTN-VLTSTPAFSDTSRIQTKSKLSLTPGLMETSIS 9296

Query: 517  DEWSSIASSSRGIGS---HCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEG 573
            +E SS    S  + S      +E      +  S    P     T + + S E +T+    
Sbjct: 9297 EETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTP 9356

Query: 574  VSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQ 633
            ++ +   +  I        T K   S +  +    LD S         S   +    S  
Sbjct: 9357 LTRKESTDMAI--------TPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVV 9408

Query: 634  TSTESATNENNTNPEPQFQTEATGPSAHEETS--TRDSALQDTDDSDDDPVLIP 685
            T+  S   E+ + P P    + + PS+   +S  T  S L  T         +P
Sbjct: 9409 TTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVP 9462



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 79/347 (22%), Positives = 129/347 (37%), Gaps = 44/347 (12%)

Query: 376   SQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPT--ESPHS 433
             S S++ T+P+  +SP+ E S       +P    +  S   T S +  S + PT  ESPH 
Sbjct: 11285 SHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSL-VTSSGRDISATFPTVPESPHE 11343

Query: 434   TPLLSS----PDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPK 489
             +   +S    P          + +++H + D+  S+      + S   +  ++   ++  
Sbjct: 11344 SEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSI------ATSPGAEATSDFPTITVS 11397

Query: 490   PGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQ 549
             P   + V S   ++ GT TS      T       +++  I     SE    S +P   V 
Sbjct: 11398 PDVPDMVTS-QVTSSGTDTSITIPTLTLSSGEPETTTSFI---TYSETHTSSAIPTLPVS 11453

Query: 550   PPEGDSETKAPEESSEDVTKYQEGVSAENPVENH------INITQSDKFTAKPLDSNSGE 603
             P      T     S  D T     ++ E P E        I+  +++    +     S  
Sbjct: 11454 PGASKMLTSLVISSGTDSTTTFPTLT-ETPYEPETTAIQLIHPAETNTMVPRTTPKFSHS 11512

Query: 604   RNDLNLD---RSCGVPEESASSEKAKEPETSDQTST---ESATNENNTNP-------EPQ 650
             ++D  L     S G    SA S     P+ SD  ++    S T+ + T P       EP 
Sbjct: 11513 KSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEP- 11571

Query: 651   FQTEATGPSAHEETSTRDSAL-----QDTDDSDDDPVLIPGARYRAG 692
              +T AT  +   ETST  S           D+    V  PG   R+G
Sbjct: 11572 -ETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSG 11617



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 74/362 (20%), Positives = 128/362 (35%), Gaps = 47/362 (12%)

Query: 354  EEASEVAQSNRGRGRSRPRGGTSQSDIS----TLPTVPSSPDLEV-SETAMEVDTPAEQF 408
            E  S +    +     +    T++S+I     ++  +  +  +EV S  A  + TPA+  
Sbjct: 4594 EPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQST 4653

Query: 409  LQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNK 468
              P   S  S++  ++   T S H T   +       +   A    T   S    SVV +
Sbjct: 4654 KFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTE 4713

Query: 469  QLGSMSLDEQQDNNNEKLS----------PKPGTGEPVLSLHYSTEGTTTSTIKLNFTDE 518
                  +    +N+ + +S            P +  PVL         TT    + FT +
Sbjct: 4714 GFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVL--------VTTLPSSVAFTPQ 4765

Query: 519  WSSIAS----SSRGIGSHCKSEGQEESFV------PQSSVQPPEGDSETKAPEESSEDV- 567
            W S +S    SS    S  K+ G+ ++ +      PQS     +  S T A     E   
Sbjct: 4766 WHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTH 4825

Query: 568  ----TKYQEGVSAENPVENHINIT--------QSDKFTAKPLDSNSGERNDLNLDRSCGV 615
                T      +  +  E+H  ++         S   T   ++  +  R+     ++   
Sbjct: 4826 PSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRT 4885

Query: 616  PEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTD 675
              E+ SS   K  ETS      S+T E +T P  +     T  S  + TS+  ++    D
Sbjct: 4886 ETETTSSLTPKLRETSISQEITSST-ETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPD 4944

Query: 676  DS 677
             S
Sbjct: 4945 QS 4946



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 60/280 (21%), Positives = 102/280 (36%), Gaps = 40/280 (14%)

Query: 412  STSSTMSAQAHSTSSPTESPH-----------STPLLSSPDSEQRQSVEASGHHTHHQSD 460
            ST+ST+   + STS+P  S             S  L  S  SE+  S   +     +   
Sbjct: 5454 STTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPT 5513

Query: 461  SPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWS 520
               +  ++   S S     D +   ++P   TG   +     T    T + ++  T + +
Sbjct: 5514 GAITQASRTEISSSRTSISDLDRPTIAPDISTG---MITRLFTSPIMTKSAEMTVTTQTT 5570

Query: 521  SIASSSRGI------------GSHCK-SEGQEESFVPQSSVQPPEGDSETKAP--EESSE 565
            +  ++S+GI            G+H   S+G   S +     + P   S    P  EE+S 
Sbjct: 5571 TPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSS 5630

Query: 566  DVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKA 625
              +     +++ +PV +    T  +   + PL   +       L  S  V   +     +
Sbjct: 5631 GFSLMSPSMTSPSPVSS----TSPESIPSSPLPVTA-------LLTSVLVTTTNVLGTTS 5679

Query: 626  KEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETS 665
             EP TS   +  S T E  T  +    TEA   S H  T+
Sbjct: 5680 PEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTA 5719



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 40/187 (21%), Positives = 71/187 (37%), Gaps = 33/187 (17%)

Query: 378   SDISTLPTVPSSPDLEVSETAMEVDTPAE-QFLQPSTSSTMSAQAHSTSSPT--ESPHST 434
             S++ T+ +  +S   +VS       +P+E   L P    T+S    ST+ PT  +SPH T
Sbjct: 10620 SELDTVSSTATSHGADVSSAIPTNISPSELDALTPLV--TISGTDTSTTFPTLTKSPHET 10677

Query: 435   PL----LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKP 490
                   L+ P            + +HH+SD+  S+                       + 
Sbjct: 10678 ETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSP-----------------GAET 10720

Query: 491   GTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSH-------CKSEGQEESFV 543
              +  P++++    E   TS +  + TD   +I + +   G            E Q  S +
Sbjct: 10721 SSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAI 10780

Query: 544   PQSSVQP 550
             P S++ P
Sbjct: 10781 PTSTISP 10787



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 61/286 (21%), Positives = 110/286 (38%), Gaps = 40/286 (13%)

Query: 385  TVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDS-- 442
            T+P  P +E +  +  +  P+     P  SST+    H+T SP  S  +  L+ + D+  
Sbjct: 6791 TIP--PSIEKTSFSSSL-MPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLG 6847

Query: 443  ---EQRQSVEASGHHTHHQ---SDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPV 496
               E   S   +   T H+   +D  ++ +     S S       N E  S   G+   V
Sbjct: 6848 TSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTS---TAATNVETTSSGHGSQSSV 6904

Query: 497  LSLHYSTEGT----TTSTIKLNFTDEWSSIASSSRGI----------GSHCKSEGQEESF 542
            L+    T+ T    TTST+         S++S +  I          G    S  Q  SF
Sbjct: 6905 LADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASF 6964

Query: 543  VPQSSVQPPEGDSETKAPEESSEDVTKYQEGV--SAENPVENHINITQSDKFTAKPLDSN 600
               +S+   E  + T A    +E  +  +  +   +++ V   I+     +  A P  + 
Sbjct: 6965 STDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTE 7024

Query: 601  SGERNDLNLDRSCGVPEESA-SSEKAKEPETSDQTSTESATNENNT 645
            S E           +P ++  S   +++  T D ++T+S    ++T
Sbjct: 7025 SAEMT---------IPTQTGPSGSTSQDTLTLDTSTTKSQAKTHST 7061



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 39/213 (18%)

Query: 381   STLPTVPSSPDLE--------------------VSETAMEVDTPAEQFLQPSTSSTMSAQ 420
             S +PT+P SP                       ++ET  E +T A Q + P+ ++TM  +
Sbjct: 11445 SAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPR 11504

Query: 421   AHSTSSPTESPHSTPL-LSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSMSLDEQQ 479
                  S ++S  + P+ ++SP  E   +V      T   S   S +V   + S   D   
Sbjct: 11505 TTPKFSHSKSDTTLPVAITSPGPEASSAVS-----TTTISPDMSDLVTSLVPSSGTDTST 11559

Query: 480   DNNNEKLSP-KPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASS---SRGIGSHCKS 535
                    +P +P T    L+    T  T + TI  NF+   S  A S   S G+ +    
Sbjct: 11560 TFPTLSETPYEPETTATWLTHPAETSTTVSGTIP-NFSHRGSDTAPSMVTSPGVDT---- 11614

Query: 536   EGQEESFVPQSSVQPPEGDSETKAPEESSEDVT 568
                  S VP +++ P      T     S+ D +
Sbjct: 11615 ----RSGVPTTTIPPSIPGVVTSQVTSSATDTS 11643



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 62/270 (22%), Positives = 104/270 (38%), Gaps = 40/270 (14%)

Query: 400  EVDTPAEQFLQPSTSSTMSA-QAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQ 458
            E  +P+     P+ +S  S   A S SSPT +   T LL+S    +R++++    H+   
Sbjct: 5923 ETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSG---RRKTIDMLDTHSELV 5979

Query: 459  SDSPSSVVNKQLGSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDE 518
            + S  S          L  +   N E +     T E       +  GTT S  KL+    
Sbjct: 5980 TSSLPSA--SSFSGEILTSEASTNTETIHFSENTAE-------TNMGTTNSMHKLH---- 6026

Query: 519  WSSIASSSRGIGS---HCKSEGQEESFVPQSSVQPPEG-----DSETKAPEESSEDVTKY 570
             SS++  S+  G           E++ V  S+   PE      DS +    E  ED T  
Sbjct: 6027 -SSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTAL 6085

Query: 571  QEGVSAENPVENHINITQSDKFTAKPLDSNSG-ERNDLNLDRSCGVPEESASSEKAKEPE 629
                + E+          +  F++  LD+ +   R ++       +P   AS++  K P+
Sbjct: 6086 VMNSTTES----------NTVFSSVSLDAATEVSRAEVTYYDPTFMP---ASAQSTKSPD 6132

Query: 630  TSDQTSTESATNENNTNPEPQFQTEATGPS 659
             S + S+  + +   T    +     TGPS
Sbjct: 6133 ISPEASSSHSNSPPLTISTHKTIATQTGPS 6162


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 84/404 (20%), Positives = 147/404 (36%), Gaps = 53/404 (13%)

Query: 283 KDDTARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPR--ARPESERERDGEQ----- 335
           +D++  E      EE REELR+     +  + +   T  +  A+PE+++E+D E      
Sbjct: 124 EDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGR 183

Query: 336 -----SPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSP 390
                S +    Q   D+   W  E SE A     +G + P G  +++++++       P
Sbjct: 184 EDMDISKSAEEPQEKVDLTLDWLTETSEEA-----KGGAAPEG-PNEAEVTSGKPEQEVP 237

Query: 391 DLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEA 450
           D E  ++    D   E   +                P E     P+++         VEA
Sbjct: 238 DAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEA 297

Query: 451 SGHHTHHQSDSPSSVVNKQLGSMSLDEQ---QDNNNEKLSPKPGTGEPVLSLHYSTEGTT 507
                  +S  P+ V    +G    +E+    +N   K   +   G+ V     S E TT
Sbjct: 298 -------ESLDPT-VKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTT 349

Query: 508 TSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQS-SVQPPE--GDSETKAPEESS 564
            +        E S++ + S       +  GQE   +P+  +V  P   GD     P+ S 
Sbjct: 350 EAA-------EASAVEAGSEV----SEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSI 398

Query: 565 EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEK 624
           E +T+ ++G   E  V   +  +Q +   +      +G+          GV  + A    
Sbjct: 399 ERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGD----------GVDTKVAQGAT 448

Query: 625 AKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRD 668
            K PE   Q +    T E     +   +TE +     E   T +
Sbjct: 449 EKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 492



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 5/145 (3%)

Query: 530 GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQ-EGVSAENPVENHINITQ 588
           G H + E  E++     S+     + + +A EE  E V     E   A+   +  +   +
Sbjct: 112 GVHVEEEEGEKT--EDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPE 169

Query: 589 SDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPE 648
           +DK   +  +   G R D+++ +S   P+E          ETS++    +A    N    
Sbjct: 170 TDK--EQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEV 227

Query: 649 PQFQTEATGPSAHEETSTRDSALQD 673
              + E   P A EE S   + +Q+
Sbjct: 228 TSGKPEQEVPDAEEEKSVSGTDVQE 252


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 84/404 (20%), Positives = 147/404 (36%), Gaps = 53/404 (13%)

Query: 283 KDDTARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPR--ARPESERERDGEQ----- 335
           +D++  E      EE REELR+     +  + +   T  +  A+PE+++E+D E      
Sbjct: 126 EDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGR 185

Query: 336 -----SPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSP 390
                S +    Q   D+   W  E SE A     +G + P G  +++++++       P
Sbjct: 186 EDMDISKSAEEPQEKVDLTLDWLTETSEEA-----KGGAAPEG-PNEAEVTSGKPEQEVP 239

Query: 391 DLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEA 450
           D E  ++    D   E   +                P E     P+++         VEA
Sbjct: 240 DAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEA 299

Query: 451 SGHHTHHQSDSPSSVVNKQLGSMSLDEQ---QDNNNEKLSPKPGTGEPVLSLHYSTEGTT 507
                  +S  P+ V    +G    +E+    +N   K   +   G+ V     S E TT
Sbjct: 300 -------ESLDPT-VKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTT 351

Query: 508 TSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQS-SVQPPE--GDSETKAPEESS 564
            +        E S++ + S       +  GQE   +P+  +V  P   GD     P+ S 
Sbjct: 352 EAA-------EASAVEAGSEV----SEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSI 400

Query: 565 EDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEK 624
           E +T+ ++G   E  V   +  +Q +   +      +G+          GV  + A    
Sbjct: 401 ERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGD----------GVDTKVAQGAT 450

Query: 625 AKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRD 668
            K PE   Q +    T E     +   +TE +     E   T +
Sbjct: 451 EKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 494



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 5/145 (3%)

Query: 530 GSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQ-EGVSAENPVENHINITQ 588
           G H + E  E++     S+     + + +A EE  E V     E   A+   +  +   +
Sbjct: 114 GVHVEEEEGEKT--EDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPE 171

Query: 589 SDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPE 648
           +DK   +  +   G R D+++ +S   P+E          ETS++    +A    N    
Sbjct: 172 TDK--EQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEV 229

Query: 649 PQFQTEATGPSAHEETSTRDSALQD 673
              + E   P A EE S   + +Q+
Sbjct: 230 TSGKPEQEVPDAEEEKSVSGTDVQE 254


>gi|4557467 excision repair cross-complementing rodent repair
           deficiency, complementation group 8 isoform 1 [Homo
           sapiens]
          Length = 396

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 33/270 (12%)

Query: 17  RSLGLEDPSRLRSRYLGRREFIQRLKLEATL-NVHDGCVNTICWNDT-GEYILSGSDDTK 74
           R  GLEDP RLR     RR     L  +  +  +H G +NT+      G Y+LSG  D  
Sbjct: 8   RQTGLEDPLRLRRAESTRRVLGLELNKDRDVERIHGGGINTLDIEPVEGRYMLSGGSDGV 67

Query: 75  LVI--------SNPYSRKVLTTIRSG----HRANIFSAKFLPCTNDKQIVSCSGDGV--I 120
           +V+         + Y+ K + +I       HR ++ + ++ P  +     S S D    +
Sbjct: 68  IVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYP-HDTGMFTSSSFDKTLKV 126

Query: 121 FYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKE 180
           + TN  Q A+      F          M+  +  +  ++ G  G       +++    K 
Sbjct: 127 WDTNTLQTADV-----FNFEETVYSHHMSPVSTKHCLVAVGTRG------PKVQLCDLKS 175

Query: 181 DCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYD-RRMLGTRATGNYAGRGTTG 239
                IL   R+   +V+  P   Y LA   +DS V+++D RR  G   T +       G
Sbjct: 176 GSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLDQ----HNG 231

Query: 240 MVARFIPSHLNNKSCRVTSLCYSEDGQEIL 269
             ++ + S     + +V  LC++ DG  +L
Sbjct: 232 KKSQAVESANTAHNGKVNGLCFTSDGLHLL 261


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 54/248 (21%), Positives = 91/248 (36%), Gaps = 31/248 (12%)

Query: 471 GSMSLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIG 530
           G++++DE QDN   KL      G    SLH ST  +T   + L+  D    +  +     
Sbjct: 634 GAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKE--- 690

Query: 531 SHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSD 590
                  +EE  + Q +   P+  +E+K PEE  E+  K         PV +     + D
Sbjct: 691 -------KEEESLNQGARAQPQAKAESK-PEE--EEPAKLPAVTVTPAPVPD----IKGD 736

Query: 591 KFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQ 650
           +        N G + D+          ES      +E ET+ +  TE  +    T PE +
Sbjct: 737 Q------KENPGGQEDV-------AEAESTGEMPGEEGETAGEGETEEKSG-GETQPEGE 782

Query: 651 FQTEATGPSAHEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRR 710
            +TE  G     E         D +  D+  +       +   G+  S     +     +
Sbjct: 783 GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAK 842

Query: 711 KERKEMEE 718
            + K +E+
Sbjct: 843 NDEKGVED 850



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 29/126 (23%), Positives = 44/126 (34%), Gaps = 14/126 (11%)

Query: 524 SSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENH 583
           + ++G G  C+ E + E           EG+ E +   E  E      E  S E   ENH
Sbjct: 785 TETQGKGEECEDENEAEGKGDN------EGEDEGEIHAEDGEMKGNEGETESQELSAENH 838

Query: 584 INITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNEN 643
                 +K       S+ G+  +          EE    E+ +E E  ++   E    E 
Sbjct: 839 GEAKNDEKGVEDGGGSDGGDSEE--------EEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890

Query: 644 NTNPEP 649
             N EP
Sbjct: 891 KGNEEP 896


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 5/80 (6%)

Query: 733 YKGHRNSRTMIKEANF--WGANFVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPH 790
           Y GH+N +  I  ANF   G  +++SGS+   ++IW+  T E +  L+    VV     H
Sbjct: 248 YTGHKNEKYCIF-ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACH 306

Query: 791 PFDPILASSGIDYD--IKIW 808
           P + ++AS+ ++ D  IK+W
Sbjct: 307 PTENLIASAALENDKTIKLW 326



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 57/256 (22%), Positives = 95/256 (37%), Gaps = 54/256 (21%)

Query: 42  KLEATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAK 101
           K E TL  H+  ++ + W+     ++S SDD  L + +  S K L T++ GH   +F   
Sbjct: 74  KYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLK-GHSNYVFCCN 132

Query: 102 FLPCTNDKQIVSCSGDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYT----- 156
           F P +N   I+S S D  +    V+               G   + ++  +DP +     
Sbjct: 133 FNPPSN--LIISGSFDETVKIWEVKT--------------GKCLKTLSAHSDPVSAVHFN 176

Query: 157 -----FLSCGEDGTVRWFDTRIKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGC 211
                 +S   DG  R +D      C K    DD          S     P   Y+    
Sbjct: 177 CSGSLIVSGSYDGLCRIWDA-ASGQCLKTLVDDD------NPPVSFVKFSPNGKYILTAT 229

Query: 212 SDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVS 271
            D++++++D                + G   +    H N K C   +  +S  G + +VS
Sbjct: 230 LDNTLKLWDY---------------SRGRCLKTYTGHKNEKYCIFAN--FSVTGGKWIVS 272

Query: 272 YSSD---YIYLFDPKD 284
            S D   YI+    K+
Sbjct: 273 GSEDNLVYIWNLQTKE 288


>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
          Length = 400

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%)

Query: 43  LEATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKF 102
           L  T   H G V  +CW+     + SGS D  +++ +   RK       GH   + +  +
Sbjct: 191 LVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSY 250

Query: 103 LPCTNDKQIVSCSGDGVIFYTNVEQDAE 130
              T  +Q++SC GDG I   N++ + +
Sbjct: 251 AQHT--RQLISCGGDGGIVVWNMDVERQ 276


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,565,345
Number of Sequences: 37866
Number of extensions: 1797430
Number of successful extensions: 10246
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 8227
Number of HSP's gapped (non-prelim): 2361
length of query: 880
length of database: 18,247,518
effective HSP length: 111
effective length of query: 769
effective length of database: 14,044,392
effective search space: 10800137448
effective search space used: 10800137448
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press