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Search of human proteins with 63252906
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 528 e-150
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 499 e-142
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 479 e-135
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 450 e-127
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 434 e-122
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 417 e-117
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 404 e-113
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 401 e-112
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 379 e-105
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 375 e-104
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 330 1e-90
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 317 1e-86
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 315 2e-86
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 310 1e-84
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 308 3e-84
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 295 2e-80
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 291 4e-79
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 88 1e-17
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 85 8e-17
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 82 5e-16
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 82 5e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 82 5e-16
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 81 9e-16
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 81 9e-16
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 81 9e-16
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 81 9e-16
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 3e-15
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 79 3e-15
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 77 2e-14
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 77 2e-14
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 528 bits (1361), Expect = e-150
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 499 bits (1286), Expect = e-142
Identities = 268/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 479 bits (1232), Expect = e-135
Identities = 257/284 (90%), Positives = 268/284 (94%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 450 bits (1157), Expect = e-127
Identities = 241/284 (84%), Positives = 259/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 434 bits (1116), Expect = e-122
Identities = 235/284 (82%), Positives = 256/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 417 bits (1073), Expect = e-117
Identities = 218/284 (76%), Positives = 253/284 (89%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 404 bits (1037), Expect = e-113
Identities = 218/284 (76%), Positives = 247/284 (86%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 401 bits (1031), Expect = e-112
Identities = 211/282 (74%), Positives = 247/282 (87%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+EE++ +K L+ +EDE D+
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E+L A++ L E+ A+ AE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 379 bits (974), Expect = e-105
Identities = 202/284 (71%), Positives = 243/284 (85%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLE+++AA +K L+ +EDE D+
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ AA AEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 375 bits (962), Expect = e-104
Identities = 199/284 (70%), Positives = 239/284 (84%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + LEE+L+I+ LK+L A DKYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE++V K + ++ + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 330 bits (845), Expect = 1e-90
Identities = 173/242 (71%), Positives = 204/242 (84%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 283 NM 284
M
Sbjct: 247 EM 248
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 317 bits (811), Expect = 1e-86
Identities = 168/240 (70%), Positives = 198/240 (82%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ A ++ ++ + + D + + L E KAE DVA+LNRRIQLVEEELDRA
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YE
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/237 (22%), Positives = 99/237 (41%), Gaps = 70/237 (29%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++A+K+K+Q L+ + A DRA+ + + +R ++ E D+AA + +++ E+E DR
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 ----------LEELHKAEDS-------------------------LLAAEEAAAKAEADV 85
LEE KA D L A+ A +A+
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 86 ASLNRRIQLVEEELDR---------------------AQERLATALQKLEEAEKAADESE 124
+ R++ ++E EL+R + L+ LE A + E E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKN----VTNNLKSLEAASEKYSEKE 182
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
K EE++++ +LKEA+ AE A+R ++ + + +E L +A+E
Sbjct: 183 ----------DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKE 229
Score = 48.1 bits (113), Expect = 9e-06
Identities = 32/114 (28%), Positives = 57/114 (50%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ + +K+ +L+ + E A +RAE +E E+ K + ++ + E ++ D+
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
EE+ D L AE A AE VA L + I +EE+L +A+E Q L++
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Score = 38.1 bits (87), Expect = 0.009
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 8/142 (5%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
++KM++ ++ + A AE+A+ + + LE ++ E+ VSE + + EEL
Sbjct: 102 EEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++L + E A+ K + + EEE+ ++L A + E AE+ + E
Sbjct: 162 KNVTNNLKSLEAASEK-------YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE 214
Query: 125 RGMKVIESR-AQKDEEKMEIQE 145
+ + +E + AQ EE + + +
Sbjct: 215 KTIDDLEEKLAQAKEENVGLHQ 236
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 315 bits (808), Expect = 2e-86
Identities = 168/242 (69%), Positives = 199/242 (82%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 283 NM 284
M
Sbjct: 247 EM 248
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 310 bits (793), Expect = 1e-84
Identities = 165/239 (69%), Positives = 195/239 (81%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 28/181 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE---DER 57
+D ++++ E A A+++E K E+R+ + EE + +E L+ ++ +E
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Query: 58 DRVLEELHKA----EDSLLAAEEAAAKAEADVASLNRRIQLV------------------ 95
DR EE+ + E L EE A AE+ ++ +I+L+
Sbjct: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
Query: 96 ---EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
EEE+ ++L A + E AE++ + E+ + +E R E+ + +LK
Sbjct: 183 DKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTL 242
Query: 153 H 153
H
Sbjct: 243 H 243
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 308 bits (790), Expect = 3e-84
Identities = 171/238 (71%), Positives = 191/238 (80%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ A + +R +++ D E + L + AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 63.9 bits (154), Expect = 2e-10
Identities = 49/234 (20%), Positives = 104/234 (44%), Gaps = 35/234 (14%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++A+++K++ L+ + A +RA + + + E D+A+ + +++ E+E DR
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQ--------------------------- 93
E L A L AE+AA ++E + + R Q
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 94 --------LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE 145
++E +L+RA+ER + K E E+ +K +E++A+K +K + E
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 146 IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRI 199
++K ++A+ + E R + +E ++ E++ Q R+L +L++
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
Score = 38.5 bits (88), Expect = 0.007
Identities = 40/179 (22%), Positives = 77/179 (43%), Gaps = 28/179 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE---DER 57
+D ++++ E A A+++E K E R+++ EE + +E L+ ++ ++
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
Query: 58 DRVLEELHKA----EDSLLAAEEAAAKAEADVASLNRRIQLV------------------ 95
DR EE+ + E L AEE A +E A L ++ V
Sbjct: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
Query: 96 ---EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 151
EEE+ ++L A + E AE++ + E+ + +E + + E+ +LK A
Sbjct: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 295 bits (756), Expect = 2e-80
Identities = 160/239 (66%), Positives = 190/239 (79%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/149 (21%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
++KM++ ++ + A AE+A+ + + +E D+ E+ ++E + + EEL
Sbjct: 102 EEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 161
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++L + E A K +++ EEE+ ++L A + E AE++ + E
Sbjct: 162 KNVTNNLKSLEAQAEK-------YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+ + +E R E+ + +LK H
Sbjct: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 291 bits (745), Expect = 4e-79
Identities = 165/284 (58%), Positives = 204/284 (71%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+ DR++Q E D + ++R +
Sbjct: 1 MDAIKKKMQMLKLDKENAI--------------DRAEQAEAD--------KKQAEDRCKQ 38
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEE +A L ++++ E+E++ K E+EKAA
Sbjct: 39 LEEEQQA--------------------LQKKLKGTEDEVE-----------KYSESEKAA 67
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/277 (24%), Positives = 129/277 (46%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
+++ + +E L +A++ E K+ E QL+E++AA E+ R ++ ERD + +E+
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ A E + EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD----RKYE----EVARKLVIIESDLE 177
+ + S AQK+E + E Q KE K ++ + KY+ + K+ +E L+
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ + + QVR+ E++L+ + + ++Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
A+ A S KL++ ++D E E S+ L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 64.7 bits (156), Expect = 9e-11
Identities = 76/325 (23%), Positives = 146/325 (44%), Gaps = 44/325 (13%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLR--------VSED 55
++K + L+ E + E+ E + +A ED +LE ++ A + SE+
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT 108
++ +++ ++ + E L A A K E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADR----K 161
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R +
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 162 YEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR--------IMDQTLKALMA---- 209
+E+A ++ A E E ++ QLEE+L I D+ KA +
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQI 1762
Query: 210 -----AEDKYSQKED----RYEEEIKVLSDKLKEAE-TRAEFAERSVTKLEKSIDDLEEK 259
E ++QK + + E + K L KL+E E T + S+T LE I LEE+
Sbjct: 1763 NTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 260 VAHAKEENLSMHQMLDQTLLELNNM 284
+ + +E + + + +T +L ++
Sbjct: 1823 LDNETKERQAACKQVRRTEKKLKDV 1847
Score = 63.2 bits (152), Expect = 3e-10
Identities = 74/309 (23%), Positives = 145/309 (46%), Gaps = 47/309 (15%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV------ 60
K++ +L EN L E ++ A + QL+E + A+ +L +E+ R R+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEK---LQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 61 LEEL-HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQ--------ERLAT--A 109
LEE+ H E + EE +A+ + + IQ +EE+L+ + E++ T
Sbjct: 913 LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK 972
Query: 110 LQKLEEAEKAADESE----RGMKVIESR--------AQKDEEKMEIQEIQLKEAKHIAED 157
L+KLEE + ++ + K++E R +++E+ + +++ K I +
Sbjct: 973 LKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032
Query: 158 ADR---------KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALM 208
+R + E+ RKL +DL +++ AEL + Q+ +L+ QL ++ L+A +
Sbjct: 1033 EERLRREEKQRQELEKTRRKLEGDSTDL--SDQIAEL-QAQIAELKMQLAKKEEELQAAL 1089
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENL 268
A ++ + +++ ++I+ L ++ E + E S K EK DL E++ K E
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE-- 1147
Query: 269 SMHQMLDQT 277
+ LD T
Sbjct: 1148 -LEDTLDST 1155
Score = 63.2 bits (152), Expect = 3e-10
Identities = 68/307 (22%), Positives = 130/307 (42%), Gaps = 39/307 (12%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAE 75
E +R + +A+KK + ++LEE + +E + + E+ +L K E+ + E
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 76 EAAAKAEADVASLNRRI-----QLVEEE----------------LDRAQERLATALQKLE 114
+ K + L RI L EEE + +ERL ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 115 EAEKA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----R 160
E EK D ++ ++ E +AQ E KM++ +E+Q A+ E A +
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
K E+ ++ ++ DLE +E Q R L E+L + L+ + + + +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 221 YEEEIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMH---QMLDQ 276
E+E+ +L L +EA+T + K +++++L E++ K ++ Q L+
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 277 TLLELNN 283
EL N
Sbjct: 1225 ERGELAN 1231
Score = 63.2 bits (152), Expect = 3e-10
Identities = 57/304 (18%), Positives = 143/304 (47%), Gaps = 22/304 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
D ++K L+ + ++ L + E + K+ ++ +A ++ + +ERDR
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 62 EELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
E + E SL A E A + +A++ LN++ + E+L +++ + ++ +LE++++
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 119 AADESERGMKV----IESRAQKDEEKMEIQEIQL--------KEAKHIAEDADRKYEEVA 166
A ++ MK +E Q E+ E+ L ++ + E ++ K +++
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 167 RKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIK 226
R++ +E++LE ++ ++ ++LE L+ ++ + + D+ ++ + + ++K
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 227 VLSDKL-------KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
+L +E +A+ E+ + +E + L+E++A A+ Q D+
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 280 ELNN 283
E+ N
Sbjct: 1709 EIAN 1712
Score = 60.8 bits (146), Expect = 1e-09
Identities = 61/271 (22%), Positives = 122/271 (45%), Gaps = 20/271 (7%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAK---EKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
E + +A E+ ++QLE+ K EK + E+ER + E+ +E
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K EA + L Q+ E +R + LA + KL+ D + +S++ K +
Sbjct: 1249 KVEAQLQEL----QVKFNEGERVRTELADKVTKLQVE---LDNVTGLLSQSDSKSSKLTK 1301
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD-------LERAEERAELSEGQVRQ 192
E QL++ + + ++ +R+ ++ KL +E + LE EE E Q+
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKS 252
L Q+ M + ++ + + + + + +++++ LS + +E + E++ T+L++
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 253 IDDLEEKVAHAKEE--NLSMHQ-MLDQTLLE 280
+DDL + H ++ NL Q DQ L E
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAE 1452
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/255 (21%), Positives = 121/255 (47%), Gaps = 19/255 (7%)
Query: 36 SKQLEEDIAAKEKLLRVSEDE--RDRVLEELHKAEDSLLAA-----EEAAAKAE--ADVA 86
S+Q EE +A +E+L++V E + + L E+ + L+A E+ A+ E A+
Sbjct: 841 SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 900
Query: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 146
L R+ ++EL+ L ++EE E+ + K ++ Q+ EE++E +E
Sbjct: 901 ELRARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES 957
Query: 147 QLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKA 206
++ + + K +++ + +I+E + + +L E ++ + L ++ K+
Sbjct: 958 ARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 207 LMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
L ++ ++++E I L ++L+ E + + E++ KLE DL +++A + +
Sbjct: 1018 L-------AKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 267 NLSMHQMLDQTLLEL 281
+ L + EL
Sbjct: 1071 IAELKMQLAKKEEEL 1085
Score = 55.8 bits (133), Expect = 4e-08
Identities = 66/305 (21%), Positives = 130/305 (42%), Gaps = 59/305 (19%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEED----------IAAK 46
+ A KKKMQ + E L+ E A + +K E + K+LEE+ +A +
Sbjct: 934 LQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKE 993
Query: 47 EKLLR----------VSEDERDRVLEELHKAEDSLLA---------------AEEAAAKA 81
+KLL E+E+ + L +L ++++ E+ K
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 82 EAD-------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E D +A L +I ++ +L + +E L AL ++EE + + + ++ +ES+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
+ +E +E + +A+ D + E + +L E L+ + EL + E
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTEL---EDTLDSTAAQQELRS----KRE 1166
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
+++ I+ +TL E++ E + +E + S ++E + E +R LEK+
Sbjct: 1167 QEVNILKKTL------EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
Query: 255 DLEEK 259
LE +
Sbjct: 1221 TLENE 1225
Score = 55.1 bits (131), Expect = 7e-08
Identities = 65/281 (23%), Positives = 121/281 (43%), Gaps = 41/281 (14%)
Query: 19 LDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH-----KAEDSLLA 73
L + Q E E+ K E+ +AA+ +L + + + E+L +AE L A
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA 897
Query: 74 -AEEAAAK--------------AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
AEE A+ EA V R Q ++ E + Q+ + ++LEE E
Sbjct: 898 EAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES 957
Query: 119 AADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKY-------EEVARK 168
A + + E++ +K EE+ +E Q +L + K + ED ++ EE ++
Sbjct: 958 ARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 169 LVII----ESDLERAEERAELSEGQVRQLEEQLRIMD-------QTLKALMAAEDKYSQK 217
L + E+ + EER E Q ++LE+ R ++ + L A + +
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+ EEE++ +++E + A + + +LE I +L+E
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Score = 54.3 bits (129), Expect = 1e-07
Identities = 60/249 (24%), Positives = 113/249 (45%), Gaps = 13/249 (5%)
Query: 21 RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDS---LLAAEEA 77
+ +Q E +K + + QLEE+ AK L + +V + K EDS L AEE
Sbjct: 1330 KLKQVEDEKNSFRE---QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEV 1386
Query: 78 AAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD 137
K + D+ L++R + D+ ++ Q+L++ D + +E + +K
Sbjct: 1387 KRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKF 1446
Query: 138 EEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQL 197
++ + E + AK+ AE+ DR E AR+ L RA E A + ++ +L +Q
Sbjct: 1447 DQL--LAEEKTISAKY-AEERDRA-EAEAREKETKALSLARALEEAMEQKAELERLNKQF 1502
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
R ++ LM+++D + E+ + L +++E +T+ E E + E + LE
Sbjct: 1503 R---TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE 1559
Query: 258 EKVAHAKEE 266
+ K +
Sbjct: 1560 VNLQAMKAQ 1568
Score = 53.9 bits (128), Expect = 2e-07
Identities = 68/307 (22%), Positives = 123/307 (40%), Gaps = 38/307 (12%)
Query: 9 QMLKLDKENAL--DRAEQAEADKKAAEDRSKQL-------EEDIAAKEKLLRVSEDERDR 59
Q KL KE L DR + + E++SK L E I E+ LR E +R
Sbjct: 986 QNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQE 1045
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT-------ALQK 112
+ + K E + A+ +A +A L ++ EEEL A R+ AL+K
Sbjct: 1046 LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK 1105
Query: 113 LEEAEKAADESERGM---KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+ E E E + + + ++A+K + + + LK D+ +E+ K
Sbjct: 1106 IRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKR 1165
Query: 170 VIIESDLERA-EERAELSEGQVRQ-----------LEEQLRIMDQTLKALMAAEDKYSQK 217
+ L++ EE A+ E Q+++ L EQL + L A+ +
Sbjct: 1166 EQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENE 1225
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQT 277
E+KVL ++E + + K+E + +L+ K + + + +
Sbjct: 1226 RGELANEVKVLLQGKGDSEHKRK-------KVEAQLQELQVKFNEGERVRTELADKVTKL 1278
Query: 278 LLELNNM 284
+EL+N+
Sbjct: 1279 QVELDNV 1285
Score = 51.6 bits (122), Expect = 8e-07
Identities = 48/244 (19%), Positives = 115/244 (47%), Gaps = 17/244 (6%)
Query: 33 EDRSKQLEEDIAAKEKL---LRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLN 89
+D + L+E+ K L L+ EDE++ E+L + E++ E+ A A VA +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 90 RR-------IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
++ ++ EE + Q+ L Q+ EE A D+ E+ ++R Q++ + +
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK----TKTRLQQELDDLL 1426
Query: 143 IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
+ +++ E +K++++ + I + + AEER + +E + R+ E + + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISA--KYAEER-DRAEAEAREKETKALSLAR 1483
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
L+ M + + + ++ E++ L + E+S LE+ +++++ ++
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 263 AKEE 266
++E
Sbjct: 1544 LEDE 1547
Score = 45.8 bits (107), Expect = 4e-05
Identities = 40/197 (20%), Positives = 87/197 (44%), Gaps = 3/197 (1%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
++ ++ L+ + E E K A + Q+ D+ + + +E+ R + LE
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQ-LER 1785
Query: 64 LHKAEDSLLAAEEAAAKAE--ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+K L E K++ A + +L +I +EE+LD + A +++ EK
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ + A++ +++ + +LK+ K E+A+ + + ++ +LE A E
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Query: 182 RAELSEGQVRQLEEQLR 198
A+ +V L+ +LR
Sbjct: 1906 TADAMNREVSSLKNKLR 1922
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/181 (20%), Positives = 87/181 (48%), Gaps = 15/181 (8%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHK 66
K L++D+ N E++ A K E+ +QLE + K L+V E + ++ +K
Sbjct: 1753 KKANLQIDQINTDLNLERSHAQKN--ENARQQLER----QNKELKVKLQEMEGTVKSKYK 1806
Query: 67 AEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK-------A 119
A S+ A E A+ E + + + Q +++ R +++L L ++++ +
Sbjct: 1807 A--SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
AD++ +K ++ + ++ EE+ + ++ + EDA + + R++ +++ L R
Sbjct: 1865 ADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRG 1924
Query: 180 E 180
+
Sbjct: 1925 D 1925
Score = 29.6 bits (65), Expect = 3.1
Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMD-QTLKALMAAEDKYSQKE 218
R + +V L + + E + EL + + +QL + R+ + +TL++ + AE Q++
Sbjct: 829 RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+ E E+ +++L+ T + +LE+ DLE +V +EE H ++
Sbjct: 889 LQAETELCAEAEELRARLTAKK------QELEEICHDLEARV--EEEEERCQHLQAEKKK 940
Query: 279 LELN 282
++ N
Sbjct: 941 MQQN 944
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 84.7 bits (208), Expect = 8e-17
Identities = 55/255 (21%), Positives = 125/255 (49%), Gaps = 6/255 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + + +KE + R E+ +K E++ ++LEE + +EK + E E R EE
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEK---IREQEEKRQEEEKI 372
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ ++ E + E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E+ ++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E ++R+ E+++R ++ ++ + +K EE++ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VTKLEKSIDDLEEKV 260
+ + E + EEK+
Sbjct: 553 MREQEVRLRQQEEKM 567
Score = 77.8 bits (190), Expect = 1e-14
Identities = 56/283 (19%), Positives = 133/283 (46%), Gaps = 10/283 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEEDIAAKEKLLRVSEDERDR 59
+ ++ K+Q ++++ +R Q + +K E++ ++ EE I +E+ +R E++ R
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + E+ + EE + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADES------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 173
++ E ++ E + ++ EE M+ QE ++ E + + + + +E K+ E
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+ E++ E ++R+ EE ++ ++ + + K EE+++ +K++
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 234 EAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E E + E + + E+ + + EEK+ +E+ + + +
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 75.1 bits (183), Expect = 7e-14
Identities = 54/252 (21%), Positives = 119/252 (47%), Gaps = 21/252 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ ++++ +M+ +E + E+ +K E K+ EE+ +++ + E + R
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E++ + E+ + EE + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K + R EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK--------------MRRQEE 495
Query: 182 RAELSEGQVRQLEEQLR----IMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKE 234
+ E ++R+ EE++R +M + + + E+K ++E++ EE+++ +K++E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 235 AETRAEFAERSV 246
E R E +
Sbjct: 556 QEVRLRQQEEKM 567
Score = 73.6 bits (179), Expect = 2e-13
Identities = 54/253 (21%), Positives = 122/253 (48%), Gaps = 8/253 (3%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED------ERDRVLEELHKAEDSLLA 73
++ ++ E + E++ ++ EE + KE+ +R E+ E+ R LEE ++ +
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 74 AEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
EE + E R+ Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EG++ +
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 194 EEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
E +++ ++ ++ + +K EE+I+ + ++E E + E + + E+ +
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 254 DDLEEKVAHAKEE 266
+ EEK+ +E+
Sbjct: 540 QEQEEKMRRQEEK 552
Score = 65.5 bits (158), Expect = 5e-11
Identities = 72/306 (23%), Positives = 132/306 (43%), Gaps = 50/306 (16%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K ++QM ++A+ + E D + S + ++ + + + DR +EEL
Sbjct: 127 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 186
Query: 65 HKAEDSL--------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
K D+L + EE K A L ++QLVE E Q + +KLE A
Sbjct: 187 TKERDALSLELYRNTITDEELKEKN----AKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 117 ---------EKAADESERGMKVIESRAQ--------------KDEEKMEIQEIQLKEAKH 153
+ AD + ++ + ++ Q + EEKM QE +++E +
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 154 IAEDADRKYEEVARKLVIIES-------DLERAEERAELSEGQVRQLEEQL----RIMDQ 202
++ + K E K+ E + R EE E ++R+LEE++ +I +Q
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
K E+K ++E R E+E K+ +K++E E + E + + E+ + + EEK+
Sbjct: 363 EEK--RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 261 AHAKEE 266
+EE
Sbjct: 421 WEQEEE 426
Score = 62.8 bits (151), Expect = 3e-10
Identities = 40/194 (20%), Positives = 93/194 (47%), Gaps = 2/194 (1%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K++ Q K+ ++ ++ + E + E+ ++ EE + +E+ + E+E E++
Sbjct: 377 KRQEQEAKMWRQE--EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ E+ + E+ + E + +Q EE++ + ++ K++E E+ E
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
++ E + ++ EEK+ QE ++E + + + K E K+ E + R EE+
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 185 LSEGQVRQLEEQLR 198
E ++RQ EE+++
Sbjct: 555 EQEVRLRQQEEKMQ 568
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 82.0 bits (201), Expect = 5e-16
Identities = 60/269 (22%), Positives = 130/269 (48%), Gaps = 31/269 (11%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAE 82
+Q E E++ ++ EE + +E +R E++ R E++H+ E+ + E+ + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGQVRQLEE----QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV---------LSDK 231
E ++++ EE Q +++ Q K E + Q+E +E+E K+ +K
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++E E R E + + E + +LEE++
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 79.0 bits (193), Expect = 5e-15
Identities = 55/245 (22%), Positives = 126/245 (51%), Gaps = 15/245 (6%)
Query: 24 QAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEA 83
+ E + E++ + EE + +E+ +R ED+ R E++ + E+ + EE + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQT 203
QE +++E + + +D + K EV K+ E ++ EE+ + E ++++ EE+ ++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVA 261
LK Q+E +E+E K+ +K+ E E + + E + + E+ + + E ++
Sbjct: 492 LK----------QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 262 HAKEE 266
+E+
Sbjct: 542 QQEEK 546
Score = 74.7 bits (182), Expect = 9e-14
Identities = 66/284 (23%), Positives = 139/284 (48%), Gaps = 27/284 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEEDIAAKEKLLRV 52
+++ K ++Q+ D + L+RA+ Q EAD+ E +S ++AK + +V
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS------VSAKLQA-QV 282
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+E +L + + E+ + EE + E + +I+ EE++ R +E++ +K
Sbjct: 283 EENELWNLLNQ--QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E E E ++ E + ++ EEKM QE +++E E + EE+ R+ I
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKI 397
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E+ +E+ E ++R+ +E++R ++ + E+K + E+ +++ +KL
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQ----EEKL 450
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+E E + + E + + E+ I EEK+ +E+ ++L Q
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 64.7 bits (156), Expect = 9e-11
Identities = 55/231 (23%), Positives = 117/231 (50%), Gaps = 17/231 (7%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
D+ + E + E++ ++ EE + +E+ +R +++ EE+ + E+ + EE
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 80 ----KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ E + + +I+ EEE+ R +E++ + +++ E+ E E M+ E + Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 136 KDEEKMEIQE--IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
+ EEK++ QE IQ +E K ++ K EE K+ E + R EE+ E ++++
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 194 EEQLRIMDQTLK----ALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
EE+++ ++ ++ L E+K ++E R +E L ++L + +AE
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE----LEERLGKLGQKAE 569
Score = 64.3 bits (155), Expect = 1e-10
Identities = 43/205 (20%), Positives = 103/205 (50%), Gaps = 1/205 (0%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + ++ E ++ E+ ++ ++ ++ +E + +EK +R +++ EE+
Sbjct: 371 RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW 430
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E+ + EE E + + ++Q EE++ +E++ +K++E E+ E+
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
+K E + + EEKM QE ++ E + ++ + K + K+ E L + EE+ +
Sbjct: 491 LLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAA 210
E ++++LEE+L + Q + L A
Sbjct: 550 QEVRLQELEERLGKLGQKAELLGGA 574
Score = 63.9 bits (154), Expect = 2e-10
Identities = 59/252 (23%), Positives = 115/252 (45%), Gaps = 31/252 (12%)
Query: 37 KQLEEDIAAKEKLLRVSEDERDRV---LEEL-HKAEDSLLAAEEAAAKAEADVASLNRRI 92
++L+E A ++ LR+ E E+ + +++L K E + L + + EAD
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEAD-------- 265
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
+ +EL +L +++ E + E M E + Q+ EEKM QE++++E +
Sbjct: 266 -RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLKAL 207
+ K E K+ E + R EE+ E ++R+ EE++ +I +Q K
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 208 MAAEDKYSQKED-------------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
E+ + Q+E R E++++ +K++E E E + +LE+ +
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 255 DLEEKVAHAKEE 266
D EEK+ +E+
Sbjct: 445 DQEEKLREVEEK 456
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/234 (21%), Positives = 110/234 (47%), Gaps = 9/234 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ I+++ + + +E ++ E+ + E + ++ +E I +E+ + E++ +
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR------AQERLATALQKLEE 115
E + E+ L EE + E + +IQ EE++ QE+L +K+ E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E M E + Q+ EEKM+ QE +++E + + K +E +L +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Query: 176 LERAEERAELSEGQVRQL-EEQLRIMDQTLKALMAAEDKYS--QKEDRYEEEIK 226
L + ++AEL G R+ ++L + L+ + +++ S Q++D Y ++
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 39.7 bits (91), Expect = 0.003
Identities = 57/285 (20%), Positives = 125/285 (43%), Gaps = 36/285 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+K+ + D+++ L+ +E ++ K++ + + L +D A ++ + + D V
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
K ++ + K V ++L E AQ+R +L LEE
Sbjct: 136 KKRQEKMNEKNYTFRKR---VVIKKPWLRLGEVT---AQKRPENSL--LEETLHFDHAVR 187
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES---------- 174
G + + ++D +E+ + + E+ K E+ KL ++ES
Sbjct: 188 MGTYIEKLTKERDAPSLELYRNTITD-----EELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 175 DLERAEERAEL------SEGQVRQLEEQLRIMDQTLKALMAAEDKYS----QKED---RY 221
DL+R ERA+L + + +L ++L+ + L+A + + ++ Q+E+ R
Sbjct: 243 DLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ +K+ E E + E + + E+ + + EEK+ +++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 82.0 bits (201), Expect = 5e-16
Identities = 60/269 (22%), Positives = 130/269 (48%), Gaps = 31/269 (11%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAE 82
+Q E E++ ++ EE + +E +R E++ R E++H+ E+ + E+ + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGQVRQLEE----QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV---------LSDK 231
E ++++ EE Q +++ Q K E + Q+E +E+E K+ +K
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++E E R E + + E + +LEE++
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 79.0 bits (193), Expect = 5e-15
Identities = 55/245 (22%), Positives = 126/245 (51%), Gaps = 15/245 (6%)
Query: 24 QAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEA 83
+ E + E++ + EE + +E+ +R ED+ R E++ + E+ + EE + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQT 203
QE +++E + + +D + K EV K+ E ++ EE+ + E ++++ EE+ ++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVA 261
LK Q+E +E+E K+ +K+ E E + + E + + E+ + + E ++
Sbjct: 492 LK----------QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 262 HAKEE 266
+E+
Sbjct: 542 QQEEK 546
Score = 74.7 bits (182), Expect = 9e-14
Identities = 66/284 (23%), Positives = 139/284 (48%), Gaps = 27/284 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEEDIAAKEKLLRV 52
+++ K ++Q+ D + L+RA+ Q EAD+ E +S ++AK + +V
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS------VSAKLQA-QV 282
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+E +L + + E+ + EE + E + +I+ EE++ R +E++ +K
Sbjct: 283 EENELWNLLNQ--QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E E E ++ E + ++ EEKM QE +++E E + EE+ R+ I
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKI 397
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E+ +E+ E ++R+ +E++R ++ + E+K + E+ +++ +KL
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQ----EEKL 450
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+E E + + E + + E+ I EEK+ +E+ ++L Q
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 64.7 bits (156), Expect = 9e-11
Identities = 55/231 (23%), Positives = 117/231 (50%), Gaps = 17/231 (7%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
D+ + E + E++ ++ EE + +E+ +R +++ EE+ + E+ + EE
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 80 ----KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ E + + +I+ EEE+ R +E++ + +++ E+ E E M+ E + Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 136 KDEEKMEIQE--IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
+ EEK++ QE IQ +E K ++ K EE K+ E + R EE+ E ++++
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 194 EEQLRIMDQTLK----ALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
EE+++ ++ ++ L E+K ++E R +E L ++L + +AE
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE----LEERLGKLGQKAE 569
Score = 64.3 bits (155), Expect = 1e-10
Identities = 43/205 (20%), Positives = 103/205 (50%), Gaps = 1/205 (0%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + ++ E ++ E+ ++ ++ ++ +E + +EK +R +++ EE+
Sbjct: 371 RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW 430
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E+ + EE E + + ++Q EE++ +E++ +K++E E+ E+
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
+K E + + EEKM QE ++ E + ++ + K + K+ E L + EE+ +
Sbjct: 491 LLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAA 210
E ++++LEE+L + Q + L A
Sbjct: 550 QEVRLQELEERLGKLGQKAELLGGA 574
Score = 63.9 bits (154), Expect = 2e-10
Identities = 59/252 (23%), Positives = 115/252 (45%), Gaps = 31/252 (12%)
Query: 37 KQLEEDIAAKEKLLRVSEDERDRV---LEEL-HKAEDSLLAAEEAAAKAEADVASLNRRI 92
++L+E A ++ LR+ E E+ + +++L K E + L + + EAD
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEAD-------- 265
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
+ +EL +L +++ E + E M E + Q+ EEKM QE++++E +
Sbjct: 266 -RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLKAL 207
+ K E K+ E + R EE+ E ++R+ EE++ +I +Q K
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 208 MAAEDKYSQKED-------------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
E+ + Q+E R E++++ +K++E E E + +LE+ +
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 255 DLEEKVAHAKEE 266
D EEK+ +E+
Sbjct: 445 DQEEKLREVEEK 456
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/234 (21%), Positives = 110/234 (47%), Gaps = 9/234 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ I+++ + + +E ++ E+ + E + ++ +E I +E+ + E++ +
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR------AQERLATALQKLEE 115
E + E+ L EE + E + +IQ EE++ QE+L +K+ E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E M E + Q+ EEKM+ QE +++E + + K +E +L +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Query: 176 LERAEERAELSEGQVRQL-EEQLRIMDQTLKALMAAEDKYS--QKEDRYEEEIK 226
L + ++AEL G R+ ++L + L+ + +++ S Q++D Y ++
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 38.9 bits (89), Expect = 0.005
Identities = 57/285 (20%), Positives = 125/285 (43%), Gaps = 36/285 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+K+ + D+++ L+ +E ++ K++ + + L +D A ++ + + D V
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
K ++ + K V ++L E AQ+R +L LEE
Sbjct: 136 KKRQEKMNEKNYTFRKR---VVIKKPWLRLGEVT---AQKRPENSL--LEETLHFDHAVR 187
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES---------- 174
G + + ++D +E+ + + E+ K E+ KL ++ES
Sbjct: 188 MGTYIEKLTKERDALSLELYRNTITD-----EELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 175 DLERAEERAEL------SEGQVRQLEEQLRIMDQTLKALMAAEDKYS----QKED---RY 221
DL+R ERA+L + + +L ++L+ + L+A + + ++ Q+E+ R
Sbjct: 243 DLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ +K+ E E + E + + E+ + + EEK+ +++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 82.0 bits (201), Expect = 5e-16
Identities = 51/255 (20%), Positives = 126/255 (49%), Gaps = 3/255 (1%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED---ERDRVLEELHKAEDS 70
+K ++ ++ EA E++ ++ EE I +E+ + E+ E++++ EE + E
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 71 LLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
+ +E + + ++ +I EE++ + +E++ +K+ + E+ E E +
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
E + ++ EEK+ QE +++E + + ++ + K E K+ E ++ EE+ E ++
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
R+ E+++R ++ ++ + +K EE++ +K++E E + E + + E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 251 KSIDDLEEKVAHAKE 265
+ EEK+ +E
Sbjct: 704 VRLRQQEEKMQEHQE 718
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/279 (23%), Positives = 143/279 (51%), Gaps = 19/279 (6%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED---ERDRVLE 62
++ + + +KE + R E+ +K E++ ++ EE + KE+ +R E+ E++++ E
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 63 ELHKA-EDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ K E+ + +E + EA + +I+ EE++ +E++ +K+ E EK +
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 122 ESERGMKVIESRAQKDEEKMEIQEI-QLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E +R + E +++E+ E +EI + KE H E+ RK EE K+ E + E
Sbjct: 516 EEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE---KMWRQEEKMHDQE 570
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAET 237
E+ E +V + EE++R ++ ++ E+K ++E+ EE++ +K+ E E
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIRE---QEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ + E + + E+ I + E+K+ +E+ +M+ +
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Score = 77.0 bits (188), Expect = 2e-14
Identities = 55/244 (22%), Positives = 125/244 (51%), Gaps = 7/244 (2%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ I+++ + ++ +E + E+ +K E+ +Q +E++ +E+ +R ++E R
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 542
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E++H+ E+ + EE + E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E + E + + EEKM QE +++E + + K E +K I E+ E
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK---IREQEEKIRE 659
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR-YEEEIKV--LSDKLKEAETR 238
+ E+ + Q ++ EQ M + + + E+K ++E++ +E+E+++ +K++E +
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719
Query: 239 AEFA 242
E A
Sbjct: 720 LEAA 723
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/259 (22%), Positives = 129/259 (49%), Gaps = 17/259 (6%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ ++ E + E++ ++ EE + +E+++ E++ R E + + E+ + EE
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE------SERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 435 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEV---ARKLVIIESDLERAEERAELSEGQV 190
++ EEKM QE ++ E + I E+ R+ +E + + + ++ R +E+ E ++
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRAEFAERSVT 247
R+ EE++ ++ + E+K ++E+ R EE+I+ +K++E E + E
Sbjct: 553 RKQEEKMWRQEEKMH---DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 248 KLEKSIDDLEEKVAHAKEE 266
+ E+ + + EEK+ +E+
Sbjct: 610 EQEEKMGEQEEKMCEQEEK 628
Score = 74.7 bits (182), Expect = 9e-14
Identities = 62/279 (22%), Positives = 131/279 (46%), Gaps = 25/279 (8%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + + +KE + R E+ +K E++ ++LEE + +EK + E E R EE
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEK---IREQEEKRQEEEKI 466
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ ++ E + E + +I+ EE++ R +E++ +K+ E EK ++ E
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEM 525
Query: 126 GMKVIESRAQKD-----------EEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + R Q++ EEK+ QE ++ + D + K E K+ E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTL----KALMAAEDKYSQKED---RYEEEIKV 227
+ EE+ E ++R+ EE + ++ + + + E+K ++E+ R EE+I+
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
K++E E + E + + E+ + + EEK+ +E+
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Score = 66.2 bits (160), Expect = 3e-11
Identities = 60/264 (22%), Positives = 124/264 (46%), Gaps = 32/264 (12%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQ--------LEEDIAAKEKLLRVSEDERDRVLEELH 65
++E ++ E+ + ++K E +Q EE I +E+ +R E++ R E++H
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E + EE + E +EE R QE + +K+ E E+ + E
Sbjct: 509 EQEK--IREEEKRQEQEE---------MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M + EEKM QE +++E + E R+ E++ + I E+ E+ E+
Sbjct: 558 KM-------WRQEEKMHDQEEKIREQE---EKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETRAEFA 242
++ Q ++ EQ M + + + E+K ++E++ E++I+ +K++E E +
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 243 ERSVTKLEKSIDDLEEKVAHAKEE 266
E + + E+ + + EEK+ +E+
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 58.2 bits (139), Expect = 8e-09
Identities = 62/301 (20%), Positives = 130/301 (43%), Gaps = 46/301 (15%)
Query: 12 KLDKENAL--DRAEQAEADKKAAEDRSKQLEEDIAAKEKLL--RVSEDERDRVLEELHKA 67
+L ++NA ++ + E++K + K+L+ + + LL + + E D + +EL
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 68 EDSLLAAEEAAA-------KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
L A E + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E M E + ++ EE M +E +++ + + + + K E+ K+ E E+ E
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 181 ERAE------------------LSEGQVRQLEEQLRIMDQTL---------KALMAAEDK 213
+R E E ++R+ EE++R ++ + + + E+K
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK 518
Query: 214 YSQKED--------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
++E+ R +EEI +K+ E E + E + + E+ + D EEK+ +E
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578
Query: 266 E 266
+
Sbjct: 579 K 579
Score = 57.0 bits (136), Expect = 2e-08
Identities = 59/282 (20%), Positives = 122/282 (43%), Gaps = 35/282 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K ++QM ++A+ + E D + S + ++ + + + DR +EEL
Sbjct: 200 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 259
Query: 65 HKAEDSL--------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
K D+L + EE K A L ++QLVE E Q + +KLE A
Sbjct: 260 TKERDALSLELYRNTITDEELKEKN----AKLQEKLQLVESEKSEIQLNVKELKRKLERA 315
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIES 174
+ + + +A+ D E+Q + K + E+ +R ++ K+ E
Sbjct: 316 KLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 368
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
++ EE+ + E ++R+ EE++R ++ ++ Q+E +E+E +K++
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRR---------QEEMMWEKE-----EKMRR 414
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E E + + E+ + + EEK+ +E+ ++ +Q
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 81.3 bits (199), Expect = 9e-16
Identities = 58/273 (21%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
++ + S AQK+E +++E Q +L+ H E A + + + +E+ +
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK--SKFKSTIAALEAKIA 1824
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ EE+ E + + + L+ D+ LK ++ + + ++Y+E+ + + ++K+ +
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
+ E AE ++ + L+ ++ A E N +M
Sbjct: 1885 QLEEAEEESQRINANRRKLQRELDEATESNEAM 1917
Score = 65.9 bits (159), Expect = 4e-11
Identities = 74/292 (25%), Positives = 139/292 (47%), Gaps = 41/292 (14%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 987
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 988 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 132 SRAQKDEE-KMEIQEIQLK---EAKHIAE---DADRKYEEVARKLVIIESDLERAEERAE 184
R +K+E+ + E+++++ K +A E D + E+ +L E +L+ A R +
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 185 LSEGQ-------VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA-- 235
Q +R+LE + + + L + AA +K +++ EE++ L +L++
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 236 ------ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1161 STATQQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1208
Score = 65.5 bits (158), Expect = 5e-11
Identities = 50/246 (20%), Positives = 113/246 (45%), Gaps = 7/246 (2%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ +E+ ++ EDE + E KAE+ L E+ ++ + L ++Q E A
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 906
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
+E K +E E+ E E ++ E R Q+ + + + Q+ + + E+ +
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA--AEDKYSQK--- 217
+++ + V E+ +++ E+ + + Q +L ++ +++++ + L AE++ K
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 218 --EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++++E I L +LK+ E + E+ KLE D E++A + + + L
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 276 QTLLEL 281
+ EL
Sbjct: 1087 KKEEEL 1092
Score = 64.7 bits (156), Expect = 9e-11
Identities = 54/269 (20%), Positives = 119/269 (44%), Gaps = 7/269 (2%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 957
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L E ++ L
Sbjct: 958 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1012
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
L ++ K L ++K+ E +K +E E E + + I
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
Query: 255 DLEEKVAHAKEENLSMHQMLDQTLLELNN 283
DL+ ++A K + + L L L++
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDD 1101
Score = 64.3 bits (155), Expect = 1e-10
Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 48/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR--------IMDQTLKALMAAE- 211
+ EE+A +L S ++ E ++ QLEE+L + D+ KA AE
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 212 ------------DKYSQKEDRYEEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLE 257
K + E + K L KL E E +++F + ++ LE I LE
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KSTIAALEAKIAQLE 1827
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+V E + + L Q
Sbjct: 1828 EQVEQEAREKQAATKSLKQ 1846
Score = 61.6 bits (148), Expect = 7e-10
Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1349 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ +++Q + L + + L++ +K +K D+ E K +S
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/299 (23%), Positives = 130/299 (43%), Gaps = 45/299 (15%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR-----------RIQLVEEEL 99
R +E + + EL DS +E AK E +V L + ++Q + ++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 100 DRAQERLATALQKLEEAEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQL 148
+A E L L++ + A+ D++++ + +V+ Q+ E K + E Q+
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ-------VRQLEEQLRIMD 201
+E + D +R E+ K+ +++++E +EG+ V L QL+
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 202 QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ L+ + S K + EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Score = 57.4 bits (137), Expect = 1e-08
Identities = 69/315 (21%), Positives = 146/315 (46%), Gaps = 45/315 (14%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL-------EEDIAAKEKLLRVSEDER 57
+++MQ + + + +R ++AE + K E + QL +E + A+ +L +E+ R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 58 DRV------LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR---AQERL- 106
R+ LEE LH+ E L E+ + +A+ + +++ +EE+L+ A+++L
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 107 ------ATALQKLEEAEKAADESERGM----KVIESR--------AQKDEEKMEIQEIQL 148
++KLE+ D+ + K++E R A+++E+ + +++
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 149 KEAKHIAE-DADRKYEEVARKLV-----IIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
K I+E + K EE +R+ + +E D E+ + Q+ +L+ QL ++
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
L+A +A D +++ ++I+ L + + + + + K EK DL E++
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 263 AKEENLSMHQMLDQT 277
K E + LD T
Sbjct: 1151 LKTE---LEDTLDST 1162
Score = 57.4 bits (137), Expect = 1e-08
Identities = 64/304 (21%), Positives = 134/304 (44%), Gaps = 46/304 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEE------------------- 98
E + E SL A E A +A+ ++ N+ ++ E+
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 99 --LDRAQERLATALQKLEEAEKAADESERGMKV------------IESRAQKDEEKMEIQ 144
L+ E + T L++LE+ +A ++++ ++V +++R +++EEK
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA-------ELSEGQVRQLEEQL 197
+ QL E + ED ++ A +E DL+ E +A E + Q+R+L+ Q+
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
+ + L+ A+ D+ E++ K L L + + AER+ + + ++L
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 258 EKVA 261
E++A
Sbjct: 1715 EELA 1718
Score = 50.8 bits (120), Expect = 1e-06
Identities = 71/352 (20%), Positives = 142/352 (40%), Gaps = 68/352 (19%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIA---------AKE 47
+ A +KKM LD E L+ E A + +K AE + K+LE++I +KE
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 48 KLL---RVS--------EDERDRVLEELHKAEDSLLAAEEAAAKAE-------------- 82
+ L R+S E+E+ + L +L +S+++ E K E
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1060
Query: 83 ---------------ADVASLNRRIQLVEEELDRAQERLA-------TALQKLEEAEKAA 120
A +A L ++ EEEL A RL AL+K+ E E
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 121 DESERGM---KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
+ + + + ++A+K + + + LK D+ +E+ K + L+
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 178 RA-EERAELSEGQVRQLEEQ----LRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
+A +E E QV+++ ++ + + + L+ A+ + + E+E L+ +L
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1240
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ + E KLE + +L+ K + + ++ + + E+ ++
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/240 (20%), Positives = 106/240 (44%), Gaps = 15/240 (6%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1331 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
+ +K D+ E + I K A++ DR E K S EE E E
Sbjct: 1448 KKQRKFDQLLAEEKNISSK----YADERDRAEAEAREKETKALSLARALEEALEAKE--- 1500
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+LE +++ ++ L++++D + E+ + L +++E +T+ E E + E
Sbjct: 1501 -ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1559
Score = 44.7 bits (104), Expect = 9e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 15/145 (10%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1873
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEE 164
+ + + + E+AD EE
Sbjct: 1934 TSFVPS-RRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 81.3 bits (199), Expect = 9e-16
Identities = 58/273 (21%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
++ + S AQK+E +++E Q +L+ H E A + + + +E+ +
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK--SKFKSTIAALEAKIA 1831
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ EE+ E + + + L+ D+ LK ++ + + ++Y+E+ + + ++K+ +
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
+ E AE ++ + L+ ++ A E N +M
Sbjct: 1892 QLEEAEEESQRINANRRKLQRELDEATESNEAM 1924
Score = 65.9 bits (159), Expect = 4e-11
Identities = 74/292 (25%), Positives = 139/292 (47%), Gaps = 41/292 (14%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 994
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 995 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 132 SRAQKDEE-KMEIQEIQLK---EAKHIAE---DADRKYEEVARKLVIIESDLERAEERAE 184
R +K+E+ + E+++++ K +A E D + E+ +L E +L+ A R +
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 185 LSEGQ-------VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA-- 235
Q +R+LE + + + L + AA +K +++ EE++ L +L++
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 236 ------ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1168 STATQQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1215
Score = 65.5 bits (158), Expect = 5e-11
Identities = 50/246 (20%), Positives = 113/246 (45%), Gaps = 7/246 (2%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ +E+ ++ EDE + E KAE+ L E+ ++ + L ++Q E A
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 913
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
+E K +E E+ E E ++ E R Q+ + + + Q+ + + E+ +
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA--AEDKYSQK--- 217
+++ + V E+ +++ E+ + + Q +L ++ +++++ + L AE++ K
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 218 --EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++++E I L +LK+ E + E+ KLE D E++A + + + L
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 276 QTLLEL 281
+ EL
Sbjct: 1094 KKEEEL 1099
Score = 64.7 bits (156), Expect = 9e-11
Identities = 54/269 (20%), Positives = 119/269 (44%), Gaps = 7/269 (2%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 964
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L E ++ L
Sbjct: 965 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1019
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
L ++ K L ++K+ E +K +E E E + + I
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1079
Query: 255 DLEEKVAHAKEENLSMHQMLDQTLLELNN 283
DL+ ++A K + + L L L++
Sbjct: 1080 DLQAQIAELKMQLAKKEEELQAALARLDD 1108
Score = 64.3 bits (155), Expect = 1e-10
Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 48/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR--------IMDQTLKALMAAE- 211
+ EE+A +L S ++ E ++ QLEE+L + D+ KA AE
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 212 ------------DKYSQKEDRYEEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLE 257
K + E + K L KL E E +++F + ++ LE I LE
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KSTIAALEAKIAQLE 1834
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+V E + + L Q
Sbjct: 1835 EQVEQEAREKQAATKSLKQ 1853
Score = 61.6 bits (148), Expect = 7e-10
Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1356 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ +++Q + L + + L++ +K +K D+ E K +S
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/299 (23%), Positives = 130/299 (43%), Gaps = 45/299 (15%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR-----------RIQLVEEEL 99
R +E + + EL DS +E AK E +V L + ++Q + ++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 100 DRAQERLATALQKLEEAEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQL 148
+A E L L++ + A+ D++++ + +V+ Q+ E K + E Q+
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ-------VRQLEEQLRIMD 201
+E + D +R E+ K+ +++++E +EG+ V L QL+
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 202 QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ L+ + S K + EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Score = 57.4 bits (137), Expect = 1e-08
Identities = 69/315 (21%), Positives = 146/315 (46%), Gaps = 45/315 (14%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL-------EEDIAAKEKLLRVSEDER 57
+++MQ + + + +R ++AE + K E + QL +E + A+ +L +E+ R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 58 DRV------LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR---AQERL- 106
R+ LEE LH+ E L E+ + +A+ + +++ +EE+L+ A+++L
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 107 ------ATALQKLEEAEKAADESERGM----KVIESR--------AQKDEEKMEIQEIQL 148
++KLE+ D+ + K++E R A+++E+ + +++
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 149 KEAKHIAE-DADRKYEEVARKLV-----IIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
K I+E + K EE +R+ + +E D E+ + Q+ +L+ QL ++
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
L+A +A D +++ ++I+ L + + + + + K EK DL E++
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 263 AKEENLSMHQMLDQT 277
K E + LD T
Sbjct: 1158 LKTE---LEDTLDST 1169
Score = 57.4 bits (137), Expect = 1e-08
Identities = 64/304 (21%), Positives = 134/304 (44%), Gaps = 46/304 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEE------------------- 98
E + E SL A E A +A+ ++ N+ ++ E+
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 99 --LDRAQERLATALQKLEEAEKAADESERGMKV------------IESRAQKDEEKMEIQ 144
L+ E + T L++LE+ +A ++++ ++V +++R +++EEK
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA-------ELSEGQVRQLEEQL 197
+ QL E + ED ++ A +E DL+ E +A E + Q+R+L+ Q+
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
+ + L+ A+ D+ E++ K L L + + AER+ + + ++L
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 258 EKVA 261
E++A
Sbjct: 1722 EELA 1725
Score = 50.8 bits (120), Expect = 1e-06
Identities = 71/352 (20%), Positives = 142/352 (40%), Gaps = 68/352 (19%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIA---------AKE 47
+ A +KKM LD E L+ E A + +K AE + K+LE++I +KE
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 48 KLL---RVS--------EDERDRVLEELHKAEDSLLAAEEAAAKAE-------------- 82
+ L R+S E+E+ + L +L +S+++ E K E
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 83 ---------------ADVASLNRRIQLVEEELDRAQERLA-------TALQKLEEAEKAA 120
A +A L ++ EEEL A RL AL+K+ E E
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 121 DESERGM---KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
+ + + + ++A+K + + + LK D+ +E+ K + L+
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 178 RA-EERAELSEGQVRQLEEQ----LRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
+A +E E QV+++ ++ + + + L+ A+ + + E+E L+ +L
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1247
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ + E KLE + +L+ K + + ++ + + E+ ++
Sbjct: 1248 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/240 (20%), Positives = 106/240 (44%), Gaps = 15/240 (6%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
+ +K D+ E + I K A++ DR E K S EE E E
Sbjct: 1455 KKQRKFDQLLAEEKNISSK----YADERDRAEAEAREKETKALSLARALEEALEAKE--- 1507
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+LE +++ ++ L++++D + E+ + L +++E +T+ E E + E
Sbjct: 1508 -ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1566
Score = 44.7 bits (104), Expect = 9e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 15/145 (10%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1880
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEE 164
+ + + + E+AD EE
Sbjct: 1941 TSFVPS-RRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 81.3 bits (199), Expect = 9e-16
Identities = 58/273 (21%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
++ + S AQK+E +++E Q +L+ H E A + + + +E+ +
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK--SKFKSTIAALEAKIA 1831
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ EE+ E + + + L+ D+ LK ++ + + ++Y+E+ + + ++K+ +
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
+ E AE ++ + L+ ++ A E N +M
Sbjct: 1892 QLEEAEEESQRINANRRKLQRELDEATESNEAM 1924
Score = 65.9 bits (159), Expect = 4e-11
Identities = 74/292 (25%), Positives = 139/292 (47%), Gaps = 41/292 (14%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 994
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 995 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 132 SRAQKDEE-KMEIQEIQLK---EAKHIAE---DADRKYEEVARKLVIIESDLERAEERAE 184
R +K+E+ + E+++++ K +A E D + E+ +L E +L+ A R +
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 185 LSEGQ-------VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA-- 235
Q +R+LE + + + L + AA +K +++ EE++ L +L++
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 236 ------ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1168 STATQQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1215
Score = 65.5 bits (158), Expect = 5e-11
Identities = 50/246 (20%), Positives = 113/246 (45%), Gaps = 7/246 (2%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ +E+ ++ EDE + E KAE+ L E+ ++ + L ++Q E A
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 913
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
+E K +E E+ E E ++ E R Q+ + + + Q+ + + E+ +
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA--AEDKYSQK--- 217
+++ + V E+ +++ E+ + + Q +L ++ +++++ + L AE++ K
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 218 --EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++++E I L +LK+ E + E+ KLE D E++A + + + L
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 276 QTLLEL 281
+ EL
Sbjct: 1094 KKEEEL 1099
Score = 64.7 bits (156), Expect = 9e-11
Identities = 54/269 (20%), Positives = 119/269 (44%), Gaps = 7/269 (2%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 964
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L E ++ L
Sbjct: 965 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1019
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
L ++ K L ++K+ E +K +E E E + + I
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1079
Query: 255 DLEEKVAHAKEENLSMHQMLDQTLLELNN 283
DL+ ++A K + + L L L++
Sbjct: 1080 DLQAQIAELKMQLAKKEEELQAALARLDD 1108
Score = 64.3 bits (155), Expect = 1e-10
Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 48/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR--------IMDQTLKALMAAE- 211
+ EE+A +L S ++ E ++ QLEE+L + D+ KA AE
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 212 ------------DKYSQKEDRYEEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLE 257
K + E + K L KL E E +++F + ++ LE I LE
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KSTIAALEAKIAQLE 1834
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+V E + + L Q
Sbjct: 1835 EQVEQEAREKQAATKSLKQ 1853
Score = 61.6 bits (148), Expect = 7e-10
Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1356 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ +++Q + L + + L++ +K +K D+ E K +S
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/299 (23%), Positives = 130/299 (43%), Gaps = 45/299 (15%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR-----------RIQLVEEEL 99
R +E + + EL DS +E AK E +V L + ++Q + ++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 100 DRAQERLATALQKLEEAEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQL 148
+A E L L++ + A+ D++++ + +V+ Q+ E K + E Q+
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ-------VRQLEEQLRIMD 201
+E + D +R E+ K+ +++++E +EG+ V L QL+
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 202 QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ L+ + S K + EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Score = 57.4 bits (137), Expect = 1e-08
Identities = 69/315 (21%), Positives = 146/315 (46%), Gaps = 45/315 (14%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL-------EEDIAAKEKLLRVSEDER 57
+++MQ + + + +R ++AE + K E + QL +E + A+ +L +E+ R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 58 DRV------LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR---AQERL- 106
R+ LEE LH+ E L E+ + +A+ + +++ +EE+L+ A+++L
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 107 ------ATALQKLEEAEKAADESERGM----KVIESR--------AQKDEEKMEIQEIQL 148
++KLE+ D+ + K++E R A+++E+ + +++
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037
Query: 149 KEAKHIAE-DADRKYEEVARKLV-----IIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
K I+E + K EE +R+ + +E D E+ + Q+ +L+ QL ++
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
L+A +A D +++ ++I+ L + + + + + K EK DL E++
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 263 AKEENLSMHQMLDQT 277
K E + LD T
Sbjct: 1158 LKTE---LEDTLDST 1169
Score = 57.4 bits (137), Expect = 1e-08
Identities = 64/304 (21%), Positives = 134/304 (44%), Gaps = 46/304 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEE------------------- 98
E + E SL A E A +A+ ++ N+ ++ E+
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 99 --LDRAQERLATALQKLEEAEKAADESERGMKV------------IESRAQKDEEKMEIQ 144
L+ E + T L++LE+ +A ++++ ++V +++R +++EEK
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA-------ELSEGQVRQLEEQL 197
+ QL E + ED ++ A +E DL+ E +A E + Q+R+L+ Q+
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
+ + L+ A+ D+ E++ K L L + + AER+ + + ++L
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 258 EKVA 261
E++A
Sbjct: 1722 EELA 1725
Score = 50.8 bits (120), Expect = 1e-06
Identities = 71/352 (20%), Positives = 142/352 (40%), Gaps = 68/352 (19%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIA---------AKE 47
+ A +KKM LD E L+ E A + +K AE + K+LE++I +KE
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 48 KLL---RVS--------EDERDRVLEELHKAEDSLLAAEEAAAKAE-------------- 82
+ L R+S E+E+ + L +L +S+++ E K E
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 83 ---------------ADVASLNRRIQLVEEELDRAQERLA-------TALQKLEEAEKAA 120
A +A L ++ EEEL A RL AL+K+ E E
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 121 DESERGM---KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
+ + + + ++A+K + + + LK D+ +E+ K + L+
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 178 RA-EERAELSEGQVRQLEEQ----LRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
+A +E E QV+++ ++ + + + L+ A+ + + E+E L+ +L
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1247
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ + E KLE + +L+ K + + ++ + + E+ ++
Sbjct: 1248 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/240 (20%), Positives = 106/240 (44%), Gaps = 15/240 (6%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
+ +K D+ E + I K A++ DR E K S EE E E
Sbjct: 1455 KKQRKFDQLLAEEKNISSK----YADERDRAEAEAREKETKALSLARALEEALEAKE--- 1507
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+LE +++ ++ L++++D + E+ + L +++E +T+ E E + E
Sbjct: 1508 -ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1566
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 81.3 bits (199), Expect = 9e-16
Identities = 58/273 (21%), Positives = 133/273 (48%), Gaps = 12/273 (4%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
++ + S AQK+E +++E Q +L+ H E A + + + +E+ +
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK--SKFKSTIAALEAKIA 1824
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ EE+ E + + + L+ D+ LK ++ + + ++Y+E+ + + ++K+ +
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
+ E AE ++ + L+ ++ A E N +M
Sbjct: 1885 QLEEAEEESQRINANRRKLQRELDEATESNEAM 1917
Score = 65.9 bits (159), Expect = 4e-11
Identities = 74/292 (25%), Positives = 139/292 (47%), Gaps = 41/292 (14%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 987
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 988 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 132 SRAQKDEE-KMEIQEIQLK---EAKHIAE---DADRKYEEVARKLVIIESDLERAEERAE 184
R +K+E+ + E+++++ K +A E D + E+ +L E +L+ A R +
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 185 LSEGQ-------VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA-- 235
Q +R+LE + + + L + AA +K +++ EE++ L +L++
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 236 ------ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1161 STATQQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1208
Score = 65.5 bits (158), Expect = 5e-11
Identities = 50/246 (20%), Positives = 113/246 (45%), Gaps = 7/246 (2%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ +E+ ++ EDE + E KAE+ L E+ ++ + L ++Q E A
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 906
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
+E K +E E+ E E ++ E R Q+ + + + Q+ + + E+ +
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA--AEDKYSQK--- 217
+++ + V E+ +++ E+ + + Q +L ++ +++++ + L AE++ K
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 218 --EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++++E I L +LK+ E + E+ KLE D E++A + + + L
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 276 QTLLEL 281
+ EL
Sbjct: 1087 KKEEEL 1092
Score = 64.7 bits (156), Expect = 9e-11
Identities = 54/269 (20%), Positives = 119/269 (44%), Gaps = 7/269 (2%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 957
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L E ++ L
Sbjct: 958 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1012
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
L ++ K L ++K+ E +K +E E E + + I
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
Query: 255 DLEEKVAHAKEENLSMHQMLDQTLLELNN 283
DL+ ++A K + + L L L++
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLDD 1101
Score = 64.3 bits (155), Expect = 1e-10
Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 48/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR--------IMDQTLKALMAAE- 211
+ EE+A +L S ++ E ++ QLEE+L + D+ KA AE
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 212 ------------DKYSQKEDRYEEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLE 257
K + E + K L KL E E +++F + ++ LE I LE
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KSTIAALEAKIAQLE 1827
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+V E + + L Q
Sbjct: 1828 EQVEQEAREKQAATKSLKQ 1846
Score = 61.6 bits (148), Expect = 7e-10
Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1349 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ +++Q + L + + L++ +K +K D+ E K +S
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/299 (23%), Positives = 130/299 (43%), Gaps = 45/299 (15%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR-----------RIQLVEEEL 99
R +E + + EL DS +E AK E +V L + ++Q + ++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 100 DRAQERLATALQKLEEAEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQL 148
+A E L L++ + A+ D++++ + +V+ Q+ E K + E Q+
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ-------VRQLEEQLRIMD 201
+E + D +R E+ K+ +++++E +EG+ V L QL+
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 202 QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ L+ + S K + EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Score = 57.4 bits (137), Expect = 1e-08
Identities = 69/315 (21%), Positives = 146/315 (46%), Gaps = 45/315 (14%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL-------EEDIAAKEKLLRVSEDER 57
+++MQ + + + +R ++AE + K E + QL +E + A+ +L +E+ R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 58 DRV------LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDR---AQERL- 106
R+ LEE LH+ E L E+ + +A+ + +++ +EE+L+ A+++L
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 107 ------ATALQKLEEAEKAADESERGM----KVIESR--------AQKDEEKMEIQEIQL 148
++KLE+ D+ + K++E R A+++E+ + +++
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
Query: 149 KEAKHIAE-DADRKYEEVARKLV-----IIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
K I+E + K EE +R+ + +E D E+ + Q+ +L+ QL ++
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 203 TLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
L+A +A D +++ ++I+ L + + + + + K EK DL E++
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 263 AKEENLSMHQMLDQT 277
K E + LD T
Sbjct: 1151 LKTE---LEDTLDST 1162
Score = 57.4 bits (137), Expect = 1e-08
Identities = 64/304 (21%), Positives = 134/304 (44%), Gaps = 46/304 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEE------------------- 98
E + E SL A E A +A+ ++ N+ ++ E+
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 99 --LDRAQERLATALQKLEEAEKAADESERGMKV------------IESRAQKDEEKMEIQ 144
L+ E + T L++LE+ +A ++++ ++V +++R +++EEK
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 145 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA-------ELSEGQVRQLEEQL 197
+ QL E + ED ++ A +E DL+ E +A E + Q+R+L+ Q+
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
+ + L+ A+ D+ E++ K L L + + AER+ + + ++L
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 258 EKVA 261
E++A
Sbjct: 1715 EELA 1718
Score = 50.8 bits (120), Expect = 1e-06
Identities = 71/352 (20%), Positives = 142/352 (40%), Gaps = 68/352 (19%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIA---------AKE 47
+ A +KKM LD E L+ E A + +K AE + K+LE++I +KE
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 48 KLL---RVS--------EDERDRVLEELHKAEDSLLAAEEAAAKAE-------------- 82
+ L R+S E+E+ + L +L +S+++ E K E
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1060
Query: 83 ---------------ADVASLNRRIQLVEEELDRAQERLA-------TALQKLEEAEKAA 120
A +A L ++ EEEL A RL AL+K+ E E
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 121 DESERGM---KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
+ + + + ++A+K + + + LK D+ +E+ K + L+
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 178 RA-EERAELSEGQVRQLEEQ----LRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
+A +E E QV+++ ++ + + + L+ A+ + + E+E L+ +L
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL 1240
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ + E KLE + +L+ K + + ++ + + E+ ++
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/240 (20%), Positives = 106/240 (44%), Gaps = 15/240 (6%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1331 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
+ +K D+ E + I K A++ DR E K S EE E E
Sbjct: 1448 KKQRKFDQLLAEEKNISSK----YADERDRAEAEAREKETKALSLARALEEALEAKE--- 1500
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+LE +++ ++ L++++D + E+ + L +++E +T+ E E + E
Sbjct: 1501 -ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1559
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 79.3 bits (194), Expect = 3e-15
Identities = 59/285 (20%), Positives = 139/285 (48%), Gaps = 23/285 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ I+++ + ++ ++ + E+ +K E+ +Q +E++ +E+ + ++E R
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH-EQEEIWRQK 495
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQ------KLEE 115
E++H+ E+ + EE + E + +I+ EE++ R +E++ + K+ E
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
EK +E +R + E + + EEK+ QE ++ + + + K +E K+ E
Sbjct: 556 QEKIWEEEKRQEQ--EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKA-----------LMAAEDKYSQKED---RY 221
+ EE+ + E ++R+ EE++R ++ + + E+K ++E+ R
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ K++E E + E + + E+ + + EEK+ +E+
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Score = 75.9 bits (185), Expect = 4e-14
Identities = 55/256 (21%), Positives = 126/256 (49%), Gaps = 3/256 (1%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K+KM + ++ + E + E++ ++ EE + +E+ +R ++E R E++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR-EQEEMWREEEKM 553
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
H+ E + EE + E + +I+ EE++ R +E++ +K +E E+ + E
Sbjct: 554 HEQEK--IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
++ E + Q+ EEK+ QE +++E + + ++ + K E K+ E ++ EE
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Query: 185 LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
E ++R+ E+++R ++ ++ + +K EE++ +K++E E + E
Sbjct: 672 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Query: 245 SVTKLEKSIDDLEEKV 260
+ + E + EEK+
Sbjct: 732 KMWEQEVRLRQQEEKM 747
Score = 71.6 bits (174), Expect = 7e-13
Identities = 56/277 (20%), Positives = 136/277 (49%), Gaps = 29/277 (10%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED---ERDRVLE 62
++ + + +KE + R E+ +K E++ ++ EE + KE+ +R E+ E++++ E
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 63 ELHKA-EDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ K E+ + +E + EA + +I+ EE++ ++++ +K+ E EK +
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E +R +++E+M QE ++ E + I ++ +E+ E + + EE
Sbjct: 469 EEKR----------QEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--------EEKIRKQEE 510
Query: 182 RAELSEGQVRQLEEQLRIMDQTL----KALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+ E ++R+ EE++R ++ + + + E+ + ++E +E+E +K +E E
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ E + + E+ + EEK+ +E+ + +
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Score = 67.4 bits (163), Expect = 1e-11
Identities = 65/284 (22%), Positives = 133/284 (46%), Gaps = 33/284 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLL----RVSEDERDRVL 61
++ + + +KE + R E+ +K E++ ++LEE + +EK+ + E+E+ R
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRI-----------QLVEEELDRAQERLATAL 110
E+ + E + EE + E + +++ ++ EEE + QE +
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY---EEVAR 167
+K+ E E+ + E+ M E + +K EEK+ QE +++E + + + K EE R
Sbjct: 483 EKIHEQEEIWRQKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 168 KLVIIESDLERAEERAELSEGQVRQLEE------QLRIMDQTLKALMAAEDKYSQKEDRY 221
+ + + E+ E+ ++ E + RQ +E + +I +Q K E Q+E R
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
E+E +K+ + E + E + + E+ I + EEK+ +E
Sbjct: 602 EQE-----EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 66.6 bits (161), Expect = 2e-11
Identities = 61/260 (23%), Positives = 127/260 (48%), Gaps = 25/260 (9%)
Query: 12 KLDKENAL--DRAEQAEADKKAAEDRSKQLEEDIAAKEKLL--RVSEDERDRVLEELHKA 67
+L ++NA ++ + E++K + K+L+ + + LL + + E D + +EL
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL--- 274
Query: 68 EDSLLAAEEAAAKAEADVAS---LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ +AK +A V NR Q EE++ R +E++ +K++E E+ E E
Sbjct: 275 -------QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
++ E + ++ EE M +E +++ + + + + K + E + R EE
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 185 LSEGQVRQLEEQL----RIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETR 238
E ++R+LEE++ +I +Q K E+K ++E R E+E K+ +K++E E +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 239 AEFAERSVTKLEKSIDDLEE 258
E+ + + E+ I + E+
Sbjct: 446 IREQEKKMWRQEEKIHEQEK 465
Score = 65.9 bits (159), Expect = 4e-11
Identities = 43/204 (21%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ ++ E E++ ++ EE + +E+ +R E++R E++ K E+ + EE
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
+ E + +I+ EE +E++ +K+ E E+ E E M E + ++ E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRI 199
K+ QE +++E + + ++ + K E K+ E ++ EE+ E ++ + E +LR
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR- 741
Query: 200 MDQTLKALMAAEDKYSQKEDRYEE 223
Q+E++ +E
Sbjct: 742 ----------------QQEEKMQE 749
Score = 65.1 bits (157), Expect = 7e-11
Identities = 62/246 (25%), Positives = 125/246 (50%), Gaps = 26/246 (10%)
Query: 37 KQLEEDIAAKEKLLRVSEDERDRV---LEEL-HKAEDSLLAAEEAAAKAEAD-----VAS 87
++L+E A ++ L++ E E+ + ++EL K E + L + +AEAD + S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIM 200
M QE + E E+ R+ EE+ + E + R EE E ++R+ EE +
Sbjct: 337 MRRQEEMMWEK----EEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 201 DQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++ ++ L E + Q++ R +EE + +K++E E R E E + + E+ I + EEK+
Sbjct: 390 EEKIREL--EEKMHEQEKIREQEEKRQEEEKIREQEKRQE-QEAKMWRQEEKIREQEEKI 446
Query: 261 AHAKEE 266
+++
Sbjct: 447 REQEKK 452
Score = 62.8 bits (151), Expect = 3e-10
Identities = 58/277 (20%), Positives = 134/277 (48%), Gaps = 29/277 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEEDIAAKEKLLRVSEDERDR 59
+ ++ K+Q ++++ +R Q + +K E++ ++ EE I +E+ +R E++
Sbjct: 274 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E++ + E+ + EE + E + EE++ R +E + +K+ E+
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQE-------EMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
E E ++ +E +K E+ +I+E +E K E+ R+ E+ + E+ + R
Sbjct: 386 MWEKEEKIRELE---EKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQ----EAKMWRQ 435
Query: 180 EERAELSEGQVRQLEEQLRIMDQTL--KALMAAEDKYSQKEDRYEEEIKV--------LS 229
EE+ E ++R+ E+++ ++ + + + E+K ++E+ + +E K+
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+K+ E E + E V + E+ I + EEK+ +E+
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 62.4 bits (150), Expect = 4e-10
Identities = 62/279 (22%), Positives = 126/279 (45%), Gaps = 29/279 (10%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K ++QM ++A+ + E D + S + ++ + + + DR +EEL
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 198
Query: 65 HKAEDSL--------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
K D+L + EE K A L ++QLVE E Q + +KLE A
Sbjct: 199 TKERDALSLELYRNTITDEELKEKN----AKLQEKLQLVESEKSEIQLNVKELKRKLERA 254
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIES 174
+ + + +A+ D E+Q + K + E+ +R ++ K+ E
Sbjct: 255 KLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLK----ALMAAEDKYSQKED---RYEEEIKV 227
++ EE+ + E ++R+ EE++R ++ ++ + E+K ++E+ EE+++
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ + E E + E + + E+ I +LEEK+ H +E+
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM-HEQEK 405
Score = 57.8 bits (138), Expect = 1e-08
Identities = 56/273 (20%), Positives = 131/273 (47%), Gaps = 15/273 (5%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
++K+Q + + ++ + E + E++ ++ EE + KE+ +R E+ E++
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ E+ + EE + E + +I+ +EE++ QE++ +K +E EK ++ +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEK 424
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
R + E++ + EEK+ QE +++E + + R+ E++ + I E + + +E
Sbjct: 425 RQEQ--EAKMWRQEEKIREQEEKIREQE---KKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 185 LSEGQVRQLEE---QLRIMDQTLKALMAAEDKYSQKEDRY---EEEIKVLSDKLKEAETR 238
E ++ + EE Q M + + + E+K ++E++ EE+I+ +K+ E +
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 239 AEFAE---RSVTKLEKSIDDLEEKVAHAKEENL 268
E R K+ + EE+ +E+ +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 79.3 bits (194), Expect = 3e-15
Identities = 59/266 (22%), Positives = 121/266 (45%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ +++++E K+ E QL+E++A+ E+ R +E ERD +
Sbjct: 1654 MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+E+ + A + + EA +A L EEEL+ Q + + +
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQL-------EEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE--------VARKLVII 172
D + S AQK + + E Q KE K ++ + + + K+ +
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E LE+ + + VR+ E++L+ + ++ D+Y ++ ++ +K L +L
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE A A S KL++ +DD E
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATE 1912
Score = 66.2 bits (160), Expect = 3e-11
Identities = 56/239 (23%), Positives = 118/239 (49%), Gaps = 26/239 (10%)
Query: 49 LLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT 108
LL+V+ E EEL ++ LL +E K E ++ + R+ Q + EE + E+L
Sbjct: 844 LLQVTRQE-----EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA 898
Query: 109 ALQKLEEAEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 161
+ EAE+ E E + +ESR +++EE+ +I + + K+ + +D + +
Sbjct: 899 ETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 162 YEE---VARKL----VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTL---KALMAAE 211
+E +KL V E+ +++ EE L E Q + ++ ++M+ + + +A E
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 212 DKYSQK----EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
++ ++ ++ E I L ++LK+ E + E++ KL+ DL++++A + +
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Score = 65.5 bits (158), Expect = 5e-11
Identities = 62/305 (20%), Positives = 143/305 (46%), Gaps = 25/305 (8%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + K+ ++ +A ++ + +ERDR
Sbjct: 1418 LEKTKNRLQQELDDLTVDLDHQRQVASN---LEKKQKKFDQLLAEEKSISARYAEERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ + N++++ E+L +++ + + +LE+++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
Query: 118 KAADESERGMKV----IESRAQKDEEKMEIQEIQLKEAK----HIAEDADRKYEEVARKL 169
+A ++ M+ +E Q E+ E+ ++ K + D + EE R L
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 170 V----IIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEI 225
+ +E++LE ++ L+ +++E L+ ++ ++A A D+ ++ + + ++
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 226 KVLSDKLKEAE-------TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
K +L+EA +++ +E+ + LE I L+E++A ++ Q D+
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 279 LELNN 283
E+ N
Sbjct: 1715 DEITN 1719
Score = 65.1 bits (157), Expect = 7e-11
Identities = 72/305 (23%), Positives = 141/305 (46%), Gaps = 39/305 (12%)
Query: 4 IKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLE 62
++ MQ +K E L R EQ E K+ + ++LE ++ + K ++ + ++
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 63 ELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+L E + EAA KA +V R++Q ++ Q L A +E + E
Sbjct: 1625 DLKDLEAQI----EAANKARDEVIKQLRKLQA---QMKDYQRELEEARASRDEIFAQSKE 1677
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
SE+ +K +E+ E +++QE +L ++ A+++ +E+A ++ S +
Sbjct: 1678 SEKKLKSLEA------EILQLQE-ELASSERARRHAEQERDELADEITNSASGKSALLDE 1730
Query: 183 AELSEGQVRQLEEQLR-----------------IMDQTLKALMAAEDKYSQKED----RY 221
E ++ QLEE+L + TL A +AAE +QK D +
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQL 1790
Query: 222 EEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
E + K L KL+E E +++F + +++ LE I LEE++ +E + ++++ +T
Sbjct: 1791 ERQNKELKAKLQELEGAVKSKF-KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 280 ELNNM 284
+L +
Sbjct: 1850 KLKEI 1854
Score = 62.4 bits (150), Expect = 4e-10
Identities = 68/280 (24%), Positives = 128/280 (45%), Gaps = 45/280 (16%)
Query: 5 KKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
KKKMQ D E LD E A + +K AE + K++EE+I + ED+ +
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEIL-------LLEDQNSKF 997
Query: 61 LEELHKAED------SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
++E ED S LA EE AK ++A + + +++ +L+ ++ Q+LE
Sbjct: 998 IKEKKLMEDRIAECSSQLAEEEEKAK---NLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 115 EAEKAADESERGMK--VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+A++ D ++ + E +AQ DE K+++ +K EE+ L
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLA---------------KKEEELQGALA-- 1097
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
D E + L VR+L+ Q+ + + ++ A+ +K +++ EE++ L +L
Sbjct: 1098 RGDDETLHKNNALKV--VRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQ 272
++ + TK E+ + +L++ A EE H+
Sbjct: 1156 EDTLDTTAAQQELRTKREQEVAELKK----ALEEETKNHE 1191
Score = 58.5 bits (140), Expect = 6e-09
Identities = 57/253 (22%), Positives = 109/253 (43%), Gaps = 15/253 (5%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL----AAEEAA 78
E +A + AE + + L E++ A + L + D E K E + A EE
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 79 AKAEADVASLNRR----IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
EA + + +R ++ + E+L++A+ A + + E E +KV++
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD-------LERAEERAELSE 187
+ E K + + Q++E + DR E+A K ++++ LE AE++
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 188 GQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
LE QL+ + L+ + S + + EEE L ++ +E E + E+ V
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 248 KLEKSIDDLEEKV 260
L+ + D ++KV
Sbjct: 1368 ALQSQLADTKKKV 1380
Score = 58.2 bits (139), Expect = 8e-09
Identities = 68/289 (23%), Positives = 132/289 (45%), Gaps = 46/289 (15%)
Query: 12 KLDKENALDRAEQAEADKKAA--EDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED 69
++++E ++ Q E K A +D +QL+E+ A++KL + E+ ++ K E+
Sbjct: 930 RVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL----QLEKVTAEAKIKKMEE 985
Query: 70 SLLAAEEAAAKAEADVASLNRRI-----QLVEEE--------LDRAQERLATAL-QKLEE 115
+L E+ +K + + RI QL EEE + QE + + L ++L++
Sbjct: 986 EILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKK 1045
Query: 116 AEKAADESERGMK------------VIESRAQKDEEKMEI--QEIQLKEAKHIAED---- 157
EK E E+ + + E +AQ DE K+++ +E +L+ A +D
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLH 1105
Query: 158 ---ADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRI----MDQTLKALMAA 210
A + E+ ++ ++ D E + +E Q R L E+L ++ TL A
Sbjct: 1106 KNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQ 1165
Query: 211 EDKYSQKEDRYEEEIKVLSDKLKEAETR-AEFAERSVTKLEKSIDDLEE 258
++ +++E E K L ++ K E + + +R T LE+ + LE+
Sbjct: 1166 QELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
Score = 56.6 bits (135), Expect = 2e-08
Identities = 54/288 (18%), Positives = 127/288 (44%), Gaps = 24/288 (8%)
Query: 4 IKKKMQMLKLDKENALD----------RAEQAEAD-KKAAEDRSKQLEEDIAAKEKLLRV 52
+ ++++ LK + E+ LD + EQ A+ KKA E+ +K E I +
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+ +E LE+ + + +L ++ ++A + +Q V+ E + +++L +Q+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
L D R + E+ ++Q +L + E+A++K + A+ +
Sbjct: 1264 LHAKVSEGDRL---------RVELAEKASKLQN-ELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
ES L+ +E + Q L ++R +++ +L +++ + E+++ L +L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 233 KEAETRAEFAERSVTKLEKSIDDL---EEKVAHAKEENLSMHQMLDQT 277
+ + + + ++ LE++ L E ++ EE + L++T
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKT 1421
Score = 54.7 bits (130), Expect = 9e-08
Identities = 60/303 (19%), Positives = 136/303 (44%), Gaps = 37/303 (12%)
Query: 12 KLDKENALDRAEQAEADKKAAE--DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED 69
KLD + A+ +E D+ E +++ +L+ ++ LL +E + + ++ E
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Query: 70 SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
L +E + +L+ RI+ +EEE + QE + EE E+A E+ +
Sbjct: 1316 QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE-------QQEEEEEARKNLEKQVLA 1368
Query: 130 IESRAQKDEEKM-----------EIQEIQLKEAKHIAEDADRK---YEEVARKLVIIESD 175
++S+ ++K+ E ++ LK+A+ +++ + K Y+++ + ++ +
Sbjct: 1369 LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIK-------VL 228
L+ + LE++ + DQ L + +Y+++ DR E E + L
Sbjct: 1429 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 229 SDKLKEA-ETRAEFAERS------VTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
+ L+EA E + EF ++ + L S DD+ + V ++ ++ Q +++ +L
Sbjct: 1489 ARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQL 1548
Query: 282 NNM 284
+
Sbjct: 1549 EEL 1551
Score = 51.6 bits (122), Expect = 8e-07
Identities = 60/274 (21%), Positives = 123/274 (44%), Gaps = 17/274 (6%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAE--DRSKQLEEDIAAKEKLLRVSEDERDRV--- 60
K ++LK+ ++ E E ++K + + L E + A+ +L +E+ R R+
Sbjct: 857 KDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAK 916
Query: 61 ---LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQ-ERLATALQKLEE 115
LEE LH E + EE + + + IQ +EE+LD + R L+K+
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVT- 975
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR---KLVII 172
AE + E + ++E + K ++ ++ E ++ E + + K + +A+ K ++
Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 1035
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
SDLE ER + E ++LE+ R +D L + + D + ++ ++L
Sbjct: 1036 ISDLE---ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ A R + K + +L+ ++A +E+
Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQED 1126
Score = 51.6 bits (122), Expect = 8e-07
Identities = 46/261 (17%), Positives = 111/261 (42%), Gaps = 14/261 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
K L+ ++ + ++ K R +QLEE+ K L E+E E
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE---KNSLQEQQEEEE----EARK 1360
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
E +LA + A + V I+ +EE + + Q+LEE A D+
Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK--- 1417
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
+E + +++++ + L + +A + ++K ++ + L +S R E +
Sbjct: 1418 ----LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR 1473
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
+E + R+ E + + + L+ + A++++ ++ + +++ L + E+S
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKS 1533
Query: 246 VTKLEKSIDDLEEKVAHAKEE 266
LE+ ++++ ++ ++E
Sbjct: 1534 KRALEQQVEEMRTQLEELEDE 1554
Score = 48.1 bits (113), Expect = 9e-06
Identities = 42/188 (22%), Positives = 90/188 (47%), Gaps = 10/188 (5%)
Query: 20 DRAEQAEADKKAAEDRSKQ-------LEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL 72
+ E+ +++ + DR ++ L ++AA+ + S++ R + LE +K + L
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQ-LERQNKELKAKL 1801
Query: 73 AAEEAAAKAE--ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
E A K++ A +++L +I +EE+L++ + A A + + EK E ++
Sbjct: 1802 QELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDE 1861
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
A + +E+ME ++K+ K E+A+ + ++ +L+ A E E +V
Sbjct: 1862 RRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREV 1921
Query: 191 RQLEEQLR 198
L+ +LR
Sbjct: 1922 STLKNRLR 1929
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 24/150 (16%)
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
E KDEE ++++E Q K + E+ +RK++++ + I+ L
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGEL-EEMERKHQQLLEEKNILAEQL-------------- 896
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
Q E +L + ++A +AA K+ EE + L +++E E R + + K++
Sbjct: 897 -QAETELFAEAEEMRARLAA------KKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
Query: 251 KSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
I DLEE++ +EE L++ E
Sbjct: 950 AHIQDLEEQL--DEEEGARQKLQLEKVTAE 977
Score = 38.5 bits (88), Expect = 0.007
Identities = 44/219 (20%), Positives = 101/219 (46%), Gaps = 16/219 (7%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDS 70
L++D NA AE++ A K +++ +QLE + K L+ E + ++ KA S
Sbjct: 1764 LQVDTLNAELAAERSAAQK--SDNARQQLER----QNKELKAKLQELEGAVKSKFKATIS 1817
Query: 71 LLAA-----EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
L A EE + + A+ N+ ++ E++L ++ + ++ ++ +++
Sbjct: 1818 ALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANA 1877
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
MK ++ + ++ EE+ ++ + +DA E ++R++ +++ L R +
Sbjct: 1878 RMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRG---GPI 1934
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
S R QL + +L+ ++ +D S+ D E +
Sbjct: 1935 SFSSSRSGRRQLHLEGASLE--LSDDDTESKTSDVNETQ 1971
Score = 30.8 bits (68), Expect = 1.4
Identities = 20/91 (21%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
R EE + + ++ +++E+ ++ L+ + + ++++ E+++ ++ EAE
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEE 908
Query: 238 -RAEFAERSVTKLEKSIDDLEEKVAHAKEEN 267
RA A + +LE+ + DLE +V +E N
Sbjct: 909 MRARLAAKK-QELEEILHDLESRVEEEEERN 938
Score = 28.5 bits (62), Expect = 7.0
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+KK++ + + E+ A+Q + + A R KQL ++ L +E+E R
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQL-------KRQLEEAEEEATRANASR 1900
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQ 93
K + L A EA +V++L R++
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLR 1929
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 76.6 bits (187), Expect = 2e-14
Identities = 80/302 (26%), Positives = 142/302 (47%), Gaps = 33/302 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL--EEDIAAKEKLLRVSEDERDR 59
+A++ ++Q ++ ++ +L +AE AE K+ AE +++ E+ A +++ L E E+ R
Sbjct: 1640 EALRLRLQAEEVAQQKSLAQAE-AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1698
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
L E LAAE+ + A+ ++ QL+EEEL R Q A A QK +E E
Sbjct: 1699 QLAE--GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1756
Query: 120 ADESERGMKVI---------ESRAQKDEEKMEIQEIQLKEAKHIAEDADR---KYEEVAR 167
+ M+V+ ESR+ ++ K + E + + +AE+A R EE R
Sbjct: 1757 LAKVRAEMEVLLASKARAEEESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKR 1815
Query: 168 KLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV 227
+ + E D R AE R L E+L + + + AE +KE E ++
Sbjct: 1816 QRQLAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRL 1869
Query: 228 LSD------KLKE--AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
D +L+E A+ +A+ ER + +L K+ D E+ E+ L + +++ +L
Sbjct: 1870 AEDEAFQRRRLEEQAAQHKADIEER-LAQLRKASDSELERQKGLVEDTLRQRRQVEEEIL 1928
Query: 280 EL 281
L
Sbjct: 1929 AL 1930
Score = 69.7 bits (169), Expect = 3e-12
Identities = 78/310 (25%), Positives = 137/310 (44%), Gaps = 53/310 (17%)
Query: 21 RAEQAEADKKAAEDRSKQLEEDI-----------------------AAKEKL-------- 49
RAE+AEA K+ A++ +++L + AA+EK
Sbjct: 1481 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1540
Query: 50 LRVSEDERDRVLE--ELHKAEDSLLAAEEAAAKAEADV-----------ASLNRRIQLVE 96
LR+ +E +R L E+ +A +A E A AEA++ A L R +Q
Sbjct: 1541 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1600
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ + +E Q+ EAE+A +E+ER ++ + +A + ++ +Q ++ + K +A+
Sbjct: 1601 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA-NEALRLRLQAEEVAQQKSLAQ 1659
Query: 157 -DADRKYEEV---ARKLVIIESDLERAEERAELSEGQVRQLEE----QLRIMDQTLKALM 208
+A+++ EE AR+ E R E AE + RQL E Q +Q L L
Sbjct: 1660 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1719
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENL 268
A ++ Q+ EEE+ L + A + + E + K+ ++ L A A+EE+
Sbjct: 1720 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1779
Query: 269 SMHQMLDQTL 278
S + Q L
Sbjct: 1780 STSEKSKQRL 1789
Score = 65.5 bits (158), Expect = 5e-11
Identities = 75/289 (25%), Positives = 133/289 (46%), Gaps = 31/289 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEAD----KKAAED--RSKQLEEDIAAKEKLLRVSEDER 57
+++++ LK E A + E + + AED RSK+ E AA+++ L E+ R
Sbjct: 1923 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERR 1982
Query: 58 DRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEE---LDRAQERLATALQKLE 114
R EE + + SL A EEAA + +A + + R VEE +RA++ A LQ +
Sbjct: 1983 RREAEE--RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040
Query: 115 EA--EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
EA ++ E + ++ + Q+ ++ ++ ++ L + + AE A R EE V
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E + ++ + E +E + EEQ + Q A AAE K+ +
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQ---AQAAAE--------------KLRKEAE 2143
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
+EA RA+ AE++ + +++ D EK E+ L ++Q L L
Sbjct: 2144 QEAARRAQ-AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL 2191
Score = 64.7 bits (156), Expect = 9e-11
Identities = 76/300 (25%), Positives = 139/300 (46%), Gaps = 39/300 (13%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAED--RSKQLEEDIAAKEKLLRVSEDERDRVLE 62
+K Q L+ + + AE+A + AE+ R +QL E+ AA+++ E +RVL
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA------EAERVL- 1835
Query: 63 ELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEE--AEKAA 120
AE E K EA++A + + E L R E A ++LEE A+ A
Sbjct: 1836 ----AEKLAAIGEATRLKTEAEIALKEKEAE--NERLRRLAEDEAFQRRRLEEQAAQHKA 1889
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA---DRKYEEVARKLVIIESDLE 177
D ER ++ ++ + E + + E L++ + + E+ +E+ A +E +L
Sbjct: 1890 DIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELG 1949
Query: 178 R----------AEERAELSEGQVRQL----EEQLRIMDQTLKALMAAEDKYSQKEDRYEE 223
R ++E+AEL + RQL E + R ++ ++ +AAE++ +++ E
Sbjct: 1950 RIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE 2009
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM-----HQMLDQTL 278
E++ L K++EA E AE+ + + + +K A+E+ + Q L QTL
Sbjct: 2010 EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL 2069
Score = 64.3 bits (155), Expect = 1e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 32/285 (11%)
Query: 3 AIKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+I++++Q L+ E + +A QAEA AE ++EE+I L +E +R
Sbjct: 1417 SIQEELQQLRQSSEAEIQAKARQAEA----AERSRLRIEEEIRVVRLQLEATERQRGGAE 1472
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT------------- 108
EL AE +A+ + L R++Q + +A+ LA+
Sbjct: 1473 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1532
Query: 109 -ALQKLEEAEKAADESERGMKVIE-SRAQKDEEKMEI------QEIQLKEAKHIAEDA-- 158
ALQ LEE A+E+ER ++ E RA++ + +E E+Q K A + A
Sbjct: 1533 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1592
Query: 159 DRKYEEVARKLVIIESDLE-RAEERAELS---EGQVRQLEEQLRIMDQTLKALMAAEDKY 214
+R +E + + + E RA+++AE E R+LE ++ L+ + AE+
Sbjct: 1593 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652
Query: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
QK E K + +EA R + E++V + E + +LE++
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1697
Score = 63.5 bits (153), Expect = 2e-10
Identities = 59/289 (20%), Positives = 132/289 (45%), Gaps = 22/289 (7%)
Query: 13 LDKENALDRAE-QAEAD-KKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDS 70
L+K+ L A QA+A ++ A++ ++++E++ +E+ ++ ++ + EEL + S
Sbjct: 1369 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1428
Query: 71 -----------LLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
AAE + + E ++ + +++ E + A+ L + EEAE
Sbjct: 1429 SEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ 1488
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+++ + + + Q + ++ E++L +A R+ + + L + E A
Sbjct: 1489 KRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEA 1548
Query: 180 EERAELSE-GQVRQLEEQLRIMDQTLKALMAAE-----DKYSQKEDRYEEEIKVLSDKLK 233
E R +E + RQ++ L ++ +A + ++ +K +Q E +EE ++ +
Sbjct: 1549 ERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLRE 1608
Query: 234 EAETRAE---FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
EAE RA+ AER+ + E+ ++ + K A L ++ Q L
Sbjct: 1609 EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1657
Score = 63.5 bits (153), Expect = 2e-10
Identities = 65/297 (21%), Positives = 128/297 (43%), Gaps = 32/297 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K+KMQ ++ + AE + K+ A++++++L+ED KE++ + +E
Sbjct: 2312 LKEKMQAVQ-EATRLKAEAELLQQQKELAQEQARRLQED---KEQMAQQLAEETQGFQRT 2367
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L L A + + VA ++R EE+ R +++ +KL E A E
Sbjct: 2368 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEK 2427
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
++ +E + Q+ + E +L+EA E K ++ A+ L + +++ ++
Sbjct: 2428 VTLVQTLEIQRQQSDHDAE----RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ 2483
Query: 184 ELSEGQVRQLE----------------------EQLRIMDQTLKALMAAEDKYSQKEDRY 221
L E Q Q EQL D+ KA E++ Q++ +
Sbjct: 2484 LLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQL-FQDEVAKAQQLREEQQRQQQ-QM 2541
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
E+E + L ++EA R AE V + ++ + LE++ +E +Q L + L
Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2598
Score = 62.8 bits (151), Expect = 3e-10
Identities = 57/286 (19%), Positives = 131/286 (45%), Gaps = 18/286 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAE-ADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
A ++ + L+L +E A R + E A A + + ++L++ + ++ +L D++
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------DQLR 2080
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E A + AEEA +AE + A R+++ E A+E+ Q AEK
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2140
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E+E+ Q + + + ++++ K AE R+ +V ++L + LE +
Sbjct: 2141 EAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH 2200
Query: 182 RAELSEGQVRQLE-------EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
+ L + ++++L+ Q +++ L ++ ++ S+ + R E E + L L++
Sbjct: 2201 QKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI--LRD 2258
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
+ F + K+ K + + +++ A +E + Q+ ++ L +
Sbjct: 2259 KDNTQRFLQEEAEKM-KQVAEEAARLSVAAQEAARLRQLAEEDLAQ 2303
Score = 57.8 bits (138), Expect = 1e-08
Identities = 62/288 (21%), Positives = 130/288 (45%), Gaps = 33/288 (11%)
Query: 16 ENALDRAEQA-----EADKKAAED---RSKQLEEDIAAKEKLLRVSEDERDRVLEELHKA 67
E A R +QA E KK AE + Q+E+++ L ++ +++ + EEL +
Sbjct: 2153 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2212
Query: 68 EDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKL-------------E 114
+ A ++ E ++ S+ R+Q+ EEL + + R+ + L E
Sbjct: 2213 KAEATEAARQRSQVEEELFSV--RVQM--EELSKLKARIEAENRALILRDKDNTQRFLQE 2268
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
EAEK +E + + AQ+ ++ E L + + +AE ++ + ++ +++
Sbjct: 2269 EAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKA 2327
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTL-------KALMAAEDKYSQKEDRYEEEIKV 227
+ E +++ EL++ Q R+L+E M Q L + + AE + + E +K+
Sbjct: 2328 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKL 2387
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++ A+ RAE + K + I + + A +E +++ Q L+
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLE 2435
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/294 (20%), Positives = 124/294 (42%), Gaps = 32/294 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
DA + + + +L++E + E K+ E ++ Q E+ + + L + E+D +L
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ E E+ A L Q ++++++ ++RL + +EEA +
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS---MEEARRRQH 2560
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E+E G++ +K EE ++++ + ++ + +AE+ R E++ ++ E
Sbjct: 2561 EAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLREQLQ---LLEEQHRAALAH 2611
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E++ QV + D AE ++S R KV + +L+EA +
Sbjct: 2612 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRR----KVSAQRLQEAGILSAE 2667
Query: 242 AERSVTKLEKSIDDL--EEKVAH--------------AKEENLSMHQMLDQTLL 279
+ + + ++D+L E V H A E LS++ L + LL
Sbjct: 2668 ELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2721
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 76.6 bits (187), Expect = 2e-14
Identities = 80/302 (26%), Positives = 142/302 (47%), Gaps = 33/302 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL--EEDIAAKEKLLRVSEDERDR 59
+A++ ++Q ++ ++ +L +AE AE K+ AE +++ E+ A +++ L E E+ R
Sbjct: 1644 EALRLRLQAEEVAQQKSLAQAE-AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1702
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
L E LAAE+ + A+ ++ QL+EEEL R Q A A QK +E E
Sbjct: 1703 QLAE--GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1760
Query: 120 ADESERGMKVI---------ESRAQKDEEKMEIQEIQLKEAKHIAEDADR---KYEEVAR 167
+ M+V+ ESR+ ++ K + E + + +AE+A R EE R
Sbjct: 1761 LAKVRAEMEVLLASKARAEEESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKR 1819
Query: 168 KLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV 227
+ + E D R AE R L E+L + + + AE +KE E ++
Sbjct: 1820 QRQLAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRL 1873
Query: 228 LSD------KLKE--AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
D +L+E A+ +A+ ER + +L K+ D E+ E+ L + +++ +L
Sbjct: 1874 AEDEAFQRRRLEEQAAQHKADIEER-LAQLRKASDSELERQKGLVEDTLRQRRQVEEEIL 1932
Query: 280 EL 281
L
Sbjct: 1933 AL 1934
Score = 69.7 bits (169), Expect = 3e-12
Identities = 78/310 (25%), Positives = 137/310 (44%), Gaps = 53/310 (17%)
Query: 21 RAEQAEADKKAAEDRSKQLEEDI-----------------------AAKEKL-------- 49
RAE+AEA K+ A++ +++L + AA+EK
Sbjct: 1485 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1544
Query: 50 LRVSEDERDRVLE--ELHKAEDSLLAAEEAAAKAEADV-----------ASLNRRIQLVE 96
LR+ +E +R L E+ +A +A E A AEA++ A L R +Q
Sbjct: 1545 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1604
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ + +E Q+ EAE+A +E+ER ++ + +A + ++ +Q ++ + K +A+
Sbjct: 1605 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA-NEALRLRLQAEEVAQQKSLAQ 1663
Query: 157 -DADRKYEEV---ARKLVIIESDLERAEERAELSEGQVRQLEE----QLRIMDQTLKALM 208
+A+++ EE AR+ E R E AE + RQL E Q +Q L L
Sbjct: 1664 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1723
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENL 268
A ++ Q+ EEE+ L + A + + E + K+ ++ L A A+EE+
Sbjct: 1724 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1783
Query: 269 SMHQMLDQTL 278
S + Q L
Sbjct: 1784 STSEKSKQRL 1793
Score = 65.5 bits (158), Expect = 5e-11
Identities = 75/289 (25%), Positives = 133/289 (46%), Gaps = 31/289 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEAD----KKAAED--RSKQLEEDIAAKEKLLRVSEDER 57
+++++ LK E A + E + + AED RSK+ E AA+++ L E+ R
Sbjct: 1927 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERR 1986
Query: 58 DRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEE---LDRAQERLATALQKLE 114
R EE + + SL A EEAA + +A + + R VEE +RA++ A LQ +
Sbjct: 1987 RREAEE--RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044
Query: 115 EA--EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
EA ++ E + ++ + Q+ ++ ++ ++ L + + AE A R EE V
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2104
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E + ++ + E +E + EEQ + Q A AAE K+ +
Sbjct: 2105 EREAAQSRRQVEEAERLKQSAEEQAQARAQ---AQAAAE--------------KLRKEAE 2147
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
+EA RA+ AE++ + +++ D EK E+ L ++Q L L
Sbjct: 2148 QEAARRAQ-AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL 2195
Score = 64.7 bits (156), Expect = 9e-11
Identities = 76/300 (25%), Positives = 139/300 (46%), Gaps = 39/300 (13%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAED--RSKQLEEDIAAKEKLLRVSEDERDRVLE 62
+K Q L+ + + AE+A + AE+ R +QL E+ AA+++ E +RVL
Sbjct: 1787 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRA------EAERVL- 1839
Query: 63 ELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEE--AEKAA 120
AE E K EA++A + + E L R E A ++LEE A+ A
Sbjct: 1840 ----AEKLAAIGEATRLKTEAEIALKEKEAE--NERLRRLAEDEAFQRRRLEEQAAQHKA 1893
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA---DRKYEEVARKLVIIESDLE 177
D ER ++ ++ + E + + E L++ + + E+ +E+ A +E +L
Sbjct: 1894 DIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELG 1953
Query: 178 R----------AEERAELSEGQVRQL----EEQLRIMDQTLKALMAAEDKYSQKEDRYEE 223
R ++E+AEL + RQL E + R ++ ++ +AAE++ +++ E
Sbjct: 1954 RIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE 2013
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM-----HQMLDQTL 278
E++ L K++EA E AE+ + + + +K A+E+ + Q L QTL
Sbjct: 2014 EVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL 2073
Score = 64.3 bits (155), Expect = 1e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 32/285 (11%)
Query: 3 AIKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+I++++Q L+ E + +A QAEA AE ++EE+I L +E +R
Sbjct: 1421 SIQEELQQLRQSSEAEIQAKARQAEA----AERSRLRIEEEIRVVRLQLEATERQRGGAE 1476
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT------------- 108
EL AE +A+ + L R++Q + +A+ LA+
Sbjct: 1477 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1536
Query: 109 -ALQKLEEAEKAADESERGMKVIE-SRAQKDEEKMEI------QEIQLKEAKHIAEDA-- 158
ALQ LEE A+E+ER ++ E RA++ + +E E+Q K A + A
Sbjct: 1537 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1596
Query: 159 DRKYEEVARKLVIIESDLE-RAEERAELS---EGQVRQLEEQLRIMDQTLKALMAAEDKY 214
+R +E + + + E RA+++AE E R+LE ++ L+ + AE+
Sbjct: 1597 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1656
Query: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
QK E K + +EA R + E++V + E + +LE++
Sbjct: 1657 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1701
Score = 63.5 bits (153), Expect = 2e-10
Identities = 59/289 (20%), Positives = 132/289 (45%), Gaps = 22/289 (7%)
Query: 13 LDKENALDRAE-QAEAD-KKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDS 70
L+K+ L A QA+A ++ A++ ++++E++ +E+ ++ ++ + EEL + S
Sbjct: 1373 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1432
Query: 71 -----------LLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
AAE + + E ++ + +++ E + A+ L + EEAE
Sbjct: 1433 SEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ 1492
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+++ + + + Q + ++ E++L +A R+ + + L + E A
Sbjct: 1493 KRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEA 1552
Query: 180 EERAELSE-GQVRQLEEQLRIMDQTLKALMAAE-----DKYSQKEDRYEEEIKVLSDKLK 233
E R +E + RQ++ L ++ +A + ++ +K +Q E +EE ++ +
Sbjct: 1553 ERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLRE 1612
Query: 234 EAETRAE---FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
EAE RA+ AER+ + E+ ++ + K A L ++ Q L
Sbjct: 1613 EAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1661
Score = 63.5 bits (153), Expect = 2e-10
Identities = 65/297 (21%), Positives = 128/297 (43%), Gaps = 32/297 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K+KMQ ++ + AE + K+ A++++++L+ED KE++ + +E
Sbjct: 2316 LKEKMQAVQ-EATRLKAEAELLQQQKELAQEQARRLQED---KEQMAQQLAEETQGFQRT 2371
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L L A + + VA ++R EE+ R +++ +KL E A E
Sbjct: 2372 LEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEK 2431
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
++ +E + Q+ + E +L+EA E K ++ A+ L + +++ ++
Sbjct: 2432 VTLVQTLEIQRQQSDHDAE----RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQ 2487
Query: 184 ELSEGQVRQLE----------------------EQLRIMDQTLKALMAAEDKYSQKEDRY 221
L E Q Q EQL D+ KA E++ Q++ +
Sbjct: 2488 LLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQL-FQDEVAKAQQLREEQQRQQQ-QM 2545
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
E+E + L ++EA R AE V + ++ + LE++ +E +Q L + L
Sbjct: 2546 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQL 2602
Score = 62.8 bits (151), Expect = 3e-10
Identities = 57/286 (19%), Positives = 131/286 (45%), Gaps = 18/286 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAE-ADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
A ++ + L+L +E A R + E A A + + ++L++ + ++ +L D++
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------DQLR 2084
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E A + AEEA +AE + A R+++ E A+E+ Q AEK
Sbjct: 2085 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2144
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E+E+ Q + + + ++++ K AE R+ +V ++L + LE +
Sbjct: 2145 EAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDH 2204
Query: 182 RAELSEGQVRQLE-------EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
+ L + ++++L+ Q +++ L ++ ++ S+ + R E E + L L++
Sbjct: 2205 QKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI--LRD 2262
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
+ F + K+ K + + +++ A +E + Q+ ++ L +
Sbjct: 2263 KDNTQRFLQEEAEKM-KQVAEEAARLSVAAQEAARLRQLAEEDLAQ 2307
Score = 57.8 bits (138), Expect = 1e-08
Identities = 62/288 (21%), Positives = 130/288 (45%), Gaps = 33/288 (11%)
Query: 16 ENALDRAEQA-----EADKKAAED---RSKQLEEDIAAKEKLLRVSEDERDRVLEELHKA 67
E A R +QA E KK AE + Q+E+++ L ++ +++ + EEL +
Sbjct: 2157 EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRL 2216
Query: 68 EDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKL-------------E 114
+ A ++ E ++ S+ R+Q+ EEL + + R+ + L E
Sbjct: 2217 KAEATEAARQRSQVEEELFSV--RVQM--EELSKLKARIEAENRALILRDKDNTQRFLQE 2272
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
EAEK +E + + AQ+ ++ E L + + +AE ++ + ++ +++
Sbjct: 2273 EAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKA 2331
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTL-------KALMAAEDKYSQKEDRYEEEIKV 227
+ E +++ EL++ Q R+L+E M Q L + + AE + + E +K+
Sbjct: 2332 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKL 2391
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLD 275
++ A+ RAE + K + I + + A +E +++ Q L+
Sbjct: 2392 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLE 2439
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/294 (20%), Positives = 124/294 (42%), Gaps = 32/294 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
DA + + + +L++E + E K+ E ++ Q E+ + + L + E+D +L
Sbjct: 2448 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2507
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ E E+ A L Q ++++++ ++RL + +EEA +
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS---MEEARRRQH 2564
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E+E G++ +K EE ++++ + ++ + +AE+ R E++ ++ E
Sbjct: 2565 EAEEGVR------RKQEELQQLEQQRRQQEELLAEENQRLREQLQ---LLEEQHRAALAH 2615
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E++ QV + D AE ++S R KV + +L+EA +
Sbjct: 2616 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRR----KVSAQRLQEAGILSAE 2671
Query: 242 AERSVTKLEKSIDDL--EEKVAH--------------AKEENLSMHQMLDQTLL 279
+ + + ++D+L E V H A E LS++ L + LL
Sbjct: 2672 ELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLL 2725
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.122 0.293
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,263,880
Number of Sequences: 37866
Number of extensions: 378039
Number of successful extensions: 13371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 669
Number of HSP's successfully gapped in prelim test: 1009
Number of HSP's that attempted gapping in prelim test: 3089
Number of HSP's gapped (non-prelim): 5639
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.