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Search of human proteins with 63252904
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
(245 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 458 e-129
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 386 e-107
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 365 e-101
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 365 e-101
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 363 e-101
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 358 2e-99
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 348 3e-96
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 344 4e-95
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 339 1e-93
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 337 6e-93
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 328 3e-90
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 327 8e-90
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 321 4e-88
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 317 5e-87
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 308 2e-84
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 298 4e-81
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 239 1e-63
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 77 1e-14
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 74 1e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 72 4e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 72 4e-13
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 72 6e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 70 2e-12
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 69 4e-12
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 69 4e-12
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 69 4e-12
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 69 4e-12
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 69 4e-12
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 69 4e-12
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 69 4e-12
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 458 bits (1178), Expect = e-129
Identities = 245/245 (100%), Positives = 245/245 (100%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ
Sbjct: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL
Sbjct: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
Query: 241 ALNED 245
ALNED
Sbjct: 241 ALNED 245
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 386 bits (991), Expect = e-107
Identities = 202/244 (82%), Positives = 227/244 (93%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAG +++EAV+RKI+ LQ+QAD AEERA LQRE++ ER+ RE AEA+VASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
+ADRKYEEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
KED+YEEEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE++LY QLE+NR L+NELKL
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 ALNE 244
L++
Sbjct: 241 TLHD 244
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/157 (22%), Positives = 76/157 (48%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E +L+R +ER
Sbjct: 89 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 148
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
A K E E+ +K +E++A+K +K + E ++K ++A+ + E R
Sbjct: 149 LAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAER 208
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNL 168
+ +E ++ EER + L ELK ++L
Sbjct: 209 SVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 365 bits (938), Expect = e-101
Identities = 196/247 (79%), Positives = 222/247 (89%), Gaps = 3/247 (1%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAG +++EAV+RKI+ LQ+QAD AEERA LQRE++ ER+ RE AEA+VASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
+ADRKYEEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQN---RRLTNE 237
KED+YEEEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L E++ +R+ ++
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 238 LKLALNE 244
L LNE
Sbjct: 241 TLLDLNE 247
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 365 bits (936), Expect = e-101
Identities = 189/244 (77%), Positives = 220/244 (90%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAG +++EAV+RKI+ LQ+QAD AEERA LQRE++ ER+ RE AEA+VASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
+ADRKYEEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
KED+YEEEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE++LY QLE+NR L+NELKL
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 ALNE 244
L++
Sbjct: 241 TLHD 244
Score = 50.4 bits (119), Expect = 1e-06
Identities = 32/157 (20%), Positives = 75/157 (47%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E +L+R +ER
Sbjct: 89 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 148
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
A + E ++ ++ +K + + +K +K + E ++K ++A+ + E R
Sbjct: 149 LAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAER 208
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNL 168
+ +E ++ EER + L ELK ++L
Sbjct: 209 SVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 363 bits (933), Expect = e-101
Identities = 194/244 (79%), Positives = 218/244 (89%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAG +SLEAV+RKI++LQ+QAD AE+RA LQRELD ER+ RE AE DVA+LNRRIQLVE
Sbjct: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
+ADRKYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+
Sbjct: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
KED+YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L Q E+N L L
Sbjct: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Query: 241 ALNE 244
LNE
Sbjct: 241 TLNE 244
Score = 55.1 bits (131), Expect = 6e-08
Identities = 34/160 (21%), Positives = 77/160 (48%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E EL+RA+ER
Sbjct: 89 RGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAE 148
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
+ K + E+ +K +E+ ++K EK + E ++K ++A+ + E R
Sbjct: 149 VSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAER 208
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
+ +E ++ EE+ ++ + L + L N L +
Sbjct: 209 TVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 248
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 358 bits (920), Expect = 2e-99
Identities = 193/238 (81%), Positives = 210/238 (88%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED+LY Q + + ++ EL ALN+
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
Score = 60.8 bits (146), Expect = 1e-09
Identities = 35/160 (21%), Positives = 79/160 (49%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E +L+RA+ER
Sbjct: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
+ K E E+ +K +E++A+K +K + E ++K ++A+ + E R
Sbjct: 185 LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
+ +E ++ E+ + K + EEL N++ S+
Sbjct: 245 SVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
Score = 45.8 bits (107), Expect = 3e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 348 bits (892), Expect = 3e-96
Identities = 189/238 (79%), Positives = 205/238 (86%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
Score = 45.8 bits (107), Expect = 3e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 344 bits (883), Expect = 4e-95
Identities = 183/247 (74%), Positives = 215/247 (87%), Gaps = 3/247 (1%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
MAG +++EAV+RKI+ LQ+QAD AEERA LQRE++ ER+ RE AEA+VASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
+ADRKYEEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQN---RRLTNE 237
KED+YEEEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L E++ +R+ ++
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 238 LKLALNE 244
L LNE
Sbjct: 241 TLLDLNE 247
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 339 bits (869), Expect = 1e-93
Identities = 187/238 (78%), Positives = 200/238 (84%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
+ A + +R +++ D E + L + AEADVASLNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
Score = 44.7 bits (104), Expect = 7e-05
Identities = 28/104 (26%), Positives = 50/104 (48%)
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
+ + +K+ +++ D E A +RAE +E E+ K + ++ + E + DR
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
EE+ D L AE A AE V L + I +E++L + E+
Sbjct: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQER 105
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/179 (22%), Positives = 77/179 (43%), Gaps = 28/179 (15%)
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
+D ++++ E A A+++E K E R+++ EE + +E L+ ++ ++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE---DER 57
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
DR EE+ + E L AEE A +E A L ++ V
Sbjct: 58 DRVLEELHKA----EDSLLAAEEAAAKAEADVASLNRRIQLV------------------ 95
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
EEE+ ++L A + E AE++ + E+ + +E + + E+ +LK A
Sbjct: 96 ---EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 151
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 337 bits (864), Expect = 6e-93
Identities = 178/238 (74%), Positives = 204/238 (85%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L A+++K++ +++ D E Q +L+ K AEA+VASLNRRIQLVEEELDRA
Sbjct: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YE
Sbjct: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+LY Q + + ++ EL ALN+
Sbjct: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 281
Score = 58.5 bits (140), Expect = 5e-09
Identities = 35/160 (21%), Positives = 78/160 (48%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E +L+R +ER
Sbjct: 126 RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
A K E E+ +K +E++A+K +K + E ++K ++A+ + E R
Sbjct: 186 LAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAER 245
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
+ +E ++ E+ + K + EEL N++ S+
Sbjct: 246 SVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 328 bits (841), Expect = 3e-90
Identities = 177/238 (74%), Positives = 201/238 (84%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED+LY Q + + ++ EL ALN+
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/163 (21%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E +L+RA+ER
Sbjct: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
Query: 72 TA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 128
+ +++LEE + D++ + + E + + E++ E +EI++ K ++A+ + E
Sbjct: 185 LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE-EEIKVLSDK--LKEAETRAEF 241
Query: 129 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
R + +E ++ E+ + K + EEL N++ S+
Sbjct: 242 AERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 327 bits (837), Expect = 8e-90
Identities = 168/237 (70%), Positives = 202/237 (85%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+A+++K++ +++ + E Q +L+ K AEADVASLNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
EVARKLVI+E +LER+EERAE++E KC +LEEELK VTNNLKSLEAQA+KYS KED+YEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEE 223
Query: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EIK+L +KLKEAETRAEFAERSV KLEK+IDDLED++Y Q + + ++ EL ALN+
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALND 280
Score = 58.2 bits (139), Expect = 7e-09
Identities = 35/160 (21%), Positives = 78/160 (48%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E ++ + R++ ++E EL+R++ER
Sbjct: 125 RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 184
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
A K + E+ +K +E++A K K + E ++K + ++A+ + E R
Sbjct: 185 VAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAER 244
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
+ +E ++ E+ + K + EEL N++ SL
Sbjct: 245 SVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
Score = 57.0 bits (136), Expect = 1e-08
Identities = 35/111 (31%), Positives = 60/111 (54%), Gaps = 14/111 (12%)
Query: 127 EEVARKLVIIESDLERAEERAELSEG-------KCAELEEELKTVTNNLKSLEAQAEKYS 179
+ + +K+ +++ D E A +RAE +E +C +LEEE + + LK E + EKYS
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
E +K +KL++AE +A AE V L + I +E++L + E+
Sbjct: 62 -------ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQER 105
Score = 49.7 bits (117), Expect = 2e-06
Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 22/168 (13%)
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
+D ++++ E A A+++E K E R ++ EE+ + + +LK ED
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGT----EDE 56
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
KY E ++ + LE+AE++A +E A L ++ V L
Sbjct: 57 VEKYSESVKEA---QEKLEQAEKKATDAEADVASLNRRIQLVEEEL-------------- 99
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-KSIDDLEDQLYQQLE 229
DR +E + KL+EAE A+ +ER + +E +++ D E Q+++
Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQ 147
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 321 bits (822), Expect = 4e-88
Identities = 171/238 (71%), Positives = 198/238 (83%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L +++K++ +++ D E Q +L+ K AE DVA+LNRRIQLVEEELDRA
Sbjct: 43 LTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YE
Sbjct: 163 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L Q E+N L L LNE
Sbjct: 223 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 280
Score = 55.1 bits (131), Expect = 6e-08
Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 10/121 (8%)
Query: 127 EEVARKLVIIESDLERAEERAELSEG-------KCAELEEELKTVTNNLKSLEAQAEKYS 179
E + +K+ +++ D E A +RAE +E KC ++EEEL + LK E + +KYS
Sbjct: 2 EAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYS 61
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL---YQQLEQNRRLTN 236
+ +E++++ K +AE R + +E+ +D +++L Q+LE+ + +
Sbjct: 62 EDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
Query: 237 E 237
E
Sbjct: 122 E 122
Score = 55.1 bits (131), Expect = 6e-08
Identities = 34/160 (21%), Positives = 77/160 (48%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
R ++ ++ +A EE+ + +L + + E A+ + R++ ++E EL+RA+ER
Sbjct: 125 RGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAE 184
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
+ K + E+ +K +E+ ++K EK + E ++K ++A+ + E R
Sbjct: 185 VSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAER 244
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
+ +E ++ EE+ ++ + L + L N L +
Sbjct: 245 TVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/173 (21%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
++ +++++ + A+ + E+AE +E K +E ++K++ E +L +
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
+DA K E +K E D+ R +L +EEEL L + +
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQL-------VEEELDRAQERLATALQKL 113
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQL 228
E+ + D E +KV+ ++ + E + E E + K K I + D+ Y+++
Sbjct: 114 EEAEKAADESERGMKVIENRAMKDEEKMEIQEMQL-KEAKHIAEEADRKYEEV 165
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 317 bits (813), Expect = 5e-87
Identities = 173/238 (72%), Positives = 196/238 (82%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 308 bits (790), Expect = 2e-84
Identities = 171/238 (71%), Positives = 191/238 (80%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
+ A + +R +++ D E + L + AEADVASLNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 298 bits (762), Expect = 4e-81
Identities = 157/237 (66%), Positives = 190/237 (80%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+A+++K++ +++ + E Q +L+ K AEADVASLNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
EVARKLVI+E +LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
Query: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
EIK+L +KLKEAETRAEFAERSV KLEK+IDDLE+ L E+N + L L E
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 280
Score = 64.3 bits (155), Expect = 9e-11
Identities = 43/196 (21%), Positives = 99/196 (50%), Gaps = 7/196 (3%)
Query: 51 SLNRRIQLV----EEELDRAQERLATALQKLEEAEKAADESE---RGMKVIESRAQKDEE 103
++ +++Q++ E +DRA++ A Q + ++ +E + + +K E +K E
Sbjct: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
Query: 104 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT 163
++ + +L++A+ A DA+ + R++ ++E +L+RA+ER + K E E+
Sbjct: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
Query: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQ 223
+K +E +A K +K + E ++K ++++ + E R + LE ++ E++
Sbjct: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
Query: 224 LYQQLEQNRRLTNELK 239
+ R+L EL+
Sbjct: 183 AEVAESRARQLEEELR 198
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 239 bits (611), Expect = 1e-63
Identities = 134/241 (55%), Positives = 172/241 (71%), Gaps = 17/241 (7%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
++A+++K++ L+ + A +RA E AEAD R + +EEE
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRA--------------EQAEADKKQAEDRCKQLEEEQQAL 46
Query: 67 QERLATA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Q++L ++K E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+D
Sbjct: 47 QKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 106
Query: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
RKYEEVARKLVI+E +LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED
Sbjct: 107 RKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKED 166
Query: 184 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALN 243
+YEEEIK+L +KLKEAETRAEFAERSV KLEK+IDDLE+ L E+N + L L
Sbjct: 167 KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 226
Query: 244 E 244
E
Sbjct: 227 E 227
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 77.0 bits (188), Expect = 1e-14
Identities = 54/237 (22%), Positives = 112/237 (47%), Gaps = 6/237 (2%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD----RAQE 68
K+R +E EE+ L+ ++ + K+RE E R Q +E + R +E
Sbjct: 331 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 390
Query: 69 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 128
++ +K+ E E+ E E M E + + EE+M+ QE +++ + + ++K E
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Query: 129 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 188
K+ E ++ EE+ EGK E E +++ ++ E + + +K EE+
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK 510
Query: 189 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
I+ + ++E E + E + + E+ + + E+++ +Q E+ R E++L E+
Sbjct: 511 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE--QEVRLRQQEE 565
Score = 63.5 bits (153), Expect = 2e-10
Identities = 57/221 (25%), Positives = 108/221 (48%), Gaps = 24/221 (10%)
Query: 31 LQRELDHERKLRETAEADVASL-------NRRIQLVEEELDRAQERLATALQKLEEAEKA 83
LQ E DH K ++ A + + NR Q EE++ R +E++ +K++E E+
Sbjct: 251 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
Query: 84 ADESERGMKVIESRAQKDEEKMEIQE---------IQLKEAKHIAEDADRKYEEVARKLV 134
E E M+ E + EEKM QE I+ E K ++ R+ EE ++
Sbjct: 311 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 370
Query: 135 IIESDLERAEERAEL--SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR-Y--EEEI 189
I +R E+ A++ E K E EE+++ + ++ Q EK ++E++ + EEE+
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIR---EQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 190 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
+ +K++ E + E+ + + E+ I + E+ + +Q E+
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/223 (23%), Positives = 110/223 (49%), Gaps = 13/223 (5%)
Query: 20 QADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV---EEELDRAQERLATALQK 76
Q + +ER +Q + E K+RE E + R+ +++ EE++ R +E + +K
Sbjct: 293 QEEKIQEREEKIQEQ---EEKIREQEE----KMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 77 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 136
+ E E+ E E+ ++ E + Q++E+ E ++ Q +EAK ++ K E K+
Sbjct: 346 IRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQEEKIREQ 402
Query: 137 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 196
E ++ EE+ E K E EEE++ ++ E + + +K EE+I+ + +
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Query: 197 KEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+E E + E + + E + + E+++ +Q E+ R +++
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Score = 62.4 bits (150), Expect = 3e-10
Identities = 52/223 (23%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E R++ ++EQ E+ A ++E K+RE E + +Q EE++ +
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQE----EKIREQEEK-IREQEEMMQEQEEKMGEQE 417
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
E++ ++++E E+ E ++ E + ++ EEK+ QE ++E + + + K
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
E K+ E + R EE+ E K E EE+++ E + Q+E +E+
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR---------EQEEMMQEQEEKMWEQ 528
Query: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
E +K+ E E + + E + + E+ + + E +L QQ E+
Sbjct: 529 E-----EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 60.8 bits (146), Expect = 1e-09
Identities = 56/240 (23%), Positives = 116/240 (48%), Gaps = 17/240 (7%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E ++ K LQE+ E +Q L+ + R+ A + +++Q + L +
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQ--LNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 68 ERLATALQ-KLEEAE---KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
+ ++ LQ ++EE E + + E M E + Q+ EEK++ QE +++E E+
Sbjct: 263 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ----EEKM 318
Query: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL--KTVTNNLKSLEAQAEKYSQK 181
R+ EE+ + E + R EE E K ELEE++ + + + EK ++
Sbjct: 319 RRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 182 EDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
E R E+E K+ +K++E E + E + + E+ + + E+++++Q E+ + +++
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Score = 60.8 bits (146), Expect = 1e-09
Identities = 45/221 (20%), Positives = 103/221 (46%), Gaps = 3/221 (1%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L++V K+++ E+ + + ++ + + + E + +I+ EE++ R
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
+E + +K+ E+ E E ++ +E + ++EK+ QE + +E + I E R+
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQE 380
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
+E K+ E + EE+ E E EE++ + E + ++ +K R E
Sbjct: 381 QEA--KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQ 227
E+I+ K++E E + E + + E+ + + E ++ +Q
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Score = 58.5 bits (140), Expect = 5e-09
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 14/186 (7%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR +E EE+ G + E K+ E E +Q EE++ R +E++
Sbjct: 398 KIREQEEMMQEQEEKMG------EQEEKMWEQEE--------EMQEQEEKMRRQEEKIRE 443
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
+K+ E E+ E E M+ E + + E KM QE +++E + + K E +K
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Query: 133 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 192
+ E + EE + E K E EE++ ++ E + + +K E ++
Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Query: 193 SDKLKE 198
+K++E
Sbjct: 564 EEKMQE 569
Score = 57.8 bits (138), Expect = 9e-09
Identities = 47/219 (21%), Positives = 98/219 (44%), Gaps = 26/219 (11%)
Query: 11 RRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERL 70
+ KIR QE+ EE+ ++ + E K+ E + +I+ EE + +E++
Sbjct: 356 QEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEEMMQEQEEKM 413
Query: 71 ATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA 130
+K+ E E+ E E M+ E + ++ E+K+ QE +++E + + ++ + K E
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 131 RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA----------------- 173
K+ E+ ++ EE+ E K E E++++ ++ E
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 174 -QAEKYSQKEDRY-EEEIKVLSDKLKEAETRAEFAERSV 210
Q EK ++E++ +E +K++E E R E +
Sbjct: 534 EQEEKMQEQEEKMRRQE-----EKMREQEVRLRQQEEKM 567
Score = 56.2 bits (134), Expect = 2e-08
Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 8 EAVRRKIRSLQEQADAA---EERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
E +R + +QEQ + EE+ + E+ + + E + ++I+ EE++
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 124
+E + +K+ E E E E M+ E + ++ EEK+ QE +++E + + +
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY 178
+E K+ E + EE+ + E K EE+++ L+ E + +++
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 38.9 bits (89), Expect = 0.004
Identities = 45/262 (17%), Positives = 106/262 (40%), Gaps = 65/262 (24%)
Query: 16 SLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQ 75
S +++ A+ + L+REL+ + + L + + + + + +
Sbjct: 94 SPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 153
Query: 76 KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR---- 131
+L ++ K A E E+ + + ++ +K ADR EE+ +
Sbjct: 154 RLHDSWKFAGELEQALSAVATQKKK---------------------ADRYIEELTKERDA 192
Query: 132 ------------------------KLVIIES----------DLERAEERAEL------SE 151
KL ++ES +L+R ERA+L +
Sbjct: 193 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 252
Query: 152 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 211
+ L +EL++V+ L++ + E +++ + EE++ +K++E E + + E +
Sbjct: 253 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR 312
Query: 212 KLEKSIDDLEDQLYQQLEQNRR 233
+ E+ + E+ ++++ E+ RR
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRR 334
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 73.9 bits (180), Expect = 1e-13
Identities = 61/213 (28%), Positives = 112/213 (52%), Gaps = 28/213 (13%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDH--ERKLRETAEADVASLNRRIQLVEEELDR 65
EA R+ R LQE+ EER + REL E +LRE +A AS+ ++L EEE R
Sbjct: 369 EAQRQAERLLQEE----EERRRSQHRELQQALEGQLREAEQAR-ASMQAEMELKEEEAAR 423
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 125
++R+ ++LEE ++ E+ + +E +A++DEE + I + +L E +
Sbjct: 424 QRQRI----KELEEMQQRLQEALQ----LEVKARRDEESVRIAQTRLLEEE--------- 466
Query: 126 YEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRY 185
EE ++L+ ++ + ER ERA+ + EL++E+ + +L+ + Q E+ Q R
Sbjct: 467 -EEKLKQLMQLKEEQERYIERAQQEK---EELQQEMAQQSRSLQQAQQQLEEVRQNRQRA 522
Query: 186 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 218
+E+++ KL++A T + + +L I+
Sbjct: 523 DEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIE 555
Score = 53.9 bits (128), Expect = 1e-07
Identities = 55/229 (24%), Positives = 105/229 (45%), Gaps = 21/229 (9%)
Query: 16 SLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQ 75
+++ QA+ L+++ +R+ RE A R+Q ++EE +R + L +
Sbjct: 310 AIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQE 369
Query: 76 KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH----IAEDADRKYEEVAR 131
+AE+ E E E R + E + E QL+EA+ + + + K EE AR
Sbjct: 370 AQRQAERLLQEEE------ERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAAR 423
Query: 132 ---KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 188
++ +E +R +E +L E K EE ++ L LE + EK Q EE+
Sbjct: 424 QRQRIKELEEMQQRLQEALQL-EVKARRDEESVRIAQTRL--LEEEEEKLKQLMQLKEEQ 480
Query: 189 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNE 237
+ ++ A+ E ++ + + +S+ + QL +++ QNR+ +E
Sbjct: 481 ERY----IERAQQEKEELQQEMAQQSRSLQQAQQQL-EEVRQNRQRADE 524
Score = 45.8 bits (107), Expect = 3e-05
Identities = 38/177 (21%), Positives = 78/177 (44%), Gaps = 16/177 (9%)
Query: 79 EAEKAADESE--RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 136
E +AA E E R ++ E + +K +E +QE Q + + + E+ +R+ + +
Sbjct: 337 ERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQAL 396
Query: 137 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ------KEDRYEEEIK 190
E L AE+ + + EEE +K LE ++ + K R EE ++
Sbjct: 397 EGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVR 456
Query: 191 VL--------SDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+ +KLK+ E ER + + ++ ++L+ ++ QQ ++ +L+
Sbjct: 457 IAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLE 513
Score = 33.1 bits (74), Expect = 0.23
Identities = 21/121 (17%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE---ELD 64
EA++ ++++ +++ + L+ E + ++L + E + R Q EE E+
Sbjct: 440 EALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMA 499
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 124
+ L A Q+LEE + ++ ++ + + ++ ++ +Q+ H E D+
Sbjct: 500 QQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDK 559
Query: 125 K 125
+
Sbjct: 560 R 560
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 4e-13
Identities = 52/225 (23%), Positives = 110/225 (48%), Gaps = 16/225 (7%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR +++ EE+ + ++ + + E + + +IQ EEE+ R +E++
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR- 398
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
++ E+ ++ E+ M+ + + ++ EE+M QE +++E + + +D + K EV K
Sbjct: 399 --EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 133 LVIIESDLERAEERAELSEGKCAELEEEL----KTVTNNLKSLEAQAEKYSQKEDRYEEE 188
+ E ++ EE+ + E K E EE+ K + K E + + + Q+E +E+E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 189 IKV---------LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
K+ +K++E E R E + + E + +LE++L
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 67.4 bits (163), Expect = 1e-11
Identities = 56/257 (21%), Positives = 117/257 (45%), Gaps = 24/257 (9%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKL--RETAEADVASLNRRIQLVEEELD--- 64
++ K+R ++ + + L+R+L+ + L ++ + + L + +Q V +L
Sbjct: 223 LQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 65 -----------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
+ +E++ +K++E E+ E E ++ E + + EEKM QE +++
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 173
E + + K E K+ E + R EE+ + K E EEE+ + +
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM---WRQEEKIRE 399
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQ-----QL 228
Q EK +K R E++++ +K++E E E + +LE+ + D E++L + Q
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 229 EQNRRLTNELKLALNED 245
E+ + E K+ E+
Sbjct: 460 EEEKMQEQEEKIQRQEE 476
Score = 65.1 bits (157), Expect = 5e-11
Identities = 46/203 (22%), Positives = 107/203 (52%), Gaps = 6/203 (2%)
Query: 32 QRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 91
++ + E K+RE E + ++ EE++ ++++ +K+ E E+ E E M
Sbjct: 311 EKMCEQELKIREQEEK-MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 92 KVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE-- 148
E + ++ +EK++ QE ++ ++ + I E +++ E++ R+ + E+ E+ E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 149 -LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 207
E K ELEE ++ L+ +E + ++ +K EE+I+ +K++E E + + +
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQ 488
Query: 208 RSVTKLEKSIDDLEDQLYQQLEQ 230
+ K E+ I + E+++++Q E+
Sbjct: 489 EKLLKQEEKIWEQEEKMWRQEEK 511
Score = 64.7 bits (156), Expect = 7e-11
Identities = 50/208 (24%), Positives = 106/208 (50%), Gaps = 12/208 (5%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E + R+ ++EQ + +E+ + R+ + R+ E + + ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE--IQLKEAKHIAEDADRK 125
E + +K+ E E+ + E ++ +E + Q++EEKM+ QE IQ +E K I E ++
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK-IQEQEEKT 485
Query: 126 YEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRY 185
+ + KL+ E + EE+ E K E EE+++ + ++ Q EK ++E R
Sbjct: 486 WRQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ---EQEEKMQRQEEKMREQEVRL 540
Query: 186 EEEIKVLSDKLKEAETRAEFAERSVTKL 213
++ +K++E E R + E + KL
Sbjct: 541 WQQ----EEKMQEQEVRLQELEERLGKL 564
Score = 64.3 bits (155), Expect = 9e-11
Identities = 57/248 (22%), Positives = 115/248 (46%), Gaps = 19/248 (7%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQREL-DHERKLRETAEADVASLNRRIQLVEEELDRA 66
E ++ K LQE+ E +Q + D +RKL A + +++Q+ + L +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER---AQLLLPQQQLQVEADRLGKE 270
Query: 67 QERLATALQ-KLEEAEK---AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
+ ++ LQ ++EE E + E M E + Q+ EEKM QE++++E +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----------KTVTNNLKSL 171
+ K E K+ E + R EE+ E K E EE++ + + + +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQN 231
Q EK ++E++ +E++ K++E + + E + + E+ I +LE+ + Q E+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 232 RRLTNELK 239
R + +++
Sbjct: 451 REVEEKMQ 458
Score = 64.3 bits (155), Expect = 9e-11
Identities = 51/228 (22%), Positives = 107/228 (46%), Gaps = 10/228 (4%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR +E+ EE+ + ++ + E + +I+ EE++ R +E++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEE 128
+K++E E+ E ++ E + Q + E+KM Q+ +++E + + K E
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 129 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE----AQAEKYSQKEDR 184
+ + E L EE+ + E K E EE+++ ++ E Q + Q+E
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 185 YEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
+E+E K+ +K+ E E + + E + + E+ + + E +L+QQ E+
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Score = 63.9 bits (154), Expect = 1e-10
Identities = 53/183 (28%), Positives = 89/183 (48%), Gaps = 8/183 (4%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR L+E EE+ ++ ++ E + + E + +IQ EE+ R QE+L
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLK 493
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
+K+ E E+ E M E + Q+ EEKM+ QE +++E + + K +E +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 133 LVIIESDLERAEERAELSEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEE 187
L +E L + ++AEL G E + L T+T LKS EAQ+ Q++D Y
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRG 611
Query: 188 EIK 190
++
Sbjct: 612 HLQ 614
Score = 39.3 bits (90), Expect = 0.003
Identities = 45/204 (22%), Positives = 94/204 (46%), Gaps = 37/204 (18%)
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 125
AQ+R +L LEE G + + ++D +E+ + + E+ K
Sbjct: 167 AQKRPENSL--LEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITD-----EELKEK 219
Query: 126 YEEVARKLVIIES----------DLERAEERAEL------SEGKCAELEEELKTVTNNLK 169
E+ KL ++ES DL+R ERA+L + + L +EL++V+ L+
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 170 SL-----------EAQAEKYSQKEDRYEEEIKVLSD---KLKEAETRAEFAERSVTKLEK 215
+ + Q EK ++E++ +E+ + + + K++E E + E + + E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 216 SIDDLEDQLYQQLEQNRRLTNELK 239
I + ED++++Q E+ R +++
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIR 363
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 4e-13
Identities = 52/225 (23%), Positives = 110/225 (48%), Gaps = 16/225 (7%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR +++ EE+ + ++ + + E + + +IQ EEE+ R +E++
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR- 398
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
++ E+ ++ E+ M+ + + ++ EE+M QE +++E + + +D + K EV K
Sbjct: 399 --EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 133 LVIIESDLERAEERAELSEGKCAELEEEL----KTVTNNLKSLEAQAEKYSQKEDRYEEE 188
+ E ++ EE+ + E K E EE+ K + K E + + + Q+E +E+E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 189 IKV---------LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
K+ +K++E E R E + + E + +LE++L
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 67.4 bits (163), Expect = 1e-11
Identities = 56/257 (21%), Positives = 117/257 (45%), Gaps = 24/257 (9%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKL--RETAEADVASLNRRIQLVEEELD--- 64
++ K+R ++ + + L+R+L+ + L ++ + + L + +Q V +L
Sbjct: 223 LQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 65 -----------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
+ +E++ +K++E E+ E E ++ E + + EEKM QE +++
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 173
E + + K E K+ E + R EE+ + K E EEE+ + +
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM---WRQEEKIRE 399
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQ-----QL 228
Q EK +K R E++++ +K++E E E + +LE+ + D E++L + Q
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 229 EQNRRLTNELKLALNED 245
E+ + E K+ E+
Sbjct: 460 EEEKMQEQEEKIQRQEE 476
Score = 65.1 bits (157), Expect = 5e-11
Identities = 46/203 (22%), Positives = 107/203 (52%), Gaps = 6/203 (2%)
Query: 32 QRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 91
++ + E K+RE E + ++ EE++ ++++ +K+ E E+ E E M
Sbjct: 311 EKMCEQELKIREQEEK-MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 92 KVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE-- 148
E + ++ +EK++ QE ++ ++ + I E +++ E++ R+ + E+ E+ E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 149 -LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 207
E K ELEE ++ L+ +E + ++ +K EE+I+ +K++E E + + +
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQ 488
Query: 208 RSVTKLEKSIDDLEDQLYQQLEQ 230
+ K E+ I + E+++++Q E+
Sbjct: 489 EKLLKQEEKIWEQEEKMWRQEEK 511
Score = 64.7 bits (156), Expect = 7e-11
Identities = 50/208 (24%), Positives = 106/208 (50%), Gaps = 12/208 (5%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E + R+ ++EQ + +E+ + R+ + R+ E + + ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE--IQLKEAKHIAEDADRK 125
E + +K+ E E+ + E ++ +E + Q++EEKM+ QE IQ +E K I E ++
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK-IQEQEEKT 485
Query: 126 YEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRY 185
+ + KL+ E + EE+ E K E EE+++ + ++ Q EK ++E R
Sbjct: 486 WRQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ---EQEEKMQRQEEKMREQEVRL 540
Query: 186 EEEIKVLSDKLKEAETRAEFAERSVTKL 213
++ +K++E E R + E + KL
Sbjct: 541 WQQ----EEKMQEQEVRLQELEERLGKL 564
Score = 64.3 bits (155), Expect = 9e-11
Identities = 57/248 (22%), Positives = 115/248 (46%), Gaps = 19/248 (7%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQREL-DHERKLRETAEADVASLNRRIQLVEEELDRA 66
E ++ K LQE+ E +Q + D +RKL A + +++Q+ + L +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER---AQLLLPQQQLQVEADRLGKE 270
Query: 67 QERLATALQ-KLEEAEK---AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
+ ++ LQ ++EE E + E M E + Q+ EEKM QE++++E +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----------KTVTNNLKSL 171
+ K E K+ E + R EE+ E K E EE++ + + + +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQN 231
Q EK ++E++ +E++ K++E + + E + + E+ I +LE+ + Q E+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 232 RRLTNELK 239
R + +++
Sbjct: 451 REVEEKMQ 458
Score = 64.3 bits (155), Expect = 9e-11
Identities = 51/228 (22%), Positives = 107/228 (46%), Gaps = 10/228 (4%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR +E+ EE+ + ++ + E + +I+ EE++ R +E++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEE 128
+K++E E+ E ++ E + Q + E+KM Q+ +++E + + K E
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 129 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE----AQAEKYSQKEDR 184
+ + E L EE+ + E K E EE+++ ++ E Q + Q+E
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Query: 185 YEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
+E+E K+ +K+ E E + + E + + E+ + + E +L+QQ E+
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Score = 63.9 bits (154), Expect = 1e-10
Identities = 53/183 (28%), Positives = 89/183 (48%), Gaps = 8/183 (4%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
KIR L+E EE+ ++ ++ E + + E + +IQ EE+ R QE+L
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLK 493
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
+K+ E E+ E M E + Q+ EEKM+ QE +++E + + K +E +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 133 LVIIESDLERAEERAELSEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEE 187
L +E L + ++AEL G E + L T+T LKS EAQ+ Q++D Y
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRG 611
Query: 188 EIK 190
++
Sbjct: 612 HLQ 614
Score = 38.5 bits (88), Expect = 0.005
Identities = 45/204 (22%), Positives = 94/204 (46%), Gaps = 37/204 (18%)
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 125
AQ+R +L LEE G + + ++D +E+ + + E+ K
Sbjct: 167 AQKRPENSL--LEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITD-----EELKEK 219
Query: 126 YEEVARKLVIIES----------DLERAEERAEL------SEGKCAELEEELKTVTNNLK 169
E+ KL ++ES DL+R ERA+L + + L +EL++V+ L+
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 170 SL-----------EAQAEKYSQKEDRYEEEIKVLSD---KLKEAETRAEFAERSVTKLEK 215
+ + Q EK ++E++ +E+ + + + K++E E + E + + E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 216 SIDDLEDQLYQQLEQNRRLTNELK 239
I + ED++++Q E+ R +++
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIR 363
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 71.6 bits (174), Expect = 6e-13
Identities = 60/255 (23%), Positives = 138/255 (54%), Gaps = 26/255 (10%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEER-AGTLQRELDHERKLRETAEADVASLNRRIQLVEEE 62
+++++ +++ L++QA + + A TLQ++ + LR E +SL ++ Q ++E
Sbjct: 511 NATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEV 570
Query: 63 LDRAQ-------ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-- 113
++ + ++LATA EE E + E + +K +E+ ++ K+EI + QL+
Sbjct: 571 AEKQEATRQDHAQQLATAA---EEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVA 627
Query: 114 -EAKHIAE----DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNL 168
EA+ A+ A R+ E++RK+ +++ +E A + ++ + AELE +L++
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSE---- 683
Query: 169 KSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER----SVTKLEKSIDDLEDQL 224
+ + E+ +Q++D+ +E+++ L + LK + E +R ++ + ++ I +L+ +
Sbjct: 684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET 743
Query: 225 YQQLEQNRRLTNELK 239
+EQ++R EL+
Sbjct: 744 RSLVEQHKRERKELE 758
Score = 62.4 bits (150), Expect = 3e-10
Identities = 58/250 (23%), Positives = 116/250 (46%), Gaps = 27/250 (10%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
LEA+R ++ L++Q +E+A +L+R L+ ER R ++ + +L +++ +EL +
Sbjct: 1122 LEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHS 1181
Query: 67 QERLATALQ-------KLEEAEKAADESE----RGMKVIE---SRAQKDEEKMEI----- 107
Q LA+A + K+++ KA DE + RG + E S EE++ I
Sbjct: 1182 QSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQV 1241
Query: 108 --QEIQLKEAKHIAEDADRKYEEVARKLVIIE----SDLERAEERAELSEGKCAELEEEL 161
+E + KE K + K +++ +L +++ S+ RA ER+ + L EE
Sbjct: 1242 LEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEA 1301
Query: 162 KTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDL- 220
+ ++L + +++ + +E+K +K + E + T + + +L
Sbjct: 1302 EKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Query: 221 -EDQLYQQLE 229
L QQL+
Sbjct: 1362 PAKHLCQQLQ 1371
Score = 52.8 bits (125), Expect = 3e-07
Identities = 53/258 (20%), Positives = 112/258 (43%), Gaps = 31/258 (12%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRI----QLVEEELDR 65
+R+K+ + A + +L +K + L R Q +E ELD+
Sbjct: 1412 LRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQ 1471
Query: 66 AQERL--------ATALQKLEEAEKAADESERGM------------KVIESRAQKDEEKM 105
A+E+ A A +L E ++ A + R + KV+E R + EE+
Sbjct: 1472 AREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQ 1531
Query: 106 EIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVT 165
++ Q+++ + + ++ EE+++KL + + +++ + + + E ++E + +
Sbjct: 1532 KLTA-QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQ 1590
Query: 166 NNLKSLEAQAEKYSQKEDRYE---EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE- 221
L L+AQ + Q + Y+ E+ K D K+ + RS+ +L+K +L
Sbjct: 1591 AQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRA 1650
Query: 222 --DQLYQQLEQNRRLTNE 237
++L +L+Q T E
Sbjct: 1651 EAERLGHELQQAGLKTKE 1668
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/280 (21%), Positives = 119/280 (42%), Gaps = 57/280 (20%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQ--------- 57
L+ + ++R L++Q L+ EL RKL +A +A + +RI
Sbjct: 209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQ 268
Query: 58 ----LVEEELDRAQERLATALQKLEEAEKAA-----DESERGMKVIESRAQKDEEKMEIQ 108
L +EL+ +++ + +L E K ++S+ K+ + + + +++
Sbjct: 269 AASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLR 328
Query: 109 EI-----QLKEA-KHIAEDADRKYEEVARKLVIIESDLERA-------EERAELSEGKCA 155
E QL++A + E+ + +E K +E +L A EE+ E+ +GK +
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLS 388
Query: 156 ELEEELKTVTNN--------------LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 201
+LEE L + +N L++L+ +A + + + +++L + + E
Sbjct: 389 QLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEA 448
Query: 202 -----RAEFAERS------VTKLEKSIDDLEDQLYQQLEQ 230
R F E +T L+ SI +L Q ++LEQ
Sbjct: 449 KLLAERGHFEEEKQQLSSLITDLQSSISNL-SQAKEELEQ 487
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/214 (22%), Positives = 98/214 (45%), Gaps = 17/214 (7%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
++ LE ++++++ E D+A+ QRE + E +A V + + + ++
Sbjct: 614 AAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQV 673
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
+ +L + QK E E+ A E ++ ++ + Q +E +++ + L+E K A DA
Sbjct: 674 AELELQLRSEQQKATEKERVAQEKDQ----LQEQLQALKESLKVTKGSLEEEKRRAADAL 729
Query: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
+ + +L +AE R+ + + K +EL+ K LEA+ + Q +
Sbjct: 730 EEQQRCISEL--------KAETRSLVEQHK--RERKELEEERAGRKGLEARLQ---QLGE 776
Query: 184 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 217
++ E +VL +L EA AE +L K +
Sbjct: 777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEV 810
Score = 47.4 bits (111), Expect = 1e-05
Identities = 43/227 (18%), Positives = 95/227 (41%), Gaps = 13/227 (5%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+A + ++ L AE R +QRE + E A ++ EE R Q
Sbjct: 1471 QAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVL---EERQRFQ 1527
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
E ++E+ E E + ++ + + ++ ++Q+ +LK + ++ ++ +
Sbjct: 1528 EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ 1587
Query: 128 EVARKLVIIESDLERAEERAE-----LSEGKC-----AELEEELKTVTNNLKSLEAQAEK 177
+ +L +++ L + E+ AE + + K + +EL+ +L+ L+ + ++
Sbjct: 1588 RLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKE 1647
Query: 178 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
+ +R E++ K KEAE V LE + + QL
Sbjct: 1648 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1694
Score = 45.8 bits (107), Expect = 3e-05
Identities = 61/262 (23%), Positives = 111/262 (42%), Gaps = 37/262 (14%)
Query: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
AG LEA LQ+ +A + L+REL + TAE++ L + + E
Sbjct: 762 AGRKGLEA------RLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRE 815
Query: 62 ELDRA-----------QERLATALQKLEEAEKAADESERGMKVIESRA--QKDEEKMEIQ 108
+ + QE+L T ++ E+A + E++ + IES + Q ++ E+
Sbjct: 816 RYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELA 875
Query: 109 EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE-------EEL 161
E+ A+ + + ++ E A+KL DL +E+ + + A LE E+
Sbjct: 876 ELHANLARALQQVQEK--EVRAQKLA---DDLSTLQEKMAATSKEVARLETLVRKAGEQQ 930
Query: 162 KTVTNNL-----KSLEAQAEKYSQKEDR-YEEEIKVLSDKLKEAETRAEFAERSVTKLEK 215
+T + L ++ + Q E +++ R + L +EAE ER L +
Sbjct: 931 ETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALME 990
Query: 216 SIDDLEDQLYQQLEQNRRLTNE 237
S +++ QQ + RLT E
Sbjct: 991 SQGQQQEERGQQEREVARLTQE 1012
Score = 43.9 bits (102), Expect = 1e-04
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 25/223 (11%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E R + ++ Q EER G +RE+ + R A+AD+A +E L A
Sbjct: 980 ELERLRAALMESQGQQQEER-GQQEREVARLTQERGRAQADLALEKAARAELEMRLQNAL 1038
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
L+EA A + G KD+E +++ ++ + K + E
Sbjct: 1039 NEQRVEFATLQEALAHALTEKEG---------KDQELAKLRGLEAAQIKEL--------E 1081
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
E+ + + ++ L + E+ G +E + L++L A+ K Q+ + +E
Sbjct: 1082 ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQE 1141
Query: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
+ L L EAE RA AER + +++ L+ QL ++ ++
Sbjct: 1142 QADSLERSL-EAE-RASRAER-----DSALETLQGQLEEKAQE 1177
Score = 42.0 bits (97), Expect = 5e-04
Identities = 56/258 (21%), Positives = 103/258 (39%), Gaps = 30/258 (11%)
Query: 6 SLEAVRRKIRSLQEQADAAEERA--GTLQRELDHERKLRETAEADVASLN--RRIQLVE- 60
+LE R ++ Q E+R TLQ L H +E + ++A L Q+ E
Sbjct: 1021 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL 1080
Query: 61 EELDRAQERLATALQKLE---------EAEKAADESERGMKV---------IESRAQKDE 102
EEL + ++L L K E ++E A G K+ +E + QK +
Sbjct: 1081 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ 1140
Query: 103 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 162
E+ + E L+ AE A R + A L ++ LE + S+ A + EL
Sbjct: 1141 EQADSLERSLE-----AERASRAERDSA--LETLQGQLEEKAQELGHSQSALASAQRELA 1193
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 222
++ +++ + R +E + + + E R V + E +L+
Sbjct: 1194 AFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKR 1253
Query: 223 QLYQQLEQNRRLTNELKL 240
+ + E++++L L+L
Sbjct: 1254 LVMAESEKSQKLEERLRL 1271
Score = 29.3 bits (64), Expect = 3.3
Identities = 43/224 (19%), Positives = 95/224 (42%), Gaps = 8/224 (3%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
L+AV+ + Q++A + + LQ +L + + E + + +++
Sbjct: 1572 LKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1631
Query: 67 QERLATALQKLEEAEKAADESER-GMKVIESRAQKDEEKMEIQEI--QLKEAKHIAEDAD 123
QE+L + Q +E ++ E+ER G ++ ++ + E + + + Q++ + AD
Sbjct: 1632 QEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHAD 1691
Query: 124 RKYEEVARKLV---IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
++ ++ + V ++S +A+ + +LS EE ++ K Q + S
Sbjct: 1692 QQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSV 1751
Query: 181 KEDRYEEEIKVLSDKLKEAETR--AEFAERSVTKLEKSIDDLED 222
+ + L K++ E+ RS LE S+D L D
Sbjct: 1752 PGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGD 1795
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 70.1 bits (170), Expect = 2e-12
Identities = 56/229 (24%), Positives = 114/229 (49%), Gaps = 13/229 (5%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEA--DVASLNRRIQLVEEELDR 65
E V R+ ++EQ + E+ + R+ E K+RE E + ++ + ++ EEE +
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQ---EEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 66 AQE-RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 124
QE ++ +K+ E E+ E ++ E + Q+ EEKM QE +++E + ++ +
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 184
K E K+ E + EE+ E K E EE+++ +++ Q EK ++E +
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ---EQEETMWRQEEKIREQEKK 683
Query: 185 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRR 233
E+ +K++E E + E + + E+ + + E+++ +Q E+ RR
Sbjct: 684 IREQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/241 (20%), Positives = 114/241 (47%), Gaps = 14/241 (5%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEA-DVASLNRRIQLV--EEELDRAQER 69
KIR +E+ E++ + ++ + K+RE + + + R+ + + +EE+ R +E+
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
Query: 70 LATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE-- 127
+ +K+ + E+ E ++ E + ++ EEKM QE +++E + + + ++ +E
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
Query: 128 ---------EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY 178
E K+ E + EE+ E K E EE+ + + E + +
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Query: 179 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
+K EE+I+ +K++E E + E + + E+ + + E+++ +Q E R ++
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 239 K 239
+
Sbjct: 678 R 678
Score = 62.4 bits (150), Expect = 3e-10
Identities = 60/248 (24%), Positives = 111/248 (44%), Gaps = 25/248 (10%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E +R + EQ E+ + E E++ R+ EA + +I+ EE++ +
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI-QLKEAKHIAEDADRKY 126
+++ +K+ E EK +E +R + E +++E+ E +EI + KE H E+ RK
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 127 EEVA----RKLVIIESDLERAEERAELSEGKCAELEE---------ELKTVTNNLKSLEA 173
EE K+ E + EE+ E K E EE E + + K E
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 174 QAEKYSQKED---------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
+ + + Q+E R EE+I+ +K +E E + E + + E+ I + E+++
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 225 YQQLEQNR 232
+Q E+ R
Sbjct: 629 REQEEKIR 636
Score = 62.0 bits (149), Expect = 5e-10
Identities = 52/234 (22%), Positives = 107/234 (45%), Gaps = 9/234 (3%)
Query: 12 RKIRSLQEQADAAEERAGTLQREL-DHERKLRETAEA-----DVASLNRRIQLVEEELDR 65
R+ + EQ EE Q E+ E K+ E E + +I+ EE++ R
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 125
+E++ +K+ E E+ E ++ E +++E+ E ++I +E + ED +
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 126 YEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRY 185
EE R+ E + R EE+ E K E EE++ ++ E + ++ +K
Sbjct: 575 QEEKIREQ---EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 186 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
EE+I+ + +E E + E + + E+ + + E+ +++Q E+ R +++
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
Score = 61.2 bits (147), Expect = 8e-10
Identities = 59/231 (25%), Positives = 109/231 (47%), Gaps = 25/231 (10%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLAT 72
K+R +E EE+ L+ ++ + K+RE E + EEE R QE+
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----------KRQEEEKIREQEKRQE 427
Query: 73 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE-IQLKEAKHIAEDADRKYEEV-- 129
K+ E+ E E ++ E + + EEK+ QE I+ +E + E+ R+ E++
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 130 -------ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
K+ E + + EE+ E K E EE+++ + + Q EK ++E
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR---EQEEKMWRQEEKIREQE 544
Query: 183 DRYEEEIKV-LSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNR 232
+ + EE K+ +K+ E E R E E + + E+ I + E+++++Q E+ R
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQE-QEDKMWRQEEKIREQEEKVWRQEEKIR 594
Score = 61.2 bits (147), Expect = 8e-10
Identities = 48/223 (21%), Positives = 102/223 (45%), Gaps = 7/223 (3%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E + R+ ++EQ + E ++E E + R+ E + +I+ EE++ R +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
E K+ E E+ E E M E + ++ EEK++ QE +++E + + + +
Sbjct: 591 E-------KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
E K+ E + EE+ + E EE+++ ++ E + + + EE
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Query: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
++ +K+ E E + + E + + E+ + + E +L QQ E+
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 60.1 bits (144), Expect = 2e-09
Identities = 51/204 (25%), Positives = 97/204 (47%), Gaps = 11/204 (5%)
Query: 31 LQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 90
LQ E DH K ++ A + + +L + +E++ +K++E E+ E E
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 91 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 150
++ E + ++ EEKM QE + E E+ R+ EE+ + E + R EE
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEK 375
Query: 151 EGKCAELEEELKTVTNNLKSLEA---QAEKYSQKEDRYEEEIKVL-SDKLKEAETRAEFA 206
E K EE + ++ LE + EK ++E++ +EE K+ +K +E E +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 207 ERSVTKLEKSIDDLEDQLYQQLEQ 230
E + + E+ I + E ++++Q E+
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEK 459
Score = 60.1 bits (144), Expect = 2e-09
Identities = 53/238 (22%), Positives = 112/238 (47%), Gaps = 9/238 (3%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV---EEELD 64
E ++ +QEQ + E+ ++ + + R+ E + R+ +++ EE++
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 124
R +E + +K+ E+ E E ++ +E + ++EK+ QE + +E + I E R
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL--KTVTNNLKSLEAQAEKYSQKE 182
+ +E K+ E + EE+ E K EE++ + + + Q E + Q+E
Sbjct: 426 QEQEA--KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 183 DRYE-EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+E EEI +K+ E E + E V + E+ I + E+++ +Q E+ R +++
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Score = 59.3 bits (142), Expect = 3e-09
Identities = 40/183 (21%), Positives = 84/183 (45%), Gaps = 9/183 (4%)
Query: 18 QEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKL 77
+E+ EE+ + ++ + + R+ E + +I+ EE++ +E++ +K+
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 78 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 137
E E+ E E M E + + EEKM+ QE + + + ++K E K+ E
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Query: 138 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
++ EE+ E K E EE+++ E + + Q+E +E+E+++ + K
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQ---------EQEEKMRRQEEKMWEQEVRLRQQEEK 746
Query: 198 EAE 200
E
Sbjct: 747 MQE 749
Score = 56.6 bits (135), Expect = 2e-08
Identities = 44/209 (21%), Positives = 93/209 (44%), Gaps = 15/209 (7%)
Query: 18 QEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKL 77
QE+ E+R + E K+RE E V +I+ EE+ +E++ +K+
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEK-VWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 78 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 137
E E+ + Q+ EEK+ QE +++E + + ++ + K E K+ E
Sbjct: 615 REQEE--------------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 138 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
++ EE E K E E++++ ++ E ++ +K EE++ +K++
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 198 EAETRAEFAERSVTKLEKSIDDLEDQLYQ 226
E E + E + + E + E+++ +
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 54.7 bits (130), Expect = 7e-08
Identities = 54/251 (21%), Positives = 104/251 (41%), Gaps = 19/251 (7%)
Query: 6 SLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
+L AV + + + + L EL E + A L ++QLVE E
Sbjct: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--D 123
Q + +KLE A+ + + +A+ D E+Q + K + E+ +
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQ-------QLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
R ++ K+ E ++ EE+ + E K E EE+++ ++ E + +K
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 184 RYEEEIKVLSDKLK-------EAETRAEFAERSVTKLEKSIDDLEDQLYQQ---LEQNRR 233
R EE + +K++ E E + E + + E+ I +LE+++++Q EQ +
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 234 LTNELKLALNE 244
E K+ E
Sbjct: 413 RQEEEKIREQE 423
Score = 51.2 bits (121), Expect = 8e-07
Identities = 39/171 (22%), Positives = 79/171 (46%), Gaps = 4/171 (2%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E V R+ ++EQ + +E+ + ++ E K+RE E + +I+ EE++ +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQ---EEKIREQEEK-IQEQEEKIREQEEKIREQE 639
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
E +K+ E E+ E E M+ E + EEK+ QE +++E + + + +
Sbjct: 640 EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Query: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY 178
E K+ E + EE+ + E K EE++ L+ E + +++
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 48.5 bits (114), Expect = 5e-06
Identities = 55/241 (22%), Positives = 110/241 (45%), Gaps = 19/241 (7%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
E ++ K LQE+ E +Q L+ + R+ A + +++Q + L +
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQ--LNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
Query: 68 ERLATALQ-KLEEAE---KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
+ ++ LQ ++EE E + + E M E + Q+ EEK++ QE +++E E+
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ----EEKI 330
Query: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
R+ EE R+ E + EE+ E E EE+++ + E + + +
Sbjct: 331 REQEEKMRRQ---EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 184 RYEEEIKVLSDKLKEAETRAEFAER-----SVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
EE+I+ L +K+ E E E E+ + + EK + E ++++Q E+ R ++
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKI 446
Query: 239 K 239
+
Sbjct: 447 R 447
Score = 37.0 bits (84), Expect = 0.016
Identities = 44/247 (17%), Positives = 100/247 (40%), Gaps = 44/247 (17%)
Query: 16 SLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQ 75
S +++ A+ + L+REL+ + L + + + + + +
Sbjct: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
Query: 76 KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVI 135
+L ++ K A E E+ + + ++ +K ADR EE+ ++
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKK---------------------ADRYIEELTKERDA 204
Query: 136 IESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSLEAQAEK---------YS 179
+ +L R E + K A+L+E+L+ V + N+K L+ + E+
Sbjct: 205 LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQ 264
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEF-------AERSVTKLEKSIDDLEDQLYQQLEQNR 232
+ D +E++ +S KL+ E E + + E+ I + E+++ +Q E+ R
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 233 RLTNELK 239
+++
Sbjct: 325 EQEEKIR 331
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 68.9 bits (167), Expect = 4e-12
Identities = 60/248 (24%), Positives = 111/248 (44%), Gaps = 15/248 (6%)
Query: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDH--ERKLRETAEADVA-----SLNRRIQLV 59
L+++ ++ LQE+ AAE Q+E D + + + +A L RI +
Sbjct: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
EEEL+ Q +L++A D+ + + S AQK+E + E Q KE K
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
Query: 120 EDAD----RKYEE----VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
++ + KY+ + K+ +E L+ + + + + E++LK V +
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQN 231
AE+Y + D+ +K L +L+EAE A+ A S KL++ ++D + +
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
Query: 232 RRLTNELK 239
L N+L+
Sbjct: 1915 SSLKNKLR 1922
Score = 65.1 bits (157), Expect = 5e-11
Identities = 74/279 (26%), Positives = 129/279 (46%), Gaps = 46/279 (16%)
Query: 6 SLEAVRRKI-RSLQEQADAAEERAGTLQR-------ELDHERKLRETA-------EADVA 50
+L+A++ + R LQ + + +EE+ L R EL+ ERK R A E D+
Sbjct: 1561 NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK 1620
Query: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEI 107
L I + D A ++L ++++ + D++ + I ++A+++E+K ME
Sbjct: 1621 DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEA 1680
Query: 108 QEIQLKEAKHIAEDADRKYEEVARKLV--IIESDLERA---EERAELSEGKCAELEEEL- 161
+ IQL+E AE A R+ ++ +L I S + A EE+ L E + A+LEEEL
Sbjct: 1681 EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRL-EARIAQLEEELE 1739
Query: 162 ------KTVTNNLKSLEAQ--------------AEKYSQKEDRYEEEIKVLSDKLKEAE- 200
+ + + LK Q A+K + E + K L KL+E E
Sbjct: 1740 EEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEG 1799
Query: 201 TRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
T + S+T LE I LE+QL + ++ + +++
Sbjct: 1800 TVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
Score = 60.1 bits (144), Expect = 2e-09
Identities = 62/227 (27%), Positives = 108/227 (47%), Gaps = 29/227 (12%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
+KIR L+ Q LQ +L+ ER R AE L ++ ++ EL+ + +
Sbjct: 1104 KKIRELESQISE-------LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD--S 1154
Query: 72 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 131
TA Q+ E K E K +E A+ E +IQE++ K ++ + E A++ E+ R
Sbjct: 1155 TAAQQ-ELRSKREQEVNILKKTLEEEAKTHEA--QIQEMRQKHSQAVEELAEQ-LEQTKR 1210
Query: 132 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 191
++++LE+A++ E G EL E+K + E K + E +++
Sbjct: 1211 ----VKANLEKAKQTLENERG---ELANEVKVLLQGKGDSE-------HKRKKVEAQLQE 1256
Query: 192 LSDKLKEAE-TRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNE 237
L K E E R E A++ VTKL+ +D++ L Q ++ +LT +
Sbjct: 1257 LQVKFNEGERVRTELADK-VTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Score = 58.9 bits (141), Expect = 4e-09
Identities = 60/263 (22%), Positives = 113/263 (42%), Gaps = 35/263 (13%)
Query: 17 LQEQADA-------AEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQER 69
LQEQ A AEE L + ++ EA V R Q ++ E + Q+
Sbjct: 885 LQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN 944
Query: 70 LATALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKY 126
+ ++LEE E A + + E++ +K EE+ +E Q +L + K + ED ++
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 127 -------EEVARKL-----------VIIESDLERAEERAELSEGKCAELEEELKTVTNNL 168
EE ++ L +E L R E++ + E +LE + +++ +
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 169 KSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQL 228
L+AQ + + + EEE++ +++E + A + + +LE I +L++ L +
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 229 -------EQNRRLTNELKLALNE 244
+Q R L EL+ E
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTE 1147
Score = 58.5 bits (140), Expect = 5e-09
Identities = 55/240 (22%), Positives = 113/240 (47%), Gaps = 19/240 (7%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHER-KLRETAEADVA------SLNRRIQLVEEELDR 65
K+R Q A+ TLQ +L E+ +L+E +A+ L R+ ++EL+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 125
L ++EE E+ + K ++ Q+ EE++E +E ++ + + K
Sbjct: 916 ICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK 972
Query: 126 YEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRY 185
+++ + +I+E + + +L E + AE T NL E +++ ++ ++++
Sbjct: 973 LKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-------TTNLTEEEEKSKSLAKLKNKH 1025
Query: 186 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
E I L ++L+ E + + E++ KLE DL DQ+ + Q L +++LA E+
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL--KMQLAKKEE 1083
Score = 58.2 bits (139), Expect = 7e-09
Identities = 50/225 (22%), Positives = 100/225 (44%), Gaps = 9/225 (4%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ LE + QE E+ L++ L+ E K T EA + + ++ EEL
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAK---THEAQIQEMRQKHSQAVEELA 1202
Query: 65 RAQERLATALQKLEEAEKAADESERG-----MKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
E+ LE+A++ E+ERG +KV+ E K + E QL+E +
Sbjct: 1203 EQLEQTKRVKANLEKAKQTL-ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF 1261
Query: 120 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
+ +R E+A K+ ++ +L+ S+ K ++L ++ + + L+ + ++ +
Sbjct: 1262 NEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
+++ ++K + D+ + E E + LEK I L Q+
Sbjct: 1322 RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Score = 55.5 bits (132), Expect = 4e-08
Identities = 56/259 (21%), Positives = 121/259 (46%), Gaps = 25/259 (9%)
Query: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
M + LE + ++ R+ E ++++ G EL+ K + E V + +++ +E
Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE---KSKRALEQQVEEMKTQLEELE 1545
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME--IQEIQLKEAKHI 118
+EL +A E L+ +A KA E + ++ R ++ EEK + +++++ EA+
Sbjct: 1546 DEL-QATEDAKLRLEVNLQAMKAQFERD-----LQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 119 AEDADRKYEEVARK-----LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 173
E R ARK L +E+ ++ A + + + + +L+ ++K L A
Sbjct: 1600 DERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQ------ 227
E+ + E+++K + ++ + + AER+ + ++ D+L D++
Sbjct: 1660 SREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGAL 1719
Query: 228 -LEQNRRLTNELKLALNED 245
LE+ RRL E ++A E+
Sbjct: 1720 ALEEKRRL--EARIAQLEE 1736
Score = 55.1 bits (131), Expect = 6e-08
Identities = 49/211 (23%), Positives = 97/211 (45%), Gaps = 21/211 (9%)
Query: 40 KLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 99
KL+ EA + L R++ E++ ++ L +KLE D ++ ++ E +AQ
Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQ----RQELEKTRRKLE-----GDSTDLSDQIAELQAQ 1070
Query: 100 KDEEKMEI----QEIQLKEAKHIAEDADR-----KYEEVARKLVIIESDLERAEERAELS 150
E KM++ +E+Q A+ E A + K E+ ++ ++ DLE +
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 151 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 210
E + +L EEL+ + L+ + + E+E+ +L L+E A+ E +
Sbjct: 1131 EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE---EAKTHEAQI 1187
Query: 211 TKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
++ + ++L +QLEQ +R+ L+ A
Sbjct: 1188 QEMRQKHSQAVEELAEQLEQTKRVKANLEKA 1218
Score = 53.1 bits (126), Expect = 2e-07
Identities = 50/249 (20%), Positives = 122/249 (48%), Gaps = 25/249 (10%)
Query: 6 SLEAVRRKIRSLQEQADAAEERAGTLQREL----DHERKLRETAEADVASLNRRIQLVEE 61
S+ + + R+L++Q + + + L+ EL D + +L +A A R +Q +E
Sbjct: 1519 SVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE 1578
Query: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
+ + +++L ++++E AE + +R M V A + + +M++++++ HI +
Sbjct: 1579 QSEEKKKQLVRQVREME-AELEDERKQRSMAV----AARKKLEMDLKDLEA----HI-DS 1628
Query: 122 ADRKYEEVARKLVIIESDLE---------RAEERAELSEGKCAELEEELKTVTNNLKSLE 172
A++ +E ++L +++ ++ RA L++ K E E++LK++ + L+
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK--ENEKKLKSMEAEMIQLQ 1686
Query: 173 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNR 232
+ + + + ++E L+D++ + + A +LE I LE++L ++
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 233 RLTNELKLA 241
+ + LK A
Sbjct: 1747 LINDRLKKA 1755
Score = 52.0 bits (123), Expect = 5e-07
Identities = 54/225 (24%), Positives = 101/225 (44%), Gaps = 27/225 (12%)
Query: 25 EERAGTLQRELDHERKLRETAEADVASLNRRI-----QLVE--EELDRAQERLATALQKL 77
EER +++ K R E D L+ +I Q+ E +L + +E L AL ++
Sbjct: 1033 EERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARV 1092
Query: 78 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 137
EE + + + ++ +ES+ + +E +E + +A+ D + E + +L E
Sbjct: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL---E 1149
Query: 138 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
L+ + EL + E+ KT+ K+ EAQ ++ QK + EE L+++L+
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE---LAEQLE 1206
Query: 198 EAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLAL 242
+ +R LEK+ LE+ + L NE+K+ L
Sbjct: 1207 Q-------TKRVKANLEKAKQTLEN-------ERGELANEVKVLL 1237
Score = 49.7 bits (117), Expect = 2e-06
Identities = 54/242 (22%), Positives = 112/242 (46%), Gaps = 17/242 (7%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
++LE ++ + + E+ + A E LQ + D E K R+ EA + L Q+ E +
Sbjct: 1213 ANLEKAKQTLEN--ERGELANEVKVLLQGKGDSEHK-RKKVEAQLQEL----QVKFNEGE 1265
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 124
R + LA + KL+ D + +S++ K + E QL++ + + ++ +R
Sbjct: 1266 RVRTELADKVTKLQVE---LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENR 1322
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT----VTNNLKSLEAQA---EK 177
+ ++ KL +E + E+ E E LE+++ T V + K +E E
Sbjct: 1323 QKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLET 1382
Query: 178 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNE 237
+ + + +++++ LS + +E + E++ T+L++ +DDL L Q + L +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 238 LK 239
K
Sbjct: 1443 QK 1444
Score = 48.9 bits (115), Expect = 4e-06
Identities = 50/248 (20%), Positives = 108/248 (43%), Gaps = 24/248 (9%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRR-------I 56
S+ L+ V + S +EQ + EE L++++ T A VA + ++ +
Sbjct: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQI-------ATLHAQVADMKKKMEDSVGCL 1380
Query: 57 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 116
+ EE + Q+ L Q+ EE A D+ E+ ++R Q++ + + + +++
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK----TKTRLQQELDDLLVDLDHQRQSA 1436
Query: 117 HIAEDADRKYEEVARKLVIIES----DLERAEERAELSEGKCAELEEELKTVTNNLKSLE 172
E +K++++ + I + + +RAE A E K L L+ LE
Sbjct: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
Query: 173 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNR 232
+++ + + + + E E E+ V +++ +++LED+L Q ++
Sbjct: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL--QATEDA 1554
Query: 233 RLTNELKL 240
+L E+ L
Sbjct: 1555 KLRLEVNL 1562
Score = 47.0 bits (110), Expect = 2e-05
Identities = 53/255 (20%), Positives = 109/255 (42%), Gaps = 34/255 (13%)
Query: 6 SLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
+LE ++K L + + + + E + +ET +A + EL+R
Sbjct: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 1497
Query: 66 AQERLATALQKL----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
++ T ++ L ++ K+ E E+ + +E + E+M+ Q +L++ ED
Sbjct: 1498 LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV----EEMKTQLEELEDELQATED 1553
Query: 122 ADRKYE-EVARKLVIIESDLERAEERAELSEGKC--------AELEEE----------LK 162
A + E + E DL+ +E++E + + AELE+E K
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK 1613
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA-----ETRAEFAE--RSVTKLEK 215
+ +LK LEA + ++ D ++++ L ++K+ +TRA E + EK
Sbjct: 1614 KLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK 1673
Query: 216 SIDDLEDQLYQQLEQ 230
+ +E ++ Q E+
Sbjct: 1674 KLKSMEAEMIQLQEE 1688
Score = 45.4 bits (106), Expect = 4e-05
Identities = 42/209 (20%), Positives = 87/209 (41%), Gaps = 11/209 (5%)
Query: 3 GSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLN------RRI 56
G+ +LE RR + + + EE G + D +K + LN ++
Sbjct: 1717 GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 57 QLVEEELDRAQERLATALQKLEEAEKA---ADESERGMKVIESRAQKDEEKMEIQEI--Q 111
+ ++L+R + L LQ++E K+ A + K+ + Q D E E Q Q
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQ 1836
Query: 112 LKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
++ + +D + ++ R + ++A R + + + E EEE + + + L
Sbjct: 1837 VRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1896
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAE 200
+ + E ++ D E+ L +KL+ +
Sbjct: 1897 QRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 45.1 bits (105), Expect = 6e-05
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
Query: 5 SSLEAVRRKIRSLQEQAD-AAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
+S+ A+ KI L+EQ D +ER ++ E+KL++ V R + +++
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL-LQVDDERRNAEQYKDQA 1865
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
D+A RL ++LEEAE+ A + + ++ + E + ++ K+ D
Sbjct: 1866 DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Query: 124 RKY---EEVARKLVIIESDLERAEERAELSEGKCAE 156
+ +ARK SD E + +A+ +E K AE
Sbjct: 1926 LPFVVPRRMARKGAGDGSD-EEVDGKADGAEAKPAE 1960
Score = 30.8 bits (68), Expect = 1.1
Identities = 21/100 (21%), Positives = 45/100 (45%)
Query: 140 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 199
+ R EE E + ++ E+ N L +E + ++ + +E+++ ++ EA
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 200 ETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
E +LE+ DLE ++ ++ E+ + L E K
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK 939
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 68.9 bits (167), Expect = 4e-12
Identities = 67/271 (24%), Positives = 123/271 (45%), Gaps = 49/271 (18%)
Query: 15 RSLQEQADAAEERAGTLQR-------ELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
R LQ + + EE+ LQR EL+ ERK R A A L ++ +E + D A
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDE------------EKMEIQEIQLKE- 114
+ A+++L + + + +R ++ ++RA +DE + +E +QL+E
Sbjct: 1638 KGREEAIKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 115 ---AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
A+ + AD + EE+A +L S ++ E + A+LEEEL+ N++++
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 172 EAQAEKYSQKEDRYEEEI---------------------KVLSDKLKEAE--TRAEFAER 208
+ K +Q+ ++ E+ K L KL E E +++F +
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KS 1814
Query: 209 SVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
++ LE I LE+Q+ Q+ + + T LK
Sbjct: 1815 TIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/228 (21%), Positives = 108/228 (47%), Gaps = 12/228 (5%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKL----RETAEADVASLNRRIQLV 59
+ SLEA +++ A+ A ++A + EL E R + + L RI +
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAK 116
EEEL+ Q + ++ +A + A++ + S AQK+E +++E Q +L+
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 117 HIAEDADR-KYEE----VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
H E A + K++ + K+ +E +E+ + + + +++LK + ++
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
AE+Y ++ ++ +K L +L+EAE ++ + KL++ +D+
Sbjct: 1862 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Score = 61.2 bits (147), Expect = 8e-10
Identities = 56/233 (24%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 20 QADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 79
Q EE + EL ++ ++ AE ++ L ++ + EE + QE+L + E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 80 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
AE+ E E + +E+R +++E++ Q++Q A+RK ++A++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRG--QQLQ----------AERK--KMAQQ 951
Query: 133 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 192
++ +E LE E + + + E ++K + + + ++ Q K S++ EE I L
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 193 SDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
+ L E E +A+ + K E I +LE +L ++ E++R+ +LK L D
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE-EKSRQELEKLKRKLEGD 1063
Score = 61.2 bits (147), Expect = 8e-10
Identities = 54/243 (22%), Positives = 111/243 (45%), Gaps = 26/243 (10%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+ +++ L+++ E LQ +L E +L AE L + Q +EE L +
Sbjct: 869 QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEME 928
Query: 68 ERLATALQKLEEAEK-----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
RL EE E A+ + ++++ Q +EE+ Q++QL++ A
Sbjct: 929 ARL-------EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV-----TA 976
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
+ K +++ ++++++ + + +L LEE + +T NL E +A+ ++ +
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKL-------LEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLAL 242
+++E I L +LK+ E + E+ KLE D +Q+ Q L +++LA
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL--KMQLAK 1087
Query: 243 NED 245
E+
Sbjct: 1088 KEE 1090
Score = 57.0 bits (136), Expect = 1e-08
Identities = 45/214 (21%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 1 MAGSSSLEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAE------ADVASLN 53
++G ++L+ +R++ + + + + EE G ++ D RK + AE A S
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
++ + ++L+R + L + L ++E A K+ +S + +E++ + EE++E + + +
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1838
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE----------GKCAELEEELKT 163
A + D+K +E+ L+ +E + + AE+ E +E + E EEE +
Sbjct: 1839 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
+ N + L+ + ++ ++ + E+ L KL+
Sbjct: 1896 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 14/231 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ LE + QE E+ L++ LD E + + EA V + ++ EEL
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETR---SHEAQVQEMRQKHAQAVEELT 1209
Query: 65 RAQERLATALQKLEEAEKAADESERGM----KVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
E+ A L++ ++ ++ + +V+ Q+ E K + E Q++E +
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA------- 173
D +R E+ K+ +++++E +EGK +L +++ ++++ L+ +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
Q S K + EEE L D+L E + ER ++ L + D + +L
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Score = 55.1 bits (131), Expect = 6e-08
Identities = 56/244 (22%), Positives = 110/244 (45%), Gaps = 35/244 (14%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLN--------------RR 55
V K+R L EE +LQ +LD E + ++ E +++LN
Sbjct: 1334 VSTKLRQL-------EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1386
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
++ +EE R Q+ + Q+ EE A D+ E+ ++R Q++ + + + ++
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQL 1442
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
E RK++++ + I S +RAE +E + E+E K + SL
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAE-AEAR----EKETKAL-----SLARAL 1492
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLT 235
E+ + ++ E K+L ++++ + + ++V +LEKS LE Q+ + Q L
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 236 NELK 239
+EL+
Sbjct: 1553 DELQ 1556
Score = 51.6 bits (122), Expect = 6e-07
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 44/271 (16%)
Query: 8 EAVRRKIRSLQEQA--------DAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV 59
E +++R LQ Q DA R ++E+K + + EAD+ L +
Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK-SLEADLMQLQEDLAAA 1699
Query: 60 EE-------ELDRAQERLATALQ--------------KLEEAEKAADESERGMKVIESRA 98
E E + E LA++L ++ + E+ +E + M+ + R
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 99 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS-------- 150
+K ++ E +L + A+ + +++ R+ + S L E +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819
Query: 151 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS- 209
E K A+LEE+ V + +A + QK+ + +E + + D+ K AE E AE+
Sbjct: 1820 EAKIAQLEEQ---VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 210 --VTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
V +L++ +++ E++ + R+L EL
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 51.2 bits (121), Expect = 8e-07
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 51/276 (18%)
Query: 11 RRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA---- 66
++K++ +A EE Q+E+++ + E A L + +++ELD
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDL 1436
Query: 67 --QERLATALQKLEE------------AEKAADESERGMKVIESRAQKDEEKMEIQEIQL 112
Q +L + L+K + + K ADE +R E+ A++ E K L
Sbjct: 1437 DNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARAL 1492
Query: 113 KEAKHIAEDADR--------------KYEEVARKLVIIESDLERAEERAELSEGKCAELE 158
+EA E+ +R ++V + + +E E + E + + ELE
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 159 EELKTVTN-------NLKSLEAQAEKYSQ-KEDRYEEEIKVLSDKLKEAETRAE------ 204
+EL+ + N+++L+ Q E+ Q ++++ EE+ + L +L E ET E
Sbjct: 1553 DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 205 -FAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
A + KLE + DLE Q ++ +L+
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Score = 49.7 bits (117), Expect = 2e-06
Identities = 65/280 (23%), Positives = 131/280 (46%), Gaps = 48/280 (17%)
Query: 7 LEAVRRKIRS----LQEQADAAEERAGTLQRE-LDHERKLRETAEADVA------SLNRR 55
L+A R+K+ L+EQ + E LQ E + E K+++ + + L++
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE-KMEIQEIQLKE 114
+L+EE + LA +K + K ++ E + +E R +K+E+ + E+++++ K
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK- 1059
Query: 115 AKHIAEDADRKYEEVAR-KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL-- 171
+ DA +E++A + I E ++ A++ EL + A L++E+ N LK +
Sbjct: 1060 ---LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAALARLDDEIAQKNNALKKIRE 1115
Query: 172 --------------EAQAEKYSQKEDR-YEEEIKVLSDKLKEA--------ETRAEFAER 208
E A ++K+ R EE++ L +L++ E RA+ E+
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQ 1174
Query: 209 SVTKLEKSIDD----LEDQLYQQLEQNRRLTNELKLALNE 244
VT L+K++D+ E Q+ + +++ + EL L +
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
Score = 48.9 bits (115), Expect = 4e-06
Identities = 58/251 (23%), Positives = 111/251 (44%), Gaps = 42/251 (16%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEE--------LD 64
KI+ L+++ +++ +L ERKL E +D+ + L EEE L
Sbjct: 979 KIKKLEDEILVMDDQ----NNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLK 1029
Query: 65 RAQERLATALQ-KLEEAEKAADESERGMKVIESRAQKDEEKM-----EIQEIQLKEAKHI 118
E + + L+ +L++ EK+ E E+ + +E A E++ +I E++++ AK
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 119 AE----------------DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 162
E +A +K E+ + ++ DL+ +E + +L EEL+
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 222
+ L+ + + E+E+ VL L E ETR+ E V ++ + +
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH--EAQVQEMRQKHAQAVE 1206
Query: 223 QLYQQLEQNRR 233
+L +QLEQ +R
Sbjct: 1207 ELTEQLEQFKR 1217
Score = 48.5 bits (114), Expect = 5e-06
Identities = 53/246 (21%), Positives = 105/246 (42%), Gaps = 16/246 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
S+LE +RK L + + + + E + +ET +A +EEL+
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 65 RAQERLATALQKL----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
R + L ++ L ++ K E E+ + +E+ Q +E K +++E L++ E
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET--QMEEMKTQLEE--LEDELQATE 1559
Query: 121 DADRKYEEVARKLVIIESDLER-AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
DA + E + ++ ER + R E +E K +L+ +L L+ Q +
Sbjct: 1560 DAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1616
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+ + E ++K L + A E A + + KL+ + D + ++LE R +E+
Sbjct: 1617 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDARASRDEIF 1672
Query: 240 LALNED 245
E+
Sbjct: 1673 ATAKEN 1678
Score = 47.8 bits (112), Expect = 9e-06
Identities = 44/225 (19%), Positives = 101/225 (44%), Gaps = 10/225 (4%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEAD----VASLNRRIQLV 59
+ +L ++ K S+ + + ++ ++EL+ ++ E +D +A L +I +
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
+ +L + +E L AL +L++ + + + ++ +E +E ++ + +A+
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 120 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
D + E + +L E L+ + EL + E+ K + +S EAQ ++
Sbjct: 1142 RDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
QK + EE+ ++ K A+ +++ LEK DL +L
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKAN---LDKNKQTLEKENADLAGEL 1240
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/243 (20%), Positives = 110/243 (45%), Gaps = 12/243 (4%)
Query: 7 LEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
LE +R + + ++E EE LQ D + +L +A R +Q +E+ +
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKD-EEKMEIQEIQLKEAKHIAEDADR 124
+ +L L + E E ER + + + A+K E ++ E+Q A E+A +
Sbjct: 1590 KRRQLQRQLHEYETEL----EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE---AQAEKYSQK 181
+ ++ ++ + +LE A + E E++ K++ +L L+ A AE+ ++
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 182 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
D +EE L+++L + + + +LE I LE++L ++ +++ ++ A
Sbjct: 1706 ADLEKEE---LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 242 LNE 244
+
Sbjct: 1763 TQQ 1765
Score = 39.3 bits (90), Expect = 0.003
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 22/145 (15%)
Query: 5 SSLEAVRRKIRSLQEQAD--AAEERAGT------------LQRELDHERKL----RETAE 46
S++ A+ KI L+EQ + A E++A T + +++ ERK+ +E AE
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
Query: 47 ---ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 103
A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Query: 104 KMEIQEIQLKEAKHIAEDADRKYEE 128
+ + + + E+AD EE
Sbjct: 1934 TSFVPS-RRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 68.9 bits (167), Expect = 4e-12
Identities = 67/271 (24%), Positives = 123/271 (45%), Gaps = 49/271 (18%)
Query: 15 RSLQEQADAAEERAGTLQR-------ELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
R LQ + + EE+ LQR EL+ ERK R A A L ++ +E + D A
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDE------------EKMEIQEIQLKE- 114
+ A+++L + + + +R ++ ++RA +DE + +E +QL+E
Sbjct: 1645 KGREEAIKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 115 ---AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
A+ + AD + EE+A +L S ++ E + A+LEEEL+ N++++
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 172 EAQAEKYSQKEDRYEEEI---------------------KVLSDKLKEAE--TRAEFAER 208
+ K +Q+ ++ E+ K L KL E E +++F +
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KS 1821
Query: 209 SVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
++ LE I LE+Q+ Q+ + + T LK
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/228 (21%), Positives = 108/228 (47%), Gaps = 12/228 (5%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKL----RETAEADVASLNRRIQLV 59
+ SLEA +++ A+ A ++A + EL E R + + L RI +
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAK 116
EEEL+ Q + ++ +A + A++ + S AQK+E +++E Q +L+
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 117 HIAEDADR-KYEE----VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
H E A + K++ + K+ +E +E+ + + + +++LK + ++
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
AE+Y ++ ++ +K L +L+EAE ++ + KL++ +D+
Sbjct: 1869 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Score = 61.2 bits (147), Expect = 8e-10
Identities = 56/233 (24%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 20 QADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 79
Q EE + EL ++ ++ AE ++ L ++ + EE + QE+L + E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 80 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
AE+ E E + +E+R +++E++ Q++Q A+RK ++A++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRG--QQLQ----------AERK--KMAQQ 958
Query: 133 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 192
++ +E LE E + + + E ++K + + + ++ Q K S++ EE I L
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 193 SDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
+ L E E +A+ + K E I +LE +L ++ E++R+ +LK L D
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE-EKSRQELEKLKRKLEGD 1070
Score = 61.2 bits (147), Expect = 8e-10
Identities = 54/243 (22%), Positives = 111/243 (45%), Gaps = 26/243 (10%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+ +++ L+++ E LQ +L E +L AE L + Q +EE L +
Sbjct: 876 QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEME 935
Query: 68 ERLATALQKLEEAEK-----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
RL EE E A+ + ++++ Q +EE+ Q++QL++ A
Sbjct: 936 ARL-------EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV-----TA 983
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
+ K +++ ++++++ + + +L LEE + +T NL E +A+ ++ +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKL-------LEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLAL 242
+++E I L +LK+ E + E+ KLE D +Q+ Q L +++LA
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL--KMQLAK 1094
Query: 243 NED 245
E+
Sbjct: 1095 KEE 1097
Score = 57.0 bits (136), Expect = 1e-08
Identities = 45/214 (21%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 1 MAGSSSLEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAE------ADVASLN 53
++G ++L+ +R++ + + + + EE G ++ D RK + AE A S
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
++ + ++L+R + L + L ++E A K+ +S + +E++ + EE++E + + +
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1845
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE----------GKCAELEEELKT 163
A + D+K +E+ L+ +E + + AE+ E +E + E EEE +
Sbjct: 1846 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
+ N + L+ + ++ ++ + E+ L KL+
Sbjct: 1903 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 14/231 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ LE + QE E+ L++ LD E + + EA V + ++ EEL
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETR---SHEAQVQEMRQKHAQAVEELT 1216
Query: 65 RAQERLATALQKLEEAEKAADESERGM----KVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
E+ A L++ ++ ++ + +V+ Q+ E K + E Q++E +
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA------- 173
D +R E+ K+ +++++E +EGK +L +++ ++++ L+ +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
Q S K + EEE L D+L E + ER ++ L + D + +L
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Score = 55.1 bits (131), Expect = 6e-08
Identities = 56/244 (22%), Positives = 110/244 (45%), Gaps = 35/244 (14%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLN--------------RR 55
V K+R L EE +LQ +LD E + ++ E +++LN
Sbjct: 1341 VSTKLRQL-------EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1393
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
++ +EE R Q+ + Q+ EE A D+ E+ ++R Q++ + + + ++
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQL 1449
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
E RK++++ + I S +RAE +E + E+E K + SL
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAE-AEAR----EKETKAL-----SLARAL 1499
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLT 235
E+ + ++ E K+L ++++ + + ++V +LEKS LE Q+ + Q L
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 236 NELK 239
+EL+
Sbjct: 1560 DELQ 1563
Score = 51.6 bits (122), Expect = 6e-07
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 44/271 (16%)
Query: 8 EAVRRKIRSLQEQA--------DAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV 59
E +++R LQ Q DA R ++E+K + + EAD+ L +
Sbjct: 1648 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK-SLEADLMQLQEDLAAA 1706
Query: 60 EE-------ELDRAQERLATALQ--------------KLEEAEKAADESERGMKVIESRA 98
E E + E LA++L ++ + E+ +E + M+ + R
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 99 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS-------- 150
+K ++ E +L + A+ + +++ R+ + S L E +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826
Query: 151 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS- 209
E K A+LEE+ V + +A + QK+ + +E + + D+ K AE E AE+
Sbjct: 1827 EAKIAQLEEQ---VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 210 --VTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
V +L++ +++ E++ + R+L EL
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 51.2 bits (121), Expect = 8e-07
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 51/276 (18%)
Query: 11 RRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA---- 66
++K++ +A EE Q+E+++ + E A L + +++ELD
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDL 1443
Query: 67 --QERLATALQKLEE------------AEKAADESERGMKVIESRAQKDEEKMEIQEIQL 112
Q +L + L+K + + K ADE +R E+ A++ E K L
Sbjct: 1444 DNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARAL 1499
Query: 113 KEAKHIAEDADR--------------KYEEVARKLVIIESDLERAEERAELSEGKCAELE 158
+EA E+ +R ++V + + +E E + E + + ELE
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 159 EELKTVTN-------NLKSLEAQAEKYSQ-KEDRYEEEIKVLSDKLKEAETRAE------ 204
+EL+ + N+++L+ Q E+ Q ++++ EE+ + L +L E ET E
Sbjct: 1560 DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 205 -FAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
A + KLE + DLE Q ++ +L+
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Score = 49.7 bits (117), Expect = 2e-06
Identities = 65/280 (23%), Positives = 131/280 (46%), Gaps = 48/280 (17%)
Query: 7 LEAVRRKIRS----LQEQADAAEERAGTLQRE-LDHERKLRETAEADVA------SLNRR 55
L+A R+K+ L+EQ + E LQ E + E K+++ + + L++
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE-KMEIQEIQLKE 114
+L+EE + LA +K + K ++ E + +E R +K+E+ + E+++++ K
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK- 1066
Query: 115 AKHIAEDADRKYEEVAR-KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL-- 171
+ DA +E++A + I E ++ A++ EL + A L++E+ N LK +
Sbjct: 1067 ---LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAALARLDDEIAQKNNALKKIRE 1122
Query: 172 --------------EAQAEKYSQKEDR-YEEEIKVLSDKLKEA--------ETRAEFAER 208
E A ++K+ R EE++ L +L++ E RA+ E+
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQ 1181
Query: 209 SVTKLEKSIDD----LEDQLYQQLEQNRRLTNELKLALNE 244
VT L+K++D+ E Q+ + +++ + EL L +
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221
Score = 48.9 bits (115), Expect = 4e-06
Identities = 58/251 (23%), Positives = 111/251 (44%), Gaps = 42/251 (16%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEE--------LD 64
KI+ L+++ +++ +L ERKL E +D+ + L EEE L
Sbjct: 986 KIKKLEDEILVMDDQ----NNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLK 1036
Query: 65 RAQERLATALQ-KLEEAEKAADESERGMKVIESRAQKDEEKM-----EIQEIQLKEAKHI 118
E + + L+ +L++ EK+ E E+ + +E A E++ +I E++++ AK
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 119 AE----------------DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 162
E +A +K E+ + ++ DL+ +E + +L EEL+
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 222
+ L+ + + E+E+ VL L E ETR+ E V ++ + +
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH--EAQVQEMRQKHAQAVE 1213
Query: 223 QLYQQLEQNRR 233
+L +QLEQ +R
Sbjct: 1214 ELTEQLEQFKR 1224
Score = 48.5 bits (114), Expect = 5e-06
Identities = 53/246 (21%), Positives = 105/246 (42%), Gaps = 16/246 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
S+LE +RK L + + + + E + +ET +A +EEL+
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 65 RAQERLATALQKL----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
R + L ++ L ++ K E E+ + +E+ Q +E K +++E L++ E
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET--QMEEMKTQLEE--LEDELQATE 1566
Query: 121 DADRKYEEVARKLVIIESDLER-AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
DA + E + ++ ER + R E +E K +L+ +L L+ Q +
Sbjct: 1567 DAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1623
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+ + E ++K L + A E A + + KL+ + D + ++LE R +E+
Sbjct: 1624 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDARASRDEIF 1679
Query: 240 LALNED 245
E+
Sbjct: 1680 ATAKEN 1685
Score = 47.8 bits (112), Expect = 9e-06
Identities = 44/225 (19%), Positives = 101/225 (44%), Gaps = 10/225 (4%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEAD----VASLNRRIQLV 59
+ +L ++ K S+ + + ++ ++EL+ ++ E +D +A L +I +
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
+ +L + +E L AL +L++ + + + ++ +E +E ++ + +A+
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 120 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
D + E + +L E L+ + EL + E+ K + +S EAQ ++
Sbjct: 1149 RDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
QK + EE+ ++ K A+ +++ LEK DL +L
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKAN---LDKNKQTLEKENADLAGEL 1247
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/243 (20%), Positives = 110/243 (45%), Gaps = 12/243 (4%)
Query: 7 LEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
LE +R + + ++E EE LQ D + +L +A R +Q +E+ +
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKD-EEKMEIQEIQLKEAKHIAEDADR 124
+ +L L + E E ER + + + A+K E ++ E+Q A E+A +
Sbjct: 1597 KRRQLQRQLHEYETEL----EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE---AQAEKYSQK 181
+ ++ ++ + +LE A + E E++ K++ +L L+ A AE+ ++
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 182 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
D +EE L+++L + + + +LE I LE++L ++ +++ ++ A
Sbjct: 1713 ADLEKEE---LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 242 LNE 244
+
Sbjct: 1770 TQQ 1772
Score = 39.3 bits (90), Expect = 0.003
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 22/145 (15%)
Query: 5 SSLEAVRRKIRSLQEQAD--AAEERAGT------------LQRELDHERKL----RETAE 46
S++ A+ KI L+EQ + A E++A T + +++ ERK+ +E AE
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880
Query: 47 ---ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 103
A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Query: 104 KMEIQEIQLKEAKHIAEDADRKYEE 128
+ + + + E+AD EE
Sbjct: 1941 TSFVPS-RRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 68.9 bits (167), Expect = 4e-12
Identities = 67/271 (24%), Positives = 123/271 (45%), Gaps = 49/271 (18%)
Query: 15 RSLQEQADAAEERAGTLQR-------ELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
R LQ + + EE+ LQR EL+ ERK R A A L ++ +E + D A
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDE------------EKMEIQEIQLKE- 114
+ A+++L + + + +R ++ ++RA +DE + +E +QL+E
Sbjct: 1645 KGREEAIKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 115 ---AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
A+ + AD + EE+A +L S ++ E + A+LEEEL+ N++++
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 172 EAQAEKYSQKEDRYEEEI---------------------KVLSDKLKEAE--TRAEFAER 208
+ K +Q+ ++ E+ K L KL E E +++F +
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KS 1821
Query: 209 SVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
++ LE I LE+Q+ Q+ + + T LK
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/228 (21%), Positives = 108/228 (47%), Gaps = 12/228 (5%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKL----RETAEADVASLNRRIQLV 59
+ SLEA +++ A+ A ++A + EL E R + + L RI +
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAK 116
EEEL+ Q + ++ +A + A++ + S AQK+E +++E Q +L+
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808
Query: 117 HIAEDADR-KYEE----VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
H E A + K++ + K+ +E +E+ + + + +++LK + ++
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
AE+Y ++ ++ +K L +L+EAE ++ + KL++ +D+
Sbjct: 1869 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Score = 61.2 bits (147), Expect = 8e-10
Identities = 56/233 (24%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 20 QADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 79
Q EE + EL ++ ++ AE ++ L ++ + EE + QE+L + E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 80 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
AE+ E E + +E+R +++E++ Q++Q A+RK ++A++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRG--QQLQ----------AERK--KMAQQ 958
Query: 133 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 192
++ +E LE E + + + E ++K + + + ++ Q K S++ EE I L
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 193 SDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
+ L E E +A+ + K E I +LE +L ++ E++R+ +LK L D
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE-EKSRQELEKLKRKLEGD 1070
Score = 61.2 bits (147), Expect = 8e-10
Identities = 54/243 (22%), Positives = 111/243 (45%), Gaps = 26/243 (10%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+ +++ L+++ E LQ +L E +L AE L + Q +EE L +
Sbjct: 876 QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEME 935
Query: 68 ERLATALQKLEEAEK-----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
RL EE E A+ + ++++ Q +EE+ Q++QL++ A
Sbjct: 936 ARL-------EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV-----TA 983
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
+ K +++ ++++++ + + +L LEE + +T NL E +A+ ++ +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKL-------LEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLAL 242
+++E I L +LK+ E + E+ KLE D +Q+ Q L +++LA
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL--KMQLAK 1094
Query: 243 NED 245
E+
Sbjct: 1095 KEE 1097
Score = 57.0 bits (136), Expect = 1e-08
Identities = 45/214 (21%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 1 MAGSSSLEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAE------ADVASLN 53
++G ++L+ +R++ + + + + EE G ++ D RK + AE A S
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
++ + ++L+R + L + L ++E A K+ +S + +E++ + EE++E + + +
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1845
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE----------GKCAELEEELKT 163
A + D+K +E+ L+ +E + + AE+ E +E + E EEE +
Sbjct: 1846 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
+ N + L+ + ++ ++ + E+ L KL+
Sbjct: 1903 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 14/231 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ LE + QE E+ L++ LD E + + EA V + ++ EEL
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETR---SHEAQVQEMRQKHAQAVEELT 1216
Query: 65 RAQERLATALQKLEEAEKAADESERGM----KVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
E+ A L++ ++ ++ + +V+ Q+ E K + E Q++E +
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA------- 173
D +R E+ K+ +++++E +EGK +L +++ ++++ L+ +
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1336
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
Q S K + EEE L D+L E + ER ++ L + D + +L
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Score = 55.1 bits (131), Expect = 6e-08
Identities = 56/244 (22%), Positives = 110/244 (45%), Gaps = 35/244 (14%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLN--------------RR 55
V K+R L EE +LQ +LD E + ++ E +++LN
Sbjct: 1341 VSTKLRQL-------EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1393
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
++ +EE R Q+ + Q+ EE A D+ E+ ++R Q++ + + + ++
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQL 1449
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
E RK++++ + I S +RAE +E + E+E K + SL
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAE-AEAR----EKETKAL-----SLARAL 1499
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLT 235
E+ + ++ E K+L ++++ + + ++V +LEKS LE Q+ + Q L
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 236 NELK 239
+EL+
Sbjct: 1560 DELQ 1563
Score = 51.6 bits (122), Expect = 6e-07
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 44/271 (16%)
Query: 8 EAVRRKIRSLQEQA--------DAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV 59
E +++R LQ Q DA R ++E+K + + EAD+ L +
Sbjct: 1648 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK-SLEADLMQLQEDLAAA 1706
Query: 60 EE-------ELDRAQERLATALQ--------------KLEEAEKAADESERGMKVIESRA 98
E E + E LA++L ++ + E+ +E + M+ + R
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 99 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS-------- 150
+K ++ E +L + A+ + +++ R+ + S L E +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826
Query: 151 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS- 209
E K A+LEE+ V + +A + QK+ + +E + + D+ K AE E AE+
Sbjct: 1827 EAKIAQLEEQ---VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 210 --VTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
V +L++ +++ E++ + R+L EL
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 51.2 bits (121), Expect = 8e-07
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 51/276 (18%)
Query: 11 RRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA---- 66
++K++ +A EE Q+E+++ + E A L + +++ELD
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDL 1443
Query: 67 --QERLATALQKLEE------------AEKAADESERGMKVIESRAQKDEEKMEIQEIQL 112
Q +L + L+K + + K ADE +R E+ A++ E K L
Sbjct: 1444 DNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARAL 1499
Query: 113 KEAKHIAEDADR--------------KYEEVARKLVIIESDLERAEERAELSEGKCAELE 158
+EA E+ +R ++V + + +E E + E + + ELE
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 159 EELKTVTN-------NLKSLEAQAEKYSQ-KEDRYEEEIKVLSDKLKEAETRAE------ 204
+EL+ + N+++L+ Q E+ Q ++++ EE+ + L +L E ET E
Sbjct: 1560 DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 205 -FAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
A + KLE + DLE Q ++ +L+
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Score = 49.7 bits (117), Expect = 2e-06
Identities = 65/280 (23%), Positives = 131/280 (46%), Gaps = 48/280 (17%)
Query: 7 LEAVRRKIRS----LQEQADAAEERAGTLQRE-LDHERKLRETAEADVA------SLNRR 55
L+A R+K+ L+EQ + E LQ E + E K+++ + + L++
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE-KMEIQEIQLKE 114
+L+EE + LA +K + K ++ E + +E R +K+E+ + E+++++ K
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK- 1066
Query: 115 AKHIAEDADRKYEEVAR-KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL-- 171
+ DA +E++A + I E ++ A++ EL + A L++E+ N LK +
Sbjct: 1067 ---LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAALARLDDEIAQKNNALKKIRE 1122
Query: 172 --------------EAQAEKYSQKEDR-YEEEIKVLSDKLKEA--------ETRAEFAER 208
E A ++K+ R EE++ L +L++ E RA+ E+
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQ 1181
Query: 209 SVTKLEKSIDD----LEDQLYQQLEQNRRLTNELKLALNE 244
VT L+K++D+ E Q+ + +++ + EL L +
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221
Score = 48.9 bits (115), Expect = 4e-06
Identities = 58/251 (23%), Positives = 111/251 (44%), Gaps = 42/251 (16%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEE--------LD 64
KI+ L+++ +++ +L ERKL E +D+ + L EEE L
Sbjct: 986 KIKKLEDEILVMDDQ----NNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLK 1036
Query: 65 RAQERLATALQ-KLEEAEKAADESERGMKVIESRAQKDEEKM-----EIQEIQLKEAKHI 118
E + + L+ +L++ EK+ E E+ + +E A E++ +I E++++ AK
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 119 AE----------------DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 162
E +A +K E+ + ++ DL+ +E + +L EEL+
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 222
+ L+ + + E+E+ VL L E ETR+ E V ++ + +
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH--EAQVQEMRQKHAQAVE 1213
Query: 223 QLYQQLEQNRR 233
+L +QLEQ +R
Sbjct: 1214 ELTEQLEQFKR 1224
Score = 48.5 bits (114), Expect = 5e-06
Identities = 53/246 (21%), Positives = 105/246 (42%), Gaps = 16/246 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
S+LE +RK L + + + + E + +ET +A +EEL+
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 65 RAQERLATALQKL----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
R + L ++ L ++ K E E+ + +E+ Q +E K +++E L++ E
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET--QMEEMKTQLEE--LEDELQATE 1566
Query: 121 DADRKYEEVARKLVIIESDLER-AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
DA + E + ++ ER + R E +E K +L+ +L L+ Q +
Sbjct: 1567 DAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1623
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+ + E ++K L + A E A + + KL+ + D + ++LE R +E+
Sbjct: 1624 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDARASRDEIF 1679
Query: 240 LALNED 245
E+
Sbjct: 1680 ATAKEN 1685
Score = 47.8 bits (112), Expect = 9e-06
Identities = 44/225 (19%), Positives = 101/225 (44%), Gaps = 10/225 (4%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEAD----VASLNRRIQLV 59
+ +L ++ K S+ + + ++ ++EL+ ++ E +D +A L +I +
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
+ +L + +E L AL +L++ + + + ++ +E +E ++ + +A+
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 120 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
D + E + +L E L+ + EL + E+ K + +S EAQ ++
Sbjct: 1149 RDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
QK + EE+ ++ K A+ +++ LEK DL +L
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKAN---LDKNKQTLEKENADLAGEL 1247
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/243 (20%), Positives = 110/243 (45%), Gaps = 12/243 (4%)
Query: 7 LEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
LE +R + + ++E EE LQ D + +L +A R +Q +E+ +
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKD-EEKMEIQEIQLKEAKHIAEDADR 124
+ +L L + E E ER + + + A+K E ++ E+Q A E+A +
Sbjct: 1597 KRRQLQRQLHEYETEL----EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE---AQAEKYSQK 181
+ ++ ++ + +LE A + E E++ K++ +L L+ A AE+ ++
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 182 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
D +EE L+++L + + + +LE I LE++L ++ +++ ++ A
Sbjct: 1713 ADLEKEE---LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 242 LNE 244
+
Sbjct: 1770 TQQ 1772
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 68.9 bits (167), Expect = 4e-12
Identities = 67/271 (24%), Positives = 123/271 (45%), Gaps = 49/271 (18%)
Query: 15 RSLQEQADAAEERAGTLQR-------ELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
R LQ + + EE+ LQR EL+ ERK R A A L ++ +E + D A
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDE------------EKMEIQEIQLKE- 114
+ A+++L + + + +R ++ ++RA +DE + +E +QL+E
Sbjct: 1638 KGREEAIKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 115 ---AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
A+ + AD + EE+A +L S ++ E + A+LEEEL+ N++++
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 172 EAQAEKYSQKEDRYEEEI---------------------KVLSDKLKEAE--TRAEFAER 208
+ K +Q+ ++ E+ K L KL E E +++F +
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF-KS 1814
Query: 209 SVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
++ LE I LE+Q+ Q+ + + T LK
Sbjct: 1815 TIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/228 (21%), Positives = 108/228 (47%), Gaps = 12/228 (5%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKL----RETAEADVASLNRRIQLV 59
+ SLEA +++ A+ A ++A + EL E R + + L RI +
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAK 116
EEEL+ Q + ++ +A + A++ + S AQK+E +++E Q +L+
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801
Query: 117 HIAEDADR-KYEE----VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 171
H E A + K++ + K+ +E +E+ + + + +++LK + ++
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Query: 172 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
AE+Y ++ ++ +K L +L+EAE ++ + KL++ +D+
Sbjct: 1862 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Score = 61.2 bits (147), Expect = 8e-10
Identities = 56/233 (24%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 20 QADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 79
Q EE + EL ++ ++ AE ++ L ++ + EE + QE+L + E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 80 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 132
AE+ E E + +E+R +++E++ Q++Q A+RK ++A++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRG--QQLQ----------AERK--KMAQQ 951
Query: 133 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 192
++ +E LE E + + + E ++K + + + ++ Q K S++ EE I L
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 193 SDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED 245
+ L E E +A+ + K E I +LE +L ++ E++R+ +LK L D
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE-EKSRQELEKLKRKLEGD 1063
Score = 61.2 bits (147), Expect = 8e-10
Identities = 54/243 (22%), Positives = 111/243 (45%), Gaps = 26/243 (10%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
+ +++ L+++ E LQ +L E +L AE L + Q +EE L +
Sbjct: 869 QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEME 928
Query: 68 ERLATALQKLEEAEK-----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
RL EE E A+ + ++++ Q +EE+ Q++QL++ A
Sbjct: 929 ARL-------EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV-----TA 976
Query: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
+ K +++ ++++++ + + +L LEE + +T NL E +A+ ++ +
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKL-------LEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLAL 242
+++E I L +LK+ E + E+ KLE D +Q+ Q L +++LA
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL--KMQLAK 1087
Query: 243 NED 245
E+
Sbjct: 1088 KEE 1090
Score = 57.0 bits (136), Expect = 1e-08
Identities = 45/214 (21%), Positives = 105/214 (49%), Gaps = 22/214 (10%)
Query: 1 MAGSSSLEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAE------ADVASLN 53
++G ++L+ +R++ + + + + EE G ++ D RK + AE A S
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113
++ + ++L+R + L + L ++E A K+ +S + +E++ + EE++E + + +
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQ 1838
Query: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE----------GKCAELEEELKT 163
A + D+K +E+ L+ +E + + AE+ E +E + E EEE +
Sbjct: 1839 AATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
+ N + L+ + ++ ++ + E+ L KL+
Sbjct: 1896 INANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 14/231 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ LE + QE E+ L++ LD E + + EA V + ++ EEL
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETR---SHEAQVQEMRQKHAQAVEELT 1209
Query: 65 RAQERLATALQKLEEAEKAADESERGM----KVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
E+ A L++ ++ ++ + +V+ Q+ E K + E Q++E +
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA------- 173
D +R E+ K+ +++++E +EGK +L +++ ++++ L+ +
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETR 1329
Query: 174 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
Q S K + EEE L D+L E + ER ++ L + D + +L
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Score = 55.1 bits (131), Expect = 6e-08
Identities = 56/244 (22%), Positives = 110/244 (45%), Gaps = 35/244 (14%)
Query: 10 VRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLN--------------RR 55
V K+R L EE +LQ +LD E + ++ E +++LN
Sbjct: 1334 VSTKLRQL-------EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1386
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
++ +EE R Q+ + Q+ EE A D+ E+ ++R Q++ + + + ++
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQELDDLVVDLDNQRQL 1442
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
E RK++++ + I S +RAE +E + E+E K + SL
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAE-AEAR----EKETKAL-----SLARAL 1492
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLT 235
E+ + ++ E K+L ++++ + + ++V +LEKS LE Q+ + Q L
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 236 NELK 239
+EL+
Sbjct: 1553 DELQ 1556
Score = 51.6 bits (122), Expect = 6e-07
Identities = 57/271 (21%), Positives = 113/271 (41%), Gaps = 44/271 (16%)
Query: 8 EAVRRKIRSLQEQA--------DAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLV 59
E +++R LQ Q DA R ++E+K + + EAD+ L +
Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK-SLEADLMQLQEDLAAA 1699
Query: 60 EE-------ELDRAQERLATALQ--------------KLEEAEKAADESERGMKVIESRA 98
E E + E LA++L ++ + E+ +E + M+ + R
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 99 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS-------- 150
+K ++ E +L + A+ + +++ R+ + S L E +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819
Query: 151 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS- 209
E K A+LEE+ V + +A + QK+ + +E + + D+ K AE E AE+
Sbjct: 1820 EAKIAQLEEQ---VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 210 --VTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
V +L++ +++ E++ + R+L EL
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 51.2 bits (121), Expect = 8e-07
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 51/276 (18%)
Query: 11 RRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA---- 66
++K++ +A EE Q+E+++ + E A L + +++ELD
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDL 1436
Query: 67 --QERLATALQKLEE------------AEKAADESERGMKVIESRAQKDEEKMEIQEIQL 112
Q +L + L+K + + K ADE +R E+ A++ E K L
Sbjct: 1437 DNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARAL 1492
Query: 113 KEAKHIAEDADR--------------KYEEVARKLVIIESDLERAEERAELSEGKCAELE 158
+EA E+ +R ++V + + +E E + E + + ELE
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 159 EELKTVTN-------NLKSLEAQAEKYSQ-KEDRYEEEIKVLSDKLKEAETRAE------ 204
+EL+ + N+++L+ Q E+ Q ++++ EE+ + L +L E ET E
Sbjct: 1553 DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 205 -FAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
A + KLE + DLE Q ++ +L+
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Score = 49.7 bits (117), Expect = 2e-06
Identities = 65/280 (23%), Positives = 131/280 (46%), Gaps = 48/280 (17%)
Query: 7 LEAVRRKIRS----LQEQADAAEERAGTLQRE-LDHERKLRETAEADVA------SLNRR 55
L+A R+K+ L+EQ + E LQ E + E K+++ + + L++
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE-KMEIQEIQLKE 114
+L+EE + LA +K + K ++ E + +E R +K+E+ + E+++++ K
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK- 1059
Query: 115 AKHIAEDADRKYEEVAR-KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL-- 171
+ DA +E++A + I E ++ A++ EL + A L++E+ N LK +
Sbjct: 1060 ---LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAALARLDDEIAQKNNALKKIRE 1115
Query: 172 --------------EAQAEKYSQKEDR-YEEEIKVLSDKLKEA--------ETRAEFAER 208
E A ++K+ R EE++ L +L++ E RA+ E+
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK-REQ 1174
Query: 209 SVTKLEKSIDD----LEDQLYQQLEQNRRLTNELKLALNE 244
VT L+K++D+ E Q+ + +++ + EL L +
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
Score = 48.9 bits (115), Expect = 4e-06
Identities = 58/251 (23%), Positives = 111/251 (44%), Gaps = 42/251 (16%)
Query: 13 KIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEE--------LD 64
KI+ L+++ +++ +L ERKL E +D+ + L EEE L
Sbjct: 979 KIKKLEDEILVMDDQ----NNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLK 1029
Query: 65 RAQERLATALQ-KLEEAEKAADESERGMKVIESRAQKDEEKM-----EIQEIQLKEAKHI 118
E + + L+ +L++ EK+ E E+ + +E A E++ +I E++++ AK
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 119 AE----------------DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 162
E +A +K E+ + ++ DL+ +E + +L EEL+
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 163 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 222
+ L+ + + E+E+ VL L E ETR+ E V ++ + +
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE-ETRSH--EAQVQEMRQKHAQAVE 1206
Query: 223 QLYQQLEQNRR 233
+L +QLEQ +R
Sbjct: 1207 ELTEQLEQFKR 1217
Score = 48.5 bits (114), Expect = 5e-06
Identities = 53/246 (21%), Positives = 105/246 (42%), Gaps = 16/246 (6%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
S+LE +RK L + + + + E + +ET +A +EEL+
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 65 RAQERLATALQKL----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
R + L ++ L ++ K E E+ + +E+ Q +E K +++E L++ E
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET--QMEEMKTQLEE--LEDELQATE 1559
Query: 121 DADRKYEEVARKLVIIESDLER-AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
DA + E + ++ ER + R E +E K +L+ +L L+ Q +
Sbjct: 1560 DAKLRLEV---NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1616
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELK 239
+ + E ++K L + A E A + + KL+ + D + ++LE R +E+
Sbjct: 1617 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDARASRDEIF 1672
Query: 240 LALNED 245
E+
Sbjct: 1673 ATAKEN 1678
Score = 47.8 bits (112), Expect = 9e-06
Identities = 44/225 (19%), Positives = 101/225 (44%), Gaps = 10/225 (4%)
Query: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEAD----VASLNRRIQLV 59
+ +L ++ K S+ + + ++ ++EL+ ++ E +D +A L +I +
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Query: 60 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 119
+ +L + +E L AL +L++ + + + ++ +E +E ++ + +A+
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 120 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 179
D + E + +L E L+ + EL + E+ K + +S EAQ ++
Sbjct: 1142 RDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQL 224
QK + EE+ ++ K A+ +++ LEK DL +L
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKAN---LDKNKQTLEKENADLAGEL 1240
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/243 (20%), Positives = 110/243 (45%), Gaps = 12/243 (4%)
Query: 7 LEAVRRKIRS-LQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDR 65
LE +R + + ++E EE LQ D + +L +A R +Q +E+ +
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIESRAQKD-EEKMEIQEIQLKEAKHIAEDADR 124
+ +L L + E E ER + + + A+K E ++ E+Q A E+A +
Sbjct: 1590 KRRQLQRQLHEYETEL----EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 125 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE---AQAEKYSQK 181
+ ++ ++ + +LE A + E E++ K++ +L L+ A AE+ ++
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 182 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
D +EE L+++L + + + +LE I LE++L ++ +++ ++ A
Sbjct: 1706 ADLEKEE---LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 242 LNE 244
+
Sbjct: 1763 TQQ 1765
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 68.9 bits (167), Expect = 4e-12
Identities = 59/248 (23%), Positives = 124/248 (50%), Gaps = 29/248 (11%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
++++ +Q++ E L+ EL L+ TAE L ++ ++ EE D Q +L
Sbjct: 679 QELKDVQDELRIKENELRALEEEL---AGLKNTAEK-YRQLKQQWEMKTEEADLLQTKLQ 734
Query: 72 TAL-----QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
+ ++L+ +K +ESE +K + +K EEK E+ E ++K A +A+R+
Sbjct: 735 QSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNA-----EAERE- 788
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR-- 184
R+L + L+ A+ +A+ S K E ++E++ +T L+ L+ + Y Q+ +
Sbjct: 789 ----RELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVN 844
Query: 185 -----YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI---DDLEDQLYQQLEQNRRLTN 236
YE +I+V++ ++ + + A+ VTK ++ I D + Y ++ +++ N
Sbjct: 845 EAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNN 904
Query: 237 ELKLALNE 244
+ +L + E
Sbjct: 905 DSQLKIKE 912
Score = 51.2 bits (121), Expect = 8e-07
Identities = 54/239 (22%), Positives = 102/239 (42%), Gaps = 27/239 (11%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ L+ K R L++Q + E A LQ +L ++ E D +L + I+ EE L
Sbjct: 703 AGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELD--ALKKTIEESEETLK 760
Query: 65 RAQERLATALQKLEEAEK----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
+E A +K E E A E ER +K + + + K + ++KE + E
Sbjct: 761 NTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVE 820
Query: 121 DADRKYEEVARKLVIIESDLERAEE------------RAELSEGKCA------ELEEELK 162
+ EE+ R+ + LE E AE+++ K + E+ ++ +
Sbjct: 821 AITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKE 880
Query: 163 TVTNN---LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 218
+T +K+ A+ K+ ++ + + +IK L + + + AE V+K+ K D
Sbjct: 881 VITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYD 939
Score = 39.3 bits (90), Expect = 0.003
Identities = 39/209 (18%), Positives = 85/209 (40%), Gaps = 26/209 (12%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKL------------RETAEADVASLNRR 55
E + I+ L+E+ + E + RE++H +L + + ++ + +
Sbjct: 201 EEITPTIQKLKEERSSYLEYQKVM-REIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDK 259
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
+ ++EEL +++ ++EE EK D+ G+ + E L EA
Sbjct: 260 VIKLQEELSENDKKIKALNHEIEELEKRKDKETGGI-------------LRSLEDALAEA 306
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
+ + + ++ + L ES + E+ A E+E+K +T+ L +L+ +
Sbjct: 307 QRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLHALQEAS 366
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAE 204
K ++ ++ +S L E AE
Sbjct: 367 NKDAEALAAAQQHFNAVSAGLSSNEDGAE 395
Score = 37.7 bits (86), Expect = 0.009
Identities = 42/179 (23%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDH-ERKLRETAEADVASLNRRIQLVE 60
A ++ + + +LQE ++ E Q+ + L + A+L ++ +
Sbjct: 347 AKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACK 406
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
++ +AQ A KL+ A++ + +K ++S +KD+E +E + +LKE K AE
Sbjct: 407 NDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVK-RLKE-KLEAE 464
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSE--GKCAELEEELKTVTNNLKSLEAQAEK 177
YEE + ++ E+R +LS G+ E E L NL+ EK
Sbjct: 465 MKKLNYEENKEESLL--------EKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEK 515
Score = 28.1 bits (61), Expect = 7.3
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 18/137 (13%)
Query: 86 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 145
E G ++ E + ++ +E +E +LKE K I E EE+ + ++ EE
Sbjct: 166 EEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILE------EEITPTIQKLK------EE 213
Query: 146 RAELSEGKCAELE-EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 204
R+ E + E E L + + L A+ K R EE+K + DK+ + +
Sbjct: 214 RSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKV-----RSAEELKEMQDKVIKLQEELS 268
Query: 205 FAERSVTKLEKSIDDLE 221
++ + L I++LE
Sbjct: 269 ENDKKIKALNHEIEELE 285
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 68.9 bits (167), Expect = 4e-12
Identities = 59/248 (23%), Positives = 124/248 (50%), Gaps = 29/248 (11%)
Query: 12 RKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLA 71
++++ +Q++ E L+ EL L+ TAE L ++ ++ EE D Q +L
Sbjct: 679 QELKDVQDELRIKENELRALEEEL---AGLKNTAEK-YRQLKQQWEMKTEEADLLQTKLQ 734
Query: 72 TAL-----QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
+ ++L+ +K +ESE +K + +K EEK E+ E ++K A +A+R+
Sbjct: 735 QSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNA-----EAERE- 788
Query: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR-- 184
R+L + L+ A+ +A+ S K E ++E++ +T L+ L+ + Y Q+ +
Sbjct: 789 ----RELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVN 844
Query: 185 -----YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI---DDLEDQLYQQLEQNRRLTN 236
YE +I+V++ ++ + + A+ VTK ++ I D + Y ++ +++ N
Sbjct: 845 EAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNN 904
Query: 237 ELKLALNE 244
+ +L + E
Sbjct: 905 DSQLKIKE 912
Score = 51.2 bits (121), Expect = 8e-07
Identities = 54/239 (22%), Positives = 102/239 (42%), Gaps = 27/239 (11%)
Query: 5 SSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELD 64
+ L+ K R L++Q + E A LQ +L ++ E D +L + I+ EE L
Sbjct: 703 AGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELD--ALKKTIEESEETLK 760
Query: 65 RAQERLATALQKLEEAEK----AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
+E A +K E E A E ER +K + + + K + ++KE + E
Sbjct: 761 NTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVE 820
Query: 121 DADRKYEEVARKLVIIESDLERAEE------------RAELSEGKCA------ELEEELK 162
+ EE+ R+ + LE E AE+++ K + E+ ++ +
Sbjct: 821 AITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKE 880
Query: 163 TVTNN---LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 218
+T +K+ A+ K+ ++ + + +IK L + + + AE V+K+ K D
Sbjct: 881 VITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYD 939
Score = 39.3 bits (90), Expect = 0.003
Identities = 39/209 (18%), Positives = 85/209 (40%), Gaps = 26/209 (12%)
Query: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKL------------RETAEADVASLNRR 55
E + I+ L+E+ + E + RE++H +L + + ++ + +
Sbjct: 201 EEITPTIQKLKEERSSYLEYQKVM-REIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDK 259
Query: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
+ ++EEL +++ ++EE EK D+ G+ + E L EA
Sbjct: 260 VIKLQEELSENDKKIKALNHEIEELEKRKDKETGGI-------------LRSLEDALAEA 306
Query: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
+ + + ++ + L ES + E+ A E+E+K +T+ L +L+ +
Sbjct: 307 QRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLHALQEAS 366
Query: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAE 204
K ++ ++ +S L E AE
Sbjct: 367 NKDAEALAAAQQHFNAVSAGLSSNEDGAE 395
Score = 37.7 bits (86), Expect = 0.009
Identities = 42/179 (23%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDH-ERKLRETAEADVASLNRRIQLVE 60
A ++ + + +LQE ++ E Q+ + L + A+L ++ +
Sbjct: 347 AKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACK 406
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
++ +AQ A KL+ A++ + +K ++S +KD+E +E + +LKE K AE
Sbjct: 407 NDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVK-RLKE-KLEAE 464
Query: 121 DADRKYEEVARKLVIIESDLERAEERAELSE--GKCAELEEELKTVTNNLKSLEAQAEK 177
YEE + ++ E+R +LS G+ E E L NL+ EK
Sbjct: 465 MKKLNYEENKEESLL--------EKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEK 515
Score = 28.1 bits (61), Expect = 7.3
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 18/137 (13%)
Query: 86 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 145
E G ++ E + ++ +E +E +LKE K I E EE+ + ++ EE
Sbjct: 166 EEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILE------EEITPTIQKLK------EE 213
Query: 146 RAELSEGKCAELE-EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 204
R+ E + E E L + + L A+ K R EE+K + DK+ + +
Sbjct: 214 RSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKV-----RSAEELKEMQDKVIKLQEELS 268
Query: 205 FAERSVTKLEKSIDDLE 221
++ + L I++LE
Sbjct: 269 ENDKKIKALNHEIEELE 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.122 0.295
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,141,493
Number of Sequences: 37866
Number of extensions: 321876
Number of successful extensions: 12141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 724
Number of HSP's successfully gapped in prelim test: 884
Number of HSP's that attempted gapping in prelim test: 2680
Number of HSP's gapped (non-prelim): 5471
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.