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Search of human proteins with 63252900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 531 e-151
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 502 e-142
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 486 e-138
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 479 e-135
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 456 e-128
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 455 e-128
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 450 e-127
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 443 e-125
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 421 e-118
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 412 e-115
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 330 7e-91
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 322 2e-88
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 317 6e-87
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 316 1e-86
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 310 7e-85
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 296 1e-80
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 283 2e-76
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 84 1e-16
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 84 1e-16
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 83 3e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 81 1e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 3e-15
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 5e-15
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 79 5e-15
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 79 6e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 6e-15
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 79 6e-15
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 79 6e-15
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 77 2e-14
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 77 2e-14
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 531 bits (1367), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 502 bits (1292), Expect = e-142
Identities = 268/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 486 bits (1251), Expect = e-138
Identities = 262/284 (92%), Positives = 272/284 (95%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 479 bits (1232), Expect = e-135
Identities = 257/284 (90%), Positives = 268/284 (94%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 456 bits (1172), Expect = e-128
Identities = 245/284 (86%), Positives = 263/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 455 bits (1171), Expect = e-128
Identities = 235/284 (82%), Positives = 266/284 (93%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 450 bits (1157), Expect = e-127
Identities = 241/284 (84%), Positives = 259/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 443 bits (1139), Expect = e-125
Identities = 232/282 (82%), Positives = 259/282 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 421 bits (1083), Expect = e-118
Identities = 222/284 (78%), Positives = 255/284 (89%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 412 bits (1060), Expect = e-115
Identities = 216/284 (76%), Positives = 252/284 (88%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + LEE+L+I+ LK+L A DKYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE++V K + ++ + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 330 bits (847), Expect = 7e-91
Identities = 172/240 (71%), Positives = 205/240 (85%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/114 (26%), Positives = 60/114 (52%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ + +++ + ++ L L + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 322 bits (825), Expect = 2e-88
Identities = 168/242 (69%), Positives = 205/242 (84%)
Query: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
KYEEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+
Sbjct: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL E
Sbjct: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
Query: 281 LN 282
LN
Sbjct: 245 LN 246
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/114 (31%), Positives = 63/114 (55%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +L+ + E A +RAE +E E+ K + + L SL+ + ++ DKY
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/174 (21%), Positives = 81/174 (46%), Gaps = 29/174 (16%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE---DEL 57
+D ++++ E A A+++E K E+R+ + E+++ + +LK + +E
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 58 D-KYSEA----------LKDAQEKLELAEKKATDAEADVASLNRRIQLVE---------- 96
D KY E L+ A+E+ E++E K D E ++ ++ ++ +E
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
Query: 97 ----EELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQE 145
EE+ ++L A + E AE+ + E+ + +E + AQ EE + + +
Sbjct: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQ 236
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 317 bits (813), Expect = 6e-87
Identities = 173/238 (72%), Positives = 196/238 (82%)
Query: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/179 (21%), Positives = 80/179 (44%), Gaps = 28/179 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGT----EDE 56
+D ++++ E A A+++E K E R+++ E+++ + +LK ED
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
Query: 57 LDKYSEA----------LKDAQEKLELAEKKATDAEADVASLNRRIQLVE---------- 96
KY E L+ A+E+ EL+E K + E ++ ++ ++ +E
Sbjct: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
Query: 97 ----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 151
EE+ ++L A + E AE++ + E+ + +E + + E+ +LK A
Sbjct: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 316 bits (810), Expect = 1e-86
Identities = 167/240 (69%), Positives = 200/240 (83%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 55.1 bits (131), Expect = 7e-08
Identities = 33/114 (28%), Positives = 61/114 (53%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ E+ K + + L SL+ + + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 310 bits (795), Expect = 7e-85
Identities = 164/237 (69%), Positives = 196/237 (82%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 41.6 bits (96), Expect = 8e-04
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESRC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++ E++ L ++ A +++ EEE+ ++L A + E AE++ + E
Sbjct: 155 REMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+ + +E R E+ + +LK H
Sbjct: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 296 bits (758), Expect = 1e-80
Identities = 159/237 (67%), Positives = 191/237 (80%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESKC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ +E+L+ EA +++ EEE+ ++L A + E AE++ + E
Sbjct: 155 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+ + +E R E+ + +LK H
Sbjct: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 283 bits (723), Expect = 2e-76
Identities = 150/230 (65%), Positives = 186/230 (80%), Gaps = 7/230 (3%)
Query: 62 EALKDAQEKLELAEKKATD----AEADVASLNRRIQLVEEELDRAQERLATA---LQKLE 114
+A+K + L+L ++ A D AEAD R + +EEE Q++L ++K
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E
Sbjct: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
+LER+EERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKE
Sbjct: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 181
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
AETRAEFAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 182 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
Score = 102 bits (253), Expect = 5e-22
Identities = 75/219 (34%), Positives = 108/219 (49%), Gaps = 74/219 (33%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD-- 58
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 59 -----------------------------------------------KYSEA-------- 63
KY E
Sbjct: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
Query: 64 --LKDAQEKLELAEKKATDAEADVASLNRRIQLV--------------EEELDRAQERLA 107
L+ ++E+ E+AE +A E ++ ++++ ++ + EEE+ +E+L
Sbjct: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
Query: 108 TALQKLEEAEKAADESERGMKVI-ESRAQKDEEKMEIQE 145
A + E AE++ + E+ + + E+ A EE +EI +
Sbjct: 181 EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 219
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 14/121 (11%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKG---TEDEL- 57
+ + +K+ +L+ + E + +RAE AE R++QLE+EL ++ + LK +E+E
Sbjct: 110 EEVARKLVILEGELERSEERAE-------VAESRARQLEEELRTMDQALKSLMASEEEYS 162
Query: 58 ---DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
DKY E +K +EKL+ AE +A AE VA L + I +EE L A+E Q L+
Sbjct: 163 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLD 222
Query: 115 E 115
+
Sbjct: 223 Q 223
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 84.3 bits (207), Expect = 1e-16
Identities = 59/250 (23%), Positives = 127/250 (50%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEEL-----------DRAQERLATALQKLEEAEKAADESERGMKVIES 132
+ + +IQ EEE+ ++ QE++ +K+ E ++ E E M E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ 192
+ ++ EE M+ QE +L+E + ++ + K +E K I+ E+ +E+ E + Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK---IQRQEEKIQEQEEKTWRQEKL 491
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLE 250
L+++ +I +Q K E + Q+E E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEEKV 260
+ +LEE++
Sbjct: 552 VRLQELEERL 561
Score = 82.0 bits (201), Expect = 5e-16
Identities = 63/276 (22%), Positives = 138/276 (50%), Gaps = 11/276 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+++ K ++Q+ D + L+RA Q ++ + + +L EL S+ KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E ++ E + ++ EEKM QE +++E E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E+ E ++R+ +E++R ++ + E+K + E+ +++ +KL+E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQ----EEKLREVEEKMQ 458
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + + E+ I EEK+ +E+ ++L Q
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 73.9 bits (180), Expect = 1e-13
Identities = 70/301 (23%), Positives = 132/301 (43%), Gaps = 41/301 (13%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-------DK 59
K L+L + A R E + ++ D + ++ + L K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEE 215
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLE 114
E + QEKL L E + ++ + +V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 115 EAEKAADES-----------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
+A E E M E + Q+ EEKM QE++++E + + K
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 164 EVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLKALMAAEDKYSQKE 218
E K+ E + R EE+ E ++R+ EE++ +I +Q K E+ + Q+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 219 D-------------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
R E++++ +K++E E E + +LE+ + D EEK+ +E
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 266 E 266
+
Sbjct: 456 K 456
Score = 73.2 bits (178), Expect = 2e-13
Identities = 51/224 (22%), Positives = 115/224 (51%), Gaps = 4/224 (1%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + ++ +E ++ + E + +++ ++ E+E+ ++K++ E+ + E L+
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ +EK++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGQVRQL-EEQLRIMDQTLKALMAAEDKYS--QKEDRYEEEIK 226
G R+ ++L + L+ + +++ S Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/235 (23%), Positives = 120/235 (51%), Gaps = 16/235 (6%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ K+ E + EE+ +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQE 521
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E ++++ EE++R +Q ++ L E+K ++E R +E L ++L + +AE
Sbjct: 522 QEEKMQRQEEKMR--EQEVR-LWQQEEKMQEQEVRLQE----LEERLGKLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 84.3 bits (207), Expect = 1e-16
Identities = 59/250 (23%), Positives = 127/250 (50%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEEL-----------DRAQERLATALQKLEEAEKAADESERGMKVIES 132
+ + +IQ EEE+ ++ QE++ +K+ E ++ E E M E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ 192
+ ++ EE M+ QE +L+E + ++ + K +E K I+ E+ +E+ E + Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK---IQRQEEKIQEQEEKTWRQEKL 491
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLE 250
L+++ +I +Q K E + Q+E E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEEKV 260
+ +LEE++
Sbjct: 552 VRLQELEERL 561
Score = 82.0 bits (201), Expect = 5e-16
Identities = 63/276 (22%), Positives = 138/276 (50%), Gaps = 11/276 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+++ K ++Q+ D + L+RA Q ++ + + +L EL S+ KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E ++ E + ++ EEKM QE +++E E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E+ E ++R+ +E++R ++ + E+K + E+ +++ +KL+E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQ----EEKLREVEEKMQ 458
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + + E+ I EEK+ +E+ ++L Q
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 73.9 bits (180), Expect = 1e-13
Identities = 70/301 (23%), Positives = 132/301 (43%), Gaps = 41/301 (13%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-------DK 59
K L+L + A R E + ++ D + ++ + L K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEE 215
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLE 114
E + QEKL L E + ++ + +V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 115 EAEKAADES-----------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
+A E E M E + Q+ EEKM QE++++E + + K
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 164 EVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLKALMAAEDKYSQKE 218
E K+ E + R EE+ E ++R+ EE++ +I +Q K E+ + Q+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 219 D-------------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
R E++++ +K++E E E + +LE+ + D EEK+ +E
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 266 E 266
+
Sbjct: 456 K 456
Score = 73.2 bits (178), Expect = 2e-13
Identities = 51/224 (22%), Positives = 115/224 (51%), Gaps = 4/224 (1%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + ++ +E ++ + E + +++ ++ E+E+ ++K++ E+ + E L+
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ +EK++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGQVRQL-EEQLRIMDQTLKALMAAEDKYS--QKEDRYEEEIK 226
G R+ ++L + L+ + +++ S Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 67.4 bits (163), Expect = 1e-11
Identities = 55/235 (23%), Positives = 120/235 (51%), Gaps = 16/235 (6%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ K+ E + EE+ +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQE 521
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E ++++ EE++R +Q ++ L E+K ++E R +E L ++L + +AE
Sbjct: 522 QEEKMQRQEEKMR--EQEVR-LWQQEEKMQEQEVRLQE----LEERLGKLGQKAE 569
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 82.8 bits (203), Expect = 3e-16
Identities = 55/255 (21%), Positives = 131/255 (51%), Gaps = 6/255 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++LE+++ Q+K++ E++ + E ++
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHE-QEKIREQEEKRQE-EEKIR 373
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ QEK + E K E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 374 E-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E+ ++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E ++R+ E+++R ++ ++ + +K EE++ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VTKLEKSIDDLEEKV 260
+ + E + EEK+
Sbjct: 553 MREQEVRLRQQEEKM 567
Score = 81.6 bits (200), Expect = 7e-16
Identities = 55/252 (21%), Positives = 122/252 (48%), Gaps = 21/252 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K + R EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK--------------MRRQEE 495
Query: 182 RAELSEGQVRQLEEQLR----IMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKE 234
+ E ++R+ EE++R +M + + + E+K ++E++ EE+++ +K++E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 235 AETRAEFAERSV 246
E R E +
Sbjct: 556 QEVRLRQQEEKM 567
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/283 (18%), Positives = 136/283 (48%), Gaps = 10/283 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEDELVSLQKKLKGTEDELDK 59
+ ++ K+Q ++++ +R Q + +K E++ ++ E+++ ++K++ E+++ +
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + +EK+ E+ + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADES------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 173
++ E ++ E + ++ EE M+ QE ++ E + + + + +E K+ E
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+ E++ E ++R+ EE ++ ++ + + K EE+++ +K++
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 234 EAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E E + E + + E+ + + EEK+ +E+ + + +
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 75.9 bits (185), Expect = 4e-14
Identities = 63/305 (20%), Positives = 136/305 (44%), Gaps = 49/305 (16%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 271
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDR----------- 101
+E + ++ + +EK+ E+K + E + +I+ EE++ R
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 102 ----------AQERLATALQKLEEAEKAADESERGMKVIESRAQ-----------KDEEK 140
+E++ +K+ E EK ++ E+ + + R Q + EEK
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIM 200
+ QE +++E + + ++ + K E K+ E +++ EE+ E ++R+ E+++R
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 201 DQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++ ++ + +K E ++ K++E E + E + + EK I + EEK+
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 261 AHAKE 265
+E
Sbjct: 512 REQEE 516
Score = 74.7 bits (182), Expect = 9e-14
Identities = 47/251 (18%), Positives = 125/251 (49%), Gaps = 4/251 (1%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL----ELAE 75
++ ++ E + E++ ++ E+ + ++K++ E+ + + E +++ +EK+ ++ E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
++ E + + Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 136 KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEE 195
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EG++ + E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
+++ ++ ++ + +K EE+I+ + ++E E + E + + E+ + +
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 256 LEEKVAHAKEE 266
EEK+ +E+
Sbjct: 542 QEEKMRRQEEK 552
Score = 71.2 bits (173), Expect = 9e-13
Identities = 42/201 (20%), Positives = 104/201 (51%), Gaps = 3/201 (1%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K + Q + ++E + R E+ ++ E++ ++ E+ + ++K+ E+++ + E +
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++ +EK+ E+K + E + +I+ EE + +E++ K+ E E E E
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E ++ EE+
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 185 LSEGQVRQLEEQLRIMDQTLK 205
E ++R+ E +LR ++ ++
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQ 568
Score = 70.9 bits (172), Expect = 1e-12
Identities = 63/253 (24%), Positives = 122/253 (48%), Gaps = 19/253 (7%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIES 132
++ + +V L R+++ L +++L + L LQ + +A E +
Sbjct: 225 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN- 283
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ 192
Q+ EEKM QE +++E + ++ + K E K+ E + EE+ E + +
Sbjct: 284 --QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKS 252
EE++R +++ M ++K ++E++ +EE +K++E E R E E + + E+
Sbjct: 342 KEEKIRELEEK----MHEQEKIREQEEKRQEE-----EKIREQEKRQE-QEAKMWRQEEK 391
Query: 253 IDDLEEKVAHAKE 265
I + EEK+ +E
Sbjct: 392 IREQEEKIREQEE 404
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 80.9 bits (198), Expect = 1e-15
Identities = 66/269 (24%), Positives = 132/269 (49%), Gaps = 12/269 (4%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K E + + + ++ EEE + QE + +K+ E E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE-VARKLVIIESDLERAE 180
+ E+ + E + +K EEKM QE E H E+ R+ EE V R+ I E+
Sbjct: 541 QKEK-IHEQEEKIRKQEEKMWRQE----EKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAET 237
E+ E Q +EQ M + + + E+K ++E+ R EE+I+ K++E E
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E + + E+ + + EEK+ +E+
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Score = 77.0 bits (188), Expect = 2e-14
Identities = 50/256 (19%), Positives = 127/256 (49%), Gaps = 5/256 (1%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS----EALKDAQE 69
+K ++ ++ EA E++ ++ E+++ ++K+ E+++ + E + QE
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 70 KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
++ E+K + E ++ +I EE++ + +E++ +K+ + E+ E E +
Sbjct: 524 EMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 130 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 189
E + ++ EEK+ QE +++E + + ++ + K E K+ E ++ EE+ E +
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 190 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
+R+ E+++R ++ ++ + +K EE++ +K++E E + E + +
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 250 EKSIDDLEEKVAHAKE 265
E + EEK+ +E
Sbjct: 703 EVRLRQQEEKMQEHQE 718
Score = 76.6 bits (187), Expect = 2e-14
Identities = 64/280 (22%), Positives = 144/280 (51%), Gaps = 21/280 (7%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++ E+ + ++K++ E+++ + E ++
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIR 454
Query: 66 DAQEKLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ +EK + EK K + EA + +I+ EE++ +E++ +K+ E EK
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR 514
Query: 121 DESERGMKVIESRAQKDEEKMEIQEI-QLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+E +R + E +++E+ E +EI + KE H E+ RK EE K+ E +
Sbjct: 515 EEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE---KMWRQEEKMHDQ 569
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAE 236
EE+ E +V + EE++R ++ ++ E+K ++E+ EE++ +K+ E E
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIRE---QEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ + E + + E+ I + E+K+ +E+ +M+ +
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Score = 76.3 bits (186), Expect = 3e-14
Identities = 49/249 (19%), Positives = 123/249 (49%), Gaps = 17/249 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED------ 55
+ I+++ + ++ +E + E+ +K E+ +Q ++E+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E ++ +EK+ E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E E M E + + EEKM+ QE +++ + + ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLK 233
++ EE+ E ++ + EE+++ ++ ++ Q+E +E+E+++ +K++
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---------RQEEKMWEQEVRLRQQEEKMQ 714
Query: 234 EAETRAEFA 242
E + E A
Sbjct: 715 EHQEHLEAA 723
Score = 75.1 bits (183), Expect = 7e-14
Identities = 54/259 (20%), Positives = 130/259 (50%), Gaps = 17/259 (6%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ ++ E + E++ ++ E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE------SERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 435 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEV---ARKLVIIESDLERAEERAELSEGQV 190
++ EEKM QE ++ E + I E+ R+ +E + + + ++ R +E+ E ++
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRAEFAERSVT 247
R+ EE++ ++ + E+K ++E+ R EE+I+ +K++E E + E
Sbjct: 553 RKQEEKMWRQEEKMH---DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 248 KLEKSIDDLEEKVAHAKEE 266
+ E+ + + EEK+ +E+
Sbjct: 610 EQEEKMGEQEEKMCEQEEK 628
Score = 73.6 bits (179), Expect = 2e-13
Identities = 56/288 (19%), Positives = 136/288 (47%), Gaps = 19/288 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 122 ESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
E E+ + E R + +++EK + QE ++ + + + K E K+ E E
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE---E 505
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV---------L 228
+ E+ ++ E + RQ +E++ ++ ++ E+ + QKE +E+E K+
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+K+ + E + E V + E+ I + EEK+ +E+ +M +
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Score = 70.1 bits (170), Expect = 2e-12
Identities = 64/244 (26%), Positives = 124/244 (50%), Gaps = 31/244 (12%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD + S
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQL--- 197
M QE + E E+ R+ EE+ + E + R EE E ++R+LEE++
Sbjct: 398 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 198 -RIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSID 254
+I +Q K E+K ++E R E+E K+ +K++E E + E + + E+ I
Sbjct: 451 EKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 255 DLEE 258
+ E+
Sbjct: 509 EQEK 512
Score = 66.6 bits (161), Expect = 2e-11
Identities = 65/299 (21%), Positives = 130/299 (43%), Gaps = 39/299 (13%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M E + ++ EE M +E +++ + + + + K E+ K+ E E+ E+R
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 183 AE------------------LSEGQVRQLEEQLRIMDQTL---------KALMAAEDKYS 215
E E ++R+ EE++R ++ + + + E+K
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQ 520
Query: 216 QKED--------RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
++E+ R +EEI +K+ E E + E + + E+ + D EEK+ +E+
Sbjct: 521 EQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Score = 62.8 bits (151), Expect = 3e-10
Identities = 67/272 (24%), Positives = 125/272 (45%), Gaps = 34/272 (12%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQ------------ERLATALQ--------KLEEAE 117
++ + +V L R +L+RA+ + L LQ ++EE E
Sbjct: 298 KSEIQLNVKELKR-------KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 350
Query: 118 ---KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + E M E + Q+ EEK++ QE +++E + + + K + E
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
+ R EE E ++R+ EE + ++ ++ L E + Q++ R +EE + +K++E
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEEEKIRE 468
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E R E E + + E+ I + EEK+ +E+
Sbjct: 469 QEKRQE-QEAKMWRQEEKIREQEEKIREQEEK 499
Score = 50.1 bits (118), Expect = 2e-06
Identities = 60/249 (24%), Positives = 125/249 (50%), Gaps = 30/249 (12%)
Query: 37 KQLEDELVSLQKKLKGT---EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR-RI 92
KQLE E L +L + EL++ A+ ++K + ++ T E D SL R
Sbjct: 215 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK-ERDALSLELYRN 273
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-EA 151
+ +EEL +L LQ +E +++SE + V E + + + K+ + + QL+ EA
Sbjct: 274 TITDEELKEKNAKLQEKLQLVE-----SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 328
Query: 152 KHIAEDADRKYEEVARKL--VIIESDL-----ERAEERAELSEGQVRQLEEQLRIMDQTL 204
H+ ++ + V+ KL + E++L ++ EE+ E ++++ EE+++ ++ +
Sbjct: 329 DHLGKEL----QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 205 K----ALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 257
+ + E+K ++E+ EE+++ + + E E + E + + E+ I +LE
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 258 EKVAHAKEE 266
EK+ H +E+
Sbjct: 445 EKM-HEQEK 452
Score = 35.8 bits (81), Expect = 0.044
Identities = 21/106 (19%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KMQ + ++ + E + E++ ++ E+ + ++K+ E+++ + E +
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
++ +EK+ E+K + E R++ EE++ QE L A+
Sbjct: 686 QEQEEKMRRQEEKMWEQEV-------RLRQQEEKMQEHQEHLEAAI 724
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 79.3 bits (194), Expect = 3e-15
Identities = 58/285 (20%), Positives = 139/285 (48%), Gaps = 23/285 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ ++ + E+ +K E+ +Q ++E+ ++K+ ++E+ +
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH-EQEEIWRQK 495
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQ------KLEE 115
E + + +EK+ E+K E + +I+ EE++ R +E++ + K+ E
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
EK +E +R + E + + EEK+ QE ++ + + + K +E K+ E
Sbjct: 556 QEKIWEEEKRQEQ--EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKA-----------LMAAEDKYSQKED---RY 221
+ EE+ + E ++R+ EE++R ++ + + E+K ++E+ R
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ K++E E + E + + E+ + + EEK+ +E+
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Score = 77.0 bits (188), Expect = 2e-14
Identities = 64/273 (23%), Positives = 133/273 (48%), Gaps = 18/273 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E + + + ++ EEE + QE + +K+ E E+
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY---EEVARKLVIIESDLER 178
+ E+ M E + +K EEK+ QE +++E + + + K EE R+ + + E+
Sbjct: 494 QKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 179 AEERAELSEGQVRQLEE------QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E+ ++ E + RQ +E + +I +Q K E Q+E R E+E +K+
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE-----EKM 607
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
+ E + E + + E+ I + EEK+ +E
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 74.3 bits (181), Expect = 1e-13
Identities = 53/249 (21%), Positives = 121/249 (48%), Gaps = 12/249 (4%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEK------ 76
EQ E +K E +Q E+++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVR 191
+ Q+ EEK+ QE +++E + + ++ + K E K+ E ++ EE E ++R
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 QLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
+ E+++R ++ ++ + +K EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 SIDDLEEKV 260
+ EEK+
Sbjct: 739 RLRQQEEKM 747
Score = 71.6 bits (174), Expect = 7e-13
Identities = 51/241 (21%), Positives = 125/241 (51%), Gaps = 10/241 (4%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA---DVASLN 89
+++ + E+++ ++K+ E+++ + E +++ +EK+ E+K + E + ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 90 RRIQLVEEELDRAQE-RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
+ ++ EEE + QE ++ +K+ E E+ E ++ E + Q+ EEKM QE ++
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALM 208
+E + ++ + K E K+ E + EE+ E ++ + EE+++ ++T +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET---MW 671
Query: 209 AAEDKYSQKEDR---YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
E+K ++E + EE+I+ + ++E E + E + + E+ + + EEK+ +E
Sbjct: 672 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Query: 266 E 266
+
Sbjct: 732 K 732
Score = 71.2 bits (173), Expect = 9e-13
Identities = 54/278 (19%), Positives = 137/278 (49%), Gaps = 31/278 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++ E+ + ++K++ E+++ + E ++
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIR 407
Query: 66 DAQEKLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ +EK + EK K + EA + +I+ EE++ ++++ +K+ E EK
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+E +R +++E+M QE ++ E + I ++ +E+ E + + E
Sbjct: 468 EEEKR----------QEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--------EEKIRKQE 509
Query: 181 ERAELSEGQVRQLEEQLRIMDQTL----KALMAAEDKYSQKEDRYEEEIKVLSDKLKEAE 236
E+ E ++R+ EE++R ++ + + + E+ + ++E +E+E +K +E E
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ E + + E+ + EEK+ +E+ + +
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Score = 70.5 bits (171), Expect = 2e-12
Identities = 47/214 (21%), Positives = 108/214 (50%), Gaps = 5/214 (2%)
Query: 12 KLDKENALDRAEQA--EADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE 69
K+ ++ + R E+ E +K E++ ++ ED++ ++K++ E+++ + E +++ +E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 70 KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
K + E+K E + +IQ EE++ +E++ + +E E+ E E M
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 130 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 189
E + Q+ EE M QE +++E + + + K E + E + EE+ E +
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Query: 190 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEE 223
+++ EE++R ++ + E + Q+E++ +E
Sbjct: 719 MQEQEEKMRRQEE---KMWEQEVRLRQQEEKMQE 749
Score = 70.1 bits (170), Expect = 2e-12
Identities = 62/251 (24%), Positives = 122/251 (48%), Gaps = 31/251 (12%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-------- 84
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 85 -VASL----------NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
A L NR Q EE++ R +E++ +K++E E+ E E ++ E +
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
++ EE M +E +++ + + + + K + E + R EE E ++R+L
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 194 EEQL----RIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVT 247
EE++ +I +Q K E+K ++E R E+E K+ +K++E E + E+ +
Sbjct: 397 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 248 KLEKSIDDLEE 258
+ E+ I + E+
Sbjct: 455 RQEEKIHEQEK 465
Score = 67.8 bits (164), Expect = 1e-11
Identities = 54/275 (19%), Positives = 134/275 (48%), Gaps = 20/275 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ +E +K E+ +I+E +E K E+ R+ E+ + E+ + R EE
Sbjct: 388 EKEEKIRELE---EKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQ----EAKMWRQEE 437
Query: 182 RAELSEGQVRQLEEQLRIMDQTL--KALMAAEDKYSQKEDRYEEEIKV--------LSDK 231
+ E ++R+ E+++ ++ + + + E+K ++E+ + +E K+ +K
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E E + E V + E+ I + EEK+ +E+
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 63.9 bits (154), Expect = 2e-10
Identities = 63/275 (22%), Positives = 125/275 (45%), Gaps = 21/275 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K ++QM ++A+ + E D + S + EL + + + D+Y E L
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 198
Query: 65 KDAQE--KLELAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ LEL TD E A L ++QLVE E Q + +KLE A+
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIESDLER 178
+ + +A+ D E+Q + K + E+ +R ++ K+ E ++
Sbjct: 259 PQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 179 AEERAELSEGQVRQLEEQLRIMDQTLK----ALMAAEDKYSQKED---RYEEEIKVLSDK 231
EE+ + E ++R+ EE++R ++ ++ + E+K ++E+ EE+++ +
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E E + E + + E+ I +LEEK+ H +E+
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKM-HEQEK 405
Score = 56.6 bits (135), Expect = 2e-08
Identities = 57/300 (19%), Positives = 136/300 (45%), Gaps = 33/300 (11%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADK--------KAAEDRSKQLEDELVSLQKKLKG 52
+ ++ K+Q ++++ +R Q + +K + E++ ++ E+++ ++K++
Sbjct: 274 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+++ + E + + +EK+ E+ + E + + EE++ R +E + +K
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 113 LEEAEKAADESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 168
+ E E+ E E+ + E R + +++EK + QE ++ + + + K E +K
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Query: 169 L-----VIIESDLERAEERAELSEGQVRQLEE---------QLRIMDQTLKALMAAEDKY 214
+ I E + R EE+ + E RQ E+ Q M + + + E+K
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 215 SQKEDRY---EEEIKVLSDKLKEAETRAEFAE---RSVTKLEKSIDDLEEKVAHAKEENL 268
++E++ EE+I+ +K+ E + E R K+ + EE+ +E+ +
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 79.0 bits (193), Expect = 5e-15
Identities = 62/281 (22%), Positives = 139/281 (49%), Gaps = 18/281 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ +++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E + + + ++ EEE + QE + +K+ E E+
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ E+ + + + +K EEK+ QE E H E+ R+ EE K+ E + EE
Sbjct: 480 QKEKMHE--QEKIRKQEEKVWRQE----EKMHDQEEKIREQEE---KMWRQEEKIREQEE 530
Query: 182 RAELSEGQVRQLEEQLRIMDQTL---KALMAAEDKYSQKEDRY---EEEIKVLSDKLKEA 235
+ E ++R+ EE ++ ++ + + M ++K ++E++ EE+I+ +K++E
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + E + + E+ + + EEK+ +E+ + + +
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Score = 74.3 bits (181), Expect = 1e-13
Identities = 59/278 (21%), Positives = 135/278 (48%), Gaps = 15/278 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 122 ESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL-----VII 172
E E+ + E R + +++EK + QE ++ + + + K E +K+ I
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQ--TLKALMAAEDKYSQKED---RYEEEIKV 227
E + R EE+ + E RQ EE++R ++ K M ++K ++E+ R EE++
Sbjct: 448 EQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
+K++E E + E + + E+ I + EEK+ +E
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Score = 72.4 bits (176), Expect = 4e-13
Identities = 66/265 (24%), Positives = 128/265 (48%), Gaps = 20/265 (7%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQ--------KLEEAE---KAAD 121
++ + +V L R+++ L +++L + L LQ ++EE E +
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 296
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ E M E + Q+ EEK++ QE +++E + + + K + E + R EE
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E ++R+LEE + ++ ++ L E + Q++ R +EE + +K++E E R E
Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEEEKIREQEKRQE- 413
Query: 242 AERSVTKLEKSIDDLEEKVAHAKEE 266
E + + E+ I + EEK+ +++
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKK 438
Score = 72.0 bits (175), Expect = 6e-13
Identities = 59/268 (22%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++LE+ + ++K++ E+++ +
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRLEEMMWEKEEKIRELEEKMHE------ 388
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ E+K + E R+ Q E ++ R +E++ +K+ E EK E
Sbjct: 389 --QEKIREQEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 126 GM----KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ K+ E ++++E+M QE +++E + I ++ +E+ K+ E + R EE
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQEE 502
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL---SDKLKEAETR 238
+ E ++R+ EE++ ++ ++ E+K ++E++ E+ +++ +K+ E E +
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIR---EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E+ + + E+ I + EEK+ KE+
Sbjct: 560 MQEQEK-MRRQEEKIREQEEKIREQKEK 586
Score = 71.6 bits (174), Expect = 7e-13
Identities = 52/253 (20%), Positives = 124/253 (49%), Gaps = 10/253 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ ++ + E+ +K E+ +Q ++E+ ++K++ ++E+ +
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 481
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + + QEK+ E+K E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 482 EKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E M+ E + + EEKM+ QE ++ + I E ++ E+ + I E+ E
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK----IREQEEKIWE 596
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ E Q ++EQ M + + + E+K ++E++ + +K+ E E R
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ----EEKMWEQEVRLRQ 652
Query: 242 AERSVTKLEKSID 254
E + + ++ ++
Sbjct: 653 QEEKMQEHQEHLE 665
Score = 69.7 bits (169), Expect = 3e-12
Identities = 59/275 (21%), Positives = 127/275 (46%), Gaps = 30/275 (10%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ ++ E + E++ ++ E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 374 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
++ E+KM QE ++ E + I E+ R+ +E ++ R EE+ E RQ
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQE----------EMWRQEEKIREQEEIWRQK 481
Query: 194 E---EQLRIMDQTLKALMAAEDKYSQKED---------RYEEEIKVLSDKLKEAETRAEF 241
E EQ +I Q K E + Q+E R EE+I+ +K++E E +
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 242 AERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + + E+ + + EEK+ ++ ++ +Q
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Score = 67.8 bits (164), Expect = 1e-11
Identities = 55/263 (20%), Positives = 131/263 (49%), Gaps = 8/263 (3%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDA--QEKL 71
+K ++ ++ EA E++ ++ E+++ +KK+ E+++ + + ++ QE+
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Query: 72 ELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
E+ ++ E + + +E++ + +E++ +K+ + E+ E E M E
Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
Query: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVR 191
+ ++ EEK+ QE +++E + + ++ + K E K+ E + R EE+ E ++R
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKIREQEEKIR 581
Query: 192 QLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKL 249
+ +E++R +Q K E Q+E E+E K+ +K+ E E + + E + +
Sbjct: 582 EQKEKIR--EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 250 EKSIDDLEEKVAHAKEENLSMHQ 272
E+ + + E ++ +EE + HQ
Sbjct: 640 EEKMWEQEVRL-RQQEEKMQEHQ 661
Score = 66.6 bits (161), Expect = 2e-11
Identities = 51/242 (21%), Positives = 118/242 (48%), Gaps = 14/242 (5%)
Query: 5 KKKM--QMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
+KKM Q K+ ++ + E+ + ++ K E E + QK+ ++++ K E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+ +EK+ E+K + E + +I+ EE++ +E++ + ++E E+ E
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M+ + + ++ EEK+ QE +++E K + + K E K+ E ++ EE+
Sbjct: 556 QEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 183 AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAE 240
E ++ + EE+++ ++ ++ Q+E +E+E+++ +K++E + E
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMR---------RQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Query: 241 FA 242
A
Sbjct: 666 AA 667
Score = 63.9 bits (154), Expect = 2e-10
Identities = 62/265 (23%), Positives = 124/265 (46%), Gaps = 21/265 (7%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M E + ++ EE M +E +++ + + + + K E+ K+ E E+ E+R
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399
Query: 183 AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL---------SDKLK 233
E E ++R+ E++ +Q K + E+K ++E++ E+ K + +K++
Sbjct: 400 QE--EEKIREQEKR---QEQEAK-MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
Query: 234 EAETRAEFAERSVTKLEKSIDDLEE 258
E E R E + + + E+ I + EE
Sbjct: 454 EEEKRQE--QEEMWRQEEKIREQEE 476
Score = 60.8 bits (146), Expect = 1e-09
Identities = 61/278 (21%), Positives = 122/278 (43%), Gaps = 27/278 (9%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K ++QM ++A+ + E D + S + EL + + + D+Y E L
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 198
Query: 65 KDAQE--KLELAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ LEL TD E A L ++QLVE E Q + +KLE A+
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIESDLER 178
+ + +A+ D E+Q + K + E+ +R ++ K+ E ++
Sbjct: 259 PQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 179 AEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE+ + E ++R+ EE++R ++ ++ Q+E +E+E +K++ E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRR---------QEEMMWEKE-----EKMRRQEEM 357
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + +LE+ + + EEK+ +E+ ++ +Q
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Score = 33.9 bits (76), Expect = 0.17
Identities = 18/108 (16%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL---EDELVSLQKKLKGTEDELDKYSE 62
++ + ++ +E ++ E+ K+ ++ +++ E+++ ++ ++ E+++ + E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
+ + +EK++ E+K E + R++ EE++ QE L A+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 79.0 bits (193), Expect = 5e-15
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 23/265 (8%)
Query: 9 QMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ 68
QML L +R + E + E+R ++ E+ L +++L+ E+ L + E L + +
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE 247
Query: 69 EKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
E+L E++ + E + R++ EE L +ERL ++L E E+ E E ++
Sbjct: 248 ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLR 307
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E R + EE++ QE +L E + + +R EEV + L + ER +E E
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKL-PGQERLLEEVEKLL-----EQERRQEEQERLLE 361
Query: 189 QVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE-EEIKVLSDKL---------KEAETR 238
+ R LEE +++Q + L +++ Q+E E E ++ L L + AE R
Sbjct: 362 RERLLEEVEELLEQ--ERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPR 419
Query: 239 AEFAE-----RSVTKLEKSIDDLEE 258
+ F E +S +LE+ + +L++
Sbjct: 420 SGFEELNNENKSTLQLEQQVKELKK 444
Score = 72.4 bits (176), Expect = 4e-13
Identities = 61/279 (21%), Positives = 132/279 (47%), Gaps = 12/279 (4%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++K+++ + + ++ + + E+R ++ E+ L +++L+ E+ L + E
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L++ +E+L E++ + E + R+ EE L +ERL ++L E E+ E
Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQ 288
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E ++ E R + EE++ QE +L ++ + + E +R E+ KL E LE E+
Sbjct: 289 EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKL 346
Query: 183 AELSEGQVRQLEEQLRIMD-----QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
E Q R+ EEQ R+++ + ++ L+ E Q E +++E ++L+E E
Sbjct: 347 LE----QERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELER 402
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E ++ + E++ + + L + Q + +
Sbjct: 403 MLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
Score = 68.9 bits (167), Expect = 5e-12
Identities = 68/278 (24%), Positives = 119/278 (42%), Gaps = 20/278 (7%)
Query: 10 MLKLDKENALDRAEQAEADKKAAE---DRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
+ KL + A A + A E D + L EL S+ ++L+ + S +
Sbjct: 137 LFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR 196
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+E+L E++ + E + R+ EE L +ERL ++L E E+ E E
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
+ E R + EE++ QE +L E + + + + E +L E L EER
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316
Query: 187 EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
E ++R+ EE+L E + ++R EE+ +KL E E R E ER +
Sbjct: 317 EERLREQEERL------------CEQEKLPGQERLLEEV----EKLLEQERRQEEQERLL 360
Query: 247 TKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ E+ ++++EE + + +TL EL +
Sbjct: 361 ER-ERLLEEVEELLEQERLRQQDERLWQQETLQELERL 397
Score = 38.9 bits (89), Expect = 0.005
Identities = 38/193 (19%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
D+ + R E+L+ + LA AL E+ + R K+E+
Sbjct: 68 DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLV----RTSKEEK 123
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRI 199
K EI +Q K + + + ++ E +A + S +E+ ++ ++ + QL+
Sbjct: 124 KHEIHLVQ-KLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQA 182
Query: 200 MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
+ + L + ++ EE ++ ++L+E E R E + + E+ + + EE+
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEER 242
Query: 260 VAHAKEENLSMHQ 272
+ +EE L H+
Sbjct: 243 LCE-QEERLREHE 254
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 78.6 bits (192), Expect = 6e-15
Identities = 63/277 (22%), Positives = 129/277 (46%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
+++ + +E L +A++ E K+ E QL++EL + ++ + + E D+ ++ +
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
++ K LA ++ EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR-KLVIIESDLERAEERAE 184
+ + S AQK+E + E Q KE K ++ + + + + +E+ + + EE+ +
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 185 LSEGQVRQLEEQLRIMDQTLKALMAAED-------KYSQKEDRYEEEIKVLSDKLKEAET 237
+ + +Q+R ++ LK ++ D +Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
A+ A S KL++ ++D E E S+ L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 64.7 bits (156), Expect = 9e-11
Identities = 77/326 (23%), Positives = 152/326 (46%), Gaps = 46/326 (14%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL----QKKLKGTEDELDK 59
++K + L+ E + E+ E + +A ED +LE L ++ ++ L+G +++ ++
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 60 YSEAL-----------KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
+ L +D +++ +A E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKYEEV 165
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R+ ++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 166 ARKLV--IIESDLERA---EERAELSEGQVRQLEEQLR--------IMDQTLKALMA--- 209
+L I S + A EE+ L E ++ QLEE+L I D+ KA +
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRL-EARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 210 ------AEDKYSQKED----RYEEEIKVLSDKLKEAE-TRAEFAERSVTKLEKSIDDLEE 258
E ++QK + + E + K L KL+E E T + S+T LE I LEE
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 259 KVAHAKEENLSMHQMLDQTLLELNNM 284
++ + +E + + + +T +L ++
Sbjct: 1822 QLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 64.3 bits (155), Expect = 1e-10
Identities = 60/283 (21%), Positives = 125/283 (44%), Gaps = 38/283 (13%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEA-----------DKKAAEDRSKQLEDELVSLQKKL 50
++ ++K+Q+ K+ E L + E+ + +KK EDR + L ++K
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 51 KGTEDELDKYSEALKDAQEKLELAEKK--------------ATDAEADVASLNRRIQLVE 96
K +K+ + D +E+L EK+ +TD +A L +I ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+L + +E L AL ++EE + + + ++ +ES+ + +E +E + +A+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQ 216
D + E + +L E L+ + EL + E+++ I+ +TL E++
Sbjct: 1136 DLGEELEALKTEL---EDTLDSTAAQQELRS----KREQEVNILKKTL------EEEAKT 1182
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
E + +E + S ++E + E +R LEK+ LE +
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENE 1225
Score = 63.9 bits (154), Expect = 2e-10
Identities = 59/289 (20%), Positives = 131/289 (45%), Gaps = 14/289 (4%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
K+ Q + + K+ + A+ EA + + Q +EL ++ K + L+K + L+
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATAL-QKLEEAEKAAD 121
+ + +L K + D ++++ +EL ER+ T L K+ + + D
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD------ 175
+ +S++ K + E QL++ + + ++ +R+ ++ KL +E +
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 176 -LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
LE EE E Q+ L Q+ M + ++ + + + + + +++++ LS + +E
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEE--NLSMHQ-MLDQTLLE 280
+ E++ T+L++ +DDL + H ++ NL Q DQ L E
Sbjct: 1404 KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE 1452
Score = 62.8 bits (151), Expect = 3e-10
Identities = 64/285 (22%), Positives = 128/285 (44%), Gaps = 30/285 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKK--AAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+K +Q+ + ++E E + +K AAE+R ++E L + +++L +
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
Query: 62 EALKDAQE-------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
E +A+E K + E+ D EA V R Q ++ E + Q+ + ++LE
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 115 EAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKY-------EE 164
E E A + + E++ +K EE+ +E Q +L + K + ED ++ EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 165 VARKLVII----ESDLERAEERAELSEGQVRQLEEQLRIMD-------QTLKALMAAEDK 213
++ L + E+ + EER E Q ++LE+ R ++ + L A +
Sbjct: 1014 KSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+ + EEE++ +++E + A + + +LE I +L+E
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Score = 61.6 bits (148), Expect = 7e-10
Identities = 71/307 (23%), Positives = 135/307 (43%), Gaps = 39/307 (12%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDEL--------------VSLQKKLKGTEDE-LDKY 60
E +R + +A+KK + ++LE++L V+ + KLK E+E +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 61 SEALKDAQEKLELAEKKA------TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+ K A+EK L ++ A T+ E SL + E + +ERL ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 115 EAEKA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----R 160
E EK D ++ ++ E +AQ E KM++ +E+Q A+ E A +
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
K E+ ++ ++ DLE +E Q R L E+L + L+ + + + +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 221 YEEEIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMH---QMLDQ 276
E+E+ +L L +EA+T + K +++++L E++ K ++ Q L+
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 277 TLLELNN 283
EL N
Sbjct: 1225 ERGELAN 1231
Score = 60.1 bits (144), Expect = 2e-09
Identities = 52/252 (20%), Positives = 116/252 (46%), Gaps = 13/252 (5%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-EKLELAEKKATDAE--ADVASLN 89
E+ E+ELV +++K E+ L + EKL+L E+ + E A+ L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
R+ ++EL+ L ++EE E+ + K ++ Q+ EE++E +E +
Sbjct: 904 ARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA 209
+ + + K +++ + +I+E + + +L E ++ + L ++ K+L
Sbjct: 961 KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL-- 1018
Query: 210 AEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269
++ ++++E I L ++L+ E + + E++ KLE DL +++A + +
Sbjct: 1019 -----AKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 270 MHQMLDQTLLEL 281
+ L + EL
Sbjct: 1074 LKMQLAKKEEEL 1085
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/263 (21%), Positives = 123/263 (46%), Gaps = 21/263 (7%)
Query: 12 KLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
KL K+ +AL+ Q + E+R K +SL KLK EDE + + E L++ +E
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQK------LSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 71 LELAEKKATDAEADVASLNRR-------IQLVEEELDRAQERLATALQKLEEAEKAADES 123
EK+ A VA + ++ ++ EE + Q+ L Q+ EE A D+
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + +++ E +K++++ + I + + AEER
Sbjct: 1412 EK----TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA--KYAEER- 1464
Query: 184 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
+ +E + R+ E + + + L+ M + + + ++ E++ L + E
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 244 RSVTKLEKSIDDLEEKVAHAKEE 266
+S LE+ +++++ ++ ++E
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDE 1547
Score = 55.8 bits (133), Expect = 4e-08
Identities = 53/302 (17%), Positives = 138/302 (45%), Gaps = 19/302 (6%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
++ K ++Q D LD Q+ + + + + QL E ++ K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + L A ++A + +A++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IESRAQKDEEKMEIQEIQL--------KEAKHIAEDADRKYEEVARK 168
++ MK +E Q E+ E+ L ++ + E ++ K +++ R+
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 169 LVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL 228
+ +E++LE ++ ++ ++LE L+ ++ + + D+ ++ + + ++K
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 229 SDKL-------KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
+L +E +A+ E+ + +E + L+E++A A+ Q D+ E+
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 282 NN 283
N
Sbjct: 1711 AN 1712
Score = 52.8 bits (125), Expect = 3e-07
Identities = 69/271 (25%), Positives = 123/271 (45%), Gaps = 25/271 (9%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
L K+ + EA + E+R + L+ E +KK++ EL++ E + A++K
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAE----KKKMQQNIQELEEQLEEEESARQK 961
Query: 71 LELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
L+L EK T+A+ +I L ++ A+E+ + E +E E+ +
Sbjct: 962 LQL-EKVTTEAKLKKLE-EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL--ERAEERAELSE- 187
K + K E L+E E ++ E+ RKL +DL + AE +A+++E
Sbjct: 1020 -----KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 188 -GQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
Q+ + EE+L+ AL E++ +QK + ++I+ L ++ E + E S
Sbjct: 1075 KMQLAKKEEELQ------AALARVEEEAAQK-NMALKKIRELESQISELQEDLESERASR 1127
Query: 247 TKLEKSIDDLEEKVAHAKEENLSMHQMLDQT 277
K EK DL E++ K E + LD T
Sbjct: 1128 NKAEKQKRDLGEELEALKTE---LEDTLDST 1155
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/277 (20%), Positives = 122/277 (44%), Gaps = 21/277 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED-------- 55
+ K L+ ++ + ++ K + + KQ+EDE S +++L+ E+
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 56 ------ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
++ + ++D+ LE AE+ + D+ L++R + D+ ++
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
Q+L++ D + +E + +K ++ + E + AK+ AE+ DR E AR+
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQL--LAEEKTISAKY-AEERDRA-EAEAREK 1474
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
L RA E A + ++ +L +Q R ++ LM+++D + E+ + L
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFR---TEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+++E +T+ E E + E + LE + K +
Sbjct: 1532 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/209 (21%), Positives = 97/209 (46%), Gaps = 22/209 (10%)
Query: 2 DAIKK-KMQMLKLDKENALDR--AEQAEADKKAAEDRSKQLEDEL--------------- 43
D +KK +Q+ +++ + L+R A++ E ++ E ++K+L+ +L
Sbjct: 1750 DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
Query: 44 VSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+L+ K+ E++LD ++ + A +++ EKK D V R + +++ D+A
Sbjct: 1810 TALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAS 1869
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY- 162
RL ++LEEAE+ A + + ++ + E + ++ K+ D +
Sbjct: 1870 TRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV 1929
Query: 163 --EEVARKLVIIESDLERAEERAELSEGQ 189
+ARK SD E + +A+ +E +
Sbjct: 1930 VPRRMARKGAGDGSD-EEVDGKADGAEAK 1957
Score = 29.6 bits (65), Expect = 3.1
Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMD-QTLKALMAAEDKYSQKE 218
R + +V L + + E + EL + + +QL + R+ + +TL++ + AE Q++
Sbjct: 829 RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+ E E+ +++L+ T + +LE+ DLE +V +EE H ++
Sbjct: 889 LQAETELCAEAEELRARLTAKK------QELEEICHDLEARV--EEEEERCQHLQAEKKK 940
Query: 279 LELN 282
++ N
Sbjct: 941 MQQN 944
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 78.6 bits (192), Expect = 6e-15
Identities = 59/268 (22%), Positives = 131/268 (48%), Gaps = 10/268 (3%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
+ Q L KE ++ + E ++K E K + E + Q+K ++++ + + + +
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDR-----AQERLATALQKLEEAEKAAD 121
+EK+ E+K D E + + R++ EE + QE +K +E EK
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ E M+ E R ++ E+KM +E ++E + ++ + K E K+ E ++ EE
Sbjct: 551 DQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETR 238
+ E ++ + EE+ ++ +Q + + E+K ++E++ EE+++ +K++E E +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQE-EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E + + E+ + EEK+ +E+
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEK 696
Score = 75.5 bits (184), Expect = 5e-14
Identities = 56/257 (21%), Positives = 128/257 (49%), Gaps = 16/257 (6%)
Query: 36 SKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE-----LAEKKATDAEADVASLNR 90
+++L+ + LQ+KL+ E E + +K+ + KLE L + + + ++
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 91 RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKE 150
++ E+++ + +E++ ++L E E E E M+ E R ++ E+++ QE +L+E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 151 AKHIAEDADRKYE------EVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTL 204
K + E ++ E E K+ E + R EER E Q+R+ E+++R ++ +
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 205 ----KALMAAEDKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
+ L E++ ++E +E+E K+ ++++E E + E ++ + E+ + EE
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 260 VAHAKEENLSMHQMLDQ 276
+ +E+ ++ +Q
Sbjct: 422 MWEQEEKEWQQQRLPEQ 438
Score = 73.9 bits (180), Expect = 1e-13
Identities = 62/250 (24%), Positives = 122/250 (48%), Gaps = 26/250 (10%)
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQ------------LVEEELD 100
T +EL K + L QEKL LAE + ++ + +V L R+++ ++EE+
Sbjct: 181 TNEELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
Query: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
R +E L +K+ + E+ E ++ E + ++ EEKM QE +L+E + + ++
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTL----KALMAAEDKYSQ 216
+ E +KL E ++ EE+ E ++R+ EE++ ++ L K + E K
Sbjct: 298 ELRE-QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD--LEEKVAHAKEENLSMHQML 274
+E+R E+ ++L+E E R E+ + EK ++ + E+ +EE +M +
Sbjct: 357 QEERMWEQ----DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 275 DQTLLELNNM 284
++ + NM
Sbjct: 413 EKMQKQEENM 422
Score = 71.2 bits (173), Expect = 9e-13
Identities = 58/253 (22%), Positives = 125/253 (49%), Gaps = 10/253 (3%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
K + +L ++ L +E++E E + K + + Q + ++E+ + E L++
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
++K+ E+K E + +++ EE++ R ++RL ++L E EK E ++
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK- 304
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
++ E + Q+ EEKM QE +++E + + + E +++ E + EER
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 187 EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
+ ++R+ EE++R ++ M +++ Q+E+R E K K++E E E +
Sbjct: 365 DERLREKEERMREQEK-----MWEQEEKMQEEERIREREK----KMREEEETMREQEEKM 415
Query: 247 TKLEKSIDDLEEK 259
K E+++ + EEK
Sbjct: 416 QKQEENMWEQEEK 428
Score = 69.7 bits (169), Expect = 3e-12
Identities = 54/236 (22%), Positives = 112/236 (47%), Gaps = 8/236 (3%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E ++ E+ KK + K E++ Q+K ++E + E +++ ++K+ E
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ + E + +++ EE++ +E++ +K+ E E+ E E K+ E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 136 --KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
+ EEKM+ QE ++ E + + + K E K+ E + EE+ + E ++R+
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 194 EEQLRIMDQTL----KALMAAEDK-YSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
EE++R ++ + + + E+K + Q+E R +EE ++ K K E E ER
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE-RIRDQKEKMQERLPEHEER 748
Score = 66.6 bits (161), Expect = 2e-11
Identities = 62/284 (21%), Positives = 134/284 (47%), Gaps = 35/284 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADK-KAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++ ++ + +KE E E K + E++ ++ E+++ ++K++ E+++ + E
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-- 121
L + ++++ E+K D E + + R++ EE + R QE++ +K++E E+ +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQEEKMQEEERIRERE 398
Query: 122 ----ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR-----KYEEVARKLVII 172
E E M+ E + QK EE M QE + + + + E ++ K +E K+
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Query: 173 ESDLERAEE------------RAELSEGQVRQLEEQLRIMDQTL----KALMAAEDKYSQ 216
E + EE + E Q+ + EE++R +Q + + + +++ +
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
KE+R E+ K+ + K E E+ + EK D EEK+
Sbjct: 519 KEERMREQKKMWQQEEKMRE------EKKTQEQEKKTWDQEEKM 556
Score = 66.2 bits (160), Expect = 3e-11
Identities = 59/276 (21%), Positives = 128/276 (46%), Gaps = 14/276 (5%)
Query: 15 KENALDRAEQAEADKKA-AEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE- 72
+E D+ E +KK +++ ++ ED++ ++K++ E ++ E + + E+L
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 73 ----LAEKKATDAEADVASLNRRIQLVE------EELDRAQERLATALQKLEEAEKAADE 122
+ E+K + + ++ Q E EE R +ER+ +K+ E E+ E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY--EEVARKLVIIESDLERAE 180
E M+ E + ++ EEKM QE +++E + + + K +E K+ E + E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E+ + E ++ + EE++R ++ ++ +K EE+++ +K++E E +
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + E+ + EEK+ +E ++ DQ
Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Score = 65.9 bits (159), Expect = 4e-11
Identities = 53/225 (23%), Positives = 109/225 (48%), Gaps = 12/225 (5%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM+ K +E +Q E K E+R ++ E ++ ++ ++ E+++ + E +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEE--KMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEE--LDRAQERLATALQKLEEAEKAADE 122
++ +EK+ E+K + E + ++ EEE + +E + +K++E E+ E
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M+ E + ++ EEKM+ QE +++E + + + K E K+ E + EE+
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 183 ----AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEE 223
E GQ E++ RI DQ K +++ + E+R E
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEK----MQERLPEHEERCSE 751
Score = 64.3 bits (155), Expect = 1e-10
Identities = 61/244 (25%), Positives = 122/244 (50%), Gaps = 18/244 (7%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
E + ++ E+++ +K+L+ E EL + + L++ Q+KL E++ + E + ++
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKM 326
Query: 93 QLVEEELDRAQERLATALQKLEEAE-KAADESERGMKVIESRAQKDE-----EKMEIQEI 146
+ EE++ R +ERL +++ E E K D+ ER + E +K+E EKM QE
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 147 QLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE---RAELSEGQVRQLEEQ------L 197
+++E + I E ++K E + E +++ EE E E Q ++L EQ
Sbjct: 387 KMQEEERIRE-REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKV-LSDKLKEAETRAEFAERSVTKLEKSIDDL 256
M + + + E+K +E+ + +E K+ +K++E E + E + E+ + D
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 257 EEKV 260
EE++
Sbjct: 506 EERM 509
Score = 63.2 bits (152), Expect = 3e-10
Identities = 58/279 (20%), Positives = 130/279 (46%), Gaps = 10/279 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQA-EADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
D + ++ + ++ ++ D+ E+ E D++ E + E + + Q++ E + +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ D +EK+ E++ + E + ++ EE++ +E++ +K+ E E+
Sbjct: 546 EKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 121 DESERGMKVIESR--AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER 178
E E M E + Q++E+KM+ QE + E + ++ + K E K+ E +
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
Query: 179 AEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEA 235
EE+ + E ++R+ EE+++ ++ ++ E+K +E++ EE++ +K+
Sbjct: 665 QEEKMQGQEEKMREQEEKMQGQEEKMR---EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 721
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
E E ER + EK + L E E L ++L
Sbjct: 722 EEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVL 760
Score = 60.5 bits (145), Expect = 2e-09
Identities = 61/279 (21%), Positives = 135/279 (48%), Gaps = 19/279 (6%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE-----DELVSLQKKLKGTEDELDK 59
++KMQ + +E E+ E ++ E KQ E +E Q++L +++L +
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNR-----RIQLVEEELDRAQERLATALQKLE 114
E +++ +EK+ E+K D E + +++ E+++ +E++ QK+
Sbjct: 445 -QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY--EEVARKLVII 172
+ E+ E + ++ E R ++++KM QE +++E K E + + EE R+ +
Sbjct: 504 DQEERMWEQDERLREKEER-MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR-YEEEIKVL--- 228
++ E E+ Q +++EQ M + + + E+K ++E++ +E+E K+
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 229 -SDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
DK++E E E + + E+ + + EEK+ +E+
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Score = 55.1 bits (131), Expect = 7e-08
Identities = 56/259 (21%), Positives = 121/259 (46%), Gaps = 19/259 (7%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS-----EALKDAQEKLELA 74
+R + E + E + + E+ + ++L+ E+ + + E +E++
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 75 EKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM----KVI 130
EKK + E + ++Q EE + +E+ Q+L E ++ E E+ K+
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 131 ESRAQ-KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 189
E + +D+E+M QE ++ + + E D+ +E+ K+ E + EER + +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-EEKMRDQEQKMWDQEERMWEQDER 515
Query: 190 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVT 247
+R+ EE++R K + E+K +++ E+E K +K++E E E E+ +
Sbjct: 516 LREKEERMR----EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 570
Query: 248 KLEKSIDDLEEKVAHAKEE 266
+ E+ + + EEK+ +E+
Sbjct: 571 EEEEMMREQEEKMQEQEEK 589
Score = 35.4 bits (80), Expect = 0.057
Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 29/209 (13%)
Query: 65 KDAQEKLELAEKKATD-AEADVASLNRRI-QLVEEELDRAQERLATALQKLEEAEKAADE 122
K Q KL A+KK TD + ++A + R +++++ T + E
Sbjct: 16 KTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKA 75
Query: 123 SERGMKVIESRAQKDEEKMEI---QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
S + + + + + + I Q+ +L+ A + ++DA RK+E + +L +
Sbjct: 76 SHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE---------DGNLGES 126
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRA 239
++ A +L + +AL +A + +K DRY EE+ D L
Sbjct: 127 KDLA-------GRLHHSWHFAGELQRAL-SAVSTWHKKADRYIEELTKERDALS-----L 173
Query: 240 EFAERSVT--KLEKSIDDLEEKVAHAKEE 266
E ++T +L+K +L+EK+ A+ E
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESE 202
Score = 32.3 bits (72), Expect = 0.48
Identities = 52/246 (21%), Positives = 95/246 (38%), Gaps = 46/246 (18%)
Query: 75 EKKATDAEADVASLNRRIQLVEEE---LDRAQERLATALQKLEEAEKAADESERG-MKVI 130
EKKA+ + +L R I+ + L + L TAL ++A + ++ G K +
Sbjct: 72 EKKASHQHQE--ALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR----------------------- 167
R + L + ADR EE+ +
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 168 -----KLVIIES----------DLERAEERAE--LSEGQVRQLEEQLRIMDQTLKALMAA 210
KL + ES +L+R ERA+ L + Q L+E++ ++ L+
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 211 EDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
K +K R EE ++ K++E E + E+ + + EK + + E+++ K+
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
Query: 271 HQMLDQ 276
QM +Q
Sbjct: 310 EQMQEQ 315
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 78.6 bits (192), Expect = 6e-15
Identities = 71/281 (25%), Positives = 135/281 (48%), Gaps = 30/281 (10%)
Query: 3 AIKKKMQMLKLDKENALDR----AEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
A++ ++Q LK E A + A+QA K+ A LED LQK L LD
Sbjct: 315 ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL-----LD 369
Query: 59 KY-SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K ++ +++ Q +L++ +K+++ AE + S +R++ + EL A L+KLE ++
Sbjct: 370 KQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEA-------LRKLENSD 422
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K E + K + + K + ++ + Q +E I + +E + L L+
Sbjct: 423 K---EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 479
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+++E +L EG++ L ++ + D+TLK + + EEE + L +L+ T
Sbjct: 480 KSKEHEKLMEGELEALRQEFKKKDKTLK----------ENSRKLEEENENLRAELQCCST 529
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+ E + ++ I DL +++A KE +S+ LD+ L
Sbjct: 530 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKAL 570
Score = 67.8 bits (164), Expect = 1e-11
Identities = 69/304 (22%), Positives = 137/304 (45%), Gaps = 29/304 (9%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D +K + L LDK+ A D ++ + + + + S E E S +K+++ EL S
Sbjct: 357 DTQRKLQKGLLLDKQKA-DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL---S 412
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATALQK-LEEAE 117
EAL+ KLE ++K+ + VA + ++ + + + R Q + L++ L+EA
Sbjct: 413 EALR----KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEAT 468
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE----VARKLVIIE 173
K ++ +K + + E ++E + K+ ++ RK EE + +L
Sbjct: 469 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 528
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY------EEEIKV 227
+ LE + + S+ ++ L +++ + ++L +L A DK QKE Y +E
Sbjct: 529 TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA 588
Query: 228 LS-------DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
LS D L +A + L++S+ +EK A +EE ++ + + + E
Sbjct: 589 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 648
Query: 281 LNNM 284
L +
Sbjct: 649 LRKL 652
Score = 54.7 bits (130), Expect = 9e-08
Identities = 60/278 (21%), Positives = 117/278 (42%), Gaps = 60/278 (21%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE- 69
L+ D + A E K +++ K +E EL +L+++ K + L + S L++ E
Sbjct: 460 LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENEN 519
Query: 70 ----------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+LE + K ++ + LN+ I L +E L Q +L ALQK
Sbjct: 520 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------- 572
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
EK +Q KEA Y+ ++RK + DL +A
Sbjct: 573 -------------------EKHYLQTTITKEA----------YDALSRKSAACQDDLTQA 603
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAE 236
E+ + + L++ +L ++K +Q E+ YEE +K L+ +L++
Sbjct: 604 LEKLNHVTSETKSLQQ----------SLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 653
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ +E V +K ++++ +V ++++ + +ML
Sbjct: 654 GFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKML 691
Score = 54.3 bits (129), Expect = 1e-07
Identities = 59/290 (20%), Positives = 132/290 (45%), Gaps = 27/290 (9%)
Query: 22 AEQAEADKKAAEDRSKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQE---KLEL-- 73
+E+ E KK + +Q + + + + Q +K EL+ SE ++ + KLEL
Sbjct: 153 SEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL 212
Query: 74 -AEKKATDA-----EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++ T A + D+ L R+Q ++ E Q+ + L+E ++ E E+ +
Sbjct: 213 HGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKL 272
Query: 128 KVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVI----IESDLERAEE 181
+++ K E+++E Q+ E + ++A D+ E + L +++ LE A++
Sbjct: 273 TQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQ 332
Query: 182 RAELSEGQVRQLEEQLRI----MDQTLKALMAAEDKYSQKEDRYEE---EIKVLSDKLKE 234
+ L+ Q Q +E+ + ++ T + L QK D +E E+++L +
Sbjct: 333 QERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM 392
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
AE + V +L + + K+ ++ +E + + + + +++N+M
Sbjct: 393 AEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDM 442
Score = 38.1 bits (87), Expect = 0.009
Identities = 55/294 (18%), Positives = 117/294 (39%), Gaps = 37/294 (12%)
Query: 13 LDKENALDRAE----QAEADKKAAEDR-------SKQLEDEL----VSLQKKLKGTEDEL 57
L+KE AL + QA+ DK +++ +K+ D L + Q L ++L
Sbjct: 548 LNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKL 607
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
+ + K Q+ L ++K E ++ + R++ + EL + + + ++ +
Sbjct: 608 NHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFD 667
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K +E + + + Q D + + +E QL+E + E A K ++E D E
Sbjct: 668 KKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQE---------EMAALKENLLEDDKE 718
Query: 178 RA--------EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
++ L G ++ + ++Q K A +K + + I LS
Sbjct: 719 PCCLPQWSVPKDTCRLYRGN----DQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLS 774
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ TRA + + S L + H ++EN + + +++ ++ N
Sbjct: 775 GEKDREPTRAS-SPNTTRPSSPSHSHLHSVMVHLQQENKKLKKEIEEKKMKAEN 827
Score = 38.1 bits (87), Expect = 0.009
Identities = 26/139 (18%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
DA+ +K + D AL++ ++ +K L+ L Q+K E+E+ Y
Sbjct: 587 DALSRKSAACQDDLTQALEKLNHVTSE-------TKSLQQSLTQTQEKKAQLEEEIIAYE 639
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +K +L ++E +V + +++++ + ++ + Q++ L+ L E+
Sbjct: 640 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 699
Query: 122 ESERGMKVIESRAQKDEEK 140
E + M ++ +D+++
Sbjct: 700 EFQEEMAALKENLLEDDKE 718
Score = 34.7 bits (78), Expect = 0.098
Identities = 49/214 (22%), Positives = 89/214 (41%), Gaps = 12/214 (5%)
Query: 69 EKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
EKL LA+++ A +ASL R + L D+ Q L+ ++ LE K G+
Sbjct: 10 EKLHLAQEQLALAGDKIASLERSLNLYR---DKYQSSLSN-IELLECQVKMLQGELGGIM 65
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E + D K+ I +H ++ ++ EV +K+ + ++ + S
Sbjct: 66 GQEPENKGDHSKVRIYTSPCMIQEH--QETQKRLSEVWQKVSQQDDLIQELRNKLACSNA 123
Query: 189 QVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTK 248
V + E+ L I Q A A +Y E+IK + LK + + + V +
Sbjct: 124 LVLEREKAL-IKLQADFASCTATHRYPPSSSEECEDIKKI---LKHLQEQKDSQCLHVEE 179
Query: 249 LEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
+ + DL ++ E+ ++ M D LEL+
Sbjct: 180 YQNLVKDLRVELEAVSEQKRNI--MKDMMKLELD 211
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 78.6 bits (192), Expect = 6e-15
Identities = 71/281 (25%), Positives = 135/281 (48%), Gaps = 30/281 (10%)
Query: 3 AIKKKMQMLKLDKENALDR----AEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
A++ ++Q LK E A + A+QA K+ A LED LQK L LD
Sbjct: 460 ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL-----LD 514
Query: 59 KY-SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K ++ +++ Q +L++ +K+++ AE + S +R++ + EL A L+KLE ++
Sbjct: 515 KQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEA-------LRKLENSD 567
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K E + K + + K + ++ + Q +E I + +E + L L+
Sbjct: 568 K---EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 624
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+++E +L EG++ L ++ + D+TLK + + EEE + L +L+ T
Sbjct: 625 KSKEHEKLMEGELEALRQEFKKKDKTLK----------ENSRKLEEENENLRAELQCCST 674
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+ E + ++ I DL +++A KE +S+ LD+ L
Sbjct: 675 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKAL 715
Score = 67.8 bits (164), Expect = 1e-11
Identities = 69/304 (22%), Positives = 137/304 (45%), Gaps = 29/304 (9%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D +K + L LDK+ A D ++ + + + + S E E S +K+++ EL S
Sbjct: 502 DTQRKLQKGLLLDKQKA-DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL---S 557
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATALQK-LEEAE 117
EAL+ KLE ++K+ + VA + ++ + + + R Q + L++ L+EA
Sbjct: 558 EALR----KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEAT 613
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE----VARKLVIIE 173
K ++ +K + + E ++E + K+ ++ RK EE + +L
Sbjct: 614 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 673
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY------EEEIKV 227
+ LE + + S+ ++ L +++ + ++L +L A DK QKE Y +E
Sbjct: 674 TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA 733
Query: 228 LS-------DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
LS D L +A + L++S+ +EK A +EE ++ + + + E
Sbjct: 734 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 793
Query: 281 LNNM 284
L +
Sbjct: 794 LRKL 797
Score = 54.7 bits (130), Expect = 9e-08
Identities = 60/278 (21%), Positives = 117/278 (42%), Gaps = 60/278 (21%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE- 69
L+ D + A E K +++ K +E EL +L+++ K + L + S L++ E
Sbjct: 605 LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENEN 664
Query: 70 ----------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+LE + K ++ + LN+ I L +E L Q +L ALQK
Sbjct: 665 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------- 717
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
EK +Q KEA Y+ ++RK + DL +A
Sbjct: 718 -------------------EKHYLQTTITKEA----------YDALSRKSAACQDDLTQA 748
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAE 236
E+ + + L++ +L ++K +Q E+ YEE +K L+ +L++
Sbjct: 749 LEKLNHVTSETKSLQQ----------SLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 798
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ +E V +K ++++ +V ++++ + +ML
Sbjct: 799 GFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKML 836
Score = 54.3 bits (129), Expect = 1e-07
Identities = 59/290 (20%), Positives = 132/290 (45%), Gaps = 27/290 (9%)
Query: 22 AEQAEADKKAAEDRSKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQE---KLEL-- 73
+E+ E KK + +Q + + + + Q +K EL+ SE ++ + KLEL
Sbjct: 298 SEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL 357
Query: 74 -AEKKATDA-----EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++ T A + D+ L R+Q ++ E Q+ + L+E ++ E E+ +
Sbjct: 358 HGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKL 417
Query: 128 KVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVI----IESDLERAEE 181
+++ K E+++E Q+ E + ++A D+ E + L +++ LE A++
Sbjct: 418 TQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQ 477
Query: 182 RAELSEGQVRQLEEQLRI----MDQTLKALMAAEDKYSQKEDRYEE---EIKVLSDKLKE 234
+ L+ Q Q +E+ + ++ T + L QK D +E E+++L +
Sbjct: 478 QERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM 537
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
AE + V +L + + K+ ++ +E + + + + +++N+M
Sbjct: 538 AEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDM 587
Score = 48.5 bits (114), Expect = 7e-06
Identities = 60/340 (17%), Positives = 146/340 (42%), Gaps = 63/340 (18%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADK-------KAAEDRSKQLEDELVSLQKKLK----G 52
++ K + LK KE+ + EA + K ++ S++LE+E +L+ +L+
Sbjct: 616 LEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQ 675
Query: 53 TEDELDKYS-----------------EALKDAQEKLELAEKK------ATDAEADVASLN 89
E L+KY+ E+L Q +L+ A +K T + +L+
Sbjct: 676 LESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALS 735
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
R+ +++L +A E+L + + +++ +++ +E EE+M+ +L+
Sbjct: 736 RKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELR 795
Query: 150 EAKHIAEDA-------DRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQ 202
+ + +++ D+K EE++ +++ + + + E Q+R+ +E++ + +
Sbjct: 796 KLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKE 855
Query: 203 TLK-------------------ALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
L L D+ +++ ++ KV ++KL + R +
Sbjct: 856 NLLEDDKEPCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGN-QLREQV-- 912
Query: 244 RSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ + KL D L + H ++EN + + +++ ++ N
Sbjct: 913 KYIAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAEN 952
Score = 47.0 bits (110), Expect = 2e-05
Identities = 63/286 (22%), Positives = 121/286 (42%), Gaps = 16/286 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+ +KKK+ +L+ + E + + + + + ++ +LV L K EDE+ Y
Sbjct: 83 LQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILY 142
Query: 61 SEAL----KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
E + ++ EKL LA+++ A +ASL R + L D+ Q L+ ++ LE
Sbjct: 143 EEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYR---DKYQSSLSN-IELLECQ 198
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
K G+ E + D K+ I +H ++ ++ EV +K+ + +
Sbjct: 199 VKMLQGELGGIMGQEPENKGDHSKVRIYTSPCMIQEH--QETQKRLSEVWQKVSQQDDLI 256
Query: 177 ERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAE 236
+ + S V + E+ L I Q A A +Y E+IK + LK +
Sbjct: 257 QELRNKLACSNALVLEREKAL-IKLQADFASCTATHRYPPSSSEECEDIKKI---LKHLQ 312
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
+ + V + + + DL ++ E+ ++ M D LEL+
Sbjct: 313 EQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNI--MKDMMKLELD 356
Score = 43.5 bits (101), Expect = 2e-04
Identities = 53/264 (20%), Positives = 113/264 (42%), Gaps = 32/264 (12%)
Query: 28 DKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELA-----EKKATDA 81
D+ DR L +L+SLQ +K D + + L+D Q +E A +KK A
Sbjct: 3 DEAGERDREVSSLNSKLLSLQLDIKNLHDVCKRQRKTLQDNQLCMEEAMNSSHDKKQAQA 62
Query: 82 EA-----------------DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
A + L +++ ++++EL+ E L T+ L + + ++
Sbjct: 63 LAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQT 122
Query: 125 RGMKVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVA---RKLVIIESDLERAE 180
+ ++ + E+++ + E ++ ++ E E++A K+ +E L
Sbjct: 123 SDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYR 182
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE-AETRA 239
++ + S + LE Q++++ L +M E + K D + I ++E ET+
Sbjct: 183 DKYQSSLSNIELLECQVKMLQGELGGIMGQEPE--NKGDHSKVRIYTSPCMIQEHQETQK 240
Query: 240 EFAE--RSVTKLEKSIDDLEEKVA 261
+E + V++ + I +L K+A
Sbjct: 241 RLSEVWQKVSQQDDLIQELRNKLA 264
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/239 (18%), Positives = 103/239 (43%), Gaps = 19/239 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
DA+ +K + D AL++ ++ +K L+ L Q+K E+E+ Y
Sbjct: 732 DALSRKSAACQDDLTQALEKLNHVTSE-------TKSLQQSLTQTQEKKAQLEEEIIAYE 784
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +K +L ++E +V + +++++ + ++ + Q++ L+ L E+
Sbjct: 785 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 844
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E + M ++ +D+ +E + +D R Y + + +E + A++
Sbjct: 845 EFQEEMAALKENLLEDD-----KEPCCLPQWSVPKDTCRLYRGNDQIMTNLE---QWAKQ 896
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ +E QL EQ++ + L +D ++E K L +++E + +AE
Sbjct: 897 QKVANEKLGNQLREQVKY----IAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAE 951
Score = 39.3 bits (90), Expect = 0.004
Identities = 56/277 (20%), Positives = 112/277 (40%), Gaps = 54/277 (19%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAE-----------DRSKQLE-DELVSLQKK 49
D K++ + L+ D + ++ A + DKK A+ SKQ +L L+KK
Sbjct: 31 DVCKRQRKTLQ-DNQLCMEEAMNSSHDKKQAQALAFEESEVEFGSSKQCHLRQLQQLKKK 89
Query: 50 LKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEEL---------- 99
L + EL+ ++E L+ + L + +D+ L+ +L E+E+
Sbjct: 90 LLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILYEEEMGNH 149
Query: 100 -DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
+ E+L A ++L A ER + + + Q +E+ E Q+K
Sbjct: 150 NENTGEKLHLAQEQLALAGDKIASLERSLNLYRDKYQSSLSNIELLECQVK--------- 200
Query: 159 DRKYEEVARKLVIIESDL-----ERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 213
+++ +L + E + + S+ ++ ++ +T K L K
Sbjct: 201 ------------MLQGELGGIMGQEPENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQK 248
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
SQ++D +E L +KL + E+++ KL+
Sbjct: 249 VSQQDDLIQE----LRNKLACSNALVLEREKALIKLQ 281
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 76.6 bits (187), Expect = 2e-14
Identities = 76/312 (24%), Positives = 141/312 (45%), Gaps = 42/312 (13%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 647
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 648 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 707
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 708 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ-LEEQLRIMDQTLKALM 208
E ++ D D+K E+ R++ + + + ++ + + Q LEE R D +
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 826
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLK---EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
+D +K+DR EE + L + ++ E E E + T EK +++L + K+
Sbjct: 827 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 886
Query: 266 ENLSMHQMLDQT 277
E SM L T
Sbjct: 887 ELESMKAKLSST 898
Score = 67.0 bits (162), Expect = 2e-11
Identities = 61/295 (20%), Positives = 130/295 (44%), Gaps = 18/295 (6%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 586
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
D ++ +K ++ + + + +E L + K A + +L +E LE+
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 180 EERAELSEGQVRQLEE---QLRI---MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+E E Q+++ E + R M ++ L +Y + + + E+ L + LK
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 234 EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE----ENLSMHQMLDQTLLELNNM 284
E E ++ + +LE+ + D +KVA+ K E QML++ +N+
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNL 821
Score = 65.9 bits (159), Expect = 4e-11
Identities = 64/305 (20%), Positives = 139/305 (45%), Gaps = 24/305 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDK 59
++IKK ++ML+ +A E E ++ AE LE L +K+ +E+ +
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR 366
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D+ K + + ++ ++S+ R ++ +EEE+ + A + ++ EE K
Sbjct: 367 RFENAPDSA-KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQ 425
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY----EEVARK---LVII 172
+ K ++++ ++ +E++ +E Q +E K A + +E++RK L+ +
Sbjct: 426 MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLAL 485
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAED----KYSQKEDRYEEEIKVL 228
++ LE + S+ + L+E L +Q L D + +KE ++ K +
Sbjct: 486 QTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI 545
Query: 229 SDKLKEAETRA----------EFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
D +E T+A + ER V L+K I++L+E++ +++ S+ + +
Sbjct: 546 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 605
Query: 279 LELNN 283
+ N
Sbjct: 606 ADTTN 610
Score = 65.5 bits (158), Expect = 5e-11
Identities = 62/282 (21%), Positives = 133/282 (47%), Gaps = 22/282 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 705 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVARKLVIIESDLERA 179
+ ++ +K ++++E E L+E+ I + + EE AR ++ E+
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESAR------TNAEKQ 873
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKY-----SQKEDRYEEEIKVLSDKLKE 234
E ++ +V+Q E ++ + + +A ++ + +++ EE +++ + L
Sbjct: 874 VEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLA 933
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
A + + A ++ +L S +E+VA K E + Q L Q
Sbjct: 934 AISEKD-ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 974
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/273 (20%), Positives = 121/273 (44%), Gaps = 26/273 (9%)
Query: 4 IKKKMQMLKL-------DKENALDRAEQAEADKKAAEDRSKQLEDELVS-------LQKK 49
+++++QMLK ++E + + E + K +++ +QL++EL S L+KK
Sbjct: 401 LEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKK 460
Query: 50 LKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
G + E+ + + L +L + K + + I++++E L ++R A
Sbjct: 461 AAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+++ +E E + + Q E+ Q ++ + K + + +RK + +K+
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKI 580
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
++ L E++ + +V+ L+ D L L E+ ++KE E
Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL---EEALAEKERTIE------- 630
Query: 230 DKLKEAETRAE-FAERSVTKLEKSIDDLEEKVA 261
+LKE R E + + +K + DL+EKV+
Sbjct: 631 -RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 662
Score = 50.8 bits (120), Expect = 1e-06
Identities = 54/230 (23%), Positives = 113/230 (49%), Gaps = 41/230 (17%)
Query: 6 KKMQMLK----LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
KK+ LK ++K+ + E+A + D S+QL+D SL+KK +D +++
Sbjct: 791 KKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKK----DDRIEELE 843
Query: 62 EALKD-----AQEKLELAEKKA--TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
EAL++ A+ ++ LA++++ T+AE V L ++ V++EL+ + +L++ Q L
Sbjct: 844 EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA 903
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E E + RA++ + E+ +++K+ +A +++ + L+ + S
Sbjct: 904 EKE---------THLTNLRAERRKHLEEV--LEMKQEALLAAISEK---DANIALLELSS 949
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
++ +E + + +L +QL+ Q LMA D YE++
Sbjct: 950 SKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA---------DNYEDD 990
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 76.6 bits (187), Expect = 2e-14
Identities = 76/312 (24%), Positives = 141/312 (45%), Gaps = 42/312 (13%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 619
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 680 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ-LEEQLRIMDQTLKALM 208
E ++ D D+K E+ R++ + + + ++ + + Q LEE R D +
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 798
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLK---EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
+D +K+DR EE + L + ++ E E E + T EK +++L + K+
Sbjct: 799 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 858
Query: 266 ENLSMHQMLDQT 277
E SM L T
Sbjct: 859 ELESMKAKLSST 870
Score = 67.0 bits (162), Expect = 2e-11
Identities = 61/295 (20%), Positives = 130/295 (44%), Gaps = 18/295 (6%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 558
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 559 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 618
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
D ++ +K ++ + + + +E L + K A + +L +E LE+
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 678
Query: 180 EERAELSEGQVRQLEE---QLRI---MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+E E Q+++ E + R M ++ L +Y + + + E+ L + LK
Sbjct: 679 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 234 EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE----ENLSMHQMLDQTLLELNNM 284
E E ++ + +LE+ + D +KVA+ K E QML++ +N+
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNL 793
Score = 65.5 bits (158), Expect = 5e-11
Identities = 62/282 (21%), Positives = 133/282 (47%), Gaps = 22/282 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 677 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 791
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVARKLVIIESDLERA 179
+ ++ +K ++++E E L+E+ I + + EE AR ++ E+
Sbjct: 792 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESAR------TNAEKQ 845
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKY-----SQKEDRYEEEIKVLSDKLKE 234
E ++ +V+Q E ++ + + +A ++ + +++ EE +++ + L
Sbjct: 846 VEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLA 905
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
A + + A ++ +L S +E+VA K E + Q L Q
Sbjct: 906 AISEKD-ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 946
Score = 58.2 bits (139), Expect = 8e-09
Identities = 53/284 (18%), Positives = 128/284 (45%), Gaps = 10/284 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDK 59
++IKK ++ML+ +A E E ++ AE LE L +K+ +E+ +
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR 366
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D+ K + + ++ ++S+ R ++ +EEE+ + A + ++ EE K
Sbjct: 367 RFENAPDSA-KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQ 425
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+ K ++++ + ++++ ++ +L + E ++ + + + +++ L
Sbjct: 426 MEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAK 485
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRA 239
E+RA + + +V L +L + L ++++ EI L D L
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML------- 538
Query: 240 EFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ ER V L+K I++L+E++ +++ S+ + + + N
Sbjct: 539 DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 582
Score = 51.6 bits (122), Expect = 8e-07
Identities = 53/285 (18%), Positives = 122/285 (42%), Gaps = 32/285 (11%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD--KYSE 62
+K+ ML+ + + A + A KA + + + ++ S+++ L+ E+E+ K +
Sbjct: 354 EKENSMLREEMHRRFENAPDS-AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
AL + + E+ + + + + + +I V++EL R L KLE +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKF--MKNKIGQVKQELSRKDTELLALQTKLETLTNQFSD 470
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQL---------------KEAKHIAEDADRKYEEVAR 167
S++ ++V++ E++ I + ++ K+ K I + A+ K + A
Sbjct: 471 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQ-AG 529
Query: 168 KLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV 227
++ ++ L+ E + + + ++ L+EQLR ++ + +L + +
Sbjct: 530 EIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT 589
Query: 228 LSDKLKEAETRAE-----------FAERSVTKLEKSIDDLEEKVA 261
L + L E E E + + +K + DL+EKV+
Sbjct: 590 LEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 634
Score = 50.8 bits (120), Expect = 1e-06
Identities = 54/230 (23%), Positives = 113/230 (49%), Gaps = 41/230 (17%)
Query: 6 KKMQMLK----LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
KK+ LK ++K+ + E+A + D S+QL+D SL+KK +D +++
Sbjct: 763 KKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKK----DDRIEELE 815
Query: 62 EALKD-----AQEKLELAEKKA--TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
EAL++ A+ ++ LA++++ T+AE V L ++ V++EL+ + +L++ Q L
Sbjct: 816 EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA 875
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E E + RA++ + E+ +++K+ +A +++ + L+ + S
Sbjct: 876 EKE---------THLTNLRAERRKHLEEV--LEMKQEALLAAISEK---DANIALLELSS 921
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
++ +E + + +L +QL+ Q LMA D YE++
Sbjct: 922 SKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA---------DNYEDD 962
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.122 0.293
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,269,348
Number of Sequences: 37866
Number of extensions: 383927
Number of successful extensions: 15447
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 746
Number of HSP's successfully gapped in prelim test: 1027
Number of HSP's that attempted gapping in prelim test: 3194
Number of HSP's gapped (non-prelim): 6382
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.