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Search of human proteins with 63252898
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 532 e-151
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 500 e-142
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 495 e-140
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 486 e-138
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 471 e-133
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 456 e-128
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 442 e-124
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 434 e-122
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 416 e-116
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 404 e-113
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 358 2e-99
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 331 4e-91
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 327 7e-90
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 321 5e-88
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 310 9e-85
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 306 2e-83
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 243 1e-64
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 84 2e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 84 2e-16
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 82 7e-16
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 80 2e-15
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 80 2e-15
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 79 5e-15
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 79 6e-15
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 79 6e-15
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 79 6e-15
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 79 6e-15
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 77 2e-14
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 76 3e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 76 4e-14
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 532 bits (1370), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 500 bits (1288), Expect = e-142
Identities = 267/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTS+
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 495 bits (1275), Expect = e-140
Identities = 259/284 (91%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSV KLEK+IDDLEDELYAQKLKYKAISEELDHALNDMTSI
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 486 bits (1251), Expect = e-138
Identities = 261/284 (91%), Positives = 272/284 (95%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 471 bits (1213), Expect = e-133
Identities = 243/284 (85%), Positives = 271/284 (95%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E KC +LEEELK VTNNLKSLEAQA+KYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSV KLEK+IDDLEDE+YAQK+KYKAISEELD+ALND+TS+
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 456 bits (1172), Expect = e-128
Identities = 245/284 (86%), Positives = 263/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 442 bits (1136), Expect = e-124
Identities = 231/284 (81%), Positives = 258/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAER+V KLEK+IDDLE++L K + + + LD LN++ I
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 434 bits (1116), Expect = e-122
Identities = 234/284 (82%), Positives = 256/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 416 bits (1068), Expect = e-116
Identities = 218/284 (76%), Positives = 252/284 (88%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 404 bits (1037), Expect = e-113
Identities = 218/284 (76%), Positives = 247/284 (86%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 358 bits (920), Expect = 2e-99
Identities = 193/238 (81%), Positives = 210/238 (88%)
Query: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED+LY Q + + ++ EL ALN+
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 331 bits (849), Expect = 4e-91
Identities = 174/237 (73%), Positives = 203/237 (85%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 47.4 bits (111), Expect = 1e-05
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA---ISEELDHALN 279
E + KL+EAE A+ +ER + +E E+++ Q+++ K I+EE D
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 280 DM 281
++
Sbjct: 128 EV 129
Score = 29.6 bits (65), Expect = 3.1
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 197 LKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA-EFAERSVTKLEKSIDD 255
++ V ++ L+ QA+ ++ +R + E+ E E RA E AE V L + I
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV--------EGERRAREQAEAEVASLNRRIQL 58
Query: 256 LEDELYAQKLKYKAISEELDHA 277
+E+EL + + ++L+ A
Sbjct: 59 VEEELDRAQERLATALQKLEEA 80
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 327 bits (838), Expect = 7e-90
Identities = 173/240 (72%), Positives = 200/240 (83%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L K ++ LD L D+ +
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 55.1 bits (131), Expect = 7e-08
Identities = 33/114 (28%), Positives = 61/114 (53%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ E+ K + + L SL+ + + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Score = 47.4 bits (111), Expect = 1e-05
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA---ISEELDHALN 279
E + KL+EAE A+ +ER + +E E+++ Q+++ K I+EE D
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 280 DM 281
++
Sbjct: 128 EV 129
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/138 (24%), Positives = 64/138 (46%), Gaps = 14/138 (10%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESKC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ +E+L+ EA +++ EEE+ + KL+EAE A+ +E
Sbjct: 155 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTD-------KLKEAETRAEFAE 207
Query: 125 RGMKVIESRAQKDEEKME 142
R + +E E+K++
Sbjct: 208 RSVAKLEKTIDDLEDKLK 225
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 321 bits (822), Expect = 5e-88
Identities = 167/244 (68%), Positives = 204/244 (83%)
Query: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
KYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+
Sbjct: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L K + + + LD LN+
Sbjct: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
Query: 281 MTSI 284
+ I
Sbjct: 245 LNCI 248
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 310 bits (794), Expect = 9e-85
Identities = 161/237 (67%), Positives = 196/237 (82%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 47.4 bits (111), Expect = 1e-05
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA---ISEELDHALN 279
E + KL+EAE A+ +ER + +E E+++ Q+++ K I+EE D
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 280 DM 281
++
Sbjct: 128 EV 129
Score = 29.6 bits (65), Expect = 3.1
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 197 LKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA-EFAERSVTKLEKSIDD 255
++ V ++ L+ QA+ ++ +R + E+ E E RA E AE V L + I
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV--------EGERRAREQAEAEVASLNRRIQL 58
Query: 256 LEDELYAQKLKYKAISEELDHA 277
+E+EL + + ++L+ A
Sbjct: 59 VEEELDRAQERLATALQKLEEA 80
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 306 bits (783), Expect = 2e-83
Identities = 160/240 (66%), Positives = 193/240 (80%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L K ++ LD L D+ +
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/114 (26%), Positives = 60/114 (52%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ + +++ + ++ L L + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Score = 47.4 bits (111), Expect = 1e-05
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA---ISEELDHALN 279
E + KL+EAE A+ +ER + +E E+++ Q+++ K I+EE D
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 280 DM 281
++
Sbjct: 128 EV 129
Score = 37.7 bits (86), Expect = 0.012
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 14/138 (10%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESRC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++ E++ L ++ A +++ EEE+ + KL+EAE A+ +E
Sbjct: 155 REMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD-------KLKEAETRAEFAE 207
Query: 125 RGMKVIESRAQKDEEKME 142
R + +E E+K++
Sbjct: 208 RSVAKLEKTIDDLEDKLK 225
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 243 bits (620), Expect = 1e-64
Identities = 133/230 (57%), Positives = 172/230 (74%), Gaps = 7/230 (3%)
Query: 62 EALKDAQEKLELAEKKATD----AEADVASLNRRIQLVEEELDRAQERLATA---LQKLE 114
+A+K + L+L ++ A D AEAD R + +EEE Q++L ++K
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E
Sbjct: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKE
Sbjct: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 181
Query: 235 AETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
AETRAEFAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 182 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 14/121 (11%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLK---GTEDEL- 57
+ + +K+ +L+ + E + +RAE AE R++QLE+EL ++ + LK +E+E
Sbjct: 110 EEVARKLVILEGELERSEERAE-------VAESRARQLEEELRTMDQALKSLMASEEEYS 162
Query: 58 ---DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
DKY E +K +EKL+ AE +A AE VA L + I +EE L A+E Q L+
Sbjct: 163 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLD 222
Query: 115 E 115
+
Sbjct: 223 Q 223
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 83.6 bits (205), Expect = 2e-16
Identities = 64/277 (23%), Positives = 129/277 (46%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
+++ + +E L +A++ E K+ E QL++EL + ++ + + E D+ ++ +
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
++ K LA ++ EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD----RKYEE----VARKLVIIESDLE 177
+ + S AQK+E + E Q KE K ++ + KY+ + K+ +E L+
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 178 RAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
+ + + + E++LK V + AE+Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
A+ A S KL++ ++D + A + ++ +L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 72.4 bits (176), Expect = 4e-13
Identities = 62/284 (21%), Positives = 127/284 (44%), Gaps = 31/284 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEA-----------DKKAAEDRSKQLEDELVSLQKKL 50
++ ++K+Q+ K+ E L + E+ + +KK EDR + L ++K
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 51 KGTEDELDKYSEALKDAQEKLELAEKK--------------ATDAEADVASLNRRIQLVE 96
K +K+ + D +E+L EK+ +TD +A L +I ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+L + +E L AL ++EE + + + ++ +ES+ + +E +E + +A+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 216
D + E + +L E L+ + EL + E+ KT+ K+ EAQ ++ Q
Sbjct: 1136 DLGEELEALKTEL---EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
K + EE+ ++ K + E A+++ LE +L +E+
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQT---LENERGELANEV 1233
Score = 68.9 bits (167), Expect = 5e-12
Identities = 58/270 (21%), Positives = 122/270 (45%), Gaps = 10/270 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
KK++ L+ + E A + AE + + L +EL +L+ +L+ T D E
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 66 DAQEKLELAEK----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++++ + +K +A EA + + ++ EEL E+ LE+A++
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL- 1222
Query: 122 ESERG-----MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
E+ERG +KV+ E K + E QL+E + + +R E+A K+ ++ +L
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 177 ERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
+ S+ K ++L ++ + + L+ + ++ ++++ ++K + D+
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 237 TRAEFAERSVTKLEKSIDDLEDELYAQKLK 266
+ E E + LEK I L ++ K K
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Score = 68.2 bits (165), Expect = 8e-12
Identities = 65/289 (22%), Positives = 138/289 (47%), Gaps = 27/289 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL----QKKLKGTEDELDK 59
++K + L+ E + E+ E + +A ED +LE L ++ ++ L+G +++ ++
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 60 YSEAL-----------KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
+ L +D +++ +A E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKYEEV 165
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R+ ++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 166 ARKLV--IIESDLERA---EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+L I S + A EE+ L E + A+LEEEL+ N + + + +K + + D+
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRL-EARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA 269
++ + ++ E + ER +L+ + ++E + K KYKA
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV---KSKYKA 1807
Score = 65.1 bits (157), Expect = 7e-11
Identities = 62/253 (24%), Positives = 119/253 (47%), Gaps = 28/253 (11%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERL 106
++++ E+EL K E A+ +L E + A+ L ++Q E A+E
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 107 ATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE-- 164
A K +E E+ + +E+R +++EE+ + + + K+ + ++ + + EE
Sbjct: 904 ARLTAKKQELEEICHD-------LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 165 -VARKL----VIIESDLERAEERAELSEGKCAELEEELKTV-------TNNLKSLEAQAE 212
+KL V E+ L++ EE + E + +L +E K + T NL E +++
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
Query: 213 KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED---ELYAQ----KL 265
++ ++++E I L ++L+ E + + E++ KLE DL D EL AQ K+
Sbjct: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
Query: 266 KYKAISEELDHAL 278
+ EEL AL
Sbjct: 1077 QLAKKEEELQAAL 1089
Score = 62.8 bits (151), Expect = 3e-10
Identities = 60/263 (22%), Positives = 116/263 (44%), Gaps = 22/263 (8%)
Query: 12 KLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
KL K+ +AL+ Q + E+R K +SL KLK EDE + + E L++ +E
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQK------LSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 71 LELAEKKATDAEADVASLNRR-------IQLVEEELDRAQERLATALQKLEEAEKAADES 123
EK+ A VA + ++ ++ EE + Q+ L Q+ EE A D+
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES----DLERA 179
E+ ++R Q++ + + + +++ E +K++++ + I + + +RA
Sbjct: 1412 EK----TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA 1467
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA 239
E A E K L L+ LE +++ + + + + E E
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 240 EFAERSVTKLEKSIDDLEDELYA 262
E+ V +++ +++LEDEL A
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQA 1550
Score = 62.0 bits (149), Expect = 6e-10
Identities = 59/277 (21%), Positives = 131/277 (47%), Gaps = 27/277 (9%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAE---DRSKQLEDELVS----LQKKLKGTEDELDK 59
K++ +L EN L E ++ A + Q E EL + L+ +L + EL+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE- 914
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D + ++E E++ +A+ + + IQ +EE+L+ + +A QKL + EK
Sbjct: 915 --EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKL-QLEKV 967
Query: 120 ADES-----ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR------- 167
E+ E ++E + K ++ ++ E ++ E + + K + +A+
Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEA 1027
Query: 168 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
+ +E L R E++ + E +LE + +++ + L+AQ + + + EEE++
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
+++E + A + + +LE I +L+++L +++
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 62.0 bits (149), Expect = 6e-10
Identities = 68/298 (22%), Positives = 135/298 (45%), Gaps = 23/298 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDE-LDKYSEA 63
+++ Q L+ +K+ ++ E + E ++L+ E V+ + KLK E+E + +
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 64 LKDAQEKLELAEKKA------TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K A+EK L ++ A T+ E SL + E + +ERL ++ +E E
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE 1047
Query: 118 KA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----RKYE 163
K D ++ ++ E +AQ E KM++ +E+Q A+ E A +K
Sbjct: 1048 KTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIR 1107
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
E+ ++ ++ DLE +E + +L EEL+ + L+ + + E+
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 224 EIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
E+ +L L +EA+T + K +++++L ++L Q + KA E+ L +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL-EQTKRVKANLEKAKQTLEN 1224
Score = 61.2 bits (147), Expect = 1e-09
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 44/314 (14%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
++ K++ ++ +K + ++ E+ E K E + L ++ ++KK++ + L+ E
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA------QERLATALQKLEEA 116
+ Q+ LE ++ + A L + +++ELD Q + A L+K ++
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 117 --EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE----------- 163
+ A+E K E R + + E E + L A+ + E ++K E
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 164 ---------EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSL 207
+V + + +E E++ E + + ELE+EL+ + NL+++
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAM 1565
Query: 208 EAQAEKYSQKEDRYEEEIK---VLSDKLKEAETRAEFAERSVT-----KLEKSIDDLEDE 259
+AQ E+ Q D EE K V + EAE E +RS+ KLE + DLE
Sbjct: 1566 KAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAH 1625
Query: 260 L-YAQKLKYKAISE 272
+ A K + +AI +
Sbjct: 1626 IDSANKNRDEAIKQ 1639
Score = 59.7 bits (143), Expect = 3e-09
Identities = 61/307 (19%), Positives = 138/307 (44%), Gaps = 29/307 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
++ K ++Q D LD Q+ + + + + QL E ++ K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + L A ++A + +A++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IESRAQKDEEKMEIQEIQLKEAK----HIAEDADRKYEEVARKLV-- 170
++ MK +E Q E+ E+ L+ K + D + EE ++LV
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 171 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 230
+ E + E +ER + S A + E+ +LK LEA + ++ D ++++ L
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEM-----DLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 231 KLKEA-----ETR---------AEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
++K+ +TR A+ E+ + +E + L++EL A + + +E D
Sbjct: 1646 QMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDE 1705
Query: 277 ALNDMTS 283
+++ +
Sbjct: 1706 LADEIAN 1712
Score = 59.7 bits (143), Expect = 3e-09
Identities = 60/291 (20%), Positives = 144/291 (49%), Gaps = 37/291 (12%)
Query: 2 DAIKKKMQMLKLDK------ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED 55
+A+++K ++ +L+K E+ + + E + LE ++ ++ +L+ ED
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
EL +A +DA+ +LE+ + +A A R +Q +E+ + +++L ++++E
Sbjct: 1547 EL----QATEDAKLRLEV------NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME- 1595
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
AE + +R M V A + + +M++++++ HI + A++ +E ++L +++
Sbjct: 1596 AELEDERKQRSMAV----AARKKLEMDLKDLEA----HI-DSANKNRDEAIKQLRKLQAQ 1646
Query: 176 LE---------RAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIK 226
++ RA L++ K E E++LK++ + L+ + + + + ++E
Sbjct: 1647 MKDCMRELDDTRASREEILAQAK--ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 227 VLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
L+D++ + + A +LE I LE+EL ++ + I++ L A
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Score = 52.4 bits (124), Expect = 5e-07
Identities = 60/305 (19%), Positives = 127/305 (41%), Gaps = 34/305 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
K+ Q + + K+ + A+ EA + + Q +EL ++ K + L+K + L+
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATAL-QKLEEAEKAAD 121
+ + +L K + D ++++ +EL ER+ T L K+ + + D
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ +S++ K + E QL++ + + ++ +R+ ++ KL +E + E
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQ----------AEKYSQK--------EDRYEE 223
+ E E LE+++ T+ + ++ + AE+ +K R+EE
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 224 EIKVLSDKLKEAETRAE-----------FAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
++ DKL++ +TR + +S LEK + L +K +E
Sbjct: 1404 KVAAY-DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE 1462
Query: 273 ELDHA 277
E D A
Sbjct: 1463 ERDRA 1467
Score = 42.4 bits (98), Expect = 5e-04
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 21/187 (11%)
Query: 96 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 155
EEE+ +E L K+ E + AA+ M+ ++S+ EK+++QE QL+ +
Sbjct: 844 EEEMMAKEEELV----KVREKQLAAENRLTEMETLQSQLMA--EKLQLQE-QLQAETELC 896
Query: 156 EDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYS 215
+A EE+ +L + +LE C +LE ++ + L+A+ +K
Sbjct: 897 AEA----EELRARLTAKKQELEEI----------CHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 216 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
Q EE+++ ++ + E + KLE+ LED+ + K + + +
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 276 HALNDMT 282
++T
Sbjct: 1003 EFTTNLT 1009
Score = 42.0 bits (97), Expect = 6e-04
Identities = 33/175 (18%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-DKYSEALK 65
K L++D+ N E++ A K E+ +QLE + L+ KL+ E + KY ++
Sbjct: 1753 KKANLQIDQINTDLNLERSHAQKN--ENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ K+ E++ + + + ++++ E++L ++ + E+ + AD++
Sbjct: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+K ++ + ++ EE+ + ++ + EDA + + R++ +++ L R +
Sbjct: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 29.6 bits (65), Expect = 3.1
Identities = 25/118 (21%), Positives = 48/118 (40%), Gaps = 10/118 (8%)
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ R EE E + ++ E+ N L +E + ++ + +E+++ ++ EA
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 236 ETRAEFAERSVTKLEKSIDDLE----------DELYAQKLKYKAISEELDHALNDMTS 283
E +LE+ DLE L A+K K + +EL+ L + S
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES 957
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 83.6 bits (205), Expect = 2e-16
Identities = 59/279 (21%), Positives = 132/279 (47%), Gaps = 9/279 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE---- 117
E +++ +EK+ E+K E ++ + ++ EEE + QE + +K+ E E
Sbjct: 484 EKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 118 --KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
+ E E ++ E + + EEKM QE +++E + + K E K+ E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ EE + E K E EE++ ++ E + + +K E++I+ +K++E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660
Query: 236 ETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + E + + E+ + + E+++ Q+ K + E++
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/249 (20%), Positives = 121/249 (48%), Gaps = 17/249 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED------ 55
+ I+++ + ++ +E + E+ +K E+ +Q ++E+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E ++ +EK+ E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E E M E + + EEKM+ QE +++ + + ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV--LSDKLK 233
++ EE+ E K E EE+++ E + + Q+E +E+E+++ +K++
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQ---------EQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Query: 234 EAETRAEFA 242
E + E A
Sbjct: 715 EHQEHLEAA 723
Score = 69.3 bits (168), Expect = 4e-12
Identities = 63/247 (25%), Positives = 123/247 (49%), Gaps = 35/247 (14%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD + S
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE + E E+ R+ EE+ + E + R EE E K ELEE++
Sbjct: 398 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMH-- 448
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
+ EK ++E++ +EE K+ +K +E E + E + + E+ I + E++
Sbjct: 449 ---------EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 260 LYAQKLK 266
++ Q+ K
Sbjct: 500 MWRQEEK 506
Score = 69.3 bits (168), Expect = 4e-12
Identities = 58/281 (20%), Positives = 134/281 (47%), Gaps = 13/281 (4%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ ++ E + Q++E+ E ++ Q +EAK + + K E K+ E + R EE
Sbjct: 449 EQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKIREQEEKMWRQEE 505
Query: 182 RA-ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV---------LSDK 231
+ E + + E +E + + + + Q E + QKE +E+E K+ +K
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ + E + E V + E+ I + E+++ Q+ K + E
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Score = 68.2 bits (165), Expect = 8e-12
Identities = 58/275 (21%), Positives = 126/275 (45%), Gaps = 24/275 (8%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS----EALKDAQE 69
+K ++ ++ EA E++ ++ E+++ ++K+ E+++ + E + QE
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 70 KLELAEKKATDAEA------DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ E+K + E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E ++ E + ++ EEK+ QE +E + + + K E K+ E + R EE+
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E K E EE+++ E + Q+E +E+E +K+ E E + + E
Sbjct: 644 REQEKKIREQEEKIR---------EQEEMMQEQEEKMWEQE-----EKMCEQEEKMQEQE 689
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEELDHAL 278
+ + E+ + + E L Q+ K + E L+ A+
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 67.0 bits (162), Expect = 2e-11
Identities = 64/276 (23%), Positives = 127/276 (46%), Gaps = 12/276 (4%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL----VIIESDLER 178
E M E + ++ EE M +E +++ + + + + K E+ K+ I E + +R
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 179 AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE + K E E ++ ++ E + + +K R EE+I +K++E E R
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-QEKIREEEKR 519
Query: 239 AEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + + + E+ I + ++E++ QK K E++
Sbjct: 520 QE--QEEMWRQEEKIRE-QEEIWRQKEKIHEQEEKI 552
Score = 63.9 bits (154), Expect = 2e-10
Identities = 57/274 (20%), Positives = 123/274 (44%), Gaps = 28/274 (10%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
++E + R E+ +K E++ ++ E+ + ++K++ E+ + + E +++ +EK+
Sbjct: 393 EQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER-------- 125
EK E R Q +E + R ++ E+ EK ++ E+
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEEKMWRQEEKI 507
Query: 126 --GMKVIESRAQKDEEKMEIQEIQLKEAK---------HIAEDADRKYEE----VARKLV 170
K+ E ++++E+M QE +++E + H E+ RK EE K+
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 171 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 230
E + EE+ E K E EE+++ ++ E ++ +K EE++ +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 231 KLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
K++E E + E + + EK I + E+++ Q+
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Score = 30.8 bits (68), Expect = 1.4
Identities = 37/188 (19%), Positives = 79/188 (42%), Gaps = 44/188 (23%)
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+ +L ++ K A E E+ + + ++ +K ADR EE+ ++
Sbjct: 225 ISRLHDSWKFAGELEQALSAVATQKKK---------------------ADRYIEELTKER 263
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSLEAQAEK--------- 213
+ +L R E + K A+L+E+L+ V + N+K L+ + E+
Sbjct: 264 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ 323
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEF-------AERSVTKLEKSIDDLEDELYAQKLK 266
+ D +E++ +S KL+ E E + + E+ I + E+++ Q+ K
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 267 YKAISEEL 274
+ E++
Sbjct: 384 IREQEEKI 391
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 81.6 bits (200), Expect = 7e-16
Identities = 60/288 (20%), Positives = 135/288 (46%), Gaps = 17/288 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEDELVSLQKKLKGTEDELDK 59
+ ++ K+Q ++++ +R Q + +K E++ ++ E+++ ++K++ E+++ +
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + +EK+ E+ + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 AD-------------ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA 166
+ E E ++ E Q+ EEKM QE ++ E + ++ + K
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 167 RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIK 226
K+ E + EE+ E E EE++ + EA+ ++ +K R EE+I+
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 227 VLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
K++E E + E + + E+ + + E+++ Q+ K + E++
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Score = 81.6 bits (200), Expect = 7e-16
Identities = 51/239 (21%), Positives = 113/239 (47%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K K+ E + EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E E EE++ + E + ++ +K R EE+++ +L++ E + +
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 79.3 bits (194), Expect = 3e-15
Identities = 64/282 (22%), Positives = 133/282 (47%), Gaps = 20/282 (7%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 271
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+E + ++ + +EK+ E+K + E + +I+ EE++ R +E + +K
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E+ E E ++ +E + ++EK+ QE + +E + I E R+ +E K+
Sbjct: 332 MRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQ 388
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
E + EE+ E E EE++ + E + ++ +K R EE+I+ K+
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+E E + E + + E+ + + E ++ Q+ K + E++
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490
Score = 79.3 bits (194), Expect = 3e-15
Identities = 49/253 (19%), Positives = 125/253 (49%), Gaps = 4/253 (1%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL----ELAE 75
++ ++ E + E++ ++ E+ + ++K++ E+ + + E +++ +EK+ ++ E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
++ E + + Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 136 KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEE 195
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EGK E E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 196 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
+++ ++ E + + +K EE+I+ + ++E E + E + + E+ + +
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 256 LEDELYAQKLKYK 268
E+++ Q+ K +
Sbjct: 542 QEEKMRRQEEKMR 554
Score = 79.3 bits (194), Expect = 3e-15
Identities = 56/257 (21%), Positives = 132/257 (51%), Gaps = 10/257 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++LE+++ Q+K++ E++ + E ++
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHE-QEKIREQEEKRQE-EEKIR 373
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ QEK + E K E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 374 E-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E+ ++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL--SDKLKEAETRAEFAE 243
E K E E++++ ++ E ++ Q+E +E+E K+ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550
Query: 244 RSVTKLEKSIDDLEDEL 260
+ + E + E+++
Sbjct: 551 EKMREQEVRLRQQEEKM 567
Score = 70.1 bits (170), Expect = 2e-12
Identities = 66/264 (25%), Positives = 123/264 (46%), Gaps = 34/264 (12%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-------- 84
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 85 -VASL----------NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
A L NR Q EE++ R +E++ +K++E E+ E E M+ E
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 134 AQKDEEKMEIQE---------IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ EEKM QE I+ E K ++ R+ EE ++ I +R E+ A+
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 185 L--SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 242
+ E K E EE+++ ++ E + + +K EEE++ +K++ E +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 243 ERSVTKLEKSIDDLEDELYAQKLK 266
E+ + + E+ I + E+ + Q+ K
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEK 468
Score = 67.0 bits (162), Expect = 2e-11
Identities = 39/201 (19%), Positives = 100/201 (49%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
+K ++ ++ EA E++ ++ E+++ ++ ++ E+++ + E + + +E+++
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
E+K E + ++I+ EE++ +E + +K+ E E E E M+ E +
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
++ EEK+ QE +++E + + + +E K+ E + EE+ + E K
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Query: 194 EEELKTVTNNLKSLEAQAEKY 214
EE+++ L+ E + +++
Sbjct: 550 EEKMREQEVRLRQQEEKMQEH 570
Score = 62.0 bits (149), Expect = 6e-10
Identities = 64/279 (22%), Positives = 129/279 (46%), Gaps = 32/279 (11%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAEKAADESERGMKVIESRA-- 134
++ + +V L R +L+RA +L Q+L+ EA+ E + ++++
Sbjct: 225 KSEIQLNVKELKR-------KLERA--KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 135 --------QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Q+ EEKM QE +++E + ++ + K E K+ E + EE+
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 187 EGKCAELEEELKTVTNNLKSLE---------AQAEKYSQKEDRYEEEIKV--LSDKLKEA 235
E E EE+++ + + E + EK ++E R E+E K+ +K++E
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 236 ETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + E + + E+ + + E++++ Q+ + + E++
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Score = 30.8 bits (68), Expect = 1.4
Identities = 37/188 (19%), Positives = 79/188 (42%), Gaps = 44/188 (23%)
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+ +L ++ K A E E+ + + ++ +K ADR EE+ ++
Sbjct: 152 ISRLHDSWKFAGELEQALSAVATQKKK---------------------ADRYIEELTKER 190
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSLEAQAEK--------- 213
+ +L R E + K A+L+E+L+ V + N+K L+ + E+
Sbjct: 191 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ 250
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEF-------AERSVTKLEKSIDDLEDELYAQKLK 266
+ D +E++ +S KL+ E E + + E+ I + E+++ Q+ K
Sbjct: 251 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
Query: 267 YKAISEEL 274
+ E++
Sbjct: 311 IREQEEKM 318
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 80.5 bits (197), Expect = 2e-15
Identities = 72/326 (22%), Positives = 152/326 (46%), Gaps = 49/326 (15%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 647
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 648 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 707
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 708 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK---- 205
E ++ D D+K E+ R++ + + + ++ + K A++ EE + +NL
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 826
Query: 206 ----SLEAQAEKYSQKEDRYEEEIKVLSDK---LKEAETRAEFAERSVTKLEKSIDDLED 258
SL + ++ + E+ E +++ +++ L + E+ AE+ V +L +++ ++
Sbjct: 827 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 886
Query: 259 ELYAQKLKYKAISEELDHALNDMTSI 284
EL + K K + + L +T++
Sbjct: 887 ELESMKAKLSSTQQSLAEKETHLTNL 912
Score = 70.9 bits (172), Expect = 1e-12
Identities = 66/292 (22%), Positives = 137/292 (46%), Gaps = 25/292 (8%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 705 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK--EDRYEEEIKVLSDK- 231
+E+ ++ E + K + ++ L +L +L A+ K+ ++ E + E + +S+K
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 939
Query: 232 ----LKEAETRAEFAERSVTKLEKSIDDLEDELYAQ---KLKYKAISEELDH 276
L E + + + V L++ D L +L Q ++K A + E DH
Sbjct: 940 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 991
Score = 62.4 bits (150), Expect = 4e-10
Identities = 59/286 (20%), Positives = 127/286 (44%), Gaps = 38/286 (13%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 586
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Query: 120 ADESERGMKVIESRA---QKDEEKMEIQEIQLKE-AKHIAEDADRKYEEVARKLVIIESD 175
D ++ +K ++ + Q D + E + LKE A +A +K +S
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKK-----------DSR 695
Query: 176 LERAEERAELSEGKCAELEEELK-------------TVTNNLKSLEAQAEKYSQKEDRYE 222
L+ E E + +C ++E +LK +++ ++ LE + +Y + + +
Sbjct: 696 LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 755
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
E+ L + LKE E ++ + +LE+ + D ++ LK+K
Sbjct: 756 AEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKV--ANLKHK 799
Score = 56.6 bits (135), Expect = 2e-08
Identities = 48/281 (17%), Positives = 126/281 (44%), Gaps = 24/281 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++++QMLK AL E+ E K+ RS K ++++++ E
Sbjct: 401 LEEEIQMLK--SNGALSTEEREEEMKQMEVYRSHS------------KFMKNKVEQLKEE 446
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L + + E +KKA +A++ + + + + EL Q +L T + ++++ +
Sbjct: 447 LSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVL 506
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
+ + E RA + +++ ++L+E + + ++ +++A + ++ ++
Sbjct: 507 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML 566
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
++ E K L+++++ + L+ E Q +E +K L +T E
Sbjct: 567 DVKERKVNVLQKKIENLQEQLRDKEKQMSS-------LKERVKSLQADTTNTDTALTTLE 619
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
++ + E++I+ L+++ + + EE+D+ D+ +
Sbjct: 620 EALAEKERTIERLKEQ---RDRDEREKQEEIDNYKKDLKDL 657
Score = 45.1 bits (105), Expect = 7e-05
Identities = 55/275 (20%), Positives = 118/275 (42%), Gaps = 30/275 (10%)
Query: 19 LDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 78
L++ Q ++ + E +L +E ++L + K L+ E++EL
Sbjct: 242 LNQLFQQDSSSRTGEPCVAELTEENF---QRLHAEHERQAKELFLLRKTLEEMELR---- 294
Query: 79 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV--IESRAQK 136
E +LN R + +++ L+ Q + +A E+ E+ +E M V +ES ++
Sbjct: 295 --IETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQ 352
Query: 137 DEEKMEIQEIQLKEAKHIAEDADRKYEEV--ARKLVIIESDLERAEERAELSEGKCAELE 194
E KE + E+ R++E + K +++ +E + + E +LE
Sbjct: 353 KE----------KENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLE 402
Query: 195 EELKTV-TNNLKSLEAQAEKYSQKE------DRYEEEIKVLSDKLKEAETRAEFAERSVT 247
EE++ + +N S E + E+ Q E + +++ L ++L E + E ++
Sbjct: 403 EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAA 462
Query: 248 KLEKSIDDLEDELYAQKLKYKAISEELDHALNDMT 282
L+ I ++ EL + + A+ +L+ N +
Sbjct: 463 GLQAEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 80.5 bits (197), Expect = 2e-15
Identities = 72/326 (22%), Positives = 152/326 (46%), Gaps = 49/326 (15%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 619
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 680 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK---- 205
E ++ D D+K E+ R++ + + + ++ + K A++ EE + +NL
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 798
Query: 206 ----SLEAQAEKYSQKEDRYEEEIKVLSDK---LKEAETRAEFAERSVTKLEKSIDDLED 258
SL + ++ + E+ E +++ +++ L + E+ AE+ V +L +++ ++
Sbjct: 799 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 858
Query: 259 ELYAQKLKYKAISEELDHALNDMTSI 284
EL + K K + + L +T++
Sbjct: 859 ELESMKAKLSSTQQSLAEKETHLTNL 884
Score = 70.9 bits (172), Expect = 1e-12
Identities = 66/292 (22%), Positives = 137/292 (46%), Gaps = 25/292 (8%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 677 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 791
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 792 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 851
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK--EDRYEEEIKVLSDK- 231
+E+ ++ E + K + ++ L +L +L A+ K+ ++ E + E + +S+K
Sbjct: 852 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 911
Query: 232 ----LKEAETRAEFAERSVTKLEKSIDDLEDELYAQ---KLKYKAISEELDH 276
L E + + + V L++ D L +L Q ++K A + E DH
Sbjct: 912 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 963
Score = 62.4 bits (150), Expect = 4e-10
Identities = 59/286 (20%), Positives = 127/286 (44%), Gaps = 38/286 (13%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 558
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 559 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 618
Query: 120 ADESERGMKVIESRA---QKDEEKMEIQEIQLKE-AKHIAEDADRKYEEVARKLVIIESD 175
D ++ +K ++ + Q D + E + LKE A +A +K +S
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKK-----------DSR 667
Query: 176 LERAEERAELSEGKCAELEEELK-------------TVTNNLKSLEAQAEKYSQKEDRYE 222
L+ E E + +C ++E +LK +++ ++ LE + +Y + + +
Sbjct: 668 LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 727
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
E+ L + LKE E ++ + +LE+ + D ++ LK+K
Sbjct: 728 AEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKV--ANLKHK 771
Score = 52.0 bits (123), Expect = 6e-07
Identities = 49/279 (17%), Positives = 124/279 (44%), Gaps = 12/279 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD--KYSE 62
+K+ ML+ + + A + A KA + + + ++ S+++ L+ E+E+ K +
Sbjct: 354 EKENSMLREEMHRRFENAPDS-AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
AL + + E+ + + + + + +I V++EL R L KLE +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKF--MKNKIGQVKQELSRKDTELLALQTKLETLTNQFSD 470
Query: 123 SERGMKVI-------ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
S++ ++V+ E RA + +++ ++L+E + + ++ +++A + +
Sbjct: 471 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGE 530
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ ++ ++ E K L+++++ + L+ E Q ++ + + L
Sbjct: 531 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL 590
Query: 236 ETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E ER++ +L++ D E E + YK ++L
Sbjct: 591 EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL 629
Score = 42.7 bits (99), Expect = 4e-04
Identities = 55/271 (20%), Positives = 109/271 (40%), Gaps = 38/271 (14%)
Query: 12 KLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL 71
+L KE AL + E ++ +++ + +++E +Q ++ +DEL ++ +L
Sbjct: 193 ELKKERALRKDEASKIT--IWKEQYRVVQEENQHMQMTIQALQDEL-----RIQRDLNQL 245
Query: 72 ELAEKKATDAEADVASLNRR-IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
+ + E VA L Q + E +R + L + LEE E + ++ +
Sbjct: 246 FQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ---TL 302
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
+R + ++ +E+ + + AK ED +R R+L E + E E E +
Sbjct: 303 NARDESIKKLLEMLQSKGLSAKATEEDHER-----TRRLAEAEMHVHHLESLLEQKEKEN 357
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+ L EE+ N S K K +T E + ++ +E
Sbjct: 358 SMLREEMHRRFENAPD----------------------SAKTKALQTVIEMKDSKISSME 395
Query: 251 KSIDDLEDELYAQKLKYKAISEELDHALNDM 281
+ + DLE+E+ K +EE + + M
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEEREEEMKQM 426
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 79.0 bits (193), Expect = 5e-15
Identities = 77/319 (24%), Positives = 150/319 (47%), Gaps = 67/319 (21%)
Query: 5 KKKMQMLKLDKENALD-------RAEQAEADKKAAE-DRSKQLEDELVSLQK-----KLK 51
K+K +M+K +++ + AE+ EA ++ E DR ++L+DE+V Q KL
Sbjct: 170 KRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLY 229
Query: 52 GTEDELDKYSEALKDAQEKLELAEKKATDAE-------ADVASLNRRIQLVEEELD---- 100
E E++K ++ L +++E +K+ E ++ + R Q +E+E+
Sbjct: 230 HNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDS 289
Query: 101 ----------RAQERLATALQKLEEAEKAA--------------DESERGMKVIESRAQK 136
+A+E + ++KLE A+K+ DE E+ M +E Q+
Sbjct: 290 ELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQE 349
Query: 137 DEEKME-----------IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
EE+ME ++E Q+K+ + E+A ++ +A++L D + ++R +L
Sbjct: 350 FEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL 409
Query: 186 SEGKCAELE----EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E K E E ++L+ + N K +E + E+Y + EE K L +L E E
Sbjct: 410 EERKKVETEAKIKQKLREIEENQKRIE-KLEEYITTSKQSLEEQKKLEGELTE---EVEM 465
Query: 242 AERSVTKLEKSIDDLEDEL 260
A+R + ++ K ++ + ++L
Sbjct: 466 AKRRIDEINKELNQVMEQL 484
Score = 59.7 bits (143), Expect = 3e-09
Identities = 49/184 (26%), Positives = 92/184 (50%), Gaps = 20/184 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----- 55
MD ++K+M L E A E+ ++ ++ R LE+ V +LK
Sbjct: 333 MDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAAT 388
Query: 56 ---ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
EL+K++ K Q++L+L E+K + EA + R I+ ++ +++ +E + T+ Q
Sbjct: 389 LAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQS 448
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEI--QLKEAKHIAEDADRKYEEVARKLV 170
LEE +K E E +V ++ + DE E+ ++ QL +A+ +++ R+ RK
Sbjct: 449 LEEQKKL--EGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQ----QRKAE 502
Query: 171 IIES 174
I+ES
Sbjct: 503 IMES 506
Score = 46.6 bits (109), Expect = 2e-05
Identities = 51/224 (22%), Positives = 106/224 (47%), Gaps = 38/224 (16%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSK----------QLEDELVSLQKKLKGTE 54
+K+ Q +K KEN + ++ EA KK+ ++ K +LE E++S++K + E
Sbjct: 293 QKRPQYIKA-KENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 55 DELDKYSEA------LKDAQEKL-----ELAEKKATDAEADVASLNR-------RIQLVE 96
+ +++ S++ L++ Q K E A K+A ++ NR R+ L E
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ + ++ L+++EE +K ++ E + I + Q EE+ +++ E E
Sbjct: 412 RKKVETEAKIKQKLREIEENQKRIEKLE---EYITTSKQSLEEQKKLE----GELTEEVE 464
Query: 157 DADRKYEEVARKLVIIESDL--ERAEERAELSEGKCAELEEELK 198
A R+ +E+ ++L + L R + + + + AE+ E +K
Sbjct: 465 MAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIK 508
Score = 45.1 bits (105), Expect = 7e-05
Identities = 57/253 (22%), Positives = 109/253 (43%), Gaps = 26/253 (10%)
Query: 29 KKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASL 88
++ AEDR+ S + K+ +L +YSE L EKL + K +
Sbjct: 86 EEGAEDRTFARVIVGGSSEYKINNKVVQLHEYSEEL----EKLGILIKAR-----NFLVF 136
Query: 89 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
++ + + + + L + + E + D+ ++ M E Q + + + +
Sbjct: 137 QGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAER 196
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE 208
KEAK E+ADR Y+ + ++V RA+ + +L K E E++ + L S
Sbjct: 197 KEAKQEKEEADR-YQRLKDEVV-------RAQVQLQLF--KLYHNEVEIEKLNKELASKN 246
Query: 209 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
+ EK ++ D+ E+E+K +K KE R ++EK I + + EL ++ +Y
Sbjct: 247 KEIEKDKKRMDKVEDELK---EKKKELGKMM----REQQQIEKEIKEKDSELNQKRPQYI 299
Query: 269 AISEELDHALNDM 281
E H + +
Sbjct: 300 KAKENTSHKIKKL 312
Score = 44.7 bits (104), Expect = 9e-05
Identities = 37/232 (15%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
E K+ E+E+ L+K+ + +D+ L+D + + + + D ++ + +++
Sbjct: 839 EQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKL 898
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
+E+ Q+ + KLE+ + K+ + + + M+ +I +E
Sbjct: 899 GGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMD--DISQEEGS 956
Query: 153 HIAEDA---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
ED+ ++ + + +IE D E + ++ + E+++E+ T+ L ++
Sbjct: 957 SQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAE-EEIKQEMNTLQQKLNEQQS 1015
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELY 261
++ + + E+++ + DK +E E A + K +++ + ++ E +
Sbjct: 1016 VLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERF 1067
Score = 38.9 bits (89), Expect = 0.005
Identities = 41/192 (21%), Positives = 88/192 (45%), Gaps = 22/192 (11%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
+++SK LE EL + ++ + + +KD +EK+ E + + +
Sbjct: 732 QEKSK-LESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIR 790
Query: 93 QLVEEELDR----AQERLATALQK------LEEAEKAADESERGMKVIESRAQKDEEKME 142
+ EE++ R A++RL QK L+ + E + + + E +KDE E
Sbjct: 791 EFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDEN--E 848
Query: 143 IQEIQLKEAKH-------IAEDADRKYEEVARKLVIIESDLERAEERAEL--SEGKCAEL 193
I++++ +E +H +A+ D K + +A+K + + + E E R +L + + L
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 194 EEELKTVTNNLK 205
++E+ + L+
Sbjct: 909 QKEVTAIETKLE 920
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/118 (20%), Positives = 54/118 (45%), Gaps = 22/118 (18%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+ +I + ++++D + + + A+A++ +++ E+ +LQ+KL + L +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEE--------EIKQEMNTLQQKLNEQQSVLQRI 1020
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ A EKLE S+ + Q +E + A++R A Q E+ +K
Sbjct: 1021 AAPNMKAMEKLE--------------SVRDKFQETSDEFEAARKRAKKAKQAFEQIKK 1064
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 78.6 bits (192), Expect = 6e-15
Identities = 67/286 (23%), Positives = 135/286 (47%), Gaps = 22/286 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1702
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 72.8 bits (177), Expect = 3e-13
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+ ++ E+ + ER +L + ++E A K K+K+ L+
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1820
Score = 71.2 bits (173), Expect = 9e-13
Identities = 59/247 (23%), Positives = 119/247 (48%), Gaps = 16/247 (6%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 969
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-------KSIDDLEDELYAQKLKYKAIS 271
+++E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 272 EELDHAL 278
EEL AL
Sbjct: 1090 EELQAAL 1096
Score = 66.6 bits (161), Expect = 2e-11
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1161 STATQQE-LRAKREQEVTVLKKALDEET--RSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 116 AEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ + +V+ Q+ E K + E Q++E + D +R E
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA-------QAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ EEE L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/239 (19%), Positives = 119/239 (49%), Gaps = 15/239 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1758 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ ++ E+ +E
Sbjct: 1813 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
Query: 182 RAELSEGKCAEL-------EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 233
+AE + +L EEE + + N + L+ + ++ ++ + E+ L KL+
Sbjct: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 62.4 bits (150), Expect = 4e-10
Identities = 64/289 (22%), Positives = 131/289 (45%), Gaps = 34/289 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1108
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1109 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 236 --ETRAEFAERSVTKLEKSIDD----LEDELYAQKLKYKAISEELDHAL 278
E RA+ E+ VT L+K++D+ E ++ + K+ EEL L
Sbjct: 1165 QQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1212
Score = 62.4 bits (150), Expect = 4e-10
Identities = 60/295 (20%), Positives = 134/295 (45%), Gaps = 36/295 (12%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L+
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 115 ----EAEKAAD-------------ESERGM-KVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ E+A ES GM E +A K + + QL++ + + +
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 157 DADRKYEEVARKLVIIESD-------LERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
+ R+ V+ KL +E + L+ E + E + L +L L+ +
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
E + + R+++EI+ L+ + +E + E++ +L++ +DDL +L Q+
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Score = 62.0 bits (149), Expect = 6e-10
Identities = 63/281 (22%), Positives = 133/281 (47%), Gaps = 12/281 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 908 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + + Q + + + + ++ L E +
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E +ELE LK + + LE K + E+I L ++ AE + +
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI--AELKMQ 1084
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
A++ +L+ ++ L+DE+ AQK EL+ ++D+
Sbjct: 1085 LAKKE-EELQAALARLDDEI-AQKNNALKKIRELEGHISDL 1123
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/277 (23%), Positives = 128/277 (46%), Gaps = 26/277 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ALK E+ + +A D + + + QL E E + ER AL A A
Sbjct: 1569 MQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL-----AAAAK 1619
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ E +K +E +A + E QL++ + +D R+ E+ I + + E
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
++A+ E +L+E+L A AE+ ++ D +EE L+++L + +
Sbjct: 1680 KKAKSLEADLMQLQEDL-----------AAAERARKQADLEKEE---LAEELASSLSGRN 1725
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
+ +LE I LE+EL ++ +A+S+ + A
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/271 (20%), Positives = 124/271 (45%), Gaps = 21/271 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1358
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1419 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1475 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
++V +LEKS LE ++ K + + + +EL
Sbjct: 1525 KNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 56.2 bits (134), Expect = 3e-08
Identities = 71/355 (20%), Positives = 140/355 (39%), Gaps = 74/355 (20%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELV-------SLQKK 49
+ A +KKM LD E L+ E A + +K AE + K+LEDE++ L K+
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 50 LKGTEDELDKYSEALKDAQEK-----------------LELAEKK--------------- 77
K E+ + + L + +EK LE+ KK
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1060
Query: 78 ---ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
A+D +A L +I ++ +L + +E L AL +L++ + + + ++ +E
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
+E ++ + +A+ D + E + +L E L+ + EL + E+
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVT 1177
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR------------AEFA 242
K + +S EAQ ++ QK + EE+ ++ K A+ A+ A
Sbjct: 1178 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 243 -------------ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
E KLE + +L+ + + +++++ N++ S+
Sbjct: 1238 GELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Score = 55.5 bits (132), Expect = 5e-08
Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 18/253 (7%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1475
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1536 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1588
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 248 KLEKSIDDLEDEL 260
KL+ + D + EL
Sbjct: 1649 KLQAQMKDFQREL 1661
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 904
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE---- 212
+A+ +A K +E L E R E E + +L+ E K + + LE Q E
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 213 ---KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA 269
K ++ E +IK L D++ + + + LE+ I DL L ++ K K
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 270 ISE 272
+++
Sbjct: 1025 LTK 1027
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE---ADVASLNRRIQ 93
+Q+E E Q K + + K E L +++ ++AE+ AE A V L R+++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
EEE R ++L+EA ++ + R + ++S+ ++ E + + +
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS-RRSGGRR 1946
Query: 154 IAEDADRKYEE 164
+ E+AD EE
Sbjct: 1947 VIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 78.6 bits (192), Expect = 6e-15
Identities = 67/286 (23%), Positives = 135/286 (47%), Gaps = 22/286 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1709
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1829
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1830 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 72.8 bits (177), Expect = 3e-13
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+ ++ E+ + ER +L + ++E A K K+K+ L+
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1827
Score = 71.2 bits (173), Expect = 9e-13
Identities = 59/247 (23%), Positives = 119/247 (48%), Gaps = 16/247 (6%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 976
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-------KSIDDLEDELYAQKLKYKAIS 271
+++E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 272 EELDHAL 278
EEL AL
Sbjct: 1097 EELQAAL 1103
Score = 66.6 bits (161), Expect = 2e-11
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1168 STATQQE-LRAKREQEVTVLKKALDEET--RSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 116 AEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ + +V+ Q+ E K + E Q++E + D +R E
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA-------QAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ EEE L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/239 (19%), Positives = 119/239 (49%), Gaps = 15/239 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1705 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1765 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ ++ E+ +E
Sbjct: 1820 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1877
Query: 182 RAELSEGKCAEL-------EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 233
+AE + +L EEE + + N + L+ + ++ ++ + E+ L KL+
Sbjct: 1878 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 62.4 bits (150), Expect = 4e-10
Identities = 64/289 (22%), Positives = 131/289 (45%), Gaps = 34/289 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1115
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1116 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 236 --ETRAEFAERSVTKLEKSIDD----LEDELYAQKLKYKAISEELDHAL 278
E RA+ E+ VT L+K++D+ E ++ + K+ EEL L
Sbjct: 1172 QQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1219
Score = 62.4 bits (150), Expect = 4e-10
Identities = 60/295 (20%), Positives = 134/295 (45%), Gaps = 36/295 (12%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L+
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 115 ----EAEKAAD-------------ESERGM-KVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ E+A ES GM E +A K + + QL++ + + +
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 157 DADRKYEEVARKLVIIESD-------LERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
+ R+ V+ KL +E + L+ E + E + L +L L+ +
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1392
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
E + + R+++EI+ L+ + +E + E++ +L++ +DDL +L Q+
Sbjct: 1393 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Score = 62.0 bits (149), Expect = 6e-10
Identities = 63/281 (22%), Positives = 133/281 (47%), Gaps = 12/281 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 915 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + + Q + + + + ++ L E +
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E +ELE LK + + LE K + E+I L ++ AE + +
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI--AELKMQ 1091
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
A++ +L+ ++ L+DE+ AQK EL+ ++D+
Sbjct: 1092 LAKKE-EELQAALARLDDEI-AQKNNALKKIRELEGHISDL 1130
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/277 (23%), Positives = 128/277 (46%), Gaps = 26/277 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ALK E+ + +A D + + + QL E E + ER AL A A
Sbjct: 1576 MQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL-----AAAAK 1626
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ E +K +E +A + E QL++ + +D R+ E+ I + + E
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
++A+ E +L+E+L A AE+ ++ D +EE L+++L + +
Sbjct: 1687 KKAKSLEADLMQLQEDL-----------AAAERARKQADLEKEE---LAEELASSLSGRN 1732
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
+ +LE I LE+EL ++ +A+S+ + A
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/271 (20%), Positives = 124/271 (45%), Gaps = 21/271 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1365
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1426 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1482 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1531
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
++V +LEKS LE ++ K + + + +EL
Sbjct: 1532 KNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 56.2 bits (134), Expect = 3e-08
Identities = 71/355 (20%), Positives = 140/355 (39%), Gaps = 74/355 (20%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELV-------SLQKK 49
+ A +KKM LD E L+ E A + +K AE + K+LEDE++ L K+
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 50 LKGTEDELDKYSEALKDAQEK-----------------LELAEKK--------------- 77
K E+ + + L + +EK LE+ KK
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 78 ---ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
A+D +A L +I ++ +L + +E L AL +L++ + + + ++ +E
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
+E ++ + +A+ D + E + +L E L+ + EL + E+
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVT 1184
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR------------AEFA 242
K + +S EAQ ++ QK + EE+ ++ K A+ A+ A
Sbjct: 1185 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Query: 243 -------------ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
E KLE + +L+ + + +++++ N++ S+
Sbjct: 1245 GELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 55.5 bits (132), Expect = 5e-08
Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 18/253 (7%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1482
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1483 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1542
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1543 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1595
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 248 KLEKSIDDLEDEL 260
KL+ + D + EL
Sbjct: 1656 KLQAQMKDFQREL 1668
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 911
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE---- 212
+A+ +A K +E L E R E E + +L+ E K + + LE Q E
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 213 ---KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA 269
K ++ E +IK L D++ + + + LE+ I DL L ++ K K
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 270 ISE 272
+++
Sbjct: 1032 LTK 1034
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE---ADVASLNRRIQ 93
+Q+E E Q K + + K E L +++ ++AE+ AE A V L R+++
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
EEE R ++L+EA ++ + R + ++S+ ++ E + + +
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS-RRSGGRR 1953
Query: 154 IAEDADRKYEE 164
+ E+AD EE
Sbjct: 1954 VIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 78.6 bits (192), Expect = 6e-15
Identities = 67/286 (23%), Positives = 135/286 (47%), Gaps = 22/286 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1709
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1829
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1830 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 72.8 bits (177), Expect = 3e-13
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+ ++ E+ + ER +L + ++E A K K+K+ L+
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1827
Score = 71.2 bits (173), Expect = 9e-13
Identities = 59/247 (23%), Positives = 119/247 (48%), Gaps = 16/247 (6%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 976
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-------KSIDDLEDELYAQKLKYKAIS 271
+++E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 272 EELDHAL 278
EEL AL
Sbjct: 1097 EELQAAL 1103
Score = 66.6 bits (161), Expect = 2e-11
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1168 STATQQE-LRAKREQEVTVLKKALDEET--RSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 116 AEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ + +V+ Q+ E K + E Q++E + D +R E
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA-------QAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ EEE L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/239 (19%), Positives = 119/239 (49%), Gaps = 15/239 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1705 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1765 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ ++ E+ +E
Sbjct: 1820 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1877
Query: 182 RAELSEGKCAEL-------EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 233
+AE + +L EEE + + N + L+ + ++ ++ + E+ L KL+
Sbjct: 1878 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 62.4 bits (150), Expect = 4e-10
Identities = 64/289 (22%), Positives = 131/289 (45%), Gaps = 34/289 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1115
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1116 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 236 --ETRAEFAERSVTKLEKSIDD----LEDELYAQKLKYKAISEELDHAL 278
E RA+ E+ VT L+K++D+ E ++ + K+ EEL L
Sbjct: 1172 QQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1219
Score = 62.4 bits (150), Expect = 4e-10
Identities = 60/295 (20%), Positives = 134/295 (45%), Gaps = 36/295 (12%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L+
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 115 ----EAEKAAD-------------ESERGM-KVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ E+A ES GM E +A K + + QL++ + + +
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 157 DADRKYEEVARKLVIIESD-------LERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
+ R+ V+ KL +E + L+ E + E + L +L L+ +
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1392
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
E + + R+++EI+ L+ + +E + E++ +L++ +DDL +L Q+
Sbjct: 1393 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Score = 62.0 bits (149), Expect = 6e-10
Identities = 63/281 (22%), Positives = 133/281 (47%), Gaps = 12/281 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 915 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + + Q + + + + ++ L E +
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E +ELE LK + + LE K + E+I L ++ AE + +
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI--AELKMQ 1091
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
A++ +L+ ++ L+DE+ AQK EL+ ++D+
Sbjct: 1092 LAKKE-EELQAALARLDDEI-AQKNNALKKIRELEGHISDL 1130
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/277 (23%), Positives = 128/277 (46%), Gaps = 26/277 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ALK E+ + +A D + + + QL E E + ER AL A A
Sbjct: 1576 MQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL-----AAAAK 1626
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ E +K +E +A + E QL++ + +D R+ E+ I + + E
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
++A+ E +L+E+L A AE+ ++ D +EE L+++L + +
Sbjct: 1687 KKAKSLEADLMQLQEDL-----------AAAERARKQADLEKEE---LAEELASSLSGRN 1732
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
+ +LE I LE+EL ++ +A+S+ + A
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/271 (20%), Positives = 124/271 (45%), Gaps = 21/271 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1365
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1426 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1482 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1531
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
++V +LEKS LE ++ K + + + +EL
Sbjct: 1532 KNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 56.2 bits (134), Expect = 3e-08
Identities = 71/355 (20%), Positives = 140/355 (39%), Gaps = 74/355 (20%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELV-------SLQKK 49
+ A +KKM LD E L+ E A + +K AE + K+LEDE++ L K+
Sbjct: 948 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Query: 50 LKGTEDELDKYSEALKDAQEK-----------------LELAEKK--------------- 77
K E+ + + L + +EK LE+ KK
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 78 ---ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
A+D +A L +I ++ +L + +E L AL +L++ + + + ++ +E
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
+E ++ + +A+ D + E + +L E L+ + EL + E+
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVT 1184
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR------------AEFA 242
K + +S EAQ ++ QK + EE+ ++ K A+ A+ A
Sbjct: 1185 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Query: 243 -------------ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
E KLE + +L+ + + +++++ N++ S+
Sbjct: 1245 GELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 55.5 bits (132), Expect = 5e-08
Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 18/253 (7%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1482
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1483 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1542
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1543 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1595
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 248 KLEKSIDDLEDEL 260
KL+ + D + EL
Sbjct: 1656 KLQAQMKDFQREL 1668
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 911
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE---- 212
+A+ +A K +E L E R E E + +L+ E K + + LE Q E
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 213 ---KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA 269
K ++ E +IK L D++ + + + LE+ I DL L ++ K K
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 270 ISE 272
+++
Sbjct: 1032 LTK 1034
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 78.6 bits (192), Expect = 6e-15
Identities = 67/286 (23%), Positives = 135/286 (47%), Gaps = 22/286 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1702
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 72.8 bits (177), Expect = 3e-13
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+ ++ E+ + ER +L + ++E A K K+K+ L+
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1820
Score = 71.2 bits (173), Expect = 9e-13
Identities = 59/247 (23%), Positives = 119/247 (48%), Gaps = 16/247 (6%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 969
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-------KSIDDLEDELYAQKLKYKAIS 271
+++E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 272 EELDHAL 278
EEL AL
Sbjct: 1090 EELQAAL 1096
Score = 66.6 bits (161), Expect = 2e-11
Identities = 68/295 (23%), Positives = 136/295 (46%), Gaps = 27/295 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1161 STATQQE-LRAKREQEVTVLKKALDEET--RSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 116 AEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ + +V+ Q+ E K + E Q++E + D +R E
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA-------QAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ EEE L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/239 (19%), Positives = 119/239 (49%), Gaps = 15/239 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1758 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ ++ E+ +E
Sbjct: 1813 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
Query: 182 RAELSEGKCAEL-------EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 233
+AE + +L EEE + + N + L+ + ++ ++ + E+ L KL+
Sbjct: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 62.4 bits (150), Expect = 4e-10
Identities = 64/289 (22%), Positives = 131/289 (45%), Gaps = 34/289 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1108
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1109 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 236 --ETRAEFAERSVTKLEKSIDD----LEDELYAQKLKYKAISEELDHAL 278
E RA+ E+ VT L+K++D+ E ++ + K+ EEL L
Sbjct: 1165 QQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1212
Score = 62.4 bits (150), Expect = 4e-10
Identities = 60/295 (20%), Positives = 134/295 (45%), Gaps = 36/295 (12%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L+
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 115 ----EAEKAAD-------------ESERGM-KVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ E+A ES GM E +A K + + QL++ + + +
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 157 DADRKYEEVARKLVIIESD-------LERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
+ R+ V+ KL +E + L+ E + E + L +L L+ +
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
E + + R+++EI+ L+ + +E + E++ +L++ +DDL +L Q+
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Score = 62.0 bits (149), Expect = 6e-10
Identities = 63/281 (22%), Positives = 133/281 (47%), Gaps = 12/281 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 908 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + + Q + + + + ++ L E +
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E +ELE LK + + LE K + E+I L ++ AE + +
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI--AELKMQ 1084
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
A++ +L+ ++ L+DE+ AQK EL+ ++D+
Sbjct: 1085 LAKKE-EELQAALARLDDEI-AQKNNALKKIRELEGHISDL 1123
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/277 (23%), Positives = 128/277 (46%), Gaps = 26/277 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ALK E+ + +A D + + + QL E E + ER AL A A
Sbjct: 1569 MQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL-----AAAAK 1619
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ E +K +E +A + E QL++ + +D R+ E+ I + + E
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
++A+ E +L+E+L A AE+ ++ D +EE L+++L + +
Sbjct: 1680 KKAKSLEADLMQLQEDL-----------AAAERARKQADLEKEE---LAEELASSLSGRN 1725
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
+ +LE I LE+EL ++ +A+S+ + A
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/271 (20%), Positives = 124/271 (45%), Gaps = 21/271 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1358
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1419 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1475 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
++V +LEKS LE ++ K + + + +EL
Sbjct: 1525 KNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 56.2 bits (134), Expect = 3e-08
Identities = 71/355 (20%), Positives = 140/355 (39%), Gaps = 74/355 (20%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELV-------SLQKK 49
+ A +KKM LD E L+ E A + +K AE + K+LEDE++ L K+
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 50 LKGTEDELDKYSEALKDAQEK-----------------LELAEKK--------------- 77
K E+ + + L + +EK LE+ KK
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1060
Query: 78 ---ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
A+D +A L +I ++ +L + +E L AL +L++ + + + ++ +E
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
+E ++ + +A+ D + E + +L E L+ + EL + E+
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL---EDTLDSTATQQELRAKREQEVT 1177
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR------------AEFA 242
K + +S EAQ ++ QK + EE+ ++ K A+ A+ A
Sbjct: 1178 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 243 -------------ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
E KLE + +L+ + + +++++ N++ S+
Sbjct: 1238 GELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Score = 55.5 bits (132), Expect = 5e-08
Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 18/253 (7%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1475
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1536 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1588
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 248 KLEKSIDDLEDEL 260
KL+ + D + EL
Sbjct: 1649 KLQAQMKDFQREL 1661
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 904
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE---- 212
+A+ +A K +E L E R E E + +L+ E K + + LE Q E
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 213 ---KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKA 269
K ++ E +IK L D++ + + + LE+ I DL L ++ K K
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 270 ISE 272
+++
Sbjct: 1025 LTK 1027
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 76.6 bits (187), Expect = 2e-14
Identities = 68/264 (25%), Positives = 123/264 (46%), Gaps = 23/264 (8%)
Query: 9 QMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ 68
QML L +R + E + E+R ++ E+ L +++L+ E+ L + E L + +
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE 247
Query: 69 EKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
E+L E++ + E + R++ EE L +ERL ++L E E+ E E ++
Sbjct: 248 ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLR 307
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E R + EE++ QE +L E + + +R EEV + ++E + + E+ L
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKL-PGQERLLEEVEK---LLEQERRQEEQERLLERE 363
Query: 189 KCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE-EEIKVLSDKL---------KEAETR 238
+ E EEL + L Q E+ Q+E E E ++ L L + AE R
Sbjct: 364 RLLEEVEELL----EQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPR 419
Query: 239 AEFAE-----RSVTKLEKSIDDLE 257
+ F E +S +LE+ + +L+
Sbjct: 420 SGFEELNNENKSTLQLEQQVKELK 443
Score = 70.1 bits (170), Expect = 2e-12
Identities = 63/274 (22%), Positives = 129/274 (47%), Gaps = 16/274 (5%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++K+++ + + ++ + + E+R ++ E+ L +++L+ E+ L + E
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L++ +E+L E++ + E + R+ EE L +ERL ++L E E+ E
Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQ 288
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E ++ E R + EE++ QE +L ++ + + E +R E+ KL E LE E+
Sbjct: 289 EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKL 346
Query: 183 AELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 242
E +EE + + + LE E Q+ R ++E + L+E E E
Sbjct: 347 LEQE-----RRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRE-- 399
Query: 243 ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
LE+ ++ + LY Q+ + ++ EEL++
Sbjct: 400 ------LERMLELGWEALYEQRAEPRSGFEELNN 427
Score = 65.9 bits (159), Expect = 4e-11
Identities = 66/260 (25%), Positives = 112/260 (43%), Gaps = 20/260 (7%)
Query: 10 MLKLDKENALDRAEQAEADKKAAE---DRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
+ KL + A A + A E D + L EL S+ ++L+ + S +
Sbjct: 137 LFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR 196
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+E+L E++ + E + R+ EE L +ERL ++L E E+ E E
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
+ E R + EE++ QE +L E + + + + E +L E L EER
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316
Query: 187 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
E + E EE L + EK +E EE +KL E E R E ER +
Sbjct: 317 EERLREQEERL-----------CEQEKLPGQERLLEE-----VEKLLEQERRQEEQERLL 360
Query: 247 TKLEKSIDDLEDELYAQKLK 266
+ E+ ++++E+ L ++L+
Sbjct: 361 ER-ERLLEEVEELLEQERLR 379
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 76.3 bits (186), Expect = 3e-14
Identities = 66/269 (24%), Positives = 122/269 (45%), Gaps = 15/269 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K+++ L+ ++ E+A A + +SK+ E +L SL+ ++ ++EL
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700
Query: 62 EALKDA-QEKLELAEKKATDAEADVASLNR------RIQLVEEELDRAQERLATALQKLE 114
A + A QE+ ELA++ A A L+ RI +EEEL+ Q + +
Sbjct: 1701 RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFR 1760
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV-IIE 173
+ D + S AQK + + E Q KE K ++ + + + + +E
Sbjct: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALE 1820
Query: 174 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEI-------K 226
+ + + EE+ E + A + ++ LK + Q E + D+Y+E++ K
Sbjct: 1821 AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 227 VLSDKLKEAETRAEFAERSVTKLEKSIDD 255
L +L+EAE A A S KL++ +DD
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 68.6 bits (166), Expect = 6e-12
Identities = 59/271 (21%), Positives = 130/271 (47%), Gaps = 12/271 (4%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
++ M+ L K++ + E K+A E + +++ +L L+ +L+ TED L+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEEL--DRAQERLATALQK-----L 113
+A+K AQ + +L + + E L ++++ +E EL +R Q LA A +K L
Sbjct: 1569 MQAMK-AQFERDLQTRDEQNEEKK-RLLIKQVRELEAELEDERKQRALAVASKKKMEIDL 1626
Query: 114 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 173
++ E + + + + + +K + +M+ + +L+EA+ ++ + +E +KL +E
Sbjct: 1627 KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1686
Query: 174 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 233
+++ + +E SE E+E + + + + + ++ R E I L ++L+
Sbjct: 1687 AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELE 1746
Query: 234 EAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
E ++ E K +D L EL A++
Sbjct: 1747 EEQSNMELLNDRFRKTTLQVDTLNAELAAER 1777
Score = 68.2 bits (165), Expect = 8e-12
Identities = 68/280 (24%), Positives = 133/280 (47%), Gaps = 20/280 (7%)
Query: 4 IKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
++ MQ +K E L R EQ E K+ + ++LE EL EDE + +
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL----------EDERKQRAL 1614
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
A+ +++K+E+ K D EA + + N+ V ++L + Q ++ ++LEEA + DE
Sbjct: 1615 AVA-SKKKMEIDLK---DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDE 1670
Query: 123 SERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
K E + + E E +++QE +L ++ A+++ +E+A ++ S +
Sbjct: 1671 IFAQSKESEKKLKSLEAEILQLQE-ELASSERARRHAEQERDELADEITNSASGKSALLD 1729
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E + A+LEEEL+ +N++ L + K + + D E+ ++++ +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQ 1789
Query: 242 AERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
ER +L+ + +LE A K K+KA L+ + +
Sbjct: 1790 LERQNKELKAKLQELEG---AVKSKFKATISALEAKIGQL 1826
Score = 66.6 bits (161), Expect = 2e-11
Identities = 62/251 (24%), Positives = 121/251 (48%), Gaps = 28/251 (11%)
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E L+ E+L ++K T E ++ + R+ Q + EE + E+L + E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 116 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE---V 165
AE+ E E + +ESR +++EE+ +I + + K+ + +D + + +E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 166 ARKL----VIIESDLERAEERAELSEGKCAE-------LEEELKTVTNNLKSLEAQAEKY 214
+KL V E+ +++ EE L E + ++ +E+ + ++ L E +A+
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED---ELYAQ----KLKY 267
++ ++ E I L ++LK+ E + E++ KL+ DL+D EL AQ KL+
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL 1085
Query: 268 KAISEELDHAL 278
EEL AL
Sbjct: 1086 AKKEEELQGAL 1096
Score = 64.7 bits (156), Expect = 9e-11
Identities = 62/277 (22%), Positives = 122/277 (44%), Gaps = 15/277 (5%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA-LKDAQEKLELA---EKKA 78
E +A + AE + + L +EL +L+ +L+ T D E K QE EL E++
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 79 TDAEADVASLNRR----IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
+ EA + + +R ++ + E+L++A+ A + + E E +KV++
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGK----- 189
+ E K + + Q++E + DR E+A K ++++L+ E +E K
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 190 --CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
A LE +L+ L+ Q S + + EEE L ++ +E E + E+ V
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 248 KLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
L+ + D + ++ +++ E L D ++
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEAL 1404
Score = 64.3 bits (155), Expect = 1e-10
Identities = 73/301 (24%), Positives = 135/301 (44%), Gaps = 25/301 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE-------DE 56
++K Q L+ D + + + K +E + K+L+ ++ L K+ + ++
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKL 113
K L + LE AEKK D ASL ++Q +E E R + L++ +++L
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL 1341
Query: 114 EEAEKAADESERGMKVIESRAQKDEEKMEIQ-EIQLKEAKHIAED---ADRKYEEVARKL 169
EE + + E + E A+K+ EK + + QL + K +D EE +KL
Sbjct: 1342 EEEKNSLQEQQEE----EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL 1397
Query: 170 V-IIESDLERAEERA---ELSEGKCAELEEELKTVTNNL---KSLEAQAEKYSQKEDRYE 222
+ E+ +R EE+A + E L++EL +T +L + + + EK +K D+
Sbjct: 1398 LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMT 282
E K +S + E RAE R S+ +E K +++ +++L + D+
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 283 S 283
S
Sbjct: 1518 S 1518
Score = 63.5 bits (153), Expect = 2e-10
Identities = 60/300 (20%), Positives = 135/300 (45%), Gaps = 31/300 (10%)
Query: 4 IKKKMQMLKLDKENALD----------RAEQAEAD-KKAAEDRSKQLEDELVSLQKKLKG 52
+ ++++ LK + E+ LD + EQ A+ KKA E+ +K E ++ ++++
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+EL + E K + LE ++ ++A + +Q V+ E + +++L +Q+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
L D R + E+ ++Q +L + E+A++K + A+ +
Sbjct: 1264 LHAKVSEGD---------RLRVELAEKASKLQN-ELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
ES L+ +E + + L ++ + SL+ Q E+ + E+++ L +L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 233 KEAETRAEFAERSVTKLEKSIDDL--EDELYAQKLKYKAIS--------EELDHALNDMT 282
+ + + + ++ LE++ L + E +Q+L+ KA++ L L+D+T
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433
Score = 63.2 bits (152), Expect = 3e-10
Identities = 61/272 (22%), Positives = 126/272 (46%), Gaps = 20/272 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
+KK L L +E ++ E D+ AE R K E + +SL + L+ + +++
Sbjct: 1450 QKKFDQL-LAEEKSISARYAEERDRAEAEAREK--ETKALSLARALEEALEAKEEFERQN 1506
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ---ERLATALQKLEEAEKAAD 121
K + +E D +V L + + +E++++ + E L LQ E+A+ +
Sbjct: 1507 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
Query: 122 ESERGMKV-----IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA----RKLVII 172
+ + MK +++R +++EEK + Q++E + ED +RK +A +K+ I
Sbjct: 1567 VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED-ERKQRALAVASKKKMEID 1625
Query: 173 ESDLERAEERAELSEG----KCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
DLE E A + + +L+ ++K L+ A ++ + E+++K L
Sbjct: 1626 LKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSL 1685
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
++ + + +ER+ E+ D+L DE+
Sbjct: 1686 EAEILQLQEELASSERARRHAEQERDELADEI 1717
Score = 61.2 bits (147), Expect = 1e-09
Identities = 72/289 (24%), Positives = 131/289 (45%), Gaps = 39/289 (13%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+D + Q L+L+K AEA K E+ LED+ K+ K ED + +
Sbjct: 959 LDEEEGARQKLQLEKVT-------AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
S L + +EK + K E ++ L R++ +EE R Q+LE+A++
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLEERLK--KEEKTR---------QELEKAKRKL 1060
Query: 121 DESERGM--KVIESRAQKDEEKMEI--QEIQLKEAKHIAED-------ADRKYEEVARKL 169
D + ++ E +AQ DE K+++ +E +L+ A +D A + E+ ++
Sbjct: 1061 DGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQI 1120
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLK----SLEAQAEKYSQKEDRYEEEI 225
++ D E + +E + +L EEL+ + L+ + AQ E +++E E
Sbjct: 1121 AELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Query: 226 KVLSDKLKEAETR-AEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
K L ++ K E + + +R T LE+ + LE Q ++KA E+
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLE-----QAKRFKANLEK 1224
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/276 (20%), Positives = 126/276 (45%), Gaps = 22/276 (7%)
Query: 1 MDAIKKKMQMLKLDKENAL--DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
++ + + ++ K+++E L D+ + +KK EDR + +L ++K K +
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 59 KYSEALKDAQEKLELAEK--------------KATDAEADVASLNRRIQLVEEELDRAQE 104
K + D +E+L+ EK + TD + +A L +I ++ +L + +E
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
L AL + ++ + + + ++ ++++ + +E E ++ +A+ D + E
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEA 1150
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
+ +L E L+ + EL + E+ E K + K+ EAQ + Q R+
Sbjct: 1151 LKTEL---EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ---RHATA 1204
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
++ LS++L++A+ E++ LE +L E+
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240
Score = 60.1 bits (144), Expect = 2e-09
Identities = 72/306 (23%), Positives = 132/306 (43%), Gaps = 59/306 (19%)
Query: 15 KENALDRAEQAEADKKA-------AEDRSKQLEDELVSLQKKLKGTEDELD--------- 58
K N R Q E +K + E+ K LE ++++LQ +L T+ ++D
Sbjct: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL 1390
Query: 59 --KYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQK- 112
+ LKDA+ + E+KA + + NR Q +++ +LD Q ++A+ L+K
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDH-QRQVASNLEKK 1449
Query: 113 ------------------LEEAEKAADESERGMKVIESRAQKDEEKMEIQ---EIQLKEA 151
EE ++A E+ S A+ EE +E + E Q K+
Sbjct: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL 1509
Query: 152 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN-------NL 204
+ ED ++V + + +E E++ E + ELE+EL+ + N+
Sbjct: 1510 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM 1569
Query: 205 KSLEAQAEKYSQKEDRYEEE--------IKVLSDKLKEAETRAEFAERSVTKLEKSIDDL 256
++++AQ E+ Q D EE ++ L +L++ + A S K+E + DL
Sbjct: 1570 QAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDL 1629
Query: 257 EDELYA 262
E ++ A
Sbjct: 1630 EAQIEA 1635
Score = 59.7 bits (143), Expect = 3e-09
Identities = 74/285 (25%), Positives = 137/285 (48%), Gaps = 47/285 (16%)
Query: 5 KKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELVSLQ-------KKLKGT 53
KKKMQ D E LD E A + +K AE + K++E+E++ L+ K+ K
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 54 EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 113
ED + + S L + +EK + K E ++ L R++ +EE R Q+L
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLK--KEEKTR---------QEL 1053
Query: 114 EEAEKAADESERGMK--VIESRAQKDEEKMEI--QEIQLKEAKHIAEDADRKYEEVARKL 169
E+A++ D ++ + E +AQ DE K+++ +E +L+ A +D + ++ A K+
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDD-ETLHKNNALKV 1112
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS 229
V EL + + AEL+E+ ++ K+ +AEK QK D EE++ L
Sbjct: 1113 V------------REL-QAQIAELQEDFESE----KASRNKAEK--QKRD-LSEELEALK 1152
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+L++ + TK E+ + +L+ L + ++A +++
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM 1197
Score = 57.4 bits (137), Expect = 1e-08
Identities = 66/295 (22%), Positives = 141/295 (47%), Gaps = 26/295 (8%)
Query: 2 DAIKKKMQMLKLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVS----LQKKLKGTEDE 56
+ +K K + K++ E ++R Q ++K Q E EL + ++ +L + E
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ-ERLATALQKLEE 115
L+ E L D + ++E E++ + + + IQ +EE+LD + R L+K+
Sbjct: 920 LE---EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV-T 975
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR---KLVII 172
AE + E + ++E + K ++ ++ E ++ E + + K + +A+ K ++
Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 1035
Query: 173 ESDLE---RAEE--RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
SDLE + EE R EL + K +L+ E + + + L+AQ ++ + + EEE++
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAK-RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKL-------KYKAISEELD 275
+ + A + V +L+ I +L+++ ++K + + +SEEL+
Sbjct: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 55.1 bits (131), Expect = 7e-08
Identities = 46/269 (17%), Positives = 125/269 (46%), Gaps = 12/269 (4%)
Query: 10 MLKLDKENALDRAEQAEADKKAAEDRSKQLEDEL---VSLQKKLKGTEDELDKYSEALKD 66
+L+ ++ + A+ A + + +D + L++E ++L +++ E+E + E ++
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+E + EK+ ++ +A +++ ++ +E L+ E + +E
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
+E + +++++ + L + +A + ++K ++ + L +S R E + +
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA 1474
Query: 187 EGKCAELEEELKTVTNNLK-SLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E + E E + ++ L+ +LEA+ E +E + K L +++ + + ++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEE--------FERQNKQLRADMEDLMSSKDDVGKN 1526
Query: 246 VTKLEKSIDDLEDELYAQKLKYKAISEEL 274
V +LEKS LE ++ + + + + +EL
Sbjct: 1527 VHELEKSKRALEQQVEEMRTQLEELEDEL 1555
Score = 46.6 bits (109), Expect = 2e-05
Identities = 45/196 (22%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
S +K +L++ ++ LK ++LE A K + +A +++L +I +EE+L++ +
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAVK--SKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A A + + EK E ++ A + +E+ME ++K+ K E+A+ EE
Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAE---EE 1892
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK---SLEAQAEKYSQKEDRY 221
R ++ E +EG L E+ T+ N L+ + + + +++
Sbjct: 1893 ATRANASRRKLQRELDDATEANEG----LSREVSTLKNRLRRGGPISFSSSRSGRRQLHL 1948
Query: 222 EEEIKVLSDKLKEAET 237
E LSD E++T
Sbjct: 1949 EGASLELSDDDTESKT 1964
Score = 43.1 bits (100), Expect = 3e-04
Identities = 30/133 (22%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 146 IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK 205
+Q+ + + D + +V K +E +LE E + + + L E+L+ T
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 206 SLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL----- 260
E + + K+ EE + L +++E E R + + K++ I DLE++L
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964
Query: 261 YAQKLKYKAISEE 273
QKL+ + ++ E
Sbjct: 965 ARQKLQLEKVTAE 977
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 17/155 (10%)
Query: 5 KKKMQMLKLDKENALDRAEQAEAD--KKAAEDRSKQLEDELVSLQ----KKLKGT----- 53
K +Q+ L+ E A +R+ ++D ++ E ++K+L+ +L L+ K K T
Sbjct: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALE 1820
Query: 54 ------EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLA 107
E++L++ ++ A + + EKK + V R +E++++A R+
Sbjct: 1821 AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
++LEEAE+ A + + ++ E E
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 75.9 bits (185), Expect = 4e-14
Identities = 55/282 (19%), Positives = 136/282 (48%), Gaps = 20/282 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 EALKDAQEKLELAEKKATDAEADV---------------ASLNRRIQLV--EEELDRAQE 104
E +++ +EK+ EKK E + + R+ + + +EE+ R +E
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
++ +K+ + E+ E ++ E + ++ EEKM QE +++E + + + ++ +E+
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
+ + E + E++ E K E EE++ ++ E + ++ +K + EE+
Sbjct: 557 ---EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLK 266
I+ +K++E E + E + + E+ + E+++ Q+ K
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 72.8 bits (177), Expect = 3e-13
Identities = 50/238 (21%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA---DVASLN 89
+++ + E+++ ++K+ E+++ + E +++ +EK+ E+K + E + ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 90 RRIQLVEEELDRAQE-RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
+ ++ EEE + QE ++ +K+ E E+ E ++ E + Q+ EEKM QE ++
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE 208
+E + ++ + K E K+ E + EE+ E K E EE+++ + E
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 209 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLK 266
+ + +K EE+I+ + ++E E + E + + E+ + + E+++ Q+ K
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 72.8 bits (177), Expect = 3e-13
Identities = 52/249 (20%), Positives = 119/249 (47%), Gaps = 12/249 (4%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEK------ 76
EQ E +K E +Q E+++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCA 191
+ Q+ EEK+ QE +++E + + ++ + K E K+ E ++ EE E K
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 ELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
E E++++ ++ E ++ +K EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 SIDDLEDEL 260
+ E+++
Sbjct: 739 RLRQQEEKM 747
Score = 71.6 bits (174), Expect = 7e-13
Identities = 50/236 (21%), Positives = 114/236 (48%), Gaps = 4/236 (1%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ +E + E+ ++ + K E E + ++K + ED++ +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K + E ++ EE++ +E++ +K+ E E+
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E + E + + EEKM QE +++E + + K E +K+ E + EE
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR-YEEEIKVLSDKLKEAE 236
+ E K E EE++ + ++ Q EK ++E++ +E+E+++ + K E
Sbjct: 697 MMQEQEEKMWEQEEKM---CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 68.2 bits (165), Expect = 8e-12
Identities = 63/250 (25%), Positives = 123/250 (49%), Gaps = 27/250 (10%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD + S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE + E E+ R+ EE+ + E + R EE E K EE +
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 201 TNNLKSLEA---QAEKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDL 256
++ LE + EK ++E++ +EE K+ +K +E E + E + + E+ I +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 257 EDELYAQKLK 266
E +++ Q+ K
Sbjct: 450 EKKMWRQEEK 459
Score = 68.2 bits (165), Expect = 8e-12
Identities = 64/286 (22%), Positives = 134/286 (46%), Gaps = 25/286 (8%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 283
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+E + ++ + +EK+ E+K + E + +I+ EE++ +E++ +
Sbjct: 284 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL--- 169
+ E E+ E M E + ++ EE M +E +++ + + + + K E+ K+
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Query: 170 -VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
I E + +R EE + K E E ++ ++ E + + +K R EE+I
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE- 462
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+K++E E R E + + + E+ I + ++E++ QK K E++
Sbjct: 463 QEKIREEEKRQE--QEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKI 505
Score = 67.0 bits (162), Expect = 2e-11
Identities = 60/285 (21%), Positives = 139/285 (48%), Gaps = 31/285 (10%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++ E+ + ++K++ E+++ + E ++
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIR 407
Query: 66 DAQEKLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ +EK + EK K + EA ++ EE++ +E++ +K+ E+
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEA-------KMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E E K+ E ++++E+M QE ++ E + I ++ +E+ K+ E + R E
Sbjct: 461 HEQE---KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ-EEKIRKQEEKVWRQE 516
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEA---------QAEKYSQKEDRYEEEIKV--LS 229
E+ E K E EE++ ++ E + EK ++E R E+E K+
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+K++E E + E + + E+ + E++++ Q+ K + E++
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Score = 63.9 bits (154), Expect = 2e-10
Identities = 45/212 (21%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Query: 12 KLDKENALDRAEQA--EADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE 69
K+ ++ + R E+ E +K E++ ++ ED++ ++K++ E+++ + E +++ +E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 70 KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
K + E+K E + +IQ EE++ +E++ + +E E+ E E M
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 130 IESRAQ-------KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E + Q + EEK+ QE +++E + + + +E K+ E + EE+
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Query: 183 AELSEGKCAELEEELKTVTNNLKSLEAQAEKY 214
+ E K EE++ L+ E + +++
Sbjct: 719 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 59.3 bits (142), Expect = 4e-09
Identities = 52/265 (19%), Positives = 124/265 (46%), Gaps = 16/265 (6%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ + E + E+ + E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 388 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA---RKLVIIESDLERAEERAELSEGKC 190
++ E+KM QE ++ E + I E+ R+ +E + + + ++ R +E+ E K
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDR-YEEEIKVLSDKLKEAETRAEFAERSVTKL 249
+ EE+ V + + Q EK ++E++ + +E K+ + E + + +
Sbjct: 506 RKQEEK---VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 250 EKSIDDLEDELYAQKLKYKAISEEL 274
EK + ED+++ Q+ K + E++
Sbjct: 563 EKR-QEQEDKMWRQEEKIREQEEKV 586
Score = 53.5 bits (127), Expect = 2e-07
Identities = 60/245 (24%), Positives = 108/245 (44%), Gaps = 21/245 (8%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAEKAADESERGMKVIESRA-- 134
++ + +V L R +L+RA +L Q+L+ EA+ E + ++++
Sbjct: 237 KSEIQLNVKELKR-------KLERA--KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 135 --------QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Q+ EEKM QE +++E + ++ + K E K+ E + R EE
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 187 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
E K EE + ++ E + +K R EE + +K++E E + E+
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 247 TKLEK 251
+ EK
Sbjct: 408 EQEEK 412
Score = 30.8 bits (68), Expect = 1.4
Identities = 37/188 (19%), Positives = 79/188 (42%), Gaps = 44/188 (23%)
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+ +L ++ K A E E+ + + ++ +K ADR EE+ ++
Sbjct: 164 ISRLHDSWKFAGELEQALSAVATQKKK---------------------ADRYIEELTKER 202
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSLEAQAEK--------- 213
+ +L R E + K A+L+E+L+ V + N+K L+ + E+
Sbjct: 203 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ 262
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEF-------AERSVTKLEKSIDDLEDELYAQKLK 266
+ D +E++ +S KL+ E E + + E+ I + E+++ Q+ K
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 267 YKAISEEL 274
+ E++
Sbjct: 323 IREQEEKI 330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.121 0.292
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,432,586
Number of Sequences: 37866
Number of extensions: 392709
Number of successful extensions: 16354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 770
Number of HSP's successfully gapped in prelim test: 1021
Number of HSP's that attempted gapping in prelim test: 3277
Number of HSP's gapped (non-prelim): 6680
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.