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Search of human proteins with 63252896
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 532 e-151
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 502 e-142
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 486 e-138
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 480 e-136
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 465 e-131
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 457 e-129
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 450 e-127
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 449 e-126
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 444 e-125
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 434 e-122
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 348 4e-96
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 344 4e-95
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 344 6e-95
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 324 5e-89
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 323 1e-88
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 303 1e-82
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 272 3e-73
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 88 1e-17
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 88 1e-17
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 84 2e-16
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 84 2e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 84 2e-16
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 80 2e-15
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 80 2e-15
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 80 2e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 3e-15
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 3e-15
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 77 1e-14
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 77 1e-14
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 77 1e-14
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 532 bits (1371), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 502 bits (1292), Expect = e-142
Identities = 268/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 486 bits (1251), Expect = e-138
Identities = 261/284 (91%), Positives = 272/284 (95%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 480 bits (1236), Expect = e-136
Identities = 257/284 (90%), Positives = 268/284 (94%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 465 bits (1196), Expect = e-131
Identities = 242/282 (85%), Positives = 265/282 (93%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 457 bits (1176), Expect = e-129
Identities = 246/284 (86%), Positives = 263/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 450 bits (1157), Expect = e-127
Identities = 241/284 (84%), Positives = 259/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 449 bits (1156), Expect = e-126
Identities = 236/284 (83%), Positives = 263/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 444 bits (1143), Expect = e-125
Identities = 231/284 (81%), Positives = 261/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 434 bits (1117), Expect = e-122
Identities = 226/284 (79%), Positives = 259/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E KC +LEEELK VTNNLKSLEAQA+KYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE++V K + ++ + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 348 bits (892), Expect = 4e-96
Identities = 189/238 (79%), Positives = 205/238 (86%)
Query: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 344 bits (883), Expect = 4e-95
Identities = 181/240 (75%), Positives = 208/240 (86%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/98 (27%), Positives = 48/98 (48%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E + KL+EAE A+ +ER + +E EEK+
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 344 bits (882), Expect = 6e-95
Identities = 178/242 (73%), Positives = 211/242 (87%)
Query: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
KYEEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+
Sbjct: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL E
Sbjct: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
Query: 281 LN 282
LN
Sbjct: 245 LN 246
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 324 bits (831), Expect = 5e-89
Identities = 173/237 (72%), Positives = 199/237 (83%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/98 (27%), Positives = 48/98 (48%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E + KL+EAE A+ +ER + +E EEK+
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 323 bits (828), Expect = 1e-88
Identities = 168/240 (70%), Positives = 201/240 (83%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/98 (27%), Positives = 48/98 (48%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E + KL+EAE A+ +ER + +E EEK+
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 303 bits (776), Expect = 1e-82
Identities = 160/237 (67%), Positives = 192/237 (81%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/98 (27%), Positives = 48/98 (48%)
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
E V RK+ +++ + AEERAE + + + + SL + + ++ DR +
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E + KL+EAE A+ +ER + +E EEK+
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 272 bits (695), Expect = 3e-73
Identities = 146/230 (63%), Positives = 181/230 (78%), Gaps = 7/230 (3%)
Query: 62 EALKDAQEKLELAEKKATD----AEADVASLNRRIQLVEEELDRAQERLATA---LQKLE 114
+A+K + L+L ++ A D AEAD R + +EEE Q++L ++K
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E
Sbjct: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKE
Sbjct: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 181
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
AETRAEFAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 182 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 87.8 bits (216), Expect = 1e-17
Identities = 58/250 (23%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL----KT 199
QE +++E + + +D + K EV K+ E ++ EE+ + E K E EE+ K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 200 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLS---------DKLKEAETRAEFAERSVTKLE 250
+ K E + + + Q+E +E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEEKV 260
+ +LEE++
Sbjct: 552 VRLQELEERL 561
Score = 81.3 bits (199), Expect = 9e-16
Identities = 63/246 (25%), Positives = 121/246 (49%), Gaps = 19/246 (7%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +KD + KLE A+ ++ EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE +++E + + K E K+ E + R EE+ + K E EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM--- 390
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ + Q EK +K R E++++ +K++E E E + +LE+ + D EEK+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AHAKEE 266
+E+
Sbjct: 451 REVEEK 456
Score = 81.3 bits (199), Expect = 9e-16
Identities = 59/259 (22%), Positives = 128/259 (49%), Gaps = 4/259 (1%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+++ K ++Q+ D + L+RA Q ++ + + +L EL S+ KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E ++ E + ++ EEKM QE +++E E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E+ E K E +E+++ + E + + + EE+++ + +K++E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 241 FAERSVTKLEKSIDDLEEK 259
E + + E+ I + EEK
Sbjct: 466 EQEEKIQRQEEKIQEQEEK 484
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/226 (25%), Positives = 115/226 (50%), Gaps = 8/226 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + ++ +E ++ + E + +++ ++ E+E+ ++K++ E+ + E L+
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ +EK++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEEEIK 226
G E + L T+T LKS EAQ+ Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 75.5 bits (184), Expect = 5e-14
Identities = 56/250 (22%), Positives = 123/250 (49%), Gaps = 16/250 (6%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE 82
+Q E E++ ++ E+++ + K++ E+++ + E + + +EK+ E K E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
+ +I+ EE++ R +E++ +K++E E +E R + I + +K +EKM
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQEKMW 409
Query: 143 IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN 202
QE +++E D K E ++ E + EE + E K E+EE+++
Sbjct: 410 RQEKKMREQ-------DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 203 NL----KSLEAQAEKYSQKEDRYEEEIKVL--SDKLKEAETRAEFAERSVTKLEKSIDDL 256
+ + ++ Q EK ++E++ + K+L +K+ E E + E + + E+ + +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 257 EEKVAHAKEE 266
EEK+ +E+
Sbjct: 523 EEKMQRQEEK 532
Score = 70.1 bits (170), Expect = 2e-12
Identities = 52/235 (22%), Positives = 112/235 (47%), Gaps = 16/235 (6%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ E + R EE+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWE 514
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E K E EE+++ ++ E + + +K E ++ L ++L + +AE
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 67.4 bits (163), Expect = 1e-11
Identities = 45/224 (20%), Positives = 111/224 (49%), Gaps = 6/224 (2%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + ++ + ++ +E ++ E+ ++ ++ ++++++ + ++ + ++ +K
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + ++K+ ++K + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR------KYEEVARKLVIIESD 175
E E ++ E + Q+ EEK QE LK+ + I E ++ K E K+ E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 219
++R EE+ E + + EE+++ L+ LE + K QK +
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 87.8 bits (216), Expect = 1e-17
Identities = 58/250 (23%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL----KT 199
QE +++E + + +D + K EV K+ E ++ EE+ + E K E EE+ K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 200 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLS---------DKLKEAETRAEFAERSVTKLE 250
+ K E + + + Q+E +E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEEKV 260
+ +LEE++
Sbjct: 552 VRLQELEERL 561
Score = 81.3 bits (199), Expect = 9e-16
Identities = 63/246 (25%), Positives = 121/246 (49%), Gaps = 19/246 (7%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +KD + KLE A+ ++ EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE +++E + + K E K+ E + R EE+ + K E EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM--- 390
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ + Q EK +K R E++++ +K++E E E + +LE+ + D EEK+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AHAKEE 266
+E+
Sbjct: 451 REVEEK 456
Score = 81.3 bits (199), Expect = 9e-16
Identities = 59/259 (22%), Positives = 128/259 (49%), Gaps = 4/259 (1%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+++ K ++Q+ D + L+RA Q ++ + + +L EL S+ KL+ +E + +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + +EK+ E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E ++ E + ++ EEKM QE +++E E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E+ E K E +E+++ + E + + + EE+++ + +K++E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 241 FAERSVTKLEKSIDDLEEK 259
E + + E+ I + EEK
Sbjct: 466 EQEEKIQRQEEKIQEQEEK 484
Score = 76.3 bits (186), Expect = 3e-14
Identities = 57/226 (25%), Positives = 115/226 (50%), Gaps = 8/226 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + ++ +E ++ + E + +++ ++ E+E+ ++K++ E+ + E L+
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ +EK++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEEEIK 226
G E + L T+T LKS EAQ+ Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 75.5 bits (184), Expect = 5e-14
Identities = 56/250 (22%), Positives = 123/250 (49%), Gaps = 16/250 (6%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE 82
+Q E E++ ++ E+++ + K++ E+++ + E + + +EK+ E K E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
+ +I+ EE++ R +E++ +K++E E +E R + I + +K +EKM
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQEKMW 409
Query: 143 IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN 202
QE +++E D K E ++ E + EE + E K E+EE+++
Sbjct: 410 RQEKKMREQ-------DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 203 NL----KSLEAQAEKYSQKEDRYEEEIKVL--SDKLKEAETRAEFAERSVTKLEKSIDDL 256
+ + ++ Q EK ++E++ + K+L +K+ E E + E + + E+ + +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 257 EEKVAHAKEE 266
EEK+ +E+
Sbjct: 523 EEKMQRQEEK 532
Score = 70.1 bits (170), Expect = 2e-12
Identities = 52/235 (22%), Positives = 112/235 (47%), Gaps = 16/235 (6%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ E + R EE+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWE 514
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
E K E EE+++ ++ E + + +K E ++ L ++L + +AE
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 67.4 bits (163), Expect = 1e-11
Identities = 45/224 (20%), Positives = 111/224 (49%), Gaps = 6/224 (2%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + ++ + ++ +E ++ E+ ++ ++ ++++++ + ++ + ++ +K
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + ++K+ ++K + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR------KYEEVARKLVIIESD 175
E E ++ E + Q+ EEK QE LK+ + I E ++ K E K+ E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 219
++R EE+ E + + EE+++ L+ LE + K QK +
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 83.6 bits (205), Expect = 2e-16
Identities = 66/277 (23%), Positives = 127/277 (45%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
+++ + +E L +A++ E K+ E QL++EL + ++ + + E D+ ++ +
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
++ K LA ++ EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD----RKYEE----VARKLVIIESDLE 177
+ + S AQK+E + E Q KE K ++ + KY+ + K+ +E L+
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 178 RAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
+ + + + E++LK V + AE+Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
A+ A S KL++ ++D E E S+ L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 72.4 bits (176), Expect = 4e-13
Identities = 62/305 (20%), Positives = 134/305 (43%), Gaps = 28/305 (9%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEA-----------DKKAAEDRSKQLEDELVSLQKKL 50
++ ++K+Q+ K+ E L + E+ + +KK EDR + L ++K
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 51 KGTEDELDKYSEALKDAQEKLELAEKK--------------ATDAEADVASLNRRIQLVE 96
K +K+ + D +E+L EK+ +TD +A L +I ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+L + +E L AL ++EE + + + ++ +ES+ + +E +E + +A+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 216
D + E + +L E L+ + EL + E+ KT+ K+ EAQ ++ Q
Sbjct: 1136 DLGEELEALKTEL---EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
K + EE+ ++ K + E A++++ + + + + K ++ + ++
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEA 1252
Query: 277 TLLEL 281
L EL
Sbjct: 1253 QLQEL 1257
Score = 72.0 bits (175), Expect = 6e-13
Identities = 59/270 (21%), Positives = 124/270 (45%), Gaps = 10/270 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
KK++ L+ + E A + AE + + L +EL +L+ +L+ T D E
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 66 DAQEKLELAEK----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++++ + +K +A EA + + ++ EEL E+ LE+A++
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL- 1222
Query: 122 ESERG-----MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
E+ERG +KV+ E K + E QL+E + + +R E+A K+ ++ +L
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 177 ERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
+ S+ K ++L ++ + + L+ + ++ ++++ ++K + D+
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ E E + LEK I L +VA K++
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Score = 67.4 bits (163), Expect = 1e-11
Identities = 76/326 (23%), Positives = 149/326 (45%), Gaps = 46/326 (14%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL----QKKLKGTEDELDK 59
++K + L+ E + E+ E + +A ED +LE L ++ ++ L+G +++ ++
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 60 YSEAL-----------KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
+ L +D +++ +A E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKYEEV 165
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R+ ++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 166 ARKLV--IIESDLERA---EERAELSEGKCAELEEEL-------KTVTNNLKSLEAQ--- 210
+L I S + A EE+ L E + A+LEEEL + + + LK Q
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRL-EARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 211 -----------AEKYSQKEDRYEEEIKVLSDKLKEAE-TRAEFAERSVTKLEKSIDDLEE 258
A+K + E + K L KL+E E T + S+T LE I LEE
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 259 KVAHAKEENLSMHQMLDQTLLELNNM 284
++ + +E + + + +T +L ++
Sbjct: 1822 QLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 65.9 bits (159), Expect = 4e-11
Identities = 55/252 (21%), Positives = 117/252 (46%), Gaps = 13/252 (5%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-EKLELAEKKATDAE--ADVASLN 89
E+ E+ELV +++K E+ L + EKL+L E+ + E A+ L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
R+ ++EL+ L ++EE E+ + K ++ Q+ EE++E +E +
Sbjct: 904 ARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
+ + + K +++ + +I+E + + +L E + AE T NL E
Sbjct: 961 KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-------TTNLTEEEE 1013
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269
+++ ++ ++++E I L ++L+ E + + E++ KLE DL +++A + +
Sbjct: 1014 KSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 270 MHQMLDQTLLEL 281
+ L + EL
Sbjct: 1074 LKMQLAKKEEEL 1085
Score = 62.8 bits (151), Expect = 3e-10
Identities = 69/304 (22%), Positives = 136/304 (44%), Gaps = 25/304 (8%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDE-LDKYSEA 63
+++ Q L+ +K+ ++ E + E ++L+ E V+ + KLK E+E + +
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 64 LKDAQEKLELAEKKA------TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K A+EK L ++ A T+ E SL + E + +ERL ++ +E E
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE 1047
Query: 118 KA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----RKYE 163
K D ++ ++ E +AQ E KM++ +E+Q A+ E A +K
Sbjct: 1048 KTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIR 1107
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
E+ ++ ++ DLE +E + +L EEL+ + L+ + + E+
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 224 EIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMH---QMLDQTLL 279
E+ +L L +EA+T + K +++++L E++ K ++ Q L+
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERG 1227
Query: 280 ELNN 283
EL N
Sbjct: 1228 ELAN 1231
Score = 62.4 bits (150), Expect = 4e-10
Identities = 71/317 (22%), Positives = 136/317 (42%), Gaps = 46/317 (14%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
++ K++ ++ +K + ++ E+ E K E + L ++ ++KK++ + L+ E
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA------QERLATALQKLEEA 116
+ Q+ LE ++ + A L + +++ELD Q + A L+K ++
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 117 --EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE----------- 163
+ A+E K E R + + E E + L A+ + E ++K E
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 164 ---------EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN-------NLKSL 207
+V + + +E E++ E + + ELE+EL+ + NL+++
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAM 1565
Query: 208 EAQAEKYSQKEDRYEEEIK---VLSDKLKEAETRAEFAERSVT-----KLEKSIDDLEEK 259
+AQ E+ Q D EE K V + EAE E +RS+ KLE + DLE
Sbjct: 1566 KAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE-- 1623
Query: 260 VAHAKEENLSMHQMLDQ 276
AH N + + + Q
Sbjct: 1624 -AHIDSANKNRDEAIKQ 1639
Score = 61.6 bits (148), Expect = 7e-10
Identities = 60/289 (20%), Positives = 131/289 (45%), Gaps = 14/289 (4%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
K+ Q + + K+ + A+ EA + + Q +EL ++ K + L+K + L+
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATAL-QKLEEAEKAAD 121
+ + +L K + D ++++ +EL ER+ T L K+ + + D
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ +S++ K + E QL++ + + ++ +R+ ++ KL +E + E
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 182 RAELSEGKCAELEEELKT----VTNNLKSLEAQA---EKYSQKEDRYEEEIKVLSDKLKE 234
+ E E LE+++ T V + K +E E + + + +++++ LS + +E
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEE--NLSMHQ-MLDQTLLE 280
+ E++ T+L++ +DDL + H ++ NL Q DQ L E
Sbjct: 1404 KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE 1452
Score = 60.5 bits (145), Expect = 2e-09
Identities = 63/307 (20%), Positives = 137/307 (44%), Gaps = 29/307 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
++ K ++Q D LD Q+ + + + + QL E ++ K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + L A ++A + +A++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IESRAQKDEEKMEIQEIQLKEAK----HIAEDADRKYEEVARKLV-- 170
++ MK +E Q E+ E+ L+ K + D + EE ++LV
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 171 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 230
+ E + E +ER + S A + E+ +LK LEA + ++ D ++++ L
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEM-----DLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 231 KLKEA-----ETR---------AEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
++K+ +TR A+ E+ + +E + L+E++A A+ Q D+
Sbjct: 1646 QMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDE 1705
Query: 277 TLLELNN 283
E+ N
Sbjct: 1706 LADEIAN 1712
Score = 59.7 bits (143), Expect = 3e-09
Identities = 59/271 (21%), Positives = 126/271 (46%), Gaps = 27/271 (9%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAE---DRSKQLEDELVS----LQKKLKGTEDELDK 59
K++ +L EN L E ++ A + Q E EL + L+ +L + EL+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE- 914
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D + ++E E++ +A+ + + IQ +EE+L+ + +A QKL + EK
Sbjct: 915 --EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKL-QLEKV 967
Query: 120 ADES-----ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR------- 167
E+ E ++E + K ++ ++ E ++ E + + K + +A+
Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEA 1027
Query: 168 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
+ +E L R E++ + E +LE + +++ + L+AQ + + + EEE++
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+++E + A + + +LE I +L+E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQE 1118
Score = 58.9 bits (141), Expect = 5e-09
Identities = 57/271 (21%), Positives = 119/271 (43%), Gaps = 22/271 (8%)
Query: 12 KLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
KL K+ +AL+ Q + E+R K +SL KLK EDE + + E L++ +E
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQK------LSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 71 LELAEKKATDAEADVASLNRR-------IQLVEEELDRAQERLATALQKLEEAEKAADES 123
EK+ A VA + ++ ++ EE + Q+ L Q+ EE A D+
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES----DLERA 179
E+ ++R Q++ + + + +++ E +K++++ + I + + +RA
Sbjct: 1412 EK----TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA 1467
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA 239
E A E K L L+ LE +++ + + + + E E
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 240 EFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
E+ V +++ +++LE+++ ++ L +
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Score = 54.7 bits (130), Expect = 9e-08
Identities = 63/276 (22%), Positives = 121/276 (43%), Gaps = 15/276 (5%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
L K+ + EA + E+R + L+ E +KK++ EL++ E + A++K
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAE----KKKMQQNIQELEEQLEEEESARQK 961
Query: 71 LELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
L+L EK T+A+ +I L ++ A+E+ + E +E E+ +
Sbjct: 962 LQL-EKVTTEAKLKKLE-EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL--ERAEERAELSEG 188
K + K E L+E E ++ E+ RKL +DL + AE +A+++E
Sbjct: 1020 -----KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL 1074
Query: 189 KC--AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
K A+ EEEL+ ++ AQ +K E +I L + L+ AE+
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQK 1134
Query: 247 TKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
L + ++ L+ ++ + + ++ + E+N
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
Score = 54.7 bits (130), Expect = 9e-08
Identities = 65/301 (21%), Positives = 119/301 (39%), Gaps = 26/301 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE-------DE 56
++K Q L+ ++ + + K +E + K++E +L LQ K E D+
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
+ K L + L ++ K++ D ++L ++Q +E L + + KL++
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD---RKYEEVARKLVIIE 173
E + ++ E E+++ Q+ + K ED+ EEV RKL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---Q 1391
Query: 174 SDLERAEERAELSEGKCAELEEELKTVTNNLKSL----------EAQAEKYSQKEDRYEE 223
DLE +R E +LE+ + L L EK +K D+
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
E K +S K E RAE R + E L + A E+ + ++ Q E+ +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAR---EKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 284 M 284
+
Sbjct: 1509 L 1509
Score = 42.0 bits (97), Expect = 6e-04
Identities = 33/175 (18%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-DKYSEALK 65
K L++D+ N E++ A K E+ +QLE + L+ KL+ E + KY ++
Sbjct: 1753 KKANLQIDQINTDLNLERSHAQKN--ENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ K+ E++ + + + ++++ E++L ++ + E+ + AD++
Sbjct: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+K ++ + ++ EE+ + ++ + EDA + + R++ +++ L R +
Sbjct: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 30.8 bits (68), Expect = 1.4
Identities = 22/107 (20%), Positives = 46/107 (42%), Gaps = 2/107 (1%)
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ R EE E + ++ E+ N L +E + ++ + +E+++ ++ EA
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
E +LE+ DLE +V +EE H ++ ++ N
Sbjct: 900 EELRARLTAKKQELEEICHDLEARV--EEEEERCQHLQAEKKKMQQN 944
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 83.6 bits (205), Expect = 2e-16
Identities = 56/255 (21%), Positives = 129/255 (50%), Gaps = 6/255 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++LE+++ Q+K++ E++ + E ++
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHE-QEKIREQEEKRQE-EEKIR 373
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ QEK + E K E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 374 E-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E+ ++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E K E E++++ ++ E ++ +K EE++ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VTKLEKSIDDLEEKV 260
+ + E + EEK+
Sbjct: 553 MREQEVRLRQQEEKM 567
Score = 81.6 bits (200), Expect = 7e-16
Identities = 51/239 (21%), Positives = 113/239 (47%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K K+ E + EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E E EE++ + E + ++ +K R EE+++ +L++ E + +
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 81.3 bits (199), Expect = 9e-16
Identities = 50/251 (19%), Positives = 124/251 (49%), Gaps = 4/251 (1%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL----ELAE 75
++ ++ E + E++ ++ E+ + ++K++ E+ + + E +++ +EK+ ++ E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
++ E + + Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 136 KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEE 195
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EGK E E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 196 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
+++ ++ E + + +K EE+I+ + ++E E + E + + E+ + +
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 256 LEEKVAHAKEE 266
EEK+ +E+
Sbjct: 542 QEEKMRRQEEK 552
Score = 80.1 bits (196), Expect = 2e-15
Identities = 63/281 (22%), Positives = 134/281 (47%), Gaps = 19/281 (6%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEDELVSLQKKLKGTEDELDK 59
+ ++ K+Q ++++ +R Q + +K E++ ++ E+++ ++K++ E+++ +
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + +EK+ E+ + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
E E M E + ++ EEK+ QE ++E + + + K E ++ E + R
Sbjct: 379 -QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 180 EERAELSEGKCAELEEELKTVTNNL------------KSLEAQAEKYSQKED--RYEEEI 225
EE+ E K E EE+++ + K E +A+ Q+E R EE+I
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 226 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ K++E E + E + + E+ + + EEK+ +E+
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Score = 76.6 bits (187), Expect = 2e-14
Identities = 64/305 (20%), Positives = 134/305 (43%), Gaps = 49/305 (16%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 271
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDR----------- 101
+E + ++ + +EK+ E+K + E + +I+ EE++ R
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 102 ----------AQERLATALQKLEEAEKAADESERGMKVIESRAQ-----------KDEEK 140
+E++ +K+ E EK ++ E+ + + R Q + EEK
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
+ QE +++E + + ++ + K E K+ E +++ EE+ E K E E++++
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++ E ++ +K E ++ K++E E + E + + EK I + EEK+
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 261 AHAKE 265
+E
Sbjct: 512 REQEE 516
Score = 68.9 bits (167), Expect = 5e-12
Identities = 63/253 (24%), Positives = 119/253 (47%), Gaps = 19/253 (7%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIES 132
++ + +V L R+++ L +++L + L LQ + +A E +
Sbjct: 225 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN- 283
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAE 192
Q+ EEKM QE +++E + ++ + K E K+ E + EE+ E E
Sbjct: 284 --QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 193 LEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKS 252
EE+++ + + + EK ++E++ +EE +K++E E R E E + + E+
Sbjct: 342 KEEKIRELEEKMH----EQEKIREQEEKRQEE-----EKIREQEKRQE-QEAKMWRQEEK 391
Query: 253 IDDLEEKVAHAKE 265
I + EEK+ +E
Sbjct: 392 IREQEEKIREQEE 404
Score = 67.0 bits (162), Expect = 2e-11
Identities = 39/201 (19%), Positives = 100/201 (49%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
+K ++ ++ EA E++ ++ E+++ ++ ++ E+++ + E + + +E+++
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
E+K E + ++I+ EE++ +E + +K+ E E E E M+ E +
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
++ EEK+ QE +++E + + + +E K+ E + EE+ + E K
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Query: 194 EEELKTVTNNLKSLEAQAEKY 214
EE+++ L+ E + +++
Sbjct: 550 EEKMREQEVRLRQQEEKMQEH 570
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 83.6 bits (205), Expect = 2e-16
Identities = 59/271 (21%), Positives = 128/271 (47%), Gaps = 9/271 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE---- 117
E +++ +EK+ E+K E ++ + ++ EEE + QE + +K+ E E
Sbjct: 484 EKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 118 --KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
+ E E ++ E + + EEKM QE +++E + + K E K+ E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ EE + E K E EE++ ++ E + + +K E++I+ +K++E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E + E + + E+ + + EEK+ +E+
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/249 (20%), Positives = 121/249 (48%), Gaps = 17/249 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED------ 55
+ I+++ + ++ +E + E+ +K E+ +Q ++E+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E ++ +EK+ E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E E M E + + EEKM+ QE +++ + + ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV--LSDKLK 233
++ EE+ E K E EE+++ E + + Q+E +E+E+++ +K++
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQ---------EQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Query: 234 EAETRAEFA 242
E + E A
Sbjct: 715 EHQEHLEAA 723
Score = 77.8 bits (190), Expect = 1e-14
Identities = 51/256 (19%), Positives = 125/256 (48%), Gaps = 5/256 (1%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS----EALKDAQE 69
+K ++ ++ EA E++ ++ E+++ ++K+ E+++ + E + QE
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 70 KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
++ E+K + E ++ +I EE++ + +E++ +K+ + E+ E E +
Sbjct: 524 EMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 130 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGK 189
E + ++ EEK+ QE +++E + + ++ + K E K+ E ++ EE+ E K
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
E E++++ ++ E ++ +K EE++ +K++E E + E + +
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 250 EKSIDDLEEKVAHAKE 265
E + EEK+ +E
Sbjct: 703 EVRLRQQEEKMQEHQE 718
Score = 72.8 bits (177), Expect = 3e-13
Identities = 59/285 (20%), Positives = 135/285 (47%), Gaps = 13/285 (4%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ ++ E + Q++E+ E ++ Q +EAK + + K E K+ E + R EE
Sbjct: 449 EQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKIREQEEKMWRQEE 505
Query: 182 RA-ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV---------LSDK 231
+ E + + E +E + + + + Q E + QKE +E+E K+ +K
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ + E + E V + E+ I + EEK+ +E+ +M +
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Score = 71.6 bits (174), Expect = 7e-13
Identities = 51/255 (20%), Positives = 123/255 (48%), Gaps = 9/255 (3%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ ++ E + E++ ++ E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 80 DAEADVASLNRRIQLVE-----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
+ E + L ++ E EE + +E++ +K +E E E ++ E +
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKI 493
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEV---ARKLVIIESDLERAEERAELSEGKCA 191
++ EEKM QE ++ E + I E+ R+ +E + + + ++ R +E+ E K
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 192 ELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
+ EE++ + E + + +K R EE+I+ +K++E E + E + E+
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 252 SIDDLEEKVAHAKEE 266
+ + EEK+ +E+
Sbjct: 614 KMGEQEEKMCEQEEK 628
Score = 65.5 bits (158), Expect = 5e-11
Identities = 64/275 (23%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL----VIIESDLER 178
E M E + ++ EE M +E +++ + + + + K E+ K+ I E + +R
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 179 AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE + K E E ++ ++ E + + +K R EE+I +K++E E R
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-QEKIREEEKR 519
Query: 239 AEFAERSVTKLEKSIDDLEE-----KVAHAKEENL 268
E + + + E+ I + EE + H +EE +
Sbjct: 520 QE--QEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Score = 60.1 bits (144), Expect = 2e-09
Identities = 67/272 (24%), Positives = 121/272 (44%), Gaps = 34/272 (12%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQ------------ERLATALQ--------KLEEAE 117
++ + +V L R +L+RA+ + L LQ ++EE E
Sbjct: 298 KSEIQLNVKELKR-------KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 350
Query: 118 ---KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + E M E + Q+ EEK++ QE +++E + + + K + E
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+ R EE E K EE + ++ LE + + Q++ R +EE + +K++E
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE--EKMHEQEKIREQEEKRQEEEKIRE 468
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E R E E + + E+ I + EEK+ +E+
Sbjct: 469 QEKRQE-QEAKMWRQEEKIREQEEKIREQEEK 499
Score = 54.3 bits (129), Expect = 1e-07
Identities = 60/252 (23%), Positives = 119/252 (47%), Gaps = 22/252 (8%)
Query: 37 KQLEDELVSLQKKLKGT---EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR-RI 92
KQLE E L +L + EL++ A+ ++K + ++ T E D SL R
Sbjct: 215 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK-ERDALSLELYRN 273
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-EA 151
+ +EEL +L LQ +E +++SE + V E + + + K+ + + QL+ EA
Sbjct: 274 TITDEELKEKNAKLQEKLQLVE-----SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 328
Query: 152 KHIAEDADRKYEEVARKL--VIIESDL-----ERAEERAELSEGKCAELEEELKTVTNNL 204
H+ ++ + V+ KL + E++L ++ EE+ E K E EE+++ +
Sbjct: 329 DHLGKEL----QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 205 KSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAK 264
+ E + + +K R EE + +K++ E E + + E+ + + EEK+ +
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 265 EENLSMHQMLDQ 276
E+ ++ +Q
Sbjct: 445 EKMHEQEKIREQ 456
Score = 35.8 bits (81), Expect = 0.044
Identities = 21/106 (19%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KMQ + ++ + E + E++ ++ E+ + ++K+ E+++ + E +
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
++ +EK+ E+K + E R++ EE++ QE L A+
Sbjct: 686 QEQEEKMRRQEEKMWEQEV-------RLRQQEEKMQEHQEHLEAAI 724
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 80.5 bits (197), Expect = 2e-15
Identities = 78/323 (24%), Positives = 152/323 (47%), Gaps = 67/323 (20%)
Query: 5 KKKMQMLKLDKENALD-------RAEQAEADKKAAE-DRSKQLEDELVSLQK-----KLK 51
K+K +M+K +++ + AE+ EA ++ E DR ++L+DE+V Q KL
Sbjct: 170 KRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLY 229
Query: 52 GTEDELDKYSEALKDAQEKLELAEKKATDAE-------ADVASLNRRIQLVEEELD---- 100
E E++K ++ L +++E +K+ E ++ + R Q +E+E+
Sbjct: 230 HNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDS 289
Query: 101 ----------RAQERLATALQKLEEAEKA--------------ADESERGMKVIESRAQK 136
+A+E + ++KLE A+K+ DE E+ M +E Q+
Sbjct: 290 ELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQE 349
Query: 137 DEEKME-----------IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
EE+ME ++E Q+K+ + E+A ++ +A++L D + ++R +L
Sbjct: 350 FEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL 409
Query: 186 SEGKCAELE----EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
E K E E ++L+ + N K +E + E+Y + EE K L +L E E
Sbjct: 410 EERKKVETEAKIKQKLREIEENQKRIE-KLEEYITTSKQSLEEQKKLEGELTE---EVEM 465
Query: 242 AERSVTKLEKSIDDLEEKVAHAK 264
A+R + ++ K ++ + E++ A+
Sbjct: 466 AKRRIDEINKELNQVMEQLGDAR 488
Score = 60.1 bits (144), Expect = 2e-09
Identities = 70/288 (24%), Positives = 131/288 (45%), Gaps = 36/288 (12%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----- 55
MD ++K+M L E A E+ ++ ++ R LE+ V +LK
Sbjct: 333 MDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAAT 388
Query: 56 ---ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
EL+K++ K Q++L+L E+K + EA + R I+ ++ +++ +E + T+ Q
Sbjct: 389 LAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQS 448
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEI--QLKEAKHIAEDADRKYEEVARKLV 170
LEE +K E E +V ++ + DE E+ ++ QL +A+ +++ R+ RK
Sbjct: 449 LEEQKKL--EGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQ----QRKAE 502
Query: 171 IIESDLERAEERAELSE--GKCAELEEE-----LKTVTNNLKSLEAQAEKYSQ------K 217
I+ES ++R + C +++ K + N+ ++ +EK + K
Sbjct: 503 IMES-IKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIK 561
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
E R E E + D L+ T + E KL ID + + H K+
Sbjct: 562 EQRGEPETFLPLDYLEVKPTDEKLRELKGAKL--VIDVIRYEPPHIKK 607
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/252 (25%), Positives = 113/252 (44%), Gaps = 18/252 (7%)
Query: 35 RSKQLEDELVSLQKKL-KGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQ 93
RS +L E +K++ K ED Y A E+ E ++K EAD R Q
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKE---EAD------RYQ 210
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+++E+ RAQ +L L KL E ++ + + +KD+++M+ E +LKE K
Sbjct: 211 RLKDEVVRAQVQLQ--LFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKK 268
Query: 154 IAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEK 213
R+ +++ ++ I E D E ++R + + K ++K + KSL+ +
Sbjct: 269 ELGKMMREQQQIEKE--IKEKDSELNQKRPQYIKAK-ENTSHKIKKLEAAKKSLQNAQKH 325
Query: 214 YSQKE---DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
Y +++ D E+E+ + +E E R E +S + ++ +K KEE
Sbjct: 326 YKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKR 385
Query: 271 HQMLDQTLLELN 282
L Q L + N
Sbjct: 386 AATLAQELEKFN 397
Score = 43.5 bits (101), Expect = 2e-04
Identities = 36/230 (15%), Positives = 103/230 (44%), Gaps = 6/230 (2%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
E K+ E+E+ L+K+ + +D+ L+D + + + + D ++ + +++
Sbjct: 839 EQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKL 898
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
+E+ Q+ + KLE+ + K+ + + + M+ +I +E
Sbjct: 899 GGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMD--DISQEEGS 956
Query: 153 HIAEDA---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
ED+ ++ + + +IE D E + ++ + E+++E+ T+ L ++
Sbjct: 957 SQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAE-EEIKQEMNTLQQKLNEQQS 1015
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
++ + + E+++ + DK +E E A + K +++ + ++++
Sbjct: 1016 VLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 40.8 bits (94), Expect = 0.001
Identities = 48/227 (21%), Positives = 101/227 (44%), Gaps = 21/227 (9%)
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
+K + LK+ +E+L K+ A+ A L + V+ + Q RL + LE+ +
Sbjct: 668 EKAVDKLKEKKERLTEELKEQMKAKRKEAELRQ----VQSQAHGLQMRLKYSQSDLEQTK 723
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
R + + K E ++ ++ + K I + +R+ +++ K+ +E ++
Sbjct: 724 T------RHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVF 777
Query: 178 RAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
E E+ E EEE N + + E ++ R ++ ++LKE +
Sbjct: 778 E-EFCREIGVRNIREFEEEKVKRQNEIAKKRLEFEN---QKTRLGIQLDFEKNQLKEDQD 833
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
+ E++V K E I+ L+ KEE M +++D+T+ +L ++
Sbjct: 834 KVHMWEQTVKKDENEIEKLK------KEEQRHM-KIIDETMAQLQDL 873
Score = 38.9 bits (89), Expect = 0.005
Identities = 41/192 (21%), Positives = 88/192 (45%), Gaps = 22/192 (11%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
+++SK LE EL + ++ + + +KD +EK+ E + + +
Sbjct: 732 QEKSK-LESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIR 790
Query: 93 QLVEEELDR----AQERLATALQK------LEEAEKAADESERGMKVIESRAQKDEEKME 142
+ EE++ R A++RL QK L+ + E + + + E +KDE E
Sbjct: 791 EFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDEN--E 848
Query: 143 IQEIQLKEAKH-------IAEDADRKYEEVARKLVIIESDLERAEERAEL--SEGKCAEL 193
I++++ +E +H +A+ D K + +A+K + + + E E R +L + + L
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 194 EEELKTVTNNLK 205
++E+ + L+
Sbjct: 909 QKEVTAIETKLE 920
Score = 31.6 bits (70), Expect = 0.83
Identities = 47/247 (19%), Positives = 103/247 (41%), Gaps = 39/247 (15%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++ M+++ D Q A K D++ ++E+ ++KKL G E +
Sbjct: 857 QRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEE----IRKKLGGANKE-------M 905
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Q+++ E K +D +L + ++ + +L ++ + Q EE ++S
Sbjct: 906 THLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQ--EEGSSQGEDSV 963
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
G + I S + E +EI L E DL+ A+ E
Sbjct: 964 SGSQRISSIYAR-EALIEIDYGDLCE------------------------DLKDAQAEEE 998
Query: 185 LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
+ + + L+++L + L+ + A K +K + ++ + SD+ + A RA+ A++
Sbjct: 999 IKQ-EMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQ 1057
Query: 245 SVTKLEK 251
+ +++K
Sbjct: 1058 AFEQIKK 1064
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/118 (20%), Positives = 54/118 (45%), Gaps = 22/118 (18%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+ +I + ++++D + + + A+A++ +++ E+ +LQ+KL + L +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEE--------EIKQEMNTLQQKLNEQQSVLQRI 1020
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ A EKLE S+ + Q +E + A++R A Q E+ +K
Sbjct: 1021 AAPNMKAMEKLE--------------SVRDKFQETSDEFEAARKRAKKAKQAFEQIKK 1064
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 80.1 bits (196), Expect = 2e-15
Identities = 76/312 (24%), Positives = 143/312 (45%), Gaps = 42/312 (13%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 647
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 648 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 707
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 708 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
E ++ D D+K E+ R++ + + + ++ + K A++ EE + +NL
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 826
Query: 210 Q-AEKYSQKEDRYEEEIKVLSDKLK---EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
Q + +K+DR EE + L + ++ E E E + T EK +++L + K+
Sbjct: 827 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 886
Query: 266 ENLSMHQMLDQT 277
E SM L T
Sbjct: 887 ELESMKAKLSST 898
Score = 72.0 bits (175), Expect = 6e-13
Identities = 73/341 (21%), Positives = 151/341 (44%), Gaps = 62/341 (18%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A++ K++ L ++ E + A E R+ L+ E+ +L+ +L+ E L+K ++
Sbjct: 484 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 63 ALKD-AQEK-------------LELAEKKATDAEADVASLNRRIQLVEEELDRAQERLA- 107
++D A+EK L++ E+K + + +L +++ E+++ +ER+
Sbjct: 544 QIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKS 603
Query: 108 ---------TALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAED 157
TAL LEE A E ER ++ ++ + +DE EK E + K+ K + E
Sbjct: 604 LQADTTNTDTALTTLEE---ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK 660
Query: 158 ADRKYEEVARKLVII-----------------ESDLERAEERAELSEGKCAELEEELK-- 198
+++ K + +S L+ E E + +C ++E +LK
Sbjct: 661 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA 720
Query: 199 -----------TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
+++ ++ LE + +Y + + + E+ L + LKE E ++ +
Sbjct: 721 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 780
Query: 248 KLEKSIDDLEEKVAHAKE----ENLSMHQMLDQTLLELNNM 284
+LE+ + D +KVA+ K E QML++ +N+
Sbjct: 781 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNL 821
Score = 69.3 bits (168), Expect = 4e-12
Identities = 64/282 (22%), Positives = 134/282 (47%), Gaps = 22/282 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 705 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + +++ A Q LEEA + D
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRRED 819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+E+ ++ E + K + ++ L +L +L A+ K+ EE +++ + L
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH------LEEVLEMKQEALLA 933
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
A + + A ++ +L S +E+VA K E + Q L Q
Sbjct: 934 AISEKD-ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 974
Score = 63.5 bits (153), Expect = 2e-10
Identities = 60/305 (19%), Positives = 140/305 (45%), Gaps = 24/305 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDK 59
++IKK ++ML+ +A E E ++ AE LE L +K+ +E+ +
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR 366
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D+ K + + ++ ++S+ R ++ +EEE+ + A + ++ EE K
Sbjct: 367 RFENAPDSA-KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQ 425
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+ K ++++ ++ +E++ +E Q +E K A + +V ++L +++L
Sbjct: 426 MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLAL 485
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED----RYEEEIKVLSDKLKEA 235
+ + E + ++ ++ ++ + +L + E +A + D R EE+ +L+ K K+
Sbjct: 486 QTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI 545
Query: 236 ETRAE-----------------FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+ AE ER V L+K I++L+E++ +++ S+ + +
Sbjct: 546 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 605
Query: 279 LELNN 283
+ N
Sbjct: 606 ADTTN 610
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/230 (23%), Positives = 112/230 (48%), Gaps = 41/230 (17%)
Query: 6 KKMQMLK----LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
KK+ LK ++K+ + E+A + D S+QL+D SL+KK +D +++
Sbjct: 791 KKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKK----DDRIEELE 843
Query: 62 EALKD-----AQEKLELAEKKA--TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
EAL++ A+ ++ LA++++ T+AE V L ++ V++EL+ + +L++ Q L
Sbjct: 844 EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA 903
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E E + RA++ + E+ +++K+ +A +++ + L+ + S
Sbjct: 904 EKE---------THLTNLRAERRKHLEEV--LEMKQEALLAAISEK---DANIALLELSS 949
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
++ +E + + L ++LK T N L A D YE++
Sbjct: 950 SKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA---------DNYEDD 990
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 80.1 bits (196), Expect = 2e-15
Identities = 76/312 (24%), Positives = 143/312 (45%), Gaps = 42/312 (13%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 619
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 680 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
E ++ D D+K E+ R++ + + + ++ + K A++ EE + +NL
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 798
Query: 210 Q-AEKYSQKEDRYEEEIKVLSDKLK---EAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
Q + +K+DR EE + L + ++ E E E + T EK +++L + K+
Sbjct: 799 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 858
Query: 266 ENLSMHQMLDQT 277
E SM L T
Sbjct: 859 ELESMKAKLSST 870
Score = 72.0 bits (175), Expect = 6e-13
Identities = 73/341 (21%), Positives = 151/341 (44%), Gaps = 62/341 (18%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A++ K++ L ++ E + A E R+ L+ E+ +L+ +L+ E L+K ++
Sbjct: 456 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 515
Query: 63 ALKD-AQEK-------------LELAEKKATDAEADVASLNRRIQLVEEELDRAQERLA- 107
++D A+EK L++ E+K + + +L +++ E+++ +ER+
Sbjct: 516 QIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKS 575
Query: 108 ---------TALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAED 157
TAL LEE A E ER ++ ++ + +DE EK E + K+ K + E
Sbjct: 576 LQADTTNTDTALTTLEE---ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK 632
Query: 158 ADRKYEEVARKLVII-----------------ESDLERAEERAELSEGKCAELEEELK-- 198
+++ K + +S L+ E E + +C ++E +LK
Sbjct: 633 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA 692
Query: 199 -----------TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
+++ ++ LE + +Y + + + E+ L + LKE E ++ +
Sbjct: 693 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 752
Query: 248 KLEKSIDDLEEKVAHAKE----ENLSMHQMLDQTLLELNNM 284
+LE+ + D +KVA+ K E QML++ +N+
Sbjct: 753 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNL 793
Score = 69.3 bits (168), Expect = 4e-12
Identities = 64/282 (22%), Positives = 134/282 (47%), Gaps = 22/282 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 677 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + +++ A Q LEEA + D
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRRED 791
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 792 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 851
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+E+ ++ E + K + ++ L +L +L A+ K+ EE +++ + L
Sbjct: 852 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH------LEEVLEMKQEALLA 905
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
A + + A ++ +L S +E+VA K E + Q L Q
Sbjct: 906 AISEKD-ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 946
Score = 59.7 bits (143), Expect = 3e-09
Identities = 51/284 (17%), Positives = 130/284 (45%), Gaps = 10/284 (3%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDK 59
++IKK ++ML+ +A E E ++ AE LE L +K+ +E+ +
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR 366
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E D+ K + + ++ ++S+ R ++ +EEE+ + A + ++ EE K
Sbjct: 367 RFENAPDSA-KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQ 425
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
+ K ++++ + ++++ ++ +L + E ++ + + + +++ L
Sbjct: 426 MEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAK 485
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA 239
E+RA + L+ E+ + L+ E K +++ EE + ++ + +
Sbjct: 486 EQRAAI-------LQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML 538
Query: 240 EFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ ER V L+K I++L+E++ +++ S+ + + + N
Sbjct: 539 DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 582
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/230 (23%), Positives = 112/230 (48%), Gaps = 41/230 (17%)
Query: 6 KKMQMLK----LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
KK+ LK ++K+ + E+A + D S+QL+D SL+KK +D +++
Sbjct: 763 KKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD---SLRKK----DDRIEELE 815
Query: 62 EALKD-----AQEKLELAEKKA--TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
EAL++ A+ ++ LA++++ T+AE V L ++ V++EL+ + +L++ Q L
Sbjct: 816 EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA 875
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E E + RA++ + E+ +++K+ +A +++ + L+ + S
Sbjct: 876 EKE---------THLTNLRAERRKHLEEV--LEMKQEALLAAISEK---DANIALLELSS 921
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
++ +E + + L ++LK T N L A D YE++
Sbjct: 922 SKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA---------DNYEDD 962
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 79.7 bits (195), Expect = 3e-15
Identities = 56/292 (19%), Positives = 139/292 (47%), Gaps = 20/292 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 EALKDAQEKLELAEKKATDAEADV---------------ASLNRRIQLV--EEELDRAQE 104
E +++ +EK+ EKK E + + R+ + + +EE+ R +E
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
++ +K+ + E+ E ++ E + ++ EEKM QE +++E + + + ++ +E+
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
+ + E + E++ E K E EE++ ++ E + ++ +K + EE+
Sbjct: 557 ---EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
I+ +K++E E + E + + E+ + EEK+ +E+ + + +
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Score = 75.1 bits (183), Expect = 7e-14
Identities = 51/238 (21%), Positives = 119/238 (50%), Gaps = 4/238 (1%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA---DVASLN 89
+++ + E+++ ++K+ E+++ + E +++ +EK+ E+K + E + ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 90 RRIQLVEEELDRAQE-RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
+ ++ EEE + QE ++ +K+ E E+ E ++ E + Q+ EEKM QE ++
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE 208
+E + ++ + K E K+ E + EE+ E K E EE+++ + E
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 209 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ + +K EE+I+ + ++E E + E + + E+ + + EEK+ +E+
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 75.1 bits (183), Expect = 7e-14
Identities = 54/249 (21%), Positives = 119/249 (47%), Gaps = 12/249 (4%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEK------ 76
EQ E +K E +Q E+++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCA 191
+ Q+ EEK+ QE +++E + + ++ + K E K+ E ++ EE E K
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 ELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
E E++++ ++ E ++ +K EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 SIDDLEEKV 260
+ EEK+
Sbjct: 739 RLRQQEEKM 747
Score = 74.7 bits (182), Expect = 9e-14
Identities = 61/283 (21%), Positives = 135/283 (47%), Gaps = 19/283 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ ++ + E+ +K E+ +Q ++E+ ++K+ ++E+ +
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH-EQEEIWRQK 495
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQ------KLEE 115
E + + +EK+ E+K E + +I+ EE++ R +E++ + K+ E
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 116 AEKAADESERG-----MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 170
EK +E +R M E + ++ EEK+ QE +++E + ++ + K + K+
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 171 IIESDLERAEERAELSEGKCAELEE-----ELKTVTNNLKSLEAQAEKYSQKEDRY--EE 223
E ++ EE+ E K E EE E K K E + + Q+E + EE
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+I+ K++E E + E + + E+ + + EEK+ +E+
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Score = 71.6 bits (174), Expect = 7e-13
Identities = 50/236 (21%), Positives = 114/236 (48%), Gaps = 4/236 (1%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ +E + E+ ++ + K E E + ++K + ED++ +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K + E ++ EE++ +E++ +K+ E E+
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E + E + + EEKM QE +++E + + K E +K+ E + EE
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR-YEEEIKVLSDKLKEAE 236
+ E K E EE++ + ++ Q EK ++E++ +E+E+++ + K E
Sbjct: 697 MMQEQEEKMWEQEEKM---CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 69.3 bits (168), Expect = 4e-12
Identities = 55/278 (19%), Positives = 133/278 (47%), Gaps = 31/278 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++ E+ + ++K++ E+++ + E ++
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIR 407
Query: 66 DAQEKLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ +EK + EK K + EA + +I+ EE++ ++++ +K+ E EK
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+E +R +++E+M QE ++ E + I ++ +E+ E + + E
Sbjct: 468 EEEKR----------QEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--------EEKIRKQE 509
Query: 181 ERAELSEGKCAELEEELKTVTNNL----KSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
E+ E K E EE+++ + + + Q E + ++E +E+E +K +E E
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ E + + E+ + EEK+ +E+ + +
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Score = 68.2 bits (165), Expect = 8e-12
Identities = 56/268 (20%), Positives = 124/268 (46%), Gaps = 6/268 (2%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ +E +K E+ +I+E + K + K +E K+ E + EE
Sbjct: 388 EKEEKIRELE---EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 182 RAELSEGKCAELEEEL--KTVTNNLKSLEAQAEKYSQKEDRYE-EEIKVLSDKLKEAETR 238
+ E K EE++ + + + Q E + Q+E +E EEI +K+ E E +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E V + E+ I + EEK+ +E+
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 66.6 bits (161), Expect = 2e-11
Identities = 64/285 (22%), Positives = 131/285 (45%), Gaps = 29/285 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 283
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+E + ++ + +EK+ E+K + E + +I+ EE++ +E++ +
Sbjct: 284 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL--- 169
+ E E+ E M E + ++ EE M +E +++ + + + + K E+ K+
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Query: 170 -VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
I E + +R EE + K E E ++ ++ E + + +K R EE+I
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE- 462
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEE-----KVAHAKEENL 268
+K++E E R E + + + E+ I + EE + H +EE +
Sbjct: 463 QEKIREEEKRQE--QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Score = 63.9 bits (154), Expect = 2e-10
Identities = 45/212 (21%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Query: 12 KLDKENALDRAEQA--EADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE 69
K+ ++ + R E+ E +K E++ ++ ED++ ++K++ E+++ + E +++ +E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 70 KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
K + E+K E + +IQ EE++ +E++ + +E E+ E E M
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 130 IESRAQ-------KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E + Q + EEK+ QE +++E + + + +E K+ E + EE+
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Query: 183 AELSEGKCAELEEELKTVTNNLKSLEAQAEKY 214
+ E K EE++ L+ E + +++
Sbjct: 719 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 63.2 bits (152), Expect = 3e-10
Identities = 61/278 (21%), Positives = 118/278 (42%), Gaps = 13/278 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K ++QM ++A+ + E D + S + EL + + + D+Y E L
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 198
Query: 65 KDAQE--KLELAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ LEL TD E A L ++QLVE E Q + +KLE A+
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIESDLER 178
+ + +A+ D E+Q + K + E+ +R ++ K+ E ++
Sbjct: 259 PQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 179 AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE+ + E K E EE+++ ++ E + +K R EE + +K++ E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + + E+ + + EEK+ +E+ ++ +Q
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Score = 59.3 bits (142), Expect = 4e-09
Identities = 57/271 (21%), Positives = 125/271 (46%), Gaps = 30/271 (11%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ + E + E+ + E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 388 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA---RKLVIIESDLERAEERAELSEGKC 190
++ E+KM QE ++ E + I E+ R+ +E + + + ++ R +E+ E K
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDR-YEEEIKVL--------------SDKLKEA 235
+ EE+ V + + Q EK ++E++ + +E K+ +K+ E
Sbjct: 506 RKQEEK---VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E R E E + + E+ I + EEKV +E+
Sbjct: 563 EKRQE-QEDKMWRQEEKIREQEEKVWRQEEK 592
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 79.7 bits (195), Expect = 3e-15
Identities = 61/280 (21%), Positives = 132/280 (47%), Gaps = 16/280 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ +++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E + + + ++ EEE + QE + +K+ E E+
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 122 ESER-----GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
+ E+ ++ E + + EEKM QE +++E + + K E K+ E +
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 177 ERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
EE + E K E EE+++ + + Q EK ++E E+I+ +K++E E
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQ----EQEKMRRQEEKIREQE----EKIREQKEKIREQE 591
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ E + + E+ + + EEK+ +E+ + + +
Sbjct: 592 EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Score = 73.2 bits (178), Expect = 2e-13
Identities = 60/265 (22%), Positives = 131/265 (49%), Gaps = 20/265 (7%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++LE+ + ++K++ E+++ +
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRLEEMMWEKEEKIRELEEKMHE------ 388
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ E+K + E R+ Q E ++ R +E++ +K+ E EK E
Sbjct: 389 --QEKIREQEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 126 GM----KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ K+ E ++++E+M QE +++E + I ++ +E+ K+ E + R EE
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQEE 502
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ E K E EE++ ++ E + + +K EE ++ +K+ E E + +
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 242 AERSVTKLEKSIDDLEEKVAHAKEE 266
E+ + + E+ I + EEK+ KE+
Sbjct: 563 QEK-MRRQEEKIREQEEKIREQKEK 586
Score = 71.6 bits (174), Expect = 7e-13
Identities = 57/264 (21%), Positives = 126/264 (47%), Gaps = 24/264 (9%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ ++ + E+ +K E+ +Q ++E+ ++K++ ++E+ +
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 481
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + + QEK+ E+K E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 482 EKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E M+ E + + EEKM+ QE ++ + I E ++ E+ + + EE
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ--------KEKIREQEE 592
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ E K E EE ++ E + + + Q+E E+E +K++E E +
Sbjct: 593 KIWEQEEKIREQEEMMQ---------EQEEKMWEQEEKMCEQE-----EKMQEQEEKMRR 638
Query: 242 AERSVTKLEKSIDDLEEKVAHAKE 265
E + + E + EEK+ +E
Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 71.2 bits (173), Expect = 9e-13
Identities = 54/284 (19%), Positives = 135/284 (47%), Gaps = 12/284 (4%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 122 ESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
E E+ + E R + +++EK + QE ++ + + + K E +K+ E E
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---E 444
Query: 178 RAEERAELSEGKCAELEEELKTVTNNLKSLE---AQAEKYSQKED--RYEEEIKVLSDKL 232
+ E+ ++ E + + +EE+ ++ E Q EK ++E + EE++ +K+
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ E + E + + E+ I + EEK+ +E+ +M+ +
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/267 (20%), Positives = 130/267 (48%), Gaps = 14/267 (5%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ ++ E + E++ ++ E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 374 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRK-YEEVARKLVIIESDLERAEERAELSEGKCAE 192
++ E+KM QE ++ E + I E+ R+ EE+ R+ I E ++ ++ E +
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 193 LEEELKTVTNNLKSLEAQAEKYSQKED---RYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
+EE V + + Q EK ++E+ R EE+I+ +K++E E + E + +
Sbjct: 492 KQEE--KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 250 EKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E+ + + EEK+ ++ ++ +Q
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/242 (22%), Positives = 116/242 (47%), Gaps = 14/242 (5%)
Query: 5 KKKM--QMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
+KKM Q K+ ++ + E+ + ++ K E E + QK+ ++++ K E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+ +EK+ E+K + E + +I+ EE++ +E++ + ++E E+ E
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M+ + + ++ EEK+ QE +++E K + + K E K+ E ++ EE+
Sbjct: 556 QEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 183 AELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV--LSDKLKEAETRAE 240
E K E EE+++ E + + Q+E +E+E+++ +K++E + E
Sbjct: 615 MWEQEEKMCEQEEKMQ---------EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Query: 241 FA 242
A
Sbjct: 666 AA 667
Score = 64.3 bits (155), Expect = 1e-10
Identities = 61/260 (23%), Positives = 118/260 (45%), Gaps = 11/260 (4%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL----VIIESDLER 178
E M E + ++ EE M +E +++ + + + + K E+ K+ I E + +R
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399
Query: 179 AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE + K E E ++ ++ E + + +K R EE+I +K++E E R
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKR 458
Query: 239 AEFAERSVTKLEKSIDDLEE 258
E + + + E+ I + EE
Sbjct: 459 QE--QEEMWRQEEKIREQEE 476
Score = 48.5 bits (114), Expect = 7e-06
Identities = 61/278 (21%), Positives = 115/278 (41%), Gaps = 34/278 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K ++QM ++A+ + E D + S + EL + + + D+Y E L
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 198
Query: 65 KDAQE--KLELAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ LEL TD E A L ++QLVE E Q + +KLE A+
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVIIESDLER 178
+ + +A+ D E+Q + K + E+ +R ++ K+ E ++
Sbjct: 259 PQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 179 AEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
EE+ + E K E EE+++ Q EK ++E+ E KE + R
Sbjct: 312 WEEKIQEQEEKIREQEEKIRE----------QEEKMRRQEEMMWE---------KEEKMR 352
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ E + + E+ + LEE + +E+ + + + +
Sbjct: 353 RQ--EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Score = 46.6 bits (109), Expect = 2e-05
Identities = 55/271 (20%), Positives = 117/271 (43%), Gaps = 19/271 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D KKK+ + E ++KA+ + L EL + ++ + +
Sbjct: 84 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQ 143
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
AL +Q ++ E +A D + + + +E+ L + A + +EE K D
Sbjct: 144 MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERD 203
Query: 122 ----ESERGMKVIESRAQKD---EEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E R E +K+ +EK+++ E + E + ++ RK E KL++ +
Sbjct: 204 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA--KLLLPQQ 261
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
L+ + L +EL++V+ L++ + E +++ + EE++ +K++E
Sbjct: 262 QLQAEADH----------LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
E + + E + + E+ I + EEK+ +E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
Score = 33.9 bits (76), Expect = 0.17
Identities = 18/108 (16%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQL---EDELVSLQKKLKGTEDELDKYSE 62
++ + ++ +E ++ E+ K+ ++ +++ E+++ ++ ++ E+++ + E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
+ + +EK++ E+K E + R++ EE++ QE L A+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 77.4 bits (189), Expect = 1e-14
Identities = 67/272 (24%), Positives = 123/272 (45%), Gaps = 15/272 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K+++ L+ ++ E+A A + +SK+ E +L SL+ ++ ++EL
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700
Query: 62 EALKDA-QEKLELAEKKATDAEADVASLNR------RIQLVEEELDRAQERLATALQKLE 114
A + A QE+ ELA++ A A L+ RI +EEEL+ Q + +
Sbjct: 1701 RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFR 1760
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV-IIE 173
+ D + S AQK + + E Q KE K ++ + + + + +E
Sbjct: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALE 1820
Query: 174 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEI-------K 226
+ + + EE+ E + A + ++ LK + Q E + D+Y+E++ K
Sbjct: 1821 AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 227 VLSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
L +L+EAE A A S KL++ +DD E
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/253 (24%), Positives = 115/253 (45%), Gaps = 15/253 (5%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA-LKDAQEKLELA---EKKA 78
E +A + AE + + L +EL +L+ +L+ T D E K QE EL E++
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 79 TDAEADVASLNRR----IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
+ EA + + +R ++ + E+L++A+ A + + E E +KV++
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGK----- 189
+ E K + + Q++E + DR E+A K ++++L+ E +E K
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 190 --CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
A LE +L+ L+ Q S + + EEE L ++ +E E + E+ V
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 248 KLEKSIDDLEEKV 260
L+ + D ++KV
Sbjct: 1368 ALQSQLADTKKKV 1380
Score = 66.6 bits (161), Expect = 2e-11
Identities = 73/306 (23%), Positives = 144/306 (47%), Gaps = 41/306 (13%)
Query: 4 IKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
++ MQ +K E L R EQ E K+ + ++LE EL EDE + +
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL----------EDERKQRAL 1614
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
A+ +++K+E+ K D EA + + N+ V ++L + Q ++ ++LEEA + DE
Sbjct: 1615 AVA-SKKKMEIDLK---DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDE 1670
Query: 123 SERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
K E + + E E +++QE +L ++ A+++ +E+A ++ S +
Sbjct: 1671 IFAQSKESEKKLKSLEAEILQLQE-ELASSERARRHAEQERDELADEITNSASGKSALLD 1729
Query: 182 RAELSEGKCAELEEELKTVTNNLKSL---------------------EAQAEKYSQKEDR 220
E + A+LEEEL+ +N++ L + A+K +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQ 1789
Query: 221 YEEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
E + K L KL+E E +++F + +++ LE I LEE++ +E + ++++ +T
Sbjct: 1790 LERQNKELKAKLQELEGAVKSKF-KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848
Query: 279 LELNNM 284
+L +
Sbjct: 1849 KKLKEI 1854
Score = 65.5 bits (158), Expect = 5e-11
Identities = 73/284 (25%), Positives = 127/284 (44%), Gaps = 25/284 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE-------DE 56
++K Q L+ D + + + K +E + K+L+ ++ L K+ + ++
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKL 113
K L + LE AEKK D ASL ++Q +E E R + L++ +++L
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL 1341
Query: 114 EEAEKAADESERGMKVIESRAQKDEEKMEIQ-EIQLKEAKHIAED---ADRKYEEVARKL 169
EE + + E + E A+K+ EK + + QL + K +D EE +KL
Sbjct: 1342 EEEKNSLQEQQEE----EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL 1397
Query: 170 V-IIESDLERAEERA---ELSEGKCAELEEELKTVTNNL---KSLEAQAEKYSQKEDRYE 222
+ E+ +R EE+A + E L++EL +T +L + + + EK +K D+
Sbjct: 1398 LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E K +S + E RAE R S+ E+ AKEE
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Score = 63.9 bits (154), Expect = 2e-10
Identities = 51/232 (21%), Positives = 114/232 (49%), Gaps = 21/232 (9%)
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E L+ E+L ++K T E ++ + R+ Q + EE + E+L + E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 116 AEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE---V 165
AE+ E E + +ESR +++EE+ +I + + K+ + +D + + +E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 166 ARKL----VIIESDLERAEERAELSEGKCAE-------LEEELKTVTNNLKSLEAQAEKY 214
+KL V E+ +++ EE L E + ++ +E+ + ++ L E +A+
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
++ ++ E I L ++LK+ E + E++ KL+ DL++++A + +
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Score = 62.8 bits (151), Expect = 3e-10
Identities = 64/301 (21%), Positives = 137/301 (45%), Gaps = 25/301 (8%)
Query: 1 MDAIKKKMQMLKLDKENAL--DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
++ + + ++ K+++E L D+ + +KK EDR + +L ++K K +
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 59 KYSEALKDAQEKLELAEK--------------KATDAEADVASLNRRIQLVEEELDRAQE 104
K + D +E+L+ EK + TD + +A L +I ++ +L + +E
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
L AL + ++ + + + ++ ++++ + +E E ++ +A+ D + E
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEA 1150
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
+ +L E L+ + EL + E+ E K + K+ EAQ + Q R+
Sbjct: 1151 LKTEL---EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ---RHATA 1204
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDL--EEKV-AHAKEENLSMHQMLDQTLLEL 281
++ LS++L++A+ E++ LE +L E KV K E+ + LD + EL
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 282 N 282
+
Sbjct: 1265 H 1265
Score = 62.0 bits (149), Expect = 6e-10
Identities = 79/327 (24%), Positives = 143/327 (43%), Gaps = 54/327 (16%)
Query: 2 DAIKKKMQ--MLKLDK-ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL- 57
+A+ ++++ L DK E +R +Q D D +Q+ L QKK D+L
Sbjct: 1402 EALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF----DQLL 1457
Query: 58 -DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL 113
++ S + + A+E+ + AE +A + E SL R ++ +EE +R ++L ++ L
Sbjct: 1458 AEEKSISARYAEER-DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL 1516
Query: 114 ----EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE-EVARK 168
++ K E E+ + +E + E+M Q +L++ EDA + E +
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQV----EEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572
Query: 169 LVIIESDL----ERAEERAELSEGKCAELEEEL--------------KTVTNNLKSLEAQ 210
E DL E+ EE+ L + ELE EL K + +LK LEAQ
Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
Query: 211 AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA--------------ERSVTKLEKSIDDL 256
E ++ D ++++ L ++K+ + E A E+ + LE I L
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692
Query: 257 EEKVAHAKEENLSMHQMLDQTLLELNN 283
+E++A ++ Q D+ E+ N
Sbjct: 1693 QEELASSERARRHAEQERDELADEITN 1719
Score = 61.6 bits (148), Expect = 7e-10
Identities = 68/274 (24%), Positives = 125/274 (45%), Gaps = 34/274 (12%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+D + Q L+L+K AEA K E+ LED+ K+ K ED + +
Sbjct: 959 LDEEEGARQKLQLEKVT-------AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
S L + +EK + K E ++ L R++ +EE R Q+LE+A++
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLEERLK--KEEKTR---------QELEKAKRKL 1060
Query: 121 DESERGM--KVIESRAQKDEEKMEI--QEIQLKEAKHIAED-------ADRKYEEVARKL 169
D + ++ E +AQ DE K+++ +E +L+ A +D A + E+ ++
Sbjct: 1061 DGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQI 1120
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLK----SLEAQAEKYSQKEDRYEEEI 225
++ D E + +E + +L EEL+ + L+ + AQ E +++E E
Sbjct: 1121 AELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Query: 226 KVLSDKLKEAETR-AEFAERSVTKLEKSIDDLEE 258
K L ++ K E + + +R T LE+ + LE+
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
Score = 60.8 bits (146), Expect = 1e-09
Identities = 58/263 (22%), Positives = 122/263 (46%), Gaps = 17/263 (6%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDA-QEKLELAEKKATDAE--ADVASLN 89
E+ + ++EL+ +++K E EL++ + +EK LAE+ + E A+ +
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK--VIESRAQKDEEKMEIQEIQ 147
R+ ++EL+ L + +++ EE + ++ M+ + + Q DEE+ Q++Q
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 148 LKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAE----LEEELKTVTNN 203
L++ A+ K +++ +++++E + + +L E + AE L EE + N
Sbjct: 971 LEKVT-----AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 204 LKSLEAQAEKYSQKEDRYEEEIKV---LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
K Q S E+R ++E K L ++ + + + +L+ ID+L+ ++
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL 1085
Query: 261 AHAKEENLSMHQMLDQTLLELNN 283
A +EE D L NN
Sbjct: 1086 AKKEEELQGALARGDDETLHKNN 1108
Score = 60.8 bits (146), Expect = 1e-09
Identities = 64/316 (20%), Positives = 142/316 (44%), Gaps = 39/316 (12%)
Query: 4 IKKKMQMLKLDKENALD----------RAEQAEAD-KKAAEDRSKQLEDELVSLQKKLKG 52
+ ++++ LK + E+ LD + EQ A+ KKA E+ +K E ++ ++++
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+EL + E K + LE ++ ++A + +Q V+ E + +++L +Q+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 113 L------------EEAEKAA------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHI 154
L E AEKA+ D ++ E + K + E QL++ + +
Sbjct: 1264 LHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 155 AEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA--- 211
++ R+ ++ ++ +E + +E+ E E LE+++ + + L + +
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 212 ----EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE-- 265
E + + + ++ + LS +L+E + E++ +L++ +DDL + H ++
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 266 ENLSMHQ-MLDQTLLE 280
NL Q DQ L E
Sbjct: 1444 SNLEKKQKKFDQLLAE 1459
Score = 54.7 bits (130), Expect = 9e-08
Identities = 62/271 (22%), Positives = 129/271 (47%), Gaps = 19/271 (7%)
Query: 2 DAIKKKMQMLKLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVS----LQKKLKGTEDE 56
+ +K K + K++ E ++R Q ++K Q E EL + ++ +L + E
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919
Query: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ-ERLATALQKLEE 115
L+ E L D + ++E E++ + + + IQ +EE+LD + R L+K+
Sbjct: 920 LE---EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV-T 975
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR---KLVII 172
AE + E + ++E + K ++ ++ E ++ E + + K + +A+ K ++
Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 1035
Query: 173 ESDLE---RAEE--RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
SDLE + EE R EL + K +L+ E + + + L+AQ ++ + + EEE++
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAK-RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+ + A + V +L+ I +L+E
Sbjct: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Score = 53.1 bits (126), Expect = 3e-07
Identities = 37/260 (14%), Positives = 116/260 (44%), Gaps = 3/260 (1%)
Query: 10 MLKLDKENALDRAEQAEADKKAAEDRSKQLEDEL---VSLQKKLKGTEDELDKYSEALKD 66
+L+ ++ + A+ A + + +D + L++E ++L +++ E+E + E ++
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+E + EK+ ++ +A +++ ++ +E L+ E + +E
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
+E + +++++ + L + +A + ++K ++ + L +S R E + +
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA 1474
Query: 187 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
E + E E + ++ L+ E++ ++ + +++ L + E+S
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
Query: 247 TKLEKSIDDLEEKVAHAKEE 266
LE+ ++++ ++ ++E
Sbjct: 1535 RALEQQVEEMRTQLEELEDE 1554
Score = 46.6 bits (109), Expect = 2e-05
Identities = 45/196 (22%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
S +K +L++ ++ LK ++LE A K + +A +++L +I +EE+L++ +
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAVK--SKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A A + + EK E ++ A + +E+ME ++K+ K E+A+ EE
Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAE---EE 1892
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK---SLEAQAEKYSQKEDRY 221
R ++ E +EG L E+ T+ N L+ + + + +++
Sbjct: 1893 ATRANASRRKLQRELDDATEANEG----LSREVSTLKNRLRRGGPISFSSSRSGRRQLHL 1948
Query: 222 EEEIKVLSDKLKEAET 237
E LSD E++T
Sbjct: 1949 EGASLELSDDDTESKT 1964
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%)
Query: 146 IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLK 205
+Q+ + + D + +V K +E +LE E + + + L E+L+ T
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 206 SLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKE 265
E + + K+ EE + L +++E E R + + K++ I DLEE++ +E
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL--DEE 962
Query: 266 ENLSMHQMLDQTLLE 280
E L++ E
Sbjct: 963 EGARQKLQLEKVTAE 977
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 17/155 (10%)
Query: 5 KKKMQMLKLDKENALDRAEQAEAD--KKAAEDRSKQLEDELVSLQ----KKLKGT----- 53
K +Q+ L+ E A +R+ ++D ++ E ++K+L+ +L L+ K K T
Sbjct: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALE 1820
Query: 54 ------EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLA 107
E++L++ ++ A + + EKK + V R +E++++A R+
Sbjct: 1821 AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
++LEEAE+ A + + ++ E E
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 77.4 bits (189), Expect = 1e-14
Identities = 65/270 (24%), Positives = 129/270 (47%), Gaps = 22/270 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1702
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+L+EAE ++ + KL++ +D+ E
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATE 1912
Score = 72.0 bits (175), Expect = 6e-13
Identities = 56/243 (23%), Positives = 116/243 (47%), Gaps = 9/243 (3%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 969
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1029
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+++E I L +LK+ E + E+ KLE D E++A + + + L +
Sbjct: 1030 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 279 LEL 281
EL
Sbjct: 1090 EEL 1092
Score = 71.6 bits (174), Expect = 7e-13
Identities = 70/298 (23%), Positives = 139/298 (46%), Gaps = 25/298 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 SEALK-----DAQEKLELAEKKATDAEADVASLNRRIQLVEEEL--DRAQERLATALQK- 112
+ALK D Q + E E+K L R++ E EL +R Q LA A +K
Sbjct: 1569 MQALKGQFERDLQARDEQNEEKR-------RQLQRQLHEYETELEDERKQRALAAAAKKK 1621
Query: 113 ----LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 168
L++ E AD + +G + + +K + +M+ + +L++A+ ++ +E +K
Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+E+DL + +E +E + + E + + L S + ++ R E I L
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1741
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAK---EENLSMHQMLDQTLLELNN 283
++L+E + E V K + + L ++A + ++N S Q L++ EL +
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Score = 71.2 bits (173), Expect = 9e-13
Identities = 64/280 (22%), Positives = 129/280 (46%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Score = 68.6 bits (166), Expect = 6e-12
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 29/294 (9%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
KMQ+ K ++E AL R + A K A + ++LE + LQ+ L +K +
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+D E+LE + + D A+ ++EL +E+ T L+K + E + E++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTAT--------QQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
++ QK + +E QL++ K + D+ + + ++ + +L + +
Sbjct: 1194 -----VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 185 LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
E K +LE +++ + + E + + K + + E++ ++ L EAE +A +
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
Query: 245 SVTKLEKSIDDLEE--------------KVAHAKEENLSMHQMLDQTLLELNNM 284
V L + D +E K+ +EE S+ LD+ + N+
Sbjct: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 27/283 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1161 STATQQE-LRAKREQEVTVLKKALDEE--TRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 116 AEKAADESER-----------GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ ++V+ Q+ E K + E Q++E + D +R E
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE-------AQAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Score = 66.6 bits (161), Expect = 2e-11
Identities = 49/242 (20%), Positives = 121/242 (50%), Gaps = 21/242 (8%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1758 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ L+ +E + + AE+
Sbjct: 1813 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQ 1867
Query: 182 RAELSE----------GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDK 231
E +E + E EEE + + N + L+ + ++ ++ + E+ L K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Query: 232 LK 233
L+
Sbjct: 1928 LR 1929
Score = 63.9 bits (154), Expect = 2e-10
Identities = 59/303 (19%), Positives = 141/303 (46%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1264
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1265 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 281 LNN 283
L+N
Sbjct: 1436 LDN 1438
Score = 63.9 bits (154), Expect = 2e-10
Identities = 69/319 (21%), Positives = 131/319 (41%), Gaps = 49/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++++ + + E+ + A A KK E K LE + S K + +L K
Sbjct: 1594 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1653
Query: 64 LKDAQEKLELA--------------EKKATDAEADVASLNRRIQLVEE-------ELDRA 102
+KD Q +LE A EKKA EAD+ L + E E +
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 103 QERLATALQ--------------KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
E LA++L ++ + E+ +E + M+ + R +K ++ E +L
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1773
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS--------EGKCAELEEELKTV 200
+ A+ + +++ R+ + S L E + E K A+LEE+ V
Sbjct: 1774 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ---V 1830
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS---VTKLEKSIDDLE 257
+ +A + QK+ + +E + + D+ K AE E AE+ V +L++ +++ E
Sbjct: 1831 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+ + + LD+
Sbjct: 1891 EESQRINANRRKLQRELDE 1909
Score = 63.2 bits (152), Expect = 3e-10
Identities = 70/286 (24%), Positives = 136/286 (47%), Gaps = 35/286 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 908 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + +D + K + RKL+ E
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVM-----------DDQNNKLSK-ERKLL---------E 1005
Query: 181 ERAELSEGKCAELEEELKTVT---NNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
ER AE EE+ K +T N +S+ ++ E +KE++ +E++ L KL E
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL---EG 1062
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
A + L+ I +L+ ++A +EE + LD + + NN
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN 1108
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/288 (22%), Positives = 131/288 (45%), Gaps = 33/288 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1108
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1109 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 236 --ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1165 QQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1208
Score = 56.6 bits (135), Expect = 2e-08
Identities = 56/274 (20%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1358
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1419 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1475 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 244 RSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQT 277
++V +LEKS LE ++ K + + L T
Sbjct: 1525 KNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Score = 55.5 bits (132), Expect = 5e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 28/284 (9%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1475
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1536 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1588
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 248 KLEKSIDDLEEKVAHAK----------EENLSMHQMLDQTLLEL 281
KL+ + D + ++ A+ +EN + L+ L++L
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Score = 55.1 bits (131), Expect = 7e-08
Identities = 45/187 (24%), Positives = 85/187 (45%), Gaps = 3/187 (1%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 904
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 216
+A+ +A K +E L E R E E + +L+ E K + + LE Q E+
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ + E K+K+ E + KL K LEE+++ NL+ + +
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL-TTNLAEEEEKAK 1023
Query: 277 TLLELNN 283
L +L N
Sbjct: 1024 NLTKLKN 1030
Score = 46.6 bits (109), Expect = 2e-05
Identities = 48/262 (18%), Positives = 109/262 (41%), Gaps = 25/262 (9%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
D+ + + + ++ + E + + L K ++ S L+D QE L+
Sbjct: 1280 DKVHKLQNEVESVTGMLNEAEGKAIKLAK-------DVASLSSQLQDTQELLQ------- 1325
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
+ +++ +++ +EEE + Q+ +L+E +A ER + + + ++
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQD-------QLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT 199
K++ E+ +++++ L + A ++ E ++ + + ++L
Sbjct: 1379 KLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 200 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
+N + L + EK +K D+ E K +S K + RAE R S+ E+
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 260 VAHAKEENLSMHQMLDQTLLEL 281
AKEE ++ML + +L
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDL 1516
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE---ADVASLNRRIQ 93
+Q+E E Q K + + K E L +++ ++AE+ AE A V L R+++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
EEE R ++L+EA ++ + R + ++S+ ++ E + + +
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS-RRSGGRR 1946
Query: 154 IAEDADRKYEE 164
+ E+AD EE
Sbjct: 1947 VIENADGSEEE 1957
Score = 38.1 bits (87), Expect = 0.009
Identities = 40/198 (20%), Positives = 90/198 (45%), Gaps = 39/198 (19%)
Query: 2 DAIKKKMQMLK-LDKENALDR--AEQAEADKKAAEDRSKQLEDEL--------------- 43
D ++K Q + L E A +R A++ E+ ++ E ++K+L +L
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
Query: 44 VSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+L+ K+ E+++++ + + A + L+ +KK + V + + +E+ ++
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
R+ ++LEEAE +ES+R I + +K + ++ ++A E
Sbjct: 1877 ARVKQLKRQLEEAE---EESQR----INANRRKLQREL--------------DEATESNE 1915
Query: 164 EVARKLVIIESDLERAEE 181
+ R++ ++S L R E
Sbjct: 1916 AMGREVNALKSKLRRGNE 1933
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 77.4 bits (189), Expect = 1e-14
Identities = 65/270 (24%), Positives = 129/270 (47%), Gaps = 22/270 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1709
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARK 168
+ A++ + S AQK+E +++E Q +L+ H E A + K++ + K
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1829
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ +E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L
Sbjct: 1830 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+L+EAE ++ + KL++ +D+ E
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATE 1919
Score = 72.0 bits (175), Expect = 6e-13
Identities = 56/243 (23%), Positives = 116/243 (47%), Gaps = 9/243 (3%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 105 -RLATALQKLEE-----AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E + +
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEAARQKL 976
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 218
+ K+ +E ++ +++ + LEE + +T NL E +A+ ++ +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLK 1036
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTL 278
+++E I L +LK+ E + E+ KLE D E++A + + + L +
Sbjct: 1037 NKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 279 LEL 281
EL
Sbjct: 1097 EEL 1099
Score = 71.6 bits (174), Expect = 7e-13
Identities = 70/298 (23%), Positives = 139/298 (46%), Gaps = 25/298 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 61 SEALK-----DAQEKLELAEKKATDAEADVASLNRRIQLVEEEL--DRAQERLATALQK- 112
+ALK D Q + E E+K L R++ E EL +R Q LA A +K
Sbjct: 1576 MQALKGQFERDLQARDEQNEEKR-------RQLQRQLHEYETELEDERKQRALAAAAKKK 1628
Query: 113 ----LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 168
L++ E AD + +G + + +K + +M+ + +L++A+ ++ +E +K
Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+E+DL + +E +E + + E + + L S + ++ R E I L
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL 1748
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAK---EENLSMHQMLDQTLLELNN 283
++L+E + E V K + + L ++A + ++N S Q L++ EL +
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Score = 71.2 bits (173), Expect = 9e-13
Identities = 64/280 (22%), Positives = 129/280 (46%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Score = 68.6 bits (166), Expect = 6e-12
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 29/294 (9%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
KMQ+ K ++E AL R + A K A + ++LE + LQ+ L +K +
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+D E+LE + + D A+ ++EL +E+ T L+K + E + E++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTAT--------QQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
++ QK + +E QL++ K + D+ + + ++ + +L + +
Sbjct: 1201 -----VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 185 LSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
E K +LE +++ + + E + + K + + E++ ++ L EAE +A +
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Query: 245 SVTKLEKSIDDLEE--------------KVAHAKEENLSMHQMLDQTLLELNNM 284
V L + D +E K+ +EE S+ LD+ + N+
Sbjct: 1316 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1369
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 27/283 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1168 STATQQE-LRAKREQEVTVLKKALDEE--TRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 116 AEKAADESER-----------GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ ++V+ Q+ E K + E Q++E + D +R E
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE-------AQAEKYSQK 217
+ K+ +++++E +EGK +L +++ ++++ L+ + Q S K
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ EEE L D+L E + ER ++ L + D ++K+
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Score = 66.6 bits (161), Expect = 2e-11
Identities = 49/242 (20%), Positives = 121/242 (50%), Gaps = 21/242 (8%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1705 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1765 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ L+ +E + + AE+
Sbjct: 1820 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQ 1874
Query: 182 RAELSE----------GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDK 231
E +E + E EEE + + N + L+ + ++ ++ + E+ L K
Sbjct: 1875 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Query: 232 LK 233
L+
Sbjct: 1935 LR 1936
Score = 63.9 bits (154), Expect = 2e-10
Identities = 59/303 (19%), Positives = 141/303 (46%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1271
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1272 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 281 LNN 283
L+N
Sbjct: 1443 LDN 1445
Score = 63.9 bits (154), Expect = 2e-10
Identities = 69/319 (21%), Positives = 131/319 (41%), Gaps = 49/319 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++++ + + E+ + A A KK E K LE + S K + +L K
Sbjct: 1601 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1660
Query: 64 LKDAQEKLELA--------------EKKATDAEADVASLNRRIQLVEE-------ELDRA 102
+KD Q +LE A EKKA EAD+ L + E E +
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 103 QERLATALQ--------------KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
E LA++L ++ + E+ +E + M+ + R +K ++ E +L
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1780
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS--------EGKCAELEEELKTV 200
+ A+ + +++ R+ + S L E + E K A+LEE+ V
Sbjct: 1781 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ---V 1837
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS---VTKLEKSIDDLE 257
+ +A + QK+ + +E + + D+ K AE E AE+ V +L++ +++ E
Sbjct: 1838 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Query: 258 EKVAHAKEENLSMHQMLDQ 276
E+ + + LD+
Sbjct: 1898 EESQRINANRRKLQRELDE 1916
Score = 63.2 bits (152), Expect = 3e-10
Identities = 70/286 (24%), Positives = 136/286 (47%), Gaps = 35/286 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 915 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + +D + K + RKL+ E
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVM-----------DDQNNKLSK-ERKLL---------E 1012
Query: 181 ERAELSEGKCAELEEELKTVT---NNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
ER AE EE+ K +T N +S+ ++ E +KE++ +E++ L KL E
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKL---EG 1069
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
A + L+ I +L+ ++A +EE + LD + + NN
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN 1115
Score = 61.6 bits (148), Expect = 7e-10
Identities = 66/288 (22%), Positives = 131/288 (45%), Gaps = 33/288 (11%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEDELVSLQK----------KLKGTEDELDKYS 61
E DR +Q +A++K D +QLE+E + QK K+K EDE+
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++ +L E++ +D ++A + + + + ++ + ++ +L++ EK+
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E+ + +E A E++ + Q+ E K +K EE+ L ++ ++ +
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQAALARLDDEIAQKNN 1115
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA------ 235
+ K ELE + + +L S A K +++ EE++ L +L++
Sbjct: 1116 ALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 236 --ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E RA+ E+ VT L+K++D EE +H + M Q Q + EL
Sbjct: 1172 QQELRAK-REQEVTVLKKALD--EETRSHEAQVQ-EMRQKHAQAVEEL 1215
Score = 56.6 bits (135), Expect = 2e-08
Identities = 56/274 (20%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1365
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + ++ E RK++++ + I S +RA
Sbjct: 1426 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E +E + E+E K + SL E+ + ++ E K+L ++++ + +
Sbjct: 1482 E-AEAR----EKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1531
Query: 244 RSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQT 277
++V +LEKS LE ++ K + + L T
Sbjct: 1532 KNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Score = 55.5 bits (132), Expect = 5e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 28/284 (9%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1482
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1483 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1542
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1543 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1595
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
K +L+ +L L+ Q + + + E ++K L + A E A + +
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 248 KLEKSIDDLEEKVAHAK----------EENLSMHQMLDQTLLEL 281
KL+ + D + ++ A+ +EN + L+ L++L
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699
Score = 55.1 bits (131), Expect = 7e-08
Identities = 45/187 (24%), Positives = 85/187 (45%), Gaps = 3/187 (1%)
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQEIQLKEAKHIAE 156
++ R +E + +L++ ++ ++E +K +E + +Q EEK +QE QL+ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE-QLQAETELYA 911
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 216
+A+ +A K +E L E R E E + +L+ E K + + LE Q E+
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ + E K+K+ E + KL K LEE+++ NL+ + +
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL-TTNLAEEEEKAK 1030
Query: 277 TLLELNN 283
L +L N
Sbjct: 1031 NLTKLKN 1037
Score = 46.6 bits (109), Expect = 2e-05
Identities = 48/262 (18%), Positives = 109/262 (41%), Gaps = 25/262 (9%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
D+ + + + ++ + E + + L K ++ S L+D QE L+
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAK-------DVASLSSQLQDTQELLQ------- 1332
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
+ +++ +++ +EEE + Q+ +L+E +A ER + + + ++
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQD-------QLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT 199
K++ E+ +++++ L + A ++ E ++ + + ++L
Sbjct: 1386 KLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 200 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 259
+N + L + EK +K D+ E K +S K + RAE R S+ E+
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 260 VAHAKEENLSMHQMLDQTLLEL 281
AKEE ++ML + +L
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDL 1523
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE---ADVASLNRRIQ 93
+Q+E E Q K + + K E L +++ ++AE+ AE A V L R+++
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
EEE R ++L+EA ++ + R + ++S+ ++ E + + +
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS-RRSGGRR 1953
Query: 154 IAEDADRKYEE 164
+ E+AD EE
Sbjct: 1954 VIENADGSEEE 1964
Score = 38.1 bits (87), Expect = 0.009
Identities = 40/198 (20%), Positives = 90/198 (45%), Gaps = 39/198 (19%)
Query: 2 DAIKKKMQMLK-LDKENALDR--AEQAEADKKAAEDRSKQLEDEL--------------- 43
D ++K Q + L E A +R A++ E+ ++ E ++K+L +L
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1823
Query: 44 VSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+L+ K+ E+++++ + + A + L+ +KK + V + + +E+ ++
Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
R+ ++LEEAE +ES+R I + +K + ++ ++A E
Sbjct: 1884 ARVKQLKRQLEEAE---EESQR----INANRRKLQREL--------------DEATESNE 1922
Query: 164 EVARKLVIIESDLERAEE 181
+ R++ ++S L R E
Sbjct: 1923 AMGREVNALKSKLRRGNE 1940
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.120 0.290
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,460,662
Number of Sequences: 37866
Number of extensions: 396191
Number of successful extensions: 16834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 807
Number of HSP's successfully gapped in prelim test: 1044
Number of HSP's that attempted gapping in prelim test: 3346
Number of HSP's gapped (non-prelim): 6898
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.