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Search of human proteins with 61835172
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61835172 fragile X mental retardation-related protein 1
isoform c [Homo sapiens]
(536 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61835172 fragile X mental retardation-related protein 1 isofo... 1059 0.0
gi|61835148 fragile X mental retardation-related protein 1 isofo... 1059 0.0
gi|61835164 fragile X mental retardation-related protein 1 isofo... 893 0.0
gi|4758410 fragile X mental retardation syndrome related protein... 586 e-167
gi|4503765 fragile X mental retardation 1 [Homo sapiens] 366 e-101
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 43 8e-04
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 43 8e-04
gi|17402900 far upstream element-binding protein [Homo sapiens] 42 0.002
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.005
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 40 0.005
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.007
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.007
gi|239048862 checkpoint with forkhead and ring finger domains is... 39 0.009
gi|239048792 checkpoint with forkhead and ring finger domains is... 39 0.009
gi|52426743 cisplatin resistance-associated overexpressed protei... 39 0.009
gi|19923485 cisplatin resistance-associated overexpressed protei... 39 0.009
gi|60097902 filaggrin [Homo sapiens] 39 0.016
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 39 0.016
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 38 0.020
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 38 0.027
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 38 0.027
gi|194097341 period 1 [Homo sapiens] 37 0.035
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 37 0.045
gi|217330641 IWS1 homolog [Homo sapiens] 37 0.045
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 37 0.045
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 37 0.059
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 37 0.059
>gi|61835172 fragile X mental retardation-related protein 1 isoform
c [Homo sapiens]
Length = 536
Score = 1059 bits (2739), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN
Sbjct: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
Query: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA
Sbjct: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
Query: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY
Sbjct: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
Query: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK
Sbjct: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
Query: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300
LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG
Sbjct: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300
Query: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360
RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR
Sbjct: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360
Query: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420
GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR
Sbjct: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420
Query: 421 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 480
SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM
Sbjct: 421 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 480
Query: 481 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 536
AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS
Sbjct: 481 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 536
>gi|61835148 fragile X mental retardation-related protein 1 isoform
a [Homo sapiens]
Length = 621
Score = 1059 bits (2739), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN
Sbjct: 86 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 145
Query: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA
Sbjct: 146 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 205
Query: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY
Sbjct: 206 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 265
Query: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK
Sbjct: 266 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 325
Query: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300
LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG
Sbjct: 326 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 385
Query: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360
RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR
Sbjct: 386 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 445
Query: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420
GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR
Sbjct: 446 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 505
Query: 421 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 480
SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM
Sbjct: 506 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 565
Query: 481 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 536
AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS
Sbjct: 566 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 621
>gi|61835164 fragile X mental retardation-related protein 1 isoform
b [Homo sapiens]
Length = 539
Score = 893 bits (2307), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN
Sbjct: 86 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 145
Query: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA
Sbjct: 146 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 205
Query: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY
Sbjct: 206 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 265
Query: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK
Sbjct: 266 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 325
Query: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300
LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG
Sbjct: 326 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 385
Query: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360
RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR
Sbjct: 386 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 445
Query: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420
GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR
Sbjct: 446 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 505
Query: 421 SRRRRTDEDAVLMDGMTESDTASVNENGL 449
SRRRRTDEDAVLMDGMTESDTASVNENGL
Sbjct: 506 SRRRRTDEDAVLMDGMTESDTASVNENGL 534
>gi|4758410 fragile X mental retardation syndrome related protein 2
[Homo sapiens]
Length = 673
Score = 586 bits (1510), Expect = e-167
Identities = 342/614 (55%), Positives = 403/614 (65%), Gaps = 114/614 (18%)
Query: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
MMKG+FYVIEYAACDATYNEIVT ERLRPVN N K +FFK T+ VPEDLREAC+NEN
Sbjct: 96 MMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATKGSFFKVTMAVPEDLREACSNEN 155
Query: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
HK+FKKA+GA IF + ++L ILS +EA VKR ++L DMH RS+RTKL+LMSRNEEA
Sbjct: 156 VHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEA 215
Query: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
TKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQARKVPGVTAIEL E+T TFRIY
Sbjct: 216 TKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTFRIY 275
Query: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
GE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKVIQEIVDKSGVVRVR+EGDN+ K
Sbjct: 276 GETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKK 335
Query: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIG------ 294
PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQLR+ERLQIDEQLRQIG
Sbjct: 336 NPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPP 395
Query: 295 ------------------------------SRSYSGRGRGRR--GPNYTSGYGTNSELSN 322
SY GRGRGRR GP YG +S++S
Sbjct: 396 GSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGP----AYGPSSDVST 451
Query: 323 PSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGGRGRSVSGGRGRGGP-------R 374
SETESE+++E + AG DRD +SRRRP +GGRGRG P R
Sbjct: 452 ASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-------TGGRGRGPPPAPRPTSR 501
Query: 375 GGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMD 434
SSISSVLKDPDSNPYSLLD +E + D++ E ++ RRRRSRRRRTDED +MD
Sbjct: 502 YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMD 561
Query: 435 GMTESDTASVNENGL--------------------------------VTVADYISRAESQ 462
G ESD ++ ENGL VTVADYISRAESQ
Sbjct: 562 GGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQ 621
Query: 463 SRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLK 522
SRQ +E PSE +++G GD +SKL + P E N
Sbjct: 622 SRQ----------------SAPLERTKPSEDSLSG---QKGDSVSKLPKGPSE---NGEL 659
Query: 523 EENTQEAAVLNGVS 536
+ +++NGVS
Sbjct: 660 SAPLELGSMVNGVS 673
>gi|4503765 fragile X mental retardation 1 [Homo sapiens]
Length = 632
Score = 366 bits (939), Expect = e-101
Identities = 183/249 (73%), Positives = 209/249 (83%)
Query: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60
M+KGEFYVIEYAACDATYNEIVT ERLR VN NK K+TF K +DVPEDLR+ CA E
Sbjct: 86 MIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEA 145
Query: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120
AHKDFKKAVGA + Y PE QL+ILS +E T KR ++L DMH RS+RTKL L+ RNEEA
Sbjct: 146 AHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEA 205
Query: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180
+K LE ++QLA+ FHE+F+VREDLMGLAIGTHG+NIQQARKVPGVTAI+LDEDT TF IY
Sbjct: 206 SKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIY 265
Query: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240
GE DAVKKAR FLEF ED IQVPRNLVGKVIGKNGK+IQEIVDKSGVVRVRIE +NE
Sbjct: 266 GEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKN 325
Query: 241 LPREDGMVP 249
+P+E+ ++P
Sbjct: 326 VPQEEEIMP 334
Score = 162 bits (409), Expect = 9e-40
Identities = 132/350 (37%), Positives = 166/350 (47%), Gaps = 74/350 (21%)
Query: 134 FHEEFV-VREDLMGLAIGTHGSNIQQARKVPGVTAIELDED------------------T 174
F E+ + V +L+G IG +G IQ+ GV + ++ + +
Sbjct: 281 FAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPS 340
Query: 175 GTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIE 234
R+ G +A KK E F Q N +Q ++ S VV
Sbjct: 341 NNSRV-GPNAPEEKKHLDIKENSTHFSQ-----------PNSTKVQRVLVASSVVA---- 384
Query: 235 GDNEN-KLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQI 293
G+++ +L GMVPFVFVGTK+SI N VLL+YH+ YLKEV+QLR+ERLQIDEQLRQI
Sbjct: 385 GESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQI 444
Query: 294 ---------------------------GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSET 326
GSR Y RG GRRGP YTS GTNSE SN SET
Sbjct: 445 GASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTS--GTNSEASNASET 502
Query: 327 ESERKDELSDWSLA-GEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLK 385
ES+ +DELSDWSLA E++R+S +R RR GG GR GGRGRGG G S
Sbjct: 503 ESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG-QGGRGRGGGFKGNDDHSRTDN 561
Query: 386 DPDSNPYSLLDNTESDQ---TADTDASESHHS---TNRRRRSRRRRTDED 429
P NP T D + S H+ N R RT +D
Sbjct: 562 RP-RNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKD 610
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 137 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 194
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 195 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 241
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 137 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 194
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 195 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 241
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 137 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 194
E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ +
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
Query: 195 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 241
V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L
Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 42.7 bits (99), Expect = 8e-04
Identities = 39/184 (21%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 317 NSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGR-----------SVS 365
+ + N + ++ K + +RDS+H R+ +R R + S
Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504
Query: 366 GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTA-----DTDASESHHSTNRRRR 420
+G+ R +S S + SN + + E D+ A + D ++ HS N R R
Sbjct: 505 DSKGKDQER-SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563
Query: 421 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNL-PRETLAKNKKE 479
R R D + + D + E +Y R S+SR+R P + +K+++
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623
Query: 480 MAKD 483
+D
Sbjct: 624 RRRD 627
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 42.7 bits (99), Expect = 8e-04
Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 33/135 (24%)
Query: 272 YLKEVEQLRMERLQIDEQLRQIGSRS----YSGRG-----RGRRGPNYTSGYGTNSELSN 322
+ KE+ Q R + + R GSR Y GRG RGR + G G S +
Sbjct: 220 FTKELNQYRRAK---EGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGD 276
Query: 323 PSETESERKDELSDWSLA----GEDDRDS--------RHQRDSRRR---------PGGRG 361
E E + +E D+ + G+DD D R +DSR R GRG
Sbjct: 277 HPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGRG 336
Query: 362 RSVSGGRGRGGPRGG 376
+ + GRGRGG RGG
Sbjct: 337 KGMGRGRGRGGSRGG 351
Score = 32.7 bits (73), Expect = 0.86
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 12/113 (10%)
Query: 325 ETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG--------- 375
E E K++ D++ R ++ R GRGR G RGG RG
Sbjct: 208 EEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRG 267
Query: 376 -GKSSISSVLKDPDSNPY-SLLDNTESDQ-TADTDASESHHSTNRRRRSRRRR 425
G+ S+ + + + Y +D ES++ D D E N+ RRS+ R
Sbjct: 268 RGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSR 320
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 48/205 (23%)
Query: 136 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDE---DTGT---FRIYGES------ 183
+E ++ GL IG G I+Q ++ GV + + + +TG RI G+
Sbjct: 188 QEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQA 247
Query: 184 ----ADAVKKARGFLEFVEDF-----------IQVPRNLVGKVIGKNGKVIQEIVDKSGV 228
+ ++ GF E ++ + +PR VG VIG+NG++I++I + +G
Sbjct: 248 KEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAG- 306
Query: 229 VRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDE 288
VR++ + D DG P Q E L+ V
Sbjct: 307 VRIQFKPD--------DGTTPERIAQITGPPDRCQHAAEIITDLLRSV------------ 346
Query: 289 QLRQIGSRSYSGRGRGRRGPNYTSG 313
Q G GRGRGR N+ G
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMG 371
Score = 37.7 bits (86), Expect = 0.027
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 24/135 (17%)
Query: 128 KQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFR----IYGES 183
+Q + EE+ V + ++G IG G I + ++ G I++ D+G + +
Sbjct: 95 QQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCK-IQIAPDSGGLPERSCMLTGT 153
Query: 184 ADAVKKARGFLEFVEDF-------------------IQVPRNLVGKVIGKNGKVIQEIVD 224
++V+ A+ L+ + + I +P + G VIGK G+ I+++ +
Sbjct: 154 PESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQE 213
Query: 225 KSGVVRVRIEGDNEN 239
++GV V I+ +N
Sbjct: 214 RAGVKMVMIQDGPQN 228
Score = 32.0 bits (71), Expect = 1.5
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 192 GFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFV 251
G EF +FI VP G +IGK G+ I+ I +SG RIE + M F
Sbjct: 375 GLQEF--NFI-VPTGKTGLIIGKGGETIKSISQQSG---ARIELQRNPPPNADPNMKLFT 428
Query: 252 FVGTKESIGNVQVLLEYHI 270
GT + I + L+E I
Sbjct: 429 IRGTPQQIDYARQLIEEKI 447
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.0 bits (92), Expect = 0.005
Identities = 48/248 (19%), Positives = 92/248 (37%), Gaps = 5/248 (2%)
Query: 287 DEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD 346
D++ Q + S G N S ++S + S E KD + G +D D
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSR-GDASYNSDESKDNGNGSDSKGAEDDD 514
Query: 347 SRHQRDSRRRPG-GRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTAD 405
S D+ G G + + + GKS S SN D+++SD +
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 406 TDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTA-SVNENGLVTVADYISRAESQSR 464
+S+S S + S + + + D SD++ S + + S++ES S
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634
Query: 465 QRNLPRETLAKNKKEMA--KDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLK 522
+ ++ N + + D + S + + +S S D S + + ++
Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Query: 523 EENTQEAA 530
N+ E++
Sbjct: 695 SSNSSESS 702
Score = 37.7 bits (86), Expect = 0.027
Identities = 38/223 (17%), Positives = 78/223 (34%), Gaps = 2/223 (0%)
Query: 311 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 370
+S +S+ SN S++ S S D DS + DS S S
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 371 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
S +S S+ ++++S ++D+ S+NR S + + +
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 431 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 490
+ SD++ NE+ +D + S + + + + D E
Sbjct: 872 DSSNSSDSSDSSDSNESS--NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 491 SEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLN 533
S+ + + +S S D + + N+ N+ +++ N
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/224 (17%), Positives = 87/224 (38%), Gaps = 14/224 (6%)
Query: 309 NYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGR 368
N +S +S+ SN S+++S SD S DS + DS S S
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSS-------DSSNSSDSSESSNSSDNSNSSDS 938
Query: 369 GRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDE 428
S S+ +S+ D++ S ++D+++S+S S+N S + +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993
Query: 429 DAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM--AKDVIE 486
+ D SD++ +++ + + S + S + + + + + + D +
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Query: 487 EHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 530
S+ + + +S S D + E ++ N+ +++
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Score = 37.0 bits (84), Expect = 0.045
Identities = 40/219 (18%), Positives = 83/219 (37%), Gaps = 4/219 (1%)
Query: 316 TNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRDSRRRPGGRGRSVSGGRGRGGP 373
++S+ S+ S+++S SD S + + D DS DS+ S +
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 374 RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLM 433
SS SS D + S + SD + +D+S S S+N S + +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 434 DG--MTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPS 491
D ++SD++ +++ +D S S S + ++ + + D + S
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 492 EKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 530
+ + +S S D + + N+ ++ ++
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Score = 36.6 bits (83), Expect = 0.059
Identities = 39/195 (20%), Positives = 70/195 (35%), Gaps = 1/195 (0%)
Query: 311 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 370
+S +S+ S+ S++ S S D DS DS S S
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 371 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
S S DS+ S N+ SD + +D+S+S S++ S + + +
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 431 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 490
D SD++ +++ + S + S N + + + + D +E
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDS 1271
Query: 491 SEKAINGPTSASGDD 505
K+ NG + S D
Sbjct: 1272 QSKSGNGNNNGSDSD 1286
Score = 35.8 bits (81), Expect = 0.10
Identities = 39/197 (19%), Positives = 73/197 (37%), Gaps = 20/197 (10%)
Query: 311 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 370
+S +SE S+ S++ + SD S + D DS + DS S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS------- 744
Query: 371 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
SS SS D + S + SD + +D+S+S +S++ S + + +
Sbjct: 745 ------DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798
Query: 431 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 490
D SD++ +++ S + + S N + + N + + G
Sbjct: 799 NSSDSSNSSDSSDSSDSS-------DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 491 SEKAINGPTSASGDDIS 507
+ N S++ D S
Sbjct: 852 DSDSSNRSDSSNSSDSS 868
Score = 35.0 bits (79), Expect = 0.17
Identities = 33/157 (21%), Positives = 65/157 (41%), Gaps = 4/157 (2%)
Query: 295 SRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRD 352
S S + + + +S + S+ S+ + ++S + SD S + D DS D
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 353 SRRRPGGRGRSVSGGRG--RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASE 410
S S S SS SS DS+ S ++++SD + +D+S+
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 411 SHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 447
S +S++ S + + + D SD++ +++
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/221 (19%), Positives = 77/221 (34%), Gaps = 6/221 (2%)
Query: 312 SGYGTNSELSNPSETESERKDEL-SDWSLAGEDDRDSRHQRDS-RRRPGGRGRSVSGGRG 369
S +NS SN S S+ D S S D DS DS S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 370 RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDED 429
SS SS D DS+ S S+ + +D+S+S +S++ S +
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRS----DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Query: 430 AVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHG 489
+ D SD+ S + + +D + ++S + + + +
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Query: 490 PSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 530
S + N S++ D S + + N+ ++ +++
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Score = 33.9 bits (76), Expect = 0.38
Identities = 40/221 (18%), Positives = 79/221 (35%), Gaps = 2/221 (0%)
Query: 312 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 371
S G++S+ SN S++ + S S D DS +S S S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 372 -GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
SS SS D + S ++ SD + +D+S+S S+N S + +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 431 VLMDGMTESDTASVNENGLVTVADYISRAE-SQSRQRNLPRETLAKNKKEMAKDVIEEHG 489
D + + S N + +D ++ S S + ++ + + D
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 490 PSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 530
S + + +S S D + + N+ ++ +++
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Score = 33.9 bits (76), Expect = 0.38
Identities = 42/224 (18%), Positives = 85/224 (37%), Gaps = 5/224 (2%)
Query: 309 NYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGR 368
N + +NS S+ S S+ D S S D DS + DS S S
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSD--SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 369 GRGGPRGGKSSISSVLKDPDSNPYS-LLDNTESDQTADT-DASESHHSTNRRRRSRRRRT 426
S S DS+ S D+++S ++D+ D+S+S S++ S +
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 427 DEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIE 486
E + D SD++ +++ + + S + S N + + + + + D
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-SSDSSN 1140
Query: 487 EHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 530
S+ + + +S S D + + ++ N+ +++
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Score = 29.6 bits (65), Expect = 7.2
Identities = 37/150 (24%), Positives = 54/150 (36%), Gaps = 27/150 (18%)
Query: 311 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 370
+S +S+ SN S++ S S D DS DS
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS----------------- 1210
Query: 371 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
SS SS D + S N SD + +D+S+S +S++ S D
Sbjct: 1211 -----SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS-----DSSD 1260
Query: 431 VLMDGMTESDTASVNENGLVTVADYISRAE 460
D ESD+ S + NG +D S +E
Sbjct: 1261 STSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 40.0 bits (92), Expect = 0.005
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 29/130 (22%)
Query: 136 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDED---TGT---FRIYGESADAVKK 189
+E ++ +GL IG G I+Q ++ GV + + + TG RI G++ +
Sbjct: 165 QEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQA 224
Query: 190 ARGFLEFVE------------DF----------IQVPRNLVGKVIGKNGKVIQEIVDKSG 227
LE + DF + VPR VG VIG+NG++I++I + +G
Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAG 284
Query: 228 VVRVRIEGDN 237
VR++ + D+
Sbjct: 285 -VRIQFKPDD 293
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 7/69 (10%)
Query: 198 EDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKE 257
E+F +VP +VG +IG+ G+ I I +SG +++I ++ R P V GT E
Sbjct: 80 EEF-KVPDKMVGFIIGRGGEQISRIQAESG-CKIQIASESSGIPER-----PCVLTGTPE 132
Query: 258 SIGNVQVLL 266
SI + LL
Sbjct: 133 SIEQAKRLL 141
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 201 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 260
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 261 NVQVLLEYHIAYLKEVE 277
N Q LL+ + +VE
Sbjct: 446 NAQYLLQNSVKQYADVE 462
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 201 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 260
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 261 NVQVLLEYHIAYLKEVE 277
N Q LL+ + +VE
Sbjct: 446 NAQYLLQNSVKQYADVE 462
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 39.3 bits (90), Expect = 0.009
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Query: 214 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 273
K+G+V E SG V +++ + P + G V ++ E NV L E L
Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123
Query: 274 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 333
E + + E + +++ G++ SG G GR G + + PS ++ E
Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173
Query: 334 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 382
S + D + + P GR RS S G G GG P+G S++S
Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 39.3 bits (90), Expect = 0.009
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Query: 214 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 273
K+G+V E SG V +++ + P + G V ++ E NV L E L
Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123
Query: 274 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 333
E + + E + +++ G++ SG G GR G + + PS ++ E
Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173
Query: 334 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 382
S + D + + P GR RS S G G GG P+G S++S
Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 39.3 bits (90), Expect = 0.009
Identities = 67/329 (20%), Positives = 116/329 (35%), Gaps = 36/329 (10%)
Query: 213 GKNGKVIQEIVDKSGVVRVRIEG-DNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIA 271
GKN + IQ + DK V+ +IE +E K+ GM+ V E + + LL +
Sbjct: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV-----EQLKEERELLRSTTS 177
Query: 272 YLKE--VEQLRMERLQIDEQLRQIGSRS--YSGRGRGRRGPNYTSGYGTNSELSNPSETE 327
++ ++ +ME ++ +G G++ Y T EL
Sbjct: 178 TIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKR 237
Query: 328 SERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDP 387
+E D E + + +R+ R + R R R R R + +D
Sbjct: 238 TEEPDR-------DERLKKEKQEREEREKEREREREE---RERKRRREEEEREKERARDR 287
Query: 388 DSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 447
+ S + S +T+D S S R R RRR D S+
Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK----- 342
Query: 448 GLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDIS 507
R+ S+ R+R+ R+ + + ++D ++ EK G S
Sbjct: 343 ---------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 508 KLQRTPGEEKINTLKEENTQEAAVLNGVS 536
+ E+ KE +T+ +NG S
Sbjct: 394 GSREKQSEDTNTESKESDTKNE--VNGTS 420
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 39.3 bits (90), Expect = 0.009
Identities = 67/329 (20%), Positives = 116/329 (35%), Gaps = 36/329 (10%)
Query: 213 GKNGKVIQEIVDKSGVVRVRIEG-DNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIA 271
GKN + IQ + DK V+ +IE +E K+ GM+ V E + + LL +
Sbjct: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV-----EQLKEERELLRSTTS 177
Query: 272 YLKE--VEQLRMERLQIDEQLRQIGSRS--YSGRGRGRRGPNYTSGYGTNSELSNPSETE 327
++ ++ +ME ++ +G G++ Y T EL
Sbjct: 178 TIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKR 237
Query: 328 SERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDP 387
+E D E + + +R+ R + R R R R R + +D
Sbjct: 238 TEEPDR-------DERLKKEKQEREEREKEREREREE---RERKRRREEEEREKERARDR 287
Query: 388 DSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 447
+ S + S +T+D S S R R RRR D S+
Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK----- 342
Query: 448 GLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDIS 507
R+ S+ R+R+ R+ + + ++D ++ EK G S
Sbjct: 343 ---------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393
Query: 508 KLQRTPGEEKINTLKEENTQEAAVLNGVS 536
+ E+ KE +T+ +NG S
Sbjct: 394 GSREKQSEDTNTESKESDTKNE--VNGTS 420
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 38.5 bits (88), Expect = 0.016
Identities = 61/262 (23%), Positives = 98/262 (37%), Gaps = 44/262 (16%)
Query: 290 LRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETES---ERKDELSDWSLAGEDDRD 346
L Q+ + S GR GP+ G+ E + S S E +D + + R
Sbjct: 3711 LYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
Query: 347 SRHQRDSRRRPG--GRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTES---D 401
+ S R G G S + +GR G+S S ++ + S + S
Sbjct: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRH 3830
Query: 402 QTADTDASESHHSTNRRRR---SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISR 458
A T A S HS + + SRR R +V D SD+ + E D R
Sbjct: 3831 HEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD----SDSEAYPE-------DSERR 3879
Query: 459 AESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKI 518
+ES SR + + +E ++D G S + D S +Q +P +
Sbjct: 3880 SESASRNHH-------GSSREQSRDGSRHPGSSHR----------DTASHVQSSPVQSDS 3922
Query: 519 NTLKEEN-----TQEAAVLNGV 535
+T KE +Q++A +G+
Sbjct: 3923 STAKEHGHFSSLSQDSAYHSGI 3944
Score = 35.0 bits (79), Expect = 0.17
Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 24/154 (15%)
Query: 277 EQLRMERLQIDEQLRQIGSRSYSGRGRG-RRGPNYTSGYGTNSEL-SNPSETESERKDEL 334
EQ R Q Q R + G RG R+G +Y ++ S+ S T S+ + ++
Sbjct: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDV 1854
Query: 335 S--------------DWSLAGEDDRDS--RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKS 378
S + +G+ R S RH S R R V G+ GPR ++
Sbjct: 1855 SRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQS-SGPRTSRN 1913
Query: 379 SISSVLKDPDSNPYSLLDNTESDQTADTDASESH 412
SSV +D DS +S E + AS +H
Sbjct: 1914 QGSSVSQDSDSQGHS-----EDSERWSGSASRNH 1942
Score = 33.1 bits (74), Expect = 0.66
Identities = 44/177 (24%), Positives = 62/177 (35%), Gaps = 16/177 (9%)
Query: 288 EQLRQIGSRSYSGRGRGRR-GPNYTSGYGTNSELSNPSETESERKDELSDWSL------A 340
E Q S +S G+G+ GP + G++ + S+ SE + S + A
Sbjct: 590 EASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA 649
Query: 341 GEDDRD-SRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE 399
E RD SRH R G G S R G SS + S +
Sbjct: 650 QEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHG 709
Query: 400 SDQTADTDASESHHSTNR-------RRRSRRRRTDEDAVLMDGMTE-SDTASVNENG 448
S + S H T R R + A +G +E SDT SV+ +G
Sbjct: 710 SRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHG 766
Score = 33.1 bits (74), Expect = 0.66
Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 24/145 (16%)
Query: 304 GRRGPNYT-----SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPG 358
GR+G +Y SG+ + S+ S+ S A R+ D R G
Sbjct: 2472 GRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSG 2531
Query: 359 GRGRSVSG----------GRGRG-GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTD 407
R S G+G+ GPR ++ SS +D DS +S E +
Sbjct: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHS-----EDSERWSGS 2586
Query: 408 ASESHHSTNR---RRRSRRRRTDED 429
AS +HH + + R SR R+ ++
Sbjct: 2587 ASRNHHGSAQEQLRDGSRHPRSHQE 2611
Score = 32.0 bits (71), Expect = 1.5
Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 14/241 (5%)
Query: 295 SRSYSG--RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRD 352
S +SG RG+ + +G++ ++ SE SE D S HQ
Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQES 3371
Query: 353 SRRRPGGR-GRSVS-----GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT 406
+R R GGR GRS S + G++ S+ + + + + S
Sbjct: 3372 ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 3431
Query: 407 DASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQR 466
D H ++ RR R+ E +V G + S + G + S + S SRQ
Sbjct: 3432 DTIRGHPGSS--RRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
Query: 467 NLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENT 526
++ ++ + H S +A + S SG S RT + + ++ ++
Sbjct: 3490 RNDEQSGDGSRHSWS----HHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS 3545
Query: 527 Q 527
Q
Sbjct: 3546 Q 3546
Score = 31.2 bits (69), Expect = 2.5
Identities = 36/155 (23%), Positives = 56/155 (36%), Gaps = 29/155 (18%)
Query: 285 QIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELS---------NPSETESERKDELS 335
Q + R S+ RG GP+ G++ E S + S T S+ + + S
Sbjct: 2121 QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDAS 2180
Query: 336 --------------DWSLAGEDDRDS-RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSI 380
D +G+ R S H ++ S+ G GPR +
Sbjct: 2181 RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRG 2240
Query: 381 SSVLKDPDSNPYSLLDNTESDQTADTDASESHHST 415
SSV +D DS +S E + AS +HH +
Sbjct: 2241 SSVSQDSDSEGHS-----EDSERRSGSASRNHHGS 2270
Score = 30.8 bits (68), Expect = 3.3
Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 15/163 (9%)
Query: 294 GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDS 353
GSR+ +G + + G+ +SE + S + + R S + SRH R
Sbjct: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG------SAQEQSRHGSRHPRSH 988
Query: 354 RRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHH 413
G G S R G P SS + S + S D+S H
Sbjct: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSR-HS 1047
Query: 414 STNRRRRSRRRR-------TDEDAVLMDGMT-ESDTASVNENG 448
RR+ S R + A +G + ESDT SV+ +G
Sbjct: 1048 GIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHG 1090
Score = 30.8 bits (68), Expect = 3.3
Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%)
Query: 277 EQLRMERLQIDEQLRQIGSRSYSGRGR-GRRGPNY----------------TSGYGTNSE 319
EQ R Q Q R + G R GR+G +Y T+ G +
Sbjct: 3416 EQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475
Query: 320 LSNPSETESERKDELSDWSLAGEDDRDS-RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKS 378
S + S + +D +G+ R S H ++ + S SG GPR ++
Sbjct: 3476 SRGQSGSRSASRQTRND-EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRN 3534
Query: 379 SISSVLKDPDSNPYSLLDNTESDQTADTDASESHHST 415
SSV +D DS +S E + AS +H +
Sbjct: 3535 QGSSVSQDSDSQGHS-----EDSERWSGSASRNHRGS 3566
Score = 30.0 bits (66), Expect = 5.5
Identities = 33/154 (21%), Positives = 54/154 (35%), Gaps = 23/154 (14%)
Query: 277 EQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSD 336
EQ R + Q + S + G GRR + G N S ++SE E SD
Sbjct: 1671 EQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESD 1730
Query: 337 WSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLD 396
+ HQ+ + RG+ G R G+S S L
Sbjct: 1731 TQSVSAHGQAGPHQQSHQ----------ESTRGQSGERSGRSG-------------SFLY 1767
Query: 397 NTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 430
+ + +++ + ST R+RSR + + +
Sbjct: 1768 QVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSS 1801
Score = 30.0 bits (66), Expect = 5.5
Identities = 42/166 (25%), Positives = 59/166 (35%), Gaps = 15/166 (9%)
Query: 297 SYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSL------AGEDDRD-SRH 349
S G+G+ GP + G++ + SE SE + S + A E RD SRH
Sbjct: 2223 SLVGQGQSS-GPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH 2281
Query: 350 QRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDAS 409
R G G S R G SS + S + S D+S
Sbjct: 2282 PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2341
Query: 410 ------ESHHSTNRRRRSRRRRTDEDAVLMDGMTE-SDTASVNENG 448
S+ R R + A +G +E SDT SV+ +G
Sbjct: 2342 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 2387
Score = 30.0 bits (66), Expect = 5.5
Identities = 45/217 (20%), Positives = 77/217 (35%), Gaps = 14/217 (6%)
Query: 280 RMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSL 339
R R + EQ R GSR R +G+G +++ S S T +
Sbjct: 3237 RNHRGSVQEQSRH-GSRHPRSHHEDR------AGHGHSADRSRQSGTRHAETSSGGQAAS 3289
Query: 340 AGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE 399
+ E R S +R R +S R G PRG SS + S+ D+
Sbjct: 3290 SHEQARSSPGERHGSRHQ----QSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEG 3345
Query: 400 SDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRA 459
+ +DT + H ++S + + + G + S V+ + A +R
Sbjct: 3346 HSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
Query: 460 ESQSRQ---RNLPRETLAKNKKEMAKDVIEEHGPSEK 493
+ RQ R++ + + +D I H S +
Sbjct: 3406 STGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 3442
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 38.5 bits (88), Expect = 0.016
Identities = 47/193 (24%), Positives = 75/193 (38%), Gaps = 34/193 (17%)
Query: 315 GTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRR------------RPGGRGR 362
G+ S +PS+ S+R D+ S + R+ RD RR R R R
Sbjct: 19 GSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDR 78
Query: 363 SVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSR 422
S R R R S S + S+P + TE + S S T+ S+
Sbjct: 79 SRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE-------NRSRSKEKTDGGESSK 131
Query: 423 RRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAK 482
++ D+D + E D + ++N L E + R+R +E + K ++E K
Sbjct: 132 EKKKDKDD--KEDEKEKDAGNFDQNKL----------EEEMRKR---KERVEKWREEQRK 176
Query: 483 DVIEEHGPSEKAI 495
+E G +K I
Sbjct: 177 KAMENIGELKKEI 189
Score = 30.0 bits (66), Expect = 5.5
Identities = 41/196 (20%), Positives = 72/196 (36%), Gaps = 31/196 (15%)
Query: 345 RDSRHQRDSRRRPGGRGRSVSGGRG---------RGGPRGGKSSISSVLKDPDSNPYSLL 395
R+SRH R +R RGRS S R RG R +S ++ +
Sbjct: 3 RESRHYR---KRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR 59
Query: 396 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 455
+ + S + RRRSR R G ++ N++
Sbjct: 60 SRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKS-------- 111
Query: 456 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQR--TP 513
++++R R+ + ++ KE KD ++ EK A D +KL+
Sbjct: 112 ---KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK------DAGNFDQNKLEEEMRK 162
Query: 514 GEEKINTLKEENTQEA 529
+E++ +EE ++A
Sbjct: 163 RKERVEKWREEQRKKA 178
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 38.1 bits (87), Expect = 0.020
Identities = 50/299 (16%), Positives = 114/299 (38%), Gaps = 43/299 (14%)
Query: 265 LLEYHIAYLKEVEQLRMERLQIDE--QLRQIGSRSYSGRGRG---RRGPNYTSGYGTNSE 319
++++ Y +++EQ R+ Q++E QLR+ + R +G R+
Sbjct: 400 MIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMA 459
Query: 320 LSNPSETESERKDE--------------------LSDWSLAGED---DRDSRHQRDSRRR 356
L +E E R D + GE+ +RD++HQ ++
Sbjct: 460 LQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGD 519
Query: 357 PGGRGRSVSGGRGRGGP--RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHS 414
PG R G P ++++ + D N + E++Q + + + +
Sbjct: 520 PGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579
Query: 415 TNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLA 474
+ + + E+ ++M G + +V+E Y AE + ++ +
Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDE-------QYQEEAEEEVQE-----DLTE 627
Query: 475 KNKKEMAKDVIEEHGPSEKAINGPTS-ASGDDISKLQRTPGEEKINTLKEENTQEAAVL 532
+ K+E+ + E +G +++ + + ++ R G E+ +EE ++ A +
Sbjct: 628 EKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAV 686
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 37.7 bits (86), Expect = 0.027
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 299 SGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPG 358
SG GRG G ++G G++S S ++ E + G+ ++ RD + G
Sbjct: 495 SGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAG 554
Query: 359 GR----GRSVSGGRGRGGPRG 375
G G+ GG G GG +G
Sbjct: 555 GHGSGGGQRPGGGHGSGGGQG 575
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 10/87 (11%)
Query: 294 GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDS 353
G SG G+G RG G G+N + S ++ + + G H
Sbjct: 518 GGNQCSGEGQGSRG-----GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG 572
Query: 354 RRRPG-----GRGRSVSGGRGRGGPRG 375
+ PG G G++ GG+G G +G
Sbjct: 573 GQGPGDGHGSGGGKNSGGGKGSGSGKG 599
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 37.7 bits (86), Expect = 0.027
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 26/129 (20%)
Query: 298 YSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRP 357
Y R RGRR P+ Y N ESERK + + SR + +SR R
Sbjct: 373 YYSRLRGRRNPSPDHSYKRNG--------ESERKSSRHRGKKSHKRTSKSRERHNSRSRG 424
Query: 358 GGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNR 417
R RS RGRG +S + + + + +S S R
Sbjct: 425 RNRDRSRDRSRGRGSRSRSRS------------------RSRRSRRSRSQSSSRSRSRGR 466
Query: 418 RRRSRRRRT 426
RR R RT
Sbjct: 467 RRSGNRDRT 475
>gi|194097341 period 1 [Homo sapiens]
Length = 1290
Score = 37.4 bits (85), Expect = 0.035
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 13/140 (9%)
Query: 279 LRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWS 338
L++ LQ++E R G+ G G GP S E TES +D LS S
Sbjct: 982 LQLNLLQLEELPRAEGAAVAGGPGSSA-GPPPPSAEAAEPEARLAEVTESSNQDALSGSS 1040
Query: 339 -----LAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNP-- 391
L ED R S G G + G G G GG +S S S+
Sbjct: 1041 DLLELLLQEDSRSGTGSAAS----GSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSK 1096
Query: 392 -YSLLDNTESDQTADTDASE 410
+ +D++E++ A +E
Sbjct: 1097 YFGSIDSSEAEAGAARGGAE 1116
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 6/67 (8%)
Query: 201 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 260
+ +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I
Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445
Query: 261 NVQVLLE 267
N Q LL+
Sbjct: 446 NAQYLLQ 452
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 37.0 bits (84), Expect = 0.045
Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 27/223 (12%)
Query: 308 PNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG 367
P + + N EL P ++SE +D + + E++ + + G + S
Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDS 315
Query: 368 RGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE-------SDQTADTDASESHHSTNRRRR 420
R + S D DS+ + ++TE SD D S S +
Sbjct: 316 ETEDASRHKQKPES----DDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK 371
Query: 421 SRRRRTDED--------------AVLMDGMTESDTASVNENGLVTVADYISRAESQSRQR 466
++ +DED AVL D E + AS ++ +V+ AD S +++ S +
Sbjct: 372 KQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDE-EKASAKKSRVVSDADD-SDSDAVSDKS 429
Query: 467 NLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKL 509
+T+A + +E A + + EK + G S SG++ L
Sbjct: 430 GKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENL 472
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 37.0 bits (84), Expect = 0.045
Identities = 61/250 (24%), Positives = 92/250 (36%), Gaps = 19/250 (7%)
Query: 272 YLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERK 331
Y + + R + + D + R+ SRS S GR R S SE N E S++
Sbjct: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR-RHESKDKSSKKHKSEEHNDKEHSSDKG 98
Query: 332 DELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG---RGRGGPRGGKSSISSVLKDPD 388
E + S GED RH+R R+ GR S S R R R K S S +
Sbjct: 99 RERLNSSENGED----RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK 154
Query: 389 SNPYSLLDNTESDQTAD-------TDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDT 441
S S ++ + S S H R RSR R D +
Sbjct: 155 SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS 214
Query: 442 ASVNENGLVTVADYISRAESQSRQRNLPR--ETLAKNKKEMAKDVIEEHGPSEKAINGPT 499
S++ + + R + Q L R E K +++ K+++E+ E A T
Sbjct: 215 RSLSRT--PSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAAT 272
Query: 500 SASGDDISKL 509
S +++ L
Sbjct: 273 GGSVLNVAAL 282
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 36.6 bits (83), Expect = 0.059
Identities = 45/210 (21%), Positives = 77/210 (36%), Gaps = 32/210 (15%)
Query: 324 SETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSV 383
+++E+ERKD DS DS + G + SG RG
Sbjct: 12 ADSEAERKDS------------DSGSDSDSDQENAASGSNASGSESDQDERGDSGQ---- 55
Query: 384 LKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA-----VLMDGMTE 438
SN D++E + + S++H + R R+D + V +E
Sbjct: 56 ----PSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSE 111
Query: 439 SDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGP 498
+ +E + S AE + + + ++K + + D ++ E+
Sbjct: 112 APNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEER---- 167
Query: 499 TSASGDDISKLQRTPGEEKI-NTLKEENTQ 527
A G D KLQ + +EK+ NT EE Q
Sbjct: 168 --AQGSDEDKLQNSDDDEKMQNTDDEERPQ 195
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 36.6 bits (83), Expect = 0.059
Identities = 57/205 (27%), Positives = 78/205 (38%), Gaps = 38/205 (18%)
Query: 283 RLQIDEQLRQIGSRSYSGRGRGR-RGPNYTSGYGTNSELSNPSETESERKDELSDWSLAG 341
R+Q+ R+ RS G RGR RG GYG S
Sbjct: 86 RVQVARYGRRDLPRSRQGEPRGRSRG----GGYGRRSRSYG------------------- 122
Query: 342 EDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDS------NPYSLL 395
R SR R R R RG S S R R RG + S S + P S +PYS
Sbjct: 123 ---RRSRSPR-RRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRS 178
Query: 396 DNTESDQTADTDASESHHSTNRRRR---SRRRRTDEDAVLMDGMTESDTASVNENGLVTV 452
ES + + S S +S +R R SR + + S ++S + +V
Sbjct: 179 RYRES-RYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSV 237
Query: 453 ADYISRAESQSRQRNLPRETLAKNK 477
+ SR+ S S R+ PR + K+K
Sbjct: 238 SRSRSRSRSSSMTRSPPRVSKRKSK 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,797,462
Number of Sequences: 37866
Number of extensions: 918380
Number of successful extensions: 5085
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 4341
Number of HSP's gapped (non-prelim): 751
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.