BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|61835148 fragile X mental retardation-related protein 1 isoform a [Homo sapiens] (621 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|61835148 fragile X mental retardation-related protein 1 isofo... 1237 0.0 gi|61835164 fragile X mental retardation-related protein 1 isofo... 1071 0.0 gi|61835172 fragile X mental retardation-related protein 1 isofo... 1059 0.0 gi|4758410 fragile X mental retardation syndrome related protein... 734 0.0 gi|4503765 fragile X mental retardation 1 [Homo sapiens] 508 e-144 gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04 gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04 gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 44 3e-04 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 43 0.001 gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 43 0.001 gi|17402900 far upstream element-binding protein [Homo sapiens] 42 0.002 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.006 gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 40 0.006 gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.008 gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 40 0.008 gi|239048862 checkpoint with forkhead and ring finger domains is... 39 0.011 gi|239048792 checkpoint with forkhead and ring finger domains is... 39 0.011 gi|52426743 cisplatin resistance-associated overexpressed protei... 39 0.011 gi|19923485 cisplatin resistance-associated overexpressed protei... 39 0.011 gi|60097902 filaggrin [Homo sapiens] 39 0.019 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 39 0.019 gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 38 0.024 gi|4504733 insulin receptor substrate 4 [Homo sapiens] 38 0.032 gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 38 0.032 gi|194097341 period 1 [Homo sapiens] 37 0.041 gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 37 0.054 gi|217330641 IWS1 homolog [Homo sapiens] 37 0.054 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 37 0.054 gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 37 0.071 gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 37 0.071 >gi|61835148 fragile X mental retardation-related protein 1 isoform a [Homo sapiens] Length = 621 Score = 1237 bits (3201), Expect = 0.0 Identities = 621/621 (100%), Positives = 621/621 (100%) Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS Sbjct: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60 Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT Sbjct: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120 Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR Sbjct: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180 Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN Sbjct: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240 Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN Sbjct: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300 Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE Sbjct: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360 Query: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS Sbjct: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420 Query: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL Sbjct: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480 Query: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 540 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY Sbjct: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 540 Query: 541 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGE 600 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGE Sbjct: 541 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGE 600 Query: 601 EKINTLKEENTQEAAVLNGVS 621 EKINTLKEENTQEAAVLNGVS Sbjct: 601 EKINTLKEENTQEAAVLNGVS 621 >gi|61835164 fragile X mental retardation-related protein 1 isoform b [Homo sapiens] Length = 539 Score = 1071 bits (2769), Expect = 0.0 Identities = 534/534 (100%), Positives = 534/534 (100%) Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS Sbjct: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60 Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT Sbjct: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120 Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR Sbjct: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180 Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN Sbjct: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240 Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN Sbjct: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300 Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE Sbjct: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE 360 Query: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS Sbjct: 361 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS 420 Query: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL Sbjct: 421 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL 480 Query: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL Sbjct: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL 534 >gi|61835172 fragile X mental retardation-related protein 1 isoform c [Homo sapiens] Length = 536 Score = 1059 bits (2739), Expect = 0.0 Identities = 536/536 (100%), Positives = 536/536 (100%) Query: 86 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 145 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN Sbjct: 1 MMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN 60 Query: 146 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 205 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA Sbjct: 61 AHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEA 120 Query: 206 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 265 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY Sbjct: 121 TKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIY 180 Query: 266 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 325 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK Sbjct: 181 GESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENK 240 Query: 326 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 385 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG Sbjct: 241 LPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSG 300 Query: 386 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 445 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR Sbjct: 301 RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR 360 Query: 446 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 505 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR Sbjct: 361 GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRR 420 Query: 506 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 565 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM Sbjct: 421 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM 480 Query: 566 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 621 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS Sbjct: 481 AKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 536 >gi|4758410 fragile X mental retardation syndrome related protein 2 [Homo sapiens] Length = 673 Score = 734 bits (1896), Expect = 0.0 Identities = 409/696 (58%), Positives = 478/696 (68%), Gaps = 114/696 (16%) Query: 4 LTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGD 63 L VEVRGSNGAFYKGF+KDVHEDS+T+ FENNWQ ERQ+PF +VRLPPP D KEI+EGD Sbjct: 14 LPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLPPPADYNKEITEGD 73 Query: 64 EVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKK 123 EVEVYSRAN+QEPCGWWLA+VRMMKG+FYVIEYAACDATYNEIVT ERLRPVN N K Sbjct: 74 EVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLERLRPVNPNPLATK 133 Query: 124 NTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNI 183 +FFK T+ VPEDLREAC+NEN HK+FKKA+GA IF + ++L ILS +EA VKR ++ Sbjct: 134 GSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFILSTTEAPVKRASL 193 Query: 184 LSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQ 243 L DMH RS+RTKL+LMSRNEEATKHLE +KQLAAAF EEF VREDLMGLAIGTHG+NIQQ Sbjct: 194 LGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQ 253 Query: 244 ARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKV 303 ARKVPGVTAIEL E+T TFRIYGE+ +A ++AR +LEF ED +QVPRNLVGKVIGKNGKV Sbjct: 254 ARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKV 313 Query: 304 IQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQ 363 IQEIVDKSGVVRVR+EGDN+ K PRE+GMVPF+FVGT+E+I N Q LLEYH++YL+EVEQ Sbjct: 314 IQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQ 373 Query: 364 LRMERLQIDEQLRQIG------------------------------------SRSYSGRG 387 LR+ERLQIDEQLRQIG SY GRG Sbjct: 374 LRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRG 433 Query: 388 RGRR--GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD-SRHQRDSRRRPGG 444 RGRR GP YG +S++S SETESE+++E + AG DRD +SRRRP Sbjct: 434 RGRRTGGP----AYGPSSDVSTASETESEKREEP---NRAGPGDRDPPTRGEESRRRP-- 484 Query: 445 RGRSVSGGRGRGGP-------RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESH 497 +GGRGRG P R SSISSVLKDPDSNPYSLLD +E + D++ E Sbjct: 485 -----TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPP 539 Query: 498 HSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGL----------------------- 534 ++ RRRRSRRRRTDED +MDG ESD ++ ENGL Sbjct: 540 PASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRNRSRRRRNRGNRTD 599 Query: 535 ---------VTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTS 585 VTVADYISRAESQSRQ +E PSE +++G Sbjct: 600 GSISGDRQPVTVADYISRAESQSRQ----------------SAPLERTKPSEDSLSG--- 640 Query: 586 ASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS 621 GD +SKL + P E N + +++NGVS Sbjct: 641 QKGDSVSKLPKGPSE---NGELSAPLELGSMVNGVS 673 >gi|4503765 fragile X mental retardation 1 [Homo sapiens] Length = 632 Score = 508 bits (1307), Expect = e-144 Identities = 247/334 (73%), Positives = 283/334 (84%) Query: 1 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS 60 M EL VEVRGSNGAFYK F+KDVHEDS+TV FENNWQP+RQ+PF++VR PPP K+I+ Sbjct: 1 MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDIN 60 Query: 61 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT 120 E DEVEVYSRAN++EPC WWLAKVRM+KGEFYVIEYAACDATYNEIVT ERLR VN NK Sbjct: 61 ESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKP 120 Query: 121 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR 180 K+TF K +DVPEDLR+ CA E AHKDFKKAVGA + Y PE QL+ILS +E T KR Sbjct: 121 ATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKR 180 Query: 181 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN 240 ++L DMH RS+RTKL L+ RNEEA+K LE ++QLA+ FHE+F+VREDLMGLAIGTHG+N Sbjct: 181 AHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGAN 240 Query: 241 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN 300 IQQARKVPGVTAI+LDEDT TF IYGE DAVKKAR FLEF ED IQVPRNLVGKVIGKN Sbjct: 241 IQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKN 300 Query: 301 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVP 334 GK+IQEIVDKSGVVRVRIE +NE +P+E+ ++P Sbjct: 301 GKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMP 334 Score = 162 bits (409), Expect = 1e-39 Identities = 132/350 (37%), Positives = 166/350 (47%), Gaps = 74/350 (21%) Query: 219 FHEEFV-VREDLMGLAIGTHGSNIQQARKVPGVTAIELDED------------------T 259 F E+ + V +L+G IG +G IQ+ GV + ++ + + Sbjct: 281 FAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPS 340 Query: 260 GTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIE 319 R+ G +A KK E F Q N +Q ++ S VV Sbjct: 341 NNSRV-GPNAPEEKKHLDIKENSTHFSQ-----------PNSTKVQRVLVASSVVA---- 384 Query: 320 GDNEN-KLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQI 378 G+++ +L GMVPFVFVGTK+SI N VLL+YH+ YLKEV+QLR+ERLQIDEQLRQI Sbjct: 385 GESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQI 444 Query: 379 ---------------------------GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSET 411 GSR Y RG GRRGP YTS GTNSE SN SET Sbjct: 445 GASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTS--GTNSEASNASET 502 Query: 412 ESERKDELSDWSLA-GEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLK 470 ES+ +DELSDWSLA E++R+S +R RR GG GR GGRGRGG G S Sbjct: 503 ESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRG-QGGRGRGGGFKGNDDHSRTDN 561 Query: 471 DPDSNPYSLLDNTESDQ---TADTDASESHHS---TNRRRRSRRRRTDED 514 P NP T D + S H+ N R RT +D Sbjct: 562 RP-RNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKD 610 >gi|145312259 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%) Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279 E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ + Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115 Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326 V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168 >gi|145312270 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%) Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279 E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ + Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115 Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326 V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168 >gi|145312256 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 10/114 (8%) Query: 222 EFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVK--KARGFL 279 E V ++ + L IG G+NI+Q RK G ED G R+ S V+ KA+ + Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115 Query: 280 EF-------VEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL 326 V + + VP+ VG++IG+ G+ I+ I SG ++ + ++E L Sbjct: 116 HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASG-AKITCDKESEGTL 168 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/184 (21%), Positives = 72/184 (39%), Gaps = 18/184 (9%) Query: 402 NSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGR-----------SVS 450 + + N + ++ K + +RDS+H R+ +R R + S Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504 Query: 451 GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTA-----DTDASESHHSTNRRRR 505 +G+ R +S S + SN + + E D+ A + D ++ HS N R R Sbjct: 505 DSKGKDQER-SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563 Query: 506 SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNL-PRETLAKNKKE 564 R R D + + D + E +Y R S+SR+R P + +K+++ Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623 Query: 565 MAKD 568 +D Sbjct: 624 RRRD 627 >gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] Length = 1303 Score = 42.7 bits (99), Expect = 0.001 Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 33/135 (24%) Query: 357 YLKEVEQLRMERLQIDEQLRQIGSRS----YSGRG-----RGRRGPNYTSGYGTNSELSN 407 + KE+ Q R + + R GSR Y GRG RGR + G G S + Sbjct: 220 FTKELNQYRRAK---EGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGD 276 Query: 408 PSETESERKDELSDWSLA----GEDDRDS--------RHQRDSRRR---------PGGRG 446 E E + +E D+ + G+DD D R +DSR R GRG Sbjct: 277 HPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGRG 336 Query: 447 RSVSGGRGRGGPRGG 461 + + GRGRGG RGG Sbjct: 337 KGMGRGRGRGGSRGG 351 Score = 32.7 bits (73), Expect = 1.0 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 12/113 (10%) Query: 410 ETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRG--------- 460 E E K++ D++ R ++ R GRGR G RGG RG Sbjct: 208 EEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRG 267 Query: 461 -GKSSISSVLKDPDSNPY-SLLDNTESDQ-TADTDASESHHSTNRRRRSRRRR 510 G+ S+ + + + Y +D ES++ D D E N+ RRS+ R Sbjct: 268 RGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSR 320 >gi|17402900 far upstream element-binding protein [Homo sapiens] Length = 644 Score = 41.6 bits (96), Expect = 0.002 Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 48/205 (23%) Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDE---DTGT---FRIYGES------ 268 +E ++ GL IG G I+Q ++ GV + + + +TG RI G+ Sbjct: 188 QEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQA 247 Query: 269 ----ADAVKKARGFLEFVEDF-----------IQVPRNLVGKVIGKNGKVIQEIVDKSGV 313 + ++ GF E ++ + +PR VG VIG+NG++I++I + +G Sbjct: 248 KEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAG- 306 Query: 314 VRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDE 373 VR++ + D DG P Q E L+ V Sbjct: 307 VRIQFKPD--------DGTTPERIAQITGPPDRCQHAAEIITDLLRSV------------ 346 Query: 374 QLRQIGSRSYSGRGRGRRGPNYTSG 398 Q G GRGRGR N+ G Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMG 371 Score = 37.7 bits (86), Expect = 0.032 Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 24/135 (17%) Query: 213 KQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFR----IYGES 268 +Q + EE+ V + ++G IG G I + ++ G I++ D+G + + Sbjct: 95 QQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCK-IQIAPDSGGLPERSCMLTGT 153 Query: 269 ADAVKKARGFLEFVEDF-------------------IQVPRNLVGKVIGKNGKVIQEIVD 309 ++V+ A+ L+ + + I +P + G VIGK G+ I+++ + Sbjct: 154 PESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQE 213 Query: 310 KSGVVRVRIEGDNEN 324 ++GV V I+ +N Sbjct: 214 RAGVKMVMIQDGPQN 228 Score = 32.0 bits (71), Expect = 1.7 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 277 GFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFV 336 G EF +FI VP G +IGK G+ I+ I +SG RIE + M F Sbjct: 375 GLQEF--NFI-VPTGKTGLIIGKGGETIKSISQQSG---ARIELQRNPPPNADPNMKLFT 428 Query: 337 FVGTKESIGNVQVLLEYHI 355 GT + I + L+E I Sbjct: 429 IRGTPQQIDYARQLIEEKI 447 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 40.0 bits (92), Expect = 0.006 Identities = 48/248 (19%), Positives = 92/248 (37%), Gaps = 5/248 (2%) Query: 372 DEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRD 431 D++ Q + S G N S ++S + S E KD + G +D D Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSR-GDASYNSDESKDNGNGSDSKGAEDDD 514 Query: 432 SRHQRDSRRRPG-GRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTAD 490 S D+ G G + + + GKS S SN D+++SD + Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574 Query: 491 TDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTA-SVNENGLVTVADYISRAESQSR 549 +S+S S + S + + + D SD++ S + + S++ES S Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634 Query: 550 QRNLPRETLAKNKKEMA--KDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLK 607 + ++ N + + D + S + + +S S D S + + ++ Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694 Query: 608 EENTQEAA 615 N+ E++ Sbjct: 695 SSNSSESS 702 Score = 37.7 bits (86), Expect = 0.032 Identities = 38/223 (17%), Positives = 78/223 (34%), Gaps = 2/223 (0%) Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455 +S +S+ SN S++ S S D DS + DS S S Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811 Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 S +S S+ ++++S ++D+ S+NR S + + + Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871 Query: 516 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 575 + SD++ NE+ +D + S + + + + D E Sbjct: 872 DSSNSSDSSDSSDSNESS--NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929 Query: 576 SEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLN 618 S+ + + +S S D + + N+ N+ +++ N Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972 Score = 37.7 bits (86), Expect = 0.032 Identities = 39/224 (17%), Positives = 87/224 (38%), Gaps = 14/224 (6%) Query: 394 NYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGR 453 N +S +S+ SN S+++S SD S DS + DS S S Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSS-------DSSNSSDSSESSNSSDNSNSSDS 938 Query: 454 GRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDE 513 S S+ +S+ D++ S ++D+++S+S S+N S + + Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993 Query: 514 DAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEM--AKDVIE 571 + D SD++ +++ + + S + S + + + + + + D + Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053 Query: 572 EHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 615 S+ + + +S S D + E ++ N+ +++ Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097 Score = 37.0 bits (84), Expect = 0.054 Identities = 40/219 (18%), Positives = 83/219 (37%), Gaps = 4/219 (1%) Query: 401 TNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRDSRRRPGGRGRSVSGGRGRGGP 458 ++S+ S+ S+++S SD S + + D DS DS+ S + Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642 Query: 459 RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLM 518 SS SS D + S + SD + +D+S S S+N S + + Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702 Query: 519 DG--MTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPS 576 D ++SD++ +++ +D S S S + ++ + + D + S Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762 Query: 577 EKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 615 + + +S S D + + N+ ++ ++ Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801 Score = 36.6 bits (83), Expect = 0.071 Identities = 39/195 (20%), Positives = 70/195 (35%), Gaps = 1/195 (0%) Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455 +S +S+ S+ S++ S S D DS DS S S Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152 Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 S S DS+ S N+ SD + +D+S+S S++ S + + + Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211 Query: 516 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 575 D SD++ +++ + S + S N + + + + D +E Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDS 1271 Query: 576 SEKAINGPTSASGDD 590 K+ NG + S D Sbjct: 1272 QSKSGNGNNNGSDSD 1286 Score = 35.8 bits (81), Expect = 0.12 Identities = 39/197 (19%), Positives = 73/197 (37%), Gaps = 20/197 (10%) Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455 +S +SE S+ S++ + SD S + D DS + DS S Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS------- 744 Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 SS SS D + S + SD + +D+S+S +S++ S + + + Sbjct: 745 ------DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798 Query: 516 VLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGP 575 D SD++ +++ S + + S N + + N + + G Sbjct: 799 NSSDSSNSSDSSDSSDSS-------DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851 Query: 576 SEKAINGPTSASGDDIS 592 + N S++ D S Sbjct: 852 DSDSSNRSDSSNSSDSS 868 Score = 35.0 bits (79), Expect = 0.21 Identities = 33/157 (21%), Positives = 65/157 (41%), Gaps = 4/157 (2%) Query: 380 SRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGE--DDRDSRHQRD 437 S S + + + +S + S+ S+ + ++S + SD S + D DS D Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676 Query: 438 SRRRPGGRGRSVSGGRG--RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASE 495 S S S SS SS DS+ S ++++SD + +D+S+ Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736 Query: 496 SHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 532 S +S++ S + + + D SD++ +++ Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773 Score = 34.7 bits (78), Expect = 0.27 Identities = 42/221 (19%), Positives = 77/221 (34%), Gaps = 6/221 (2%) Query: 397 SGYGTNSELSNPSETESERKDEL-SDWSLAGEDDRDSRHQRDS-RRRPGGRGRSVSGGRG 454 S +NS SN S S+ D S S D DS DS S Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835 Query: 455 RGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDED 514 SS SS D DS+ S S+ + +D+S+S +S++ S + Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRS----DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891 Query: 515 AVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHG 574 + D SD+ S + + +D + ++S + + + + Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 575 PSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 615 S + N S++ D S + + N+ ++ +++ Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Score = 33.9 bits (76), Expect = 0.46 Identities = 40/221 (18%), Positives = 79/221 (35%), Gaps = 2/221 (0%) Query: 397 SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRG 456 S G++S+ SN S++ + S S D DS +S S S Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906 Query: 457 -GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 SS SS D + S ++ SD + +D+S+S S+N S + + Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966 Query: 516 VLMDGMTESDTASVNENGLVTVADYISRAE-SQSRQRNLPRETLAKNKKEMAKDVIEEHG 574 D + + S N + +D ++ S S + ++ + + D Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026 Query: 575 PSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 615 S + + +S S D + + N+ ++ +++ Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067 Score = 33.9 bits (76), Expect = 0.46 Identities = 42/224 (18%), Positives = 85/224 (37%), Gaps = 5/224 (2%) Query: 394 NYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGR 453 N + +NS S+ S S+ D S S D DS + DS S S Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSD--SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021 Query: 454 GRGGPRGGKSSISSVLKDPDSNPYS-LLDNTESDQTADT-DASESHHSTNRRRRSRRRRT 511 S S DS+ S D+++S ++D+ D+S+S S++ S + Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081 Query: 512 DEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIE 571 E + D SD++ +++ + + S + S N + + + + + D Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-SSDSSN 1140 Query: 572 EHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAA 615 S+ + + +S S D + + ++ N+ +++ Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184 Score = 29.6 bits (65), Expect = 8.6 Identities = 37/150 (24%), Positives = 54/150 (36%), Gaps = 27/150 (18%) Query: 396 TSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGR 455 +S +S+ SN S++ S S D DS DS Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS----------------- 1210 Query: 456 GGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 SS SS D + S N SD + +D+S+S +S++ S D Sbjct: 1211 -----SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS-----DSSD 1260 Query: 516 VLMDGMTESDTASVNENGLVTVADYISRAE 545 D ESD+ S + NG +D S +E Sbjct: 1261 STSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290 >gi|100816392 far upstream element (FUSE) binding protein 3 [Homo sapiens] Length = 572 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 29/130 (22%) Query: 221 EEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDED---TGT---FRIYGESADAVKK 274 +E ++ +GL IG G I+Q ++ GV + + + TG RI G++ + Sbjct: 165 QEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQA 224 Query: 275 ARGFLEFVE------------DF----------IQVPRNLVGKVIGKNGKVIQEIVDKSG 312 LE + DF + VPR VG VIG+NG++I++I + +G Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAG 284 Query: 313 VVRVRIEGDN 322 VR++ + D+ Sbjct: 285 -VRIQFKPDD 293 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 7/69 (10%) Query: 283 EDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKE 342 E+F +VP +VG +IG+ G+ I I +SG +++I ++ R P V GT E Sbjct: 80 EEF-KVPDKMVGFIIGRGGEQISRIQAESG-CKIQIASESSGIPER-----PCVLTGTPE 132 Query: 343 SIGNVQVLL 351 SI + LL Sbjct: 133 SIEQAKRLL 141 >gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%) Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345 + +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445 Query: 346 NVQVLLEYHIAYLKEVE 362 N Q LL+ + +VE Sbjct: 446 NAQYLLQNSVKQYADVE 462 >gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 6/77 (7%) Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345 + +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445 Query: 346 NVQVLLEYHIAYLKEVE 362 N Q LL+ + +VE Sbjct: 446 NAQYLLQNSVKQYADVE 462 >gi|239048862 checkpoint with forkhead and ring finger domains isoform 2 [Homo sapiens] Length = 663 Score = 39.3 bits (90), Expect = 0.011 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%) Query: 299 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 358 K+G+V E SG V +++ + P + G V ++ E NV L E L Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123 Query: 359 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 418 E + + E + +++ G++ SG G GR G + + PS ++ E Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173 Query: 419 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 467 S + D + + P GR RS S G G GG P+G S++S Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224 >gi|239048792 checkpoint with forkhead and ring finger domains isoform 1 [Homo sapiens] Length = 664 Score = 39.3 bits (90), Expect = 0.011 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 16/171 (9%) Query: 299 KNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYL 358 K+G+V E SG V +++ + P + G V ++ E NV L E L Sbjct: 68 KSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYES----L 123 Query: 359 KEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDE 418 E + + E + +++ G++ SG G GR G + + PS ++ E Sbjct: 124 SEKQGMTQESFEANKENVFHGTKDTSGAGAGR---------GADPRVP-PSSPATQVCFE 173 Query: 419 LSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGG--PRGGKSSISS 467 S + D + + P GR RS S G G GG P+G S++S Sbjct: 174 EPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVAS 224 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 39.3 bits (90), Expect = 0.011 Identities = 67/329 (20%), Positives = 116/329 (35%), Gaps = 36/329 (10%) Query: 298 GKNGKVIQEIVDKSGVVRVRIEG-DNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIA 356 GKN + IQ + DK V+ +IE +E K+ GM+ V E + + LL + Sbjct: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV-----EQLKEERELLRSTTS 177 Query: 357 YLKE--VEQLRMERLQIDEQLRQIGSRS--YSGRGRGRRGPNYTSGYGTNSELSNPSETE 412 ++ ++ +ME ++ +G G++ Y T EL Sbjct: 178 TIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKR 237 Query: 413 SERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDP 472 +E D E + + +R+ R + R R R R R + +D Sbjct: 238 TEEPDR-------DERLKKEKQEREEREKEREREREE---RERKRRREEEEREKERARDR 287 Query: 473 DSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 532 + S + S +T+D S S R R RRR D S+ Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK----- 342 Query: 533 GLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDIS 592 R+ S+ R+R+ R+ + + ++D ++ EK G S Sbjct: 343 ---------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393 Query: 593 KLQRTPGEEKINTLKEENTQEAAVLNGVS 621 + E+ KE +T+ +NG S Sbjct: 394 GSREKQSEDTNTESKESDTKNE--VNGTS 420 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 39.3 bits (90), Expect = 0.011 Identities = 67/329 (20%), Positives = 116/329 (35%), Gaps = 36/329 (10%) Query: 298 GKNGKVIQEIVDKSGVVRVRIEG-DNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIA 356 GKN + IQ + DK V+ +IE +E K+ GM+ V E + + LL + Sbjct: 123 GKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV-----EQLKEERELLRSTTS 177 Query: 357 YLKE--VEQLRMERLQIDEQLRQIGSRS--YSGRGRGRRGPNYTSGYGTNSELSNPSETE 412 ++ ++ +ME ++ +G G++ Y T EL Sbjct: 178 TIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKR 237 Query: 413 SERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDP 472 +E D E + + +R+ R + R R R R R + +D Sbjct: 238 TEEPDR-------DERLKKEKQEREEREKEREREREE---RERKRRREEEEREKERARDR 287 Query: 473 DSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNEN 532 + S + S +T+D S S R R RRR D S+ Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK----- 342 Query: 533 GLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDIS 592 R+ S+ R+R+ R+ + + ++D ++ EK G S Sbjct: 343 ---------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKS 393 Query: 593 KLQRTPGEEKINTLKEENTQEAAVLNGVS 621 + E+ KE +T+ +NG S Sbjct: 394 GSREKQSEDTNTESKESDTKNE--VNGTS 420 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 38.5 bits (88), Expect = 0.019 Identities = 61/262 (23%), Positives = 98/262 (37%), Gaps = 44/262 (16%) Query: 375 LRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETES---ERKDELSDWSLAGEDDRD 431 L Q+ + S GR GP+ G+ E + S S E +D + + R Sbjct: 3711 LYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770 Query: 432 SRHQRDSRRRPG--GRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTES---D 486 + S R G G S + +GR G+S S ++ + S + S Sbjct: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRH 3830 Query: 487 QTADTDASESHHSTNRRRR---SRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISR 543 A T A S HS + + SRR R +V D SD+ + E D R Sbjct: 3831 HEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD----SDSEAYPE-------DSERR 3879 Query: 544 AESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKI 603 +ES SR + + +E ++D G S + D S +Q +P + Sbjct: 3880 SESASRNHH-------GSSREQSRDGSRHPGSSHR----------DTASHVQSSPVQSDS 3922 Query: 604 NTLKEEN-----TQEAAVLNGV 620 +T KE +Q++A +G+ Sbjct: 3923 STAKEHGHFSSLSQDSAYHSGI 3944 Score = 35.0 bits (79), Expect = 0.21 Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 24/154 (15%) Query: 362 EQLRMERLQIDEQLRQIGSRSYSGRGRG-RRGPNYTSGYGTNSEL-SNPSETESERKDEL 419 EQ R Q Q R + G RG R+G +Y ++ S+ S T S+ + ++ Sbjct: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDV 1854 Query: 420 S--------------DWSLAGEDDRDS--RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKS 463 S + +G+ R S RH S R R V G+ GPR ++ Sbjct: 1855 SRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQS-SGPRTSRN 1913 Query: 464 SISSVLKDPDSNPYSLLDNTESDQTADTDASESH 497 SSV +D DS +S E + AS +H Sbjct: 1914 QGSSVSQDSDSQGHS-----EDSERWSGSASRNH 1942 Score = 33.1 bits (74), Expect = 0.78 Identities = 44/177 (24%), Positives = 62/177 (35%), Gaps = 16/177 (9%) Query: 373 EQLRQIGSRSYSGRGRGRR-GPNYTSGYGTNSELSNPSETESERKDELSDWSL------A 425 E Q S +S G+G+ GP + G++ + S+ SE + S + A Sbjct: 590 EASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA 649 Query: 426 GEDDRD-SRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE 484 E RD SRH R G G S R G SS + S + Sbjct: 650 QEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHG 709 Query: 485 SDQTADTDASESHHSTNR-------RRRSRRRRTDEDAVLMDGMTE-SDTASVNENG 533 S + S H T R R + A +G +E SDT SV+ +G Sbjct: 710 SRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHG 766 Score = 33.1 bits (74), Expect = 0.78 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 24/145 (16%) Query: 389 GRRGPNYT-----SGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPG 443 GR+G +Y SG+ + S+ S+ S A R+ D R G Sbjct: 2472 GRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSG 2531 Query: 444 GRGRSVSG----------GRGRG-GPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTD 492 R S G+G+ GPR ++ SS +D DS +S E + Sbjct: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHS-----EDSERWSGS 2586 Query: 493 ASESHHSTNR---RRRSRRRRTDED 514 AS +HH + + R SR R+ ++ Sbjct: 2587 ASRNHHGSAQEQLRDGSRHPRSHQE 2611 Score = 32.0 bits (71), Expect = 1.7 Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 14/241 (5%) Query: 380 SRSYSG--RGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRD 437 S +SG RG+ + +G++ ++ SE SE D S HQ Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQES 3371 Query: 438 SRRRPGGR-GRSVS-----GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADT 491 +R R GGR GRS S + G++ S+ + + + + S Sbjct: 3372 ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 3431 Query: 492 DASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQR 551 D H ++ RR R+ E +V G + S + G + S + S SRQ Sbjct: 3432 DTIRGHPGSS--RRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489 Query: 552 NLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENT 611 ++ ++ + H S +A + S SG S RT + + ++ ++ Sbjct: 3490 RNDEQSGDGSRHSWS----HHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS 3545 Query: 612 Q 612 Q Sbjct: 3546 Q 3546 Score = 31.2 bits (69), Expect = 3.0 Identities = 36/155 (23%), Positives = 56/155 (36%), Gaps = 29/155 (18%) Query: 370 QIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELS---------NPSETESERKDELS 420 Q + R S+ RG GP+ G++ E S + S T S+ + + S Sbjct: 2121 QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDAS 2180 Query: 421 --------------DWSLAGEDDRDS-RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSI 465 D +G+ R S H ++ S+ G GPR + Sbjct: 2181 RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRG 2240 Query: 466 SSVLKDPDSNPYSLLDNTESDQTADTDASESHHST 500 SSV +D DS +S E + AS +HH + Sbjct: 2241 SSVSQDSDSEGHS-----EDSERRSGSASRNHHGS 2270 Score = 30.8 bits (68), Expect = 3.9 Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 15/163 (9%) Query: 379 GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDS 438 GSR+ +G + + G+ +SE + S + + R S + SRH R Sbjct: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG------SAQEQSRHGSRHPRSH 988 Query: 439 RRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHH 498 G G S R G P SS + S + S D+S H Sbjct: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSR-HS 1047 Query: 499 STNRRRRSRRRR-------TDEDAVLMDGMT-ESDTASVNENG 533 RR+ S R + A +G + ESDT SV+ +G Sbjct: 1048 GIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHG 1090 Score = 30.8 bits (68), Expect = 3.9 Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 24/157 (15%) Query: 362 EQLRMERLQIDEQLRQIGSRSYSGRGR-GRRGPNY----------------TSGYGTNSE 404 EQ R Q Q R + G R GR+G +Y T+ G + Sbjct: 3416 EQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475 Query: 405 LSNPSETESERKDELSDWSLAGEDDRDS-RHQRDSRRRPGGRGRSVSGGRGRGGPRGGKS 463 S + S + +D +G+ R S H ++ + S SG GPR ++ Sbjct: 3476 SRGQSGSRSASRQTRND-EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRN 3534 Query: 464 SISSVLKDPDSNPYSLLDNTESDQTADTDASESHHST 500 SSV +D DS +S E + AS +H + Sbjct: 3535 QGSSVSQDSDSQGHS-----EDSERWSGSASRNHRGS 3566 Score = 30.0 bits (66), Expect = 6.6 Identities = 33/154 (21%), Positives = 54/154 (35%), Gaps = 23/154 (14%) Query: 362 EQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSD 421 EQ R + Q + S + G GRR + G N S ++SE E SD Sbjct: 1671 EQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESD 1730 Query: 422 WSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLD 481 + HQ+ + RG+ G R G+S S L Sbjct: 1731 TQSVSAHGQAGPHQQSHQ----------ESTRGQSGERSGRSG-------------SFLY 1767 Query: 482 NTESDQTADTDASESHHSTNRRRRSRRRRTDEDA 515 + + +++ + ST R+RSR + + + Sbjct: 1768 QVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSS 1801 Score = 30.0 bits (66), Expect = 6.6 Identities = 42/166 (25%), Positives = 59/166 (35%), Gaps = 15/166 (9%) Query: 382 SYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSL------AGEDDRD-SRH 434 S G+G+ GP + G++ + SE SE + S + A E RD SRH Sbjct: 2223 SLVGQGQSS-GPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH 2281 Query: 435 QRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDAS 494 R G G S R G SS + S + S D+S Sbjct: 2282 PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2341 Query: 495 ------ESHHSTNRRRRSRRRRTDEDAVLMDGMTE-SDTASVNENG 533 S+ R R + A +G +E SDT SV+ +G Sbjct: 2342 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 2387 Score = 30.0 bits (66), Expect = 6.6 Identities = 45/217 (20%), Positives = 77/217 (35%), Gaps = 14/217 (6%) Query: 365 RMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSL 424 R R + EQ R GSR R +G+G +++ S S T + Sbjct: 3237 RNHRGSVQEQSRH-GSRHPRSHHEDR------AGHGHSADRSRQSGTRHAETSSGGQAAS 3289 Query: 425 AGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE 484 + E R S +R R +S R G PRG SS + S+ D+ Sbjct: 3290 SHEQARSSPGERHGSRHQ----QSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEG 3345 Query: 485 SDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRA 544 + +DT + H ++S + + + G + S V+ + A +R Sbjct: 3346 HSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405 Query: 545 ESQSRQ---RNLPRETLAKNKKEMAKDVIEEHGPSEK 578 + RQ R++ + + +D I H S + Sbjct: 3406 STGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 3442 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 38.5 bits (88), Expect = 0.019 Identities = 47/193 (24%), Positives = 75/193 (38%), Gaps = 34/193 (17%) Query: 400 GTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRR------------RPGGRGR 447 G+ S +PS+ S+R D+ S + R+ RD RR R R R Sbjct: 19 GSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDR 78 Query: 448 SVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSR 507 S R R R S S + S+P + TE + S S T+ S+ Sbjct: 79 SRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE-------NRSRSKEKTDGGESSK 131 Query: 508 RRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAK 567 ++ D+D + E D + ++N L E + R+R +E + K ++E K Sbjct: 132 EKKKDKDD--KEDEKEKDAGNFDQNKL----------EEEMRKR---KERVEKWREEQRK 176 Query: 568 DVIEEHGPSEKAI 580 +E G +K I Sbjct: 177 KAMENIGELKKEI 189 Score = 30.0 bits (66), Expect = 6.6 Identities = 41/196 (20%), Positives = 72/196 (36%), Gaps = 31/196 (15%) Query: 430 RDSRHQRDSRRRPGGRGRSVSGGRG---------RGGPRGGKSSISSVLKDPDSNPYSLL 480 R+SRH R +R RGRS S R RG R +S ++ + Sbjct: 3 RESRHYR---KRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR 59 Query: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 540 + + S + RRRSR R G ++ N++ Sbjct: 60 SRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKS-------- 111 Query: 541 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQR--TP 598 ++++R R+ + ++ KE KD ++ EK A D +KL+ Sbjct: 112 ---KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK------DAGNFDQNKLEEEMRK 162 Query: 599 GEEKINTLKEENTQEA 614 +E++ +EE ++A Sbjct: 163 RKERVEKWREEQRKKA 178 >gi|7657138 golgi integral membrane protein 4 [Homo sapiens] Length = 696 Score = 38.1 bits (87), Expect = 0.024 Identities = 50/299 (16%), Positives = 114/299 (38%), Gaps = 43/299 (14%) Query: 350 LLEYHIAYLKEVEQLRMERLQIDE--QLRQIGSRSYSGRGRG---RRGPNYTSGYGTNSE 404 ++++ Y +++EQ R+ Q++E QLR+ + R +G R+ Sbjct: 400 MIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMA 459 Query: 405 LSNPSETESERKDE--------------------LSDWSLAGED---DRDSRHQRDSRRR 441 L +E E R D + GE+ +RD++HQ ++ Sbjct: 460 LQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGD 519 Query: 442 PGGRGRSVSGGRGRGGP--RGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHS 499 PG R G P ++++ + D N + E++Q + + + + Sbjct: 520 PGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579 Query: 500 TNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLA 559 + + + E+ ++M G + +V+E Y AE + ++ + Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDE-------QYQEEAEEEVQE-----DLTE 627 Query: 560 KNKKEMAKDVIEEHGPSEKAINGPTS-ASGDDISKLQRTPGEEKINTLKEENTQEAAVL 617 + K+E+ + E +G +++ + + ++ R G E+ +EE ++ A + Sbjct: 628 EKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAV 686 >gi|4504733 insulin receptor substrate 4 [Homo sapiens] Length = 1257 Score = 37.7 bits (86), Expect = 0.032 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 384 SGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPG 443 SG GRG G ++G G++S S ++ E + G+ ++ RD + G Sbjct: 495 SGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAG 554 Query: 444 GR----GRSVSGGRGRGGPRG 460 G G+ GG G GG +G Sbjct: 555 GHGSGGGQRPGGGHGSGGGQG 575 Score = 31.6 bits (70), Expect = 2.3 Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 10/87 (11%) Query: 379 GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDS 438 G SG G+G RG G G+N + S ++ + + G H Sbjct: 518 GGNQCSGEGQGSRG-----GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG 572 Query: 439 RRRPG-----GRGRSVSGGRGRGGPRG 460 + PG G G++ GG+G G +G Sbjct: 573 GQGPGDGHGSGGGKNSGGGKGSGSGKG 599 >gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo sapiens] Length = 482 Score = 37.7 bits (86), Expect = 0.032 Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 26/129 (20%) Query: 383 YSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRP 442 Y R RGRR P+ Y N ESERK + + SR + +SR R Sbjct: 373 YYSRLRGRRNPSPDHSYKRNG--------ESERKSSRHRGKKSHKRTSKSRERHNSRSRG 424 Query: 443 GGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNR 502 R RS RGRG +S + + + + +S S R Sbjct: 425 RNRDRSRDRSRGRGSRSRSRS------------------RSRRSRRSRSQSSSRSRSRGR 466 Query: 503 RRRSRRRRT 511 RR R RT Sbjct: 467 RRSGNRDRT 475 >gi|194097341 period 1 [Homo sapiens] Length = 1290 Score = 37.4 bits (85), Expect = 0.041 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 13/140 (9%) Query: 364 LRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWS 423 L++ LQ++E R G+ G G GP S E TES +D LS S Sbjct: 982 LQLNLLQLEELPRAEGAAVAGGPGSSA-GPPPPSAEAAEPEARLAEVTESSNQDALSGSS 1040 Query: 424 -----LAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNP-- 476 L ED R S G G + G G G GG +S S S+ Sbjct: 1041 DLLELLLQEDSRSGTGSAAS----GSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSK 1096 Query: 477 -YSLLDNTESDQTADTDASE 495 + +D++E++ A +E Sbjct: 1097 YFGSIDSSEAEAGAARGGAE 1116 >gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b [Homo sapiens] Length = 463 Score = 37.0 bits (84), Expect = 0.054 Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 6/67 (8%) Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG 345 + +P++L G +IGK G+ I++I +SG ++I+ E ED ++ GT++ I Sbjct: 392 VTIPKDLAGSIIGKGGQRIKQIRHESG-ASIKIDEPLEGS---EDRII--TITGTQDQIQ 445 Query: 346 NVQVLLE 352 N Q LL+ Sbjct: 446 NAQYLLQ 452 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 37.0 bits (84), Expect = 0.054 Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 27/223 (12%) Query: 393 PNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG 452 P + + N EL P ++SE +D + + E++ + + G + S Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDS 315 Query: 453 RGRGGPRGGKSSISSVLKDPDSNPYSLLDNTE-------SDQTADTDASESHHSTNRRRR 505 R + S D DS+ + ++TE SD D S S + Sbjct: 316 ETEDASRHKQKPES----DDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK 371 Query: 506 SRRRRTDED--------------AVLMDGMTESDTASVNENGLVTVADYISRAESQSRQR 551 ++ +DED AVL D E + AS ++ +V+ AD S +++ S + Sbjct: 372 KQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDE-EKASAKKSRVVSDADD-SDSDAVSDKS 429 Query: 552 NLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKL 594 +T+A + +E A + + EK + G S SG++ L Sbjct: 430 GKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENL 472 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 37.0 bits (84), Expect = 0.054 Identities = 61/250 (24%), Positives = 92/250 (36%), Gaps = 19/250 (7%) Query: 357 YLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERK 416 Y + + R + + D + R+ SRS S GR R S SE N E S++ Sbjct: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR-RHESKDKSSKKHKSEEHNDKEHSSDKG 98 Query: 417 DELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGG---RGRGGPRGGKSSISSVLKDPD 473 E + S GED RH+R R+ GR S S R R R K S S + Sbjct: 99 RERLNSSENGED----RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK 154 Query: 474 SNPYSLLDNTESDQTAD-------TDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDT 526 S S ++ + S S H R RSR R D + Sbjct: 155 SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS 214 Query: 527 ASVNENGLVTVADYISRAESQSRQRNLPR--ETLAKNKKEMAKDVIEEHGPSEKAINGPT 584 S++ + + R + Q L R E K +++ K+++E+ E A T Sbjct: 215 RSLSRT--PSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAAT 272 Query: 585 SASGDDISKL 594 S +++ L Sbjct: 273 GGSVLNVAAL 282 >gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog [Homo sapiens] Length = 666 Score = 36.6 bits (83), Expect = 0.071 Identities = 45/210 (21%), Positives = 77/210 (36%), Gaps = 32/210 (15%) Query: 409 SETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSV 468 +++E+ERKD DS DS + G + SG RG Sbjct: 12 ADSEAERKDS------------DSGSDSDSDQENAASGSNASGSESDQDERGDSGQ---- 55 Query: 469 LKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDA-----VLMDGMTE 523 SN D++E + + S++H + R R+D + V +E Sbjct: 56 ----PSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSE 111 Query: 524 SDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGP 583 + +E + S AE + + + ++K + + D ++ E+ Sbjct: 112 APNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEER---- 167 Query: 584 TSASGDDISKLQRTPGEEKI-NTLKEENTQ 612 A G D KLQ + +EK+ NT EE Q Sbjct: 168 --AQGSDEDKLQNSDDDEKMQNTDDEERPQ 195 >gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] Length = 282 Score = 36.6 bits (83), Expect = 0.071 Identities = 57/205 (27%), Positives = 78/205 (38%), Gaps = 38/205 (18%) Query: 368 RLQIDEQLRQIGSRSYSGRGRGR-RGPNYTSGYGTNSELSNPSETESERKDELSDWSLAG 426 R+Q+ R+ RS G RGR RG GYG S Sbjct: 86 RVQVARYGRRDLPRSRQGEPRGRSRG----GGYGRRSRSYG------------------- 122 Query: 427 EDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDS------NPYSLL 480 R SR R R R RG S S R R RG + S S + P S +PYS Sbjct: 123 ---RRSRSPR-RRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRS 178 Query: 481 DNTESDQTADTDASESHHSTNRRRR---SRRRRTDEDAVLMDGMTESDTASVNENGLVTV 537 ES + + S S +S +R R SR + + S ++S + +V Sbjct: 179 RYRES-RYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSV 237 Query: 538 ADYISRAESQSRQRNLPRETLAKNK 562 + SR+ S S R+ PR + K+K Sbjct: 238 SRSRSRSRSSSMTRSPPRVSKRKSK 262 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,872,539 Number of Sequences: 37866 Number of extensions: 1126542 Number of successful extensions: 5523 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 216 Number of HSP's that attempted gapping in prelim test: 4805 Number of HSP's gapped (non-prelim): 720 length of query: 621 length of database: 18,247,518 effective HSP length: 108 effective length of query: 513 effective length of database: 14,157,990 effective search space: 7263048870 effective search space used: 7263048870 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.