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Search of human proteins with 61744454
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
sapiens]
(291 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 592 e-169
gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 586 e-168
gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 499 e-141
gi|5730019 peropsin [Homo sapiens] 132 3e-31
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 115 6e-26
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 106 2e-23
gi|38678524 opsin 5 isoform 1 [Homo sapiens] 103 2e-22
gi|71999131 opsin 3 [Homo sapiens] 102 4e-22
gi|4506527 rhodopsin [Homo sapiens] 92 7e-19
gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 68 8e-12
gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 68 8e-12
gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 67 2e-11
gi|5174593 melatonin receptor 1A [Homo sapiens] 60 2e-09
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 60 2e-09
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 60 3e-09
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 60 3e-09
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 60 3e-09
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens] 57 2e-08
gi|71999146 opsin 5 isoform 2 [Homo sapiens] 57 2e-08
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 55 6e-08
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 55 7e-08
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 54 1e-07
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 54 2e-07
gi|5174595 melatonin receptor 1B [Homo sapiens] 53 3e-07
gi|4557857 somatostatin receptor 1 [Homo sapiens] 53 3e-07
gi|7669548 tachykinin receptor 3 [Homo sapiens] 53 4e-07
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 52 5e-07
gi|4505513 opiate receptor-like 1 [Homo sapiens] 52 5e-07
gi|33286424 opiate receptor-like 1 [Homo sapiens] 52 5e-07
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 50 3e-06
>gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
sapiens]
Length = 291
Score = 592 bits (1526), Expect = e-169
Identities = 291/291 (100%), Positives = 291/291 (100%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR 120
ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR
Sbjct: 61 ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR 120
Query: 121 SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM 180
SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM
Sbjct: 121 SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM 180
Query: 181 SFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVT 240
SFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVT
Sbjct: 181 SFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVT 240
Query: 241 SISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 291
SISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 241 SISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 291
>gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
sapiens]
Length = 295
Score = 586 bits (1511), Expect = e-168
Identities = 291/295 (98%), Positives = 291/295 (98%), Gaps = 4/295 (1%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLR----RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 116
ADSGISLNALVAATSSLLR RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
Sbjct: 61 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 120
Query: 117 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 176
YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
Sbjct: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 180
Query: 177 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 236
LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
Sbjct: 181 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 240
Query: 237 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 291
ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 241 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 295
>gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo
sapiens]
Length = 253
Score = 499 bits (1284), Expect = e-141
Identities = 253/291 (86%), Positives = 253/291 (86%), Gaps = 38/291 (13%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR 120
ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR
Sbjct: 61 ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR 120
Query: 121 SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM 180
SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM
Sbjct: 121 SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM 180
Query: 181 SFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVT 240
SFFNFAMPLFITITSYSLMEQKLGKSGHLQ
Sbjct: 181 SFFNFAMPLFITITSYSLMEQKLGKSGHLQ------------------------------ 210
Query: 241 SISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 291
VPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 211 --------VPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 253
>gi|5730019 peropsin [Homo sapiens]
Length = 337
Score = 132 bits (333), Expect = 3e-31
Identities = 79/286 (27%), Positives = 134/286 (46%), Gaps = 20/286 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNA 69
F + E V L++ + + N + + F K ELRTP + ++++LA+ D G+S +
Sbjct: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
Query: 70 LVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS---QLAWN 126
++A S L W +G GCQ + +ASI +A RY C ++ N
Sbjct: 80 PMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTN 139
Query: 127 SAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFA 186
+ + L+L W++ FWA +P++GW Y +P G CT+++ K DR+F S+ T+ NF
Sbjct: 140 TYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFI 199
Query: 187 MPLFITITSY------------SLMEQKLGKSGHLQVNTT----LPARTLLLGWGPYAIL 230
+PL + Y S + L + Q++ T + L+ W PY+I+
Sbjct: 200 VPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIV 259
Query: 231 YLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGI 276
L+A D I P + ++ L AK N Y + N+ R +
Sbjct: 260 CLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAM 305
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 115 bits (287), Expect = 6e-26
Identities = 81/280 (28%), Positives = 131/280 (46%), Gaps = 31/280 (11%)
Query: 19 VGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLN-ALVAATSSL 77
+G V+L+ L+G+ N I++FC++ LRTP ++ +++LA++D +S A V TSSL
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSL 132
Query: 78 LRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQLAWNSAVSLVL 133
++W +G GC+ + F G + ++S+ + AIA RY T + A ++L
Sbjct: 133 YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLL 192
Query: 134 FVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITI 193
VWL + W+ P GW Y E L T C+ DY ++ + F F +PL I I
Sbjct: 193 GVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIII 252
Query: 194 TSYSLMEQKLGKSG--------------------HLQVNTTLPARTLL------LGWGPY 227
Y + + + ++G LQ + LL L W PY
Sbjct: 253 YCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPY 312
Query: 228 AILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 267
+ + L A ++P + VPA+IAK N I YA+
Sbjct: 313 SAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 352
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 106 bits (265), Expect = 2e-23
Identities = 81/291 (27%), Positives = 131/291 (45%), Gaps = 42/291 (14%)
Query: 19 VGMVLLVEALSGLSLNTLTIFSFCK-----------TPELRTPCHLLVLSLALADSGISL 67
+G V+L+ L+G+ N I++FC+ + LRTP ++ +++LA++D +S
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
Query: 68 N-ALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQ 122
A V TSSL ++W +G GC+ + F G + ++S+ + AIA RY T
Sbjct: 133 TQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGV 192
Query: 123 LAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSF 182
+ A ++L VWL + W+ P GW Y E L T C+ DY ++ +
Sbjct: 193 ASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCC 252
Query: 183 FNFAMPLFITITSYSLMEQKLGKSG--------------------HLQVNTTLPARTLL- 221
F F +PL I I Y + + + ++G LQ + LL
Sbjct: 253 FVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLV 312
Query: 222 -----LGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 267
L W PY+ + L A ++P + VPA+IAK N I YA+
Sbjct: 313 ILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 363
>gi|38678524 opsin 5 isoform 1 [Homo sapiens]
Length = 354
Score = 103 bits (257), Expect = 2e-22
Identities = 70/273 (25%), Positives = 120/273 (43%), Gaps = 24/273 (8%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISL-NALVAATS 75
L G L + + N ++ + + P ++ ++LA+ D GIS+ S
Sbjct: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIIS 93
Query: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---NSAVSLV 132
RW +G GC+ +G+ GF S+ + A++ RY C S W A +
Sbjct: 94 CFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICL 153
Query: 133 LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLF 190
+W ++FW +PL+G G Y EP GT CTLD+ ++ F+ + FF +P
Sbjct: 154 AAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTA 213
Query: 191 ITITSY--------------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAILYL 232
+ + SY + + ++ S L++ T A + L+ W PYA++ +
Sbjct: 214 VIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSV 273
Query: 233 YAVIADVTSISPKLQMVPALIAKMVPTINAINY 265
++ SI +L +VP L+AK N I Y
Sbjct: 274 WSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIY 306
>gi|71999131 opsin 3 [Homo sapiens]
Length = 402
Score = 102 bits (254), Expect = 4e-22
Identities = 75/290 (25%), Positives = 123/290 (42%), Gaps = 39/290 (13%)
Query: 28 LSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRR-WPYGSD 86
L G+ N L + + K LRTP HLL+++++L+D +SL + S LR W + +
Sbjct: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112
Query: 87 GCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALP 146
GC GF G + + SI + +A+ RY + ++ A + ++WL S WA P
Sbjct: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAP 172
Query: 147 LLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLM------- 199
LLGW Y + G CT+D+ D N +SF+ + +PL + Y +
Sbjct: 173 LLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML 232
Query: 200 -----------------EQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSI 242
E+KL K L + T L+ W PY ++ V +
Sbjct: 233 RCVEDLQTIQVIKILKYEKKLAKMCFLMI------FTFLVCWMPYIVICFLVVNGHGHLV 286
Query: 243 SPKLQMVPALIAKMVPTINAINYALG--------NEMVCRGIWQCLSPQK 284
+P + +V L AK N + Y +++C + +C P K
Sbjct: 287 TPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAK 336
>gi|4506527 rhodopsin [Homo sapiens]
Length = 348
Score = 91.7 bits (226), Expect = 7e-19
Identities = 73/278 (26%), Positives = 122/278 (43%), Gaps = 22/278 (7%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72
+ +LA M LL+ + G +N LT++ + +LRTP + ++L+LA+AD + L +
Sbjct: 36 QFSMLAAYMFLLI--VLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTS 93
Query: 73 AT-SSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC---TRSQLAWNSA 128
+SL + +G GC GF + ++ S +A RY C + + N A
Sbjct: 94 TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHA 153
Query: 129 VSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFA 186
+ V F W+ + AA PL GW Y E L C +DY K + N SF+ M +F
Sbjct: 154 IMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFT 213
Query: 187 MPLFI----------TITSYSLMEQKLGKSGHLQVNTT----LPARTLLLGWGPYAILYL 232
+P+ I T+ + +Q+ + + T + L+ W PYA +
Sbjct: 214 IPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAF 273
Query: 233 YAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNE 270
Y ++ P +PA AK N + Y + N+
Sbjct: 274 YIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNK 311
>gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo
sapiens]
Length = 364
Score = 68.2 bits (165), Expect = 8e-12
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 28/275 (10%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V ++ + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVV--IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISV 111
Query: 78 LRR----WPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 132
+ + + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIV 171
Query: 133 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 188
F W+ +A W A P+ GW Y L T C D G S++ + P
Sbjct: 172 GIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITP 231
Query: 189 LFITITSYSLM---------EQKLGKSGH-LQVNTTLPARTLLLG----WGPYAILYLYA 234
L I + Y + +QK +S + T ++L WGPYA +A
Sbjct: 232 LSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFA 291
Query: 235 VIADVTSISPKLQMVPALIAKMVPTINAINYALGN 269
P + +PA AK N + Y N
Sbjct: 292 AANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMN 326
>gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo
sapiens]
Length = 364
Score = 68.2 bits (165), Expect = 8e-12
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 28/275 (10%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V ++ + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVV--IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISV 111
Query: 78 LRR----WPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 132
+ + + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIV 171
Query: 133 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 188
F W+ +A W A P+ GW Y L T C D G S++ + P
Sbjct: 172 GIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITP 231
Query: 189 LFITITSYSLM---------EQKLGKSGH-LQVNTTLPARTLLLG----WGPYAILYLYA 234
L I + Y + +QK +S + T ++L WGPYA +A
Sbjct: 232 LSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFA 291
Query: 235 VIADVTSISPKLQMVPALIAKMVPTINAINYALGN 269
P + +PA AK N + Y N
Sbjct: 292 AANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMN 326
>gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo
sapiens]
Length = 364
Score = 67.0 bits (162), Expect = 2e-11
Identities = 66/277 (23%), Positives = 113/277 (40%), Gaps = 32/277 (11%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V A + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVVTA--SVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISI 111
Query: 78 LRR----WPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 132
+ + + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIV 171
Query: 133 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 188
F W+ SA W A P+ GW Y L T C D G S++ + +P
Sbjct: 172 GIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIP 231
Query: 189 LFITITSY----------------SLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYL 232
L I + Y S QK K V + A + WGPY
Sbjct: 232 LAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVC--WGPYTFFAC 289
Query: 233 YAVIADVTSISPKLQMVPALIAKMVPTINAINYALGN 269
+A + P + +PA AK N + Y N
Sbjct: 290 FAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMN 326
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 60.5 bits (145), Expect = 2e-09
Identities = 52/184 (28%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
A+ VL+ + + N L I S + +LR ++ V+SLA+AD +++ S+
Sbjct: 29 ALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSI 88
Query: 78 LRR-WPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC--TRSQLAWNSAVSL--V 132
W G CQ GF ++ + SI + IA RY + C + ++S SL V
Sbjct: 89 FNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYV 148
Query: 133 LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFIT 192
L +WL + A LP L G Y+P CT S +++ + F+F +P+ I
Sbjct: 149 LLIWLLT-LAAVLPNLRAGTLQYDPRIYSCTFAQSVS----SAYTIAVVVFHFLVPMIIV 203
Query: 193 ITSY 196
I Y
Sbjct: 204 IFCY 207
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 60.1 bits (144), Expect = 2e-09
Identities = 74/315 (23%), Positives = 128/315 (40%), Gaps = 47/315 (14%)
Query: 1 MAETSALPTGFGELE------------VLAVGMVLLVEALSGLSLNTLTIFSFCKTPELR 48
M T A+PT +G + ++ + +++ + L N++ I + K +LR
Sbjct: 1 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR 60
Query: 49 TPCHLLVLSLALADSGISLNALVAATSSL-LRRWPYGSDGCQAHGFQGFVTALASICSSA 107
++ V+SL++AD +++ ++ + W CQ GF ++ + SI +
Sbjct: 61 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV 120
Query: 108 AIAWGRYHHYCTRSQL-----AWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCC 162
AIA RY + C Q N+ + LV+ W+ + A LP + G +Y+P C
Sbjct: 121 AIAINRYCYICHSLQYERIFSVRNTCIYLVI-TWIMTVL-AVLPNMYIGTIEYDPRTYTC 178
Query: 163 TLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKL----GKSGHLQVNTTLPAR 218
+Y N F T+ +F +PL I Y + K+ +G N R
Sbjct: 179 IFNY----LNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVR 234
Query: 219 TLLLGWGPYAILYLYA-------VIADVTSISPK---------LQMVPALIAKMVPTINA 262
L + I L+A V+ + ++SPK L + IA +NA
Sbjct: 235 NFLT---MFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNA 291
Query: 263 INYALGNEMVCRGIW 277
+ Y L NE R W
Sbjct: 292 VIYGLLNENFRREYW 306
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +++ +
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 71 --VAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTRSQ 122
V+ T + +W +G C + ASI + I+ RY Y R
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 123 LAWNSAVSLVLFVWLSSAFWAALPLLGW 150
++L VWL SA PL GW
Sbjct: 196 --GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +++ +
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 71 --VAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTRSQ 122
V+ T + +W +G C + ASI + I+ RY Y R
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 123 LAWNSAVSLVLFVWLSSAFWAALPLLGW 150
++L VWL SA PL GW
Sbjct: 196 --GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +++ +
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 71 --VAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTRSQ 122
V+ T + +W +G C + ASI + I+ RY Y R
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 123 LAWNSAVSLVLFVWLSSAFWAALPLLGW 150
++L VWL SA PL GW
Sbjct: 196 --GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
Length = 398
Score = 57.0 bits (136), Expect = 2e-08
Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 23/205 (11%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72
E +V+ + +VL++ L G+ N + + +T +RTP + ++SLA+AD L LVA
Sbjct: 23 EYQVVTILLVLIICGL-GIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVAD----LMVLVA 77
Query: 73 A-----TSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC----TRSQL 123
A T S+ W YG GC + ++ AS CS A RY C +
Sbjct: 78 AGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLC 137
Query: 124 AWNSAVSLVLFVW----LSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFT 179
++ A +++FVW L W L L Y + +C K RN+ S ++
Sbjct: 138 TFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISC----GYKISRNYYSPIYL 193
Query: 180 MSFFNF-AMPLFITITSYSLMEQKL 203
M F F +P+ + Y + + L
Sbjct: 194 MDFGVFYVVPMILATVLYGFIARIL 218
>gi|71999146 opsin 5 isoform 2 [Homo sapiens]
Length = 189
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 20/141 (14%)
Query: 145 LPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLFITITSY------ 196
+PL+G G Y EP GT CTLD+ ++ F+ + FF +P + + SY
Sbjct: 1 MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK 60
Query: 197 --------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAILYLYAVIADVTSISP 244
+ + ++ S L++ T A + L+ W PYA++ +++ SI
Sbjct: 61 VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 120
Query: 245 KLQMVPALIAKMVPTINAINY 265
+L +VP L+AK N I Y
Sbjct: 121 QLSVVPTLLAKSAAMYNPIIY 141
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 55.5 bits (132), Expect = 6e-08
Identities = 49/196 (25%), Positives = 88/196 (44%), Gaps = 6/196 (3%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL-V 71
E+ V+ +G+V+ + L+ + N L I + K L+T + + SLA AD + L +
Sbjct: 30 EVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF 89
Query: 72 AATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCT----RSQLAWNS 127
A L++ W +G+ C+ + ASI + IA RY + +S L N
Sbjct: 90 GAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNK 149
Query: 128 AVSLVLFVWLSSAFWAALPL-LGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFA 186
A ++L VW+ S + LP+ + W ++ C + ++ S +F
Sbjct: 150 ARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFY 209
Query: 187 MPLFITITSYSLMEQK 202
+PL I + YS + Q+
Sbjct: 210 VPLVIMVFVYSRVFQE 225
>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
sapiens]
Length = 348
Score = 55.1 bits (131), Expect = 7e-08
Identities = 62/280 (22%), Positives = 116/280 (41%), Gaps = 30/280 (10%)
Query: 14 LEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAA 73
L+ +G V L+ G LN + + + + +LR P + ++++++ + + ++
Sbjct: 36 LQAAFMGTVFLI----GFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPV 91
Query: 74 -TSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCT---RSQLAWNSAV 129
+S + +G C GF G V L + S A +A+ RY C + + A+
Sbjct: 92 FVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHAL 151
Query: 130 SLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLD-YSKGDR----NFTSFLFTMSFFN 184
++VL W + P GW + E L C D Y+ G + ++T FLF F
Sbjct: 152 TVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLF---IFC 208
Query: 185 FAMPLFITITSYSLMEQKLGKSGHLQVNTTLPART---------LLLG-----WGPYAIL 230
F +PL + SY+ + + L Q + + +++G + PYA
Sbjct: 209 FIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAF 268
Query: 231 YLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNE 270
+Y V + +L +P+ +K N I Y N+
Sbjct: 269 AMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNK 308
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 54.3 bits (129), Expect = 1e-07
Identities = 46/149 (30%), Positives = 69/149 (46%), Gaps = 5/149 (3%)
Query: 5 SALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSG 64
S P + +G+++ + L ++ N L I + KTP L+T +L ++SLA AD
Sbjct: 47 SESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLV 106
Query: 65 ISLNAL-VAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCT 119
+ L + AT + RW YGS C+ + ASI + IA RY +
Sbjct: 107 MGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRY 166
Query: 120 RSQLAWNSAVSLVLFVWLSSAFWAALPLL 148
+S L A LV VW SA + LP+L
Sbjct: 167 QSLLTRARARGLVCTVWAISALVSFLPIL 195
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/154 (30%), Positives = 72/154 (46%), Gaps = 11/154 (7%)
Query: 2 AETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALA 61
A TS LP E G +L + L+ + N L I + TP L+T ++ V SLA A
Sbjct: 25 ANTSGLPGV--PWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAA 82
Query: 62 DSGISLNAL-VAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR 120
D + L + AAT +L WP G+ GC+ + ASI + A+A RY
Sbjct: 83 DLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRY--LAVT 140
Query: 121 SQLAWNSAV------SLVLFVWLSSAFWAALPLL 148
+ L + + V + V+ VW+ SA + P++
Sbjct: 141 NPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIM 174
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/185 (24%), Positives = 81/185 (43%), Gaps = 12/185 (6%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL-VAATSS 76
A+ VL+V + N L I S + +LR +L ++SLALAD ++ + +
Sbjct: 42 ALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAI 101
Query: 77 LLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC-----TRSQLAWNSAVSL 131
W G + C+A F ++ + S+ + AIA RY + C R W++ + +
Sbjct: 102 FYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHI 161
Query: 132 VLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFI 191
L +WL + A LP G +Y+P CT + T + + +F +P+ +
Sbjct: 162 CL-IWLLTVV-ALLPNFFVGSLEYDPRIYSCTFIQTAS----TQYTAAVVVIHFLLPIAV 215
Query: 192 TITSY 196
Y
Sbjct: 216 VSFCY 220
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/246 (23%), Positives = 102/246 (41%), Gaps = 20/246 (8%)
Query: 12 GELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALV 71
G+ + + + V L GL N++ I+ + +++T ++ +L+LA+AD + L+
Sbjct: 54 GQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPF 113
Query: 72 AATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY---HHYCTRSQLAWNSA 128
TS+LLR WP+G+ C+ V SI ++ RY H ++ +
Sbjct: 114 LVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTV 173
Query: 129 VSLV-LFVWLSSAFWAALPLLGWGHYDYEPLGT--CCTLDYSKGDRNFTSFLFTMSFFNF 185
+V L VW+ S LP++ + GT C L R F+ F
Sbjct: 174 AKVVNLGVWVLSLL-VILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGF 232
Query: 186 AMPLFITITSYSLMEQKLG----KSGHLQVNTTLPARTLL---------LGWGPYAILYL 232
+P+ Y L+ K+ K+G Q + TL+ + W P+ ++ L
Sbjct: 233 LLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQL 292
Query: 233 YAVIAD 238
V A+
Sbjct: 293 VNVFAE 298
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 52.8 bits (125), Expect = 4e-07
Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 8/186 (4%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNALVAATS 75
LA G+V+ V L N + I+ +RT + +++LA +D+ ++ N LV
Sbjct: 90 LAYGVVVAVAVLG----NLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIY 145
Query: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC--TRSQLAWNSAVSLVL 133
+L W +G++ C+ F ASI S AIA RY + +L+ + ++
Sbjct: 146 ALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIG 205
Query: 134 FVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITI 193
+W+ AF A P + P T C + + +G + ++ + + PL I
Sbjct: 206 SIWI-LAFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMG 264
Query: 194 TSYSLM 199
+Y+++
Sbjct: 265 ITYTIV 270
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 52.4 bits (124), Expect = 5e-07
Identities = 42/139 (30%), Positives = 63/139 (45%), Gaps = 5/139 (3%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL-VAATS 75
++VG+VL L + N L I S LRTP + +++LA+AD +S L +A
Sbjct: 46 ISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAAL 105
Query: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQLAWNSAVSL 131
+L W G C + ASI S AI+ RY + + + A+
Sbjct: 106 EVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILA 165
Query: 132 VLFVWLSSAFWAALPLLGW 150
+L VW+ S + PLLGW
Sbjct: 166 LLSVWVLSTVISIGPLLGW 184
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 52.4 bits (124), Expect = 5e-07
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 7 LPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS 66
LP G L+V VG+ L V + GL N L ++ + +++T ++ + +LALAD+ +
Sbjct: 46 LPLG---LKVTIVGLYLAV-CVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVL 101
Query: 67 LNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC----TRSQ 122
L T LL WP+G+ C+ + S + A++ RY C
Sbjct: 102 LTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDV 161
Query: 123 LAWNSAVSLVLFVW-LSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMS 181
+ A ++ + +W L+S + ++G + E + C + D F +
Sbjct: 162 RTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEI-ECLVEIPTPQDYWGPVFAICIF 220
Query: 182 FFNFAMPLFITITSYSLMEQKL 203
F+F +P+ + YSLM ++L
Sbjct: 221 LFSFIVPVLVISVCYSLMIRRL 242
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 52.4 bits (124), Expect = 5e-07
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 10/202 (4%)
Query: 7 LPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS 66
LP G L+V VG+ L V + GL N L ++ + +++T ++ + +LALAD+ +
Sbjct: 46 LPLG---LKVTIVGLYLAV-CVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVL 101
Query: 67 LNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC----TRSQ 122
L T LL WP+G+ C+ + S + A++ RY C
Sbjct: 102 LTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDV 161
Query: 123 LAWNSAVSLVLFVW-LSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMS 181
+ A ++ + +W L+S + ++G + E + C + D F +
Sbjct: 162 RTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEI-ECLVEIPTPQDYWGPVFAICIF 220
Query: 182 FFNFAMPLFITITSYSLMEQKL 203
F+F +P+ + YSLM ++L
Sbjct: 221 LFSFIVPVLVISVCYSLMIRRL 242
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 49.7 bits (117), Expect = 3e-06
Identities = 45/185 (24%), Positives = 77/185 (41%), Gaps = 12/185 (6%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL-VAATS 75
+ VG+ L L ++ N L I S L+T + +++LA+AD +S L +AT
Sbjct: 97 VGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATM 156
Query: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQLAWNSAVSL 131
+L W +G C + ASI S I+ RY H + + A ++
Sbjct: 157 EVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAI 216
Query: 132 VLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFI 191
+ +W+ + + PLLGW P C + G F+S +F +P+ +
Sbjct: 217 LALLWVVALVVSVGPLLGWKE-PVPPDERFCGITEEAGYAVFSSVC------SFYLPMAV 269
Query: 192 TITSY 196
+ Y
Sbjct: 270 IVVMY 274
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,309,451
Number of Sequences: 37866
Number of extensions: 403587
Number of successful extensions: 1555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 1339
Number of HSP's gapped (non-prelim): 302
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.