Guide to the Human Genome
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Search of human proteins with 60279268

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2
isoform b [Homo sapiens]
         (471 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo...   952   0.0  
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor...   946   0.0  
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]       91   3e-18
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]      88   1e-17
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]     81   2e-15
gi|28467003 kinase interacting stathmin [Homo sapiens]                 79   9e-15
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]     74   3e-13
gi|7661952 squamous cell carcinoma antigen recognized by T cells...    74   4e-13
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...    72   1e-12
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...    70   4e-12
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...    70   4e-12
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]        65   1e-10
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]               63   5e-10
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]               63   5e-10
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]     63   7e-10
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ...    61   2e-09
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                      61   3e-09
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                      61   3e-09
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                      61   3e-09
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                      61   3e-09
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                      61   3e-09
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...    61   3e-09
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    60   4e-09
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    60   4e-09
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    60   4e-09
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     58   2e-08
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         57   4e-08
gi|41393554 LUC7-like isoform b [Homo sapiens]                         56   8e-08
gi|8922297 LUC7-like isoform a [Homo sapiens]                          56   8e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            55   1e-07

>gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform
           b [Homo sapiens]
          Length = 471

 Score =  952 bits (2461), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR 60
           MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
Sbjct: 1   MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR 60

Query: 61  RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA 120
           RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
Sbjct: 61  RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA 120

Query: 121 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ 180
           LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
Sbjct: 121 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ 180

Query: 181 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE 240
           APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
Sbjct: 181 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE 240

Query: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300
           NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
Sbjct: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300

Query: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLM 360
           GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLM
Sbjct: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLM 360

Query: 361 SSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV 420
           SSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV
Sbjct: 361 SSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV 420

Query: 421 EVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW 471
           EVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
Sbjct: 421 EVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW 471


>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
           [Homo sapiens]
          Length = 475

 Score =  946 bits (2446), Expect = 0.0
 Identities = 471/475 (99%), Positives = 471/475 (99%), Gaps = 4/475 (0%)

Query: 1   MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR 60
           MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
Sbjct: 1   MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR 60

Query: 61  RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA 120
           RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
Sbjct: 61  RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA 120

Query: 121 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ 180
           LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
Sbjct: 121 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ 180

Query: 181 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE 240
           APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
Sbjct: 181 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE 240

Query: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300
           NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
Sbjct: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300

Query: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATL----STINQTPVTLQV 356
           GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATL    STINQTPVTLQV
Sbjct: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQV 360

Query: 357 PGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP 416
           PGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP
Sbjct: 361 PGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP 420

Query: 417 VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW 471
           VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
Sbjct: 421 VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW 475


>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
          Length = 524

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 108/516 (20%), Positives = 196/516 (37%), Gaps = 98/516 (18%)

Query: 12  NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68
           +E + ++ K+++ R RSH R RS+ ++R+ RSRDR  +  +S  R R R   R +  +R 
Sbjct: 28  HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86

Query: 69  AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126
                 G  RSP    K    +R    +P          + K+     + P    +  +T
Sbjct: 87  RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146

Query: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186
           P+                 R AR ++   +   I    + +FF+   ++  +        
Sbjct: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188

Query: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245
                 + K  A++EF  V     A+   G    G  + ++    +      M+ N    
Sbjct: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245

Query: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
             G +         +L++G L   + +D ++ +   FG +++  L+ DS TG SKGY F 
Sbjct: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296

Query: 306 EYVDINVTDQAIAGLNGMQLGDKKLLV----QRASVGAKNATLST--INQTPVT------ 353
            + D     +A+  LNG +L  + + V    +R    + ++ L +  + +T +       
Sbjct: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356

Query: 354 ------------LQVPGLMSSQVQMGGH-------------------------------P 370
                       LQ+P      +QM G                                 
Sbjct: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLA 416

Query: 371 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV 430
           T+   L NM  P+   +     EI +DV +EC+K+G V  I + +          G ++V
Sbjct: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 470

Query: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 466
           +  S+     A+  L GR FA +++   Y    +YH
Sbjct: 471 KCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 506


>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
          Length = 530

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 108/522 (20%), Positives = 196/522 (37%), Gaps = 104/522 (19%)

Query: 12  NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68
           +E + ++ K+++ R RSH R RS+ ++R+ RSRDR  +  +S  R R R   R +  +R 
Sbjct: 28  HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86

Query: 69  AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126
                 G  RSP    K    +R    +P          + K+     + P    +  +T
Sbjct: 87  RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146

Query: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186
           P+                 R AR ++   +   I    + +FF+   ++  +        
Sbjct: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188

Query: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245
                 + K  A++EF  V     A+   G    G  + ++    +      M+ N    
Sbjct: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245

Query: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
             G +         +L++G L   + +D ++ +   FG +++  L+ DS TG SKGY F 
Sbjct: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296

Query: 306 EYVDINVTDQAIAGLNGMQLGDKKLLV----QRASVGAKNATLST--INQTPVT------ 353
            + D     +A+  LNG +L  + + V    +R    + ++ L +  + +T +       
Sbjct: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356

Query: 354 ------------LQVPGLMSSQVQMGGH-------------------------------- 369
                       LQ+P      +QM G                                 
Sbjct: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAA 416

Query: 370 -----PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG 424
                 T+   L NM  P+   +     EI +DV +EC+K+G V  I + +         
Sbjct: 417 SVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SA 470

Query: 425 CGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 466
            G ++V+  S+     A+  L GR FA +++   Y    +YH
Sbjct: 471 QGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 512


>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
          Length = 439

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 86/321 (26%), Positives = 136/321 (42%), Gaps = 50/321 (15%)

Query: 21  ENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRS 79
           E   +KRS S ++SRDRKR SRSRDR R R + S SR   R+ +  +R     HG   RS
Sbjct: 57  ETSKKKRSRSHNKSRDRKR-SRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRS 115

Query: 80  PRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPV 139
             H ++ +V  ++  PP      T  +Y   ++              P     +P   PV
Sbjct: 116 RDHRREDRV--HYRSPPLA----TGYRYGHSKS--------------PHFREKSPVREPV 155

Query: 140 VG-SQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN-- 196
              S   R AR ++   +   I    + DFF+A  +           V  V+I  D+N  
Sbjct: 156 DNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSR 204

Query: 197 ----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVS 251
                A++EF  +     A+   G    G  + ++    +   L  M+ N      G + 
Sbjct: 205 RSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM- 263

Query: 252 TVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDIN 311
                   +L++G L   + +D ++ +   FG +    L+KDS TG SKGY F  + D  
Sbjct: 264 --------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 315

Query: 312 VTDQAIAGLNGMQLGDKKLLV 332
              +A+  LNG +L  + + V
Sbjct: 316 CARRALEQLNGFELAGRPMRV 336


>gi|28467003 kinase interacting stathmin [Homo sapiens]
          Length = 419

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 41/98 (41%), Positives = 63/98 (64%), Gaps = 5/98 (5%)

Query: 370 PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIF 429
           PT VL L+N++  + L ++EEYE++VEDV++EC KYG V S+ +P+     E PG G++F
Sbjct: 319 PTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPK-----ENPGRGQVF 373

Query: 430 VEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHR 467
           VE+ +  D + A + LTGR F  + VV  +    +Y R
Sbjct: 374 VEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKR 411


>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
          Length = 423

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 81/332 (24%), Positives = 130/332 (39%), Gaps = 83/332 (25%)

Query: 14  NKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR------RSKPLTR 67
           + + RD++   R+ S SRS  R  + RSRS DRR+  + S SRD RR      RS PL  
Sbjct: 59  SNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSE-SRSRDHRREDRVHYRSPPLAT 117

Query: 68  GAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTP 127
           G +  H    +SP   +K  VR+  D                               ++P
Sbjct: 118 GYRYGHS---KSPHFREKSPVREPVD------------------------------NLSP 144

Query: 128 DGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVL 187
           +                 R AR ++   +   I    + DFF+A  +           V 
Sbjct: 145 E----------------ERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VR 177

Query: 188 AVQINQDKN------FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSE 240
            V+I  D+N       A++EF  +     A+   G    G  + ++    +   L  M+ 
Sbjct: 178 DVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMAN 237

Query: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300
           N      G +         +L++G L   + +D ++ +   FG +    L+KDS TG SK
Sbjct: 238 NLQKGNGGPM---------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288

Query: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
           GY F  + D     +A+  LNG +L  + + V
Sbjct: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRV 320


>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
           [Homo sapiens]
          Length = 963

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 81/354 (22%), Positives = 146/354 (41%), Gaps = 31/354 (8%)

Query: 10  QLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGA 69
           Q  E +  R  E R +      +  +  + ++  R +R R ++ A + +++   P  RGA
Sbjct: 567 QKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQR-KRARAEKKALKKKKKIRGPEKRGA 625

Query: 70  KEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLP-TMTPD 128
            E+          E+  K R+  +  P   E  T     A   AG+  A  + P +   +
Sbjct: 626 DEDDEKEWGDDEEEQPSKRRRVENSIPAAGE--TQNVEVAAGPAGKCAAVDVEPPSKQKE 683

Query: 129 GLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLA 188
             A     +P V    ++ +  ++V N+P+ + E           +L  L +A G  V  
Sbjct: 684 KAASLKRDMPKVLHDSSKDSITVFVSNLPYSMQEP--------DTKLRPLFEACGEVVQI 735

Query: 189 VQINQDKN----FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSV 244
             I  ++     + ++EF+      QA+  D    +G      RP    P    S+NP  
Sbjct: 736 RPIFSNRGDFRGYCYVEFKEEKSALQALEMDRKSVEG------RPMFVSPCVDKSKNPDF 789

Query: 245 YVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAF 304
            V    +++     HKLFI GLP     ++++E+  + G +K   LV + A G  KG A+
Sbjct: 790 KVFRYSTSL---EKHKLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRA-GKPKGLAY 845

Query: 305 CEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
            EY + +   QA+  ++GM + +  +      V   N     + + P T + PG
Sbjct: 846 VEYENESQASQAVMKMDGMTIKENII-----KVAISNPPQRKVPEKPETRKAPG 894


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 58/255 (22%), Positives = 114/255 (44%), Gaps = 41/255 (16%)

Query: 98  GFEHITPMQYKAMQAAGQ------IPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRL 151
           G   +TP Q +A+Q A +      I +  +  T+      +T   +     +      R+
Sbjct: 55  GLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRV 114

Query: 152 YVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD------KNFAFLEFRSV 205
           YVG+I + + E+ +   F           AP  P+ ++ ++ D      K FAF+E+   
Sbjct: 115 YVGSIYYELGEDTIRQAF-----------APFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 163

Query: 206 DETTQAMA-FDGIIFQGQSLKIRRPHDY---QPL-PGMSENPSVYVPGVVSTVVPDSAHK 260
           +    A+   + ++  G+++K+ RP +    QP+   ++E    +             ++
Sbjct: 164 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAF-------------NR 210

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           +++  +   L+DD +K +  +FG +K+  L +D  TG  KGY F EY     +  A++ +
Sbjct: 211 IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSM 270

Query: 321 NGMQLGDKKLLVQRA 335
           N   LG + L V +A
Sbjct: 271 NLFDLGGQYLRVGKA 285



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 373 VLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG--CGKIFV 430
           V+ L NMV P+++ DD E E     V +EC K+G V  + I +   G E       KIFV
Sbjct: 446 VMVLRNMVDPKDIDDDLEGE-----VTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 500

Query: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRD 469
           EF+   +  KA+Q L GR FA R VV +  D + +   D
Sbjct: 501 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSD 539



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/77 (29%), Positives = 42/77 (54%)

Query: 260 KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAG 319
           ++++G +   L +D +++    FGP+K+ ++  DS T   KG+AF EY        A+  
Sbjct: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 172

Query: 320 LNGMQLGDKKLLVQRAS 336
           +N + LG + + V R S
Sbjct: 173 MNSVMLGGRNIKVGRPS 189


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 48/197 (24%), Positives = 94/197 (47%), Gaps = 35/197 (17%)

Query: 150 RLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD------KNFAFLEFR 203
           R+YVG+I + + E+ +   F           AP  P+ ++ ++ D      K FAF+E+ 
Sbjct: 87  RVYVGSIYYELGEDTIRQAF-----------APFGPIKSIDMSWDSVTMKHKGFAFVEYE 135

Query: 204 SVDETTQAMA-FDGIIFQGQSLKIRRPHDY---QPL-PGMSENPSVYVPGVVSTVVPDSA 258
             +    A+   + ++  G+++K+ RP +    QP+   ++E    +             
Sbjct: 136 VPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAF------------- 182

Query: 259 HKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIA 318
           +++++  +   L+DD +K +  +FG +K+  L +D  TG  KGY F EY     +  A++
Sbjct: 183 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVS 242

Query: 319 GLNGMQLGDKKLLVQRA 335
            +N   LG + L V +A
Sbjct: 243 SMNLFDLGGQYLRVGKA 259



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 373 VLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG--CGKIFV 430
           V+ L NMV P+++ DD E E     V +EC K+G V  + I +   G E       KIFV
Sbjct: 420 VMVLRNMVDPKDIDDDLEGE-----VTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 474

Query: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRD 469
           EF+   +  KA+Q L GR FA R VV +  D + +   D
Sbjct: 475 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSD 513



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/77 (29%), Positives = 42/77 (54%)

Query: 260 KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAG 319
           ++++G +   L +D +++    FGP+K+ ++  DS T   KG+AF EY        A+  
Sbjct: 87  RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 146

Query: 320 LNGMQLGDKKLLVQRAS 336
           +N + LG + + V R S
Sbjct: 147 MNSVMLGGRNIKVGRPS 163


>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 48/197 (24%), Positives = 94/197 (47%), Gaps = 35/197 (17%)

Query: 150 RLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD------KNFAFLEFR 203
           R+YVG+I + + E+ +   F           AP  P+ ++ ++ D      K FAF+E+ 
Sbjct: 130 RVYVGSIYYELGEDTIRQAF-----------APFGPIKSIDMSWDSVTMKHKGFAFVEYE 178

Query: 204 SVDETTQAMA-FDGIIFQGQSLKIRRPHDY---QPL-PGMSENPSVYVPGVVSTVVPDSA 258
             +    A+   + ++  G+++K+ RP +    QP+   ++E    +             
Sbjct: 179 VPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAF------------- 225

Query: 259 HKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIA 318
           +++++  +   L+DD +K +  +FG +K+  L +D  TG  KGY F EY     +  A++
Sbjct: 226 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVS 285

Query: 319 GLNGMQLGDKKLLVQRA 335
            +N   LG + L V +A
Sbjct: 286 SMNLFDLGGQYLRVGKA 302



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 373 VLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPG--CGKIFV 430
           V+ L NMV P+++ DD E E     V +EC K+G V  + I +   G E       KIFV
Sbjct: 463 VMVLRNMVDPKDIDDDLEGE-----VTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 517

Query: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRD 469
           EF+   +  KA+Q L GR FA R VV +  D + +   D
Sbjct: 518 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSD 556



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/77 (29%), Positives = 42/77 (54%)

Query: 260 KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAG 319
           ++++G +   L +D +++    FGP+K+ ++  DS T   KG+AF EY        A+  
Sbjct: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 189

Query: 320 LNGMQLGDKKLLVQRAS 336
           +N + LG + + V R S
Sbjct: 190 MNSVMLGGRNIKVGRPS 206


>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
          Length = 577

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 32/104 (30%), Positives = 51/104 (49%)

Query: 254 VPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVT 313
           V  S   +F+G +P    ++Q+K++ +  GP+ +F LV D  TG  KGY FCEY D    
Sbjct: 11  VDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETA 70

Query: 314 DQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVP 357
             A+  LNG +   + L V  A+       L ++      ++ P
Sbjct: 71  LSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESP 114



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 18/88 (20%)

Query: 146 RQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD------KNFAF 199
           R  R ++VGNIP+  TEE + D F+              PV++ ++  D      K + F
Sbjct: 13  RSLRSVFVGNIPYEATEEQLKDIFSEV-----------GPVVSFRLVYDRETGKPKGYGF 61

Query: 200 LEFRSVDETTQAMA-FDGIIFQGQSLKI 226
            E++  +    AM   +G  F G++L++
Sbjct: 62  CEYQDQETALSAMRNLNGREFSGRALRV 89


>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
          Length = 367

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 56/194 (28%), Positives = 84/194 (43%), Gaps = 39/194 (20%)

Query: 256 DSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQ 315
           DS   L +  LP  +  D+ K L  S G +++  LV+D  TG S GY F  Y D N  D+
Sbjct: 36  DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 95

Query: 316 AIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLC 375
           AI  LNG++L  K + V  A     +A++   N     L V GL  +  Q          
Sbjct: 96  AINTLNGLKLQTKTIKVSYAR--PSSASIRDAN-----LYVSGLPKTMSQ---------- 138

Query: 376 LMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSV 435
                        +E E++        S+YG + +  I   VD V     G  F+ F   
Sbjct: 139 -------------KEMEQLF-------SQYGRIITSRIL--VDQVTGVSRGVGFIRFDKR 176

Query: 436 FDCQKAMQGLTGRK 449
            + ++A++GL G+K
Sbjct: 177 IEAEEAIKGLNGQK 190



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  ++  ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 112 VSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFI 171

Query: 306 EYVDINVTDQAIAGLNGMQ 324
            +      ++AI GLNG +
Sbjct: 172 RFDKRIEAEEAIKGLNGQK 190



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 20/72 (27%), Positives = 36/72 (50%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           +F+  L    ++  + +L   FG +    +++D  T   KG+ F    + +    AIA L
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345

Query: 321 NGMQLGDKKLLV 332
           NG +LG++ L V
Sbjct: 346 NGYRLGERVLQV 357


>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
          Length = 360

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 56/194 (28%), Positives = 84/194 (43%), Gaps = 39/194 (20%)

Query: 256 DSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQ 315
           DS   L +  LP  +  D+ K L  S G +++  LV+D  TG S GY F  Y D N  D+
Sbjct: 36  DSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADK 95

Query: 316 AIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLC 375
           AI  LNG++L  K + V  A     +A++   N     L V GL  +  Q          
Sbjct: 96  AINTLNGLKLQTKTIKVSYAR--PSSASIRDAN-----LYVSGLPKTMSQ---------- 138

Query: 376 LMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSV 435
                        +E E++        S+YG + +  I   VD V     G  F+ F   
Sbjct: 139 -------------KEMEQLF-------SQYGRIITSRIL--VDQVTGVSRGVGFIRFDKR 176

Query: 436 FDCQKAMQGLTGRK 449
            + ++A++GL G+K
Sbjct: 177 IEAEEAIKGLNGQK 190



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  ++  ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 112 VSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFI 171

Query: 306 EYVDINVTDQAIAGLNGMQ 324
            +      ++AI GLNG +
Sbjct: 172 RFDKRIEAEEAIKGLNGQK 190



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 20/72 (27%), Positives = 36/72 (50%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           +F+  L    ++  + +L   FG +    +++D  T   KG+ F    + +    AIA L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338

Query: 321 NGMQLGDKKLLV 332
           NG +LG++ L V
Sbjct: 339 NGYRLGERVLQV 350


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 75/310 (24%), Positives = 116/310 (37%), Gaps = 74/310 (23%)

Query: 30  SRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVR 89
           +RSR RDR RR  SR R      S  R  R RS+   R     HG   RS  H ++ +V 
Sbjct: 60  NRSRDRDRYRRRNSRSR------SPGRQCRHRSRSWDR----RHGSESRSRDHRREDRVH 109

Query: 90  KYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQAR 149
                            Y++   A   P   L P                      R AR
Sbjct: 110 -----------------YRSPPLATGEPVDNLSPE--------------------ERDAR 132

Query: 150 RLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKN------FAFLEFR 203
            ++   +   I    + DFF+A  +           V  V+I  D+N       A++EF 
Sbjct: 133 TVFCMQLAARIRPRDLEDFFSAVGK-----------VRDVRIISDRNSRRSKGIAYVEFC 181

Query: 204 SVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVYVPGVVSTVVPDSAHKLF 262
            +     A+   G    G  + ++    +   L  M+ N      G +         +L+
Sbjct: 182 EIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM---------RLY 232

Query: 263 IGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNG 322
           +G L   + +D ++ +   FG +    L+KDS TG SKGY F  + D     +A+  LNG
Sbjct: 233 VGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNG 292

Query: 323 MQLGDKKLLV 332
            +L  + + V
Sbjct: 293 FELAGRPMRV 302



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/61 (42%), Positives = 34/61 (55%), Gaps = 7/61 (11%)

Query: 14  NKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR------RSKPLTR 67
           + + RD++   R+ S SRS  R  + RSRS DRR+  + S SRD RR      RS PL  
Sbjct: 59  SNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSE-SRSRDHRREDRVHYRSPPLAT 117

Query: 68  G 68
           G
Sbjct: 118 G 118


>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
           64kDa, tau variant [Homo sapiens]
          Length = 616

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 30/101 (29%), Positives = 48/101 (47%)

Query: 257 SAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQA 316
           S   +F+G +P    ++Q+K++ +  G + +F LV D  TG  KGY FCEY D      A
Sbjct: 14  SLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSA 73

Query: 317 IAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVP 357
           +  LNG +   + L V  A+       L ++      +  P
Sbjct: 74  MRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSP 114



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 144 MTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFR 203
           M R  R ++VGNIP+  TEE + D F+    +G +       V   +  + K + F E++
Sbjct: 11  MDRSLRSVFVGNIPYEATEEQLKDIFS---EVGSVVSF--RLVYDRETGKPKGYGFCEYQ 65

Query: 204 SVDETTQAMA-FDGIIFQGQSLKI 226
             +    AM   +G  F G++L++
Sbjct: 66  DQETALSAMRNLNGREFSGRALRV 89


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 39/211 (18%)

Query: 239 SENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGL 298
           S N +   P        DS   L +  LP  +  ++ + L  S G +++  LV+D  TG 
Sbjct: 26  SNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQ 85

Query: 299 SKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
           S GY F  Y+D    ++AI  LNG++L  K + V  A     +A++   N     L V G
Sbjct: 86  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSG 138

Query: 359 LMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVD 418
           L  +  Q                       +E E++        S+YG + +  I   VD
Sbjct: 139 LPKTMTQ-----------------------KELEQLF-------SQYGRIITSRI--LVD 166

Query: 419 GVEVPGCGKIFVEFTSVFDCQKAMQGLTGRK 449
            V     G  F+ F    + ++A++GL G+K
Sbjct: 167 QVTGVSRGVGFIRFDKRIEAEEAIKGLNGQK 197



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 119 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFI 178

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S  +  A LS + Q+P   + PG +
Sbjct: 179 RFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSP-NRRYPGPL 237

Query: 361 SSQVQ 365
             Q Q
Sbjct: 238 HHQAQ 242



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 235 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 294
           + GM+    + +PG   T        +F+  L    ++  + +L   FG +    +++D 
Sbjct: 278 IDGMTSLVGMNIPGHTGT-----GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 332

Query: 295 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 333 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 370



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+ R      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 60  EEFRSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 117

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 118 KVSYARPSSASIRD 131


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 39/211 (18%)

Query: 239 SENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGL 298
           S N +   P        DS   L +  LP  +  ++ + L  S G +++  LV+D  TG 
Sbjct: 29  SNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQ 88

Query: 299 SKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
           S GY F  Y+D    ++AI  LNG++L  K + V  A     +A++   N     L V G
Sbjct: 89  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSG 141

Query: 359 LMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVD 418
           L  +  Q                       +E E++        S+YG + +  I   VD
Sbjct: 142 LPKTMTQ-----------------------KELEQLF-------SQYGRIITSRI--LVD 169

Query: 419 GVEVPGCGKIFVEFTSVFDCQKAMQGLTGRK 449
            V     G  F+ F    + ++A++GL G+K
Sbjct: 170 QVTGVSRGVGFIRFDKRIEAEEAIKGLNGQK 200



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 122 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFI 181

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S  +  A LS + Q+P   + PG +
Sbjct: 182 RFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSP-NRRYPGPL 240

Query: 361 SSQVQ 365
             Q Q
Sbjct: 241 HHQAQ 245



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 235 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 294
           + GM+    + +PG   T        +F+  L    ++  + +L   FG +    +++D 
Sbjct: 267 IDGMTSLVGMNIPGHTGT-----GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 321

Query: 295 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 322 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 359



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+ R      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 63  EEFRSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 120

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 121 KVSYARPSSASIRD 134


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 39/211 (18%)

Query: 239 SENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGL 298
           S N +   P        DS   L +  LP  +  ++ + L  S G +++  LV+D  TG 
Sbjct: 26  SNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQ 85

Query: 299 SKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
           S GY F  Y+D    ++AI  LNG++L  K + V  A     +A++   N     L V G
Sbjct: 86  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSG 138

Query: 359 LMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVD 418
           L  +  Q                       +E E++        S+YG + +  I   VD
Sbjct: 139 LPKTMTQ-----------------------KELEQLF-------SQYGRIITSRI--LVD 166

Query: 419 GVEVPGCGKIFVEFTSVFDCQKAMQGLTGRK 449
            V     G  F+ F    + ++A++GL G+K
Sbjct: 167 QVTGVSRGVGFIRFDKRIEAEEAIKGLNGQK 197



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 119 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFI 178

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S  +  A LS + Q+P   + PG +
Sbjct: 179 RFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSP-NRRYPGPL 237

Query: 361 SSQVQ 365
             Q Q
Sbjct: 238 HHQAQ 242



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 235 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 294
           + GM+    + +PG   T        +F+  L    ++  + +L   FG +    +++D 
Sbjct: 264 IDGMTSLVGMNIPGHTGT-----GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 318

Query: 295 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 319 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 356



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+ R      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 60  EEFRSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 117

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 118 KVSYARPSSASIRD 131


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 39/211 (18%)

Query: 239 SENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGL 298
           S N +   P        DS   L +  LP  +  ++ + L  S G +++  LV+D  TG 
Sbjct: 43  SNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQ 102

Query: 299 SKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
           S GY F  Y+D    ++AI  LNG++L  K + V  A     +A++   N     L V G
Sbjct: 103 SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSG 155

Query: 359 LMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVD 418
           L  +  Q                       +E E++        S+YG + +  I   VD
Sbjct: 156 LPKTMTQ-----------------------KELEQLF-------SQYGRIITSRI--LVD 183

Query: 419 GVEVPGCGKIFVEFTSVFDCQKAMQGLTGRK 449
            V     G  F+ F    + ++A++GL G+K
Sbjct: 184 QVTGVSRGVGFIRFDKRIEAEEAIKGLNGQK 214



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 136 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFI 195

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S  +  A LS + Q+P   + PG +
Sbjct: 196 RFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSP-NRRYPGPL 254

Query: 361 SSQVQ 365
             Q Q
Sbjct: 255 HHQAQ 259



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 235 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 294
           + GM+    + +PG   T        +F+  L    ++  + +L   FG +    +++D 
Sbjct: 281 IDGMTSLVGMNIPGHTGT-----GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 335

Query: 295 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 336 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 373



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+ R      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 77  EEFRSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 134

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 135 KVSYARPSSASIRD 148


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 39/211 (18%)

Query: 239 SENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGL 298
           S N +   P        DS   L +  LP  +  ++ + L  S G +++  LV+D  TG 
Sbjct: 26  SNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQ 85

Query: 299 SKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPG 358
           S GY F  Y+D    ++AI  LNG++L  K + V  A     +A++   N     L V G
Sbjct: 86  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSG 138

Query: 359 LMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVD 418
           L  +  Q                       +E E++        S+YG + +  I   VD
Sbjct: 139 LPKTMTQ-----------------------KELEQLF-------SQYGRIITSRI--LVD 166

Query: 419 GVEVPGCGKIFVEFTSVFDCQKAMQGLTGRK 449
            V     G  F+ F    + ++A++GL G+K
Sbjct: 167 QVTGVSRGVGFIRFDKRIEAEEAIKGLNGQK 197



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 119 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFI 178

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S  +  A LS + Q+P   + PG +
Sbjct: 179 RFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSP-NRRYPGPL 237

Query: 361 SSQVQ 365
             Q Q
Sbjct: 238 HHQAQ 242



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 235 LPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDS 294
           + GM+    + +PG   T        +F+  L    ++  + +L   FG +    +++D 
Sbjct: 264 IDGMTSLVGMNIPGHTGT-----GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 318

Query: 295 ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 319 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 356



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+ R      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 60  EEFRSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 117

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 118 KVSYARPSSASIRD 131


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 53/194 (27%), Positives = 85/194 (43%), Gaps = 39/194 (20%)

Query: 256 DSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQ 315
           DS   L +  LP  +  +++K L  S G +++  LV+D  TG S GY F  Y+D    ++
Sbjct: 36  DSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEK 95

Query: 316 AIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLC 375
           AI  LNG++L  K + V  A     +A++   N     L V GL  +  Q          
Sbjct: 96  AINTLNGLRLQTKTIKVSYAR--PSSASIRDAN-----LYVSGLPKTMTQ---------- 138

Query: 376 LMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSV 435
                        +E E++        S+YG + +  I   VD V     G  F+ F   
Sbjct: 139 -------------KELEQLF-------SQYGRIITSRI--LVDQVTGISRGVGFIRFDKR 176

Query: 436 FDCQKAMQGLTGRK 449
            + ++A++GL G+K
Sbjct: 177 IEAEEAIKGLNGQK 190



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 10/125 (8%)

Query: 250 VSTVVPDSAH----KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
           VS   P SA      L++ GLP  +   ++++L + +G +    ++ D  TG+S+G  F 
Sbjct: 112 VSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFI 171

Query: 306 EYVDINVTDQAIAGLNGMQL--GDKKLLVQRA---SVGAKNATLSTINQTPVTLQVPGLM 360
            +      ++AI GLNG +     + + V+ A   S     A LS + Q+P   + PG +
Sbjct: 172 RFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSP-NRRYPGPL 230

Query: 361 SSQVQ 365
           + Q Q
Sbjct: 231 AQQAQ 235



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 17/179 (9%)

Query: 154 GNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMA 213
           G  P G TE   + F N   +         N  +  Q+ Q  N  +     + +  Q   
Sbjct: 188 GQKPPGATEPITVKFANNPSQ-------KTNQAILSQLYQSPNRRYPG--PLAQQAQRFR 238

Query: 214 FDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDD 273
            D ++     +K   P     + GM+    + +PG      P +   +F+  L    ++ 
Sbjct: 239 LDNLLNMAYGVKRFSP---MTIDGMTSLAGINIPGH-----PGTGWCIFVYNLAPDADES 290

Query: 274 QVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332
            + ++   FG +    +++D  T   KG+ F    + +    AIA LNG +LGD+ L V
Sbjct: 291 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 349



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 396 EDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVV 455
           E+++      G ++S ++ R  D +     G  FV +    D +KA+  L G +   + +
Sbjct: 53  EELKSLFGSIGEIESCKLVR--DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTI 110

Query: 456 VTKYCDPDSYHRRD 469
              Y  P S   RD
Sbjct: 111 KVSYARPSSASIRD 124


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 69/314 (21%), Positives = 134/314 (42%), Gaps = 74/314 (23%)

Query: 151 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDK------NFAFLEFRS 204
           LYVG++   +TE  + + F+           P  PVL++++ +D        +A++ F+ 
Sbjct: 13  LYVGDLHSDVTEAMLYEKFS-----------PAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61

Query: 205 VDETTQA---MAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKL 261
             +  +A   M FD  + +G+ ++I              +PS+   GV +         +
Sbjct: 62  PADAERALDTMNFD--VIKGKPIRIM---------WSQRDPSLRKSGVGN---------V 101

Query: 262 FIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLN 321
           FI  L   +++  + +  ++FG + +  +V D     SKGYAF  +      D+AI  +N
Sbjct: 102 FIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMN 159

Query: 322 GMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVL 381
           GM L D+K+ V R                            + ++G    E   +     
Sbjct: 160 GMLLNDRKVFVGR---------------------FKSRKEREAELGAKAKEFTNVYIKNF 198

Query: 382 PEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKA 441
            EE +DDE  +E+        S++G   S+++ R  +G +  G G  FV +    D  KA
Sbjct: 199 GEE-VDDESLKELF-------SQFGKTLSVKVMRDPNG-KSKGFG--FVSYEKHEDANKA 247

Query: 442 MQGLTGRKFANRVV 455
           ++ + G++ + +++
Sbjct: 248 VEEMNGKEISGKII 261



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 78/348 (22%), Positives = 143/348 (41%), Gaps = 65/348 (18%)

Query: 115 QIPATA--LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPF-----GITEEAMMD 167
           Q PA A   L TM  D   +   P+ ++ SQ     R+  VGN+        I  +A+ D
Sbjct: 60  QQPADAERALDTMNFD--VIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYD 117

Query: 168 FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEF-------RSVDETTQAMAFDGIIFQ 220
            F+A    G +        +    N  K +AF+ F       +++++    +  D  +F 
Sbjct: 118 TFSA---FGNILSCK----VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 221 GQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLT 280
           G+  K R+  + +      E  +VY+      V                 +D+ +KEL +
Sbjct: 171 GR-FKSRKEREAELGAKAKEFTNVYIKNFGEEV-----------------DDESLKELFS 212

Query: 281 SFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK 340
            FG   +  +++D   G SKG+ F  Y      ++A+  +NG ++  K + V RA    +
Sbjct: 213 QFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271

Query: 341 NATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRD 400
                   Q  +  +   L   Q ++  +    L + N+   ++ +DDE+       +R 
Sbjct: 272 -------RQAELKRKFEQL--KQERISRYQGVNLYIKNL---DDTIDDEK-------LRK 312

Query: 401 ECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGR 448
           E S +G + S ++   ++     G G  FV F+S  +  KA+  + GR
Sbjct: 313 EFSPFGSITSAKV--MLEDGRSKGFG--FVCFSSPEEATKAVTEMNGR 356



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           L+I  L + ++D+++++  + FG + +  ++ +   G SKG+ F  +       +A+  +
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 321 NGMQLGDKKLLVQRA 335
           NG  +G K L V  A
Sbjct: 354 NGRIVGSKPLYVALA 368


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 69/314 (21%), Positives = 134/314 (42%), Gaps = 74/314 (23%)

Query: 151 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDK------NFAFLEFRS 204
           LYVG++   +TE  + + F+           P  PVL++++ +D        +A++ F+ 
Sbjct: 13  LYVGDLHSDVTEAMLYEKFS-----------PAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61

Query: 205 VDETTQA---MAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKL 261
             +  +A   M FD  + +G+ ++I              +PS+   GV +         +
Sbjct: 62  PADAERALDTMNFD--VIKGKPIRIM---------WSQRDPSLRKSGVGN---------V 101

Query: 262 FIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLN 321
           FI  L   +++  + +  ++FG + +  +V D     SKGYAF  +      D+AI  +N
Sbjct: 102 FIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMN 159

Query: 322 GMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVL 381
           GM L D+K+ V R                            + ++G    E   +     
Sbjct: 160 GMLLNDRKVFVGR---------------------FKSRKEREAELGAKAKEFTNVYIKNF 198

Query: 382 PEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKA 441
            EE +DDE  +E+        S++G   S+++ R  +G +  G G  FV +    D  KA
Sbjct: 199 GEE-VDDESLKELF-------SQFGKTLSVKVMRDPNG-KSKGFG--FVSYEKHEDANKA 247

Query: 442 MQGLTGRKFANRVV 455
           ++ + G++ + +++
Sbjct: 248 VEEMNGKEISGKII 261



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 78/348 (22%), Positives = 143/348 (41%), Gaps = 65/348 (18%)

Query: 115 QIPATA--LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPF-----GITEEAMMD 167
           Q PA A   L TM  D   +   P+ ++ SQ     R+  VGN+        I  +A+ D
Sbjct: 60  QQPADAERALDTMNFD--VIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYD 117

Query: 168 FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEF-------RSVDETTQAMAFDGIIFQ 220
            F+A    G +        +    N  K +AF+ F       +++++    +  D  +F 
Sbjct: 118 TFSA---FGNILSCK----VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 221 GQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLT 280
           G+  K R+  + +      E  +VY+      V                 +D+ +KEL +
Sbjct: 171 GR-FKSRKEREAELGAKAKEFTNVYIKNFGEEV-----------------DDESLKELFS 212

Query: 281 SFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK 340
            FG   +  +++D   G SKG+ F  Y      ++A+  +NG ++  K + V RA    +
Sbjct: 213 QFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271

Query: 341 NATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRD 400
                   Q  +  +   L   Q ++  +    L + N+   ++ +DDE+       +R 
Sbjct: 272 -------RQAELKRKFEQL--KQERISRYQGVNLYIKNL---DDTIDDEK-------LRK 312

Query: 401 ECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGR 448
           E S +G + S ++   ++     G G  FV F+S  +  KA+  + GR
Sbjct: 313 EFSPFGSITSAKV--MLEDGRSKGFG--FVCFSSPEEATKAVTEMNGR 356



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           L+I  L + ++D+++++  + FG + +  ++ +   G SKG+ F  +       +A+  +
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 321 NGMQLGDKKLLVQRA 335
           NG  +G K L V  A
Sbjct: 354 NGRIVGSKPLYVALA 368


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 69/314 (21%), Positives = 134/314 (42%), Gaps = 74/314 (23%)

Query: 151 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDK------NFAFLEFRS 204
           LYVG++   +TE  + + F+           P  PVL++++ +D        +A++ F+ 
Sbjct: 13  LYVGDLHSDVTEAMLYEKFS-----------PAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61

Query: 205 VDETTQA---MAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKL 261
             +  +A   M FD  + +G+ ++I              +PS+   GV +         +
Sbjct: 62  PADAERALDTMNFD--VIKGKPIRIM---------WSQRDPSLRKSGVGN---------V 101

Query: 262 FIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLN 321
           FI  L   +++  + +  ++FG + +  +V D     SKGYAF  +      D+AI  +N
Sbjct: 102 FIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMN 159

Query: 322 GMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVL 381
           GM L D+K+ V R                            + ++G    E   +     
Sbjct: 160 GMLLNDRKVFVGR---------------------FKSRKEREAELGAKAKEFTNVYIKNF 198

Query: 382 PEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKA 441
            EE +DDE  +E+        S++G   S+++ R  +G +  G G  FV +    D  KA
Sbjct: 199 GEE-VDDESLKELF-------SQFGKTLSVKVMRDPNG-KSKGFG--FVSYEKHEDANKA 247

Query: 442 MQGLTGRKFANRVV 455
           ++ + G++ + +++
Sbjct: 248 VEEMNGKEISGKII 261



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 78/348 (22%), Positives = 143/348 (41%), Gaps = 65/348 (18%)

Query: 115 QIPATA--LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPF-----GITEEAMMD 167
           Q PA A   L TM  D   +   P+ ++ SQ     R+  VGN+        I  +A+ D
Sbjct: 60  QQPADAERALDTMNFD--VIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYD 117

Query: 168 FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEF-------RSVDETTQAMAFDGIIFQ 220
            F+A    G +        +    N  K +AF+ F       +++++    +  D  +F 
Sbjct: 118 TFSA---FGNILSCK----VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170

Query: 221 GQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLT 280
           G+  K R+  + +      E  +VY+      V                 +D+ +KEL +
Sbjct: 171 GR-FKSRKEREAELGAKAKEFTNVYIKNFGEEV-----------------DDESLKELFS 212

Query: 281 SFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK 340
            FG   +  +++D   G SKG+ F  Y      ++A+  +NG ++  K + V RA    +
Sbjct: 213 QFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271

Query: 341 NATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRD 400
                   Q  +  +   L   Q ++  +    L + N+   ++ +DDE+       +R 
Sbjct: 272 -------RQAELKRKFEQL--KQERISRYQGVNLYIKNL---DDTIDDEK-------LRK 312

Query: 401 ECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGR 448
           E S +G + S ++   ++     G G  FV F+S  +  KA+  + GR
Sbjct: 313 EFSPFGSITSAKV--MLEDGRSKGFG--FVCFSSPEEATKAVTEMNGR 356



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           L+I  L + ++D+++++  + FG + +  ++ +   G SKG+ F  +       +A+  +
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353

Query: 321 NGMQLGDKKLLVQRA 335
           NG  +G K L V  A
Sbjct: 354 NGRIVGSKPLYVALA 368


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 46/183 (25%), Positives = 81/183 (44%), Gaps = 13/183 (7%)

Query: 149 RRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDET 208
           + LYVGN+   +TE  ++  F+   ++G       N  + +    +  + F+EF      
Sbjct: 7   KTLYVGNLSRDVTEALILQLFS---QIGPCK----NCKMIMDTAGNDPYCFVEFHEHRHA 59

Query: 209 TQAMA-FDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLP 267
             A+A  +G    G+ +K+    ++   P  S+        VVST        +F+G L 
Sbjct: 60  AAALAAMNGRKIMGKEVKV----NWATTPS-SQKKDTSSSTVVSTQRSQDHFHVFVGDLS 114

Query: 268 NYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGD 327
             +  + +K     FG +    +VKD ATG SKGY F  + +    + AI  + G  LG 
Sbjct: 115 PEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGG 174

Query: 328 KKL 330
           +++
Sbjct: 175 RQI 177



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 26/199 (13%)

Query: 261 LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGL 320
           L++G L   + +  + +L +  GP K   ++ D+A   +  Y F E+ +      A+A +
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAG--NDPYCFVEFHEHRHAAAALAAM 66

Query: 321 NGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMV 380
           NG ++  K++ V  A+             TP         SSQ +     T V    +  
Sbjct: 67  NGRKIMGKEVKVNWAT-------------TP---------SSQKKDTSSSTVVSTQRSQD 104

Query: 381 LPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQK 440
                + D   E   ED++   + +G +    + + +   +  G G  FV F + +D + 
Sbjct: 105 HFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYG--FVSFFNKWDAEN 162

Query: 441 AMQGLTGRKFANRVVVTKY 459
           A+Q + G+    R + T +
Sbjct: 163 AIQQMGGQWLGGRQIRTNW 181



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 12/76 (15%)

Query: 151 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQ 210
           +Y G +  G+TE+ M   F           +P   ++ +++  DK ++F+ F S +    
Sbjct: 216 VYCGGVTSGLTEQLMRQTF-----------SPFGQIMEIRVFPDKGYSFVRFNSHESAAH 264

Query: 211 A-MAFDGIIFQGQSLK 225
           A ++ +G   +G  +K
Sbjct: 265 AIVSVNGTTIEGHVVK 280


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 4/101 (3%)

Query: 13  ENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEE 72
           E ++ER++ENR R+R   R R R+R+RR R R+R    +R   R RR+      R  ++E
Sbjct: 403 ERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDE 462

Query: 73  ----HGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKA 109
               H    R    EK+K   K     PP  +   P +  A
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAA 503



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 12  NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR-----RNRDQRSASRDR-RRRSKPL 65
           N   Q  + E  H  R   R R R+R+ R R R+R     R R++R   R+R R   +  
Sbjct: 387 NFRVQYTETEPYHNYRE--RERERERENRQRERERERERDRERERRQREREREREHERDK 444

Query: 66  TRGAKEEHGGLIRSPRHEKKKKVR 89
            R  ++E     R+ R EK ++ R
Sbjct: 445 ERQRRKEEWERERAKRDEKDRQHR 468


>gi|41393554 LUC7-like isoform b [Homo sapiens]
          Length = 371

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 31/65 (47%), Positives = 41/65 (63%), Gaps = 3/65 (4%)

Query: 15  KQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHG 74
           ++ER++E R  +RS SR+R R   RRSRSRDRR R  RS SR+RR+ S+  +R     H 
Sbjct: 247 REEREREERLSRRSGSRTRDR---RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHR 303

Query: 75  GLIRS 79
              RS
Sbjct: 304 SRSRS 308



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 31/79 (39%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 5   DEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSK 63
           D    +  + ++ R +     +R  SRSRSRDR RR RSR R  +R  R ASRDR  + K
Sbjct: 266 DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325

Query: 64  -PLTRGAKEEHGGLIRSPR 81
               R ++EE     RS R
Sbjct: 326 FSRERASREESWESGRSER 344



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 7/85 (8%)

Query: 5   DEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKP 64
           D+  + + E +++R+++   R+    R     R+  SR+RDRR    RS SRDRRRR   
Sbjct: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR----RSRSRDRRRRR-- 279

Query: 65  LTRGAKEEHGGLIRSPRHEKKKKVR 89
            +R    E   L RS   ++ ++ R
Sbjct: 280 -SRSTSRERRKLSRSRSRDRHRRHR 303



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 8   ERQLNENKQERD-KENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLT 66
           ER+  E    R     R R+RS SR R R R+ RS SR+RR +  RS SRDR RR +  +
Sbjct: 249 EREREERLSRRSGSRTRDRRRSRSRDRRR-RRSRSTSRERR-KLSRSRSRDRHRRHRSRS 306

Query: 67  RGAKEEH 73
           R     H
Sbjct: 307 RSHSRGH 313



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 5/60 (8%)

Query: 9   RQLNENKQERDKENRHRKRSHSRSRSRDRKR----RSRSRDRRNRDQ-RSASRDRRRRSK 63
           R  +  +  R   +R R+R  SRS SR+R++    RSR R RR+R + RS SR  RR S+
Sbjct: 259 RSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASR 318


>gi|8922297 LUC7-like isoform a [Homo sapiens]
          Length = 325

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 31/65 (47%), Positives = 41/65 (63%), Gaps = 3/65 (4%)

Query: 15  KQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHG 74
           ++ER++E R  +RS SR+R R   RRSRSRDRR R  RS SR+RR+ S+  +R     H 
Sbjct: 247 REEREREERLSRRSGSRTRDR---RRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHR 303

Query: 75  GLIRS 79
              RS
Sbjct: 304 SRSRS 308



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 7/85 (8%)

Query: 5   DEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKP 64
           D+  + + E +++R+++   R+    R     R+  SR+RDRR    RS SRDRRRR   
Sbjct: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR----RSRSRDRRRRR-- 279

Query: 65  LTRGAKEEHGGLIRSPRHEKKKKVR 89
            +R    E   L RS   ++ ++ R
Sbjct: 280 -SRSTSRERRKLSRSRSRDRHRRHR 303



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 1/60 (1%)

Query: 5   DEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSK 63
           D    +  + ++ R +     +R  SRSRSRDR RR RSR R  +R  R ASRDR  + K
Sbjct: 266 DRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK 325



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 8   ERQLNENKQERD-KENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLT 66
           ER+  E    R     R R+RS SR R R R+ RS SR+RR +  RS SRDR RR +  +
Sbjct: 249 EREREERLSRRSGSRTRDRRRSRSRDRRR-RRSRSTSRERR-KLSRSRSRDRHRRHRSRS 306

Query: 67  RGAKEEH 73
           R     H
Sbjct: 307 RSHSRGH 313



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 1/60 (1%)

Query: 9   RQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR-RNRDQRSASRDRRRRSKPLTR 67
           R  +  +  R   +R R+R  SRS SR+R++ SRSR R R+R  RS SR   R  +  +R
Sbjct: 259 RSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASR 318



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 10/68 (14%)

Query: 6   EFERQLNENKQERDKENRH---RKRSHSRSRSRDRKR----RSRSRDRRNRDQ---RSAS 55
           E E +L+     R ++ R    R R   RSRS  R+R    RSRSRDR  R +   RS S
Sbjct: 251 EREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHS 310

Query: 56  RDRRRRSK 63
           R  RR S+
Sbjct: 311 RGHRRASR 318


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 26/85 (30%), Positives = 45/85 (52%)

Query: 6   EFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPL 65
           E ER+  + ++ + K+ R +KR   R R ++R +R R R +R +++R   R+R R+ +  
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181

Query: 66  TRGAKEEHGGLIRSPRHEKKKKVRK 90
            R  KE         +  +KKK RK
Sbjct: 182 ERERKERRERKKERKKERRKKKERK 206



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 22/78 (28%), Positives = 46/78 (58%), Gaps = 4/78 (5%)

Query: 13  ENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEE 72
           E K+ER K+ + +++   R + R+RKR+ R + R+ R ++    +RR+R K   +  +++
Sbjct: 53  ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK----ERRKRKKEKKKRERKQ 108

Query: 73  HGGLIRSPRHEKKKKVRK 90
            G   R  + E+K++ R+
Sbjct: 109 RGRRERKKKKERKERERE 126



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%)

Query: 9   RQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRG 68
           R+  + K+ER+KE R R+R     + R ++ R + R+R+ +++    ++RR + +   + 
Sbjct: 41  REREKRKREREKE-RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99

Query: 69  AKEEHGGLIRSPRHEKKKKVRK 90
            K++     R  R  KKKK RK
Sbjct: 100 EKKKRERKQRGRRERKKKKERK 121



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 4/89 (4%)

Query: 6   EFERQLNENKQE----RDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRR 61
           E E+Q  E +++    R KE + R+R     R R +K+  + R+R N+ +R   R +RR+
Sbjct: 81  EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140

Query: 62  SKPLTRGAKEEHGGLIRSPRHEKKKKVRK 90
            K      +E+  G     R ++KK+ R+
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEERE 169



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 8/88 (9%)

Query: 8   ERQLNENKQERDKENRHRKRSHSRSRSRDRKR-----RSRSRDRRNRDQRSASRDRRRRS 62
           ER+  + ++ER++EN+ R+    R R + RK+     R R ++R  R+++   R +  R 
Sbjct: 113 ERKKKKERKERERENKQRRE---RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169

Query: 63  KPLTRGAKEEHGGLIRSPRHEKKKKVRK 90
           K   R  KE      R  R E+KK+ +K
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKK 197



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 6   EFERQLNENKQE----------RDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSAS 55
           E ER+    K+E          +++E + ++R   R   R+++RR R ++++ R+++   
Sbjct: 51  EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110

Query: 56  RDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRK 90
           R  R++ K      +E      R  +  +KKK RK
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 10/87 (11%)

Query: 8   ERQLNENKQ----ERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSK 63
           E++  E KQ    ER K+   ++R     + R+RKR+ R R ++ R +R   ++R +R +
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-RKKKRRKERKREKERGKRER 158

Query: 64  PLTRGAKEEHGGLIRSPRHEKKKKVRK 90
              +  KEE     R  + E+ +K RK
Sbjct: 159 KRKKRKKEE-----REKKRERNRKERK 180



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 5   DEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKP 64
           +E E++   N++ER KE   R+R   R R ++RK+  R +  R +D+++  +   +  +P
Sbjct: 166 EEREKKRERNRKERKKE---RERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP 222

Query: 65  LTRGA 69
           L   A
Sbjct: 223 LRESA 227



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 15/55 (27%), Positives = 32/55 (58%), Gaps = 1/55 (1%)

Query: 8   ERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRS 62
           +R+  E +++R++  + RK+   R   R+RK + R ++RR + +R   R   R++
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERK-KERKKERRKKKERKKDRKTDRQT 215



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 4/61 (6%)

Query: 8   ERQLNENKQERD-KENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLT 66
           ER   E K+ER+ KE R RK+   + R   RK++ R +DR+   Q  +   R  R     
Sbjct: 173 ERNRKERKKERERKERRERKKERKKER---RKKKERKKDRKTDRQTDSQVFRPLRESAFN 229

Query: 67  R 67
           R
Sbjct: 230 R 230



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 6   EFERQLNENKQE-RDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKP 64
           E ER   E K++ R KE R +KR  +R   ++RK+    ++RR R +      R+++ + 
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKERRERKKERKKERRKKKERK 206

Query: 65  LTRGAKEEHGGLIRSPRHE 83
             R    +    +  P  E
Sbjct: 207 KDRKTDRQTDSQVFRPLRE 225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,748,908
Number of Sequences: 37866
Number of extensions: 903546
Number of successful extensions: 11361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 387
Number of HSP's successfully gapped in prelim test: 199
Number of HSP's that attempted gapping in prelim test: 4685
Number of HSP's gapped (non-prelim): 3751
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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