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Search of human proteins with 6005715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005715 solute carrier family 6 (amino acid transporter),
member 14 [Homo sapiens]
(642 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005715 solute carrier family 6 (amino acid transporter), mem... 1328 0.0
gi|92859670 solute carrier family 6 (neurotransmitter transporte... 644 0.0
gi|134304856 solute carrier family 6, member 7 [Homo sapiens] 551 e-157
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap... 525 e-149
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap... 525 e-149
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap... 525 e-149
gi|188528618 solute carrier family 6 (neurotransmitter transport... 488 e-138
gi|4557046 solute carrier family 6 member 2 [Homo sapiens] 483 e-136
gi|171184408 solute carrier family 6 (neurotransmitter transport... 479 e-135
gi|171184406 solute carrier family 6 (neurotransmitter transport... 479 e-135
gi|171184404 solute carrier family 6 (neurotransmitter transport... 479 e-135
gi|4507041 solute carrier family 6 (neurotransmitter transporter... 476 e-134
gi|21361581 solute carrier family 6 (neurotransmitter transporte... 471 e-133
gi|7657587 solute carrier family 6 (neurotransmitter transporter... 461 e-130
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi... 456 e-128
gi|197276623 solute carrier family 6 (neurotransmitter transport... 456 e-128
gi|54607094 solute carrier family 6 (neurotransmitter transporte... 456 e-128
gi|4507043 solute carrier family 6 member 4 [Homo sapiens] 454 e-127
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa... 440 e-123
gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 374 e-103
gi|194018524 solute carrier family 6, member 18 [Homo sapiens] 373 e-103
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa... 364 e-100
gi|51468073 solute carrier family 6, member 19 [Homo sapiens] 355 9e-98
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s... 326 4e-89
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s... 274 2e-73
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s... 273 4e-73
gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 242 7e-64
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ... 205 1e-52
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s... 182 6e-46
gi|197276625 solute carrier family 6 (neurotransmitter transport... 154 2e-37
>gi|6005715 solute carrier family 6 (amino acid transporter), member
14 [Homo sapiens]
Length = 642
Score = 1328 bits (3436), Expect = 0.0
Identities = 642/642 (100%), Positives = 642/642 (100%)
Query: 1 MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVW 60
MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVW
Sbjct: 1 MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVW 60
Query: 61 RFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGIT 120
RFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGIT
Sbjct: 61 RFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGIT 120
Query: 121 MVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNK 180
MVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNK
Sbjct: 121 MVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNK 180
Query: 181 GIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLA 240
GIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLA
Sbjct: 181 GIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLA 240
Query: 241 LCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQ 300
LCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQ
Sbjct: 241 LCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQ 300
Query: 301 SNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVF 360
SNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVF
Sbjct: 301 SNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVF 360
Query: 361 AGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLG 420
AGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLG
Sbjct: 361 AGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLG 420
Query: 421 LDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHF 480
LDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHF
Sbjct: 421 LDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHF 480
Query: 481 CAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAI 540
CAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAI
Sbjct: 481 CAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAI 540
Query: 541 FIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCC 600
FIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCC
Sbjct: 541 FIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCC 600
Query: 601 RPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE 642
RPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE
Sbjct: 601 RPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE 642
>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
glycine), member 5 [Homo sapiens]
Length = 797
Score = 644 bits (1660), Expect = 0.0
Identities = 322/603 (53%), Positives = 415/603 (68%), Gaps = 17/603 (2%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
+ DEN+ RGNWS K D++LSM+GYAVGLGNVWRFPYL + NGGGAFLIPY +MLALAGLP
Sbjct: 184 QGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLP 243
Query: 89 LFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQ 148
+FFLE SLGQFAS GPVSVW+ +P QG GI M++IS+ + IYYNVII Y+L+Y+FASF
Sbjct: 244 IFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFV 303
Query: 149 SELPWKNCSS-WSDKNCSRSP--IVTHCNVSTVNKGIQEIIQMNKSWVDIN---NFTCIN 202
S LPW +C++ W+ C ++ C +S K IQ+ S + N T +N
Sbjct: 304 SVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPK-----IQIKNSTFCMTAYPNVTMVN 358
Query: 203 -GSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSS 261
S+ + SE+Y+ L+ S+G+ G I W LALCL LAW+IV A+L KGIK+S
Sbjct: 359 FTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTS 418
Query: 262 GKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFY 321
GKVVYFTA FPYVVL+ILL+RG TL GA GI Y+I + + KL +A VWKDAATQIF+
Sbjct: 419 GKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPK--WEKLTDATVWKDAATQIFF 476
Query: 322 SLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVS 381
SLS AWGGL+ LSSYNKF NNC+ D ++V TN TS+FAGF IFS++G MA+ +
Sbjct: 477 SLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIE 536
Query: 382 QVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPK 441
V G +AF+ YPEAL +LP PFW+I+FF MLLTLGLD+ FA+IETI T+I D FPK
Sbjct: 537 NVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPK 596
Query: 442 VMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIY 501
++ + TLGCC+ F++G +TQ GIY L+D + A + ++I AI ELVGI ++Y
Sbjct: 597 YLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVY 656
Query: 502 GGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDW 561
G RF ED EMMIG + IF W+ CW +TP +L I +S Q+ YG+ YP+W
Sbjct: 657 GLQRFCEDIEMMIGFQPNIF---WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNW 713
Query: 562 GVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDM 621
+ LGW M+ +IWIPIM +IK+ A G +RL C P +WGP+L QHRGERYK+M
Sbjct: 714 SMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNM 773
Query: 622 VDP 624
+DP
Sbjct: 774 IDP 776
>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
Length = 636
Score = 551 bits (1421), Expect = e-157
Identities = 279/609 (45%), Positives = 388/609 (63%), Gaps = 45/609 (7%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
RGNW+ K D+LLS IGY VGLGNVWRFPY Y+NGGGAFL+PY +MLA+ G+PLFFLE S
Sbjct: 37 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELS 96
Query: 96 LGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKN 155
LGQF+SLGP++VW+I PLF+G G M+LI V IYYN+IIAY L+Y+FAS S+LPW++
Sbjct: 97 LGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEH 156
Query: 156 CSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSE 215
C +W + C V+K + +N TC PSE
Sbjct: 157 CGNWWNTEL--------CLEHRVSKDGNGALPLN--------LTCTVS---------PSE 191
Query: 216 QYWNKVAL--QRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPY 273
+YW++ L Q S G+ G I W L LCLLLAW+IV + KG+KSSGKVVYFTA FPY
Sbjct: 192 EYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPY 251
Query: 274 VVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVAL 333
++LL+LLVRG TL GA KGI +Y+ Q F L ++VW +AA QIFYSL V +GGL+
Sbjct: 252 LILLMLLVRGVTLPGAWKGIQFYLTPQ--FHHLLSSKVWIEAALQIFYSLGVGFGGLLTF 309
Query: 334 SSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFI 393
+SYN F N + D +V L N +TS+ AGFAIFS+LG+M+ G V QV K+G LAF+
Sbjct: 310 ASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFV 369
Query: 394 AYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLG 453
YP+A+ LP PFWS LFFFMLLTLGLDSQFA +ETI T + D FP ++ + +
Sbjct: 370 VYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGL 429
Query: 454 CCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMM 513
C+ ++L+GL+ T G+YW+ L+D + A +G+++ I + + +YG RF D MM
Sbjct: 430 ICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMM 489
Query: 514 IGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFC 573
+G K L++RACW ++P L+A+ ++S+V++ YG+ +P W LG M +
Sbjct: 490 LGFKP---GLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLS 546
Query: 574 IIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDMVDPKKEADHEIP 633
+ IP ++ +++ +G++++RL RPA +WGP LE++R Y +
Sbjct: 547 CLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMY-------------VA 593
Query: 634 TVSGSRKPE 642
T++GS+ P+
Sbjct: 594 TLAGSQSPK 602
>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
sapiens]
Length = 633
Score = 525 bits (1353), Expect = e-149
Identities = 266/607 (43%), Positives = 390/607 (64%), Gaps = 22/607 (3%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
+ D+N RGNW + +++L+ +GYAVGLGNVWRFPYL Y NGGGAF+ PY IML G+P
Sbjct: 20 KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIP 79
Query: 89 LFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQ 148
LFF+E S GQFAS G + VWRI P+F+GVG M+++S ++ IYYNV+I + YY F+S
Sbjct: 80 LFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMT 139
Query: 149 SELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIY 207
LPW C++ W+ +C + ++ N++ N + N S + N + S
Sbjct: 140 HVLPWAYCNNPWNTHDC--AGVLDASNLT--NGSRPAALPSNLS--HLLNHSLQRTS--- 190
Query: 208 QPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYF 267
PSE+YW L+ S + G + L CL ++WL+V L +G+KSSGKVVYF
Sbjct: 191 -----PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYF 245
Query: 268 TALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAW 327
TA FPYVVL IL VRG TLEGA GI YY+ Q + K+ EA+VW DAA+QIFYSL AW
Sbjct: 246 TATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQ--WDKILEAKVWGDAASQIFYSLGCAW 303
Query: 328 GGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSG 387
GGL+ ++SYNKF NNC+ D++++ +TNC TSV+AGF IFSILG MA+ G +VS+V G
Sbjct: 304 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 363
Query: 388 FDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQD-LFPKVMKKM 446
LAF+AYPEAL LP P WS+LFFFML+ LGL +QF +ET+ T I D + + + +
Sbjct: 364 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK 423
Query: 447 RVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRF 506
+ +TLG + FLLG+ +QAGIYW+ L+D++ A + +++ + + V I++IYG +
Sbjct: 424 KTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNY 483
Query: 507 IEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
+D +MM+G +F ++ CW ++P ++ I +++++Q+ Y YP W VA+G
Sbjct: 484 FQDIQMMLGFPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG 540
Query: 567 WCMIVFCIIWIPIMAIIKIIQAKGN-IFQRLISCCRPASNWGPYLEQHRGERYKDMVDPK 625
+ M + ++ IP+ A+ ++ + G+ + QRL + +P+ +WGP L +HR RY + P
Sbjct: 541 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS 600
Query: 626 KEADHEI 632
E E+
Sbjct: 601 PEDGFEV 607
>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
sapiens]
Length = 706
Score = 525 bits (1353), Expect = e-149
Identities = 266/607 (43%), Positives = 390/607 (64%), Gaps = 22/607 (3%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
+ D+N RGNW + +++L+ +GYAVGLGNVWRFPYL Y NGGGAF+ PY IML G+P
Sbjct: 93 KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIP 152
Query: 89 LFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQ 148
LFF+E S GQFAS G + VWRI P+F+GVG M+++S ++ IYYNV+I + YY F+S
Sbjct: 153 LFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMT 212
Query: 149 SELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIY 207
LPW C++ W+ +C + ++ N++ N + N S + N + S
Sbjct: 213 HVLPWAYCNNPWNTHDC--AGVLDASNLT--NGSRPAALPSNLS--HLLNHSLQRTS--- 263
Query: 208 QPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYF 267
PSE+YW L+ S + G + L CL ++WL+V L +G+KSSGKVVYF
Sbjct: 264 -----PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYF 318
Query: 268 TALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAW 327
TA FPYVVL IL VRG TLEGA GI YY+ Q + K+ EA+VW DAA+QIFYSL AW
Sbjct: 319 TATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQ--WDKILEAKVWGDAASQIFYSLGCAW 376
Query: 328 GGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSG 387
GGL+ ++SYNKF NNC+ D++++ +TNC TSV+AGF IFSILG MA+ G +VS+V G
Sbjct: 377 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 436
Query: 388 FDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQD-LFPKVMKKM 446
LAF+AYPEAL LP P WS+LFFFML+ LGL +QF +ET+ T I D + + + +
Sbjct: 437 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK 496
Query: 447 RVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRF 506
+ +TLG + FLLG+ +QAGIYW+ L+D++ A + +++ + + V I++IYG +
Sbjct: 497 KTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNY 556
Query: 507 IEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
+D +MM+G +F ++ CW ++P ++ I +++++Q+ Y YP W VA+G
Sbjct: 557 FQDIQMMLGFPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG 613
Query: 567 WCMIVFCIIWIPIMAIIKIIQAKGN-IFQRLISCCRPASNWGPYLEQHRGERYKDMVDPK 625
+ M + ++ IP+ A+ ++ + G+ + QRL + +P+ +WGP L +HR RY + P
Sbjct: 614 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS 673
Query: 626 KEADHEI 632
E E+
Sbjct: 674 PEDGFEV 680
>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
sapiens]
Length = 652
Score = 525 bits (1353), Expect = e-149
Identities = 266/607 (43%), Positives = 390/607 (64%), Gaps = 22/607 (3%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
+ D+N RGNW + +++L+ +GYAVGLGNVWRFPYL Y NGGGAF+ PY IML G+P
Sbjct: 39 KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIP 98
Query: 89 LFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQ 148
LFF+E S GQFAS G + VWRI P+F+GVG M+++S ++ IYYNV+I + YY F+S
Sbjct: 99 LFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMT 158
Query: 149 SELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIY 207
LPW C++ W+ +C + ++ N++ N + N S + N + S
Sbjct: 159 HVLPWAYCNNPWNTHDC--AGVLDASNLT--NGSRPAALPSNLS--HLLNHSLQRTS--- 209
Query: 208 QPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYF 267
PSE+YW L+ S + G + L CL ++WL+V L +G+KSSGKVVYF
Sbjct: 210 -----PSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYF 264
Query: 268 TALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAW 327
TA FPYVVL IL VRG TLEGA GI YY+ Q + K+ EA+VW DAA+QIFYSL AW
Sbjct: 265 TATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQ--WDKILEAKVWGDAASQIFYSLGCAW 322
Query: 328 GGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSG 387
GGL+ ++SYNKF NNC+ D++++ +TNC TSV+AGF IFSILG MA+ G +VS+V G
Sbjct: 323 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 382
Query: 388 FDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQD-LFPKVMKKM 446
LAF+AYPEAL LP P WS+LFFFML+ LGL +QF +ET+ T I D + + + +
Sbjct: 383 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK 442
Query: 447 RVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRF 506
+ +TLG + FLLG+ +QAGIYW+ L+D++ A + +++ + + V I++IYG +
Sbjct: 443 KTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNY 502
Query: 507 IEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
+D +MM+G +F ++ CW ++P ++ I +++++Q+ Y YP W VA+G
Sbjct: 503 FQDIQMMLGFPPPLF---FQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG 559
Query: 567 WCMIVFCIIWIPIMAIIKIIQAKGN-IFQRLISCCRPASNWGPYLEQHRGERYKDMVDPK 625
+ M + ++ IP+ A+ ++ + G+ + QRL + +P+ +WGP L +HR RY + P
Sbjct: 560 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS 619
Query: 626 KEADHEI 632
E E+
Sbjct: 620 PEDGFEV 626
>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
GABA), member 1 [Homo sapiens]
Length = 599
Score = 488 bits (1257), Expect = e-138
Identities = 241/573 (42%), Positives = 350/573 (61%), Gaps = 41/573 (7%)
Query: 35 DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94
DR W + D+L+S +GYA+GLGNVWRFPYL NGGGAFLIPY + L AG+PLF LEC
Sbjct: 43 DRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLEC 102
Query: 95 SLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154
SLGQ+ S+G + VW++ P+F+GVG+ ++S ++ IYY VII++++YY++ SF + LPWK
Sbjct: 103 SLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWK 162
Query: 155 NCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLP 213
C + W+ C N S V+ N T
Sbjct: 163 QCDNPWNTDRCF----------------------SNYSMVNTTNMTS------------A 188
Query: 214 SEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPY 273
++W + Q + G+++ G I W LA+ L +AW++V ++KG+ +GKVVYF+A +PY
Sbjct: 189 VVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPY 248
Query: 274 VVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVAL 333
++L+IL RG TL GA +GI +YI NF KL ++EVW DAATQIF+S + G L+AL
Sbjct: 249 IMLIILFFRGVTLPGAKEGILFYI--TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIAL 306
Query: 334 SSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFI 393
SYN F NN + D+I+VC N TS+FAGF IFSI+G MAH++ + ++ V SG LAF+
Sbjct: 307 GSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFL 366
Query: 394 AYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLG 453
AYPEA+ QLP P W+ILFF MLL LG+DSQF ++E T + D +P++++ R
Sbjct: 367 AYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAA 426
Query: 454 CCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIEDTEM 512
C++ +L+GL +TQ GIY L D++ A G +L E V I W YG NRF ++ +
Sbjct: 427 VCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQE 486
Query: 513 MIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVF 572
M+G++ I WW+ CW TPI++ +FI+S VQ G +P WG +GW M +
Sbjct: 487 MVGSRPCI---WWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALS 543
Query: 573 CIIWIPIMAIIKIIQAKGNIFQRLISCCRPASN 605
++ IP + KG++ QR+ +P+ +
Sbjct: 544 SMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSED 576
>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
Length = 617
Score = 483 bits (1243), Expect = e-136
Identities = 242/564 (42%), Positives = 349/564 (61%), Gaps = 30/564 (5%)
Query: 34 QDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLE 93
Q R W KK D+LLS++G+AV L NVWRFPYL Y NGGGAFLIPY + L +AG+PLF++E
Sbjct: 54 QPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYME 113
Query: 94 CSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPW 153
+LGQ+ G +VW+I P F+GVG ++LI+++V YYNVIIA+SLYY+F+SF LPW
Sbjct: 114 LALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPW 173
Query: 154 KNCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQL 212
+C +W+ NC+ ++ + K + + +E Y+ G L
Sbjct: 174 TDCGHTWNSPNCTDPKLLNGSVLGNHTK--------------YSKYKFTPAAEFYERGVL 219
Query: 213 PSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFP 272
L SSG+++ G+ W L LCL++ +++ +L+KG+K+SGKVV+ TA P
Sbjct: 220 ---------HLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLP 270
Query: 273 YVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVA 332
Y VL +LLV G TL GAS GI+ Y+ +F +LKEA VW DAATQIF+SL +G L+A
Sbjct: 271 YFVLFVLLVHGVTLPGASNGINAYL--HIDFYRLKEATVWIDAATQIFFSLGAGFGVLIA 328
Query: 333 LSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAF 392
+SYNKF NNC+ DA++ NC+TS +GFAIFSILG+MAH + V G L F
Sbjct: 329 FASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVF 388
Query: 393 IAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITL 452
I YPEA++ L G FW+++FF MLL LGLDS +E + T + D F +V+K+ R T
Sbjct: 389 ILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDF-QVLKRHRKLFTF 447
Query: 453 GCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEM 512
G FLL L C+T+ GIY + L+D F AG IL A ++E +G+ W YG +RF D +
Sbjct: 448 GVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQ 507
Query: 513 MIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVF 572
M+G + L+WR CW ++P L+ + + S++ F Y +P W +GW + +
Sbjct: 508 MMGFRP---GLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALS 564
Query: 573 CIIWIPIMAIIKIIQAKGNIFQRL 596
++ +PI I K + +G++++RL
Sbjct: 565 SMVLVPIYVIYKFLSTQGSLWERL 588
>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 479 bits (1232), Expect = e-135
Identities = 246/602 (40%), Positives = 370/602 (61%), Gaps = 40/602 (6%)
Query: 18 VSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIP 77
V E + D+ +DRG W+ K +++LS+ G +GLGNVWRFPYL Y NGGGAF IP
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 78 YAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVII 136
Y I + G+P+FFLE +LGQ+ S G V+ WR I PLFQG+G+ V+I ++ +YY +I+
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 137 AYSLYYMFASFQSELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDI 195
A++L+Y+F+SF SELPW C++ W+ ++C+ + H TV
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCT--DFLNHSGAGTVTP--------------F 181
Query: 196 NNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALF 255
NFT P ++W + L +SG+++ G + W LALCLLLAW+I ++
Sbjct: 182 ENFTS------------PVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIW 229
Query: 256 KGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDA 315
KG+KS+GKVVYFTA FPY++L+ILL+RG TL GA +GI YY+ + + +LK+ +VW DA
Sbjct: 230 KGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYL--KPDLFRLKDPQVWMDA 287
Query: 316 ATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHI 375
TQIF+S ++ G L AL SYNK+ NNC+ D I +C N TS AGF +FSILG M+
Sbjct: 288 GTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQE 347
Query: 376 SGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTI 435
G +S+V +SG LAFIA+P+A+ +P WS LFF ML+ LGLDSQF +E + T
Sbjct: 348 QGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTAS 407
Query: 436 QDLFPKVMKK--MRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFC-AGWGILIAAIL 492
D+FP+ ++K R + L ++ +L+GL VT+ G+Y L D++ +G +L ++
Sbjct: 408 IDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLF 467
Query: 493 ELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPN 552
E+V I W+YG +RF ++ E MIG + W + W +TP L +A F++SL ++
Sbjct: 468 EVVCISWVYGADRFYDNIEDMIGYRPWPL---VKISWLFLTPGLCLATFLFSLSKYTPLK 524
Query: 553 YGAI-PYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLE 611
Y + YP WG ++GW + + ++ +P+ +I +++ +G +RL P S+ P +
Sbjct: 525 YNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSL-PQPK 583
Query: 612 QH 613
QH
Sbjct: 584 QH 585
>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 479 bits (1232), Expect = e-135
Identities = 246/602 (40%), Positives = 370/602 (61%), Gaps = 40/602 (6%)
Query: 18 VSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIP 77
V E + D+ +DRG W+ K +++LS+ G +GLGNVWRFPYL Y NGGGAF IP
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 78 YAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVII 136
Y I + G+P+FFLE +LGQ+ S G V+ WR I PLFQG+G+ V+I ++ +YY +I+
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 137 AYSLYYMFASFQSELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDI 195
A++L+Y+F+SF SELPW C++ W+ ++C+ + H TV
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCT--DFLNHSGAGTVTP--------------F 181
Query: 196 NNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALF 255
NFT P ++W + L +SG+++ G + W LALCLLLAW+I ++
Sbjct: 182 ENFTS------------PVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIW 229
Query: 256 KGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDA 315
KG+KS+GKVVYFTA FPY++L+ILL+RG TL GA +GI YY+ + + +LK+ +VW DA
Sbjct: 230 KGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYL--KPDLFRLKDPQVWMDA 287
Query: 316 ATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHI 375
TQIF+S ++ G L AL SYNK+ NNC+ D I +C N TS AGF +FSILG M+
Sbjct: 288 GTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQE 347
Query: 376 SGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTI 435
G +S+V +SG LAFIA+P+A+ +P WS LFF ML+ LGLDSQF +E + T
Sbjct: 348 QGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTAS 407
Query: 436 QDLFPKVMKK--MRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFC-AGWGILIAAIL 492
D+FP+ ++K R + L ++ +L+GL VT+ G+Y L D++ +G +L ++
Sbjct: 408 IDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLF 467
Query: 493 ELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPN 552
E+V I W+YG +RF ++ E MIG + W + W +TP L +A F++SL ++
Sbjct: 468 EVVCISWVYGADRFYDNIEDMIGYRPWPL---VKISWLFLTPGLCLATFLFSLSKYTPLK 524
Query: 553 YGAI-PYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLE 611
Y + YP WG ++GW + + ++ +P+ +I +++ +G +RL P S+ P +
Sbjct: 525 YNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSL-PQPK 583
Query: 612 QH 613
QH
Sbjct: 584 QH 585
>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 479 bits (1232), Expect = e-135
Identities = 246/602 (40%), Positives = 370/602 (61%), Gaps = 40/602 (6%)
Query: 18 VSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIP 77
V E + D+ +DRG W+ K +++LS+ G +GLGNVWRFPYL Y NGGGAF IP
Sbjct: 18 VPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 77
Query: 78 YAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVII 136
Y I + G+P+FFLE +LGQ+ S G V+ WR I PLFQG+G+ V+I ++ +YY +I+
Sbjct: 78 YFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIIL 137
Query: 137 AYSLYYMFASFQSELPWKNCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDI 195
A++L+Y+F+SF SELPW C++ W+ ++C+ + H TV
Sbjct: 138 AWALFYLFSSFTSELPWTTCNNFWNTEHCT--DFLNHSGAGTVTP--------------F 181
Query: 196 NNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALF 255
NFT P ++W + L +SG+++ G + W LALCLLLAW+I ++
Sbjct: 182 ENFTS------------PVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIW 229
Query: 256 KGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDA 315
KG+KS+GKVVYFTA FPY++L+ILL+RG TL GA +GI YY+ + + +LK+ +VW DA
Sbjct: 230 KGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYL--KPDLFRLKDPQVWMDA 287
Query: 316 ATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHI 375
TQIF+S ++ G L AL SYNK+ NNC+ D I +C N TS AGF +FSILG M+
Sbjct: 288 GTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQE 347
Query: 376 SGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTI 435
G +S+V +SG LAFIA+P+A+ +P WS LFF ML+ LGLDSQF +E + T
Sbjct: 348 QGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTAS 407
Query: 436 QDLFPKVMKK--MRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFC-AGWGILIAAIL 492
D+FP+ ++K R + L ++ +L+GL VT+ G+Y L D++ +G +L ++
Sbjct: 408 IDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLF 467
Query: 493 ELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPN 552
E+V I W+YG +RF ++ E MIG + W + W +TP L +A F++SL ++
Sbjct: 468 EVVCISWVYGADRFYDNIEDMIGYRPWPL---VKISWLFLTPGLCLATFLFSLSKYTPLK 524
Query: 553 YGAI-PYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLE 611
Y + YP WG ++GW + + ++ +P+ +I +++ +G +RL P S+ P +
Sbjct: 525 YNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSL-PQPK 583
Query: 612 QH 613
QH
Sbjct: 584 QH 585
>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
dopamine), member 3 [Homo sapiens]
Length = 620
Score = 476 bits (1226), Expect = e-134
Identities = 248/574 (43%), Positives = 350/574 (60%), Gaps = 35/574 (6%)
Query: 32 ENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFF 91
E QDR W KK D+LLS+IG+AV L NVWRFPYL Y NGGGAFL+PY + + +AG+PLF+
Sbjct: 56 EAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFY 115
Query: 92 LECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSEL 151
+E +LGQF G VW+I P+ +GVG T++LIS++V +YNVIIA++L+Y+F+SF +EL
Sbjct: 116 MELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTEL 175
Query: 152 PWKNC-SSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPG 210
PW +C +SW+ NCS + + S + G+ + G
Sbjct: 176 PWIHCNNSWNSPNCSDA---HPGDSSGDSSGLNDTF-----------------------G 209
Query: 211 QLPSEQYWNK--VALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFT 268
P+ +Y+ + + L +S G+++ G W L CL+L +++ +L+KG+K+SGKVV+ T
Sbjct: 210 TTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWIT 269
Query: 269 ALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWG 328
A PYVVL LL+RG TL GA GI Y+ +F +L EA VW DAATQ+ +SL V +G
Sbjct: 270 ATMPYVVLTALLLRGVTLPGAIDGIRAYLSV--DFYRLCEASVWIDAATQVCFSLGVGFG 327
Query: 329 GLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGF 388
L+A SSYNKF NNC+ DAIV N LTS +GF +FS LG+MA + V K G
Sbjct: 328 VLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGP 387
Query: 389 DLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRV 448
L FI YPEA+A LP W+++FF MLLTLG+DS +E++ T + D F +++ + R
Sbjct: 388 GLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRE 446
Query: 449 PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIE 508
TL L FLL L CVT GIY L+DHF AG IL ++E +G+ W YG +F +
Sbjct: 447 LFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSD 506
Query: 509 DTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWC 568
D + M G + L+WR CW +++P L+ + + S+V F P+YGA +PDW ALGW
Sbjct: 507 DIQQMTGQRP---SLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWV 563
Query: 569 MIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRP 602
+ + +PI A K G+ ++L P
Sbjct: 564 IATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAP 597
>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
GABA), member 13 [Homo sapiens]
Length = 602
Score = 471 bits (1213), Expect = e-133
Identities = 241/583 (41%), Positives = 356/583 (61%), Gaps = 40/583 (6%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
E D +RG+W+ K +++LS+ G +GLGNVWRFPYL Y NGGGAF IPY + L G+P
Sbjct: 25 EEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIP 84
Query: 89 LFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASF 147
+F LE +LGQ+ S G V+ WR I P+F+G+G +I I + +YY +++A++L+Y+F+SF
Sbjct: 85 VFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSF 144
Query: 148 QSELPWKNC-SSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEI 206
+LPW C W+ ++C E + N S +NG+
Sbjct: 145 TIDLPWGGCYHEWNTEHC------------------MEFQKTNGS---------LNGTS- 176
Query: 207 YQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVY 266
+ P ++W + L+ S G+ G + W LALCLLLAW+I ++KG+KS+GKVVY
Sbjct: 177 -ENATSPVIEFWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVY 235
Query: 267 FTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVA 326
FTA FPY++L++LL+RG TL GA++GI +Y+ N T+L + +VW DA TQIF+S ++
Sbjct: 236 FTATFPYLMLVVLLIRGVTLPGAAQGIQFYL--YPNLTRLWDPQVWMDAGTQIFFSFAIC 293
Query: 327 WGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKS 386
G L AL SYNK+ NNC+ D I +C N TS AGFAIFSILG M+ G +S+V +S
Sbjct: 294 LGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAES 353
Query: 387 GFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK- 445
G LAFIAYP A+ LP P W+ FFFM++ LGLDSQF +E++ T + D++P V +K
Sbjct: 354 GPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKK 413
Query: 446 -MRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGG 503
R + LG +V FL+GL+ +T+ G+Y L D++ A G +L AI E + + W+YG
Sbjct: 414 NRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGA 473
Query: 504 NRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYG-AIPYPDWG 562
RF ++ E MIG + W + CW +TP + A F++SL+++ Y YP WG
Sbjct: 474 KRFYDNIEDMIGYRPWPL---IKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWG 530
Query: 563 VALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASN 605
ALGW + + ++ IP ++ ++ KG +R+ PA +
Sbjct: 531 DALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAED 573
>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
GABA), member 11 [Homo sapiens]
Length = 632
Score = 461 bits (1187), Expect = e-130
Identities = 236/577 (40%), Positives = 348/577 (60%), Gaps = 38/577 (6%)
Query: 35 DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94
+RG+W+ K +++LS+ G +GLGNVWRFPYL Y NGGGAFLIPY + G+P+FFLE
Sbjct: 49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
Query: 95 SLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPW 153
+LGQF S G ++ WR + PLF+G+G +I + +YY +I+A++++Y+ F +ELPW
Sbjct: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
Query: 154 KNCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQL 212
C W+ +NC Q++ N S V + N T
Sbjct: 169 ATCGHEWNTENCVE---------------FQKLNVSNYSHVSLQNATS------------ 201
Query: 213 PSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFP 272
P ++W L S G+ G + W LALCLL AW I ++KG KS+GKVVY TA FP
Sbjct: 202 PVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFP 261
Query: 273 YVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVA 332
Y++LLILL+RG TL GAS+GI +Y+ + ++L + +VW DA TQIF+S ++ G L A
Sbjct: 262 YIMLLILLIRGVTLPGASEGIKFYL--YPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTA 319
Query: 333 LSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAF 392
L SYN + NNC+ D I++C N TS AGFAIFS+LG MA+ G +++V +SG LAF
Sbjct: 320 LGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAF 379
Query: 393 IAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK--MRVPI 450
IAYP+A+ +P P W+ LFF ML+ LGLDSQF +E++ T + D++PKV ++ R +
Sbjct: 380 IAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELL 439
Query: 451 TLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIED 509
L ++ + LGLV +T+ G+Y L D + A G +L AI E + I W+YG NRF ++
Sbjct: 440 ILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDN 499
Query: 510 TEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAI-PYPDWGVALGWC 568
E MIG + W CW ++TP + IFI+ L+++ Y I YP WG +GW
Sbjct: 500 IEDMIGYRPPSLIKW---CWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWL 556
Query: 569 MIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASN 605
M + ++ IP+ I + + +G + ++L P+++
Sbjct: 557 MALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTD 593
>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
sapiens]
Length = 635
Score = 456 bits (1174), Expect = e-128
Identities = 238/589 (40%), Positives = 353/589 (59%), Gaps = 39/589 (6%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
R W+++ D+++S +G+AVGLGNVWRFPYL Y NGGG FLIPY ++ + G+P+FFLE S
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 96 LGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKN 155
LGQF G ++VW I PLF+G+G ++I + YY +++A+ YY+ SF + LPW
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 156 CS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPS 214
C +W+ +C I H + + + + N TC ++ + P
Sbjct: 172 CGHTWNTPDCVE--IFRHEDCANAS---------------LANLTCDQLAD----RRSPV 210
Query: 215 EQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYV 274
++W L+ S G+ G + W + LCLL W++V ++KG+KS+GK+VYFTA FPYV
Sbjct: 211 IEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYV 270
Query: 275 VLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALS 334
VL++LLVRG L GA GI YY+ + +++KL +VW DA TQIF+S ++ G L AL
Sbjct: 271 VLVVLLVRGVLLPGALDGIIYYL--KPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALG 328
Query: 335 SYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIA 394
SYN+F NNC+ DAI++ L N TS FAGF +FSILG MA G +S+V +SG LAFIA
Sbjct: 329 SYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIA 388
Query: 395 YPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFP-----KVMKKMRVP 449
YP A+ +P P W+ LFFFMLL LGLDSQF +E T + DL P + +++ V
Sbjct: 389 YPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVA 448
Query: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIE 508
+ CC + F++ L VT G+Y L D++ A G +L A E V + W+YG +RF++
Sbjct: 449 L---CCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMD 505
Query: 509 DTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNY-GAIPYPDWGVALGW 567
D MIG R W+ W CW TP++ + IFI+++V + Y YP WG A+GW
Sbjct: 506 DIACMIG-YRPCPWMKW--CWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 562
Query: 568 CMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGE 616
+ ++ +P+ + +++AKG + +R +P WG + ++R +
Sbjct: 563 AFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPI--WGLHHLEYRAQ 609
>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 456 bits (1172), Expect = e-128
Identities = 244/570 (42%), Positives = 349/570 (61%), Gaps = 43/570 (7%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
R WS K D++LS+ G VGLGNVWRFPYL Y NGGGAFLIPY I L +GLP+FFLE
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 96 LGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154
+GQ+ S G ++ W +I PLF G+G V+I + +YY VI+A++ YY+F SFQ ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 155 NCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKS-WVDIN--NFTCINGSEIYQPG 210
+C+ SW+ +C +++ ++ NKS W+ I+ NFT
Sbjct: 161 HCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFTS---------- 193
Query: 211 QLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTAL 270
P ++W + L S G++ G + W LALCLLL WL+ ++KG++S+GKVVYFTA
Sbjct: 194 --PVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTAT 251
Query: 271 FPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGL 330
FP+ +LL+LLVRG TL GA GI +Y+ + T+L++ +VW DA TQIF+S ++ G +
Sbjct: 252 FPFAMLLVLLVRGLTLPGAGAGIKFYL--YPDITRLEDPQVWIDAGTQIFFSYAICLGAM 309
Query: 331 VALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDL 390
+L SYNK+K N + D +++ N TS +GFAIFSILG MA G +++ V +SG L
Sbjct: 310 TSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGL 369
Query: 391 AFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK--MRV 448
AFIAYP+A+ +P FWSILFF MLL LGLDSQF +E T++ DL+P ++K R
Sbjct: 370 AFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRRE 429
Query: 449 PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFI 507
C + +LLGL VT+ G+Y L D++ A G +L A E I WIYGG+
Sbjct: 430 IFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLY 489
Query: 508 EDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYG-AIPYPDWGVALG 566
+ E MIG + W + W VITP+L + FI+SLV++ Y YP+W + LG
Sbjct: 490 DGIEDMIGYRP---GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLG 546
Query: 567 WCMIVFCIIWIPIMAIIKIIQAKGNIFQRL 596
W + + ++ +P++ +I++ Q +G R+
Sbjct: 547 WSLALSSMLCVPLVIVIRLCQTEGPFLVRV 576
>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 456 bits (1172), Expect = e-128
Identities = 244/570 (42%), Positives = 349/570 (61%), Gaps = 43/570 (7%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
R WS K D++LS+ G VGLGNVWRFPYL Y NGGGAFLIPY I L +GLP+FFLE
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 96 LGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154
+GQ+ S G ++ W +I PLF G+G V+I + +YY VI+A++ YY+F SFQ ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 155 NCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKS-WVDIN--NFTCINGSEIYQPG 210
+C+ SW+ +C +++ ++ NKS W+ I+ NFT
Sbjct: 161 HCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFTS---------- 193
Query: 211 QLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTAL 270
P ++W + L S G++ G + W LALCLLL WL+ ++KG++S+GKVVYFTA
Sbjct: 194 --PVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTAT 251
Query: 271 FPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGL 330
FP+ +LL+LLVRG TL GA GI +Y+ + T+L++ +VW DA TQIF+S ++ G +
Sbjct: 252 FPFAMLLVLLVRGLTLPGAGAGIKFYL--YPDITRLEDPQVWIDAGTQIFFSYAICLGAM 309
Query: 331 VALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDL 390
+L SYNK+K N + D +++ N TS +GFAIFSILG MA G +++ V +SG L
Sbjct: 310 TSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGL 369
Query: 391 AFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK--MRV 448
AFIAYP+A+ +P FWSILFF MLL LGLDSQF +E T++ DL+P ++K R
Sbjct: 370 AFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRRE 429
Query: 449 PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFI 507
C + +LLGL VT+ G+Y L D++ A G +L A E I WIYGG+
Sbjct: 430 IFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLY 489
Query: 508 EDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYG-AIPYPDWGVALG 566
+ E MIG + W + W VITP+L + FI+SLV++ Y YP+W + LG
Sbjct: 490 DGIEDMIGYRP---GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLG 546
Query: 567 WCMIVFCIIWIPIMAIIKIIQAKGNIFQRL 596
W + + ++ +P++ +I++ Q +G R+
Sbjct: 547 WSLALSSMLCVPLVIVIRLCQTEGPFLVRV 576
>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
Length = 630
Score = 454 bits (1167), Expect = e-127
Identities = 237/577 (41%), Positives = 348/577 (60%), Gaps = 49/577 (8%)
Query: 35 DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94
+R W KK D+LLS+IGYAV LGNVWRFPY+ Y NGGGAFL+PY IM G+PLF++E
Sbjct: 78 ERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMEL 137
Query: 95 SLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPW 153
+LGQ+ G +S+WR I P+F+G+G + +I+ ++ YYN I+A++LYY+ +SF +LPW
Sbjct: 138 ALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPW 197
Query: 154 KNC-SSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQL 212
+C +SW+ NC+ ++ +N T S
Sbjct: 198 TSCKNSWNTGNCT-------------------------NYFSEDNITWTLHSTS------ 226
Query: 213 PSEQYWNKVALQ--RSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTAL 270
P+E+++ + LQ RS G+ + G I W LALC++L + ++ +++KG+K+SGKVV+ TA
Sbjct: 227 PAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTAT 286
Query: 271 FPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGL 330
FPY++L +LLVRGATL GA +G+ +Y+ + N+ KL E VW DAA QIF+SL +G L
Sbjct: 287 FPYIILSVLLVRGATLPGAWRGVLFYL--KPNWQKLLETGVWIDAAAQIFFSLGPGFGVL 344
Query: 331 VALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVK-SGFD 389
+A +SYNKF NNC+ DA+V + NC+TS +GF IF++LG+MA + ++VS+V K +G
Sbjct: 345 LAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPS 404
Query: 390 LAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVP 449
L FI Y EA+A +P F++I+FF ML+TLGLDS FA +E + T + D FP V K R
Sbjct: 405 LLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRER 464
Query: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIED 509
L + F LV +T G Y V L++ + G +L A++E V + W YG +F D
Sbjct: 465 FVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRD 524
Query: 510 TEMMIG-AKRWIFWLWWRACWFVITPILLIAI---FIWSLVQFHRPNYGAIPYPDWGVAL 565
+ M+G + W +WR CW I+P+ L+ I F+ S Q Y YP W + L
Sbjct: 525 VKEMLGFSPGW----FWRICWVAISPLFLLFIICSFLMSPPQLRLFQYN---YPYWSIIL 577
Query: 566 GWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRP 602
G+C+ I IP ++I G +R+I P
Sbjct: 578 GYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITP 614
>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
sapiens]
Length = 625
Score = 440 bits (1131), Expect = e-123
Identities = 233/589 (39%), Positives = 346/589 (58%), Gaps = 49/589 (8%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
R W+++ D+++S +G+AVGLGNVWRFPYL Y NGGG FLIPY ++ + G+P+FFLE S
Sbjct: 52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEIS 111
Query: 96 LGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKN 155
LGQF G ++VW I PLF+G+G ++I + YY +++A+ YY+ SF + LPW
Sbjct: 112 LGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWAT 171
Query: 156 CS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPS 214
C +W+ +C I H + + + + N TC + + P
Sbjct: 172 CGHTWNTPDCVE--IFRHEDCANAS---------------LANLTC----DQLADRRSPV 210
Query: 215 EQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYV 274
++W L+ S G+ G + W + LCLL W++V ++KG+KS+GK+VYFTA FPYV
Sbjct: 211 IEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYV 270
Query: 275 VLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALS 334
VL++LLVRG L GA GI YY+ + +++KL +VW DA TQIF+S ++ G L AL
Sbjct: 271 VLVVLLVRGVLLPGALDGIIYYL--KPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALG 328
Query: 335 SYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIA 394
SYN+F NNC++ TS FAGF +FSILG MA G +S+V +SG LAFIA
Sbjct: 329 SYNRFNNNCYNG----------TSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIA 378
Query: 395 YPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFP-----KVMKKMRVP 449
YP A+ +P P W+ LFFFMLL LGLDSQF +E T + DL P + +++ V
Sbjct: 379 YPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVA 438
Query: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIE 508
+ CC + F++ L VT G+Y L D++ A G +L A E V + W+YG +RF++
Sbjct: 439 L---CCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMD 495
Query: 509 DTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNY-GAIPYPDWGVALGW 567
D MIG R W+ W CW TP++ + IFI+++V + Y YP WG A+GW
Sbjct: 496 DIACMIG-YRPCPWMKW--CWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 552
Query: 568 CMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGE 616
+ ++ +P+ + +++AKG + +R +P WG + ++R +
Sbjct: 553 AFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPI--WGLHHLEYRAQ 599
>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
Length = 727
Score = 374 bits (959), Expect = e-103
Identities = 216/635 (34%), Positives = 336/635 (52%), Gaps = 123/635 (19%)
Query: 27 VGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAG 86
V E + +DR W+ K Y+L+ IG++VGLGN+WRFPYL NGGGA+L+PY ++L + G
Sbjct: 51 VEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIG 110
Query: 87 LPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFA 145
+PLFFLE ++GQ G + VW I P G+G + ++ +FV +YYNVII +S++Y F
Sbjct: 111 IPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFK 170
Query: 146 SFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSE 205
SFQ LPW C P+V + +V+ V ++
Sbjct: 171 SFQYPLPWSEC-----------PVVRNGSVAVVEAECEK--------------------- 198
Query: 206 IYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVV 265
+ +W + AL S ++E+G + W + LCLL+AW IVG A+ KGI+SSGKV+
Sbjct: 199 -----SSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVM 253
Query: 266 YFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSV 325
YF++LFPYVVL LVRG L GA GI + + + K+ + +VW++AATQ+F++L +
Sbjct: 254 YFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLD--KMLDPQVWREAATQVFFALGL 311
Query: 326 AWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFS------------------ 367
+GG++A SSYNK NNC DA +V N TSV A +F+
Sbjct: 312 GFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENA 371
Query: 368 --ILGHM----------------AHISGKEVSQVVK------------------------ 385
ILG++ +H++ K+ ++
Sbjct: 372 EKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDEL 431
Query: 386 ----SGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPK 441
G LAFIA+ EA+ P PFWS++FF ML+ LGL S ++ ITT I D F K
Sbjct: 432 DKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF-K 490
Query: 442 VMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIY 501
V K+M T+GCC+ FL+GL+ V ++G Y+V + D + A + + ILE + + WIY
Sbjct: 491 VPKEM---FTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIY 547
Query: 502 GGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQF--HRPNYGA---- 555
G +F+++ M+G + + F+ + W ++P+ + + S++Q P Y A
Sbjct: 548 GTKKFMQELTEMLGFRPYRFYFY---MWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKE 604
Query: 556 ------IPYPDWGVALGWCMIVFCIIWIPIMAIIK 584
+ +P+W +AL +IV + IP++ +++
Sbjct: 605 EAAERYLYFPNWAMALLITLIVVATLPIPVVFVLR 639
>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
Length = 628
Score = 373 bits (957), Expect = e-103
Identities = 213/623 (34%), Positives = 320/623 (51%), Gaps = 111/623 (17%)
Query: 31 DENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLF 90
D +R W K+ YLLS G+AVGLGN+WRFPYL + GGGAFLIPY I L G+P+F
Sbjct: 13 DLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIF 72
Query: 91 FLECSLGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQS 149
+E ++GQ G V VW I P GVG+ V +S +++YYN I+A+ L+Y+ SFQ
Sbjct: 73 HVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQH 132
Query: 150 ELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQP 209
LPW +C + +R+ V C
Sbjct: 133 PLPWSSC----PPDLNRTGFVEECQ----------------------------------- 153
Query: 210 GQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTA 269
G +W + L ++ +N++G I W+L +CL +W +V + +GI+++GKV+YFTA
Sbjct: 154 GSSAVSYFWYRQTLNITADINDSGSIQWWLLICLAASWAVVYMCVIRGIETTGKVIYFTA 213
Query: 270 LFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGG 329
LFPY+VL I L+RG TL GA+KG+ Y N L+ VW DAATQIF+SLS+A+GG
Sbjct: 214 LFPYLVLTIFLIRGLTLPGATKGLIYLF--TPNMHILQNPRVWLDAATQIFFSLSLAFGG 271
Query: 330 LVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMA---------------- 373
+A +SYN +N+C DA+V+ L N +TS++A A+FS+LG A
Sbjct: 272 HIAFASYNSPRNDCQKDAVVIALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLI 331
Query: 374 --------------------HISG---KEVSQV-------------VKSGFDLAFIAYPE 397
H++ K V+Q+ SG LAF+ + E
Sbjct: 332 NDFDFPEQSISRDDYPAVLMHLNATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTE 391
Query: 398 ALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLV 457
+PG P W++LFF ML TLGL + F ++E + T + D+ + +T CLV
Sbjct: 392 TDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVEAVITPLLDVGVLPRWVPKEALTGLVCLV 451
Query: 458 LFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAK 517
FL Q+G YW+ + D+F A +L+ A LE+VG++++YG RF +D M G +
Sbjct: 452 CFLSATCFTLQSGNYWLEIFDNFAASPNLLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRR 511
Query: 518 RWIFWLWWRACWFVITPILL------IAIFIWSLVQFH--RPNYGAIP------YPDWGV 563
+ WR W V++P+LL I + W +++ P Y P YP W
Sbjct: 512 PSPY---WRLTWRVVSPLLLTIFVAYIILLFWKPLRYKAWNPKYELFPSRQEKLYPGWAR 568
Query: 564 ALGWCMIVFCIIWIPIMAIIKII 586
A + + ++W+P+ A+ +++
Sbjct: 569 AACVLLSLLPVLWVPVAALAQLL 591
>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
sapiens]
Length = 520
Score = 364 bits (935), Expect = e-100
Identities = 199/522 (38%), Positives = 301/522 (57%), Gaps = 39/522 (7%)
Query: 103 GPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCS-SWSD 161
G ++VW I PLF+G+G ++I + YY +++A+ YY+ SF + LPW C +W+
Sbjct: 4 GSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNT 63
Query: 162 KNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKV 221
+C I H + + + + N TC ++ + P ++W
Sbjct: 64 PDCVE--IFRHEDCANAS---------------LANLTCDQLAD----RRSPVIEFWENK 102
Query: 222 ALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLV 281
L+ S G+ G + W + LCLL W++V ++KG+KS+GK+VYFTA FPYVVL++LLV
Sbjct: 103 VLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLV 162
Query: 282 RGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKN 341
RG L GA GI YY+ + +++KL +VW DA TQIF+S ++ G L AL SYN+F N
Sbjct: 163 RGVLLPGALDGIIYYL--KPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNN 220
Query: 342 NCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQ 401
NC+ DAI++ L N TS FAGF +FSILG MA G +S+V +SG LAFIAYP A+
Sbjct: 221 NCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTL 280
Query: 402 LPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFP-----KVMKKMRVPITLGCCL 456
+P P W+ LFFFMLL LGLDSQF +E T + DL P + +++ V + CC
Sbjct: 281 MPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVAL---CCA 337
Query: 457 VLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIEDTEMMIG 515
+ F++ L VT G+Y L D++ A G +L A E V + W+YG +RF++D MIG
Sbjct: 338 LCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIG 397
Query: 516 AKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNY-GAIPYPDWGVALGWCMIVFCI 574
R W+ W CW TP++ + IFI+++V + Y YP WG A+GW + +
Sbjct: 398 -YRPCPWMKW--CWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSM 454
Query: 575 IWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGE 616
+ +P+ + +++AKG + +R +P WG + ++R +
Sbjct: 455 LCVPLHLLGCLLRAKGTMAERWQHLTQPI--WGLHHLEYRAQ 494
>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
Length = 634
Score = 355 bits (910), Expect = 9e-98
Identities = 211/647 (32%), Positives = 323/647 (49%), Gaps = 115/647 (17%)
Query: 29 ENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLP 88
E +E R W K+ Y+L+ +G+ VGLGNVWRFPYL S+GGGAF+IP+ I+L L G+P
Sbjct: 25 EQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIP 84
Query: 89 LFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASF 147
L +LE ++GQ G + VW I P +G+G+ +L S V +YYN II++ ++Y+F SF
Sbjct: 85 LLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSF 144
Query: 148 QSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIY 207
Q LPW +C N +++ V C S+
Sbjct: 145 QEPLPWSDCPL----NENQTGYVDECARSS------------------------------ 170
Query: 208 QPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYF 267
P + +W + L S+ ++++G I W++ LCL AW ++ +GI+++GK VY
Sbjct: 171 -----PVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYI 225
Query: 268 TALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAW 327
T+ PYVVL I L+RG TL+GA+ GI + N T+L + + W DA Q+F+S S+A+
Sbjct: 226 TSTLPYVVLTIFLIRGLTLKGATNGIVFLF--TPNVTELAQPDTWLDAGAQVFFSFSLAF 283
Query: 328 GGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQ----V 383
GGL++ SSYN NNC D+++V + N TSV+ ++S++G A +
Sbjct: 284 GGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILT 343
Query: 384 VKSGFDL------------------------------------------------AFIAY 395
+ +GFDL AFI +
Sbjct: 344 LINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVF 403
Query: 396 PEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCC 455
EA+ ++P P WS+LFF ML LGL S F ++E + +QDL K + +T C
Sbjct: 404 TEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLIC 463
Query: 456 LVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIG 515
L FL+G + +G YW+ L+D + +LI A E+ ++++YG +RF +D E MIG
Sbjct: 464 LGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIG 523
Query: 516 AKRWIFWLWWRACWFVITPILLIAIFIWSLV---------QFHRPNYGAIP------YPD 560
K IF W+ W V++P+L++ IF++ V P Y P YP+
Sbjct: 524 HKPNIF---WQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPN 580
Query: 561 WGVALGWCMIVFCIIWIPIMAIIKIIQ---AKGNIFQRLISCCRPAS 604
W + + + IP AI K+I+ K Q L+S AS
Sbjct: 581 WVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTAS 627
>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
sapiens]
Length = 592
Score = 326 bits (836), Expect = 4e-89
Identities = 193/583 (33%), Positives = 290/583 (49%), Gaps = 101/583 (17%)
Query: 39 WSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQ 98
W+ ++ + I YAVGLGNVWRFPYL GGG+FL+PY IML + G+PL +LE ++GQ
Sbjct: 8 WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67
Query: 99 FASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCS 157
G + WR I P GVG+ V++S F+++YYNVI A++ +Y+F SFQ LPW
Sbjct: 68 RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPW---- 123
Query: 158 SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQY 217
+ C ++ + G E + S ++ +
Sbjct: 124 -------------SVCPLNGNHTGYDEECEKASS----------------------TQYF 148
Query: 218 WNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLL 277
W + L S + E G + W ALCLLLAWL+V + +G +S+GKVVYFTA PY VL+
Sbjct: 149 WYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLI 208
Query: 278 ILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYN 337
I L+RG TL GA+ G+ Y +L + W +AATQIF+SL + +G L+A +SYN
Sbjct: 209 IYLIRGLTLHGATNGLMYMF--TPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYN 266
Query: 338 KFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISG----KEVSQVVKSGFD---- 389
+ NNC AI+V L N TS+FA FSI G A + K+VS ++ + FD
Sbjct: 267 EPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDG 326
Query: 390 ----------------------------------------------LAFIAYPEALAQLP 403
LAFI Y EA+ +
Sbjct: 327 FLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNME 386
Query: 404 GGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGL 463
WS+L+FFMLL LG+ S + I T + D + I+ CLV +G+
Sbjct: 387 VSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGM 446
Query: 464 VCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWL 523
V +AG YW + + + A +L+ ++E + + ++YG RF D + M G R + W
Sbjct: 447 VFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTG--RAVSW- 503
Query: 524 WWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
+W+ W ++P+L++++F++ L + G + Y W + G
Sbjct: 504 YWKVMWAGVSPLLIVSLFVFYLSDYILT--GTLKYQAWDASQG 544
>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
sapiens]
Length = 555
Score = 274 bits (700), Expect = 2e-73
Identities = 173/583 (29%), Positives = 267/583 (45%), Gaps = 138/583 (23%)
Query: 39 WSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQ 98
W+ ++ + I YAVGLGNVWRFPYL GGG+FL+PY IML + G+PL +LE ++GQ
Sbjct: 8 WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67
Query: 99 FASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCS 157
G + WR I P GVG+ V++S F+++YYNVI A++ +Y+F SFQ LPW
Sbjct: 68 RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPW---- 123
Query: 158 SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQY 217
+ C ++ + G E + S ++ +
Sbjct: 124 -------------SVCPLNGNHTGYDEECEKASS----------------------TQYF 148
Query: 218 WNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLL 277
W + L S + E G + W ALCLLLAWL+V + +G +S+GK+
Sbjct: 149 WYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKI------------- 195
Query: 278 ILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYN 337
+L + W +AATQIF+SL + +G L+A +SYN
Sbjct: 196 --------------------------EQLANPKAWINAATQIFFSLGLGFGSLIAFASYN 229
Query: 338 KFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISG----KEVSQVVKSGFD---- 389
+ NNC AI+V L N TS+FA FSI G A + K+VS ++ + FD
Sbjct: 230 EPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDG 289
Query: 390 ----------------------------------------------LAFIAYPEALAQLP 403
LAFI Y EA+ +
Sbjct: 290 FLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNME 349
Query: 404 GGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGL 463
WS+L+FFMLL LG+ S + I T + D + I+ CLV +G+
Sbjct: 350 VSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGM 409
Query: 464 VCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWL 523
V +AG YW + + + A +L+ ++E + + ++YG RF D + M G R + W
Sbjct: 410 VFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTG--RAVSW- 466
Query: 524 WWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG 566
+W+ W ++P+L++++F++ L + G + Y W + G
Sbjct: 467 YWKVMWAGVSPLLIVSLFVFYLSDYILT--GTLKYQAWDASQG 507
>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
sapiens]
Length = 730
Score = 273 bits (698), Expect = 4e-73
Identities = 145/368 (39%), Positives = 209/368 (56%), Gaps = 41/368 (11%)
Query: 10 FKCREKEKVSASSENFHVGENDENQD-RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYS 68
FK E ++ V E E +D R W+ K Y+L+ +G++VGLGNVWRFPYL
Sbjct: 34 FKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQK 93
Query: 69 NGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIF 127
NGGGA+L+PY I+L + G+PLFFLE S+GQ G + VW I P G+G ++ F
Sbjct: 94 NGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYF 153
Query: 128 VTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQ 187
V +YYNVII +SL+Y SFQ LPW C KN S + + C S+
Sbjct: 154 VALYYNVIIGWSLFYFSQSFQQPLPWDQCPLV--KNASHTFVEPECEQSSA--------- 202
Query: 188 MNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAW 247
+ YW + AL SS ++E+G + W + +CLL AW
Sbjct: 203 --------------------------TTYYWYREALNISSSISESGGLNWKMTICLLAAW 236
Query: 248 LIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLK 307
++V A+ KGI+SSGK++YF++LFPYVVL+ L+R L G+ GI + + +
Sbjct: 237 VMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEI--ML 294
Query: 308 EAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFS 367
E +VW++AATQ+F++L + +GG++A SSYNK NNC DA++V N TSV A +F+
Sbjct: 295 EPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFA 354
Query: 368 ILGHMAHI 375
+LG A++
Sbjct: 355 VLGFKANV 362
>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
Length = 736
Score = 242 bits (618), Expect = 7e-64
Identities = 167/626 (26%), Positives = 274/626 (43%), Gaps = 138/626 (22%)
Query: 39 WSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQ 98
WS K++Y+L+ +G+++ +WRF YL ++GG +F Y ML L G+PL FLE + GQ
Sbjct: 106 WSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMAAGQ 165
Query: 99 FASLGPVSVWRIL-PLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNC- 156
G + VW+I+ P GVG + ++ + +Y+NV+ ++ ++YM SFQ +PW+ C
Sbjct: 166 SMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWEKCP 225
Query: 157 ----SSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQL 212
SS D C R+
Sbjct: 226 LTMNSSGFDPECERT--------------------------------------------T 241
Query: 213 PSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFP 272
PS +W + AL+ S + + G V+ L L L W +VGA + G+KS+GKV+Y L P
Sbjct: 242 PSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLP 301
Query: 273 YVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVA 332
+++ +R LEGA G+ + A+ + + VW A Q+ + + G + +
Sbjct: 302 CFIIVGFFIRTLLLEGAKFGLQQLVVAK--ISDVYNMSVWSLAGGQVLSNTGIGLGSVAS 359
Query: 333 LSSYNKFKNNCFSDAIVVCLTNCLT-SVFAGFAIFSILGHMA------------------ 373
L+SY NNC SDA +V + N LT VF F F +LG A
Sbjct: 360 LASYMPQSNNCLSDAFLVSVINLLTLLVFTSFN-FCVLGFWATVITHRCCERNAEILLKL 418
Query: 374 ---------------------------------HISGKEVSQVVKSGFDLAF-------- 392
HI + +V + + F
Sbjct: 419 INLGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPK 478
Query: 393 ---IAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVP 449
+++ EA++ LP FWS +FF MLL +GL S ++ I T +QD F K ++
Sbjct: 479 FAFLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKL- 537
Query: 450 ITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIED 509
+ +G L++F+ GL +G Y++ L+ + + I++ + E + + W YG RF+ D
Sbjct: 538 LIVGVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLAD 597
Query: 510 TEMMIG--AKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAI----------- 556
+++G WLW C P++L+ IF+ +V +
Sbjct: 598 LTILLGHPISPIFGWLWPHLC-----PVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVL 652
Query: 557 -PYPDWGVALGWCMIVFCIIWIPIMA 581
PYP W + L + +F I+ +PI A
Sbjct: 653 RPYPPWALLL--MITLFAIVILPIPA 676
>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
sapiens]
Length = 623
Score = 205 bits (521), Expect = 1e-52
Identities = 110/291 (37%), Positives = 161/291 (55%), Gaps = 40/291 (13%)
Query: 86 GLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMF 144
G+PLFFLE S+GQ G + VW I P G+G ++ FV +YYNVII +SL+Y
Sbjct: 4 GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63
Query: 145 ASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGS 204
SFQ LPW C KN S + + C S+
Sbjct: 64 QSFQQPLPWDQCPLV--KNASHTFVEPECEQSSA-------------------------- 95
Query: 205 EIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKV 264
+ YW + AL SS ++E+G + W + +CLL AW++V A+ KGI+SSGK+
Sbjct: 96 ---------TTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKI 146
Query: 265 VYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLS 324
+YF++LFPYVVL+ L+R L G+ GI + + + E +VW++AATQ+F++L
Sbjct: 147 IYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEI--MLEPKVWREAATQVFFALG 204
Query: 325 VAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHI 375
+ +GG++A SSYNK NNC DA++V N TSV A +F++LG A++
Sbjct: 205 LGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANV 255
>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
sapiens]
Length = 289
Score = 182 bits (463), Expect = 6e-46
Identities = 104/273 (38%), Positives = 146/273 (53%), Gaps = 42/273 (15%)
Query: 10 FKCREKEKVSASSENFHVGENDENQD-RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYS 68
FK E ++ V E E +D R W+ K Y+L+ +G++VGLGNVWRFPYL
Sbjct: 34 FKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQK 93
Query: 69 NGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWR-ILPLFQGVGITMVLISIF 127
NGGGA+L+PY I+L + G+PLFFLE S+GQ G + VW I P G+G ++ F
Sbjct: 94 NGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYF 153
Query: 128 VTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQ 187
V +YYNVII +SL+Y SFQ LPW C KN S + + C S+
Sbjct: 154 VALYYNVIIGWSLFYFSQSFQQPLPWDQCP--LVKNASHTFVEPECEQSSA--------- 202
Query: 188 MNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAW 247
+ YW + AL SS ++E+G + W + +CLL AW
Sbjct: 203 --------------------------TTYYWYREALNISSSISESGGLNWKMTICLLAAW 236
Query: 248 LIVGAALFKGIKSSGKVVYFTALFPYVVLLILL 280
++V A+ KGI+SSGKV + L P+++LLI +
Sbjct: 237 VMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266
>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform b [Homo sapiens]
Length = 200
Score = 154 bits (390), Expect = 2e-37
Identities = 80/169 (47%), Positives = 109/169 (64%), Gaps = 22/169 (13%)
Query: 36 RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95
R WS K D++LS+ G VGLGNVWRFPYL Y NGGGAFLIPY I L +GLP+FFLE
Sbjct: 41 REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
Query: 96 LGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154
+GQ+ S G ++ W +I PLF G+G V+I + +YY VI+A++ YY+F SFQ ELPW
Sbjct: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
Query: 155 NCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKS-WVDIN--NFT 199
+C+ SW+ +C +++ ++ NKS W+ I+ NFT
Sbjct: 161 HCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFT 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,271,218
Number of Sequences: 37866
Number of extensions: 1041969
Number of successful extensions: 3286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3094
Number of HSP's gapped (non-prelim): 56
length of query: 642
length of database: 18,247,518
effective HSP length: 109
effective length of query: 533
effective length of database: 14,120,124
effective search space: 7526026092
effective search space used: 7526026092
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.