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Search of human proteins with 5921465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5921465 claudin 10 isoform b [Homo sapiens]
(228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5921465 claudin 10 isoform b [Homo sapiens] 466 e-132
gi|33598916 claudin 10 isoform a [Homo sapiens] 346 8e-96
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 332 2e-91
gi|7656981 claudin 15 [Homo sapiens] 199 2e-51
gi|183979973 claudin 19 isoform a [Homo sapiens] 160 1e-39
gi|183979975 claudin 19 isoform b [Homo sapiens] 160 1e-39
gi|153792186 claudin 7 [Homo sapiens] 158 4e-39
gi|10863887 claudin 1 [Homo sapiens] 139 2e-33
gi|4502875 claudin 3 [Homo sapiens] 139 2e-33
gi|195947374 claudin 5 [Homo sapiens] 137 8e-33
gi|195947372 claudin 5 [Homo sapiens] 137 8e-33
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 135 4e-32
gi|40788011 claudin 8 [Homo sapiens] 133 1e-31
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 133 1e-31
gi|4502877 claudin 4 [Homo sapiens] 132 2e-31
gi|153792768 claudin 6 [Homo sapiens] 131 4e-31
gi|11141861 claudin 9 [Homo sapiens] 129 2e-30
gi|225703142 claudin 14 [Homo sapiens] 127 6e-30
gi|21536294 claudin 14 [Homo sapiens] 127 6e-30
gi|225703138 claudin 14 [Homo sapiens] 127 6e-30
gi|6912314 claudin 14 [Homo sapiens] 127 6e-30
gi|225703140 claudin 14 [Homo sapiens] 127 6e-30
gi|9966781 claudin 2 [Homo sapiens] 114 9e-26
gi|47716519 claudin 20 [Homo sapiens] 111 6e-25
gi|6912316 claudin 17 [Homo sapiens] 110 8e-25
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 100 1e-21
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 100 2e-21
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 100 2e-21
gi|162417973 claudin 22 [Homo sapiens] 99 4e-21
gi|10938016 claudin 11 [Homo sapiens] 94 1e-19
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 466 bits (1199), Expect = e-132
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV 60
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV
Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV 60
Query: 61 SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLA 120
SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLA
Sbjct: 61 SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLA 120
Query: 121 GIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC 180
GIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC
Sbjct: 121 GIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC 180
Query: 181 FSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
FSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV
Sbjct: 181 FSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 346 bits (888), Expect = 8e-96
Identities = 170/223 (76%), Positives = 189/223 (84%)
Query: 6 SEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKD 65
++I A + + G+ + + ++ WKV+T +VIT + LW C ++ G +C+
Sbjct: 4 AQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCRP 63
Query: 66 FPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 125
++ + GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI
Sbjct: 64 HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123
Query: 126 LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD 185
LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD 183
Query: 186 NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV
Sbjct: 184 NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 226
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 332 bits (851), Expect = 2e-91
Identities = 168/223 (75%), Positives = 180/223 (80%), Gaps = 19/223 (8%)
Query: 6 SEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKD 65
++I A + + G+ + + ++ WKV+T +VIT + LW C
Sbjct: 4 AQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCA----------- 52
Query: 66 FPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 125
GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI
Sbjct: 53 --------GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104
Query: 126 LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD 185
LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISD 164
Query: 186 NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV
Sbjct: 165 NNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 207
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 199 bits (505), Expect = 2e-51
Identities = 104/232 (44%), Positives = 140/232 (60%), Gaps = 11/232 (4%)
Query: 3 STASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSN 62
S A E F ++ G +++ TLP YW+VST+ G VITT T + NLW +C TDS GV N
Sbjct: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYN 61
Query: 63 CKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSD-KAKAKIACLAG 121
C +FPSMLAL GYIQACR LMI A+ LGF G + + G++CT +GG + KAK+A AG
Sbjct: 62 CWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAG 121
Query: 122 IVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCF 181
+ IL+G+C M S YA IT +FFDPL+ KYELG AL++GW+ + + I+GG+ C
Sbjct: 122 ALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCS 181
Query: 182 -----SISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
S D + R Y SVM T G+ + ++ +NAYV
Sbjct: 182 ACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGD-----SSFGKYGRNAYV 228
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 160 bits (404), Expect = 1e-39
Identities = 78/183 (42%), Positives = 116/183 (63%), Gaps = 3/183 (1%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTAT-YWANLWKACVTDSTG 59
MA++ +++ + +++ GWV + ++ WK S+ G I TA + LW +C + STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIAC 118
CK + S+LALDG+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
G +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 178 IFC 180
C
Sbjct: 181 FLC 183
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 160 bits (404), Expect = 1e-39
Identities = 78/183 (42%), Positives = 116/183 (63%), Gaps = 3/183 (1%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTAT-YWANLWKACVTDSTG 59
MA++ +++ + +++ GWV + ++ WK S+ G I TA + LW +C + STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIAC 118
CK + S+LALDG+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
G +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 178 IFC 180
C
Sbjct: 181 FLC 183
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 158 bits (399), Expect = 4e-39
Identities = 79/195 (40%), Positives = 119/195 (61%), Gaps = 3/195 (1%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDG-TVITTATYWANLWKACVTDSTG 59
MA++ +++ F +++ GWV + + W++S+ G +IT + LW CVT STG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIAC 118
+ +CK + S+LAL +QA R LM+ ++ LGF A GMKCT+ GG DK KA+IA
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
GI+FI++GL ++ CS Y ++I T+F++PL KYE G A+FIGWAG++L I+GG
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 178 IFCFSISDNNKTPRY 192
+ S N Y
Sbjct: 181 LLSCSCPGNESKAGY 195
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 139 bits (351), Expect = 2e-33
Identities = 71/187 (37%), Positives = 109/187 (58%), Gaps = 7/187 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDG-TVITTATYWANLWKACVTDS 57
MA+ +++ F+++ GW+ +VS+ LP W++ + G ++T + LW +CV+ S
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQ--WRIYSYAGDNIVTAQAMYEGLWMSCVSQS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKI 116
TG CK F S+L L +QA R LM+ + LG A GMKC K D+ K ++
Sbjct: 59 TGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRM 118
Query: 117 ACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIG 175
A + G +F+L+GL + + Y N+I EF+DP+ V +YE G ALF GWA ASLC++G
Sbjct: 119 AVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLG 178
Query: 176 GVIFCFS 182
G + C S
Sbjct: 179 GALLCCS 185
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 139 bits (350), Expect = 2e-33
Identities = 82/211 (38%), Positives = 120/211 (56%), Gaps = 11/211 (5%)
Query: 3 STASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDSTG 59
S EI +++ GW+ +V LP W+VS G+ +IT+ W LW CV STG
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPM--WRVSAFIGSNIITSQNIWEGLWMNCVVQSTG 59
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACL 119
CK + S+LAL +QA R L++ A+ L FG + AL G +CT D AKAKI +
Sbjct: 60 QMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIV 119
Query: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVI 178
AG++F+L+ L ++ S AN I +F++P+ E QK E+GA L++GWA A+L ++GG +
Sbjct: 120 AGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGAL 179
Query: 179 FCFSISDNNKTPRYTYNGATSVMSSRTKYHG 209
C S K +YT AT V+ S + G
Sbjct: 180 LCCSCPPREK--KYT---ATKVVYSAPRSTG 205
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 137 bits (345), Expect = 8e-33
Identities = 71/184 (38%), Positives = 108/184 (58%), Gaps = 6/184 (3%)
Query: 1 MASTASEIIAFMVSISGW--VLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57
M S A EI+ ++ + GW ++++ LP W+V+ +D ++T T W LW +CV S
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPM--WQVTAFLDHNIVTAQTTWKGLWMSCVVQS 143
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG CK + S+LAL +QA R L ++AV L F L G +CT AKA++A
Sbjct: 144 TGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVA 203
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGG 176
G++++ GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG
Sbjct: 204 LTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263
Query: 177 VIFC 180
+ C
Sbjct: 264 CLLC 267
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 137 bits (345), Expect = 8e-33
Identities = 71/184 (38%), Positives = 108/184 (58%), Gaps = 6/184 (3%)
Query: 1 MASTASEIIAFMVSISGW--VLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57
M S A EI+ ++ + GW ++++ LP W+V+ +D ++T T W LW +CV S
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPM--WQVTAFLDHNIVTAQTTWKGLWMSCVVQS 143
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG CK + S+LAL +QA R L ++AV L F L G +CT AKA++A
Sbjct: 144 TGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVA 203
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGG 176
G++++ GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG
Sbjct: 204 LTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263
Query: 177 VIFC 180
+ C
Sbjct: 264 CLLC 267
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 135 bits (339), Expect = 4e-32
Identities = 81/257 (31%), Positives = 129/257 (50%), Gaps = 37/257 (14%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV 60
M++T +++AF++SI G + D W + +T+ + LW++CV S+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60
Query: 61 SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGG-SDKAKAKIACL 119
+ C+ + ++L L +QA R LMI + LG G + ++F +KC ++G D AKA +
Sbjct: 61 TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
Query: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPL------------FVEQKYELGAALFIGWA 167
+GI+FI+SGLC++ G S++AN + T F+ V+ +Y GAALF+GW
Sbjct: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
Query: 168 GASLCIIGGVIFCFSI------SDNNKTPRYTYNG-----------ATSVMSSRTK---- 206
L +IGGV+ C + N K Y +G A++ S TK
Sbjct: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
Query: 207 YHGG---EDFKTTNPSK 220
Y GG ED + PSK
Sbjct: 241 YDGGARTEDEVQSYPSK 257
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 133 bits (335), Expect = 1e-31
Identities = 78/225 (34%), Positives = 118/225 (52%), Gaps = 4/225 (1%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDSTG 59
MA+ A EI + G V + W+VS I+ ++ +W LW CV +
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTK-VGGSDKAKAKIAC 118
CK + S+LAL +QA RGLM AA + F + A+ GMKCT+ G ++K KA I
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
AGI+FI++G+ + S AN I +F++ + V QK ELG AL++GW A + I+GG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 178 IFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQF 222
+FC N K+ Y Y+ S +++ YH G+ + Q+
Sbjct: 181 LFCCVFCCNEKSSSYRYS-IPSHRTTQKSYHTGKKSPSVYSRSQY 224
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 133 bits (335), Expect = 1e-31
Identities = 82/257 (31%), Positives = 128/257 (49%), Gaps = 37/257 (14%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV 60
MA TA + + F+VS+ G + + D W + +T + LW++CV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGF 60
Query: 61 SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGG-SDKAKAKIACL 119
+ C+ + ++L L +QA R LMI + LG G + ++F +KC ++G D AKA +
Sbjct: 61 TECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
Query: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPL------------FVEQKYELGAALFIGWA 167
+GI+FI+SGLC++ G S++AN + T F+ V+ +Y GAALF+GW
Sbjct: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
Query: 168 GASLCIIGGVIFCFSI------SDNNKTPRYTYNG-----------ATSVMSSRTK---- 206
L +IGGV+ C + N K Y +G A++ S TK
Sbjct: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
Query: 207 YHGG---EDFKTTNPSK 220
Y GG ED + PSK
Sbjct: 241 YDGGARTEDEVQSYPSK 257
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 132 bits (333), Expect = 2e-31
Identities = 70/206 (33%), Positives = 114/206 (55%), Gaps = 3/206 (1%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDSTG 59
MAS +++ +++ GW+ V W+V+ G+ ++T+ T W LW CV STG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACL 119
CK + S+LAL +QA R L+I ++ + G + ++ G KCT + AKAK +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVI 178
AG+VF+L+GL + S A+ I +F++PL QK E+GA+L++GWA + L ++GG +
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 179 FCFSISDNNKTP-RYTYNGATSVMSS 203
C + P Y+ A S +S
Sbjct: 181 LCCNCPPRTDKPYSAKYSAARSAAAS 206
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 131 bits (330), Expect = 4e-31
Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 6/184 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTA-TYWANLWKACVTDS 57
MAS +I+ ++++ GWV LVS LP WKV+ G I A W LW +CV S
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPM--WKVTAFIGNSIVVAQVVWEGLWMSCVVQS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG CK + S+LAL +QA R L + A+ + FG + L G KCT +KA++
Sbjct: 59 TGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLV 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
+GIVF++SG+ ++ A+ I +F++PL E QK ELGA+L++GWA + L ++GG
Sbjct: 119 LTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGG 178
Query: 177 VIFC 180
+ C
Sbjct: 179 GLLC 182
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 129 bits (324), Expect = 2e-30
Identities = 71/184 (38%), Positives = 106/184 (57%), Gaps = 6/184 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTA-TYWANLWKACVTDS 57
MAST E++ +++ GW+ LVS LP WKV+ G I A W LW +CV S
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPL--WKVTAFIGNSIVVAQVVWEGLWMSCVVQS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG CK + S+LAL +QA R L + A+ L G + A+ G +CT + AKA+I
Sbjct: 59 TGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIV 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ-KYELGAALFIGWAGASLCIIGG 176
AG++ +L+G+ + A+ I +F++PL E K ELGA+L++GWA A+L ++GG
Sbjct: 119 LTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGG 178
Query: 177 VIFC 180
+ C
Sbjct: 179 GLLC 182
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 127 bits (320), Expect = 6e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
Query: 177 VIFCFSISD 185
+ C S D
Sbjct: 179 TLLCLSCQD 187
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 127 bits (320), Expect = 6e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
Query: 177 VIFCFSISD 185
+ C S D
Sbjct: 179 TLLCLSCQD 187
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 127 bits (320), Expect = 6e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
Query: 177 VIFCFSISD 185
+ C S D
Sbjct: 179 TLLCLSCQD 187
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 127 bits (320), Expect = 6e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
Query: 177 VIFCFSISD 185
+ C S D
Sbjct: 179 TLLCLSCQD 187
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 127 bits (320), Expect = 6e-30
Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 6/189 (3%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDS 57
MASTA +++ F++S G V L+++ LP +W+ + GT ++T +Y LW CV S
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILP--HWRRTAHVGTNILTAVSYLKGLWMECVWHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ C+ + S+LAL +QA R LM+ + L A+ GMKCT+ AK A
Sbjct: 59 TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
L G +FIL+GL M S N + F++PL K+E+G AL++G+ +SL +IGG
Sbjct: 119 ILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGG 178
Query: 177 VIFCFSISD 185
+ C S D
Sbjct: 179 TLLCLSCQD 187
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 114 bits (284), Expect = 9e-26
Identities = 66/232 (28%), Positives = 116/232 (50%), Gaps = 6/232 (2%)
Query: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTATYWAN-LWKACVTDS 57
MAS +++ +++ + G + LV+ LP+ WK S+ G I TA ++ LW C T S
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPS--WKTSSYVGASIVTAVGFSKGLWMECATHS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG++ C + ++L L IQA + +M+ + ++ I ++ GM+CT +AK ++A
Sbjct: 59 TGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVA 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
G+ FIL GL + + I +F+ PL + K+E+G AL++G + +I G
Sbjct: 119 VAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAG 178
Query: 177 VIFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
+I CFS S Y +++R+ G+ K + + YV
Sbjct: 179 IILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 111 bits (277), Expect = 6e-25
Identities = 67/195 (34%), Positives = 103/195 (52%), Gaps = 6/195 (3%)
Query: 1 MASTASEIIAFMVSISG--WVLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57
MAS +++AF++++SG VL ++ LP WKV+ +D +IT LW C S
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPN--WKVNVDVDSNIITAIVQLHGLWMDCTWYS 58
Query: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
TG+ +C S+L+L ++QA R M+ A L G + GMKCT++GG + K+ +
Sbjct: 59 TGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHAS 118
Query: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
G+ F+ +G+ S+ Y +I F D E K+E G A++IG+ A L I G
Sbjct: 119 FAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISG 178
Query: 177 VIFCFSISDNNKTPR 191
+IFC S N R
Sbjct: 179 MIFCTSCIKRNPEAR 193
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 110 bits (276), Expect = 8e-25
Identities = 68/199 (34%), Positives = 103/199 (51%), Gaps = 7/199 (3%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDSTG 59
MA +I ++ G V +T W+VS G+ +I W LW C+ +
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMK---CTKVGGSDKAKAKI 116
CK + S+LAL ++ R LM AV+L + + GMK CT G +++AKA +
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCT--GSNERAKAYL 118
Query: 117 ACLAGIVFILSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIG 175
+G++FIL+G+ + S AN I +F++P + + QK ELGAALF+GWA A++ IG
Sbjct: 119 LGTSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIG 178
Query: 176 GVIFCFSISDNNKTPRYTY 194
G + C N K Y Y
Sbjct: 179 GGLLCGFCCCNRKKQGYRY 197
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 100 bits (249), Expect = 1e-21
Identities = 64/188 (34%), Positives = 99/188 (52%), Gaps = 8/188 (4%)
Query: 4 TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63
TA + + ++S+ GW+L T +WK +D + T LW+ CV C
Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122
KDF S LAL ++ R LM + LGF G + + FG+ C ++G S + K ++ L GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178
+ SG+ ++ S A+K EF+D P FV ++E G ALF+GW AG SL + G ++
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 179 FCFSISDN 186
C + S +
Sbjct: 184 NCAACSSH 191
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 99.8 bits (247), Expect = 2e-21
Identities = 64/188 (34%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Query: 4 TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63
TA + + ++S GW+L T +WK +D + T LW+ CV C
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122
KDF S LAL ++ R LM + LGF G + + FG+ C ++G S + K ++ L GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178
+ SG+ ++ S A+K EF+D P FV ++E G ALF+GW AG SL + G ++
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 179 FCFSISDN 186
C + S +
Sbjct: 184 NCAACSSH 191
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 99.8 bits (247), Expect = 2e-21
Identities = 64/188 (34%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Query: 4 TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63
TA + + ++S GW+L T +WK +D + T LW+ CV C
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122
KDF S LAL ++ R LM + LGF G + + FG+ C ++G S + K ++ L GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178
+ SG+ ++ S A+K EF+D P FV ++E G ALF+GW AG SL + G ++
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 179 FCFSISDN 186
C + S +
Sbjct: 184 NCAACSSH 191
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 98.6 bits (244), Expect = 4e-21
Identities = 64/188 (34%), Positives = 98/188 (52%), Gaps = 8/188 (4%)
Query: 4 TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63
T +++ +S+ GWVL T +WK +D + T LW+ CV C
Sbjct: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122
KDF S LAL ++ R LM + LGF G + + FG+ C ++G S + K ++ L GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178
+ SG+ ++ S A+K EF+D P FV ++E G ALF+GW AG SL + G ++
Sbjct: 125 LSWASGVTALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 179 FCFSISDN 186
C + S +
Sbjct: 184 HCAACSSH 191
>gi|10938016 claudin 11 [Homo sapiens]
Length = 207
Score = 93.6 bits (231), Expect = 1e-19
Identities = 66/190 (34%), Positives = 95/190 (50%), Gaps = 23/190 (12%)
Query: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYW-----ANLWKACVT 55
M +T +++ F+ S GW+ V T T+ W V+ G I T LW CV
Sbjct: 1 MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
Query: 56 DSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKA 114
+TG+ +CK +L L GY+QACR LMIAA LG + L + C ++G AK
Sbjct: 59 -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
Query: 115 KIACLAGIVFILSGLCSMTGCSLY---ANKITTEFFDPLFVEQKYELGAALFIGWAGASL 171
+ A LAG++ IL LC++ + A++ TT G +L+ GW GA L
Sbjct: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRETTIV----------SFGYSLYAGWIGAVL 167
Query: 172 CIIGG-VIFC 180
C++GG VI C
Sbjct: 168 CLVGGCVILC 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,806,383
Number of Sequences: 37866
Number of extensions: 297223
Number of successful extensions: 706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 595
Number of HSP's gapped (non-prelim): 54
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.