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Search of human proteins with 5803145
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5803145 ralA binding protein 1 [Homo sapiens]
(655 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5803145 ralA binding protein 1 [Homo sapiens] 1300 0.0
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 107 3e-23
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 107 3e-23
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 107 5e-23
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 107 5e-23
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 105 1e-22
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 105 2e-22
gi|229094128 active breakpoint cluster region-related protein i... 102 9e-22
gi|38679957 active breakpoint cluster region-related protein is... 102 9e-22
gi|38679954 active breakpoint cluster region-related protein is... 102 9e-22
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 97 5e-20
gi|156119615 myosin IXA [Homo sapiens] 96 1e-19
gi|188497642 ARHGAP15 [Homo sapiens] 94 3e-19
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 94 4e-19
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 92 2e-18
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 91 3e-18
gi|56119110 family with sequence similarity 13, member A1 isofor... 91 3e-18
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 91 4e-18
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 91 4e-18
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 90 7e-18
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 90 7e-18
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 89 1e-17
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 89 1e-17
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 89 2e-17
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 89 2e-17
gi|23510413 sorting nexin 26 [Homo sapiens] 88 3e-17
gi|54860079 nadrin isoform 1 [Homo sapiens] 87 5e-17
gi|54860105 nadrin isoform 2 [Homo sapiens] 87 5e-17
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 84 3e-16
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 84 4e-16
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 1300 bits (3363), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 1 MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV 60
MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV
Sbjct: 1 MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV 60
Query: 61 VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK 120
VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK
Sbjct: 61 VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK 120
Query: 121 KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ 180
KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ
Sbjct: 121 KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ 180
Query: 181 IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV 240
IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV
Sbjct: 181 IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV 240
Query: 241 DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV 300
DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV
Sbjct: 241 DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV 300
Query: 301 QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF 360
QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF
Sbjct: 301 QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF 360
Query: 361 FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI 420
FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI
Sbjct: 361 FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI 420
Query: 421 KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN 480
KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN
Sbjct: 421 KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN 480
Query: 481 ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS 540
ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS
Sbjct: 481 ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS 540
Query: 541 ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK 600
ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK
Sbjct: 541 ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK 600
Query: 601 AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI 655
AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI
Sbjct: 601 AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI 655
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 107 bits (267), Expect = 3e-23
Identities = 57/165 (34%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG+ +A +R + ++P + R+C++ +E+ GM+ GIYRVSG+ + + LKAA+D
Sbjct: 1007 VFGVKIAVVTKR----ERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD 1062
Query: 249 ---REESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
++ S + + + N +A LK Y R+LPE L T E P F E + K
Sbjct: 1063 VNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLN 1122
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
LL LPE N L +L+ H+ V KE KM++ N++ V PT+
Sbjct: 1123 LLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTL 1167
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 107 bits (267), Expect = 3e-23
Identities = 57/165 (34%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG+ +A +R + ++P + R+C++ +E+ GM+ GIYRVSG+ + + LKAA+D
Sbjct: 1051 VFGVKIAVVTKR----ERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFD 1106
Query: 249 ---REESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
++ S + + + N +A LK Y R+LPE L T E P F E + K
Sbjct: 1107 VNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLN 1166
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
LL LPE N L +L+ H+ V KE KM++ N++ V PT+
Sbjct: 1167 LLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTL 1211
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 107 bits (266), Expect = 5e-23
Identities = 63/209 (30%), Positives = 111/209 (53%), Gaps = 29/209 (13%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG L + ++ + G +P V + C ++VE+YG+ +GIYR+SG+ S + +L+ ++
Sbjct: 17 VFGCDLQEHLQ----HSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNIQKLRQEFE 71
Query: 249 REESTNLED----YEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
E +L + + V+SL K Y R+LP+ LLT L +F EA G E E++ +
Sbjct: 72 SERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKIL 131
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPT--------------- 349
+L+ELP NY + +L+ H+ H+ + +T M+ +N++IV +P
Sbjct: 132 EVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGT 191
Query: 350 -----VQISNRVLYVFFTHVQELFGNVVL 373
V++ + V+ THV +LFG L
Sbjct: 192 AAFMEVRVQSIVVEFILTHVDQLFGGAAL 220
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 107 bits (266), Expect = 5e-23
Identities = 63/209 (30%), Positives = 111/209 (53%), Gaps = 29/209 (13%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG L + ++ + G +P V + C ++VE+YG+ +GIYR+SG+ S + +L+ ++
Sbjct: 17 VFGCDLQEHLQ----HSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNIQKLRQEFE 71
Query: 249 REESTNLED----YEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
E +L + + V+SL K Y R+LP+ LLT L +F EA G E E++ +
Sbjct: 72 SERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKIL 131
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPT--------------- 349
+L+ELP NY + +L+ H+ H+ + +T M+ +N++IV +P
Sbjct: 132 EVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGT 191
Query: 350 -----VQISNRVLYVFFTHVQELFGNVVL 373
V++ + V+ THV +LFG L
Sbjct: 192 AAFMEVRVQSIVVEFILTHVDQLFGGAAL 220
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 105 bits (263), Expect = 1e-22
Identities = 86/294 (29%), Positives = 135/294 (45%), Gaps = 28/294 (9%)
Query: 66 KDHGKK---KGKFKKK---EKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSK 119
K HG++ K K+K K K Y D+S DEA + SK KR KG H +
Sbjct: 1143 KSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKR-KGRHRGSEEDPLL 1201
Query: 120 KKEKDFKIK-EKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEV 178
+ +K + P +E K+ K K K VK+ K++KKK K P
Sbjct: 1202 SPVETWKGGIDNPAITSDQELDDKKMKKKTHK---------VKEDKKQKKKTKNFNPPTR 1252
Query: 179 PQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKS 238
+ FG+PL D V +P +C++++E G+ EG+YRVSG K+
Sbjct: 1253 RNWE----SNYFGMPLQDLVTAEKP-----IPLFVEKCVEFIEDTGLCTEGLYRVSGNKT 1303
Query: 239 KVDELKAAYDREESTNLEDYEP--NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTE 296
D ++ +D++ + NL E N VA LK + DLP+ L+ L P EA +
Sbjct: 1304 DQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDK 1363
Query: 297 TEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
TE++ + ++K+ NY + ++I H++ V + M N+SI PT+
Sbjct: 1364 TERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTL 1417
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 105 bits (261), Expect = 2e-22
Identities = 86/297 (28%), Positives = 136/297 (45%), Gaps = 35/297 (11%)
Query: 66 KDHGKK---KGKFKKK---EKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKK--PSF 117
K HG++ K K+K K K Y D+S DEA + SK KR KG H + P
Sbjct: 1143 KSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKR-KGRHRGSEEDPLL 1201
Query: 118 SKKKEKDFKIKEKP--KEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQE 175
S + I +++ ++K K++ HK K+ K KKKK K
Sbjct: 1202 SPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDK-------------KKKKTKNFNP 1248
Query: 176 PEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG 235
P + FG+PL D V +P +C++++E G+ EG+YRVSG
Sbjct: 1249 PTRRNWE----SNYFGMPLQDLVTAEKP-----IPLFVEKCVEFIEDTGLCTEGLYRVSG 1299
Query: 236 IKSKVDELKAAYDREESTNLEDYEP--NTVASLLKQYLRDLPENLLTKELMPRFEEACGR 293
K+ D ++ +D++ + NL E N VA LK + DLP+ L+ L P EA
Sbjct: 1300 NKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKI 1359
Query: 294 TTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+TE++ + ++K+ NY + ++I H++ V + M N+SI PT+
Sbjct: 1360 PDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTL 1416
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 102 bits (255), Expect = 9e-22
Identities = 60/192 (31%), Positives = 100/192 (52%), Gaps = 8/192 (4%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG+ ++ +R + ++P + R+C++ VEK G++ GIYR+SG+ + + LKA +D
Sbjct: 598 VFGVKISVVTKR----ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD 653
Query: 249 REEST---NLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
L D + N +A LK Y R+LPE LLT L P F E + K
Sbjct: 654 ANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMH 713
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRV-LYVFFTHV 364
LL+ LP+ N + +L+ H+ V KE KM++ N++ V PT+ + V T
Sbjct: 714 LLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSA 773
Query: 365 QELFGNVVLKQV 376
+++ + V+ QV
Sbjct: 774 ADIWSHDVMAQV 785
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 102 bits (255), Expect = 9e-22
Identities = 60/192 (31%), Positives = 100/192 (52%), Gaps = 8/192 (4%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG+ ++ +R + ++P + R+C++ VEK G++ GIYR+SG+ + + LKA +D
Sbjct: 644 VFGVKISVVTKR----ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD 699
Query: 249 REEST---NLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
L D + N +A LK Y R+LPE LLT L P F E + K
Sbjct: 700 ANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMH 759
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRV-LYVFFTHV 364
LL+ LP+ N + +L+ H+ V KE KM++ N++ V PT+ + V T
Sbjct: 760 LLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSA 819
Query: 365 QELFGNVVLKQV 376
+++ + V+ QV
Sbjct: 820 ADIWSHDVMAQV 831
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 102 bits (255), Expect = 9e-22
Identities = 60/192 (31%), Positives = 100/192 (52%), Gaps = 8/192 (4%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG+ ++ +R + ++P + R+C++ VEK G++ GIYR+SG+ + + LKA +D
Sbjct: 607 VFGVKISVVTKR----ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD 662
Query: 249 REEST---NLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
L D + N +A LK Y R+LPE LLT L P F E + K
Sbjct: 663 ANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMH 722
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRV-LYVFFTHV 364
LL+ LP+ N + +L+ H+ V KE KM++ N++ V PT+ + V T
Sbjct: 723 LLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSA 782
Query: 365 QELFGNVVLKQV 376
+++ + V+ QV
Sbjct: 783 ADIWSHDVMAQV 794
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 97.1 bits (240), Expect = 5e-20
Identities = 69/286 (24%), Positives = 135/286 (47%), Gaps = 31/286 (10%)
Query: 89 QEDSSGDEAESP---SKMKRSKGIHVFKKP------------------SFSKKKEKDF-K 126
Q + SG+ ++S S ++R + + + KP SFS + +
Sbjct: 1126 QSNGSGNGSDSEMDTSSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGP 1185
Query: 127 IKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQIDVPNL 186
I++K +++ + K + +D ++++ + KK KP P + + +
Sbjct: 1186 IRKKEEDQASQGYKGDNAVIPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWES- 1244
Query: 187 KPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAA 246
FG+PL T++ +P CI+Y+E G+ EGIYRVSG KS+++ L+
Sbjct: 1245 -NYFGVPLT-----TVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQ 1298
Query: 247 YDREESTNL--EDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
+D++ + +L +D+ NTVA +K + +LP+ L+ + EA +K+ +
Sbjct: 1299 FDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALK 1358
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+LK+ P+ N+ + ++I H++ V M +N+SI PT+
Sbjct: 1359 EVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTL 1404
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 95.9 bits (237), Expect = 1e-19
Identities = 88/361 (24%), Positives = 166/361 (45%), Gaps = 40/361 (11%)
Query: 209 LPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDRE-ESTNLEDYEPNTVASLL 267
+P V + I+Y+E +G+ EGIYR SG +K+ EL+ D + ES NL+DY + +AS+
Sbjct: 2075 VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVF 2134
Query: 268 KQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDH 327
KQ+LRDLP L+T EL F A G E ++ ++ +L + + LI H+
Sbjct: 2135 KQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVR 2194
Query: 328 VIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVVLKQVMKPLRWSNMAT 387
+ +E +M+ ++IV +P + + + +V + + K +
Sbjct: 2195 IALQEDTNRMSANALAIVFAPCI--------LRCPDTTDPLQSV--QDISKTTTCVELIV 2244
Query: 388 MPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAK 447
+ + + +A +K +I EF N + RL ++R + K ++R
Sbjct: 2245 VEQMNKYKARLK-DISSLEFAEN-------------KAKTRLSLIRRSMG--KGRIRRGN 2288
Query: 448 RQECETKIAQEIASLSKEDVSKEEMNENEEVINILLAQENEILTEQEELLAMEQFLRRQI 507
+ + + S+S DVS+E + +E + + ++ + +QEE + EQ +
Sbjct: 2289 YPGPSSPVVVRLPSVS--DVSEETLT-SEAAMETDITEQQQAAMQQEERVLTEQI--ENL 2343
Query: 508 ASEKEE-------IERLRAEIAEIQSRQQHGRSE-TEEYSSESESESEDEEELQIILEDL 559
EKEE +E ++ ++S G ++ +E + ESE ++ E + L L
Sbjct: 2344 QKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLALSSL 2403
Query: 560 Q 560
+
Sbjct: 2404 K 2404
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 94.4 bits (233), Expect = 3e-19
Identities = 69/238 (28%), Positives = 118/238 (49%), Gaps = 16/238 (6%)
Query: 125 FKIKEKPKEE--KHKEEKHKEEKHKEKKSKDL----TAADVVKQWKEKKKKKKPI-QEPE 177
FKI+ E H + KE+K + +KS +A+D + + K + KK I + P
Sbjct: 205 FKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPS 264
Query: 178 VPQIDVPNL--KPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG 235
+ + L IFG L ER + +P ++CI+ VEK G+ +GIYRVSG
Sbjct: 265 LKTLQEKGLIKDQIFGSHLHKVCER----ENSTVPWFVKQCIEAVEKRGLDVDGIYRVSG 320
Query: 236 IKSKVDELKAAYDREESTNLEDYE---PNTVASLLKQYLRDLPENLLTKELMPRFEEACG 292
+ + +L+ ++EE NL+D + + V LK + R+LPE L +F EA
Sbjct: 321 NLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK 380
Query: 293 RTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ +++ + L+++LP N + L H+ ++AK + M+ Q++ IV PT+
Sbjct: 381 KQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTL 438
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 94.0 bits (232), Expect = 4e-19
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 29/205 (14%)
Query: 190 FGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDR 249
FG L + +E + G +P V + C +++E +G+ +GIYR+SG+ S + L+ +
Sbjct: 19 FGCDLTEYLESS----GQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNIQRLRQEFGS 73
Query: 250 EESTNL--EDY--EPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQR 305
++ +L E Y + + V SL K Y R+LP LLT EL +F EA E ++ Q
Sbjct: 74 DQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQN 133
Query: 306 LLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSP----------------- 348
+++ELP +Y + +LI H+ H+ + +T M+ +N+++V +P
Sbjct: 134 VIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDA 193
Query: 349 ---TVQISNRVLYVFFTHVQELFGN 370
V++ V+ HV ++F N
Sbjct: 194 AFLAVRVQQVVIEFILNHVDQIFNN 218
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 91.7 bits (226), Expect = 2e-18
Identities = 55/170 (32%), Positives = 95/170 (55%), Gaps = 9/170 (5%)
Query: 187 KPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAA 246
K IFG L D V Y P + +C+D++ + G+K EG++R+ G + V EL+ A
Sbjct: 37 KGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDA 96
Query: 247 YDREESTNLE-DYEPNTVASLLKQYLRDLPENLLTKELMPRFEE--ACGRTTETEK---V 300
+D E + + + + +TVASLLK YLR+LPE ++ ++E+ +C + E+ V
Sbjct: 97 FDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIP---YAKYEDFLSCAKLLSKEEEAGV 153
Query: 301 QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+E + +K LP NY L+ ++ +D V + KM++QN++ V P +
Sbjct: 154 KELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI 203
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 91.3 bits (225), Expect = 3e-18
Identities = 66/231 (28%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 126 KIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPI-QEPEVPQIDVP 184
+I + P EKH +EK +++ K + K +++ D +Q K KK KK + + P + +
Sbjct: 588 EIPDSPGIEKHDKEKEQKDPKKLRSFK-VSSIDSSEQKKTKKNLKKFLTRRPTLQAVREK 646
Query: 185 NL--KPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDE 242
+FG LA+ +R + +P + CI++VE++G+ +GIYRVSG + + +
Sbjct: 647 GYIKDQVFGSNLANLCQR----ENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQK 702
Query: 243 LKAAYDREESTNLED---YEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEK 299
L+ A + +E +L D + + + LK + R+LPE L T F A + ++
Sbjct: 703 LRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAI-KQEPRQR 761
Query: 300 VQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
V + L+++LP+ N + L H+ VI + +M Q+I+IV PT+
Sbjct: 762 VAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTL 812
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 90.9 bits (224), Expect = 3e-18
Identities = 55/184 (29%), Positives = 100/184 (54%), Gaps = 4/184 (2%)
Query: 166 KKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGM 225
K+ KK + P Q D K +FG+ L + + + +GI PAV ++Y+ ++G+
Sbjct: 18 KEDMKKIVAVPLNEQKDFTYQK-LFGVSLQELERQGLTENGI--PAVVWNIVEYLTQHGL 74
Query: 226 KCEGIYRVSGIKSKVDELKAAYDREESTNL-EDYEPNTVASLLKQYLRDLPENLLTKELM 284
EG++RV+G V++L+ ++ L +D + + ASLLK +LR+LP++L+T L
Sbjct: 75 TQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLKLFLRELPDSLITSALQ 134
Query: 285 PRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISI 344
PRF + + + L+KELP+ +Y L+ +L + V ++ +MN+ N++
Sbjct: 135 PRFIQLFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLAT 194
Query: 345 VLSP 348
V P
Sbjct: 195 VFGP 198
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 90.5 bits (223), Expect = 4e-18
Identities = 54/168 (32%), Positives = 94/168 (55%), Gaps = 9/168 (5%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
IFG L D V Y P + +C+D++ + G+K EG++R+ G + V EL+ A+D
Sbjct: 37 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 96
Query: 249 REESTNLE-DYEPNTVASLLKQYLRDLPENLLTKELMPRFEE--ACGRTTETEK---VQE 302
E + + + + +TVASLLK YLR+LPE ++ ++E+ +C + E+ V+E
Sbjct: 97 CGEKPSFDSNTDVHTVASLLKLYLRELPEPVIP---YAKYEDFLSCAKLLSKEEEAGVKE 153
Query: 303 FQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ +K LP NY L+ ++ +D V + KM++QN++ V P +
Sbjct: 154 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI 201
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 90.5 bits (223), Expect = 4e-18
Identities = 54/168 (32%), Positives = 94/168 (55%), Gaps = 9/168 (5%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
IFG L D V Y P + +C+D++ + G+K EG++R+ G + V EL+ A+D
Sbjct: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 191
Query: 249 REESTNLE-DYEPNTVASLLKQYLRDLPENLLTKELMPRFEE--ACGRTTETEK---VQE 302
E + + + + +TVASLLK YLR+LPE ++ ++E+ +C + E+ V+E
Sbjct: 192 CGEKPSFDSNTDVHTVASLLKLYLRELPEPVIP---YAKYEDFLSCAKLLSKEEEAGVKE 248
Query: 303 FQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ +K LP NY L+ ++ +D V + KM++QN++ V P +
Sbjct: 249 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI 296
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 89.7 bits (221), Expect = 7e-18
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 8/176 (4%)
Query: 182 DVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVD 241
D+ ++K ++ L V+ + P V CI +E G+ EG+YRVSG ++
Sbjct: 258 DLKHVKKVYSCDLTTLVKAHTT----KRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIE 313
Query: 242 ELKAAYDRE---ESTNLEDYEP-NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTET 297
++K A+DR+ ++ YE N + LK Y RDLP L+T + P+F E+
Sbjct: 314 DVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPD 373
Query: 298 EKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQIS 353
E+++ LK LP + + +L+ H+ V E E MN +N+ IV PT+ S
Sbjct: 374 EQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS 429
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 89.7 bits (221), Expect = 7e-18
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 8/176 (4%)
Query: 182 DVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVD 241
D+ ++K ++ L V+ + P V CI +E G+ EG+YRVSG ++
Sbjct: 232 DLKHVKKVYSCDLTTLVKAHTT----KRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIE 287
Query: 242 ELKAAYDRE---ESTNLEDYEP-NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTET 297
++K A+DR+ ++ YE N + LK Y RDLP L+T + P+F E+
Sbjct: 288 DVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPD 347
Query: 298 EKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQIS 353
E+++ LK LP + + +L+ H+ V E E MN +N+ IV PT+ S
Sbjct: 348 EQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS 403
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 89.0 bits (219), Expect = 1e-17
Identities = 51/172 (29%), Positives = 97/172 (56%), Gaps = 9/172 (5%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG L + ++ G +P V + C ++E+YG+ +GIYR+SG+ S + L+ +D
Sbjct: 369 VFGCDLGEH----LLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFD 423
Query: 249 REESTNL--EDY--EPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
E +L E Y + ++V SL K Y R+LP LLT +L +F +A T+ E++ +
Sbjct: 424 SEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIH 483
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRV 356
++++LP +Y + +L+ H+ + T M+ +N++IV +P + S ++
Sbjct: 484 DVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQI 535
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 89.0 bits (219), Expect = 1e-17
Identities = 51/172 (29%), Positives = 97/172 (56%), Gaps = 9/172 (5%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG L + ++ G +P V + C ++E+YG+ +GIYR+SG+ S + L+ +D
Sbjct: 20 VFGCDLGEH----LLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFD 74
Query: 249 REESTNL--EDY--EPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
E +L E Y + ++V SL K Y R+LP LLT +L +F +A T+ E++ +
Sbjct: 75 SEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIH 134
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRV 356
++++LP +Y + +L+ H+ + T M+ +N++IV +P + S ++
Sbjct: 135 DVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQI 186
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 88.6 bits (218), Expect = 2e-17
Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Query: 178 VPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIK 237
VP P+LK I + D ++ R P V CI +E G+K EG+YRVSG
Sbjct: 260 VPNDCQPDLKRIKKVYCCDLTTLVKAHNTQR-PMVVDICIREIEARGLKSEGLYRVSGFT 318
Query: 238 SKVDELKAAYDREE-----STNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACG 292
++++K A+DR+ S N+ + N + LK Y RDLP ++T + +F +A
Sbjct: 319 EHIEDVKMAFDRDGEKADISANVYP-DINIITGALKLYFRDLPIPVITYDTYSKFIDAAK 377
Query: 293 RTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ E+++ +L LP +Y + +L++H+ V E + MN +N+ IV PT+
Sbjct: 378 ISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 88.6 bits (218), Expect = 2e-17
Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Query: 178 VPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIK 237
VP P+LK I + D ++ R P V CI +E G+K EG+YRVSG
Sbjct: 124 VPNDCQPDLKRIKKVYCCDLTTLVKAHNTQR-PMVVDICIREIEARGLKSEGLYRVSGFT 182
Query: 238 SKVDELKAAYDREE-----STNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACG 292
++++K A+DR+ S N+ + N + LK Y RDLP ++T + +F +A
Sbjct: 183 EHIEDVKMAFDRDGEKADISANVYP-DINIITGALKLYFRDLPIPVITYDTYSKFIDAAK 241
Query: 293 RTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ E+++ +L LP +Y + +L++H+ V E + MN +N+ IV PT+
Sbjct: 242 ISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 299
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 87.8 bits (216), Expect = 3e-17
Identities = 57/215 (26%), Positives = 103/215 (47%), Gaps = 29/215 (13%)
Query: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248
+FG L + + + G +P V R C +++E +G+ +GIYR+SG+ S + L+ +D
Sbjct: 312 VFGCDLGEHLSNS----GQDVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFD 366
Query: 249 REESTNLED----YEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQ 304
E L + ++V+SL K Y R+LP LLT +L +F EA E E++
Sbjct: 367 SERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVH 426
Query: 305 RLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPT--------------- 349
++++LP +Y + +L+ H+ + T M+ +N++IV +P
Sbjct: 427 DVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGA 486
Query: 350 -----VQISNRVLYVFFTHVQELFGNVVLKQVMKP 379
V++ + V+ THV LF + + P
Sbjct: 487 AAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDP 521
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 87.0 bits (214), Expect = 5e-17
Identities = 67/235 (28%), Positives = 113/235 (48%), Gaps = 26/235 (11%)
Query: 138 EEKHKEEKHKEKKSKDLTAADV-----------------VKQWKEKKKKKKPIQEPEVPQ 180
+E+ E +K ++ KD AAD+ ++ + +K + E +P+
Sbjct: 177 KEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPE 236
Query: 181 I----DVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGI 236
+ D KP FG PL + ++R+ G + C+ + + GMK EG++R+
Sbjct: 237 MRAHQDKWAEKPAFGTPLEEHLKRS----GREIALPIEACVMLLLETGMKEEGLFRIGAG 292
Query: 237 KSKVDELKAAYDREESTNLEDY-EPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTT 295
SK+ +LKAA D S E Y +P+ VA LK YLR+LPE L+T L + +
Sbjct: 293 ASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQD 352
Query: 296 ETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ +K+Q+ R ++LP N++ +LI + + KM NI+IVL P +
Sbjct: 353 QDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNL 407
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 87.0 bits (214), Expect = 5e-17
Identities = 67/235 (28%), Positives = 113/235 (48%), Gaps = 26/235 (11%)
Query: 138 EEKHKEEKHKEKKSKDLTAADV-----------------VKQWKEKKKKKKPIQEPEVPQ 180
+E+ E +K ++ KD AAD+ ++ + +K + E +P+
Sbjct: 177 KEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPE 236
Query: 181 I----DVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGI 236
+ D KP FG PL + ++R+ G + C+ + + GMK EG++R+
Sbjct: 237 MRAHQDKWAEKPAFGTPLEEHLKRS----GREIALPIEACVMLLLETGMKEEGLFRIGAG 292
Query: 237 KSKVDELKAAYDREESTNLEDY-EPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTT 295
SK+ +LKAA D S E Y +P+ VA LK YLR+LPE L+T L + +
Sbjct: 293 ASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQD 352
Query: 296 ETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
+ +K+Q+ R ++LP N++ +LI + + KM NI+IVL P +
Sbjct: 353 QDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNL 407
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 84.3 bits (207), Expect = 3e-16
Identities = 49/167 (29%), Positives = 95/167 (56%), Gaps = 6/167 (3%)
Query: 189 IFGIPLADAVERTMM-YDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG----IKSKVDEL 243
+F +PL +E+ G+R+P +F++ I +E+ G++ EG+ R+ G IK+ EL
Sbjct: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
Query: 244 KAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEF 303
+A + E + N E + + ASLLK ++R+LP+ LL+ E + F+ T+ +++Q
Sbjct: 381 EAKF-YEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439
Query: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
L+ LP+ N + L+ + VI + + KM + N+++V++P +
Sbjct: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 84.0 bits (206), Expect = 4e-16
Identities = 54/168 (32%), Positives = 88/168 (52%), Gaps = 3/168 (1%)
Query: 209 LPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDRE-ESTNLEDYEPNT--VAS 265
+P + C+DY+ + G+ EGIYR G SK L + ++ S +L++ E + V+S
Sbjct: 664 IPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSS 723
Query: 266 LLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHM 325
LK++LRDLP+ L T+ + EA E EKV ++ LL LP N + LI H+
Sbjct: 724 ALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHL 783
Query: 326 DHVIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVVL 373
V +MN+ N++IV PT+ ++ Y V++L + V+
Sbjct: 784 YCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVV 831
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,135,762
Number of Sequences: 37866
Number of extensions: 1456112
Number of successful extensions: 28356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 758
Number of HSP's successfully gapped in prelim test: 1211
Number of HSP's that attempted gapping in prelim test: 10448
Number of HSP's gapped (non-prelim): 10936
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.