Guide to the Human Genome
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Search of human proteins with 5802992

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5802992 cyclin I [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5802992 cyclin I [Homo sapiens]                                    760   0.0  
gi|89886237 cyclin I family, member 2 [Homo sapiens]                  196   2e-50
gi|4757936 cyclin G2 [Homo sapiens]                                   123   2e-28
gi|40805832 cyclin G1 [Homo sapiens]                                  106   3e-23
gi|4757934 cyclin G1 [Homo sapiens]                                   106   3e-23
gi|17318565 cyclin E2 [Homo sapiens]                                   74   2e-13
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                         67   3e-11
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                         67   3e-11
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    62   8e-10
gi|4502617 cyclin D2 [Homo sapiens]                                    60   4e-09
gi|16950655 cyclin D1 [Homo sapiens]                                   59   9e-09
gi|197276676 cyclin J isoform 3 [Homo sapiens]                         54   2e-07
gi|197276674 cyclin J isoform 1 [Homo sapiens]                         54   2e-07
gi|40254889 cyclin J isoform 2 [Homo sapiens]                          54   3e-07
gi|4757930 cyclin B2 [Homo sapiens]                                    50   3e-06
gi|4502613 cyclin A [Homo sapiens]                                     50   3e-06
gi|153791755 cyclin domain containing [Homo sapiens]                   50   4e-06
gi|14327896 cyclin B1 [Homo sapiens]                                   49   1e-05
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         49   1e-05
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                          47   2e-05
gi|161377472 cyclin A1 isoform c [Homo sapiens]                        46   5e-05
gi|161377470 cyclin A1 isoform c [Homo sapiens]                        46   5e-05
gi|161377468 cyclin A1 isoform b [Homo sapiens]                        46   5e-05
gi|4502611 cyclin A1 isoform a [Homo sapiens]                          46   5e-05
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                         40   0.003
gi|73760401 thymopoietin isoform gamma [Homo sapiens]                  38   0.017
gi|73760405 thymopoietin isoform beta [Homo sapiens]                   38   0.017
gi|4507555 thymopoietin isoform alpha [Homo sapiens]                   38   0.017
gi|209862835 cyclin D3 isoform 1 [Homo sapiens]                        35   0.11 
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         34   0.19 

>gi|5802992 cyclin I [Homo sapiens]
          Length = 377

 Score =  760 bits (1962), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN 60
           MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN
Sbjct: 1   MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN 60

Query: 61  LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC 120
           LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC
Sbjct: 61  LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC 120

Query: 121 GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV 180
           GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV
Sbjct: 121 GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV 180

Query: 181 LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR 240
           LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR
Sbjct: 181 LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR 240

Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
           ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV
Sbjct: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300

Query: 301 RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR 360
           RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR
Sbjct: 301 RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR 360

Query: 361 QEGHASPCPPLQPVSVM 377
           QEGHASPCPPLQPVSVM
Sbjct: 361 QEGHASPCPPLQPVSVM 377


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score =  196 bits (499), Expect = 2e-50
 Identities = 111/249 (44%), Positives = 155/249 (62%), Gaps = 5/249 (2%)

Query: 5   GPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPE 64
           G L+ +RL   L+ A  REA++W+         Q+      +EV+ WL +L+  F     
Sbjct: 115 GDLDERRLLCHLQLAQDREARLWRGG-----KPQDEICDAFEEVVLWLLRLQNTFYFSQS 169

Query: 65  TFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSS 124
           TF LA ++  R L +VK   KYL C  I+   LAAK  EE+E IP +K   +      S 
Sbjct: 170 TFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSP 229

Query: 125 SEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQ 184
           +E+LRME  ILD+L+WDL+  TPLDFL IFHA+ V + P +L  LP+ +PS H+A LT+Q
Sbjct: 230 NELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQ 289

Query: 185 LLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCRELVA 244
           L HCMA +QLLQF+GS LAL +++LE+E+L+P W +   +LL+KAQ+   Q   C+ELV 
Sbjct: 290 LQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVM 349

Query: 245 HHLSTLQSS 253
             L +LQSS
Sbjct: 350 QQLRSLQSS 358


>gi|4757936 cyclin G2 [Homo sapiens]
          Length = 344

 Score =  123 bits (309), Expect = 2e-28
 Identities = 81/227 (35%), Positives = 126/227 (55%), Gaps = 15/227 (6%)

Query: 31  VRKMPSNQN-VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSC 89
           +   P N N + P  R+  ++ L  L   F    ETF LA ++LDRFLA +K  PK+LSC
Sbjct: 41  IEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSC 100

Query: 90  IAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
           I +  F LAA+ VEED  IP    + R S C C++S+I RME+II +KL+++L   T L+
Sbjct: 101 IGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALN 160

Query: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQF---RGSMLALAM 206
           FLH++H I           L   S  + +  L K      ACN  L F   + S+LAL +
Sbjct: 161 FLHLYHTII----------LCHTSERKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCL 210

Query: 207 VSLEMEKL-IPDWLSLTIELLQKAQMDSSQLIHCRELVAHHLSTLQS 252
           ++LE+E L   + L + + + + ++++ ++  + RELV+  L+   S
Sbjct: 211 LNLEVETLKSVELLEILLLVKKHSKINDTEFFYWRELVSKCLAEYSS 257


>gi|40805832 cyclin G1 [Homo sapiens]
          Length = 295

 Score =  106 bits (265), Expect = 3e-23
 Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 7/210 (3%)

Query: 45  RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
           RD  ++ L  L   F    ETF+LA +LLDRFL+ +K  PK+L C+ +SCF+LA K++EE
Sbjct: 52  RDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEE 111

Query: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQ 164
           +  +P+   L R S    + S+++RME+I+L+K+ W +   T   FL +++++     P 
Sbjct: 112 ERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPL 171

Query: 165 LLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIE 224
                 +   S +   L  QL  C       + + S+LAL++++LE++      L+  IE
Sbjct: 172 ------ERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE 225

Query: 225 LLQK-AQMDSSQLIHCRELVAHHLSTLQSS 253
            LQK ++++   L   +ELV+  L+   S+
Sbjct: 226 CLQKHSKINGRDLTFWQELVSKCLTEYSSN 255


>gi|4757934 cyclin G1 [Homo sapiens]
          Length = 295

 Score =  106 bits (265), Expect = 3e-23
 Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 7/210 (3%)

Query: 45  RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
           RD  ++ L  L   F    ETF+LA +LLDRFL+ +K  PK+L C+ +SCF+LA K++EE
Sbjct: 52  RDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEE 111

Query: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQ 164
           +  +P+   L R S    + S+++RME+I+L+K+ W +   T   FL +++++     P 
Sbjct: 112 ERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPL 171

Query: 165 LLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIE 224
                 +   S +   L  QL  C       + + S+LAL++++LE++      L+  IE
Sbjct: 172 ------ERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE 225

Query: 225 LLQK-AQMDSSQLIHCRELVAHHLSTLQSS 253
            LQK ++++   L   +ELV+  L+   S+
Sbjct: 226 CLQKHSKINGRDLTFWQELVSKCLTEYSSN 255


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 63/224 (28%), Positives = 112/224 (50%), Gaps = 20/224 (8%)

Query: 37  NQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVK-AHPKYLSCIAISCF 95
           + ++ P  R  ++ WL ++   + L+ ETF LA    DRF+ T K  +   L  I I+  
Sbjct: 134 HSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSL 193

Query: 96  FLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFH 155
           F+A+K   E+   P L+  A  +   CS  +ILRME IIL  L W+L   T + +L++F 
Sbjct: 194 FIASKL--EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL 251

Query: 156 AI-AVSTRPQLLFSLPKLSPSQHLAVLTKQLLH-CMACNQLLQFRGSMLALAMVSLEMEK 213
            + A+   P++L  LP+   SQ   +   QLL  C+     L+F+  +L  A +      
Sbjct: 252 QVDALKDAPKVL--LPQY--SQETFIQIAQLLDLCILAIDSLEFQYRILTAAALC----- 302

Query: 214 LIPDWLSLTIELLQKAQ-MDSSQLIHCRELVAHHLSTLQSSLPL 256
                   +IE+++KA  ++   +  C + +   ++ ++S+ P+
Sbjct: 303 -----HFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPV 341


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 71/260 (27%), Positives = 120/260 (46%), Gaps = 33/260 (12%)

Query: 25  QMWKVNVRK----------MPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLD 74
           ++WK+ + K          +  +  + P  R  ++ WL ++   + L+ ETF LA    D
Sbjct: 115 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 174

Query: 75  RFLATVKAHPK-YLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERI 133
           R++AT +   K  L  I IS  F+AAK   E+   P L   A  +   CS  EIL ME +
Sbjct: 175 RYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELM 232

Query: 134 ILDKLNWDLHTATPLDFLHIFHAIA-VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACN 192
           I+  L W L   T + +L+++  +A ++   ++L  LP+  P Q    + + L  C+   
Sbjct: 233 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVL--LPQY-PQQIFIQIAELLDLCVLDV 289

Query: 193 QLLQFRGSMLALAMV----SLEMEKLIPDWLSLTIELLQK---------AQMDSSQLIHC 239
             L+F   +LA + +    S E+ + +  +    IE   K          +  SS+L H 
Sbjct: 290 DCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHF 349

Query: 240 RELV---AHHLSTLQSSLPL 256
           R +    AH++ T + SL L
Sbjct: 350 RGVADEDAHNIQTHRDSLDL 369


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 71/260 (27%), Positives = 120/260 (46%), Gaps = 33/260 (12%)

Query: 25  QMWKVNVRK----------MPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLD 74
           ++WK+ + K          +  +  + P  R  ++ WL ++   + L+ ETF LA    D
Sbjct: 100 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 159

Query: 75  RFLATVKAHPK-YLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERI 133
           R++AT +   K  L  I IS  F+AAK   E+   P L   A  +   CS  EIL ME +
Sbjct: 160 RYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELM 217

Query: 134 ILDKLNWDLHTATPLDFLHIFHAIA-VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACN 192
           I+  L W L   T + +L+++  +A ++   ++L  LP+  P Q    + + L  C+   
Sbjct: 218 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVL--LPQY-PQQIFIQIAELLDLCVLDV 274

Query: 193 QLLQFRGSMLALAMV----SLEMEKLIPDWLSLTIELLQK---------AQMDSSQLIHC 239
             L+F   +LA + +    S E+ + +  +    IE   K          +  SS+L H 
Sbjct: 275 DCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHF 334

Query: 240 RELV---AHHLSTLQSSLPL 256
           R +    AH++ T + SL L
Sbjct: 335 RGVADEDAHNIQTHRDSLDL 354


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 45/128 (35%), Positives = 69/128 (53%), Gaps = 5/128 (3%)

Query: 40  VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAA 99
           V+P  R  V+ WL ++     L  +T  LA  LLD +L+  +     L  + ++C F+A 
Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162

Query: 100 KTVEEDERIPV-LKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIA 158
           K  E     P  L +L+ DSF   S +E+LR ER IL +L++ LH   PL  L +  A+A
Sbjct: 163 KMEECVLPEPAFLCLLSADSF---SRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALA 219

Query: 159 VSTRPQLL 166
            S+ PQ++
Sbjct: 220 GSS-PQVM 226


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)

Query: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
           +++ P  R  V  W+ ++  +     E F LA + LDRFLA V     +L  +   C FL
Sbjct: 49  KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108

Query: 98  AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156
           A+K  E          +  D+       E+L  E ++L KL W+L   TP DF+ HI   
Sbjct: 109 ASKLKETSPLTAEKLCIYTDN--SIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRK 166

Query: 157 I 157
           +
Sbjct: 167 L 167


>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 12/122 (9%)

Query: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
           + V PS R  V  W+ ++  +     E F LA + LDRFL+        L  +  +C F+
Sbjct: 50  KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109

Query: 98  AAKTVEEDERIPVLKVLARDSFC-----GCSSSEILRMERIILDKLNWDLHTATPLDFLH 152
           A+K     E IP    L  +  C          E+L+ME ++++KL W+L   TP DF+ 
Sbjct: 110 ASKM---KETIP----LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIE 162

Query: 153 IF 154
            F
Sbjct: 163 HF 164


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 19/175 (10%)

Query: 33  KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
           K+PS +  SP  S R      +A +  +F L P    LA  LLD F+       + L  +
Sbjct: 26  KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85

Query: 91  AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
           A+SC  LA+K  E+++ +P L+ L   +  GC        +   +L ME ++L+   W+L
Sbjct: 86  ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142

Query: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMAC 191
              T   F+  + + AV         P +     KL  +++     +  L   AC
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQAAAC 197


>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 24/204 (11%)

Query: 33  KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
           K+PS +  SP  S R      +A +  +F L P    LA  LLD F+       + L  +
Sbjct: 26  KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85

Query: 91  AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
           A+SC  LA+K  E+++ +P L+ L   +  GC        +   +L ME ++L+   W+L
Sbjct: 86  ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142

Query: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQ 196
              T   F+  + + AV         P +     KL  +++     +  L   A    L 
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYA---FLN 199

Query: 197 FRGSMLALAMV--SLEMEKLIPDW 218
           +  S++A A V  S  + +L P W
Sbjct: 200 YAPSLVAAACVASSRIILRLSPTW 223


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 13/137 (9%)

Query: 33  KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
           K+PS +  SP  S R      +A +  +F L P    LA  LLD F+       + L  +
Sbjct: 26  KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85

Query: 91  AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
           A+SC  LA+K  E+++ +P L+ L   +  GC        +   +L ME ++L+   W+L
Sbjct: 86  ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142

Query: 143 HTATPLDFLHIFHAIAV 159
              T   F+  + + AV
Sbjct: 143 CLPTAAHFIEYYLSEAV 159


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
           ++++   R  ++ WL ++  +F L  ET  +   ++DRFL       K L  + I+   L
Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218

Query: 98  AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
           A+K   E+   P ++     +    +SS+I  ME +IL +L ++L    PL FL
Sbjct: 219 ASK--YEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFL 270


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)

Query: 28  KVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYL 87
           K  V  M    +++ S R  ++ WL ++  ++ L  ET  LA + +DRFL+++      L
Sbjct: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253

Query: 88  SCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTAT 146
             +  +   LA+K  E     +     +  D++   +  ++LRME ++L  L +DL   T
Sbjct: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY---TKKQVLRMEHLVLKVLTFDLAAPT 310

Query: 147 PLDFL 151
              FL
Sbjct: 311 VNQFL 315


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 6/138 (4%)

Query: 22  REAQMWKVNVRKMPSNQ-NVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
           R+AQ    + R+  + Q  V+   R +++ WL  +  QF L  E+  L  + LDRFL T 
Sbjct: 109 RKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTT 168

Query: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
                    + ++   +A K VE    R+  L  L   +F   S  ++  +E I+L KL+
Sbjct: 169 PVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAF---SRQQLCNLECIVLHKLH 225

Query: 140 WDLHTATPLDFL-HIFHA 156
           + L   T   FL H  HA
Sbjct: 226 FTLGAPTISFFLEHFTHA 243


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)

Query: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
           + V+ + R  +I WL +++ +F L  ET  +  S++DRF+       K L  + ++  F+
Sbjct: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254

Query: 98  AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
           A+K   E+   P +   A  +    +  +I +ME  IL  LN+ L    PL FL
Sbjct: 255 ASK--YEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 19/178 (10%)

Query: 40   VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAA 99
            ++   R  ++ WL +++  F +  ET  LA  L+D +L         L  +  + F +AA
Sbjct: 1156 ITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAA 1215

Query: 100  KTVEEDE-RIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIA 158
            K  E +  R+     +  D++     SE+L ME  IL+ L  D++      FL  + A  
Sbjct: 1216 KFEEHNSPRVDDFVYICDDNY---QRSEVLSMEINILNVLKCDINIPIAYHFLRRY-ARC 1271

Query: 159  VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALA--MVSLEMEKL 214
            + T      ++  L+ S+++  +T Q  H       +Q + S LA A  +++L M+KL
Sbjct: 1272 IHT------NMKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLLALYMKKL 1317


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 3/130 (2%)

Query: 38  QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
           + + P  R  +  W+ ++  +     E F LA + LDR+L+ V      L  +   C  L
Sbjct: 50  REIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLL 109

Query: 98  AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156
           A+K + E   + + K+         S  ++   E ++L KL WDL      DFL  I H 
Sbjct: 110 ASK-LRETTPLTIEKLCIYTDH-AVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHR 167

Query: 157 IAVSTRPQLL 166
           +++    Q L
Sbjct: 168 LSLPRDRQAL 177


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 22  REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
           REA++  +     M    +++   R  ++ WL ++  ++ L  ET  LA + LDRFL+ +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235

Query: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
                 L  +  +   LA+K  E     +     +  D++   +  ++L+ME ++L  L 
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 292

Query: 140 WDLHTATPLDFL 151
           +DL   T   FL
Sbjct: 293 FDLTVPTTNQFL 304


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 22  REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
           REA++  +     M    +++   R  ++ WL ++  ++ L  ET  LA + LDRFL+ +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235

Query: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
                 L  +  +   LA+K  E     +     +  D++   +  ++L+ME ++L  L 
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 292

Query: 140 WDLHTATPLDFL 151
           +DL   T   FL
Sbjct: 293 FDLTVPTTNQFL 304


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 22  REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
           REA++  +     M    +++   R  ++ WL ++  ++ L  ET  LA + LDRFL+ +
Sbjct: 219 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 278

Query: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
                 L  +  +   LA+K  E     +     +  D++   +  ++L+ME ++L  L 
Sbjct: 279 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 335

Query: 140 WDLHTATPLDFL 151
           +DL   T   FL
Sbjct: 336 FDLTVPTTNQFL 347


>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 22  REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
           REA++  +     M    +++   R  ++ WL ++  ++ L  ET  LA + LDRFL+ +
Sbjct: 220 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 279

Query: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
                 L  +  +   LA+K  E     +     +  D++   +  ++L+ME ++L  L 
Sbjct: 280 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 336

Query: 140 WDLHTATPLDFL 151
           +DL   T   FL
Sbjct: 337 FDLTVPTTNQFL 348


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 23/187 (12%)

Query: 35  PSNQNVSPSQRDEVIQWLAKLK----YQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
           PS+   SPS     ++  +  +      F +  ET  LA  L+D +L         L  +
Sbjct: 43  PSSLQESPSSLQGALKKRSAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLL 102

Query: 91  AISCFFLAAKTVEEDE-RIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
             + F +AAK  E +  R+     +  D++     SE+L ME  IL+ L  D++      
Sbjct: 103 GATAFMIAAKFEEHNSPRVDDFVYICDDNY---QRSEVLSMEINILNVLKCDINIPIAYH 159

Query: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALA--MV 207
           FL  + A  + T      ++  L+ S+++  +T Q  H       +Q + S LA A  ++
Sbjct: 160 FLRRY-ARCIHT------NMKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLL 206

Query: 208 SLEMEKL 214
           +L M+KL
Sbjct: 207 ALYMKKL 213


>gi|73760401 thymopoietin isoform gamma [Homo sapiens]
          Length = 345

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)

Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
           ELVA+++ TL +      VYV   L+H L   ++       +S   PDFS D  +   PV
Sbjct: 19  ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76

Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
            G+ AA      AA G K T    K  + + DD    +  L NED + +      N G +
Sbjct: 77  LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134

Query: 354 CGT 356
            GT
Sbjct: 135 VGT 137


>gi|73760405 thymopoietin isoform beta [Homo sapiens]
          Length = 454

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)

Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
           ELVA+++ TL +      VYV   L+H L   ++       +S   PDFS D  +   PV
Sbjct: 19  ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76

Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
            G+ AA      AA G K T    K  + + DD    +  L NED + +      N G +
Sbjct: 77  LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134

Query: 354 CGT 356
            GT
Sbjct: 135 VGT 137


>gi|4507555 thymopoietin isoform alpha [Homo sapiens]
          Length = 694

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)

Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
           ELVA+++ TL +      VYV   L+H L   ++       +S   PDFS D  +   PV
Sbjct: 19  ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76

Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
            G+ AA      AA G K T    K  + + DD    +  L NED + +      N G +
Sbjct: 77  LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134

Query: 354 CGT 356
            GT
Sbjct: 135 VGT 137


>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
          Length = 211

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 73  LDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMER 132
           LDR+L+ V      L  +   C  LA+K + E   + + K+         S  ++   E 
Sbjct: 4   LDRYLSCVPTRKAQLQLLGAVCMLLASK-LRETTPLTIEKLCIYTDHA-VSPRQLRDWEV 61

Query: 133 IILDKLNWDLHTATPLDFL-HIFHAIAVSTRPQLL 166
           ++L KL WDL      DFL  I H +++    Q L
Sbjct: 62  LVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL 96


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 45  RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLA--TVKAHPKYLSCIAISCFFLAAKTV 102
           R E  +++  +  +  L+ +T A       RF    + K  P+Y++     C FLA K  
Sbjct: 50  RREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVT--GACCLFLAGKVE 107

Query: 103 EEDERIPVLKVLARD--------SFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
           E  ++   +   AR          F      E++ +ERI+L  + +DL    P  FL
Sbjct: 108 ETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFL 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,952,793
Number of Sequences: 37866
Number of extensions: 657534
Number of successful extensions: 1636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1593
Number of HSP's gapped (non-prelim): 37
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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