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Search of human proteins with 5802992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5802992 cyclin I [Homo sapiens]
(377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5802992 cyclin I [Homo sapiens] 760 0.0
gi|89886237 cyclin I family, member 2 [Homo sapiens] 196 2e-50
gi|4757936 cyclin G2 [Homo sapiens] 123 2e-28
gi|40805832 cyclin G1 [Homo sapiens] 106 3e-23
gi|4757934 cyclin G1 [Homo sapiens] 106 3e-23
gi|17318565 cyclin E2 [Homo sapiens] 74 2e-13
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 67 3e-11
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 67 3e-11
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 62 8e-10
gi|4502617 cyclin D2 [Homo sapiens] 60 4e-09
gi|16950655 cyclin D1 [Homo sapiens] 59 9e-09
gi|197276676 cyclin J isoform 3 [Homo sapiens] 54 2e-07
gi|197276674 cyclin J isoform 1 [Homo sapiens] 54 2e-07
gi|40254889 cyclin J isoform 2 [Homo sapiens] 54 3e-07
gi|4757930 cyclin B2 [Homo sapiens] 50 3e-06
gi|4502613 cyclin A [Homo sapiens] 50 3e-06
gi|153791755 cyclin domain containing [Homo sapiens] 50 4e-06
gi|14327896 cyclin B1 [Homo sapiens] 49 1e-05
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 49 1e-05
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 47 2e-05
gi|161377472 cyclin A1 isoform c [Homo sapiens] 46 5e-05
gi|161377470 cyclin A1 isoform c [Homo sapiens] 46 5e-05
gi|161377468 cyclin A1 isoform b [Homo sapiens] 46 5e-05
gi|4502611 cyclin A1 isoform a [Homo sapiens] 46 5e-05
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 40 0.003
gi|73760401 thymopoietin isoform gamma [Homo sapiens] 38 0.017
gi|73760405 thymopoietin isoform beta [Homo sapiens] 38 0.017
gi|4507555 thymopoietin isoform alpha [Homo sapiens] 38 0.017
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 35 0.11
gi|150417989 cyclin K isoform 1 [Homo sapiens] 34 0.19
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 760 bits (1962), Expect = 0.0
Identities = 377/377 (100%), Positives = 377/377 (100%)
Query: 1 MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN 60
MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN
Sbjct: 1 MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN 60
Query: 61 LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC 120
LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC
Sbjct: 61 LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC 120
Query: 121 GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV 180
GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV
Sbjct: 121 GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV 180
Query: 181 LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR 240
LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR
Sbjct: 181 LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR 240
Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV
Sbjct: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
Query: 301 RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR 360
RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR
Sbjct: 301 RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR 360
Query: 361 QEGHASPCPPLQPVSVM 377
QEGHASPCPPLQPVSVM
Sbjct: 361 QEGHASPCPPLQPVSVM 377
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 196 bits (499), Expect = 2e-50
Identities = 111/249 (44%), Positives = 155/249 (62%), Gaps = 5/249 (2%)
Query: 5 GPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPE 64
G L+ +RL L+ A REA++W+ Q+ +EV+ WL +L+ F
Sbjct: 115 GDLDERRLLCHLQLAQDREARLWRGG-----KPQDEICDAFEEVVLWLLRLQNTFYFSQS 169
Query: 65 TFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSS 124
TF LA ++ R L +VK KYL C I+ LAAK EE+E IP +K + S
Sbjct: 170 TFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSP 229
Query: 125 SEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQ 184
+E+LRME ILD+L+WDL+ TPLDFL IFHA+ V + P +L LP+ +PS H+A LT+Q
Sbjct: 230 NELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQ 289
Query: 185 LLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCRELVA 244
L HCMA +QLLQF+GS LAL +++LE+E+L+P W + +LL+KAQ+ Q C+ELV
Sbjct: 290 LQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVM 349
Query: 245 HHLSTLQSS 253
L +LQSS
Sbjct: 350 QQLRSLQSS 358
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 123 bits (309), Expect = 2e-28
Identities = 81/227 (35%), Positives = 126/227 (55%), Gaps = 15/227 (6%)
Query: 31 VRKMPSNQN-VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSC 89
+ P N N + P R+ ++ L L F ETF LA ++LDRFLA +K PK+LSC
Sbjct: 41 IEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSC 100
Query: 90 IAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
I + F LAA+ VEED IP + R S C C++S+I RME+II +KL+++L T L+
Sbjct: 101 IGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALN 160
Query: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQF---RGSMLALAM 206
FLH++H I L S + + L K ACN L F + S+LAL +
Sbjct: 161 FLHLYHTII----------LCHTSERKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCL 210
Query: 207 VSLEMEKL-IPDWLSLTIELLQKAQMDSSQLIHCRELVAHHLSTLQS 252
++LE+E L + L + + + + ++++ ++ + RELV+ L+ S
Sbjct: 211 LNLEVETLKSVELLEILLLVKKHSKINDTEFFYWRELVSKCLAEYSS 257
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 106 bits (265), Expect = 3e-23
Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 7/210 (3%)
Query: 45 RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
RD ++ L L F ETF+LA +LLDRFL+ +K PK+L C+ +SCF+LA K++EE
Sbjct: 52 RDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEE 111
Query: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQ 164
+ +P+ L R S + S+++RME+I+L+K+ W + T FL +++++ P
Sbjct: 112 ERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPL 171
Query: 165 LLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIE 224
+ S + L QL C + + S+LAL++++LE++ L+ IE
Sbjct: 172 ------ERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE 225
Query: 225 LLQK-AQMDSSQLIHCRELVAHHLSTLQSS 253
LQK ++++ L +ELV+ L+ S+
Sbjct: 226 CLQKHSKINGRDLTFWQELVSKCLTEYSSN 255
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 106 bits (265), Expect = 3e-23
Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 7/210 (3%)
Query: 45 RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
RD ++ L L F ETF+LA +LLDRFL+ +K PK+L C+ +SCF+LA K++EE
Sbjct: 52 RDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEE 111
Query: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQ 164
+ +P+ L R S + S+++RME+I+L+K+ W + T FL +++++ P
Sbjct: 112 ERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPL 171
Query: 165 LLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIE 224
+ S + L QL C + + S+LAL++++LE++ L+ IE
Sbjct: 172 ------ERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE 225
Query: 225 LLQK-AQMDSSQLIHCRELVAHHLSTLQSS 253
LQK ++++ L +ELV+ L+ S+
Sbjct: 226 CLQKHSKINGRDLTFWQELVSKCLTEYSSN 255
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 73.9 bits (180), Expect = 2e-13
Identities = 63/224 (28%), Positives = 112/224 (50%), Gaps = 20/224 (8%)
Query: 37 NQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVK-AHPKYLSCIAISCF 95
+ ++ P R ++ WL ++ + L+ ETF LA DRF+ T K + L I I+
Sbjct: 134 HSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSL 193
Query: 96 FLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFH 155
F+A+K E+ P L+ A + CS +ILRME IIL L W+L T + +L++F
Sbjct: 194 FIASKL--EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL 251
Query: 156 AI-AVSTRPQLLFSLPKLSPSQHLAVLTKQLLH-CMACNQLLQFRGSMLALAMVSLEMEK 213
+ A+ P++L LP+ SQ + QLL C+ L+F+ +L A +
Sbjct: 252 QVDALKDAPKVL--LPQY--SQETFIQIAQLLDLCILAIDSLEFQYRILTAAALC----- 302
Query: 214 LIPDWLSLTIELLQKAQ-MDSSQLIHCRELVAHHLSTLQSSLPL 256
+IE+++KA ++ + C + + ++ ++S+ P+
Sbjct: 303 -----HFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPV 341
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 66.6 bits (161), Expect = 3e-11
Identities = 71/260 (27%), Positives = 120/260 (46%), Gaps = 33/260 (12%)
Query: 25 QMWKVNVRK----------MPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLD 74
++WK+ + K + + + P R ++ WL ++ + L+ ETF LA D
Sbjct: 115 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 174
Query: 75 RFLATVKAHPK-YLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERI 133
R++AT + K L I IS F+AAK E+ P L A + CS EIL ME +
Sbjct: 175 RYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELM 232
Query: 134 ILDKLNWDLHTATPLDFLHIFHAIA-VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACN 192
I+ L W L T + +L+++ +A ++ ++L LP+ P Q + + L C+
Sbjct: 233 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVL--LPQY-PQQIFIQIAELLDLCVLDV 289
Query: 193 QLLQFRGSMLALAMV----SLEMEKLIPDWLSLTIELLQK---------AQMDSSQLIHC 239
L+F +LA + + S E+ + + + IE K + SS+L H
Sbjct: 290 DCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHF 349
Query: 240 RELV---AHHLSTLQSSLPL 256
R + AH++ T + SL L
Sbjct: 350 RGVADEDAHNIQTHRDSLDL 369
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 66.6 bits (161), Expect = 3e-11
Identities = 71/260 (27%), Positives = 120/260 (46%), Gaps = 33/260 (12%)
Query: 25 QMWKVNVRK----------MPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLD 74
++WK+ + K + + + P R ++ WL ++ + L+ ETF LA D
Sbjct: 100 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 159
Query: 75 RFLATVKAHPK-YLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERI 133
R++AT + K L I IS F+AAK E+ P L A + CS EIL ME +
Sbjct: 160 RYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPPKLHQFAYVTDGACSGDEILTMELM 217
Query: 134 ILDKLNWDLHTATPLDFLHIFHAIA-VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACN 192
I+ L W L T + +L+++ +A ++ ++L LP+ P Q + + L C+
Sbjct: 218 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVL--LPQY-PQQIFIQIAELLDLCVLDV 274
Query: 193 QLLQFRGSMLALAMV----SLEMEKLIPDWLSLTIELLQK---------AQMDSSQLIHC 239
L+F +LA + + S E+ + + + IE K + SS+L H
Sbjct: 275 DCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHF 334
Query: 240 RELV---AHHLSTLQSSLPL 256
R + AH++ T + SL L
Sbjct: 335 RGVADEDAHNIQTHRDSLDL 354
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 62.0 bits (149), Expect = 8e-10
Identities = 45/128 (35%), Positives = 69/128 (53%), Gaps = 5/128 (3%)
Query: 40 VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAA 99
V+P R V+ WL ++ L +T LA LLD +L+ + L + ++C F+A
Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
Query: 100 KTVEEDERIPV-LKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIA 158
K E P L +L+ DSF S +E+LR ER IL +L++ LH PL L + A+A
Sbjct: 163 KMEECVLPEPAFLCLLSADSF---SRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALA 219
Query: 159 VSTRPQLL 166
S+ PQ++
Sbjct: 220 GSS-PQVM 226
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
Query: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
+++ P R V W+ ++ + E F LA + LDRFLA V +L + C FL
Sbjct: 49 KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108
Query: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156
A+K E + D+ E+L E ++L KL W+L TP DF+ HI
Sbjct: 109 ASKLKETSPLTAEKLCIYTDN--SIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRK 166
Query: 157 I 157
+
Sbjct: 167 L 167
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 58.5 bits (140), Expect = 9e-09
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 12/122 (9%)
Query: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
+ V PS R V W+ ++ + E F LA + LDRFL+ L + +C F+
Sbjct: 50 KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109
Query: 98 AAKTVEEDERIPVLKVLARDSFC-----GCSSSEILRMERIILDKLNWDLHTATPLDFLH 152
A+K E IP L + C E+L+ME ++++KL W+L TP DF+
Sbjct: 110 ASKM---KETIP----LTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIE 162
Query: 153 IF 154
F
Sbjct: 163 HF 164
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 19/175 (10%)
Query: 33 KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
K+PS + SP S R +A + +F L P LA LLD F+ + L +
Sbjct: 26 KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
Query: 91 AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
A+SC LA+K E+++ +P L+ L + GC + +L ME ++L+ W+L
Sbjct: 86 ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMAC 191
T F+ + + AV P + KL +++ + L AC
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQAAAC 197
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 24/204 (11%)
Query: 33 KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
K+PS + SP S R +A + +F L P LA LLD F+ + L +
Sbjct: 26 KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
Query: 91 AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
A+SC LA+K E+++ +P L+ L + GC + +L ME ++L+ W+L
Sbjct: 86 ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQ 196
T F+ + + AV P + KL +++ + L A L
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYA---FLN 199
Query: 197 FRGSMLALAMV--SLEMEKLIPDW 218
+ S++A A V S + +L P W
Sbjct: 200 YAPSLVAAACVASSRIILRLSPTW 223
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
Query: 33 KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
K+PS + SP S R +A + +F L P LA LLD F+ + L +
Sbjct: 26 KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
Query: 91 AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
A+SC LA+K E+++ +P L+ L + GC + +L ME ++L+ W+L
Sbjct: 86 ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 143 HTATPLDFLHIFHAIAV 159
T F+ + + AV
Sbjct: 143 CLPTAAHFIEYYLSEAV 159
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
++++ R ++ WL ++ +F L ET + ++DRFL K L + I+ L
Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218
Query: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
A+K E+ P ++ + +SS+I ME +IL +L ++L PL FL
Sbjct: 219 ASK--YEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFL 270
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 50.1 bits (118), Expect = 3e-06
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 28 KVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYL 87
K V M +++ S R ++ WL ++ ++ L ET LA + +DRFL+++ L
Sbjct: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253
Query: 88 SCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTAT 146
+ + LA+K E + + D++ + ++LRME ++L L +DL T
Sbjct: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY---TKKQVLRMEHLVLKVLTFDLAAPT 310
Query: 147 PLDFL 151
FL
Sbjct: 311 VNQFL 315
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 22 REAQMWKVNVRKMPSNQ-NVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
R+AQ + R+ + Q V+ R +++ WL + QF L E+ L + LDRFL T
Sbjct: 109 RKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTT 168
Query: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
+ ++ +A K VE R+ L L +F S ++ +E I+L KL+
Sbjct: 169 PVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAF---SRQQLCNLECIVLHKLH 225
Query: 140 WDLHTATPLDFL-HIFHA 156
+ L T FL H HA
Sbjct: 226 FTLGAPTISFFLEHFTHA 243
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 48.5 bits (114), Expect = 1e-05
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
+ V+ + R +I WL +++ +F L ET + S++DRF+ K L + ++ F+
Sbjct: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254
Query: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
A+K E+ P + A + + +I +ME IL LN+ L PL FL
Sbjct: 255 ASK--YEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 19/178 (10%)
Query: 40 VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAA 99
++ R ++ WL +++ F + ET LA L+D +L L + + F +AA
Sbjct: 1156 ITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAA 1215
Query: 100 KTVEEDE-RIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIA 158
K E + R+ + D++ SE+L ME IL+ L D++ FL + A
Sbjct: 1216 KFEEHNSPRVDDFVYICDDNY---QRSEVLSMEINILNVLKCDINIPIAYHFLRRY-ARC 1271
Query: 159 VSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALA--MVSLEMEKL 214
+ T ++ L+ S+++ +T Q H +Q + S LA A +++L M+KL
Sbjct: 1272 IHT------NMKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLLALYMKKL 1317
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 3/130 (2%)
Query: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
+ + P R + W+ ++ + E F LA + LDR+L+ V L + C L
Sbjct: 50 REIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLL 109
Query: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156
A+K + E + + K+ S ++ E ++L KL WDL DFL I H
Sbjct: 110 ASK-LRETTPLTIEKLCIYTDH-AVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHR 167
Query: 157 IAVSTRPQLL 166
+++ Q L
Sbjct: 168 LSLPRDRQAL 177
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235
Query: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
L + + LA+K E + + D++ + ++L+ME ++L L
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 292
Query: 140 WDLHTATPLDFL 151
+DL T FL
Sbjct: 293 FDLTVPTTNQFL 304
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ +
Sbjct: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235
Query: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
L + + LA+K E + + D++ + ++L+ME ++L L
Sbjct: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 292
Query: 140 WDLHTATPLDFL 151
+DL T FL
Sbjct: 293 FDLTVPTTNQFL 304
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ +
Sbjct: 219 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 278
Query: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
L + + LA+K E + + D++ + ++L+ME ++L L
Sbjct: 279 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 335
Query: 140 WDLHTATPLDFL 151
+DL T FL
Sbjct: 336 FDLTVPTTNQFL 347
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ +
Sbjct: 220 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 279
Query: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
L + + LA+K E + + D++ + ++L+ME ++L L
Sbjct: 280 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 336
Query: 140 WDLHTATPLDFL 151
+DL T FL
Sbjct: 337 FDLTVPTTNQFL 348
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 40.0 bits (92), Expect = 0.003
Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 23/187 (12%)
Query: 35 PSNQNVSPSQRDEVIQWLAKLK----YQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
PS+ SPS ++ + + F + ET LA L+D +L L +
Sbjct: 43 PSSLQESPSSLQGALKKRSAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLL 102
Query: 91 AISCFFLAAKTVEEDE-RIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
+ F +AAK E + R+ + D++ SE+L ME IL+ L D++
Sbjct: 103 GATAFMIAAKFEEHNSPRVDDFVYICDDNY---QRSEVLSMEINILNVLKCDINIPIAYH 159
Query: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALA--MV 207
FL + A + T ++ L+ S+++ +T Q H +Q + S LA A ++
Sbjct: 160 FLRRY-ARCIHT------NMKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLL 206
Query: 208 SLEMEKL 214
+L M+KL
Sbjct: 207 ALYMKKL 213
>gi|73760401 thymopoietin isoform gamma [Homo sapiens]
Length = 345
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)
Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
ELVA+++ TL + VYV L+H L ++ +S PDFS D + PV
Sbjct: 19 ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76
Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
G+ AA AA G K T K + + DD + L NED + + N G +
Sbjct: 77 LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134
Query: 354 CGT 356
GT
Sbjct: 135 VGT 137
>gi|73760405 thymopoietin isoform beta [Homo sapiens]
Length = 454
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)
Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
ELVA+++ TL + VYV L+H L ++ +S PDFS D + PV
Sbjct: 19 ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76
Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
G+ AA AA G K T K + + DD + L NED + + N G +
Sbjct: 77 LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134
Query: 354 CGT 356
GT
Sbjct: 135 VGT 137
>gi|4507555 thymopoietin isoform alpha [Homo sapiens]
Length = 694
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 11/123 (8%)
Query: 241 ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV 300
ELVA+++ TL + VYV L+H L ++ +S PDFS D + PV
Sbjct: 19 ELVANNV-TLPAGEQRKDVYVQLYLQH-LTARNRPPLPAGTNSKGPPDFSSDEEREPTPV 76
Query: 301 RGT-AAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSE------NVGSV 353
G+ AA AA G K T K + + DD + L NED + + N G +
Sbjct: 77 LGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDL--DVTELTNEDLLDQLVKYGVNPGPI 134
Query: 354 CGT 356
GT
Sbjct: 135 VGT 137
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 35.0 bits (79), Expect = 0.11
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 73 LDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMER 132
LDR+L+ V L + C LA+K + E + + K+ S ++ E
Sbjct: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASK-LRETTPLTIEKLCIYTDHA-VSPRQLRDWEV 61
Query: 133 IILDKLNWDLHTATPLDFL-HIFHAIAVSTRPQLL 166
++L KL WDL DFL I H +++ Q L
Sbjct: 62 LVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL 96
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 34.3 bits (77), Expect = 0.19
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 45 RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLA--TVKAHPKYLSCIAISCFFLAAKTV 102
R E +++ + + L+ +T A RF + K P+Y++ C FLA K
Sbjct: 50 RREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVT--GACCLFLAGKVE 107
Query: 103 EEDERIPVLKVLARD--------SFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
E ++ + AR F E++ +ERI+L + +DL P FL
Sbjct: 108 ETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFL 164
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,952,793
Number of Sequences: 37866
Number of extensions: 657534
Number of successful extensions: 1636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1593
Number of HSP's gapped (non-prelim): 37
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.