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Search of human proteins with 5730019
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5730019 peropsin [Homo sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5730019 peropsin [Homo sapiens] 689 0.0
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 172 5e-43
gi|38678524 opsin 5 isoform 1 [Homo sapiens] 167 9e-42
gi|71999131 opsin 3 [Homo sapiens] 167 2e-41
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 164 1e-40
gi|4506527 rhodopsin [Homo sapiens] 159 4e-39
gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 144 9e-35
gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 144 9e-35
gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 142 4e-34
gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 132 3e-31
gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 128 8e-30
gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 113 2e-25
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 112 4e-25
gi|157426873 tachykinin receptor 2 [Homo sapiens] 109 3e-24
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 107 2e-23
gi|7669548 tachykinin receptor 3 [Homo sapiens] 106 3e-23
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 104 1e-22
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 102 4e-22
gi|4557859 somatostatin receptor 2 [Homo sapiens] 100 3e-21
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 94 1e-19
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 94 2e-19
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 94 2e-19
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 94 2e-19
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 94 2e-19
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 94 2e-19
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 94 2e-19
gi|5174593 melatonin receptor 1A [Homo sapiens] 94 2e-19
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 94 2e-19
gi|71999146 opsin 5 isoform 2 [Homo sapiens] 93 3e-19
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 92 7e-19
>gi|5730019 peropsin [Homo sapiens]
Length = 337
Score = 689 bits (1778), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT 60
MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT
Sbjct: 1 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT 60
Query: 61 NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA 120
NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA
Sbjct: 61 NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA 120
Query: 121 VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR 180
VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR
Sbjct: 121 VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR 180
Query: 181 KNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTK 240
KNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTK
Sbjct: 181 KNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTK 240
Query: 241 MSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKK 300
MSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKK
Sbjct: 241 MSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKK 300
Query: 301 FRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI 337
FRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
Sbjct: 301 FRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI 337
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 172 bits (435), Expect = 5e-43
Identities = 92/298 (30%), Positives = 155/298 (52%), Gaps = 11/298 (3%)
Query: 25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAA 84
H + T +++ G+ ++ N+ V+ F + + LRTP N IINLAV+D +S P+
Sbjct: 70 HYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFT 129
Query: 85 SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIG- 143
S LY W FG GC+ YA FG++S+ LT +A+DRYL I P + +
Sbjct: 130 SSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAF 189
Query: 144 LILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLT 203
++LG W+ L W+L P GW++Y P+ +C+ ++ + +YTM + F +PL
Sbjct: 190 VLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLL 249
Query: 204 VMFYCYYHVTLSIKH-----HTTSDCTESLNRDWSDQ-----IDVTKMSVIMICMFLVAW 253
++ YCY + +I+ T C + W Q + K+ +++I +F+++W
Sbjct: 250 IIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSW 309
Query: 254 SPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKC 311
+PYS V L A G + P M+ + + AK+S +NP IY + + K+R A+ C
Sbjct: 310 APYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPC 367
>gi|38678524 opsin 5 isoform 1 [Homo sapiens]
Length = 354
Score = 167 bits (424), Expect = 9e-42
Identities = 90/294 (30%), Positives = 152/294 (51%), Gaps = 8/294 (2%)
Query: 16 DGSVFSQT---EHNIVAT-YLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTD 71
DG F+ E ++VA YL + G++S N VL + + K+ P + INLAV D
Sbjct: 20 DGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCD 79
Query: 72 IGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPD 131
+G+S +G P + S W FG+ GC+ Y FFG S+ +T V++DRYL IC
Sbjct: 80 LGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLS 139
Query: 132 VGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVS--Y 189
G + + W FW MP++G Y P+P G +CT++W S +
Sbjct: 140 YGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVF 199
Query: 190 TMTVIAINFIVPLTVMFYCYYHVTLSIKHHT--TSDCTESLNRDWSDQIDVTKMSVIMIC 247
+ ++ ++P V+ + Y + +K + + ++ ++ +TK+++++
Sbjct: 200 ILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICA 259
Query: 248 MFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKF 301
FL+AW PY++V +W++FG P IP ++++ L AKS+ YNP IY V + KF
Sbjct: 260 GFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
>gi|71999131 opsin 3 [Homo sapiens]
Length = 402
Score = 167 bits (422), Expect = 2e-41
Identities = 96/296 (32%), Positives = 158/296 (53%), Gaps = 13/296 (4%)
Query: 19 VFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIG 78
+FS + +A L G++ + +N++VL ++ K++ LRTPT+ +++N++++D+ VS G
Sbjct: 35 LFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFG 94
Query: 79 YPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTT 138
+ S L W + GC FG+ SI LTV+A +RY+ + V R+
Sbjct: 95 VTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRV----VHARVIN 150
Query: 139 NTYIG-LILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAIN 197
++ I W+ L WA P++GW Y D G CT++W+ D + S+ + +
Sbjct: 151 FSWAWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGC 210
Query: 198 FIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQI-----DVTKMSVIMICMFLVA 252
+VPL V+ +CY H+ SI+ C E L +I + KM +MI FLV
Sbjct: 211 LVVPLGVIAHCYGHILYSIR---MLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVC 267
Query: 253 WSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAM 308
W PY ++C G + P ++I++ LFAKS+T YNP IYV +KFRR++L +
Sbjct: 268 WMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 164 bits (414), Expect = 1e-40
Identities = 92/309 (29%), Positives = 156/309 (50%), Gaps = 22/309 (7%)
Query: 25 HNIVATYLIMAGMISIISNIIVLGIF-----------IKYKELRTPTNAIIINLAVTDIG 73
H + T +++ G+ ++ N+ V+ F ++ + LRTP N IINLAV+D
Sbjct: 70 HYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
Query: 74 VSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVG 133
+S P+ S LY W FG GC+ YA FG++S+ LT +A+DRYL I P
Sbjct: 130 MSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLAT 189
Query: 134 RRMTTNTYIG-LILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMT 192
+ + ++LG W+ L W+L P GW++Y P+ +C+ ++ + +YTM
Sbjct: 190 FGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTML 249
Query: 193 VIAINFIVPLTVMFYCYYHVTLSIKH-----HTTSDCTESLNRDWSDQ-----IDVTKMS 242
+ F +PL ++ YCY + +I+ T C + W Q + K+
Sbjct: 250 LCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIM 309
Query: 243 VIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFR 302
+++I +F+++W+PYS V L A G + P M+ + + AK+S +NP IY + + K+R
Sbjct: 310 LLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 369
Query: 303 RAMLAMFKC 311
A+ C
Sbjct: 370 VAIAQHLPC 378
>gi|4506527 rhodopsin [Homo sapiens]
Length = 348
Score = 159 bits (401), Expect = 4e-39
Identities = 86/293 (29%), Positives = 152/293 (51%), Gaps = 10/293 (3%)
Query: 24 EHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSA 83
+ +++A Y+ + ++ N + L + +++K+LRTP N I++NLAV D+ + G+ +
Sbjct: 36 QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTL 95
Query: 84 ASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIG 143
+ L+G + FG GC + G ++ L V+A++RY+ +C P R N I
Sbjct: 96 YTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIM 155
Query: 144 LILGAWINGLFWALMPIIGWASYAPDPTGATCTINW-----RKNDRSFVSYTMTVIAINF 198
+ W+ L A P+ GW+ Y P+ +C I++ N+ SFV Y + ++F
Sbjct: 156 GVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIY---MFVVHF 212
Query: 199 IVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSI 258
+P+ ++F+CY + ++K + ES +++ +VT+M +IM+ FL+ W PY+
Sbjct: 213 TIPMIIIFFCYGQLVFTVK-EAAAQQQESATTQKAEK-EVTRMVIIMVIAFLICWVPYAS 270
Query: 259 VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKC 311
V + P I FAKS+ YNP IY++ NK+FR ML C
Sbjct: 271 VAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICC 323
>gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo
sapiens]
Length = 364
Score = 144 bits (364), Expect = 9e-35
Identities = 86/310 (27%), Positives = 150/310 (48%), Gaps = 12/310 (3%)
Query: 25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAA 84
+++ + ++I + S+ +N +VL +K+K+LR P N I++NLAV D+ + I +S
Sbjct: 53 YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVV 112
Query: 85 SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGL 144
+ +YG + G+ C + G+ + L +++ +R++ +C P R I
Sbjct: 113 NQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVG 172
Query: 145 ILGAWINGLFWALMPIIGWASYAPDPTGATC--TINWRKNDRSFVSYTMTVIAINFIVPL 202
I +WI W PI GW+ Y P +C + + SY + ++ I PL
Sbjct: 173 IAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPL 232
Query: 203 TVMFYCYYHVTLSI----KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSI 258
+++ CY V L+I K S+ T+ + +VT+M V+M+ F W PY+
Sbjct: 233 SIIVLCYLQVWLAIRAVAKQQKESESTQKAEK------EVTRMVVVMVLAFCFCWGPYAF 286
Query: 259 VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMP 318
+A+ P MA + FAKS+T YNP IYV N++FR +L +F +
Sbjct: 287 FACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSE 346
Query: 319 VTSILPMDVS 328
++S +VS
Sbjct: 347 LSSASKTEVS 356
>gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo
sapiens]
Length = 364
Score = 144 bits (364), Expect = 9e-35
Identities = 86/310 (27%), Positives = 150/310 (48%), Gaps = 12/310 (3%)
Query: 25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAA 84
+++ + ++I + S+ +N +VL +K+K+LR P N I++NLAV D+ + I +S
Sbjct: 53 YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVV 112
Query: 85 SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGL 144
+ +YG + G+ C + G+ + L +++ +R++ +C P R I
Sbjct: 113 NQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVG 172
Query: 145 ILGAWINGLFWALMPIIGWASYAPDPTGATC--TINWRKNDRSFVSYTMTVIAINFIVPL 202
I +WI W PI GW+ Y P +C + + SY + ++ I PL
Sbjct: 173 IAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPL 232
Query: 203 TVMFYCYYHVTLSI----KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSI 258
+++ CY V L+I K S+ T+ + +VT+M V+M+ F W PY+
Sbjct: 233 SIIVLCYLQVWLAIRAVAKQQKESESTQKAEK------EVTRMVVVMVLAFCFCWGPYAF 286
Query: 259 VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMP 318
+A+ P MA + FAKS+T YNP IYV N++FR +L +F +
Sbjct: 287 FACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSE 346
Query: 319 VTSILPMDVS 328
++S +VS
Sbjct: 347 LSSASKTEVS 356
>gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo
sapiens]
Length = 364
Score = 142 bits (358), Expect = 4e-34
Identities = 87/310 (28%), Positives = 149/310 (48%), Gaps = 12/310 (3%)
Query: 25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAA 84
+++ + ++I S+ +N +VL +K+K+LR P N I++NLAV D+ + I +S
Sbjct: 53 YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIV 112
Query: 85 SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGL 144
+ + G + G+ C + G+ + L +++ +R+L +C P R I
Sbjct: 113 NQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVG 172
Query: 145 ILGAWINGLFWALMPIIGWASYAPDPTGATC--TINWRKNDRSFVSYTMTVIAINFIVPL 202
I +WI W PI GW+ Y P +C + + SY + ++ I+PL
Sbjct: 173 IAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPL 232
Query: 203 TVMFYCYYHVTLSI----KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSI 258
++ CY V L+I K S+ T+ + +VT+M V+MI + V W PY+
Sbjct: 233 AIIMLCYLQVWLAIRAVAKQQKESESTQKAEK------EVTRMVVVMIFAYCVCWGPYTF 286
Query: 259 VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMP 318
+A+ P MA + FAKS+T YNP IYV N++FR +L +F +
Sbjct: 287 FACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSE 346
Query: 319 VTSILPMDVS 328
++S +VS
Sbjct: 347 LSSASKTEVS 356
>gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
sapiens]
Length = 291
Score = 132 bits (333), Expect = 3e-31
Identities = 79/286 (27%), Positives = 134/286 (46%), Gaps = 20/286 (6%)
Query: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
F + E V L++ + + N + + F K ELRTP + ++++LA+ D G+S +
Sbjct: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNA 69
Query: 80 PMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTN 139
++A S L W +G GCQ + +ASI +A RY C ++ N
Sbjct: 70 LVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS---QLAWN 126
Query: 140 TYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFI 199
+ + L+L W++ FWA +P++GW Y +P G CT+++ K DR+F S+ T+ NF
Sbjct: 127 SAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFA 186
Query: 200 VPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIV 259
+PL + Y S + L + Q++ T + L+ W PY+I+
Sbjct: 187 MPLFITITSY------------SLMEQKLGKSGHLQVNTT----LPARTLLLGWGPYAIL 230
Query: 260 CLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAM 305
L+A D I P + ++ L AK N Y + N+ R +
Sbjct: 231 YLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGI 276
>gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
sapiens]
Length = 295
Score = 128 bits (321), Expect = 8e-30
Identities = 79/290 (27%), Positives = 135/290 (46%), Gaps = 24/290 (8%)
Query: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
F + E V L++ + + N + + F K ELRTP + ++++LA+ D G+S +
Sbjct: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNA 69
Query: 80 PMSAASDL----YGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRR 135
++A S L + W +G GCQ + +ASI +A RY C +
Sbjct: 70 LVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS---Q 126
Query: 136 MTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIA 195
+ N+ + L+L W++ FWA +P++GW Y +P G CT+++ K DR+F S+ T+
Sbjct: 127 LAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSF 186
Query: 196 INFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSP 255
NF +PL + Y S + L + Q++ T + L+ W P
Sbjct: 187 FNFAMPLFITITSY------------SLMEQKLGKSGHLQVNTT----LPARTLLLGWGP 230
Query: 256 YSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAM 305
Y+I+ L+A D I P + ++ L AK N Y + N+ R +
Sbjct: 231 YAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGI 280
>gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo
sapiens]
Length = 253
Score = 113 bits (283), Expect = 2e-25
Identities = 58/190 (30%), Positives = 98/190 (51%), Gaps = 4/190 (2%)
Query: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
F + E V L++ + + N + + F K ELRTP + ++++LA+ D G+S +
Sbjct: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNA 69
Query: 80 PMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTN 139
++A S L W +G GCQ + +ASI +A RY C ++ N
Sbjct: 70 LVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS---QLAWN 126
Query: 140 TYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFI 199
+ + L+L W++ FWA +P++GW Y +P G CT+++ K DR+F S+ T+ NF
Sbjct: 127 SAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFA 186
Query: 200 VPLTVMFYCY 209
+PL + Y
Sbjct: 187 MPLFITITSY 196
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 112 bits (281), Expect = 4e-25
Identities = 81/317 (25%), Positives = 144/317 (45%), Gaps = 12/317 (3%)
Query: 4 NNLGNSSDSKNEDGSVFSQTEHNIV---ATYLIMAGMISIISNIIVLGIFIKYKELRTPT 60
++L + + + + F Q IV A Y ++ + S++ N++V+ I + +K +RT T
Sbjct: 9 SDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIV-VTSVVGNVVVMWIILAHKRMRTVT 67
Query: 61 NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA 120
N ++NLA + +++ ++ ++ W +G C+ + I ASI +T VA
Sbjct: 68 NYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVA 127
Query: 121 VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR 180
DRY+ I P R T T + +I W+ L A P +++ P+ C I W
Sbjct: 128 FDRYMAIIHPLQPRLSATATKV-VICVIWVLALLLA-FPQGYYSTTETMPSRVVCMIEWP 185
Query: 181 KNDRSFVS--YTMTVIAINFIVPLTVMFYCYYHVTLSI-KHHTTSDCTESLNRDWSDQID 237
++ Y + V + + +PL V+ Y Y V +++ D ++ + S +
Sbjct: 186 EHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRK 245
Query: 238 VTKMSVIMICMFLVAWSPYSIVCLWASFGDP---KKIPPPMAIIAPLFAKSSTFYNPCIY 294
V KM ++++C F + W P+ I L KK + + A SST YNP IY
Sbjct: 246 VVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305
Query: 295 VVANKKFRRAMLAMFKC 311
N +FR F+C
Sbjct: 306 CCLNDRFRLGFKHAFRC 322
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 109 bits (273), Expect = 3e-24
Identities = 81/316 (25%), Positives = 138/316 (43%), Gaps = 11/316 (3%)
Query: 5 NLGNSSDSKNEDGSVFSQTEHNIV--ATYLIMAGMISIISNIIVLGIFIKYKELRTPTNA 62
N+ + +S + FS + AT + ++++ N IV+ I + ++ +RT TN
Sbjct: 11 NISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNY 70
Query: 63 IIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVD 122
I+NLA+ D+ +++ + + W FG A C I SI +T +A D
Sbjct: 71 FIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAAD 130
Query: 123 RYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKN 182
RY+ I P R +T +I G W+ L A P +++ D C + W ++
Sbjct: 131 RYMAIVHPFQPRLSAPSTK-AVIAGIWLVALALA-SPQCFYSTVTMDQGATKCVVAWPED 188
Query: 183 D--RSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSI-KHHTTSDCTESLN-RDWSDQIDV 238
++ + Y + VIA+ + +PL VMF Y + L++ + N R
Sbjct: 189 SGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKF 248
Query: 239 TKMSVIMICMFLVAWSPYSIVCLWASFGDP---KKIPPPMAIIAPLFAKSSTFYNPCIYV 295
K V+++ F + W PY + + SF + K + + A SST YNP IY
Sbjct: 249 VKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYC 308
Query: 296 VANKKFRRAMLAMFKC 311
N +FR F+C
Sbjct: 309 CLNHRFRSGFRLAFRC 324
>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
sapiens]
Length = 348
Score = 107 bits (266), Expect = 2e-23
Identities = 72/283 (25%), Positives = 136/283 (48%), Gaps = 6/283 (2%)
Query: 29 ATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIG-YPMSAASDL 87
A ++ +I N +VL ++YK+LR P N I++N++ + +P+ AS
Sbjct: 38 AAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVAS-C 96
Query: 88 YGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILG 147
G + FG C + L G+ + L +A +RY+ IC P R ++ + ++L
Sbjct: 97 NGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLA 156
Query: 148 AWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSF--VSYTMTVIAINFIVPLTVM 205
W G+ ++ P GW+ + P+ +C +W + SYT + FIVPL+++
Sbjct: 157 TWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLI 216
Query: 206 FYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASF 265
+ Y + ++K + ES +++ +V++M V+M+ F V + PY+ ++
Sbjct: 217 CFSYTQLLRALK-AVAAQQQESATTQKAER-EVSRMVVVMVGSFCVCYVPYAAFAMYMVN 274
Query: 266 GDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAM 308
+ + I F+KS+ YNP IY NK+F+ ++ M
Sbjct: 275 NRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKM 317
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 106 bits (265), Expect = 3e-23
Identities = 75/277 (27%), Positives = 125/277 (45%), Gaps = 6/277 (2%)
Query: 38 ISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAG 97
++++ N+IV+ I + +K +RT TN ++NLA +D +++ ++ L+ W FG
Sbjct: 98 VAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANY 157
Query: 98 CQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWAL 157
C+ I ASI +T +AVDRY+ I P R T T I +I WI F
Sbjct: 158 CRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKI-VIGSIWILA-FLLA 215
Query: 158 MPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSI- 216
P ++ P C + W + + +Y + VI + + PL +M Y V +++
Sbjct: 216 FPQCLYSKTKVMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLW 275
Query: 217 KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPK---KIPP 273
D + + + V KM +I++ F + W PY I + + K
Sbjct: 276 GGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQ 335
Query: 274 PMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFK 310
+ + + A SST YNP IY NK+FR F+
Sbjct: 336 QVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFR 372
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 104 bits (260), Expect = 1e-22
Identities = 77/306 (25%), Positives = 139/306 (45%), Gaps = 12/306 (3%)
Query: 4 NNLGNSSDSKNEDGSVFSQTEHNIV---ATYLIMAGMISIISNIIVLGIFIKYKELRTPT 60
++L + + + + F Q IV A Y ++ + S++ N++V+ I + +K +RT T
Sbjct: 9 SDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIV-VTSVVGNVVVMWIILAHKRMRTVT 67
Query: 61 NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA 120
N ++NLA + +++ ++ ++ W +G C+ + I ASI +T VA
Sbjct: 68 NYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVA 127
Query: 121 VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR 180
DRY+ I P R T T + +I W+ L A P +++ P+ C I W
Sbjct: 128 FDRYMAIIHPLQPRLSATATKV-VICVIWVLALLLA-FPQGYYSTTETMPSRVVCMIEWP 185
Query: 181 KNDRSFVS--YTMTVIAINFIVPLTVMFYCYYHVTLSI-KHHTTSDCTESLNRDWSDQID 237
++ Y + V + + +PL V+ Y Y V +++ D ++ + S +
Sbjct: 186 EHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRK 245
Query: 238 VTKMSVIMICMFLVAWSPYSIVCLWASFGDP---KKIPPPMAIIAPLFAKSSTFYNPCIY 294
V KM ++++C F + W P+ I L KK + + A SST YNP IY
Sbjct: 246 VVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305
Query: 295 VVANKK 300
N +
Sbjct: 306 CCLNDR 311
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 102 bits (255), Expect = 4e-22
Identities = 76/291 (26%), Positives = 128/291 (43%), Gaps = 24/291 (8%)
Query: 37 MISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYA 96
++ +I N +V+ + IK+K +RT TN I NLAV D+ V+++ P + L G WK G
Sbjct: 62 LLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPV 121
Query: 97 GCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWA 156
C + S LTV+A+DR+ I + I + I GL W
Sbjct: 122 LCHLVPYAQGLAVQVSTITLTVIALDRHRCIV-------YHLESKISKRISFLIIGLAWG 174
Query: 157 L-----MPIIGWASYA-----PDPTGATCTINWRKNDRSFVS--YTMTVIAINFIVPLTV 204
+ P+ + Y+ PD CT W ++S Y+++ + I +++PL +
Sbjct: 175 ISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGI 234
Query: 205 MFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWAS 264
+ + Y + +K+H + + TKM V ++ +F V+W P L
Sbjct: 235 ISFSYTRIWSKLKNHVSPGAANDHYHQRRQK--TTKMLVCVVVVFAVSWLPLHAFQLAVD 292
Query: 265 FGDPKKIPPPMAIIAPLF---AKSSTFYNPCIYVVANKKFRRAMLAMFKCQ 312
+I +F A STF NP +Y N +R+A L+ F+C+
Sbjct: 293 IDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCE 343
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 99.8 bits (247), Expect = 3e-21
Identities = 69/300 (23%), Positives = 140/300 (46%), Gaps = 8/300 (2%)
Query: 9 SSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLA 68
S+++ N+ + T + ++ + +I + N +V+ + ++Y +++T TN I+NLA
Sbjct: 27 STNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLA 86
Query: 69 VTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTIC 128
+ D + +G P A W FG A C+V ++ SI LTV+++DRYL +
Sbjct: 87 IAD-ELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVV 145
Query: 129 LPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTG-ATCTINW-RKNDRSF 186
P + +I A ++PI+ +A + G ++CTINW ++ +
Sbjct: 146 HPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWY 205
Query: 187 VSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMI 246
+ + + F+VPLT++ CY + + +K +S ++ + VT+M I++
Sbjct: 206 TGFIIYTFILGFLVPLTIICLCYLFIIIKVK---SSGIRVGSSKRKKSEKKVTRMVSIVV 262
Query: 247 CMFLVAWSPYSI--VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRA 304
+F+ W P+ I V + P M + +++ NP +Y + F+++
Sbjct: 263 AVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKS 322
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 94.4 bits (233), Expect = 1e-19
Identities = 73/313 (23%), Positives = 139/313 (44%), Gaps = 25/313 (7%)
Query: 4 NNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAI 63
N S D++ E + I A Y ++ ++ ++ N +V+ + I+Y +++T TN
Sbjct: 39 NGSAGSEDAQLEPAHISPAIPVIITAVYSVVF-VVGLVGNSLVMFVIIRYTKMKTATNIY 97
Query: 64 IINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDR 123
I NLA+ D V++ P + L SW FG C++ ++ + SI LT+++VDR
Sbjct: 98 IFNLALADALVTTT-MPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDR 156
Query: 124 YLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMP-------IIGWASYAPDPTGATCT 176
Y+ +C P T + IN W L ++G D C+
Sbjct: 157 YIAVCHPVKALDFRTP-----LKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECS 211
Query: 177 INWRKNDRSFVSYTM--TVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSD 234
+ + +D S+ M V F++P+ ++ CY + L +K + +R+
Sbjct: 212 LQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLR- 270
Query: 235 QIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMA----IIAPLFAKSSTFYN 290
+T++ ++++ +F+V W+P I L + G ++ IA + SS N
Sbjct: 271 --RITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSS--LN 326
Query: 291 PCIYVVANKKFRR 303
P +Y ++ F+R
Sbjct: 327 PILYAFLDENFKR 339
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 94.0 bits (232), Expect = 2e-19
Identities = 84/324 (25%), Positives = 138/324 (42%), Gaps = 30/324 (9%)
Query: 14 NEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRT-PTNAIIINLAVTDI 72
+E+G F E ++ T+L +++I+ N++V+ ++LR TN I++LA D+
Sbjct: 10 SEEG--FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADL 67
Query: 73 GVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICL-PD 131
VS + P A + W +G C V L++ ASI L +++DRY IC P
Sbjct: 68 LVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPL 127
Query: 132 VGRRMTTNTYIGLIL-GAWINGLFWALMPII-GWASYAPDPTGATCTINWRKNDRSFV-- 187
V R T I L+L G W+ F + +PI+ GW + N N V
Sbjct: 128 VYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFM 187
Query: 188 ---SYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHT-----------------TSDCTES 227
Y +T + F +P +M YY + ++ K H S S
Sbjct: 188 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 247
Query: 228 LNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSST 287
+R ++ + +IM C F + W+P+ + + F D +P + ++
Sbjct: 248 THRMRTETKAAKTLCIIMGC-FCLCWAPFFVTNIVDPFID-YTVPGQVWTAFLWLGYINS 305
Query: 288 FYNPCIYVVANKKFRRAMLAMFKC 311
NP +Y NK FRRA L + C
Sbjct: 306 GLNPFLYAFLNKSFRRAFLIILCC 329
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 94.0 bits (232), Expect = 2e-19
Identities = 72/284 (25%), Positives = 133/284 (46%), Gaps = 17/284 (5%)
Query: 28 VATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDL 87
+A LI ++ I+ N++V+ + K+LR N +++LAV D+ V+ YP+ S
Sbjct: 30 LACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIF 89
Query: 88 YGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLP-DVGRRMTTNTYIGLIL 146
W GY CQV L + SI +T +A++RY IC + ++ + +L
Sbjct: 90 NNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVL 149
Query: 147 GAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMF 206
W+ L A++P + + DP +CT + +YT+ V+ +F+VP+ ++
Sbjct: 150 LIWLLTLA-AVLPNLRAGTLQYDPRIYSCTFAQSVSS----AYTIAVVVFHFLVPMIIVI 204
Query: 207 YCYYHV---TLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWA 263
+CY + L ++ D L D + M V+ + +F + W+P + + L A
Sbjct: 205 FCYLRIWILVLQVRQRVKPDRKPKLKP--QDFRNFVTMFVVFV-LFAICWAPLNFIGL-A 260
Query: 264 SFGDP----KKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRR 303
DP +IP + + + A ++ N IY + N+ FR+
Sbjct: 261 VASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRK 304
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 94.0 bits (232), Expect = 2e-19
Identities = 71/289 (24%), Positives = 136/289 (47%), Gaps = 15/289 (5%)
Query: 32 LIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSW 91
+++ ++ +I N +V+ K K+LR N +++L+V D+ V+ YP+ + G W
Sbjct: 35 MVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGW 94
Query: 92 KFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRM--TTNTYIGLILGAW 149
CQ+ + + SI + +A++RY IC R+ NT I L++ W
Sbjct: 95 DLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVI-TW 153
Query: 150 INGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCY 209
I + A++P + + DP TC N+ N +T+T++ I+F++PL ++ +CY
Sbjct: 154 IMTVL-AVLPNMYIGTIEYDPRTYTCIFNYLNNP----VFTVTIVCIHFVLPLLIVGFCY 208
Query: 210 YHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPK 269
+ + ++ + ++ + M VI + +F V W P +++ + + PK
Sbjct: 209 VRIWTKVL-AARDPAGQNPDNQLAEVRNFLTMFVIFL-LFAVCWCPINVLTVLVAV-SPK 265
Query: 270 ----KIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTH 314
KIP + + A A ++ N IY + N+ FRR +F H
Sbjct: 266 EMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRH 314
>gi|71999146 opsin 5 isoform 2 [Homo sapiens]
Length = 189
Score = 93.2 bits (230), Expect = 3e-19
Identities = 42/148 (28%), Positives = 82/148 (55%), Gaps = 4/148 (2%)
Query: 158 MPIIGWASYAPDPTGATCTINWRKNDRSFVS--YTMTVIAINFIVPLTVMFYCYYHVTLS 215
MP++G Y P+P G +CT++W S + + ++ ++P V+ + Y +
Sbjct: 1 MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK 60
Query: 216 IKHHT--TSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPP 273
+K + + ++ ++ +TK+++++ FL+AW PY++V +W++FG P IP
Sbjct: 61 VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 120
Query: 274 PMAIIAPLFAKSSTFYNPCIYVVANKKF 301
++++ L AKS+ YNP IY V + KF
Sbjct: 121 QLSVVPTLLAKSAAMYNPIIYQVIDYKF 148
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 92.0 bits (227), Expect = 7e-19
Identities = 56/195 (28%), Positives = 96/195 (49%), Gaps = 10/195 (5%)
Query: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
+ + E ++ + L + +++I N +V+ K+LR P+N +I++LA+ D+ V+
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVM 135
Query: 80 PMSAASDLY-GSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLP-DVGRRMT 137
P + +DL G W FG+ C V+ +++ ASI L V+++DRYL I P R
Sbjct: 136 PFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN 195
Query: 138 TNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAIN 197
+IL W+ L P+ GWA D C I+ YT+ A+
Sbjct: 196 GKCMAKMILSVWLLSASITLPPLFGWAQNVND--DKVCLIS------QDFGYTIYSTAVA 247
Query: 198 FIVPLTVMFYCYYHV 212
F +P++VM + YY +
Sbjct: 248 FYIPMSVMLFMYYQI 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,002,916
Number of Sequences: 37866
Number of extensions: 476811
Number of successful extensions: 2887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 518
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 1514
Number of HSP's gapped (non-prelim): 940
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.