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Search of human proteins with 57242796
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57242796 jumonji, AT rich interactive domain 1B [Homo
sapiens]
(1544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 3161 0.0
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 2023 0.0
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 1498 0.0
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 1498 0.0
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 1356 0.0
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 1318 0.0
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 1303 0.0
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 1221 0.0
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 1154 0.0
gi|98986459 jumonji domain containing 2A [Homo sapiens] 137 6e-32
gi|39653317 jumonji domain containing 2D [Homo sapiens] 137 8e-32
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ... 134 7e-31
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 133 1e-30
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens] 133 1e-30
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens] 133 1e-30
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens] 133 1e-30
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 133 1e-30
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 133 1e-30
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 133 1e-30
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 132 2e-30
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 132 2e-30
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 132 2e-30
gi|45504380 jumonji domain containing 2B [Homo sapiens] 132 3e-30
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 2e-13
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 73 2e-12
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 73 2e-12
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 68 8e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 67 2e-10
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 66 3e-10
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 65 4e-10
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 3161 bits (8195), Expect = 0.0
Identities = 1544/1544 (100%), Positives = 1544/1544 (100%)
Query: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG
Sbjct: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
Query: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI
Sbjct: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
Query: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN
Sbjct: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
Query: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN
Sbjct: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
Query: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS
Sbjct: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
Query: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE
Sbjct: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED
Sbjct: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC
Sbjct: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE
Sbjct: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV
Sbjct: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE
Sbjct: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK
Sbjct: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK
Sbjct: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN
Sbjct: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF
Sbjct: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR
Sbjct: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
Query: 961 LQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDW 1020
LQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDW
Sbjct: 961 LQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDW 1020
Query: 1021 LQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTE 1080
LQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTE
Sbjct: 1021 LQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTE 1080
Query: 1081 NSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETAS 1140
NSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETAS
Sbjct: 1081 NSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETAS 1140
Query: 1141 AMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFH 1200
AMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFH
Sbjct: 1141 AMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFH 1200
Query: 1201 TSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTV 1260
TSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTV
Sbjct: 1201 TSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTV 1260
Query: 1261 NWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWD 1320
NWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWD
Sbjct: 1261 NWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWD 1320
Query: 1321 NRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQT 1380
NRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQT
Sbjct: 1321 NRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQT 1380
Query: 1381 DRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKL 1440
DRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKL
Sbjct: 1381 DRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKL 1440
Query: 1441 SHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEV 1500
SHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEV
Sbjct: 1441 SHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEV 1500
Query: 1501 DWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK 1544
DWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK
Sbjct: 1501 DWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK 1544
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 2023 bits (5242), Expect = 0.0
Identities = 977/977 (100%), Positives = 977/977 (100%)
Query: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG
Sbjct: 1 MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTG 60
Query: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI
Sbjct: 61 ICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKI 120
Query: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN
Sbjct: 121 PHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILN 180
Query: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN
Sbjct: 181 PYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMN 240
Query: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS
Sbjct: 241 IKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRS 300
Query: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE
Sbjct: 301 KKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED
Sbjct: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC
Sbjct: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE
Sbjct: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV
Sbjct: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE
Sbjct: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK
Sbjct: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK
Sbjct: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN
Sbjct: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF
Sbjct: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR
Sbjct: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMAR 960
Query: 961 LQELLTVSEHWDDKAKS 977
LQELLTVSEHWDDKAKS
Sbjct: 961 LQELLTVSEHWDDKAKS 977
Score = 32.7 bits (73), Expect = 2.8
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 1174 VDIKICL-CQKAPAAP-MIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSE 1225
VD+ +CL C ++ C+ C D++HT C+ P W CP C E
Sbjct: 307 VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 1498 bits (3878), Expect = 0.0
Identities = 733/1276 (57%), Positives = 941/1276 (73%), Gaps = 24/1276 (1%)
Query: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
Query: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
Query: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
Query: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
Query: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
Query: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
Query: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
Query: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
Query: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
Query: 970 HWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQA 1029
W++KAK L+ARPRHS+ SL + V E + IPA+LPN +LK+++Q+AR+W VE +Q+
Sbjct: 954 RWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQS 1013
Query: 1030 GGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEV 1089
G L+ L L +GR IPV L +LP++E+ VA +AW+E TFL +NS ++LL+V
Sbjct: 1014 GSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQV 1073
Query: 1090 LCPRCDIGLLGL-KRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEA 1148
L PR DIG+ G K +++K+KE + K+K LE LSDLE L E+++TA +A E
Sbjct: 1074 LSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKER 1133
Query: 1149 RLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPS 1208
+E+EA+ SLR AN K+ + ++K C+C+K + M+QCELC+D FH SCV +P
Sbjct: 1134 EQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPK 1193
Query: 1209 ISQGLR---------IWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERT 1259
S + +LCP C RS +P LE IL LL SLQ++ VRLPEG+AL+ + ER
Sbjct: 1194 SSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERA 1253
Query: 1260 VNWQHRAQQLLSSGNL 1275
++WQ RA+Q L++ L
Sbjct: 1254 MSWQDRARQALATDEL 1269
Score = 149 bits (375), Expect = 3e-35
Identities = 89/228 (39%), Positives = 122/228 (53%), Gaps = 30/228 (13%)
Query: 1341 GVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKR 1400
G ++ EL+M LL+VSL E Q +++ L A P++ S E+ K
Sbjct: 1440 GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPL---KV 1496
Query: 1401 DGINSLERKLKRRLERE----GLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKL----- 1451
G +S E+K KR+LE+ G ++ + +KKM P+KKK+KL K KL
Sbjct: 1497 KGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLA 1556
Query: 1452 -ERER-----------------SYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCL 1493
E ER S E R + +PS +S E+S+DE+A+C A +C
Sbjct: 1557 KEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQ 1616
Query: 1494 QPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAP 1541
+P D+VDWVQCDG C++WFHQVCVGVSPEMAE EDYIC+ C K P
Sbjct: 1617 RPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGP 1664
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 1498 bits (3878), Expect = 0.0
Identities = 733/1276 (57%), Positives = 941/1276 (73%), Gaps = 24/1276 (1%)
Query: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
Query: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
Query: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
Query: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
Query: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
Query: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
Query: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
Query: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
Query: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
Query: 970 HWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQA 1029
W++KAK L+ARPRHS+ SL + V E + IPA+LPN +LK+++Q+AR+W VE +Q+
Sbjct: 954 RWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQS 1013
Query: 1030 GGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEV 1089
G L+ L L +GR IPV L +LP++E+ VA +AW+E TFL +NS ++LL+V
Sbjct: 1014 GSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQV 1073
Query: 1090 LCPRCDIGLLGL-KRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEA 1148
L PR DIG+ G K +++K+KE + K+K LE LSDLE L E+++TA +A E
Sbjct: 1074 LSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKER 1133
Query: 1149 RLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPS 1208
+E+EA+ SLR AN K+ + ++K C+C+K + M+QCELC+D FH SCV +P
Sbjct: 1134 EQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPK 1193
Query: 1209 ISQGLR---------IWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERT 1259
S + +LCP C RS +P LE IL LL SLQ++ VRLPEG+AL+ + ER
Sbjct: 1194 SSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERA 1253
Query: 1260 VNWQHRAQQLLSSGNL 1275
++WQ RA+Q L++ L
Sbjct: 1254 MSWQDRARQALATDEL 1269
Score = 70.9 bits (172), Expect = 9e-12
Identities = 57/186 (30%), Positives = 87/186 (46%), Gaps = 30/186 (16%)
Query: 1341 GVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKR 1400
G ++ EL+M LL+VSL E Q +++ L A P++ S E+ K
Sbjct: 1445 GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPL---KV 1501
Query: 1401 DGINSLERKLKRRLERE----GLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKL----- 1451
G +S E+K KR+LE+ G ++ + +KKM P+KKK+KL K KL
Sbjct: 1502 KGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLA 1561
Query: 1452 -ERER-----------------SYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCL 1493
E ER S E R + +PS +S E+S+DE+A+C A +C
Sbjct: 1562 KEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQ 1621
Query: 1494 QPEGDE 1499
+P D+
Sbjct: 1622 RPCKDK 1627
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 1356 bits (3510), Expect = 0.0
Identities = 741/1546 (47%), Positives = 980/1546 (63%), Gaps = 121/1546 (7%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
+FLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PRIQRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VER+ILDL+ L+K+V EEGG+
Sbjct: 67 PRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSL-RCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY ++ SG +L +C +P +
Sbjct: 127 AICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP-FDNEE 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTE------------- 250
KDKEYKPH IP RQSVQPS+ RRAKR++ + + + E+ E
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKM 245
Query: 251 ------ARTHNLRRR----MGCPTPKCENEKEMKSSIKQEPIERKDYIVENEK--EKPKS 298
A+ LR++ CP P ++E+ +K E K ++ E+ P+
Sbjct: 246 MGLGLMAKDKTLRKKDKEGPECP-PTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEP 304
Query: 299 RSKKA-------TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKG 349
+K +NA ++ YVC +C G+++D+LLLCDGCDD+YH FCL+PPL ++PKG
Sbjct: 305 CTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKG 364
Query: 350 DWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKE 409
WRCPKC+ EC +P EAFGFEQA R+YTL++FGEMAD+FK+DYFNMPVHMVPTELVEKE
Sbjct: 365 VWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKE 424
Query: 410 FWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQ 469
FWRLV++IEEDVTVEYGADI SKEFGSGFPV D K L+PEEEEY SGWNLN MPV+EQ
Sbjct: 425 FWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQ 484
Query: 470 SVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQ 529
SVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE
Sbjct: 485 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 544
Query: 530 LENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSG 589
LE VMKKL PELF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSG
Sbjct: 545 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 604
Query: 590 FNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVAS 649
FNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A+
Sbjct: 605 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAA 664
Query: 650 TVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCK 709
V K+M IM+++E+ LR+ + + G+ ++ER FELLPDDERQC+KCKTTCF+SA++C
Sbjct: 665 AVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDC 724
Query: 710 PGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAK 769
P LVCL H+ +LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE +
Sbjct: 725 PDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVE 784
Query: 770 INKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSG 829
+K+SL +AL E+ ++FP+++LL+ L+ +AE C S A L++G+ +R
Sbjct: 785 DGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVA 844
Query: 830 GGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAE 889
G Q+T+ ELR F+ Q+ LPC + Q +K +L +VE +Q +++ L+ S
Sbjct: 845 G----LQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 900
Query: 890 LQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVG 947
LQ LL+ + VE+P+ +++ ++EQARWL+EV++ L PS+ TL MR L+ G
Sbjct: 901 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRT-LAPSARRGTLAVMRGLLVAGAS 959
Query: 948 LAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNG 1007
+AP AV+KA A LQELLT++E W++KA L+AR +H +L ++E E IP +LPN
Sbjct: 960 VAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNI 1019
Query: 1008 AALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQ 1067
ALK+++ +AR W+ DV+ +Q G P LD L LV GR +PV L L +LE V
Sbjct: 1020 QALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAH 1079
Query: 1068 AWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSD 1127
+W+E A TFL +NS Y+LLEVLCP D G KR + KE K T+L LS
Sbjct: 1080 SWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKE--LGLYKSDTELLGLS- 1136
Query: 1128 LERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVD-----IKICLC- 1181
+ ++ S + E +E E + LR N K SPL IC+C
Sbjct: 1137 ----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAK-PSPLASSSTASSTTSICVCG 1191
Query: 1182 QKAPAAPMIQCELCRDAFHTSCVAVPSI---------SQGLRIW-------LCPHCRRSE 1225
Q A +QC+LC+D FH CV+VP + S L W LCP C RS
Sbjct: 1192 QVLAGAGALQCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSR 1251
Query: 1226 KPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSG 1285
+P LE IL LL +LQR+ VRLPEG+AL+ + ER ++WQ RA+Q L+S ++ + R+
Sbjct: 1252 RPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAE- 1310
Query: 1286 LLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPE 1345
L R QA N P S L + + G S V+PE
Sbjct: 1311 -LRQRLQAEPRPEEPPN---YPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPE 1366
Query: 1346 --------------------------------VNELLMEAQLLQVSLPEIQELYQTLLAK 1373
+ EL+ME LL+V+L E ++Q L A
Sbjct: 1367 EGSGKRDLELLSSLLPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAG 1426
Query: 1374 PSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTP 1433
P + R+ +E++ G R +LER+ +R+++R G E + ++ P
Sbjct: 1427 QPPDLERIRTLLELEKAERH----GSRARGRALERRRRRKVDRGG---EGDDPAREELEP 1479
Query: 1434 KKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQED 1479
K+++ S P + + E E E +P+ S S QE+
Sbjct: 1480 --KRVRSSGP-EAEEVQEEEELEEETGGEGPPAPIPTTGSPSTQEN 1522
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 1318 bits (3412), Expect = 0.0
Identities = 715/1550 (46%), Positives = 977/1550 (63%), Gaps = 115/1550 (7%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C P +
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253
KDKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
Query: 254 -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302
+ +++ CP +++ + ++ +E + K
Sbjct: 246 MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
Query: 303 ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ E
Sbjct: 306 HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 366 CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADIC 480
VTVEYGADI SKEFGSGFPV + K LSPEE+EY SGWNLN MPV++QSVL HI ADI
Sbjct: 426 VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADIS 485
Query: 481 GMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPE 540
GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE LE VMK L PE
Sbjct: 486 GMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPE 545
Query: 541 LFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAV 600
LF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSGFNQG+NFAEAV
Sbjct: 546 LFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAV 605
Query: 601 NFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIE 660
NFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A V K+M IM++
Sbjct: 606 NFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQ 665
Query: 661 DEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVK 720
+E+ LR+ + + GV ++ER FELLPDDERQC+KCKTTCF+SA++C P LVCL H+
Sbjct: 666 EERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHIN 725
Query: 721 ELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFK 780
+LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE + +K+S +
Sbjct: 726 DLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELR 785
Query: 781 ALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVN 840
AL E+ ++FP+++LL+ L+ + E C + L++G+ QLT+
Sbjct: 786 ALESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQ-------VARMDTPQLTLT 838
Query: 841 ELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEF 900
ELR + Q+ +LPC + Q +KD+L +VE +Q +++ L+ S L+ LL+ +
Sbjct: 839 ELRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQL 898
Query: 901 DVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVGLAPYSAVEKAM 958
VE+P+ +++ ++EQA+WL+EV+QA L PS+ +L M+ L+ +G +A +V+KA
Sbjct: 899 GVEVPEAHQLQQQVEQAQWLDEVKQA-LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKAR 957
Query: 959 ARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRAR 1018
A LQELLT++E W++KA L+AR +H +L ++E E IP +LPN ALK+++ +A+
Sbjct: 958 AELQELLTIAERWEEKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQ 1017
Query: 1019 DWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFL 1078
W+ DV+ +Q G P LD L LV GR +PV L L +LE V +W+E A TFL
Sbjct: 1018 AWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFL 1077
Query: 1079 TENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKET 1138
+NS Y+LLEVLCP D G KR + E + T+L LS + ++
Sbjct: 1078 KKNSCYTLLEVLCPCADAGSDSTKRS--RWMEKALGLYQCDTELLGLS-----AQDLRDP 1130
Query: 1139 ASAMATLGEARLREMEALQSLRLANEGK--LLSP--LQDVDIKICLCQKAPA-APMIQCE 1193
S + E +E E + LR N K L+P + IC+C + PA ++QC+
Sbjct: 1131 GSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCD 1190
Query: 1194 LCRDAFHTSCVAVPSI---------SQGLRIW-------LCPHCRRSEKPPLEKILPLLA 1237
LC+D FH CV+VP + S L W LCP C RS +P LE IL LL
Sbjct: 1191 LCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLV 1250
Query: 1238 SLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFV------------------- 1278
+LQR+ VRLPEG+AL+ + ER + WQ RA++ L+S ++ +
Sbjct: 1251 ALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEE 1310
Query: 1279 -----------QDRVGSGLLYSRWQASAGQVSDTNKVSQP----PGTTSFSLPDDWDNRT 1323
R GSG S+ Q G + + + V+ P PG S D + +
Sbjct: 1311 ASVYTSATACDPIREGSGNNISKVQ---GLLENGDSVTSPENMAPGKGS-----DLELLS 1362
Query: 1324 SYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRS 1383
S L P TG + + EL+ME LL+V+L E ++Q L A P R+
Sbjct: 1363 SLL--PQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1420
Query: 1384 SPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERW-ERVKKMRTPKKKKIKLSH 1442
E +G R +LER+ +R+ +G + E ++ + + + I
Sbjct: 1421 LLELEKFEH----QGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARSSGIMSQV 1476
Query: 1443 PKDMNNFKLERERSYELVRSAETHS--LPSDTSYSEQEDSEDEDAICPAV 1490
++ +++ + +R + + HS L + + + +DS A CP++
Sbjct: 1477 GREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDS-GSSAACPSL 1525
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 1303 bits (3371), Expect = 0.0
Identities = 715/1581 (45%), Positives = 977/1581 (61%), Gaps = 146/1581 (9%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203
+CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C P +
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
Query: 204 KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253
KDKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 186 KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
Query: 254 -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302
+ +++ CP +++ + ++ +E + K
Sbjct: 246 MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
Query: 303 ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ E
Sbjct: 306 HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
Query: 361 CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420
C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 366 CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
Query: 421 VTVEYGADIASKEFGSGFPVRDGKIKLSPEE----------------------------- 451
VTVEYGADI SKEFGSGFPV + K LSPEE
Sbjct: 426 VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPPKVL 485
Query: 452 --EEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSIN 509
+EY SGWNLN MPV++QSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSIN
Sbjct: 486 GLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSIN 545
Query: 510 YLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVY 569
YLHWGEPKTWYGVP AAE LE VMK L PELF SQPDLLHQLVT+MNPNTLM+H VPV
Sbjct: 546 YLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVV 605
Query: 570 RTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSH 629
RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH
Sbjct: 606 RTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSH 665
Query: 630 DEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDE 689
+E+ICKMA+ + LD+ +A V K+M IM+++E+ LR+ + + GV ++ER FELLPDDE
Sbjct: 666 EELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDE 725
Query: 690 RQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALK 749
RQC+KCKTTCF+SA++C P LVCL H+ +LC C + LRYRYTLD+L M++ LK
Sbjct: 726 RQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLK 785
Query: 750 LRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEK 809
+RAES++ WA V ALE + +K+S +AL E+ ++FP+++LL+ L+ + E
Sbjct: 786 IRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEA 845
Query: 810 CASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRV 869
C + L++G+ QLT+ ELR + Q+ +LPC + Q +KD+L +V
Sbjct: 846 CIAQVLGLVSGQ-------VARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQV 898
Query: 870 EDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLD 929
E +Q +++ L+ S L+ LL+ + VE+P+ +++ ++EQA+WL+EV+QA L
Sbjct: 899 EAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA-LA 957
Query: 930 PSSL--TLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSL 987
PS+ +L M+ L+ +G +A +V+KA A LQELLT++E W++KA L+AR +H
Sbjct: 958 PSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPP 1017
Query: 988 NSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGR 1047
+L ++E E IP +LPN ALK+++ +A+ W+ DV+ +Q G P LD L LV GR
Sbjct: 1018 ATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGR 1077
Query: 1048 SIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRK 1107
+PV L L +LE V +W+E A TFL +NS Y+LLEVLCP D G KR +
Sbjct: 1078 DLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRS--R 1135
Query: 1108 LKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGK- 1166
E + T+L LS + ++ S + E +E E + LR N K
Sbjct: 1136 WMEKALGLYQCDTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKP 1190
Query: 1167 -LLSP--LQDVDIKICLCQKAPA-APMIQCELCRDAFHTSCVAVPSI---------SQGL 1213
L+P + IC+C + PA ++QC+LC+D FH CV+VP + S L
Sbjct: 1191 SPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPL 1250
Query: 1214 RIW-------LCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRA 1266
W LCP C RS +P LE IL LL +LQR+ VRLPEG+AL+ + ER + WQ RA
Sbjct: 1251 LAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRA 1310
Query: 1267 QQLLSSGNLKFV------------------------------QDRVGSGLLYSRWQASAG 1296
++ L+S ++ + R GSG S+ Q G
Sbjct: 1311 RKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQ---G 1367
Query: 1297 QVSDTNKVSQP----PGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLME 1352
+ + + V+ P PG S D + +S L P TG + + EL+ME
Sbjct: 1368 LLENGDSVTSPENMAPGKGS-----DLELLSSLL--PQLTGPVLELPEAIRAPLEELMME 1420
Query: 1353 AQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKR 1412
LL+V+L E ++Q L A P R+ E +G R +LER+ +R
Sbjct: 1421 GDLLEVTLDENHSIWQLLQAGQPPDLDRIRTLLELEKFEH----QGSRTRSRALERRRRR 1476
Query: 1413 RLEREGLSSERW-ERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHS--LP 1469
+ +G + E ++ + + + I ++ +++ + +R + + HS L
Sbjct: 1477 QKVDQGRNVENLVQQELQSKRARSSGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLK 1536
Query: 1470 SDTSYSEQEDSEDEDAICPAV 1490
+ + + +DS A CP++
Sbjct: 1537 GNQNSLQHKDS-GSSAACPSL 1556
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 1221 bits (3160), Expect = 0.0
Identities = 687/1549 (44%), Positives = 934/1549 (60%), Gaps = 170/1549 (10%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84
EFLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP DWQPPFA +VD FT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 85 PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144
PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERK
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERK------------------ 108
Query: 145 VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTK 204
IL+ Y+L S +C P + K
Sbjct: 109 ---------------------------------ILDLYSL-----SKQCNTHP-FDNEVK 129
Query: 205 DKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART----------- 253
DKEYKPH IP RQSVQPS+ +RRAKR++ + + + E+ E +
Sbjct: 130 DKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKMM 189
Query: 254 ----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKA 303
+ +++ CP +++ + ++ +E + K
Sbjct: 190 GLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNH 249
Query: 304 TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQEC 361
++A +D Y+C +C G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+ EC
Sbjct: 250 SSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAEC 309
Query: 362 SKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDV 421
+P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV
Sbjct: 310 KQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDV 369
Query: 422 TVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICG 481
TVEYGADI SKEFGSGFPV + K LSPEE+EY SGWNLN MPV++QSVL HI ADI G
Sbjct: 370 TVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADISG 429
Query: 482 MKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPEL 541
MK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVP AAE LE VMK L PEL
Sbjct: 430 MKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPEL 489
Query: 542 FVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVN 601
F SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVN
Sbjct: 490 FDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVN 549
Query: 602 FCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIED 661
FCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+ + LD+ +A V K+M IM+++
Sbjct: 550 FCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQE 609
Query: 662 EKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKE 721
E+ LR+ + + GV ++ER FELLPDDERQC+KCKTTCF+SA++C P LVCL H+ +
Sbjct: 610 ERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHIND 669
Query: 722 LCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKA 781
LC C + LRYRYTLD+L M++ LK+RAES++ WA V ALE + +K+S +A
Sbjct: 670 LCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRA 729
Query: 782 LIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNE 841
L E+ ++FP+++LL+ L+ + E C + L++G+ QLT+ E
Sbjct: 730 LESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQ-------VARMDTPQLTLTE 782
Query: 842 LRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFD 901
LR + Q+ +LPC + Q +KD+L +VE +Q +++ L+ S L+ LL+ +
Sbjct: 783 LRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQLG 842
Query: 902 VELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDMRRLIDLGVGLAPYSAVEKAMA 959
VE+P+ +++ ++EQA+WL+EV+QA L PS+ +L M+ L+ +G +A +V+KA A
Sbjct: 843 VEVPEAHQLQQQVEQAQWLDEVKQA-LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARA 901
Query: 960 RLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARD 1019
LQELLT++E W++KA L+AR +H +L ++E E IP +LPN ALK+++ +A+
Sbjct: 902 ELQELLTIAERWEEKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQA 961
Query: 1020 WLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLT 1079
W+ DV+ +Q G P LD L LV GR +PV L L +LE V +W+E A TFL
Sbjct: 962 WIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLK 1021
Query: 1080 ENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETA 1139
+NS Y+LLEVLCP D G KR + E + T+L LS + ++
Sbjct: 1022 KNSCYTLLEVLCPCADAGSDSTKRS--RWMEKALGLYQCDTELLGLS-----AQDLRDPG 1074
Query: 1140 SAMATLGEARLREMEALQSLRLANEGK--LLSP--LQDVDIKICLCQKAPA-APMIQCEL 1194
S + E +E E + LR N K L+P + IC+C + PA ++QC+L
Sbjct: 1075 SVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDL 1134
Query: 1195 CRDAFHTSCVAVPSI---------SQGLRIW-------LCPHCRRSEKPPLEKILPLLAS 1238
C+D FH CV+VP + S L W LCP C RS +P LE IL LL +
Sbjct: 1135 CQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVA 1194
Query: 1239 LQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFV-------------------- 1278
LQR+ VRLPEG+AL+ + ER + WQ RA++ L+S ++ +
Sbjct: 1195 LQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEA 1254
Query: 1279 ----------QDRVGSGLLYSRWQASAGQVSDTNKVSQP----PGTTSFSLPDDWDNRTS 1324
R GSG S+ Q G + + + V+ P PG S D + +S
Sbjct: 1255 SVYTSATACDPIREGSGNNISKVQ---GLLENGDSVTSPENMAPGKGS-----DLELLSS 1306
Query: 1325 YLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSS 1384
L P TG + + EL+ME LL+V+L E ++Q L A P R+
Sbjct: 1307 LL--PQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRTL 1364
Query: 1385 PVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERW-ERVKKMRTPKKKKIKLSHP 1443
E +G R +LER+ +R+ +G + E ++ + + + I
Sbjct: 1365 LELEKFEH----QGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARSSGIMSQVG 1420
Query: 1444 KDMNNFKLERERSYELVRSAETHS--LPSDTSYSEQEDSEDEDAICPAV 1490
++ +++ + +R + + HS L + + + +DS A CP++
Sbjct: 1421 REEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDS-GSSAACPSL 1468
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 1154 bits (2984), Expect = 0.0
Identities = 629/1323 (47%), Positives = 833/1323 (62%), Gaps = 108/1323 (8%)
Query: 136 LVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSL-RCL 194
+V EEGG+ +CKDR+W ++A ++ + PGK +GS +R HYERI+ PY ++ SG +L +C
Sbjct: 51 IVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCN 110
Query: 195 QKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTE---- 250
+P + KDKEYKPH IP RQSVQPS+ RRAKR++ + + + E+ E
Sbjct: 111 TRP-FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKL 169
Query: 251 ---------------ARTHNLRRR----MGCPTPKCENEKEMKSSIKQEPIERKDYIVEN 291
A+ LR++ CP P ++E+ +K E K ++
Sbjct: 170 QIYGAGPKMMGLGLMAKDKTLRKKDKEGPECP-PTVVVKEELGGDVKVESTSPKTFLESK 228
Query: 292 EK--EKPKSRSKKA-------TNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLI 340
E+ P+ +K +NA ++ YVC +C G+++D+LLLCDGCDD+YH FCL+
Sbjct: 229 EELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLL 288
Query: 341 PPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHM 400
PPL ++PKG WRCPKC+ EC +P EAFGFEQA R+YTL++FGEMAD+FK+DYFNMPVHM
Sbjct: 289 PPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM 348
Query: 401 VPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWN 460
VPTELVEKEFWRLV++IEEDVTVEYGADI SKEFGSGFPV D K L+PEEEEY SGWN
Sbjct: 349 VPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWN 408
Query: 461 LNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWY 520
LN MPV+EQSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWY
Sbjct: 409 LNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWY 468
Query: 521 GVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVI 580
GVP AAE LE VMKKL PELF SQPDLLHQLVT+MNPNTLM+H VPV RTNQCAGEFVI
Sbjct: 469 GVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVI 528
Query: 581 TFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKA 640
TFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH+E+ICKMA+
Sbjct: 529 TFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACP 588
Query: 641 DVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCF 700
+ LD+ +A+ V K+M IM+++E+ LR+ + + G+ ++ER FELLPDDERQC+KCKTTCF
Sbjct: 589 EKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCF 648
Query: 701 MSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWAL 760
+SA++C P LVCL H+ +LC C + LRYRYTLD+L M++ LK+RAES++ WA
Sbjct: 649 LSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWAN 708
Query: 761 NVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNG 820
V ALE + +K+SL +AL E+ ++FP+++LL+ L+ +AE C S A L++G
Sbjct: 709 KVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSG 768
Query: 821 KRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLL 880
+ +R G Q+T+ ELR F+ Q+ LPC + Q +K +L +VE +Q +++ L
Sbjct: 769 QEAGPHRVAG----LQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREAL 824
Query: 881 SEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSL--TLDDM 938
+ S LQ LL+ + VE+P+ +++ ++EQARWL+EV++ L PS+ TL M
Sbjct: 825 ASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRT-LAPSARRGTLAVM 883
Query: 939 RRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIE 998
R L+ G +AP AV+KA A LQELLT++E W++KA L+AR +H +L ++E E
Sbjct: 884 RGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAE 943
Query: 999 EIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPR 1058
IP +LPN ALK+++ +AR W+ DV+ +Q G P LD L LV GR +PV L L +
Sbjct: 944 NIPVHLPNIQALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQ 1003
Query: 1059 LETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKK 1118
LE V +W+E A TFL +NS Y+LLEVLCP D G KR + KE K
Sbjct: 1004 LELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKE--LGLYKS 1061
Query: 1119 STKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVD--- 1175
T+L LS + ++ S + E +E E + LR N K SPL
Sbjct: 1062 DTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAK-PSPLASSSTAS 1115
Query: 1176 --IKICLC-QKAPAAPMIQCELCRDAFHTSCVAVPSI---------SQGLRIW------- 1216
IC+C Q A +QC+LC+D FH CV+VP + S L W
Sbjct: 1116 STTSICVCGQVLAGAGALQCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKF 1175
Query: 1217 LCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLK 1276
LCP C RS +P LE IL LL +LQR+ VRLPEG+AL+ + ER ++WQ RA+Q L+S ++
Sbjct: 1176 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVT 1235
Query: 1277 FVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSC 1336
+ R+ L R QA N P S L + + G S
Sbjct: 1236 ALLGRLAE--LRQRLQAEPRPEEPPN---YPAAPASDPLREGSGKDMPKVQGLLENGDSV 1290
Query: 1337 IPLHGVSPE-----------------------------VNELLMEAQLLQVSLPEIQELY 1367
V+PE + EL+ME LL+V+L E +
Sbjct: 1291 TSPEKVAPEEGSDLELLSSLLPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIP 1350
Query: 1368 QTL 1370
++L
Sbjct: 1351 ESL 1353
Score = 81.6 bits (200), Expect = 5e-15
Identities = 33/43 (76%), Positives = 38/43 (88%)
Query: 25 EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPP 67
+FLPPPECPVFEPSW EF DP +I KIRPIAE++GICK+RPP
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPP 49
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 137 bits (346), Expect = 6e-32
Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 26/238 (10%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T+R F ++A+ SD + P + EL E+++W+ + T + YGAD+ +
Sbjct: 93 TVREFRKIAN---SDKYCTPRYSEFEEL-ERKYWKNL-TFNPPI---YGADVNGTLY--- 141
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
E+++D WN+ + + V I G+ P+LY GM +SF
Sbjct: 142 --------------EKHVDE-WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFA 186
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY VP ++LE + K P S L +T+++
Sbjct: 187 WHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLIS 246
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCV 615
P L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF T W+ G+Q V
Sbjct: 247 PLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 28 PPPECPVFEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC-DVDKLHFTP 85
P F P+ EEF + +I I A + G+ KV PP +W+P + D+D L
Sbjct: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
Query: 86 RIQRL 90
IQ+L
Sbjct: 70 PIQQL 74
>gi|39653317 jumonji domain containing 2D [Homo sapiens]
Length = 523
Score = 137 bits (345), Expect = 8e-32
Identities = 83/243 (34%), Positives = 117/243 (48%), Gaps = 23/243 (9%)
Query: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
F Q + T GE S + P H +L E+++W+ + I YGADI
Sbjct: 86 FTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDL-ERKYWK--NRIYNSPI--YGADI 140
Query: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
+ F WNL ++ ++ + I G+ P+LY
Sbjct: 141 SGSLFDEN------------------TKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYF 182
Query: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
GM ++F WH ED YSINYLH GEPKTWY VP ++LE + ++L P L
Sbjct: 183 GMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFL 242
Query: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
V +++P L + +P R Q AGEF++TFP YH+GFN GFN AEA+NF T W+
Sbjct: 243 RHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWID 302
Query: 610 LGR 612
G+
Sbjct: 303 YGK 305
>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
sapiens]
Length = 1246
Score = 134 bits (337), Expect = 7e-31
Identities = 111/396 (28%), Positives = 183/396 (46%), Gaps = 39/396 (9%)
Query: 375 RDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEF 434
R +L TF A S F+ P E +E+E+WRLV + V V G + +
Sbjct: 818 RSVSLTTFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTH 873
Query: 435 GSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFS 494
GSGFPV GK E + GWNL +P S+L H+ A + G+ +PWL +GM FS
Sbjct: 874 GSGFPV--GK------SEPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFS 924
Query: 495 SFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVT 554
+ CW + + I+YLH G WY +P +LE+V+ L +L V
Sbjct: 925 TSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVM 984
Query: 555 IMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQC 614
I +P L + V+RT Q +G+FV+ FP ++ S G++ +E V+F T W +G +
Sbjct: 985 I-SPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFET 1043
Query: 615 VEHYRLLHRYCVFSHDEMICKMA-SKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLG 673
+ + H FS ++++ ++A ++A + ST+ + + + E R + + G
Sbjct: 1044 AKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAG 1103
Query: 674 VIDSER-----------------MDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVC- 715
+ S R + L ER+C C+ C++S + ++ C
Sbjct: 1104 LHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMV-VQENENVVFCL 1162
Query: 716 ---LHHVKELCSCPPYKYKLRYRYTLDDLYPMMNAL 748
L HV++ SC KL YRY + + ++N +
Sbjct: 1163 ECALRHVEKQKSC--RGLKLMYRYDEEQIISLVNQI 1196
Score = 79.0 bits (193), Expect = 3e-14
Identities = 45/127 (35%), Positives = 71/127 (55%), Gaps = 2/127 (1%)
Query: 31 ECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRL 90
E PV PS +EF DP +I +R E+ G+C+V PPPDW+P + D++ F +IQ +
Sbjct: 556 EIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLN-DEMRFVTQIQHI 614
Query: 91 NELEAQTRVKLNFLDQIAKYWELQGSTL-KIPHVERKILDLFQLNKLVAEEGGFAVVCKD 149
++L + + L I K+ + QG T+ ++P + LDL +L+ E GG V
Sbjct: 615 HKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDL 674
Query: 150 RKWTKIA 156
+KW K+A
Sbjct: 675 KKWNKLA 681
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 133 bits (335), Expect = 1e-30
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
Score = 31.2 bits (69), Expect = 8.1
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 1189 MIQCELCRDAFHTSCVAVPS--ISQGLRIWLCPHCRRS 1224
+I C C H SC +PS I G WLC C+R+
Sbjct: 715 LISCAKCCVRVHASCYGIPSHEICDG---WLCARCKRN 749
>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 1e-30
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 1e-30
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 133 bits (335), Expect = 1e-30
Identities = 64/154 (41%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP + LE + ++L P++ L V +++P L + +P Q AGEF
Sbjct: 209 WYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 133 bits (335), Expect = 1e-30
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 117 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 168
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 169 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 210
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 211 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 270
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 271 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 325
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 34 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 92
Query: 85 PRIQRL 90
IQ++
Sbjct: 93 APIQQM 98
Score = 31.2 bits (69), Expect = 8.1
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 1189 MIQCELCRDAFHTSCVAVPS--ISQGLRIWLCPHCRRS 1224
+I C C H SC +PS I G WLC C+R+
Sbjct: 737 LISCAKCCVRVHASCYGIPSHEICDG---WLCARCKRN 771
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 133 bits (335), Expect = 1e-30
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
Score = 31.2 bits (69), Expect = 8.1
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 1189 MIQCELCRDAFHTSCVAVPS--ISQGLRIWLCPHCRRS 1224
+I C C H SC +PS I G WLC C+R+
Sbjct: 715 LISCAKCCVRVHASCYGIPSHEICDG---WLCARCKRN 749
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 133 bits (335), Expect = 1e-30
Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)
Query: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
T++ F ++A++ K + P ++ +L E+++W+ ++ V YGADI + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
Query: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
WN+ + + V I G+ P+LY GM ++F
Sbjct: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
WH ED YSINYLH+GEPK+WY +P ++LE + + P L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
P+ L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF TV W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84
P C + F PS EEF + ++ + A + G+ KV PP +W+P C D+D L
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
Query: 85 PRIQRL 90
IQ++
Sbjct: 71 APIQQM 76
Score = 31.2 bits (69), Expect = 8.1
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 1189 MIQCELCRDAFHTSCVAVPS--ISQGLRIWLCPHCRRS 1224
+I C C H SC +PS I G WLC C+R+
Sbjct: 715 LISCAKCCVRVHASCYGIPSHEICDG---WLCARCKRN 749
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 2e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 2e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 132 bits (333), Expect = 2e-30
Identities = 65/154 (42%), Positives = 90/154 (58%)
Query: 459 WNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 518
WNL ++ + + I G+ P+LY GM ++F WH ED YSINYLH+GEPKT
Sbjct: 149 WNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKT 208
Query: 519 WYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEF 578
WY VP ++LE + ++L P L V +++P L + +P R Q AGEF
Sbjct: 209 WYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEF 268
Query: 579 VITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
++TFP YH+GFN GFN AEA+NF T W+ G+
Sbjct: 269 MVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 132 bits (331), Expect = 3e-30
Identities = 77/232 (33%), Positives = 116/232 (50%), Gaps = 23/232 (9%)
Query: 381 TFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPV 440
T GE S+ + P H +L E+++W+ ++ V+ YGADI+ +
Sbjct: 94 TVGEYRRLANSEKYCTPRHQDFDDL-ERKYWKNLTF----VSPIYGADISGSLYDDDV-- 146
Query: 441 RDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHI 500
+ WN+ ++ + V I G+ P+LY GM ++F WH
Sbjct: 147 ----------------AQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHT 190
Query: 501 EDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNT 560
ED YSINYLH+GEPK+WY +P ++LE + P L +T+++P
Sbjct: 191 EDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPII 250
Query: 561 LMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612
L + +P R Q AGEF+ITFP YH+GFN GFN AE+ NF T+ W+ G+
Sbjct: 251 LKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGK 302
Score = 32.7 bits (73), Expect = 2.8
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
Query: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQP 72
P C + F P+ EEF D ++ I A + G+ K+ PP +W+P
Sbjct: 11 PSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKP 56
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 76.3 bits (186), Expect = 2e-13
Identities = 34/71 (47%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 302 KATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLA-QE 360
K V+ VC +CG +D RLLLCD CD SYHT+CL PPL VPKG W+C C++ +
Sbjct: 1420 KGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQ 1479
Query: 361 CSKPQEAFGFE 371
C F E
Sbjct: 1480 CGAASPGFHCE 1490
Score = 58.5 bits (140), Expect = 5e-08
Identities = 20/59 (33%), Positives = 33/59 (55%)
Query: 298 SRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC 356
+R + + VC C ++ ++L+C+ CD YHTFCL PP+ ++P W+C C
Sbjct: 262 ARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKAC 320
Score = 40.4 bits (93), Expect = 0.013
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC-LAQECSKP 364
C +C + L C C YH CL L + W+CP+C + Q C KP
Sbjct: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKP 282
Score = 34.7 bits (78), Expect = 0.73
Identities = 15/50 (30%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 1175 DIKICLCQKAPA--APMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCR 1222
+ K+C + P + M+ CE C +HT C+ P W C CR
Sbjct: 272 ECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACR 321
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 72.8 bits (177), Expect = 2e-12
Identities = 30/56 (53%), Positives = 35/56 (62%)
Query: 302 KATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCL 357
K ++ VC CG D RLLLCD CD SYHT+CL PPL VPKG W+C C+
Sbjct: 1000 KGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
Score = 57.4 bits (137), Expect = 1e-07
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 311 VCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKC-LAQEC 361
VC C ++ ++L+CD CD YHTFCL P + VP W+C C + EC
Sbjct: 390 VCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIEC 441
Score = 40.0 bits (92), Expect = 0.017
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 294 EKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRC 353
++ RSK+ N C +C S D C C YH CL + + + W+C
Sbjct: 332 DQAPERSKEDAN------CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQC 385
Query: 354 PKC-LAQECSKPQE 366
P+C + Q C + E
Sbjct: 386 PECKVCQNCKQSGE 399
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 72.8 bits (177), Expect = 2e-12
Identities = 31/63 (49%), Positives = 38/63 (60%)
Query: 296 PKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
P +K + D C +CG + EDRLLLCDGCD YH CL PPL +VP +W CP+
Sbjct: 170 PVENTKASEEEEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPE 229
Query: 356 CLA 358
C A
Sbjct: 230 CAA 232
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 67.8 bits (164), Expect = 8e-11
Identities = 33/74 (44%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 283 ERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPP 342
E+ E E+EK S++A A D C CG N + +LLCD CD YHT CL PP
Sbjct: 868 EKSSAASEEEEEK---ESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPP 924
Query: 343 LHDVPKGDWRCPKC 356
L +P G+W CP C
Sbjct: 925 LMIIPDGEWFCPPC 938
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 66.6 bits (161), Expect = 2e-10
Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 32/157 (20%)
Query: 261 GCPTPKCENEK-EMKSSIKQEPIERKDYIVENEK-----EKPKSRSKKATNAVDLYV--- 311
G PK + K + + S K E ++ + +VE K EK K+ ++A ++V
Sbjct: 1111 GFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLG 1170
Query: 312 ----------------CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPK 355
C +C ++D+L+LCD C+ ++H FCL P L++VP G+W+CP
Sbjct: 1171 MLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPA 1230
Query: 356 CLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSD 392
C Q + + + G R+YT + E ++ +SD
Sbjct: 1231 C--QPATARRNSRG-----RNYTEESASEDSEDDESD 1260
Score = 36.2 bits (82), Expect = 0.25
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 28/138 (20%)
Query: 1097 GLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEAL 1156
G + K+K+RKL+ + S K E + D E+ + E + ASA+ A +RE +
Sbjct: 1111 GFMAPKQKRRKLQS------EDSAKTEEV-DEEKKMVEEAKVASALEKWKTA-IREAQTF 1162
Query: 1157 QSLRLANEGKLLSPL----------QDVDIKICLCQKAPAAPMIQCELCRDAFHTSCV-- 1204
+ + LL L ++ K+C +K +I C+ C AFH C+
Sbjct: 1163 SRMHV-----LLGMLDACIKWDMSAENARCKVCR-KKGEDDKLILCDECNKAFHLFCLRP 1216
Query: 1205 AVPSISQGLRIWLCPHCR 1222
A+ + G W CP C+
Sbjct: 1217 ALYEVPDG--EWQCPACQ 1232
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 65.9 bits (159), Expect = 3e-10
Identities = 28/62 (45%), Positives = 39/62 (62%)
Query: 299 RSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLA 358
RS +V+ CL+C G++++ LLLCDGCD H +C P + VP+GDW C CLA
Sbjct: 1666 RSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLA 1725
Query: 359 QE 360
Q+
Sbjct: 1726 QQ 1727
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 65.5 bits (158), Expect = 4e-10
Identities = 24/48 (50%), Positives = 33/48 (68%)
Query: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQ 359
C +C G++E+ LLLCDGCD HT+C P + +P GDW CP C+A+
Sbjct: 1934 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAK 1981
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,921,796
Number of Sequences: 37866
Number of extensions: 3224880
Number of successful extensions: 12831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 11851
Number of HSP's gapped (non-prelim): 1152
length of query: 1544
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1429
effective length of database: 13,892,928
effective search space: 19852994112
effective search space used: 19852994112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.