Guide to the Human Genome
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Search of human proteins with 57242793

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo
sapiens]
         (1241 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]  2477   0.0  
gi|6631090 interphotoreceptor matrix proteoglycan 1 [Homo sapiens]    213   1e-54
gi|91982772 mucin 17 [Homo sapiens]                                    65   3e-10
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ...    65   5e-10
gi|153070264 meprin A beta [Homo sapiens]                              53   2e-06
gi|239745235 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-05
gi|239756347 PREDICTED: similar to taste receptor protein 1 [Hom...    48   5e-05
gi|239750872 PREDICTED: similar to taste receptor protein 1 [Hom...    48   5e-05
gi|83367077 mucin 16 [Homo sapiens]                                    47   9e-05
gi|24041035 notch 2 preproprotein [Homo sapiens]                       46   3e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        45   3e-04
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    45   3e-04
gi|55770876 notch4 preproprotein [Homo sapiens]                        45   3e-04
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    45   4e-04
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            45   4e-04
gi|169170721 PREDICTED: similar to intestinal mucin [Homo sapiens]     45   4e-04
gi|24430141 fibrillin 1 precursor [Homo sapiens]                       45   6e-04
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]     45   6e-04
gi|148833508 notch1 preproprotein [Homo sapiens]                       44   0.001
gi|134244285 Notch homolog 3 [Homo sapiens]                            43   0.002
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             43   0.002
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             43   0.002
gi|194328809 latent transforming growth factor beta binding prot...    42   0.003
gi|18497288 latent transforming growth factor beta binding prote...    42   0.003
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        42   0.003
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                42   0.004
gi|153070262 meprin A alpha [Homo sapiens]                             41   0.008
gi|21264602 laminin alpha 5 [Homo sapiens]                             41   0.008
gi|7019499 peroxisome proliferator-activated receptor gamma, coa...    40   0.011
gi|122937283 6720455I24Rik homolog [Homo sapiens]                      40   0.014

>gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]
          Length = 1241

 Score = 2477 bits (6419), Expect = 0.0
 Identities = 1241/1241 (100%), Positives = 1241/1241 (100%)

Query: 1    MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT 60
            MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT
Sbjct: 1    MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT 60

Query: 61   KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA 120
            KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA
Sbjct: 61   KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA 120

Query: 121  FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE 180
            FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE
Sbjct: 121  FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE 180

Query: 181  LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE 240
            LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE
Sbjct: 181  LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE 240

Query: 241  QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE 300
            QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE
Sbjct: 241  QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE 300

Query: 301  NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE 360
            NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE
Sbjct: 301  NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE 360

Query: 361  TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA 420
            TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA
Sbjct: 361  TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA 420

Query: 421  WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE 480
            WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE
Sbjct: 421  WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE 480

Query: 481  VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV 540
            VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV
Sbjct: 481  VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV 540

Query: 541  PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG 600
            PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG
Sbjct: 541  PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG 600

Query: 601  LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ 660
            LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ
Sbjct: 601  LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ 660

Query: 661  ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA 720
            ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA
Sbjct: 661  ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA 720

Query: 721  PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES 780
            PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES
Sbjct: 721  PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES 780

Query: 781  ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL 840
            ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL
Sbjct: 781  ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL 840

Query: 841  ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV 900
            ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV
Sbjct: 841  ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV 900

Query: 901  VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV 960
            VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV
Sbjct: 901  VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV 960

Query: 961  VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN 1020
            VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN
Sbjct: 961  VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN 1020

Query: 1021 EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR 1080
            EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR
Sbjct: 1021 EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR 1080

Query: 1081 VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF 1140
            VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF
Sbjct: 1081 VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF 1140

Query: 1141 SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR 1200
            SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR
Sbjct: 1141 SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR 1200

Query: 1201 QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV 1241
            QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV
Sbjct: 1201 QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV 1241


>gi|6631090 interphotoreceptor matrix proteoglycan 1 [Homo sapiens]
          Length = 797

 Score =  213 bits (541), Expect = 1e-54
 Identities = 119/250 (47%), Positives = 163/250 (65%), Gaps = 17/250 (6%)

Query: 834  GVQDISLELDRIG-TDYYQPEQVQEQNGKVG---SYVEMSTSVHSTEMVSVAWPTEGGDD 889
            G +D+   LD +  +D   P +V E +  V     ++E +T V + + ++ +        
Sbjct: 511  GGEDMVRHLDEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTS-------S 563

Query: 890  LSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNL 949
            ++       LVVFFSLRV NM FS DLFNK+SLEY+ALEQ+F +LLVPYL+SNLTGF+ L
Sbjct: 564  MTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQL 623

Query: 950  EILNFRNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD 1009
            EILNFRNGS++VNS+MKFA SVP N+  AV+ +LEDF + A   ++L ID YSL++E  D
Sbjct: 624  EILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPAD 683

Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGK-CD 1068
            +A+PCKF AC EF++C+ N  + EA+CRC PGY S       SL  L+P  C    K C+
Sbjct: 684  QADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQ-----GSLDGLEPGLCGPGTKECE 738

Query: 1069 IMPGHGAICR 1078
            ++ G GA CR
Sbjct: 739  VLQGKGAPCR 748



 Score =  163 bits (413), Expect = 8e-40
 Identities = 132/515 (25%), Positives = 233/515 (45%), Gaps = 47/515 (9%)

Query: 78  RRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYW 137
           R +RS  FP GVK+CP ES+ + + +   Y+++RVCQEAVWEA+R F DR+P   EY  W
Sbjct: 67  RTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDW 126

Query: 138 MNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSELSSPVPVGDTSTLGDTT 197
           +++C+     +F++G NFS S EH  L+ +++          E+S+   +G+       +
Sbjct: 127 VSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPDRKDEISAEKTLGEPGETIVIS 186

Query: 198 LSVPHPEVDAYEGASESSLERPEESISNEI-ENVIEEATKPAGEQIAEF----------S 246
             V +  +  +          P++++ NEI +N + +   P  E+  EF          S
Sbjct: 187 TDVANVSLGPFP-------LTPDDTLLNEILDNTLNDTKMPTTERETEFAVLEEQRVELS 239

Query: 247 IHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKENDSGVD 306
           + L+ ++++ EL DS S ++Q L  +   +++  F  LPG+K+I VL FR  KE D    
Sbjct: 240 VSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSS 299

Query: 307 VYYAVT-----FNGEAISNTTWDLISLHSNKVEN----HGLVELDDKPTVVYTISNFRDY 357
               +T      + EA S  + DL+S  SNK+E+    HG +E D +P +  T ++ +  
Sbjct: 300 TEMQLTAIFKRHSAEAKSPAS-DLLSFDSNKIESEEVYHGTMEEDKQPEIYLTATDLKRL 358

Query: 358 IAETLQQNFLLGNSSLNPDPDSLQLIN-VRGVLRHQTEDLVWNTQSSSLQATPSSILDNT 416
           I++ L++   L       D  ++Q  + + G L     D      +S    T  + L   
Sbjct: 359 ISKALEEEQSL-------DVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPE 411

Query: 417 FQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSP 476
                P  +    +     D S  PP+     L    P     S   L         ++ 
Sbjct: 412 LPPVEPQLETVDGAEHGLPDTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATD 471

Query: 477 EVLEVSSLTL-----HSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESE--DFLSID 529
           + + V  LT+      +++   L    P AS + +  S   ED + +++E +  D  +  
Sbjct: 472 QTMLVPGLTIPTSDYSAISQLALGISHPPASSDDSRSSAGGEDMVRHLDEMDLSDTPAPS 531

Query: 530 SLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSS 564
            +P  S    VP   +    +    +++  Y+T+S
Sbjct: 532 EVPELSEYVSVPDHFL----EDTTPVSALQYITTS 562



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 2/111 (1%)

Query: 189 DTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAG-EQIAEFSI 247
           D   L DT      PE+  Y    +  LE      + +          P G E +  FS+
Sbjct: 520 DEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTSSMTIAPKGRELVVFFSL 579

Query: 248 HLLGKQYREELQDSSSFHHQHLEEEFIS-EVENAFTGLPGYKEIRVLEFRS 297
            +    +  +L + SS  ++ LE++F    V    + L G+K++ +L FR+
Sbjct: 580 RVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQLEILNFRN 630


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 25/237 (10%)

Query: 904  SLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNS 963
            ++ VT++ F+E+L N +S E++  +Q F E +   + S +  +  + I   R GS+VV  
Sbjct: 4191 TVTVTSVKFTEELKNHSSQEFQEFKQTFTEQM-NIVYSGIPEYVGVNITKLRLGSVVVEH 4249

Query: 964  ----RMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQAC 1019
                R K+       ++NA  ++ E    T   T  + I+    D+        C     
Sbjct: 4250 DVLLRTKYTPEYKTVLDNATEVVKEKI--TKVTTQQIMINDICSDMM-------CFNTTG 4300

Query: 1020 NEFSECLVNPWSGEAKCRC----FPGYLSVEERPCQSLC--DLQPDFCL----NDGKCDI 1069
             +     V  +  E  CR     +  Y  VE R  +  C    +P F +    N GKC  
Sbjct: 4301 TQVQNITVTQYDPEEDCRKMAKEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQ- 4359

Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRT 1126
            M   G  C C   E  WY G+ C +   + ++ G+  A VV +L+I  A++    R+
Sbjct: 4360 MSLSGPQCLCVTTETHWYSGETCNQGTQKSLVYGLVGAGVVLMLIILVALLMLVFRS 4416



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 92/439 (20%), Positives = 160/439 (36%), Gaps = 57/439 (12%)

Query: 407  ATP-SSILDNTFQAAWPSADESITSSIPPLDF----------SSGPPSATGRELWSESPL 455
            +TP +SIL +T   A     E+ T S  P+D           SS P +A G  +   +P 
Sbjct: 2927 STPLTSILVSTVPVA---GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTP- 2982

Query: 456  GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515
            G+  +       S M ++SS    E S+L   S TPA   T +  ++E  +S +     G
Sbjct: 2983 GERRTPLTSMSVSTMPVASS----EASTL---SRTPADTSTPVTTSTEASSSPTTAEGTG 3035

Query: 516  LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLT----SSIPFGLDS 571
            +     SE    + S+P S+    +P+ +  S    D   ++SP +T    SS P   + 
Sbjct: 3036 IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD---SNSPVVTSTEVSSSPTPAEG 3092

Query: 572  LTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSET---SSEKSAEPL 628
             +  +    + S  L    +    +    + + S   VD  T   + T   SS  ++E  
Sbjct: 3093 TSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGT 3152

Query: 629  SKPWLEDDDSLLP-AEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAV 687
            S P     +   P   +    +++V   DST   +          ST         G ++
Sbjct: 3153 SMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI 3212

Query: 688  PIFADTAAESASLTLPKHISEVP-GVDDYSVTKAPLILTSVAISASTDKSDQADAILRED 746
            P    T +E  +      +S  P    + S+     + ++  ++ ST+ S          
Sbjct: 3213 P--TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTS 3270

Query: 747  MEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD 806
            M   T S                  T  T +P S      T+++       L++TP    
Sbjct: 3271 MPTSTPSEG---------------STPLTSMPVS------TTTVASSETSTLSTTPADTS 3309

Query: 807  RLWLSVTQSTKLPPTTIST 825
                + +Q++  PP    T
Sbjct: 3310 TPVTTYSQASSSPPIADGT 3328



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 12/53 (22%), Positives = 29/53 (54%)

Query: 244  EFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFR 296
            E ++ +   ++ EEL++ SS   Q  ++ F  ++   ++G+P Y  + + + R
Sbjct: 4189 ELTVTVTSVKFTEELKNHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLR 4241


>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
            precursor [Homo sapiens]
          Length = 539

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 1/97 (1%)

Query: 1031 SGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGK 1090
            S E    C  G++      C+S+CDL P +C N G+C ++   GA CRC   +  W++G 
Sbjct: 352  SSENGTECRSGFVR-HNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGM 410

Query: 1091 HCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTL 1127
             CE  +++  ++ + + S   +L++   +  FF + L
Sbjct: 411  RCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKL 447


>gi|153070264 meprin A beta [Homo sapiens]
          Length = 701

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 2/76 (2%)

Query: 1045 VEERPCQSLCDL-QPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIG 1103
            ++  P  S+ DL     C NDG C +  G  A CRC+ GE+WWY G+ CE+  S    I 
Sbjct: 596  IQLTPAPSVQDLCSKTTCKNDGVCTVRDGK-AECRCQSGEDWWYMGERCEKRGSTRDTIV 654

Query: 1104 ITIASVVGLLVIFSAI 1119
            I ++S V +  +   I
Sbjct: 655  IAVSSTVAVFALMLII 670


>gi|239745235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 664

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 7/151 (4%)

Query: 888  DDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQ 947
            D +S T     +    +  +TN  FS  L N  S +++ L +     L P       GFQ
Sbjct: 210  DSVSSTPGPSHMTRSVTFTITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQ 269

Query: 948  NLEILNFRNGSIVVNSRMKFANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVE 1006
             + +L FR GS+ VN+ + F    P P+    ++ +     T+ +   NL++ + SL  +
Sbjct: 270  GIGVLVFRPGSVAVNASLVFGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSD 329

Query: 1007 SGD------EANPCKFQACNEFSECLVNPWS 1031
              D      E    +F A   F   L+ P S
Sbjct: 330  GADLITLARETISIRFTAMRSFLPQLLVPGS 360


>gi|239756347 PREDICTED: similar to taste receptor protein 1 [Homo
            sapiens]
          Length = 562

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 7/132 (5%)

Query: 907  VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMK 966
            +TN  FS  L N  S +++ L +     L P       GFQ + +L FR GS+ VN+ + 
Sbjct: 9    ITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQGIGVLVFRPGSVAVNASLV 68

Query: 967  FANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD------EANPCKFQAC 1019
            F    P P+    ++ +     T+ +   NL++ + SL  +  D      E    +F A 
Sbjct: 69   FGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSDGADLITLARETISIRFTAM 128

Query: 1020 NEFSECLVNPWS 1031
              F   L+ P S
Sbjct: 129  RSFLPQLLVPGS 140


>gi|239750872 PREDICTED: similar to taste receptor protein 1 [Homo
            sapiens]
          Length = 562

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 7/132 (5%)

Query: 907  VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMK 966
            +TN  FS  L N  S +++ L +     L P       GFQ + +L FR GS+ VN+ + 
Sbjct: 9    ITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQGIGVLVFRPGSVAVNASLV 68

Query: 967  FANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD------EANPCKFQAC 1019
            F    P P+    ++ +     T+ +   NL++ + SL  +  D      E    +F A 
Sbjct: 69   FGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSDGADLITLARETISIRFTAM 128

Query: 1020 NEFSECLVNPWS 1031
              F   L+ P S
Sbjct: 129  RSFLPQLLVPGS 140


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 144/644 (22%), Positives = 229/644 (35%), Gaps = 78/644 (12%)

Query: 398   WNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSG------PPSATGRELWS 451
             W T  +    T S  + N       +A   +TS  P +D  SG      PPS  G     
Sbjct: 11577 WLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTS--PGVDTRSGVPTTTIPPSIPGVVTSQ 11634

Query: 452   ESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHL 511
              +      ST   A P+       PE       T  S T    QTG  V    RT  S  
Sbjct: 11635 VTSSATDTST---AIPTLTPSPGEPET------TASSATHPGTQTGFTVPI--RTVPSSE 11683

Query: 512   VEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDS 571
              +   + V       +  S  +SSF+   P  T P M  S  +  SS  LT+  P   + 
Sbjct: 11684 PDTMASWVTHPPQTSTPVSRTTSSFSHSSPDAT-PVMATSPRTEASSAVLTTISPGAPEM 11742

Query: 572   LTSKVKDQ-LKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEP 627
             +TS++       S  +P  +    +     L S   +     T+P S      SE +A  
Sbjct: 11743 VTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASL 11802

Query: 628   LSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEP-LSGPA 686
               +P  E   +L P +       L+    S   +S              P   P +S   
Sbjct: 11803 TIRPGAETSTAL-PTQTTSSLFTLLVTGTSRVDLS--------------PTASPGVSAKT 11847

Query: 687   VPIFADTAAESASL----TLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAI 742
              P+      E++++    TL   + E  G+   S + A    +++ ++ S   S  + A 
Sbjct: 11848 APLSTHPGTETSTMIPTSTLSLGLLETTGLLATS-SSAETSTSTLTLTVSPAVSGLSSAS 11906

Query: 743   LREDMEQITESSNYEWFDSEVSMVKPDMQ-----TLWTILPESERVWTRTSSLEKLS-RD 796
             +  D  Q   S N E   S  S+  P+       T  T++P       +TS  E +S   
Sbjct: 11907 ITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTT 11966

Query: 797   ILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIM-----GVQDISLELDRIGTDYYQ 851
             IL +T   A  L  + +  T    TT    L   +       G+  ++ E     T Y  
Sbjct: 11967 ILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNH 12026

Query: 852   PEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLR--VTN 909
                +   +     Y   +TS   T   S    T      S T  +   +V F+L   +TN
Sbjct: 12027 RSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIP--SSTAATVPFMVPFTLNFTITN 12084

Query: 910   MMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSI-VVNSRMKFA 968
             + + ED+ +  S ++ A E+    LL P                FRN S+  + S  + A
Sbjct: 12085 LQYEEDMRHPGSRKFNATERELQGLLKPL---------------FRNSSLEYLYSGCRLA 12129

Query: 969   NSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEAN 1012
             +  P   ++A    ++  CT   +  +L +D+  L  E  +  N
Sbjct: 12130 SLRPEKDSSAT--AVDAICTHRPDPEDLGLDRERLYWELSNLTN 12171



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 106/532 (19%), Positives = 185/532 (34%), Gaps = 72/532 (13%)

Query: 413  LDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGL 472
            LD +  A+W      +T   P  + ++    +T    W   P  +  S+     P     
Sbjct: 5878 LDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVP----- 5932

Query: 473  SSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLP 532
               P +   SSL   +V+ +   + LPV S   TSG     D L    ++   L   SLP
Sbjct: 5933 --LPAITSHSSL-YSAVSGSSPTSALPVTS-LLTSGRRKTIDML----DTHSELVTSSLP 5984

Query: 533  SSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKV--------SP 584
            S+S       E + S   ++         T+    G  +   K+   + +         P
Sbjct: 5985 SAS---SFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPP 6041

Query: 585  FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEI 644
             +  + ME  ++     GS   + VD             S  PL+    ED  +L+    
Sbjct: 6042 KVTGSMMEDAIVSTSTPGSPETKNVD-----------RDSTSPLTPELKEDSTALVMNST 6090

Query: 645  EDKKLVLVD-KMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLP 703
             +   V     +D+  ++S+     +D        +   S    P  + + + S  LT+ 
Sbjct: 6091 TESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTIS 6150

Query: 704  KHISEVPGVDDYSVT---KAPLILTSVAISASTDKSDQAD-------AILREDMEQITES 753
             H +         VT   +  L  +++A SA T  +   D       +++  D+  + ++
Sbjct: 6151 THKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKT 6210

Query: 754  SNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVT 813
            S +     E + +      L T  P        TS+L++ S   L S           +T
Sbjct: 6211 SPFS--AEEANSLSSQAPLLVTTSPSPV-----TSTLQEHSTSSLVSVTSVPTPTLAKIT 6263

Query: 814  -QSTKLPPTTIS------TLLEDEVIMGVQ----DISLELDRIGT-----DYYQPEQVQE 857
               T L P T S      TL   E           I+  +  +GT     ++Y       
Sbjct: 6264 DMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDS 6323

Query: 858  QNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTN 909
               K  S V + TS     +VS + P         ++T+ +L+  F LR T+
Sbjct: 6324 DPYKATSAV-VITSTSGDSIVSTSMPRSSAMKKIESETTFSLI--FRLRETS 6372



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 52/211 (24%), Positives = 86/211 (40%), Gaps = 26/211 (12%)

Query: 404   SLQATPSSILDNTFQAAWPSADESITSSIPP-----LDFSSGPPSATGRELWSESPLGDL 458
             SL  T S  + +T   + PS+  S+TS + P      D S+ P ++    L S + +  L
Sbjct: 10026 SLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNL-SGTSVEIL 10084

Query: 459   VSTHKLAFPSKMGLSSSPEVLEV----------SSLTLHS-VTPAVLQTGLPVASEERTS 507
              ++       K+  SSS  V  V          SS+++HS  + A    G P +  E + 
Sbjct: 10085 AASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSI 10144

Query: 508   GSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPF 567
              + +  +      E+E F  +    +S F     ++T  S++ S V+ T++P    S   
Sbjct: 10145 STSMPANFETTGFEAEPFSHL----TSGF-----RKTNMSLDTSSVTPTNTPSSPGSTHL 10195

Query: 568   GLDSLTSKVKDQLKVSPFLPDASMEKELIFD 598
                S T         SP  P AS   E+  D
Sbjct: 10196 LQSSKTDFTSSAKTSSPDWPPASQYTEIPVD 10226



 Score = 31.2 bits (69), Expect = 6.4
 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 895   TSGALVVFFSLR--VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTG 945
             T+G L+V F+L   +TN+ + ED+    S ++   E+    LL P  ++   G
Sbjct: 12538 TAGPLLVLFTLNFTITNLKYEEDMHRPGSRKFNTTERVLQTLLGPMFKNTSVG 12590


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 33/129 (25%), Positives = 48/129 (37%), Gaps = 7/129 (5%)

Query: 984  EDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYL 1043
            E  C T +N             E     +PC+   C     C+     G+A CRC  G+ 
Sbjct: 38   EGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT 97

Query: 1044 SVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHC---EEFVSEPV 1100
              + +   S        CLN G C ++      C C+VG    + GK C   +  +S P 
Sbjct: 98   GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG----FTGKECQWTDACLSHPC 153

Query: 1101 IIGITIASV 1109
              G T  +V
Sbjct: 154  ANGSTCTTV 162



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 26/156 (16%)

Query: 955  RNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLA-----IDKYSLDVESGD 1009
            +NG   ++    F  S PP     +     D C    + +N       I  YS     G 
Sbjct: 1197 QNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256

Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFP---GYLSV-----EERPCQSLCDLQPDF- 1060
                C+     + +ECL NP S E    C      YL V       R C++  D+ P   
Sbjct: 1257 AGERCE----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMP 1312

Query: 1061 CLNDGKCDI---MPGHGAICRCRVGENWWYRGKHCE 1093
            CLN G C +   MP  G ICRC  G    + G  C+
Sbjct: 1313 CLNGGTCAVASNMP-DGFICRCPPG----FSGARCQ 1343



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 16/89 (17%)

Query: 1011 ANPCKFQA-CNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDI 1069
            +NPC+  A C++F         G  +C C PGY  V        C  QP  C N G C  
Sbjct: 1155 SNPCQHGATCSDFI--------GGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCID 1204

Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSE 1098
            +  H   C C  G     RG  CEE + +
Sbjct: 1205 LVNHFK-CSCPPGT----RGLLCEENIDD 1228



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 13/79 (16%)

Query: 1036 CRCFPGYLSVEERPCQSLCDLQPDFCLNDGKC-DIMPGHGAICRCRVGENWWYRGKHCE- 1093
            C C PGY+          C   P  CLNDG+C D++ G+   C C+ G +    G +CE 
Sbjct: 593  CICNPGYMGAICSDQIDECYSSP--CLNDGRCIDLVNGYQ--CNCQPGTS----GVNCEI 644

Query: 1094 ---EFVSEPVIIGITIASV 1109
               +  S P I GI +  +
Sbjct: 645  NFDDCASNPCIHGICMDGI 663



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 7/86 (8%)

Query: 1013 PCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPG 1072
            PC    C   + C  +P      C C PG+           C  +P  C+N G C    G
Sbjct: 836  PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQG 893

Query: 1073 HGAICRCRVGENWWYRGKHCEEFVSE 1098
               +C C  G    + G  CEE + +
Sbjct: 894  -SYMCECPPG----FSGMDCEEDIDD 914



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 6/86 (6%)

Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDL-QPDFCLNDGKCDIMPG 1072
            C    C++ + C  NP +G+  C C  GY   +       C +   + C + GKC    G
Sbjct: 379  CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438

Query: 1073 HGAICRCRVGENWWYRGKHCEEFVSE 1098
                C C  G    Y G  CE  ++E
Sbjct: 439  -AFHCECLKG----YAGPRCEMDINE 459



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 30/112 (26%), Positives = 41/112 (36%), Gaps = 19/112 (16%)

Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPG----YLSVEERPCQSLCD----LQPDFCLN 1063
            N C    C     C+      E++C C  G    Y  V    C         L    C +
Sbjct: 1065 NLCSRSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQH 1122

Query: 1064 DGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSE----PVIIGITIASVVG 1111
             G C I  G+   C+C +G    Y G +CEE + E    P   G T +  +G
Sbjct: 1123 SGVC-INAGNTHYCQCPLG----YTGSYCEEQLDECASNPCQHGATCSDFIG 1169


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 106/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%)

Query: 401  QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460
            +SS+  + P S    T   A+P   +S T+S    D S  P ++   +  +E+ L    +
Sbjct: 1467 ESSTSHSQPGS----THTTAFP---DSTTTS----DLSQEPTTSHSSQGSTEATLSPGST 1515

Query: 461  THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520
            T            SSP   E + L   ++T  +++   P  S   +  + L      +  
Sbjct: 1516 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575

Query: 521  ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577
              E+  +  S PSSS T P P  T  +  +   +  S P  T +  F   S T   S+  
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635

Query: 578  DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628
              +  SP        P  S    L+ +      S    +    P S T+   SEKS    
Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 1695

Query: 629  SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688
            S P    D +L PA      +       S +  + HS+      +T FP    + G +  
Sbjct: 1696 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 1745

Query: 689  IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748
                TA+ S+           PG  D +++      +S+   ++T  S            
Sbjct: 1746 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 1783

Query: 749  QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806
                        S  + + PD  T   +L  S  V + T S         ++T Q     
Sbjct: 1784 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1831

Query: 807  -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865
             + W S   +   PPTT S  +E           L     G+    P      +      
Sbjct: 1832 FQSWPSSKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 1880

Query: 866  VEMSTSVHSTEMVSVAWPT 884
             E ST+VHS+ + +   P+
Sbjct: 1881 SEESTTVHSSPVATATTPS 1899



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 105/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%)

Query: 401  QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460
            +SS+  + P S    T   A+P  D + TS +     S  P ++   +  +E+ L    +
Sbjct: 3024 ESSTSHSQPGS----THTTAFP--DSTTTSGL-----SQEPTASHSSQGSTEATLSPGST 3072

Query: 461  THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520
            T            SSP   E + L   ++T  +++   P  S   +  + L      +  
Sbjct: 3073 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 3132

Query: 521  ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577
              E+  +  S PSSS T P P  T  +  +   +  S P  T +  F   S T   S+  
Sbjct: 3133 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 3192

Query: 578  DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628
              +  SP        P  S    L+ +      S    +    P S T+   SEKS    
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252

Query: 629  SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688
            S P    D +L PA      +       S +  + HS+      +T FP    + G +  
Sbjct: 3253 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 3302

Query: 689  IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748
                TA+ S+           PG  D +++      +S+   ++T  S            
Sbjct: 3303 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSGPG--------- 3340

Query: 749  QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806
                        S  + + PD  T   +L  S  V + T S         ++T Q     
Sbjct: 3341 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 3388

Query: 807  -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865
             + W +   +T  PPTT S  +E           L     G+    P      +      
Sbjct: 3389 FQSWPNSKDTTPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 3437

Query: 866  VEMSTSVHSTEMVSVAWPT 884
             E ST+VHS+ + +   P+
Sbjct: 3438 SEESTTVHSSPVATATTPS 3456



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 105/499 (21%), Positives = 171/499 (34%), Gaps = 81/499 (16%)

Query: 401  QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460
            +SS+  + P S    T   A+P  D + TS +     S  P ++   +  +E+ L    +
Sbjct: 4107 ESSTSHSQPGS----THTTAFP--DSTTTSGL-----SQEPTTSHSSQGSTEATLSPGST 4155

Query: 461  THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520
            T            SSP   E + L   ++T  +++   P  S   +  + L      +  
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTG 4215

Query: 521  ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577
              E+  +  S PSSS T P P  T     +   +  S P  T +  F   S T   S+  
Sbjct: 4216 LQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 4275

Query: 578  DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628
              +  SP        P  S    L+ +      S    +    P S T+   SEKS    
Sbjct: 4276 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 4335

Query: 629  SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688
            S P    D +L PA      +       S +  + HS+      +T FP    + G +  
Sbjct: 4336 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSMHTTAFPSSTTMPGVSQ- 4385

Query: 689  IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748
                TA+ S+           PG  D +++      +S+   ++T  S            
Sbjct: 4386 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 4423

Query: 749  QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806
                        S  + + PD  T   +L  S  V + T S         ++T Q     
Sbjct: 4424 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 4471

Query: 807  -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865
             + W +   +T  PPTT S  +E           L     G+    P      +      
Sbjct: 4472 FQSWPNSKDTTPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 4520

Query: 866  VEMSTSVHSTEMVSVAWPT 884
             E ST+VHS+ + +   P+
Sbjct: 4521 SEESTTVHSSPVATATTPS 4539



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%)

Query: 369  GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
            G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 2559 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 2609

Query: 429  TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
            + S P   D +  P S T      ES        STH   FP     ++S  ++E S+  
Sbjct: 2610 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 2665

Query: 486  LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
            +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 2666 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTTF---QTHPASTHTTPSPPSTA 2711

Query: 546  PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
             +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 2712 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2756



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%)

Query: 369  GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
            G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 2085 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 2135

Query: 429  TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
            + S P   D +  P S T      ES        STH   FP     ++S  ++E S+  
Sbjct: 2136 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 2191

Query: 486  LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
            +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 2192 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 2237

Query: 546  PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
             +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 171/819 (20%), Positives = 293/819 (35%), Gaps = 120/819 (14%)

Query: 367  LLGNSSLNP-DPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPS-- 423
            LLG S+ +P    S++   + G     T     + +S++  ++PSS     F A+  +  
Sbjct: 4657 LLGESTTSPISSGSMETTALPG----STTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLG 4712

Query: 424  -ADESITSSIPPLDFSSGPPSA--TGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEV 478
             ++ES T    P+  ++ P  A  T   L  ES        ST  + FP     S   E 
Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE- 4771

Query: 479  LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQ 538
                S T HS T   +       S   ++ S LVE+   +   S   ++    P SS T 
Sbjct: 4772 ---ESRTSHSSTTHTI-------SSPPSTTSALVEEP-TSYHSSPGSIATTHFPESSTTS 4820

Query: 539  PVPKETIPSMEDSDVS--------LTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
               +E+  S    D +         T+S  +  S  F +      ++  L  +   P  S
Sbjct: 4821 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISP--GSMETTLASTATTPGLS 4878

Query: 591  MEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLV 650
             +  +++       S +  D    P S TSS  S EP S          L ++ E     
Sbjct: 4879 AKSTILYS------SSRSPDQTLSPASMTSSSISGEPTS----------LYSQAESTHTT 4922

Query: 651  LVDKMDSTDQISKHSKYEHDD----RSTHFPEEEPLSGPAVPIFADTAAESASL-TLPKH 705
                  +T  +S+ S   H       +T  P     S  A       +   ++L T+   
Sbjct: 4923 AFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPA 4982

Query: 706  ISEVPGVDDYSVT--KAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEV 763
             + VPG+ + S T   +P    + A S S   S     I  +      +S  +       
Sbjct: 4983 STTVPGLSEESTTFYSSPGSTETTAFSHSNTMS-----IHSQQSTPFPDSPGFTHTVLPA 5037

Query: 764  SMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTI 823
            ++   D+    T    S      T    + +   L   P +   +  S T +T  P ++ 
Sbjct: 5038 TLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTF-YISPSPTYTTLFPASSS 5096

Query: 824  STLLEDEVIMGVQDISLELDRIGTDYYQP------EQVQEQNGKVGSYVEMSTSVHSTEM 877
            ++ L +E        S     + T+  +       ++ Q  NGK     +          
Sbjct: 5097 TSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGYVGYQCLSP 5156

Query: 878  VSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVP 937
            +  ++P E  + L+ T       +  +++VT   F+E + + +S EY+     F   +  
Sbjct: 5157 LE-SFPVETPEKLNAT-------LGMTVKVTYRNFTEKMNDASSQEYQNFSTLFKNRMDV 5208

Query: 938  YLQS-NLTGFQNLEILNFRNGSIVVNSRM---------------KFANSVPPNVNNAVYM 981
             L+  NL  ++ + I    NGSIVV + +                 A  V   + N    
Sbjct: 5209 VLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYTLEYEELFENLAEIVKAKIMNETRT 5268

Query: 982  IL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEANPCKFQACNEFSECL-VNPWSGEA 1034
             L   D C  A   Y+  +  +D     V  G D    C  +A   +++   V+   G+ 
Sbjct: 5269 TLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQEQCTQKAAEGYTQFYYVDVLDGKL 5325

Query: 1035 KC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHC 1092
             C  +C  G  S      Q  C+L        G C +    G  C C      WY G+ C
Sbjct: 5326 ACVNKCTKGTKS------QMNCNL--------GTCQLQRS-GPRCLCPNTNTHWYWGETC 5370

Query: 1093 EEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHH 1131
            E  +++ ++ GI  A +  LL+    +I  F  + +  H
Sbjct: 5371 EFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQRKRH 5409



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 59/225 (26%), Positives = 91/225 (40%), Gaps = 30/225 (13%)

Query: 369  GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
            G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 1002 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 1052

Query: 429  T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
            + SS    D +  P S T      ES     +  STH   FP     ++S  ++E S+  
Sbjct: 1053 SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS---TTSSGIVEAST-R 1108

Query: 486  LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
            +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 1109 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 1154

Query: 546  PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
             +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 1199



 Score = 38.1 bits (87), Expect = 0.053
 Identities = 58/225 (25%), Positives = 89/225 (39%), Gaps = 30/225 (13%)

Query: 369  GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
            G++     PDS       G+ RH T      T  SS  +T +++L  +   +  S + + 
Sbjct: 3642 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGSSQESTT 3692

Query: 429  T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
            + SS    D +  P S T      ES        STH   FP     ++S  ++E S+  
Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 3748

Query: 486  LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
            +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 3749 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 3794

Query: 546  PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
             +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 3795 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 60/284 (21%), Positives = 92/284 (32%), Gaps = 31/284 (10%)

Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526
           P      SSP   + + L  ++ T  +L+   PV S   T   H      ++     +  
Sbjct: 362 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSS--TGSPHTTLSPSSSTTHEGEPT 419

Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583
           +  S PSS  T P P  T  +      +  SSP  T +  F   S T   S+    +  S
Sbjct: 420 TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS 479

Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637
           P        P  S     + +      S      + +P S T+S  S E           
Sbjct: 480 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE----------- 528

Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEH---DDRSTHFPEEEPLSGPAVPIFADTA 694
               A              ST     H+ Y        +THF +   +SG +    A  +
Sbjct: 529 ---SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 585

Query: 695 AESASLTLPKHISEVPGVDDYSVTKAPL---ILTSVAISASTDK 735
           +  A  T        P V     T +P+    + + A+  ST K
Sbjct: 586 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK 629



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 98/434 (22%), Positives = 157/434 (36%), Gaps = 41/434 (9%)

Query: 416  TFQAAWPSADESI------TSSIPPLDFSS-GPPSATGRELWSESPLGDLVSTHKLAFPS 468
            TFQ+ WPS+ +++      TS+   L  +S G PS+T    +S S      ST       
Sbjct: 1831 TFQS-WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS------STTLGRSEE 1883

Query: 469  KMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPV-ASEERTSGSHLVEDGLANVEESEDFLS 527
               + SSP     +     S T  +++      +S   T   H  E   A+    E   S
Sbjct: 1884 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE---S 1940

Query: 528  IDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLP 587
              S  S++ T   P  T  ++ +   S  SSP  T++  F   S TS   ++   S    
Sbjct: 1941 RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 2000

Query: 588  DASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEP--LSKPWLEDDDSLLPAEIE 645
            DA+    L          G+     T P S  S E +A P   + P L +  +   +   
Sbjct: 2001 DATGTIVLPARSTTSVLLGEST---TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 2057

Query: 646  DKKLVLVDKMDSTDQISKHSKYEH----DDRSTHFPEEEPLSG-PAVPIFADTAAESASL 700
                 L     ++  +S+ S   H       +T FP+     G       + ++  S   
Sbjct: 2058 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 2117

Query: 701  TLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFD 760
            TL    +   G    S T       S   S  T  S  +   L    E  T  S+     
Sbjct: 2118 TLLPASTTTSGPSQESTTS-----HSSPGSTDTALSPGSTTALSFGQESTTFHSSP---G 2169

Query: 761  SEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTP-----QSADRLWLSVTQS 815
            S  + + PD  T   I+  S RV + T S         +++P      +A +   + T +
Sbjct: 2170 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHT 2229

Query: 816  TKLPPTTISTLLED 829
            T  PP+T +  +E+
Sbjct: 2230 TPSPPSTATAPVEE 2243



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 52/245 (21%), Positives = 85/245 (34%), Gaps = 20/245 (8%)

Query: 467  PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526
            P      SSP   E + L  ++    +L+   PV S   T   H       +     +  
Sbjct: 4413 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGEST 4470

Query: 527  SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583
            +  S P+S  T P P  T  +  +   +   SP  T +  F   S T   S+    +  S
Sbjct: 4471 TFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS 4530

Query: 584  PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637
            P        P  S    L+ +      S      + +P S T+S +  E  +        
Sbjct: 4531 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSH-SSTTH 4589

Query: 638  SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAES 697
            ++  A      LV        +  S HS       +THFP+    SG +    A  +++ 
Sbjct: 4590 TISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQD 4641

Query: 698  ASLTL 702
            A+ T+
Sbjct: 4642 ATGTI 4646



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 51/245 (20%), Positives = 85/245 (34%), Gaps = 20/245 (8%)

Query: 467  PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526
            P      S P   E + L  ++    +L+   PV S   T   H       +     +  
Sbjct: 3330 PESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGEST 3387

Query: 527  SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583
            +  S P+S  T P P  T  +  +   +   SP  T +  F   S T   S+    +  S
Sbjct: 3388 TFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS 3447

Query: 584  PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637
            P        P  S    L+ +      S      + +P S+T+S +  E  +        
Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH-SSTTH 3506

Query: 638  SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAES 697
            ++  A      LV        +  S HS       +THFP+    SG +    A  +++ 
Sbjct: 3507 TISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQD 3558

Query: 698  ASLTL 702
            A+ T+
Sbjct: 3559 ATGTI 3563



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 48/255 (18%), Positives = 99/255 (38%), Gaps = 22/255 (8%)

Query: 403  SSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTH 462
            SS  +T S++++    +   S   + T+  P    +SG    +     S+   G +V   
Sbjct: 4592 SSAPSTTSALVEEP-TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 4650

Query: 463  KLAFPSKMGLSSSPEV----LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLAN 518
            +      +G S++  +    +E ++L   + TP + +      S   ++ +         
Sbjct: 4651 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTT 4710

Query: 519  VEESEDFLSIDSLPSSSFTQPVP-KETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVK 577
            +  SE+  ++ S P ++ T P P + T   + +   +  SSP  T ++ F   S  S   
Sbjct: 4711 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 4770

Query: 578  DQLKVS-----------PFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAE 626
            ++ + S           P    A +E+   +    GS     +    +P S T+S +S E
Sbjct: 4771 EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS-----IATTHFPESSTTSGRSEE 4825

Query: 627  PLSKPWLEDDDSLLP 641
              +     D + + P
Sbjct: 4826 STASHSSPDTNGITP 4840



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 67/307 (21%), Positives = 112/307 (36%), Gaps = 51/307 (16%)

Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455
           +S++  + P S     F  +   P   +  T   SS  P D +  P S T       S L
Sbjct: 663 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 716

Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515
           G          P      S P   E + L  ++    +L+  +PV S  R+  + L   G
Sbjct: 717 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 766

Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575
             +     +  +  S PSS  T+P P  T  +  +   +   SP   SSIP      T+ 
Sbjct: 767 --STTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 815

Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635
           +  +   S       +E+   +    GS        + +P S+T+S +  E  +      
Sbjct: 816 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 864

Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695
             ++  A      LV        +  S HS       +THFP+    SG +    A  ++
Sbjct: 865 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSS 916

Query: 696 ESASLTL 702
           + A+ T+
Sbjct: 917 QDATGTI 923


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 106/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%)

Query: 401  QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460
            +SS+  + P S    T   A+P   +S T+S    D S  P ++   +  +E+ L    +
Sbjct: 954  ESSTSHSQPGS----THTTAFP---DSTTTS----DLSQEPTTSHSSQGSTEATLSPGST 1002

Query: 461  THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520
            T            SSP   E + L   ++T  +++   P  S   +  + L      +  
Sbjct: 1003 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062

Query: 521  ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577
              E+  +  S PSSS T P P  T  +  +   +  S P  T +  F   S T   S+  
Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122

Query: 578  DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628
              +  SP        P  S    L+ +      S    +    P S T+   SEKS    
Sbjct: 1123 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 1182

Query: 629  SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688
            S P    D +L PA      +       S +  + HS+      +T FP    + G +  
Sbjct: 1183 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 1232

Query: 689  IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748
                TA+ S+           PG  D +++      +S+   ++T  S            
Sbjct: 1233 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 1270

Query: 749  QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806
                        S  + + PD  T   +L  S  V + T S         ++T Q     
Sbjct: 1271 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318

Query: 807  -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865
             + W S   +   PPTT S  +E           L     G+    P      +      
Sbjct: 1319 FQSWPSSKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 1367

Query: 866  VEMSTSVHSTEMVSVAWPT 884
             E ST+VHS+ + +   P+
Sbjct: 1368 SEESTTVHSSPVATATTPS 1386



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 59/225 (26%), Positives = 91/225 (40%), Gaps = 30/225 (13%)

Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
           G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 489 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 539

Query: 429 T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
           + SS    D +  P S T      ES     +  STH   FP     ++S  ++E S+  
Sbjct: 540 SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS---TTSSGIVEAST-R 595

Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
           +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 596 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 641

Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
            +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 642 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 686



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 69/292 (23%), Positives = 112/292 (38%), Gaps = 45/292 (15%)

Query: 867  EMSTSVH-STEMVSVAWPTEGGDDLS-YTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEY 924
            E ST+ H S    S    TE  + L+  T       +  +++VT   F+E + + +S EY
Sbjct: 1573 EESTTFHTSPSFTSTIVSTESLETLAPETPEKLNATLGMTVKVTYRNFTEKMNDASSQEY 1632

Query: 925  KALEQRFLELLVPYLQS-NLTGFQNLEILNFRNGSIVVNSRM---------------KFA 968
            +     F   +   L+  NL  ++ + I    NGSIVV + +                 A
Sbjct: 1633 QNFSTLFKNRMDVVLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYTLEYEELFENLA 1692

Query: 969  NSVPPNVNNAVYMIL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEANPCKFQACNEF 1022
              V   + N     L   D C  A   Y+  +  +D     V  G D    C  +A   +
Sbjct: 1693 EIVKAKIMNETRTTLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQEQCTQKAAEGY 1749

Query: 1023 SECL-VNPWSGEAKC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRC 1079
            ++   V+   G+  C  +C  G  S      Q  C+L        G C +    G  C C
Sbjct: 1750 TQFYYVDVLDGKLACVNKCTKGTKS------QMNCNL--------GTCQLQRS-GPRCLC 1794

Query: 1080 RVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHH 1131
                  WY G+ CE  +++ ++ GI  A +  LL+    +I  F  + +  H
Sbjct: 1795 PNTNTHWYWGETCEFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQRKRH 1846



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 67/307 (21%), Positives = 112/307 (36%), Gaps = 51/307 (16%)

Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455
           +S++  + P S     F  +   P   +  T   SS  P D +  P S T       S L
Sbjct: 150 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 203

Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515
           G          P      S P   E + L  ++    +L+  +PV S  R+  + L   G
Sbjct: 204 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 253

Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575
             +     +  +  S PSS  T+P P  T  +  +   +   SP   SSIP      T+ 
Sbjct: 254 --STTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 302

Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635
           +  +   S       +E+   +    GS        + +P S+T+S +  E  +      
Sbjct: 303 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 351

Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695
             ++  A      LV        +  S HS       +THFP+    SG +    A  ++
Sbjct: 352 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSS 403

Query: 696 ESASLTL 702
           + A+ T+
Sbjct: 404 QDATGTI 410



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 46/183 (25%), Positives = 72/183 (39%), Gaps = 18/183 (9%)

Query: 416  TFQAAWPSADESI------TSSIPPLDFSS-GPPSATGRELWSESPLGDLVSTHKLAFPS 468
            TFQ+ WPS+ +++      TS+   L  +S G PS+T    +S S      ST       
Sbjct: 1318 TFQS-WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS------STTLGRSEE 1370

Query: 469  KMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPV-ASEERTSGSHLVEDGLANVEESEDFLS 527
               + SSP     +     S T  +++      +S   T   H  E   A+    E   S
Sbjct: 1371 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE---S 1427

Query: 528  IDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLP 587
              S  S++ T   P  T  ++ +   S  SSP   ++  F   S TS   ++   S   P
Sbjct: 1428 RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP 1487

Query: 588  DAS 590
            D +
Sbjct: 1488 DTN 1490


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/90 (35%), Positives = 38/90 (42%), Gaps = 9/90 (10%)

Query: 1009 DEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068
            D  NPC+ + C   + C+  P SG   C+C PGY           C  QP  C N G C 
Sbjct: 929  DHVNPCESRPCQNGATCMAQP-SGYL-CQCAPGYDGQNCSKELDACQSQP--CHNHGTCT 984

Query: 1069 IMPGHGAICRCRVGENWWYRGKHCEEFVSE 1098
              PG G  C C  G    + G  CE  V E
Sbjct: 985  PKPG-GFHCACPPG----FVGLRCEGDVDE 1009



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 31/99 (31%), Positives = 39/99 (39%), Gaps = 12/99 (12%)

Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQ---PDFCLNDGKCDIM 1070
            C  Q C+  ++C  NP +G   C C PGY           C +    P  C + G C   
Sbjct: 396  CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455

Query: 1071 PGHGAICRCRVGENWWYRGKHCE----EFVSEPVIIGIT 1105
            PG    C C  G    Y G  CE    E +S+P   G T
Sbjct: 456  PG-SFNCLCPPG----YTGSRCEADHNECLSQPCHPGST 489



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 12/79 (15%)

Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPG----YLSVEERPCQSLCDLQPDFCLNDG 1065
            + + C  Q C+       +  +    C+C PG    +  VE  PC S    QP  C + G
Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS----QP--CFHGG 1059

Query: 1066 KCDIMPGH--GAICRCRVG 1082
             C+   G   G IC C  G
Sbjct: 1060 TCEATAGSPLGFICHCPKG 1078



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 9/68 (13%)

Query: 1028 NPWSGEAKCRCFPGYLSVEERPCQSLCD--LQPDFCLNDGKCDIMPGHGAICRCRVGENW 1085
            +P +    C C PG+    ER CQ+  +    P FC   G+C I       C C  G   
Sbjct: 95   SPLTPSFLCTCLPGFTG--ER-CQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG--- 148

Query: 1086 WYRGKHCE 1093
             + G+ C+
Sbjct: 149  -WTGEQCQ 155


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
            [Homo sapiens]
          Length = 1063

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%)

Query: 909  NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966
            +  FS DL +  S  Y+   + F   +     +++ GF  + +EIL+ RNGSIVV+  + 
Sbjct: 771  DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 829

Query: 967  FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022
                  P         LE        T+   +   S D  S  ++    F+      N  
Sbjct: 830  LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 881

Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070
            S+  + P   EA CR           FP   +   R C + C    D  ++   G+C ++
Sbjct: 882  SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 936

Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119
               G  CRC   +  W+ G  CE  V    ++G   A    L+++  A+
Sbjct: 937  ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 985


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%)

Query: 909  NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966
            +  FS DL +  S  Y+   + F   +     +++ GF  + +EIL+ RNGSIVV+  + 
Sbjct: 1194 DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 1252

Query: 967  FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022
                  P         LE        T+   +   S D  S  ++    F+      N  
Sbjct: 1253 LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 1304

Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070
            S+  + P   EA CR           FP   +   R C + C    D  ++   G+C ++
Sbjct: 1305 SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 1359

Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119
               G  CRC   +  W+ G  CE  V    ++G   A    L+++  A+
Sbjct: 1360 ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 1408



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 96/481 (19%), Positives = 166/481 (34%), Gaps = 55/481 (11%)

Query: 169 LTYAKETVSSSELSSPV--PVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNE 226
           +T    T+S S  +S    P   TST+ D+T  + +        ++E+SL     S+   
Sbjct: 318 VTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTT 377

Query: 227 IENVIEEATKPAGEQIA---EFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTG 283
                E AT P    +    E S H         +  + + H        I+  E     
Sbjct: 378 -----ETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHS 432

Query: 284 LPGYKEIRVLEFRSPKENDSGVDVYYAVTFNGEAISNTTWDLIS-LHSNKVENHGLVELD 342
            P +       F + K        + ++    E  S++T    S + + +  +H      
Sbjct: 433 TPRFTS----SFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFT 488

Query: 343 DKPTVVYTIS-NFRDYIA-----ETLQQNFLLGNSSL-------NPDPDSLQLINVRGVL 389
              T   T S N R + +     ET   +     SS+       +  P     I      
Sbjct: 489 SSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETP 548

Query: 390 RHQTEDLV-W-NTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSS-GPPSATG 446
            H T  L  W  T  ++   TP      T       +    TSSI   + +S   PS + 
Sbjct: 549 LHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSS 608

Query: 447 RELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERT 506
             ++S       VST   A  S    S +       ++T   VTP+ L T +P  S    
Sbjct: 609 STIYST------VSTSTTAITSHFTTSET-------AVTPTPVTPSSLSTDIPTTSLRTL 655

Query: 507 SGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIP 566
           + S +      ++  + DF SI   P+   T P     I S      + TSS   T+S  
Sbjct: 656 TPSSVGTS--TSLTTTTDFPSI---PTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPT 710

Query: 567 FGLDSLTSKVKDQLKVSPF------LPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS 620
                +T ++ +   +S F      +P+   +   +     G+ +      +T+  +++S
Sbjct: 711 MSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFGSTDSS 770

Query: 621 S 621
           +
Sbjct: 771 T 771


>gi|169170721 PREDICTED: similar to intestinal mucin [Homo sapiens]
          Length = 310

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%)

Query: 909  NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966
            +  FS DL +  S  Y+   + F   +     +++ GF  + +EIL+ RNGSIVV+  + 
Sbjct: 18   DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 76

Query: 967  FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022
                  P         LE        T+   +   S D  S  ++    F+      N  
Sbjct: 77   LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 128

Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070
            S+  + P   EA CR           FP   +   R C + C    D  ++   G+C ++
Sbjct: 129  SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 183

Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119
               G  CRC   +  W+ G  CE  V    ++G   A    L+++  A+
Sbjct: 184  ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 232


>gi|24430141 fibrillin 1 precursor [Homo sapiens]
          Length = 2871

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 27/120 (22%)

Query: 984  EDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNP----------WSGE 1033
            E FCT +  +       Y    + G    P + ++C +  EC  NP            GE
Sbjct: 1209 ETFCTNSEGS-------YECSCQPGFALMPDQ-RSCTDIDECEDNPNICDGGQCTNIPGE 1260

Query: 1034 AKCRCFPGYLSVEE-RPCQSL--CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGK 1090
             +C C+ G+++ E+ + C  +  CDL P+ CL+ G C+   G   IC C +G    Y GK
Sbjct: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKG-SFICHCDMG----YSGK 1314


>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
          Length = 236

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 7/101 (6%)

Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMP 1071
            +PC+   C     C+     G+A CRC  G+   + +   S        CLN G C ++ 
Sbjct: 27   DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLS 86

Query: 1072 GHGAICRCRVGENWWYRGKHC---EEFVSEPVIIGITIASV 1109
                 C C+VG    + GK C   +  +S P   G T  +V
Sbjct: 87   RDTYECTCQVG----FTGKECQWTDACLSHPCANGSTCTTV 123


>gi|148833508 notch1 preproprotein [Homo sapiens]
          Length = 2555

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073
            C    CNE S C  NP +G+A C C  GY           C L  + C + GKC    G 
Sbjct: 376  CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLG- 434

Query: 1074 GAICRCRVGENWWYRGKHCEEFVSEPV 1100
               C+C  G    Y G  CE  V+E V
Sbjct: 435  SFECQCLQG----YTGPRCEIDVNECV 457



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 9/89 (10%)

Query: 1006 ESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDG 1065
            +S  +A+PC    C    +CL  P+     C C P +     R   + C  +P  C + G
Sbjct: 136  KSCQQADPCASNPCANGGQCL--PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGG 193

Query: 1066 KCDIMPG-HGAICRCRVGENWWYRGKHCE 1093
             C    G +  +CR        + G +CE
Sbjct: 194  TCHNEVGSYRCVCRAT------HTGPNCE 216



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 13/90 (14%)

Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRC-----FPGYLSVEERPCQSLCDLQPDFCLND 1064
            + NPC    C     C V    G A   C     F G L +   P  + C   P  C N 
Sbjct: 59   DPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--PLDNACLTNP--CRNG 114

Query: 1065 GKCDIMPGHGAICRCRVGENWWYRGKHCEE 1094
            G CD++      CRC  G    + GK C++
Sbjct: 115  GTCDLLTLTEYKCRCPPG----WSGKSCQQ 140



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 9/89 (10%)

Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDI 1069
            + N C    C   + CL     GE +C C PGY  V        C   P  CL++G+C +
Sbjct: 452  DVNECVSNPCQNDATCLDQ--IGEFQCICMPGYEGVHCEVNTDECASSP--CLHNGRC-L 506

Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSE 1098
               +   C C  G    + G  C+  V E
Sbjct: 507  DKINEFQCECPTG----FTGHLCQYDVDE 531


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 9/85 (10%)

Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073
            C+ Q C     C  +       C C PG   V+ R C+ L    P+ C + G+C+  PG 
Sbjct: 738  CESQPCRAGGTCSSDGMGFH--CTCPPG---VQGRQCELLSPCTPNPCEHGGRCESAPGQ 792

Query: 1074 GAICRCRVGENWWYRGKHCEEFVSE 1098
              +C C  G    ++G  C++ V E
Sbjct: 793  LPVCSCPQG----WQGPRCQQDVDE 813



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073
            C    C+E + C  NP +G A C C PG+           C +  + C + G+C    G 
Sbjct: 355  CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQG- 413

Query: 1074 GAICRCRVGENWWYRGKHCEEFVSE 1098
              +C+C  G    Y G  CE  V+E
Sbjct: 414  SFLCQCGRG----YTGPRCETDVNE 434



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 15/85 (17%)

Query: 1017 QACNEFSECLVNPWS--------GEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068
            +   +  ECL NP              C C PGY        Q L D  P  C N G C 
Sbjct: 883  RCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCE--QDLPDCSPSSCFNGGTC- 939

Query: 1069 IMPGHGAICRCRVGENWWYRGKHCE 1093
            +   +   C CR G    Y G HC+
Sbjct: 940  VDGVNSFSCLCRPG----YTGAHCQ 960



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 1036 CRCFPGYLSVEERPCQSLCDLQPDFCLNDGKC-DIMPGHGAICRCRVGENWWYRGKHCEE 1094
            C+C P +           C LQP+ C N G C + + GH  +C      N W  G+ C +
Sbjct: 260  CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC-----VNGW-TGESCSQ 313

Query: 1095 FVSE 1098
             + +
Sbjct: 314  NIDD 317


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%)

Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
           G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 161 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 211

Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
           + S P   D +  P S T      ES        STH   FP     ++S  ++E S+  
Sbjct: 212 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 267

Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
           +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 268 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 313

Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
            +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 314 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 358


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%)

Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428
           G++     PDS       G+ RH T      T  SS  +T +++L  +   + PS + + 
Sbjct: 55  GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 105

Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485
           + S P   D +  P S T      ES        STH   FP     ++S  ++E S+  
Sbjct: 106 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 161

Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545
           +HS T +   T  P +S            GL    ES  F    + P+S+ T P P  T 
Sbjct: 162 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 207

Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590
            +  +   +   SP  T +  F   S TS   ++  +    PDAS
Sbjct: 208 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 252


>gi|194328809 latent transforming growth factor beta binding protein 3
            isoform 1 [Homo sapiens]
          Length = 1303

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 1001 YSLDVESGDEA----NPC-KFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERP--CQSL 1053
            Y L V +G  +    N C K   C +   C+  P  G  KC C+PGY     RP  C+ +
Sbjct: 647  YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP--GHYKCNCYPGYRLKASRPPVCEDI 704

Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVG 1082
             + +      DGKC+  PG      C+ G
Sbjct: 705  DECRDPSSCPDGKCENKPGSFKCIACQPG 733



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 6/100 (6%)

Query: 1002 SLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSL--CDLQPD 1059
            S D    ++ + C F A     +C+    +G  +C C  G+  V  R CQ +  C   P 
Sbjct: 818  SRDRSHCEDIDECDFPAACIGGDCINT--NGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875

Query: 1060 FCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEP 1099
             CL  G C  + G   +C C  G         CEE V +P
Sbjct: 876  LCLPHGACKNLQG-SYVCVCDEGFTPTQDQHGCEE-VEQP 913


>gi|18497288 latent transforming growth factor beta binding protein 3
            isoform 2 [Homo sapiens]
          Length = 1256

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 1001 YSLDVESGDEA----NPC-KFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERP--CQSL 1053
            Y L V +G  +    N C K   C +   C+  P  G  KC C+PGY     RP  C+ +
Sbjct: 647  YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP--GHYKCNCYPGYRLKASRPPVCEDI 704

Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVG 1082
             + +      DGKC+  PG      C+ G
Sbjct: 705  DECRDPSSCPDGKCENKPGSFKCIACQPG 733



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 6/100 (6%)

Query: 1002 SLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSL--CDLQPD 1059
            S D    ++ + C F A     +C+    +G  +C C  G+  V  R CQ +  C   P 
Sbjct: 818  SRDRSHCEDIDECDFPAACIGGDCINT--NGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875

Query: 1060 FCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEP 1099
             CL  G C  + G   +C C  G         CEE V +P
Sbjct: 876  LCLPHGACKNLQG-SYVCVCDEGFTPTQDQHGCEE-VEQP 913


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 164/783 (20%), Positives = 278/783 (35%), Gaps = 115/783 (14%)

Query: 402  SSSLQATPSSILDNTFQAA---WPSADESITSSIPPLDFSSGPPSA--TGRELWSESPL- 455
            S++   +PSSI    F A+   +  ++ES T    P+  ++ P  A  T   L  ES   
Sbjct: 1163 STTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAY 1222

Query: 456  -GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVED 514
                 ST  + FP     S   E     S T HS T   +       S   ++ S LVE+
Sbjct: 1223 HSSPGSTQTMHFPESSTASGRSE----ESRTSHSSTTHTI-------SSPPSTTSALVEE 1271

Query: 515  GLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVS--------LTSSPYLTSSIP 566
               +   S   ++    P SS T    +E+  S    D +         T+S  +  S  
Sbjct: 1272 P-TSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTT 1330

Query: 567  FGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAE 626
            F +      ++  L  +   P  S +  +++       S +  D    P S TSS  S E
Sbjct: 1331 FYISP--GSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGE 1382

Query: 627  PLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDD----RSTHFPEEEPL 682
            P S          L ++ E           +T  +S+ S   H       +T  P     
Sbjct: 1383 PTS----------LYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITT 1432

Query: 683  SGPAVPIFADTAAESASL-TLPKHISEVPGVDDYSVT--KAPLILTSVAISASTDKSDQA 739
            S  A       +   ++L T+    + VPG+ + S T   +P    + A S S   S   
Sbjct: 1433 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS--- 1489

Query: 740  DAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILA 799
              I  +      +S  +       ++   D+    T    S      T    + +   L 
Sbjct: 1490 --IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLV 1547

Query: 800  STPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQP------E 853
              P +   +  S T +T  P ++ ++ L +E        S     + T+  +       +
Sbjct: 1548 GEPTTF-YISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQ 1606

Query: 854  QVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFS 913
            + Q  NGK     +          +  ++P E  + L+ T       +  +++VT   F+
Sbjct: 1607 EGQIWNGKQCVCPQGYVGYQCLSPLE-SFPVETPEKLNAT-------LGMTVKVTYRNFT 1658

Query: 914  EDLFNKNSLEYKALEQRFLELLVPYLQS-NLTGFQNLEILNFRNGSIVVNSRM------- 965
            E + + +S EY+     F   +   L+  NL  ++ + I    NGSIVV + +       
Sbjct: 1659 EKMNDASSQEYQNFSTLFKNRMDVVLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYT 1718

Query: 966  --------KFANSVPPNVNNAVYMIL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEA 1011
                      A  V   + N     L   D C  A   Y+  +  +D     V  G D  
Sbjct: 1719 LEYEELFENLAEIVKAKIMNETRTTLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQ 1775

Query: 1012 NPCKFQACNEFSECL-VNPWSGEAKC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068
              C  +A   +++   V+   G+  C  +C  G  S      Q  C+L        G C 
Sbjct: 1776 EQCTQKAAEGYTQFYYVDVLDGKLACVNKCTKGTKS------QMNCNL--------GTCQ 1821

Query: 1069 IMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQ 1128
            +    G  C C      WY G+ CE  +++ ++ GI  A +  LL+    +I  F  + +
Sbjct: 1822 LQRS-GPRCLCPNTNTHWYWGETCEFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQR 1880

Query: 1129 AHH 1131
              H
Sbjct: 1881 KRH 1883



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 60/284 (21%), Positives = 92/284 (32%), Gaps = 31/284 (10%)

Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526
           P      SSP   + + L  ++ T  +L+   PV S   T   H      ++     +  
Sbjct: 283 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSS--TGSPHTTLSPASSTTHEGEPT 340

Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583
           +  S PSS  T P P  T  +      +  SSP  T +  F   S T   S+    +  S
Sbjct: 341 TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS 400

Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637
           P        P  S     + +      S      + +P S T+S  S E           
Sbjct: 401 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE----------- 449

Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEH---DDRSTHFPEEEPLSGPAVPIFADTA 694
               A              ST     H+ Y        +THF +   +SG +    A  +
Sbjct: 450 ---SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 506

Query: 695 AESASLTLPKHISEVPGVDDYSVTKAPL---ILTSVAISASTDK 735
           +  A  T        P V     T +P+    + + A+  ST K
Sbjct: 507 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK 550



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 67/307 (21%), Positives = 113/307 (36%), Gaps = 51/307 (16%)

Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455
           +S++  + P S     F  +   P   +  T   SS  P D +  P S T       S L
Sbjct: 584 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 637

Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515
           G          P      S P   E + L  ++    +L+  +PV S  R+  + L   G
Sbjct: 638 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 687

Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575
             +     +  +  S PSS+ T+P P  T  +  +   +   SP   SSIP      T+ 
Sbjct: 688 --STTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 736

Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635
           +  +   S       +E+   +    GS        + +P S+T+S +  E  +      
Sbjct: 737 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 785

Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695
             ++  A      LV        +  S HS       +THFP+    SG +    A  ++
Sbjct: 786 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESIASHSS 837

Query: 696 ESASLTL 702
           + A+ T+
Sbjct: 838 QDATGTI 844



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 100/493 (20%), Positives = 170/493 (34%), Gaps = 87/493 (17%)

Query: 403  SSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTH 462
            SS  +T S++++    +   S   + T+  P    +SG    +     S+   G +V   
Sbjct: 790  SSAPSTTSALVEEP-TSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPA 848

Query: 463  KLAFPSKMGLSSSPEV----LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLAN 518
            +      +G S++  +    +E ++L   + TP + +      S  R+  + L      +
Sbjct: 849  RSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 908

Query: 519  VEESEDFLSIDSLPSSSFTQPVP-KETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVK 577
               SE+  +  S P S+ T   P   T P +     +  SSP  T +      S T+ + 
Sbjct: 909  SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA-STTTXLV 967

Query: 578  DQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPLSKPWLE 634
             +   SP                + SGS +   L   P S T+   SEKS    S P   
Sbjct: 968  GEPTTSP----------------ISSGSTETTAL---PGSTTTAGLSEKSTTFYSSP-RS 1007

Query: 635  DDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTA 694
             D +L PA      +       S +  + HS+      +T FP    + G +      TA
Sbjct: 1008 PDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ---ESTA 1056

Query: 695  AESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESS 754
            + S+           PG  D +++      +S+   ++T  S                  
Sbjct: 1057 SHSS-----------PGSTDTTLSPRSTTASSLGPESTTFHSGPG--------------- 1090

Query: 755  NYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD---RLWLS 811
                  S  + + PD  T   +L  S  V + T S         ++T Q      + W S
Sbjct: 1091 ------STETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPS 1144

Query: 812  VTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSYVEMSTS 871
               +   PPTT S  +E           L     G+    P      +       E ST+
Sbjct: 1145 SKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSIPTTHFSASSTTFGRSEESTT 1193

Query: 872  VHSTEMVSVAWPT 884
            VHS+ +     P+
Sbjct: 1194 VHSSPVAPATTPS 1206


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 164/765 (21%), Positives = 261/765 (34%), Gaps = 122/765 (15%)

Query: 174 ETVSSSELSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERP-EESISNEIENVIE 232
           E    S L  PV    +STL     S P      +EG  +S L+ P   S S+ + ++ +
Sbjct: 156 EGFPQSVLQIPVSAASSSTLVSIFQSSPESTQSPFEGFPQSPLQIPVSRSFSSTLLSIFQ 215

Query: 233 ---EATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGL----- 284
              E T+   E  A+  + +        +  SSS     L + F    ++ F G      
Sbjct: 216 SSPERTQSTFEGFAQSPLQI-------PVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSL 268

Query: 285 -----PGYKEIRVLEFR-SPKENDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVE-NHG 337
                P +    V  F+ SP+   S  + +          S+++  L+SL  +  E  H 
Sbjct: 269 QIPVSPSFSSTLVSLFQSSPERTQSTFEGFPQSPLQIPVSSSSSSTLLSLFQSSPERTHS 328

Query: 338 LVE-LDDKPTVVYTISNFRDYIAETLQQNFLLGNSSLNPDPDS-LQ----------LINV 385
             E        +   S+F   +    Q +     S+    P S LQ          L+++
Sbjct: 329 TFEGFPQSLLQIPMTSSFSSTLLSIFQSSPESAQSTFEGFPQSPLQIPGSPSFSSTLLSL 388

Query: 386 RGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSAT 445
                 +T         S LQ   +S   +T  +   S+ ES  S+     F   P    
Sbjct: 389 FQSSPERTHSTFEGFPQSPLQIPMTSSFSSTLLSILQSSPESAQSAFE--GFPQSPLQIP 446

Query: 446 GRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSS-------LTLHSVTPAVLQT-- 496
               +S + L    S+ +    +  G   SP  + VSS       L+L   +P   Q+  
Sbjct: 447 VSSSFSYTLLSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQSTF 506

Query: 497 -GLPVA------SEERTSGSHLVEDGLANVEESEDFLSIDSLPSS------SFTQPVPKE 543
            G P +      S      +H     + ++ E ED LS    P S      S +     +
Sbjct: 507 EGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHYFPQ 566

Query: 544 TIPSMEDSDVSLTSSPYLTSSIPFGLDSLT------SKVKDQLKVSP-FLPDASMEKELI 596
           + P  EDS      SP+     P G DSL+      S  + +  +SP + P + ++ E  
Sbjct: 567 SPPQGEDS-----LSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGE-E 620

Query: 597 FDGGLGS------------------------GSGQKVDLITWPWSETSSEKSAEPLSKPW 632
           F   L S                          G     +  P S      S  PL  P 
Sbjct: 621 FQSSLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPE 680

Query: 633 L--EDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPE-----EEPLSGP 685
              E +DSL P +I    L   D + S        ++E      HFP+     E+  S  
Sbjct: 681 SAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSL 740

Query: 686 AVPIFADTAAESASLTLPKHISEVPGVDDYSVTKAPL-----ILTSVAISASTDKSDQAD 740
             P+     + S SL+LP+   E P        ++PL        S  +++    S ++ 
Sbjct: 741 QSPV--SICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESP 798

Query: 741 AILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILAS 800
               E   Q    S    F S  S       +L    P S    + +SSL K S +    
Sbjct: 799 QSPPEGPAQSPLQSPVSSFPSSTS------SSLSQSSPVSSFPSSTSSSLSKSSPESPLQ 852

Query: 801 TPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRI 845
           +P       +S + ST L P +  +    +      D  LE D +
Sbjct: 853 SPV------ISFSSSTSLSPFSEESSSPVDEYTSSSDTLLESDSL 891


>gi|153070262 meprin A alpha [Homo sapiens]
          Length = 746

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLL 1113
            CD  P  C NDG C  + G  A CRC  G  ++Y G+ C+       ++G+ I    G++
Sbjct: 674  CDPNP--CQNDGICVNVKGM-ASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVI 730

Query: 1114 VIFSAII 1120
             +  +II
Sbjct: 731  FLTFSII 737


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 13/79 (16%)

Query: 1017 QACNEFSECLVNPWSGEAKC-RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGA 1075
            + C+E   CL  P      C RC PGY       CQ+ C   P      G  D + G G 
Sbjct: 597  EGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPN--CQA-CTCDPR-----GALDQLCGAGG 648

Query: 1076 ICRCRVGENWWYRGKHCEE 1094
            +CRCR G    Y G  C+E
Sbjct: 649  LCRCRPG----YTGTACQE 663


>gi|7019499 peroxisome proliferator-activated receptor gamma,
            coactivator 1 alpha [Homo sapiens]
          Length = 798

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 1133 RSERESPFSGS-SRQPDSLSSIENAVKYNPVYESHRAGCE-------KYEGPYPQHPFYS 1184
            RS   SP+S S SR P S SS  +   Y   +  HR           +   PY + P Y 
Sbjct: 576  RSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYD 635

Query: 1185 SASGDVIGGLSREEIRQMYESSELSREEIQERMR 1218
            S        L REE R+ YE  E  R + +ER R
Sbjct: 636  SYEEYQHERLKREEYRREYEKRESERAKQRERQR 669


>gi|122937283 6720455I24Rik homolog [Homo sapiens]
          Length = 1413

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 14/82 (17%)

Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQ-SLCDLQPDFCLNDGKC-DI 1069
            +PC  + C    +C V   +G A C C  GY       C+  + D  PD CLN G C D+
Sbjct: 351  SPCDTKECQHGGQCQVE--NGSAVCVCQAGYTGAA---CEMDVDDCSPDPCLNGGSCVDL 405

Query: 1070 MPGHGAIC-------RCRVGEN 1084
            +  +  +C       RC  G++
Sbjct: 406  VGNYTCLCAEPFKGLRCETGDH 427


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,012,059
Number of Sequences: 37866
Number of extensions: 2269230
Number of successful extensions: 6046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 5728
Number of HSP's gapped (non-prelim): 426
length of query: 1241
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1127
effective length of database: 13,930,794
effective search space: 15700004838
effective search space used: 15700004838
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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