BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens] (1241 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens] 2477 0.0 gi|6631090 interphotoreceptor matrix proteoglycan 1 [Homo sapiens] 213 1e-54 gi|91982772 mucin 17 [Homo sapiens] 65 3e-10 gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ... 65 5e-10 gi|153070264 meprin A beta [Homo sapiens] 53 2e-06 gi|239745235 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-05 gi|239756347 PREDICTED: similar to taste receptor protein 1 [Hom... 48 5e-05 gi|239750872 PREDICTED: similar to taste receptor protein 1 [Hom... 48 5e-05 gi|83367077 mucin 16 [Homo sapiens] 47 9e-05 gi|24041035 notch 2 preproprotein [Homo sapiens] 46 3e-04 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 45 3e-04 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 45 3e-04 gi|55770876 notch4 preproprotein [Homo sapiens] 45 3e-04 gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti... 45 4e-04 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 45 4e-04 gi|169170721 PREDICTED: similar to intestinal mucin [Homo sapiens] 45 4e-04 gi|24430141 fibrillin 1 precursor [Homo sapiens] 45 6e-04 gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] 45 6e-04 gi|148833508 notch1 preproprotein [Homo sapiens] 44 0.001 gi|134244285 Notch homolog 3 [Homo sapiens] 43 0.002 gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 43 0.002 gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens] 43 0.002 gi|194328809 latent transforming growth factor beta binding prot... 42 0.003 gi|18497288 latent transforming growth factor beta binding prote... 42 0.003 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 42 0.003 gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 42 0.004 gi|153070262 meprin A alpha [Homo sapiens] 41 0.008 gi|21264602 laminin alpha 5 [Homo sapiens] 41 0.008 gi|7019499 peroxisome proliferator-activated receptor gamma, coa... 40 0.011 gi|122937283 6720455I24Rik homolog [Homo sapiens] 40 0.014 >gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens] Length = 1241 Score = 2477 bits (6419), Expect = 0.0 Identities = 1241/1241 (100%), Positives = 1241/1241 (100%) Query: 1 MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT 60 MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT Sbjct: 1 MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLAT 60 Query: 61 KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA 120 KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA Sbjct: 61 KKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEA 120 Query: 121 FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE 180 FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE Sbjct: 121 FRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSE 180 Query: 181 LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE 240 LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE Sbjct: 181 LSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGE 240 Query: 241 QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE 300 QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE Sbjct: 241 QIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKE 300 Query: 301 NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE 360 NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE Sbjct: 301 NDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAE 360 Query: 361 TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA 420 TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA Sbjct: 361 TLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAA 420 Query: 421 WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE 480 WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE Sbjct: 421 WPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLE 480 Query: 481 VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV 540 VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV Sbjct: 481 VSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPV 540 Query: 541 PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG 600 PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG Sbjct: 541 PKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGG 600 Query: 601 LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ 660 LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ Sbjct: 601 LGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQ 660 Query: 661 ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA 720 ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA Sbjct: 661 ISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKA 720 Query: 721 PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES 780 PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES Sbjct: 721 PLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPES 780 Query: 781 ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL 840 ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL Sbjct: 781 ERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISL 840 Query: 841 ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV 900 ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV Sbjct: 841 ELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALV 900 Query: 901 VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV 960 VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV Sbjct: 901 VFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIV 960 Query: 961 VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN 1020 VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN Sbjct: 961 VNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACN 1020 Query: 1021 EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR 1080 EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR Sbjct: 1021 EFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCR 1080 Query: 1081 VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF 1140 VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF Sbjct: 1081 VGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPF 1140 Query: 1141 SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR 1200 SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR Sbjct: 1141 SGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIR 1200 Query: 1201 QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV 1241 QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV Sbjct: 1201 QMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV 1241 >gi|6631090 interphotoreceptor matrix proteoglycan 1 [Homo sapiens] Length = 797 Score = 213 bits (541), Expect = 1e-54 Identities = 119/250 (47%), Positives = 163/250 (65%), Gaps = 17/250 (6%) Query: 834 GVQDISLELDRIG-TDYYQPEQVQEQNGKVG---SYVEMSTSVHSTEMVSVAWPTEGGDD 889 G +D+ LD + +D P +V E + V ++E +T V + + ++ + Sbjct: 511 GGEDMVRHLDEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTS-------S 563 Query: 890 LSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNL 949 ++ LVVFFSLRV NM FS DLFNK+SLEY+ALEQ+F +LLVPYL+SNLTGF+ L Sbjct: 564 MTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQL 623 Query: 950 EILNFRNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD 1009 EILNFRNGS++VNS+MKFA SVP N+ AV+ +LEDF + A ++L ID YSL++E D Sbjct: 624 EILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPAD 683 Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGK-CD 1068 +A+PCKF AC EF++C+ N + EA+CRC PGY S SL L+P C K C+ Sbjct: 684 QADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQ-----GSLDGLEPGLCGPGTKECE 738 Query: 1069 IMPGHGAICR 1078 ++ G GA CR Sbjct: 739 VLQGKGAPCR 748 Score = 163 bits (413), Expect = 8e-40 Identities = 132/515 (25%), Positives = 233/515 (45%), Gaps = 47/515 (9%) Query: 78 RRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYW 137 R +RS FP GVK+CP ES+ + + + Y+++RVCQEAVWEA+R F DR+P EY W Sbjct: 67 RTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDW 126 Query: 138 MNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSELSSPVPVGDTSTLGDTT 197 +++C+ +F++G NFS S EH L+ +++ E+S+ +G+ + Sbjct: 127 VSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPDRKDEISAEKTLGEPGETIVIS 186 Query: 198 LSVPHPEVDAYEGASESSLERPEESISNEI-ENVIEEATKPAGEQIAEF----------S 246 V + + + P++++ NEI +N + + P E+ EF S Sbjct: 187 TDVANVSLGPFP-------LTPDDTLLNEILDNTLNDTKMPTTERETEFAVLEEQRVELS 239 Query: 247 IHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKENDSGVD 306 + L+ ++++ EL DS S ++Q L + +++ F LPG+K+I VL FR KE D Sbjct: 240 VSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSS 299 Query: 307 VYYAVT-----FNGEAISNTTWDLISLHSNKVEN----HGLVELDDKPTVVYTISNFRDY 357 +T + EA S + DL+S SNK+E+ HG +E D +P + T ++ + Sbjct: 300 TEMQLTAIFKRHSAEAKSPAS-DLLSFDSNKIESEEVYHGTMEEDKQPEIYLTATDLKRL 358 Query: 358 IAETLQQNFLLGNSSLNPDPDSLQLIN-VRGVLRHQTEDLVWNTQSSSLQATPSSILDNT 416 I++ L++ L D ++Q + + G L D +S T + L Sbjct: 359 ISKALEEEQSL-------DVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPE 411 Query: 417 FQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSP 476 P + + D S PP+ L P S L ++ Sbjct: 412 LPPVEPQLETVDGAEHGLPDTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATD 471 Query: 477 EVLEVSSLTL-----HSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESE--DFLSID 529 + + V LT+ +++ L P AS + + S ED + +++E + D + Sbjct: 472 QTMLVPGLTIPTSDYSAISQLALGISHPPASSDDSRSSAGGEDMVRHLDEMDLSDTPAPS 531 Query: 530 SLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSS 564 +P S VP + + +++ Y+T+S Sbjct: 532 EVPELSEYVSVPDHFL----EDTTPVSALQYITTS 562 Score = 36.6 bits (83), Expect = 0.15 Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 2/111 (1%) Query: 189 DTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAG-EQIAEFSI 247 D L DT PE+ Y + LE + + P G E + FS+ Sbjct: 520 DEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTSSMTIAPKGRELVVFFSL 579 Query: 248 HLLGKQYREELQDSSSFHHQHLEEEFIS-EVENAFTGLPGYKEIRVLEFRS 297 + + +L + SS ++ LE++F V + L G+K++ +L FR+ Sbjct: 580 RVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQLEILNFRN 630 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 65.5 bits (158), Expect = 3e-10 Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 25/237 (10%) Query: 904 SLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNS 963 ++ VT++ F+E+L N +S E++ +Q F E + + S + + + I R GS+VV Sbjct: 4191 TVTVTSVKFTEELKNHSSQEFQEFKQTFTEQM-NIVYSGIPEYVGVNITKLRLGSVVVEH 4249 Query: 964 ----RMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQAC 1019 R K+ ++NA ++ E T T + I+ D+ C Sbjct: 4250 DVLLRTKYTPEYKTVLDNATEVVKEKI--TKVTTQQIMINDICSDMM-------CFNTTG 4300 Query: 1020 NEFSECLVNPWSGEAKCRC----FPGYLSVEERPCQSLC--DLQPDFCL----NDGKCDI 1069 + V + E CR + Y VE R + C +P F + N GKC Sbjct: 4301 TQVQNITVTQYDPEEDCRKMAKEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQ- 4359 Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRT 1126 M G C C E WY G+ C + + ++ G+ A VV +L+I A++ R+ Sbjct: 4360 MSLSGPQCLCVTTETHWYSGETCNQGTQKSLVYGLVGAGVVLMLIILVALLMLVFRS 4416 Score = 33.9 bits (76), Expect = 0.99 Identities = 92/439 (20%), Positives = 160/439 (36%), Gaps = 57/439 (12%) Query: 407 ATP-SSILDNTFQAAWPSADESITSSIPPLDF----------SSGPPSATGRELWSESPL 455 +TP +SIL +T A E+ T S P+D SS P +A G + +P Sbjct: 2927 STPLTSILVSTVPVA---GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTP- 2982 Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515 G+ + S M ++SS E S+L S TPA T + ++E +S + G Sbjct: 2983 GERRTPLTSMSVSTMPVASS----EASTL---SRTPADTSTPVTTSTEASSSPTTAEGTG 3035 Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLT----SSIPFGLDS 571 + SE + S+P S+ +P+ + S D ++SP +T SS P + Sbjct: 3036 IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD---SNSPVVTSTEVSSSPTPAEG 3092 Query: 572 LTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSET---SSEKSAEPL 628 + + + S L + + + + S VD T + T SS ++E Sbjct: 3093 TSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGT 3152 Query: 629 SKPWLEDDDSLLP-AEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAV 687 S P + P + +++V DST + ST G ++ Sbjct: 3153 SMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI 3212 Query: 688 PIFADTAAESASLTLPKHISEVP-GVDDYSVTKAPLILTSVAISASTDKSDQADAILRED 746 P T +E + +S P + S+ + ++ ++ ST+ S Sbjct: 3213 P--TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTS 3270 Query: 747 MEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD 806 M T S T T +P S T+++ L++TP Sbjct: 3271 MPTSTPSEG---------------STPLTSMPVS------TTTVASSETSTLSTTPADTS 3309 Query: 807 RLWLSVTQSTKLPPTTIST 825 + +Q++ PP T Sbjct: 3310 TPVTTYSQASSSPPIADGT 3328 Score = 31.6 bits (70), Expect = 4.9 Identities = 12/53 (22%), Positives = 29/53 (54%) Query: 244 EFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFR 296 E ++ + ++ EEL++ SS Q ++ F ++ ++G+P Y + + + R Sbjct: 4189 ELTVTVTSVKFTEELKNHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLR 4241 >gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) precursor [Homo sapiens] Length = 539 Score = 64.7 bits (156), Expect = 5e-10 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Query: 1031 SGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGK 1090 S E C G++ C+S+CDL P +C N G+C ++ GA CRC + W++G Sbjct: 352 SSENGTECRSGFVR-HNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGM 410 Query: 1091 HCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTL 1127 CE +++ ++ + + S +L++ + FF + L Sbjct: 411 RCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKL 447 >gi|153070264 meprin A beta [Homo sapiens] Length = 701 Score = 52.8 bits (125), Expect = 2e-06 Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Query: 1045 VEERPCQSLCDL-QPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIG 1103 ++ P S+ DL C NDG C + G A CRC+ GE+WWY G+ CE+ S I Sbjct: 596 IQLTPAPSVQDLCSKTTCKNDGVCTVRDGK-AECRCQSGEDWWYMGERCEKRGSTRDTIV 654 Query: 1104 ITIASVVGLLVIFSAI 1119 I ++S V + + I Sbjct: 655 IAVSSTVAVFALMLII 670 >gi|239745235 PREDICTED: hypothetical protein [Homo sapiens] Length = 664 Score = 49.7 bits (117), Expect = 2e-05 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 7/151 (4%) Query: 888 DDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQ 947 D +S T + + +TN FS L N S +++ L + L P GFQ Sbjct: 210 DSVSSTPGPSHMTRSVTFTITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQ 269 Query: 948 NLEILNFRNGSIVVNSRMKFANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVE 1006 + +L FR GS+ VN+ + F P P+ ++ + T+ + NL++ + SL + Sbjct: 270 GIGVLVFRPGSVAVNASLVFGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSD 329 Query: 1007 SGD------EANPCKFQACNEFSECLVNPWS 1031 D E +F A F L+ P S Sbjct: 330 GADLITLARETISIRFTAMRSFLPQLLVPGS 360 >gi|239756347 PREDICTED: similar to taste receptor protein 1 [Homo sapiens] Length = 562 Score = 48.1 bits (113), Expect = 5e-05 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 7/132 (5%) Query: 907 VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMK 966 +TN FS L N S +++ L + L P GFQ + +L FR GS+ VN+ + Sbjct: 9 ITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQGIGVLVFRPGSVAVNASLV 68 Query: 967 FANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD------EANPCKFQAC 1019 F P P+ ++ + T+ + NL++ + SL + D E +F A Sbjct: 69 FGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSDGADLITLARETISIRFTAM 128 Query: 1020 NEFSECLVNPWS 1031 F L+ P S Sbjct: 129 RSFLPQLLVPGS 140 >gi|239750872 PREDICTED: similar to taste receptor protein 1 [Homo sapiens] Length = 562 Score = 48.1 bits (113), Expect = 5e-05 Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 7/132 (5%) Query: 907 VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMK 966 +TN FS L N S +++ L + L P GFQ + +L FR GS+ VN+ + Sbjct: 9 ITNEAFSAALLNPASWKHQLLRKIIHHQLQPLYHEAFPGFQGIGVLVFRPGSVAVNASLV 68 Query: 967 FANSVP-PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGD------EANPCKFQAC 1019 F P P+ ++ + T+ + NL++ + SL + D E +F A Sbjct: 69 FGGRAPGPSPCELLWALYRKVKTSGHMLGNLSLAENSLTSDGADLITLARETISIRFTAM 128 Query: 1020 NEFSECLVNPWS 1031 F L+ P S Sbjct: 129 RSFLPQLLVPGS 140 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 47.4 bits (111), Expect = 9e-05 Identities = 144/644 (22%), Positives = 229/644 (35%), Gaps = 78/644 (12%) Query: 398 WNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSG------PPSATGRELWS 451 W T + T S + N +A +TS P +D SG PPS G Sbjct: 11577 WLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTS--PGVDTRSGVPTTTIPPSIPGVVTSQ 11634 Query: 452 ESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHL 511 + ST A P+ PE T S T QTG V RT S Sbjct: 11635 VTSSATDTST---AIPTLTPSPGEPET------TASSATHPGTQTGFTVPI--RTVPSSE 11683 Query: 512 VEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDS 571 + + V + S +SSF+ P T P M S + SS LT+ P + Sbjct: 11684 PDTMASWVTHPPQTSTPVSRTTSSFSHSSPDAT-PVMATSPRTEASSAVLTTISPGAPEM 11742 Query: 572 LTSKVKDQ-LKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEP 627 +TS++ S +P + + L S + T+P S SE +A Sbjct: 11743 VTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASL 11802 Query: 628 LSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEP-LSGPA 686 +P E +L P + L+ S +S P P +S Sbjct: 11803 TIRPGAETSTAL-PTQTTSSLFTLLVTGTSRVDLS--------------PTASPGVSAKT 11847 Query: 687 VPIFADTAAESASL----TLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAI 742 P+ E++++ TL + E G+ S + A +++ ++ S S + A Sbjct: 11848 APLSTHPGTETSTMIPTSTLSLGLLETTGLLATS-SSAETSTSTLTLTVSPAVSGLSSAS 11906 Query: 743 LREDMEQITESSNYEWFDSEVSMVKPDMQ-----TLWTILPESERVWTRTSSLEKLS-RD 796 + D Q S N E S S+ P+ T T++P +TS E +S Sbjct: 11907 ITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTT 11966 Query: 797 ILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIM-----GVQDISLELDRIGTDYYQ 851 IL +T A L + + T TT L + G+ ++ E T Y Sbjct: 11967 ILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNH 12026 Query: 852 PEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLR--VTN 909 + + Y +TS T S T S T + +V F+L +TN Sbjct: 12027 RSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIP--SSTAATVPFMVPFTLNFTITN 12084 Query: 910 MMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSI-VVNSRMKFA 968 + + ED+ + S ++ A E+ LL P FRN S+ + S + A Sbjct: 12085 LQYEEDMRHPGSRKFNATERELQGLLKPL---------------FRNSSLEYLYSGCRLA 12129 Query: 969 NSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEAN 1012 + P ++A ++ CT + +L +D+ L E + N Sbjct: 12130 SLRPEKDSSAT--AVDAICTHRPDPEDLGLDRERLYWELSNLTN 12171 Score = 36.6 bits (83), Expect = 0.15 Identities = 106/532 (19%), Positives = 185/532 (34%), Gaps = 72/532 (13%) Query: 413 LDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGL 472 LD + A+W +T P + ++ +T W P + S+ P Sbjct: 5878 LDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVP----- 5932 Query: 473 SSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLP 532 P + SSL +V+ + + LPV S TSG D L ++ L SLP Sbjct: 5933 --LPAITSHSSL-YSAVSGSSPTSALPVTS-LLTSGRRKTIDML----DTHSELVTSSLP 5984 Query: 533 SSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKV--------SP 584 S+S E + S ++ T+ G + K+ + + P Sbjct: 5985 SAS---SFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPP 6041 Query: 585 FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEI 644 + + ME ++ GS + VD S PL+ ED +L+ Sbjct: 6042 KVTGSMMEDAIVSTSTPGSPETKNVD-----------RDSTSPLTPELKEDSTALVMNST 6090 Query: 645 EDKKLVLVD-KMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLP 703 + V +D+ ++S+ +D + S P + + + S LT+ Sbjct: 6091 TESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTIS 6150 Query: 704 KHISEVPGVDDYSVT---KAPLILTSVAISASTDKSDQAD-------AILREDMEQITES 753 H + VT + L +++A SA T + D +++ D+ + ++ Sbjct: 6151 THKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKT 6210 Query: 754 SNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVT 813 S + E + + L T P TS+L++ S L S +T Sbjct: 6211 SPFS--AEEANSLSSQAPLLVTTSPSPV-----TSTLQEHSTSSLVSVTSVPTPTLAKIT 6263 Query: 814 -QSTKLPPTTIS------TLLEDEVIMGVQ----DISLELDRIGT-----DYYQPEQVQE 857 T L P T S TL E I+ + +GT ++Y Sbjct: 6264 DMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDS 6323 Query: 858 QNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTN 909 K S V + TS +VS + P ++T+ +L+ F LR T+ Sbjct: 6324 DPYKATSAV-VITSTSGDSIVSTSMPRSSAMKKIESETTFSLI--FRLRETS 6372 Score = 33.9 bits (76), Expect = 0.99 Identities = 52/211 (24%), Positives = 86/211 (40%), Gaps = 26/211 (12%) Query: 404 SLQATPSSILDNTFQAAWPSADESITSSIPP-----LDFSSGPPSATGRELWSESPLGDL 458 SL T S + +T + PS+ S+TS + P D S+ P ++ L S + + L Sbjct: 10026 SLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNL-SGTSVEIL 10084 Query: 459 VSTHKLAFPSKMGLSSSPEVLEV----------SSLTLHS-VTPAVLQTGLPVASEERTS 507 ++ K+ SSS V V SS+++HS + A G P + E + Sbjct: 10085 AASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSI 10144 Query: 508 GSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPF 567 + + + E+E F + +S F ++T S++ S V+ T++P S Sbjct: 10145 STSMPANFETTGFEAEPFSHL----TSGF-----RKTNMSLDTSSVTPTNTPSSPGSTHL 10195 Query: 568 GLDSLTSKVKDQLKVSPFLPDASMEKELIFD 598 S T SP P AS E+ D Sbjct: 10196 LQSSKTDFTSSAKTSSPDWPPASQYTEIPVD 10226 Score = 31.2 bits (69), Expect = 6.4 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 2/53 (3%) Query: 895 TSGALVVFFSLR--VTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTG 945 T+G L+V F+L +TN+ + ED+ S ++ E+ LL P ++ G Sbjct: 12538 TAGPLLVLFTLNFTITNLKYEEDMHRPGSRKFNTTERVLQTLLGPMFKNTSVG 12590 >gi|24041035 notch 2 preproprotein [Homo sapiens] Length = 2471 Score = 45.8 bits (107), Expect = 3e-04 Identities = 33/129 (25%), Positives = 48/129 (37%), Gaps = 7/129 (5%) Query: 984 EDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYL 1043 E C T +N E +PC+ C C+ G+A CRC G+ Sbjct: 38 EGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT 97 Query: 1044 SVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHC---EEFVSEPV 1100 + + S CLN G C ++ C C+VG + GK C + +S P Sbjct: 98 GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG----FTGKECQWTDACLSHPC 153 Query: 1101 IIGITIASV 1109 G T +V Sbjct: 154 ANGSTCTTV 162 Score = 42.7 bits (99), Expect = 0.002 Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 26/156 (16%) Query: 955 RNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLA-----IDKYSLDVESGD 1009 +NG ++ F S PP + D C + +N I YS G Sbjct: 1197 QNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256 Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFP---GYLSV-----EERPCQSLCDLQPDF- 1060 C+ + +ECL NP S E C YL V R C++ D+ P Sbjct: 1257 AGERCE----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMP 1312 Query: 1061 CLNDGKCDI---MPGHGAICRCRVGENWWYRGKHCE 1093 CLN G C + MP G ICRC G + G C+ Sbjct: 1313 CLNGGTCAVASNMP-DGFICRCPPG----FSGARCQ 1343 Score = 37.0 bits (84), Expect = 0.12 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 16/89 (17%) Query: 1011 ANPCKFQA-CNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDI 1069 +NPC+ A C++F G +C C PGY V C QP C N G C Sbjct: 1155 SNPCQHGATCSDFI--------GGYRCECVPGYQGVNCEYEVDECQNQP--CQNGGTCID 1204 Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSE 1098 + H C C G RG CEE + + Sbjct: 1205 LVNHFK-CSCPPGT----RGLLCEENIDD 1228 Score = 34.7 bits (78), Expect = 0.58 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 13/79 (16%) Query: 1036 CRCFPGYLSVEERPCQSLCDLQPDFCLNDGKC-DIMPGHGAICRCRVGENWWYRGKHCE- 1093 C C PGY+ C P CLNDG+C D++ G+ C C+ G + G +CE Sbjct: 593 CICNPGYMGAICSDQIDECYSSP--CLNDGRCIDLVNGYQ--CNCQPGTS----GVNCEI 644 Query: 1094 ---EFVSEPVIIGITIASV 1109 + S P I GI + + Sbjct: 645 NFDDCASNPCIHGICMDGI 663 Score = 33.1 bits (74), Expect = 1.7 Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 7/86 (8%) Query: 1013 PCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPG 1072 PC C + C +P C C PG+ C +P C+N G C G Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP--CMNHGLCHNTQG 893 Query: 1073 HGAICRCRVGENWWYRGKHCEEFVSE 1098 +C C G + G CEE + + Sbjct: 894 -SYMCECPPG----FSGMDCEEDIDD 914 Score = 32.7 bits (73), Expect = 2.2 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 6/86 (6%) Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDL-QPDFCLNDGKCDIMPG 1072 C C++ + C NP +G+ C C GY + C + + C + GKC G Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438 Query: 1073 HGAICRCRVGENWWYRGKHCEEFVSE 1098 C C G Y G CE ++E Sbjct: 439 -AFHCECLKG----YAGPRCEMDINE 459 Score = 32.7 bits (73), Expect = 2.2 Identities = 30/112 (26%), Positives = 41/112 (36%), Gaps = 19/112 (16%) Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPG----YLSVEERPCQSLCD----LQPDFCLN 1063 N C C C+ E++C C G Y V C L C + Sbjct: 1065 NLCSRSPCKNKGTCVQK--KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQH 1122 Query: 1064 DGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSE----PVIIGITIASVVG 1111 G C I G+ C+C +G Y G +CEE + E P G T + +G Sbjct: 1123 SGVC-INAGNTHYCQCPLG----YTGSYCEEQLDECASNPCQHGATCSDFIG 1169 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 45.4 bits (106), Expect = 3e-04 Identities = 106/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%) Query: 401 QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460 +SS+ + P S T A+P +S T+S D S P ++ + +E+ L + Sbjct: 1467 ESSTSHSQPGS----THTTAFP---DSTTTS----DLSQEPTTSHSSQGSTEATLSPGST 1515 Query: 461 THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520 T SSP E + L ++T +++ P S + + L + Sbjct: 1516 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575 Query: 521 ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577 E+ + S PSSS T P P T + + + S P T + F S T S+ Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635 Query: 578 DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628 + SP P S L+ + S + P S T+ SEKS Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 1695 Query: 629 SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688 S P D +L PA + S + + HS+ +T FP + G + Sbjct: 1696 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 1745 Query: 689 IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748 TA+ S+ PG D +++ +S+ ++T S Sbjct: 1746 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 1783 Query: 749 QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806 S + + PD T +L S V + T S ++T Q Sbjct: 1784 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1831 Query: 807 -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865 + W S + PPTT S +E L G+ P + Sbjct: 1832 FQSWPSSKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 1880 Query: 866 VEMSTSVHSTEMVSVAWPT 884 E ST+VHS+ + + P+ Sbjct: 1881 SEESTTVHSSPVATATTPS 1899 Score = 44.7 bits (104), Expect = 6e-04 Identities = 105/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%) Query: 401 QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460 +SS+ + P S T A+P D + TS + S P ++ + +E+ L + Sbjct: 3024 ESSTSHSQPGS----THTTAFP--DSTTTSGL-----SQEPTASHSSQGSTEATLSPGST 3072 Query: 461 THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520 T SSP E + L ++T +++ P S + + L + Sbjct: 3073 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 3132 Query: 521 ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577 E+ + S PSSS T P P T + + + S P T + F S T S+ Sbjct: 3133 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 3192 Query: 578 DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628 + SP P S L+ + S + P S T+ SEKS Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252 Query: 629 SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688 S P D +L PA + S + + HS+ +T FP + G + Sbjct: 3253 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 3302 Query: 689 IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748 TA+ S+ PG D +++ +S+ ++T S Sbjct: 3303 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSGPG--------- 3340 Query: 749 QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806 S + + PD T +L S V + T S ++T Q Sbjct: 3341 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 3388 Query: 807 -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865 + W + +T PPTT S +E L G+ P + Sbjct: 3389 FQSWPNSKDTTPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 3437 Query: 866 VEMSTSVHSTEMVSVAWPT 884 E ST+VHS+ + + P+ Sbjct: 3438 SEESTTVHSSPVATATTPS 3456 Score = 44.7 bits (104), Expect = 6e-04 Identities = 105/499 (21%), Positives = 171/499 (34%), Gaps = 81/499 (16%) Query: 401 QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460 +SS+ + P S T A+P D + TS + S P ++ + +E+ L + Sbjct: 4107 ESSTSHSQPGS----THTTAFP--DSTTTSGL-----SQEPTTSHSSQGSTEATLSPGST 4155 Query: 461 THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520 T SSP E + L ++T +++ P S + + L + Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTG 4215 Query: 521 ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577 E+ + S PSSS T P P T + + S P T + F S T S+ Sbjct: 4216 LQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 4275 Query: 578 DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628 + SP P S L+ + S + P S T+ SEKS Sbjct: 4276 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 4335 Query: 629 SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688 S P D +L PA + S + + HS+ +T FP + G + Sbjct: 4336 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSMHTTAFPSSTTMPGVSQ- 4385 Query: 689 IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748 TA+ S+ PG D +++ +S+ ++T S Sbjct: 4386 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 4423 Query: 749 QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806 S + + PD T +L S V + T S ++T Q Sbjct: 4424 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 4471 Query: 807 -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865 + W + +T PPTT S +E L G+ P + Sbjct: 4472 FQSWPNSKDTTPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 4520 Query: 866 VEMSTSVHSTEMVSVAWPT 884 E ST+VHS+ + + P+ Sbjct: 4521 SEESTTVHSSPVATATTPS 4539 Score = 43.1 bits (100), Expect = 0.002 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 2559 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 2609 Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + S P D + P S T ES STH FP ++S ++E S+ Sbjct: 2610 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 2665 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 2666 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTTF---QTHPASTHTTPSPPSTA 2711 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 2712 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2756 Score = 42.7 bits (99), Expect = 0.002 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 2085 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 2135 Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + S P D + P S T ES STH FP ++S ++E S+ Sbjct: 2136 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 2191 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 2192 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 2237 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282 Score = 42.7 bits (99), Expect = 0.002 Identities = 171/819 (20%), Positives = 293/819 (35%), Gaps = 120/819 (14%) Query: 367 LLGNSSLNP-DPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPS-- 423 LLG S+ +P S++ + G T + +S++ ++PSS F A+ + Sbjct: 4657 LLGESTTSPISSGSMETTALPG----STTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLG 4712 Query: 424 -ADESITSSIPPLDFSSGPPSA--TGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEV 478 ++ES T P+ ++ P A T L ES ST + FP S E Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE- 4771 Query: 479 LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQ 538 S T HS T + S ++ S LVE+ + S ++ P SS T Sbjct: 4772 ---ESRTSHSSTTHTI-------SSPPSTTSALVEEP-TSYHSSPGSIATTHFPESSTTS 4820 Query: 539 PVPKETIPSMEDSDVS--------LTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 +E+ S D + T+S + S F + ++ L + P S Sbjct: 4821 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISP--GSMETTLASTATTPGLS 4878 Query: 591 MEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLV 650 + +++ S + D P S TSS S EP S L ++ E Sbjct: 4879 AKSTILYS------SSRSPDQTLSPASMTSSSISGEPTS----------LYSQAESTHTT 4922 Query: 651 LVDKMDSTDQISKHSKYEHDD----RSTHFPEEEPLSGPAVPIFADTAAESASL-TLPKH 705 +T +S+ S H +T P S A + ++L T+ Sbjct: 4923 AFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPA 4982 Query: 706 ISEVPGVDDYSVT--KAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEV 763 + VPG+ + S T +P + A S S S I + +S + Sbjct: 4983 STTVPGLSEESTTFYSSPGSTETTAFSHSNTMS-----IHSQQSTPFPDSPGFTHTVLPA 5037 Query: 764 SMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTI 823 ++ D+ T S T + + L P + + S T +T P ++ Sbjct: 5038 TLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTF-YISPSPTYTTLFPASSS 5096 Query: 824 STLLEDEVIMGVQDISLELDRIGTDYYQP------EQVQEQNGKVGSYVEMSTSVHSTEM 877 ++ L +E S + T+ + ++ Q NGK + Sbjct: 5097 TSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGYVGYQCLSP 5156 Query: 878 VSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVP 937 + ++P E + L+ T + +++VT F+E + + +S EY+ F + Sbjct: 5157 LE-SFPVETPEKLNAT-------LGMTVKVTYRNFTEKMNDASSQEYQNFSTLFKNRMDV 5208 Query: 938 YLQS-NLTGFQNLEILNFRNGSIVVNSRM---------------KFANSVPPNVNNAVYM 981 L+ NL ++ + I NGSIVV + + A V + N Sbjct: 5209 VLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYTLEYEELFENLAEIVKAKIMNETRT 5268 Query: 982 IL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEANPCKFQACNEFSECL-VNPWSGEA 1034 L D C A Y+ + +D V G D C +A +++ V+ G+ Sbjct: 5269 TLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQEQCTQKAAEGYTQFYYVDVLDGKL 5325 Query: 1035 KC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHC 1092 C +C G S Q C+L G C + G C C WY G+ C Sbjct: 5326 ACVNKCTKGTKS------QMNCNL--------GTCQLQRS-GPRCLCPNTNTHWYWGETC 5370 Query: 1093 EEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHH 1131 E +++ ++ GI A + LL+ +I F + + H Sbjct: 5371 EFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQRKRH 5409 Score = 41.6 bits (96), Expect = 0.005 Identities = 59/225 (26%), Positives = 91/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 1002 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 1052 Query: 429 T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + SS D + P S T ES + STH FP ++S ++E S+ Sbjct: 1053 SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS---TTSSGIVEAST-R 1108 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 1109 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 1154 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 1199 Score = 38.1 bits (87), Expect = 0.053 Identities = 58/225 (25%), Positives = 89/225 (39%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + S + + Sbjct: 3642 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGSSQESTT 3692 Query: 429 T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + SS D + P S T ES STH FP ++S ++E S+ Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 3748 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 3749 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 3794 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 3795 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839 Score = 37.0 bits (84), Expect = 0.12 Identities = 60/284 (21%), Positives = 92/284 (32%), Gaps = 31/284 (10%) Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526 P SSP + + L ++ T +L+ PV S T H ++ + Sbjct: 362 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSS--TGSPHTTLSPSSSTTHEGEPT 419 Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583 + S PSS T P P T + + SSP T + F S T S+ + S Sbjct: 420 TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS 479 Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637 P P S + + S + +P S T+S S E Sbjct: 480 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE----------- 528 Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEH---DDRSTHFPEEEPLSGPAVPIFADTA 694 A ST H+ Y +THF + +SG + A + Sbjct: 529 ---SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 585 Query: 695 AESASLTLPKHISEVPGVDDYSVTKAPL---ILTSVAISASTDK 735 + A T P V T +P+ + + A+ ST K Sbjct: 586 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK 629 Score = 36.2 bits (82), Expect = 0.20 Identities = 98/434 (22%), Positives = 157/434 (36%), Gaps = 41/434 (9%) Query: 416 TFQAAWPSADESI------TSSIPPLDFSS-GPPSATGRELWSESPLGDLVSTHKLAFPS 468 TFQ+ WPS+ +++ TS+ L +S G PS+T +S S ST Sbjct: 1831 TFQS-WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS------STTLGRSEE 1883 Query: 469 KMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPV-ASEERTSGSHLVEDGLANVEESEDFLS 527 + SSP + S T +++ +S T H E A+ E S Sbjct: 1884 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE---S 1940 Query: 528 IDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLP 587 S S++ T P T ++ + S SSP T++ F S TS ++ S Sbjct: 1941 RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 2000 Query: 588 DASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEP--LSKPWLEDDDSLLPAEIE 645 DA+ L G+ T P S S E +A P + P L + + + Sbjct: 2001 DATGTIVLPARSTTSVLLGEST---TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 2057 Query: 646 DKKLVLVDKMDSTDQISKHSKYEH----DDRSTHFPEEEPLSG-PAVPIFADTAAESASL 700 L ++ +S+ S H +T FP+ G + ++ S Sbjct: 2058 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 2117 Query: 701 TLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFD 760 TL + G S T S S T S + L E T S+ Sbjct: 2118 TLLPASTTTSGPSQESTTS-----HSSPGSTDTALSPGSTTALSFGQESTTFHSSP---G 2169 Query: 761 SEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTP-----QSADRLWLSVTQS 815 S + + PD T I+ S RV + T S +++P +A + + T + Sbjct: 2170 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHT 2229 Query: 816 TKLPPTTISTLLED 829 T PP+T + +E+ Sbjct: 2230 TPSPPSTATAPVEE 2243 Score = 36.2 bits (82), Expect = 0.20 Identities = 52/245 (21%), Positives = 85/245 (34%), Gaps = 20/245 (8%) Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526 P SSP E + L ++ +L+ PV S T H + + Sbjct: 4413 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGEST 4470 Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583 + S P+S T P P T + + + SP T + F S T S+ + S Sbjct: 4471 TFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS 4530 Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637 P P S L+ + S + +P S T+S + E + Sbjct: 4531 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSH-SSTTH 4589 Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAES 697 ++ A LV + S HS +THFP+ SG + A +++ Sbjct: 4590 TISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQD 4641 Query: 698 ASLTL 702 A+ T+ Sbjct: 4642 ATGTI 4646 Score = 35.4 bits (80), Expect = 0.34 Identities = 51/245 (20%), Positives = 85/245 (34%), Gaps = 20/245 (8%) Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526 P S P E + L ++ +L+ PV S T H + + Sbjct: 3330 PESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGEST 3387 Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583 + S P+S T P P T + + + SP T + F S T S+ + S Sbjct: 3388 TFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS 3447 Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637 P P S L+ + S + +P S+T+S + E + Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH-SSTTH 3506 Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAES 697 ++ A LV + S HS +THFP+ SG + A +++ Sbjct: 3507 TISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQD 3558 Query: 698 ASLTL 702 A+ T+ Sbjct: 3559 ATGTI 3563 Score = 35.0 bits (79), Expect = 0.44 Identities = 48/255 (18%), Positives = 99/255 (38%), Gaps = 22/255 (8%) Query: 403 SSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTH 462 SS +T S++++ + S + T+ P +SG + S+ G +V Sbjct: 4592 SSAPSTTSALVEEP-TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 4650 Query: 463 KLAFPSKMGLSSSPEV----LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLAN 518 + +G S++ + +E ++L + TP + + S ++ + Sbjct: 4651 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTT 4710 Query: 519 VEESEDFLSIDSLPSSSFTQPVP-KETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVK 577 + SE+ ++ S P ++ T P P + T + + + SSP T ++ F S S Sbjct: 4711 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 4770 Query: 578 DQLKVS-----------PFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAE 626 ++ + S P A +E+ + GS + +P S T+S +S E Sbjct: 4771 EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS-----IATTHFPESSTTSGRSEE 4825 Query: 627 PLSKPWLEDDDSLLP 641 + D + + P Sbjct: 4826 STASHSSPDTNGITP 4840 Score = 32.7 bits (73), Expect = 2.2 Identities = 67/307 (21%), Positives = 112/307 (36%), Gaps = 51/307 (16%) Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455 +S++ + P S F + P + T SS P D + P S T S L Sbjct: 663 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 716 Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515 G P S P E + L ++ +L+ +PV S R+ + L G Sbjct: 717 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 766 Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575 + + + S PSS T+P P T + + + SP SSIP T+ Sbjct: 767 --STTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 815 Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635 + + S +E+ + GS + +P S+T+S + E + Sbjct: 816 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 864 Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695 ++ A LV + S HS +THFP+ SG + A ++ Sbjct: 865 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSS 916 Query: 696 ESASLTL 702 + A+ T+ Sbjct: 917 QDATGTI 923 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 45.4 bits (106), Expect = 3e-04 Identities = 106/499 (21%), Positives = 172/499 (34%), Gaps = 81/499 (16%) Query: 401 QSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVS 460 +SS+ + P S T A+P +S T+S D S P ++ + +E+ L + Sbjct: 954 ESSTSHSQPGS----THTTAFP---DSTTTS----DLSQEPTTSHSSQGSTEATLSPGST 1002 Query: 461 THKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVE 520 T SSP E + L ++T +++ P S + + L + Sbjct: 1003 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062 Query: 521 ESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVK 577 E+ + S PSSS T P P T + + + S P T + F S T S+ Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122 Query: 578 DQLKVSP------FLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPL 628 + SP P S L+ + S + P S T+ SEKS Sbjct: 1123 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 1182 Query: 629 SKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVP 688 S P D +L PA + S + + HS+ +T FP + G + Sbjct: 1183 SSP-RSPDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ- 1232 Query: 689 IFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDME 748 TA+ S+ PG D +++ +S+ ++T S Sbjct: 1233 --ESTASHSS-----------PGSTDTTLSPGSTTASSLGPESTTFHSSPG--------- 1270 Query: 749 QITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD-- 806 S + + PD T +L S V + T S ++T Q Sbjct: 1271 ------------STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318 Query: 807 -RLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSY 865 + W S + PPTT S +E L G+ P + Sbjct: 1319 FQSWPSSKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSTPTTHFSASSTTLGR 1367 Query: 866 VEMSTSVHSTEMVSVAWPT 884 E ST+VHS+ + + P+ Sbjct: 1368 SEESTTVHSSPVATATTPS 1386 Score = 41.6 bits (96), Expect = 0.005 Identities = 59/225 (26%), Positives = 91/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 489 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 539 Query: 429 T-SSIPPLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + SS D + P S T ES + STH FP ++S ++E S+ Sbjct: 540 SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS---TTSSGIVEAST-R 595 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 596 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 641 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 642 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 686 Score = 40.4 bits (93), Expect = 0.011 Identities = 69/292 (23%), Positives = 112/292 (38%), Gaps = 45/292 (15%) Query: 867 EMSTSVH-STEMVSVAWPTEGGDDLS-YTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEY 924 E ST+ H S S TE + L+ T + +++VT F+E + + +S EY Sbjct: 1573 EESTTFHTSPSFTSTIVSTESLETLAPETPEKLNATLGMTVKVTYRNFTEKMNDASSQEY 1632 Query: 925 KALEQRFLELLVPYLQS-NLTGFQNLEILNFRNGSIVVNSRM---------------KFA 968 + F + L+ NL ++ + I NGSIVV + + A Sbjct: 1633 QNFSTLFKNRMDVVLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYTLEYEELFENLA 1692 Query: 969 NSVPPNVNNAVYMIL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEANPCKFQACNEF 1022 V + N L D C A Y+ + +D V G D C +A + Sbjct: 1693 EIVKAKIMNETRTTLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQEQCTQKAAEGY 1749 Query: 1023 SECL-VNPWSGEAKC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRC 1079 ++ V+ G+ C +C G S Q C+L G C + G C C Sbjct: 1750 TQFYYVDVLDGKLACVNKCTKGTKS------QMNCNL--------GTCQLQRS-GPRCLC 1794 Query: 1080 RVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHH 1131 WY G+ CE +++ ++ GI A + LL+ +I F + + H Sbjct: 1795 PNTNTHWYWGETCEFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQRKRH 1846 Score = 32.7 bits (73), Expect = 2.2 Identities = 67/307 (21%), Positives = 112/307 (36%), Gaps = 51/307 (16%) Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455 +S++ + P S F + P + T SS P D + P S T S L Sbjct: 150 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 203 Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515 G P S P E + L ++ +L+ +PV S R+ + L G Sbjct: 204 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 253 Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575 + + + S PSS T+P P T + + + SP SSIP T+ Sbjct: 254 --STTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 302 Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635 + + S +E+ + GS + +P S+T+S + E + Sbjct: 303 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 351 Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695 ++ A LV + S HS +THFP+ SG + A ++ Sbjct: 352 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSS 403 Query: 696 ESASLTL 702 + A+ T+ Sbjct: 404 QDATGTI 410 Score = 31.6 bits (70), Expect = 4.9 Identities = 46/183 (25%), Positives = 72/183 (39%), Gaps = 18/183 (9%) Query: 416 TFQAAWPSADESI------TSSIPPLDFSS-GPPSATGRELWSESPLGDLVSTHKLAFPS 468 TFQ+ WPS+ +++ TS+ L +S G PS+T +S S ST Sbjct: 1318 TFQS-WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS------STTLGRSEE 1370 Query: 469 KMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPV-ASEERTSGSHLVEDGLANVEESEDFLS 527 + SSP + S T +++ +S T H E A+ E S Sbjct: 1371 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE---S 1427 Query: 528 IDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLP 587 S S++ T P T ++ + S SSP ++ F S TS ++ S P Sbjct: 1428 RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP 1487 Query: 588 DAS 590 D + Sbjct: 1488 DTN 1490 >gi|55770876 notch4 preproprotein [Homo sapiens] Length = 2003 Score = 45.4 bits (106), Expect = 3e-04 Identities = 32/90 (35%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 1009 DEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068 D NPC+ + C + C+ P SG C+C PGY C QP C N G C Sbjct: 929 DHVNPCESRPCQNGATCMAQP-SGYL-CQCAPGYDGQNCSKELDACQSQP--CHNHGTCT 984 Query: 1069 IMPGHGAICRCRVGENWWYRGKHCEEFVSE 1098 PG G C C G + G CE V E Sbjct: 985 PKPG-GFHCACPPG----FVGLRCEGDVDE 1009 Score = 40.0 bits (92), Expect = 0.014 Identities = 31/99 (31%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQ---PDFCLNDGKCDIM 1070 C Q C+ ++C NP +G C C PGY C + P C + G C Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455 Query: 1071 PGHGAICRCRVGENWWYRGKHCE----EFVSEPVIIGIT 1105 PG C C G Y G CE E +S+P G T Sbjct: 456 PG-SFNCLCPPG----YTGSRCEADHNECLSQPCHPGST 489 Score = 33.9 bits (76), Expect = 0.99 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPG----YLSVEERPCQSLCDLQPDFCLNDG 1065 + + C Q C+ + + C+C PG + VE PC S QP C + G Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS----QP--CFHGG 1059 Query: 1066 KCDIMPGH--GAICRCRVG 1082 C+ G G IC C G Sbjct: 1060 TCEATAGSPLGFICHCPKG 1078 Score = 31.6 bits (70), Expect = 4.9 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 9/68 (13%) Query: 1028 NPWSGEAKCRCFPGYLSVEERPCQSLCD--LQPDFCLNDGKCDIMPGHGAICRCRVGENW 1085 +P + C C PG+ ER CQ+ + P FC G+C I C C G Sbjct: 95 SPLTPSFLCTCLPGFTG--ER-CQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG--- 148 Query: 1086 WYRGKHCE 1093 + G+ C+ Sbjct: 149 -WTGEQCQ 155 >gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial [Homo sapiens] Length = 1063 Score = 45.1 bits (105), Expect = 4e-04 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%) Query: 909 NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966 + FS DL + S Y+ + F + +++ GF + +EIL+ RNGSIVV+ + Sbjct: 771 DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 829 Query: 967 FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022 P LE T+ + S D S ++ F+ N Sbjct: 830 LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 881 Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070 S+ + P EA CR FP + R C + C D ++ G+C ++ Sbjct: 882 SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 936 Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119 G CRC + W+ G CE V ++G A L+++ A+ Sbjct: 937 ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 985 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 45.1 bits (105), Expect = 4e-04 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%) Query: 909 NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966 + FS DL + S Y+ + F + +++ GF + +EIL+ RNGSIVV+ + Sbjct: 1194 DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 1252 Query: 967 FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022 P LE T+ + S D S ++ F+ N Sbjct: 1253 LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 1304 Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070 S+ + P EA CR FP + R C + C D ++ G+C ++ Sbjct: 1305 SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 1359 Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119 G CRC + W+ G CE V ++G A L+++ A+ Sbjct: 1360 ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 1408 Score = 33.1 bits (74), Expect = 1.7 Identities = 96/481 (19%), Positives = 166/481 (34%), Gaps = 55/481 (11%) Query: 169 LTYAKETVSSSELSSPV--PVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNE 226 +T T+S S +S P TST+ D+T + + ++E+SL S+ Sbjct: 318 VTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTT 377 Query: 227 IENVIEEATKPAGEQIA---EFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTG 283 E AT P + E S H + + + H I+ E Sbjct: 378 -----ETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHS 432 Query: 284 LPGYKEIRVLEFRSPKENDSGVDVYYAVTFNGEAISNTTWDLIS-LHSNKVENHGLVELD 342 P + F + K + ++ E S++T S + + + +H Sbjct: 433 TPRFTS----SFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFT 488 Query: 343 DKPTVVYTIS-NFRDYIA-----ETLQQNFLLGNSSL-------NPDPDSLQLINVRGVL 389 T T S N R + + ET + SS+ + P I Sbjct: 489 SSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETP 548 Query: 390 RHQTEDLV-W-NTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSS-GPPSATG 446 H T L W T ++ TP T + TSSI + +S PS + Sbjct: 549 LHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSS 608 Query: 447 RELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERT 506 ++S VST A S S + ++T VTP+ L T +P S Sbjct: 609 STIYST------VSTSTTAITSHFTTSET-------AVTPTPVTPSSLSTDIPTTSLRTL 655 Query: 507 SGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIP 566 + S + ++ + DF SI P+ T P I S + TSS T+S Sbjct: 656 TPSSVGTS--TSLTTTTDFPSI---PTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPT 710 Query: 567 FGLDSLTSKVKDQLKVSPF------LPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS 620 +T ++ + +S F +P+ + + G+ + +T+ +++S Sbjct: 711 MSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFGSTDSS 770 Query: 621 S 621 + Sbjct: 771 T 771 >gi|169170721 PREDICTED: similar to intestinal mucin [Homo sapiens] Length = 310 Score = 45.1 bits (105), Expect = 4e-04 Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 32/229 (13%) Query: 909 NMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGF--QNLEILNFRNGSIVVNSRMK 966 + FS DL + S Y+ + F + +++ GF + +EIL+ RNGSIVV+ + Sbjct: 18 DQQFSPDLNDNTSQAYRDFNKTFWNQMQKIF-ADMQGFTFKGVEILSLRNGSIVVDYLVL 76 Query: 967 FANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQA----CNEF 1022 P LE T+ + S D S ++ F+ N Sbjct: 77 LEMPFSPQ--------LESEYEQVKTTLKEGLQNASQDANSCQDSQTLCFKPDSIKVNNN 128 Query: 1023 SECLVNPWSGEAKCR----------CFPGYLSVEERPCQSLCDLQPDFCLN--DGKCDIM 1070 S+ + P EA CR FP + R C + C D ++ G+C ++ Sbjct: 129 SKTELTP---EAICRRAAPTGYEEFYFPLVEATRLR-CVTKCTSGVDNAIDCHQGQC-VL 183 Query: 1071 PGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAI 1119 G CRC + W+ G CE V ++G A L+++ A+ Sbjct: 184 ETSGPACRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLAL 232 >gi|24430141 fibrillin 1 precursor [Homo sapiens] Length = 2871 Score = 44.7 bits (104), Expect = 6e-04 Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 27/120 (22%) Query: 984 EDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNP----------WSGE 1033 E FCT + + Y + G P + ++C + EC NP GE Sbjct: 1209 ETFCTNSEGS-------YECSCQPGFALMPDQ-RSCTDIDECEDNPNICDGGQCTNIPGE 1260 Query: 1034 AKCRCFPGYLSVEE-RPCQSL--CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGK 1090 +C C+ G+++ E+ + C + CDL P+ CL+ G C+ G IC C +G Y GK Sbjct: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKG-SFICHCDMG----YSGK 1314 >gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] Length = 236 Score = 44.7 bits (104), Expect = 6e-04 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 7/101 (6%) Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMP 1071 +PC+ C C+ G+A CRC G+ + + S CLN G C ++ Sbjct: 27 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLS 86 Query: 1072 GHGAICRCRVGENWWYRGKHC---EEFVSEPVIIGITIASV 1109 C C+VG + GK C + +S P G T +V Sbjct: 87 RDTYECTCQVG----FTGKECQWTDACLSHPCANGSTCTTV 123 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 43.9 bits (102), Expect = 0.001 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 5/87 (5%) Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073 C CNE S C NP +G+A C C GY C L + C + GKC G Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLG- 434 Query: 1074 GAICRCRVGENWWYRGKHCEEFVSEPV 1100 C+C G Y G CE V+E V Sbjct: 435 SFECQCLQG----YTGPRCEIDVNECV 457 Score = 35.8 bits (81), Expect = 0.26 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 1006 ESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDG 1065 +S +A+PC C +CL P+ C C P + R + C +P C + G Sbjct: 136 KSCQQADPCASNPCANGGQCL--PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGG 193 Query: 1066 KCDIMPG-HGAICRCRVGENWWYRGKHCE 1093 C G + +CR + G +CE Sbjct: 194 TCHNEVGSYRCVCRAT------HTGPNCE 216 Score = 35.4 bits (80), Expect = 0.34 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 13/90 (14%) Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRC-----FPGYLSVEERPCQSLCDLQPDFCLND 1064 + NPC C C V G A C F G L + P + C P C N Sbjct: 59 DPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT--PLDNACLTNP--CRNG 114 Query: 1065 GKCDIMPGHGAICRCRVGENWWYRGKHCEE 1094 G CD++ CRC G + GK C++ Sbjct: 115 GTCDLLTLTEYKCRCPPG----WSGKSCQQ 140 Score = 34.7 bits (78), Expect = 0.58 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 1010 EANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDI 1069 + N C C + CL GE +C C PGY V C P CL++G+C + Sbjct: 452 DVNECVSNPCQNDATCLDQ--IGEFQCICMPGYEGVHCEVNTDECASSP--CLHNGRC-L 506 Query: 1070 MPGHGAICRCRVGENWWYRGKHCEEFVSE 1098 + C C G + G C+ V E Sbjct: 507 DKINEFQCECPTG----FTGHLCQYDVDE 531 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 43.1 bits (100), Expect = 0.002 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073 C+ Q C C + C C PG V+ R C+ L P+ C + G+C+ PG Sbjct: 738 CESQPCRAGGTCSSDGMGFH--CTCPPG---VQGRQCELLSPCTPNPCEHGGRCESAPGQ 792 Query: 1074 GAICRCRVGENWWYRGKHCEEFVSE 1098 +C C G ++G C++ V E Sbjct: 793 LPVCSCPQG----WQGPRCQQDVDE 813 Score = 40.4 bits (93), Expect = 0.011 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 1014 CKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGH 1073 C C+E + C NP +G A C C PG+ C + + C + G+C G Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQG- 413 Query: 1074 GAICRCRVGENWWYRGKHCEEFVSE 1098 +C+C G Y G CE V+E Sbjct: 414 SFLCQCGRG----YTGPRCETDVNE 434 Score = 36.2 bits (82), Expect = 0.20 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 15/85 (17%) Query: 1017 QACNEFSECLVNPWS--------GEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068 + + ECL NP C C PGY Q L D P C N G C Sbjct: 883 RCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCE--QDLPDCSPSSCFNGGTC- 939 Query: 1069 IMPGHGAICRCRVGENWWYRGKHCE 1093 + + C CR G Y G HC+ Sbjct: 940 VDGVNSFSCLCRPG----YTGAHCQ 960 Score = 30.8 bits (68), Expect = 8.4 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 7/64 (10%) Query: 1036 CRCFPGYLSVEERPCQSLCDLQPDFCLNDGKC-DIMPGHGAICRCRVGENWWYRGKHCEE 1094 C+C P + C LQP+ C N G C + + GH +C N W G+ C + Sbjct: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC-----VNGW-TGESCSQ 313 Query: 1095 FVSE 1098 + + Sbjct: 314 NIDD 317 >gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] Length = 587 Score = 42.7 bits (99), Expect = 0.002 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 161 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 211 Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + S P D + P S T ES STH FP ++S ++E S+ Sbjct: 212 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 267 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 268 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 313 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 314 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 358 >gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens] Length = 456 Score = 42.7 bits (99), Expect = 0.002 Identities = 59/225 (26%), Positives = 90/225 (40%), Gaps = 30/225 (13%) Query: 369 GNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESI 428 G++ PDS G+ RH T T SS +T +++L + + PS + + Sbjct: 55 GSTHTTAFPDST---TTPGLSRHST------TSHSSPGSTDTTLLPASTTTSGPSQESTT 105 Query: 429 TSSIP-PLDFSSGPPSATGRELWSESPL--GDLVSTHKLAFPSKMGLSSSPEVLEVSSLT 485 + S P D + P S T ES STH FP ++S ++E S+ Sbjct: 106 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---TTSSGIVEAST-R 161 Query: 486 LHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETI 545 +HS T + T P +S GL ES F + P+S+ T P P T Sbjct: 162 VHSSTGSPRTTLSPASS---------TSPGLQG--ESTAF---QTHPASTHTTPSPPSTA 207 Query: 546 PSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDAS 590 + + + SP T + F S TS ++ + PDAS Sbjct: 208 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 252 >gi|194328809 latent transforming growth factor beta binding protein 3 isoform 1 [Homo sapiens] Length = 1303 Score = 42.4 bits (98), Expect = 0.003 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 1001 YSLDVESGDEA----NPC-KFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERP--CQSL 1053 Y L V +G + N C K C + C+ P G KC C+PGY RP C+ + Sbjct: 647 YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP--GHYKCNCYPGYRLKASRPPVCEDI 704 Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVG 1082 + + DGKC+ PG C+ G Sbjct: 705 DECRDPSSCPDGKCENKPGSFKCIACQPG 733 Score = 38.5 bits (88), Expect = 0.040 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 1002 SLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSL--CDLQPD 1059 S D ++ + C F A +C+ +G +C C G+ V R CQ + C P Sbjct: 818 SRDRSHCEDIDECDFPAACIGGDCINT--NGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875 Query: 1060 FCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEP 1099 CL G C + G +C C G CEE V +P Sbjct: 876 LCLPHGACKNLQG-SYVCVCDEGFTPTQDQHGCEE-VEQP 913 >gi|18497288 latent transforming growth factor beta binding protein 3 isoform 2 [Homo sapiens] Length = 1256 Score = 42.4 bits (98), Expect = 0.003 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 1001 YSLDVESGDEA----NPC-KFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERP--CQSL 1053 Y L V +G + N C K C + C+ P G KC C+PGY RP C+ + Sbjct: 647 YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP--GHYKCNCYPGYRLKASRPPVCEDI 704 Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVG 1082 + + DGKC+ PG C+ G Sbjct: 705 DECRDPSSCPDGKCENKPGSFKCIACQPG 733 Score = 38.5 bits (88), Expect = 0.040 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 1002 SLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSL--CDLQPD 1059 S D ++ + C F A +C+ +G +C C G+ V R CQ + C P Sbjct: 818 SRDRSHCEDIDECDFPAACIGGDCINT--NGSYRCLCPQGHRLVGGRKCQDIDECSQDPS 875 Query: 1060 FCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEP 1099 CL G C + G +C C G CEE V +P Sbjct: 876 LCLPHGACKNLQG-SYVCVCDEGFTPTQDQHGCEE-VEQP 913 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 42.4 bits (98), Expect = 0.003 Identities = 164/783 (20%), Positives = 278/783 (35%), Gaps = 115/783 (14%) Query: 402 SSSLQATPSSILDNTFQAA---WPSADESITSSIPPLDFSSGPPSA--TGRELWSESPL- 455 S++ +PSSI F A+ + ++ES T P+ ++ P A T L ES Sbjct: 1163 STTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAY 1222 Query: 456 -GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVED 514 ST + FP S E S T HS T + S ++ S LVE+ Sbjct: 1223 HSSPGSTQTMHFPESSTASGRSE----ESRTSHSSTTHTI-------SSPPSTTSALVEE 1271 Query: 515 GLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVS--------LTSSPYLTSSIP 566 + S ++ P SS T +E+ S D + T+S + S Sbjct: 1272 P-TSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTT 1330 Query: 567 FGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAE 626 F + ++ L + P S + +++ S + D P S TSS S E Sbjct: 1331 FYISP--GSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGE 1382 Query: 627 PLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDD----RSTHFPEEEPL 682 P S L ++ E +T +S+ S H +T P Sbjct: 1383 PTS----------LYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITT 1432 Query: 683 SGPAVPIFADTAAESASL-TLPKHISEVPGVDDYSVT--KAPLILTSVAISASTDKSDQA 739 S A + ++L T+ + VPG+ + S T +P + A S S S Sbjct: 1433 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS--- 1489 Query: 740 DAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILA 799 I + +S + ++ D+ T S T + + L Sbjct: 1490 --IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLV 1547 Query: 800 STPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQP------E 853 P + + S T +T P ++ ++ L +E S + T+ + + Sbjct: 1548 GEPTTF-YISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQ 1606 Query: 854 QVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFS 913 + Q NGK + + ++P E + L+ T + +++VT F+ Sbjct: 1607 EGQIWNGKQCVCPQGYVGYQCLSPLE-SFPVETPEKLNAT-------LGMTVKVTYRNFT 1658 Query: 914 EDLFNKNSLEYKALEQRFLELLVPYLQS-NLTGFQNLEILNFRNGSIVVNSRM------- 965 E + + +S EY+ F + L+ NL ++ + I NGSIVV + + Sbjct: 1659 EKMNDASSQEYQNFSTLFKNRMDVVLKGDNLPQYRGVNIRRLLNGSIVVKNDVILEADYT 1718 Query: 966 --------KFANSVPPNVNNAVYMIL--EDFCTTA---YNTMNLAIDKYSLDVESG-DEA 1011 A V + N L D C A Y+ + +D V G D Sbjct: 1719 LEYEELFENLAEIVKAKIMNETRTTLLDPDSCRKAILCYSEEDTFVDS---SVTPGFDFQ 1775 Query: 1012 NPCKFQACNEFSECL-VNPWSGEAKC--RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCD 1068 C +A +++ V+ G+ C +C G S Q C+L G C Sbjct: 1776 EQCTQKAAEGYTQFYYVDVLDGKLACVNKCTKGTKS------QMNCNL--------GTCQ 1821 Query: 1069 IMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQ 1128 + G C C WY G+ CE +++ ++ GI A + LL+ +I F + + Sbjct: 1822 LQRS-GPRCLCPNTNTHWYWGETCEFNIAKSLVYGIVGAVMAVLLLALIILIILFSLSQR 1880 Query: 1129 AHH 1131 H Sbjct: 1881 KRH 1883 Score = 37.4 bits (85), Expect = 0.090 Identities = 60/284 (21%), Positives = 92/284 (32%), Gaps = 31/284 (10%) Query: 467 PSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFL 526 P SSP + + L ++ T +L+ PV S T H ++ + Sbjct: 283 PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSS--TGSPHTTLSPASSTTHEGEPT 340 Query: 527 SIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLT---SKVKDQLKVS 583 + S PSS T P P T + + SSP T + F S T S+ + S Sbjct: 341 TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS 400 Query: 584 PFL------PDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDD 637 P P S + + S + +P S T+S S E Sbjct: 401 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE----------- 449 Query: 638 SLLPAEIEDKKLVLVDKMDSTDQISKHSKYEH---DDRSTHFPEEEPLSGPAVPIFADTA 694 A ST H+ Y +THF + +SG + A + Sbjct: 450 ---SATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHS 506 Query: 695 AESASLTLPKHISEVPGVDDYSVTKAPL---ILTSVAISASTDK 735 + A T P V T +P+ + + A+ ST K Sbjct: 507 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK 550 Score = 33.9 bits (76), Expect = 0.99 Identities = 67/307 (21%), Positives = 113/307 (36%), Gaps = 51/307 (16%) Query: 401 QSSSLQATPSSILDNTFQAA--WPSADESIT---SSIPPLDFSSGPPSATGRELWSESPL 455 +S++ + P S F + P + T SS P D + P S T S L Sbjct: 584 ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA------SSL 637 Query: 456 GDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDG 515 G P S P E + L ++ +L+ +PV S R+ + L G Sbjct: 638 G----------PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 687 Query: 516 LANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSK 575 + + + S PSS+ T+P P T + + + SP SSIP T+ Sbjct: 688 --STTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSP---SSIP------TTH 736 Query: 576 VKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLED 635 + + S +E+ + GS + +P S+T+S + E + Sbjct: 737 ISARSTTS-----GLVEESTTYHSSPGS-----TQTMHFPESDTTSGRGEESTTS-HSST 785 Query: 636 DDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAA 695 ++ A LV + S HS +THFP+ SG + A ++ Sbjct: 786 THTISSAPSTTSALV-------EEPTSYHSS-PGSTATTHFPDSSTTSGRSEESIASHSS 837 Query: 696 ESASLTL 702 + A+ T+ Sbjct: 838 QDATGTI 844 Score = 31.6 bits (70), Expect = 4.9 Identities = 100/493 (20%), Positives = 170/493 (34%), Gaps = 87/493 (17%) Query: 403 SSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTH 462 SS +T S++++ + S + T+ P +SG + S+ G +V Sbjct: 790 SSAPSTTSALVEEP-TSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPA 848 Query: 463 KLAFPSKMGLSSSPEV----LEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLAN 518 + +G S++ + +E ++L + TP + + S R+ + L + Sbjct: 849 RSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 908 Query: 519 VEESEDFLSIDSLPSSSFTQPVP-KETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVK 577 SE+ + S P S+ T P T P + + SSP T + S T+ + Sbjct: 909 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA-STTTXLV 967 Query: 578 DQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETS---SEKSAEPLSKPWLE 634 + SP + SGS + L P S T+ SEKS S P Sbjct: 968 GEPTTSP----------------ISSGSTETTAL---PGSTTTAGLSEKSTTFYSSP-RS 1007 Query: 635 DDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTA 694 D +L PA + S + + HS+ +T FP + G + TA Sbjct: 1008 PDTTLSPASTTSSGV-------SEESTTSHSR-PGSTHTTAFPGSTTMPGVSQ---ESTA 1056 Query: 695 AESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESS 754 + S+ PG D +++ +S+ ++T S Sbjct: 1057 SHSS-----------PGSTDTTLSPRSTTASSLGPESTTFHSGPG--------------- 1090 Query: 755 NYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSAD---RLWLS 811 S + + PD T +L S V + T S ++T Q + W S Sbjct: 1091 ------STETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPS 1144 Query: 812 VTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSYVEMSTS 871 + PPTT S +E L G+ P + E ST+ Sbjct: 1145 SKDTMPAPPTTTSAFVE-----------LSTTSHGSPSSIPTTHFSASSTTFGRSEESTT 1193 Query: 872 VHSTEMVSVAWPT 884 VHS+ + P+ Sbjct: 1194 VHSSPVAPATTPS 1206 >gi|58530876 melanoma antigen family C, 1 [Homo sapiens] Length = 1142 Score = 42.0 bits (97), Expect = 0.004 Identities = 164/765 (21%), Positives = 261/765 (34%), Gaps = 122/765 (15%) Query: 174 ETVSSSELSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERP-EESISNEIENVIE 232 E S L PV +STL S P +EG +S L+ P S S+ + ++ + Sbjct: 156 EGFPQSVLQIPVSAASSSTLVSIFQSSPESTQSPFEGFPQSPLQIPVSRSFSSTLLSIFQ 215 Query: 233 ---EATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGL----- 284 E T+ E A+ + + + SSS L + F ++ F G Sbjct: 216 SSPERTQSTFEGFAQSPLQI-------PVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSL 268 Query: 285 -----PGYKEIRVLEFR-SPKENDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVE-NHG 337 P + V F+ SP+ S + + S+++ L+SL + E H Sbjct: 269 QIPVSPSFSSTLVSLFQSSPERTQSTFEGFPQSPLQIPVSSSSSSTLLSLFQSSPERTHS 328 Query: 338 LVE-LDDKPTVVYTISNFRDYIAETLQQNFLLGNSSLNPDPDS-LQ----------LINV 385 E + S+F + Q + S+ P S LQ L+++ Sbjct: 329 TFEGFPQSLLQIPMTSSFSSTLLSIFQSSPESAQSTFEGFPQSPLQIPGSPSFSSTLLSL 388 Query: 386 RGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSAT 445 +T S LQ +S +T + S+ ES S+ F P Sbjct: 389 FQSSPERTHSTFEGFPQSPLQIPMTSSFSSTLLSILQSSPESAQSAFE--GFPQSPLQIP 446 Query: 446 GRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSS-------LTLHSVTPAVLQT-- 496 +S + L S+ + + G SP + VSS L+L +P Q+ Sbjct: 447 VSSSFSYTLLSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQSTF 506 Query: 497 -GLPVA------SEERTSGSHLVEDGLANVEESEDFLSIDSLPSS------SFTQPVPKE 543 G P + S +H + ++ E ED LS P S S + + Sbjct: 507 EGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHYFPQ 566 Query: 544 TIPSMEDSDVSLTSSPYLTSSIPFGLDSLT------SKVKDQLKVSP-FLPDASMEKELI 596 + P EDS SP+ P G DSL+ S + + +SP + P + ++ E Sbjct: 567 SPPQGEDS-----LSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGE-E 620 Query: 597 FDGGLGS------------------------GSGQKVDLITWPWSETSSEKSAEPLSKPW 632 F L S G + P S S PL P Sbjct: 621 FQSSLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPE 680 Query: 633 L--EDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPE-----EEPLSGP 685 E +DSL P +I L D + S ++E HFP+ E+ S Sbjct: 681 SAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSL 740 Query: 686 AVPIFADTAAESASLTLPKHISEVPGVDDYSVTKAPL-----ILTSVAISASTDKSDQAD 740 P+ + S SL+LP+ E P ++PL S +++ S ++ Sbjct: 741 QSPV--SICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESP 798 Query: 741 AILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILAS 800 E Q S F S S +L P S + +SSL K S + Sbjct: 799 QSPPEGPAQSPLQSPVSSFPSSTS------SSLSQSSPVSSFPSSTSSSLSKSSPESPLQ 852 Query: 801 TPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRI 845 +P +S + ST L P + + + D LE D + Sbjct: 853 SPV------ISFSSSTSLSPFSEESSSPVDEYTSSSDTLLESDSL 891 >gi|153070262 meprin A alpha [Homo sapiens] Length = 746 Score = 40.8 bits (94), Expect = 0.008 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Query: 1054 CDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLL 1113 CD P C NDG C + G A CRC G ++Y G+ C+ ++G+ I G++ Sbjct: 674 CDPNP--CQNDGICVNVKGM-ASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVI 730 Query: 1114 VIFSAII 1120 + +II Sbjct: 731 FLTFSII 737 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 40.8 bits (94), Expect = 0.008 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 13/79 (16%) Query: 1017 QACNEFSECLVNPWSGEAKC-RCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGA 1075 + C+E CL P C RC PGY CQ+ C P G D + G G Sbjct: 597 EGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPN--CQA-CTCDPR-----GALDQLCGAGG 648 Query: 1076 ICRCRVGENWWYRGKHCEE 1094 +CRCR G Y G C+E Sbjct: 649 LCRCRPG----YTGTACQE 663 >gi|7019499 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha [Homo sapiens] Length = 798 Score = 40.4 bits (93), Expect = 0.011 Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 1133 RSERESPFSGS-SRQPDSLSSIENAVKYNPVYESHRAGCE-------KYEGPYPQHPFYS 1184 RS SP+S S SR P S SS + Y + HR + PY + P Y Sbjct: 576 RSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYD 635 Query: 1185 SASGDVIGGLSREEIRQMYESSELSREEIQERMR 1218 S L REE R+ YE E R + +ER R Sbjct: 636 SYEEYQHERLKREEYRREYEKRESERAKQRERQR 669 >gi|122937283 6720455I24Rik homolog [Homo sapiens] Length = 1413 Score = 40.0 bits (92), Expect = 0.014 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 14/82 (17%) Query: 1012 NPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQ-SLCDLQPDFCLNDGKC-DI 1069 +PC + C +C V +G A C C GY C+ + D PD CLN G C D+ Sbjct: 351 SPCDTKECQHGGQCQVE--NGSAVCVCQAGYTGAA---CEMDVDDCSPDPCLNGGSCVDL 405 Query: 1070 MPGHGAIC-------RCRVGEN 1084 + + +C RC G++ Sbjct: 406 VGNYTCLCAEPFKGLRCETGDH 427 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,012,059 Number of Sequences: 37866 Number of extensions: 2269230 Number of successful extensions: 6046 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 117 Number of HSP's that attempted gapping in prelim test: 5728 Number of HSP's gapped (non-prelim): 426 length of query: 1241 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1127 effective length of database: 13,930,794 effective search space: 15700004838 effective search space used: 15700004838 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.