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Search of human proteins with 56549137
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549137 transgelin 3 [Homo sapiens]
(199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549135 transgelin 3 [Homo sapiens] 410 e-115
gi|56549139 transgelin 3 [Homo sapiens] 410 e-115
gi|56549137 transgelin 3 [Homo sapiens] 410 e-115
gi|4507357 transgelin 2 [Homo sapiens] 301 3e-82
gi|48255907 transgelin [Homo sapiens] 282 2e-76
gi|48255905 transgelin [Homo sapiens] 282 2e-76
gi|4502923 calponin 3 [Homo sapiens] 145 2e-35
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 142 1e-34
gi|4758018 calponin 2 isoform a [Homo sapiens] 134 4e-32
gi|41327730 calponin 2 isoform b [Homo sapiens] 114 7e-26
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 42 4e-04
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 41 6e-04
gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 41 6e-04
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 41 8e-04
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 39 0.004
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 38 0.005
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 38 0.005
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 36 0.025
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 34 0.094
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 34 0.094
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 34 0.094
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 32 0.27
gi|223718250 plastin 1 [Homo sapiens] 32 0.27
gi|223718246 plastin 1 [Homo sapiens] 32 0.27
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 31 0.61
gi|167614506 L-plastin [Homo sapiens] 30 1.4
gi|209862851 plastin 3 [Homo sapiens] 30 1.8
gi|7549809 plastin 3 [Homo sapiens] 30 1.8
gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo ... 27 8.8
gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo ... 27 8.8
>gi|56549135 transgelin 3 [Homo sapiens]
Length = 199
Score = 410 bits (1053), Expect = e-115
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
Query: 181 NKGASQAGMTGYGMPRQIM 199
NKGASQAGMTGYGMPRQIM
Sbjct: 181 NKGASQAGMTGYGMPRQIM 199
>gi|56549139 transgelin 3 [Homo sapiens]
Length = 199
Score = 410 bits (1053), Expect = e-115
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
Query: 181 NKGASQAGMTGYGMPRQIM 199
NKGASQAGMTGYGMPRQIM
Sbjct: 181 NKGASQAGMTGYGMPRQIM 199
>gi|56549137 transgelin 3 [Homo sapiens]
Length = 199
Score = 410 bits (1053), Expect = e-115
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
Query: 181 NKGASQAGMTGYGMPRQIM 199
NKGASQAGMTGYGMPRQIM
Sbjct: 181 NKGASQAGMTGYGMPRQIM 199
>gi|4507357 transgelin 2 [Homo sapiens]
Length = 199
Score = 301 bits (770), Expect = 3e-82
Identities = 139/199 (69%), Positives = 169/199 (84%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MANRGP+YGLSREVQ+KIE++YDADLE L+ WI QC +D+ P PGR +FQ WL DGT
Sbjct: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60
Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
VLC+LIN+LYP GQ P+ KI S MAFKQMEQISQFL+AAE YG+ TTDIFQTVDLWEGK
Sbjct: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120
Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180
+MA VQRTLM LG +AV +DDG + G+P+WF +K+++N R FS+ QL++G+NVIGLQMG+
Sbjct: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180
Query: 181 NKGASQAGMTGYGMPRQIM 199
N+GASQAGMTGYGMPRQI+
Sbjct: 181 NRGASQAGMTGYGMPRQIL 199
>gi|48255907 transgelin [Homo sapiens]
Length = 201
Score = 282 bits (721), Expect = 2e-76
Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G
Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
Query: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118
+L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E
Sbjct: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119
Query: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178
GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM
Sbjct: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179
Query: 179 GSNKGASQAGMTGYGMPRQIM 199
GSN+GASQAGMTGYG PRQI+
Sbjct: 180 GSNRGASQAGMTGYGRPRQII 200
>gi|48255905 transgelin [Homo sapiens]
Length = 201
Score = 282 bits (721), Expect = 2e-76
Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%)
Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G
Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
Query: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118
+L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E
Sbjct: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119
Query: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178
GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM
Sbjct: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179
Query: 179 GSNKGASQAGMTGYGMPRQIM 199
GSN+GASQAGMTGYG PRQI+
Sbjct: 180 GSNRGASQAGMTGYGRPRQII 200
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 145 bits (367), Expect = 2e-35
Identities = 88/203 (43%), Positives = 119/203 (58%), Gaps = 26/203 (12%)
Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
N+GPSYGLS EV+ KI KYD E L +WI E++ G +FQ L DG +L
Sbjct: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWI-----EEVTGMSIG-PNFQLGLKDGIIL 58
Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
C+LIN L P + K++ES + + Q+E I F+KA + YG++ DIF+ DL+E +M
Sbjct: 59 CELINKLQPGS---VKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115
Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFH-------RKAQQNRRGFSEEQLRQGQNVIG 175
VQ TL+AL +A TK FH + A++ R F E +L+ GQ+VIG
Sbjct: 116 TQVQTTLVALAGLAKTKG----------FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIG 165
Query: 176 LQMGSNKGASQAGMTGYGMPRQI 198
LQMG+NK ASQAGMT YG R +
Sbjct: 166 LQMGTNKCASQAGMTAYGTRRHL 188
Score = 35.8 bits (81), Expect = 0.025
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 172 NVIGLQMGSNKGASQAGMTGYGMPRQI 198
+ I LQMG+NK ASQ GM+ YG+ RQ+
Sbjct: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 142 bits (359), Expect = 1e-34
Identities = 85/196 (43%), Positives = 115/196 (58%), Gaps = 14/196 (7%)
Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
NRGP+YGLS EV+ K+ QKYD E +L +WI E + G +F L DG +L
Sbjct: 7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWI-----EGVTGRRIGN-NFMDGLKDGIIL 60
Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
C+ IN L P + KI+ES + Q+E I F+KA YGV+ DIF+ DL+E +
Sbjct: 61 CEFINKLQPGS---VKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNH 117
Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
VQ TL+AL S+A TK + G + A++ R F +LR+G+N+IGLQMG+NK
Sbjct: 118 TQVQSTLLALASMAKTKGNKVNVGV-----KYAEKQERKFEPGKLREGRNIIGLQMGTNK 172
Query: 183 GASQAGMTGYGMPRQI 198
ASQ GMT YG R +
Sbjct: 173 FASQQGMTAYGTRRHL 188
Score = 44.7 bits (104), Expect = 5e-05
Identities = 19/25 (76%), Positives = 22/25 (88%)
Query: 174 IGLQMGSNKGASQAGMTGYGMPRQI 198
+ LQMGSNKGASQ GMT YG+PRQ+
Sbjct: 243 VSLQMGSNKGASQRGMTVYGLPRQV 267
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 134 bits (338), Expect = 4e-32
Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 12/196 (6%)
Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L
Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60
Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M
Sbjct: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
VQ +L+AL A TK G G + +++ R F + ++ GQ VIGLQMG+NK
Sbjct: 118 TQVQVSLLALAGKAKTK--GLQSGVDIGV-KYSEKQERNFDDATMKAGQCVIGLQMGTNK 174
Query: 183 GASQAGMTGYGMPRQI 198
ASQ+GMT YG R +
Sbjct: 175 CASQSGMTAYGTRRHL 190
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 114 bits (284), Expect = 7e-26
Identities = 74/196 (37%), Positives = 104/196 (53%), Gaps = 11/196 (5%)
Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L
Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60
Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M
Sbjct: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
VQ +L+AL T G ++ R+ + + + + I LQMG+NK
Sbjct: 118 TQVQVSLLALAGKMGTNKCASQSGMTAYGTRRHLYDPKNHILPPM--DHSTISLQMGTNK 175
Query: 183 GASQAGMTGYGMPRQI 198
ASQ GMT G R I
Sbjct: 176 CASQVGMTAPGTRRHI 191
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 41.6 bits (96), Expect = 4e-04
Identities = 33/109 (30%), Positives = 49/109 (44%), Gaps = 14/109 (12%)
Query: 52 FQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIF 111
F+ L +G +LC LIN L P I KI+ ++ I+ FLKA E G++ +F
Sbjct: 87 FRASLENGVLLCDLINKLKP---GVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLF 143
Query: 112 QTVDLWEGKDMAAV--QRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQN 158
DL + + V + T + +V +T W RKAQ N
Sbjct: 144 HPGDLQDLSNRVTVKQEETDRRVKNVLITL---------YWLGRKAQSN 183
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 41.2 bits (95), Expect = 6e-04
Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 56 LMDGTVLCKLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLK-AAETYGVRTTDIFQT 113
L DG +LC+L+N+L P +M+ F ++ I FL E +G++ +++F+
Sbjct: 37 LRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEA 96
Query: 114 VDLWEGKDMAAVQRTLMALGSVAVTKDDG 142
DL++ +D V TL AL + ++ G
Sbjct: 97 FDLFDVQDFGKVIYTLSALSWTPIAQNRG 125
>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
containing 1 [Homo sapiens]
Length = 728
Score = 41.2 bits (95), Expect = 6e-04
Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 18/138 (13%)
Query: 6 PSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKL 65
P + + R++++ E+K +L +L + I ++ + H G A LMDG VLC L
Sbjct: 565 PQFTIRRKMEQMREEK---ELVEQLRESIEMRLKVSL-HEDLGAA-----LMDGVVLCHL 615
Query: 66 INSLYPPG----QEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKD 121
+N + P P P + + MA K + FL+A GV D+ D+ + D
Sbjct: 616 VNHIRPRSVASIHVPSPAVPKLSMA-KCRRNVENFLEACRKLGVPEADLCSPCDILQ-LD 673
Query: 122 MAAVQR---TLMALGSVA 136
+++ TL+ALG A
Sbjct: 674 FRHIRKTVDTLLALGEKA 691
>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 847
Score = 40.8 bits (94), Expect = 8e-04
Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 10/93 (10%)
Query: 56 LMDGTVLCKLINSL--YPPGQEPI---PKISESKMAFKQMEQISQFLKAA-ETYGVRTTD 109
L DG +LC+L+N+L + + I P++S+ F ++ I FL A ET+G+R ++
Sbjct: 37 LRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ----FLCLKNIRTFLTACCETFGMRKSE 92
Query: 110 IFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDG 142
+F+ DL++ +D V TL L + G
Sbjct: 93 LFEAFDLFDVRDFGKVIETLSRLSRTPIALATG 125
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 38.5 bits (88), Expect = 0.004
Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Query: 27 ENKLVDWII-LQCAEDIEHPPPGRAHFQKW-LMDGTVLCKLINSLYPPGQEPIPKISESK 84
E ++V W+I L E + F K L +G VLCKLIN L P E + +
Sbjct: 4 EEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKF--CLDPQ 61
Query: 85 MAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMAL 132
+ I+ FLK T V +IF DL+ G + + V TL+A+
Sbjct: 62 TEADCINNINDFLKGCATLQV---EIFDPDDLYSGVNFSKVLSTLLAV 106
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 38.1 bits (87), Expect = 0.005
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 10/91 (10%)
Query: 56 LMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAA-ETYGVRTTDIFQ 112
L DG +LC+L+++L PG + I+ F ++ I FLK + +G+R +++F
Sbjct: 37 LRDGVLLCQLLHNL-SPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95
Query: 113 TVDLWE----GKDMAAVQRTLMALGSVAVTK 139
DL++ GK ++AV R ++L S+A K
Sbjct: 96 PFDLFDVRDFGKVISAVSR--LSLHSIAQNK 124
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 38.1 bits (87), Expect = 0.005
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 10/91 (10%)
Query: 56 LMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAA-ETYGVRTTDIFQ 112
L DG +LC+L+++L PG + I+ F ++ I FLK + +G+R +++F
Sbjct: 37 LRDGVLLCQLLHNL-SPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95
Query: 113 TVDLWE----GKDMAAVQRTLMALGSVAVTK 139
DL++ GK ++AV R ++L S+A K
Sbjct: 96 PFDLFDVRDFGKVISAVSR--LSLHSIAQNK 124
>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
containing 2 [Homo sapiens]
Length = 765
Score = 35.8 bits (81), Expect = 0.025
Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 20/132 (15%)
Query: 12 REVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYP 71
RE +E+I Q L N L + + +DI G A LMDG VLC L N + P
Sbjct: 643 REEREQIRQ-----LRNNLESRLKVILPDDI-----GAA-----LMDGVVLCHLANHIRP 687
Query: 72 PG----QEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQR 127
P P + + MA K + FL A + GV + + E + + V
Sbjct: 688 RSVASIHVPSPAVPKLSMA-KCRRNVENFLDACKKLGVSQERLCLPHHILEERGLVKVGV 746
Query: 128 TLMALGSVAVTK 139
T+ AL + TK
Sbjct: 747 TVQALLELPTTK 758
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 33.9 bits (76), Expect = 0.094
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107
G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++
Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96
Query: 108 TDIFQTVDLWEGKDMAAVQ 126
+ +F DL + + V+
Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 33.9 bits (76), Expect = 0.094
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107
G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++
Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96
Query: 108 TDIFQTVDLWEGKDMAAVQ 126
+ +F DL + + V+
Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 33.9 bits (76), Expect = 0.094
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107
G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++
Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96
Query: 108 TDIFQTVDLWEGKDMAAVQ 126
+ +F DL + + V+
Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 32.3 bits (72), Expect = 0.27
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 10/109 (9%)
Query: 31 VDWII----LQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMA 86
V W+I L+ + P G Q L DG VLC+L+ L P E + E +
Sbjct: 8 VTWLITLGVLESPKKTISDPEG--FLQASLKDGVVLCRLLERLLPGTIEKV--YPEPRSE 63
Query: 87 FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSV 135
+ + I +FL+ + F DL++G++ V +L+ L V
Sbjct: 64 SECLSNIREFLRGCG--ASLRLETFDANDLYQGQNFNKVLSSLVTLNKV 110
>gi|223718250 plastin 1 [Homo sapiens]
Length = 629
Score = 32.3 bits (72), Expect = 0.27
Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63
G S E + Y + + V+WI L+ D +H P + K L DG +LC
Sbjct: 107 GTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLC 166
Query: 64 KLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
K+IN L P I++ K+ F E ++ L +A G +I + DL EGK
Sbjct: 167 KMIN-LSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAS-DLKEGK 222
>gi|223718246 plastin 1 [Homo sapiens]
Length = 629
Score = 32.3 bits (72), Expect = 0.27
Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63
G S E + Y + + V+WI L+ D +H P + K L DG +LC
Sbjct: 107 GTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLC 166
Query: 64 KLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
K+IN L P I++ K+ F E ++ L +A G +I + DL EGK
Sbjct: 167 KMIN-LSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAS-DLKEGK 222
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 31.2 bits (69), Expect = 0.61
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 47 PGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESK--------MAFKQMEQISQFLK 98
P ++ L +G +L KL + P P+ KI + + + F+ + I+ +L
Sbjct: 53 PSPVELEESLRNGVLLAKL-GHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLS 111
Query: 99 AAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMAL 132
A G+ +T +T D+++ K+M V + AL
Sbjct: 112 AIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHAL 145
>gi|167614506 L-plastin [Homo sapiens]
Length = 627
Score = 30.0 bits (66), Expect = 1.4
Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 6/117 (5%)
Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQKWLM---DGTVLC 63
G S + + Y + + V+WI L+ D H P + DG VLC
Sbjct: 105 GTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLC 164
Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
K+IN P + + F E ++ L +A G +I DL EGK
Sbjct: 165 KMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNI-GAEDLKEGK 220
>gi|209862851 plastin 3 [Homo sapiens]
Length = 630
Score = 29.6 bits (65), Expect = 1.8
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63
G S E + Y + + V+WI L+ D H P + K + DG VLC
Sbjct: 108 GTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLC 167
Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
K+IN P + + F E ++ L +A G +I DL GK
Sbjct: 168 KMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNI-GAEDLRAGK 223
>gi|7549809 plastin 3 [Homo sapiens]
Length = 630
Score = 29.6 bits (65), Expect = 1.8
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63
G S E + Y + + V+WI L+ D H P + K + DG VLC
Sbjct: 108 GTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLC 167
Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120
K+IN P + + F E ++ L +A G +I DL GK
Sbjct: 168 KMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNI-GAEDLRAGK 223
>gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo
sapiens]
Length = 400
Score = 27.3 bits (59), Expect = 8.8
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 142 GCYRG-----EPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPR 196
GC RG EP R+A +NR S L G + G +GA AG G+PR
Sbjct: 340 GCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGS---GLPR 396
>gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo
sapiens]
Length = 400
Score = 27.3 bits (59), Expect = 8.8
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 142 GCYRG-----EPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPR 196
GC RG EP R+A +NR S L G + G +GA AG G+PR
Sbjct: 340 GCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGS---GLPR 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,279,082
Number of Sequences: 37866
Number of extensions: 363081
Number of successful extensions: 905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 868
Number of HSP's gapped (non-prelim): 37
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.