BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56549135 transgelin 3 [Homo sapiens] (199 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56549135 transgelin 3 [Homo sapiens] 410 e-115 gi|56549139 transgelin 3 [Homo sapiens] 410 e-115 gi|56549137 transgelin 3 [Homo sapiens] 410 e-115 gi|4507357 transgelin 2 [Homo sapiens] 301 3e-82 gi|48255907 transgelin [Homo sapiens] 282 2e-76 gi|48255905 transgelin [Homo sapiens] 282 2e-76 gi|4502923 calponin 3 [Homo sapiens] 145 2e-35 gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 142 1e-34 gi|4758018 calponin 2 isoform a [Homo sapiens] 134 4e-32 gi|41327730 calponin 2 isoform b [Homo sapiens] 114 7e-26 gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 42 4e-04 gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 41 6e-04 gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 41 6e-04 gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 41 8e-04 gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 39 0.004 gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 38 0.005 gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 38 0.005 gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 36 0.025 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 34 0.094 gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 34 0.094 gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 34 0.094 gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 32 0.27 gi|223718250 plastin 1 [Homo sapiens] 32 0.27 gi|223718246 plastin 1 [Homo sapiens] 32 0.27 gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 31 0.61 gi|167614506 L-plastin [Homo sapiens] 30 1.4 gi|209862851 plastin 3 [Homo sapiens] 30 1.8 gi|7549809 plastin 3 [Homo sapiens] 30 1.8 gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo ... 27 8.8 gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo ... 27 8.8 >gi|56549135 transgelin 3 [Homo sapiens] Length = 199 Score = 410 bits (1053), Expect = e-115 Identities = 199/199 (100%), Positives = 199/199 (100%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NKGASQAGMTGYGMPRQIM 199 NKGASQAGMTGYGMPRQIM Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|56549139 transgelin 3 [Homo sapiens] Length = 199 Score = 410 bits (1053), Expect = e-115 Identities = 199/199 (100%), Positives = 199/199 (100%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NKGASQAGMTGYGMPRQIM 199 NKGASQAGMTGYGMPRQIM Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|56549137 transgelin 3 [Homo sapiens] Length = 199 Score = 410 bits (1053), Expect = e-115 Identities = 199/199 (100%), Positives = 199/199 (100%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK Sbjct: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS Sbjct: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 Query: 181 NKGASQAGMTGYGMPRQIM 199 NKGASQAGMTGYGMPRQIM Sbjct: 181 NKGASQAGMTGYGMPRQIM 199 >gi|4507357 transgelin 2 [Homo sapiens] Length = 199 Score = 301 bits (770), Expect = 3e-82 Identities = 139/199 (69%), Positives = 169/199 (84%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MANRGP+YGLSREVQ+KIE++YDADLE L+ WI QC +D+ P PGR +FQ WL DGT Sbjct: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60 Query: 61 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 VLC+LIN+LYP GQ P+ KI S MAFKQMEQISQFL+AAE YG+ TTDIFQTVDLWEGK Sbjct: 61 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK 120 Query: 121 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS 180 +MA VQRTLM LG +AV +DDG + G+P+WF +K+++N R FS+ QL++G+NVIGLQMG+ Sbjct: 121 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT 180 Query: 181 NKGASQAGMTGYGMPRQIM 199 N+GASQAGMTGYGMPRQI+ Sbjct: 181 NRGASQAGMTGYGMPRQIL 199 >gi|48255907 transgelin [Homo sapiens] Length = 201 Score = 282 bits (721), Expect = 2e-76 Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60 Query: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118 +L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E Sbjct: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119 Query: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178 GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM Sbjct: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179 Query: 179 GSNKGASQAGMTGYGMPRQIM 199 GSN+GASQAGMTGYG PRQI+ Sbjct: 180 GSNRGASQAGMTGYGRPRQII 200 >gi|48255905 transgelin [Homo sapiens] Length = 201 Score = 282 bits (721), Expect = 2e-76 Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%) Query: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60 MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60 Query: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118 +L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E Sbjct: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119 Query: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178 GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM Sbjct: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179 Query: 179 GSNKGASQAGMTGYGMPRQIM 199 GSN+GASQAGMTGYG PRQI+ Sbjct: 180 GSNRGASQAGMTGYGRPRQII 200 >gi|4502923 calponin 3 [Homo sapiens] Length = 329 Score = 145 bits (367), Expect = 2e-35 Identities = 88/203 (43%), Positives = 119/203 (58%), Gaps = 26/203 (12%) Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62 N+GPSYGLS EV+ KI KYD E L +WI E++ G +FQ L DG +L Sbjct: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWI-----EEVTGMSIG-PNFQLGLKDGIIL 58 Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122 C+LIN L P + K++ES + + Q+E I F+KA + YG++ DIF+ DL+E +M Sbjct: 59 CELINKLQPGS---VKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115 Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFH-------RKAQQNRRGFSEEQLRQGQNVIG 175 VQ TL+AL +A TK FH + A++ R F E +L+ GQ+VIG Sbjct: 116 TQVQTTLVALAGLAKTKG----------FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIG 165 Query: 176 LQMGSNKGASQAGMTGYGMPRQI 198 LQMG+NK ASQAGMT YG R + Sbjct: 166 LQMGTNKCASQAGMTAYGTRRHL 188 Score = 35.8 bits (81), Expect = 0.025 Identities = 16/27 (59%), Positives = 21/27 (77%) Query: 172 NVIGLQMGSNKGASQAGMTGYGMPRQI 198 + I LQMG+NK ASQ GM+ YG+ RQ+ Sbjct: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267 >gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] Length = 297 Score = 142 bits (359), Expect = 1e-34 Identities = 85/196 (43%), Positives = 115/196 (58%), Gaps = 14/196 (7%) Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62 NRGP+YGLS EV+ K+ QKYD E +L +WI E + G +F L DG +L Sbjct: 7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWI-----EGVTGRRIGN-NFMDGLKDGIIL 60 Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122 C+ IN L P + KI+ES + Q+E I F+KA YGV+ DIF+ DL+E + Sbjct: 61 CEFINKLQPGS---VKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNH 117 Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182 VQ TL+AL S+A TK + G + A++ R F +LR+G+N+IGLQMG+NK Sbjct: 118 TQVQSTLLALASMAKTKGNKVNVGV-----KYAEKQERKFEPGKLREGRNIIGLQMGTNK 172 Query: 183 GASQAGMTGYGMPRQI 198 ASQ GMT YG R + Sbjct: 173 FASQQGMTAYGTRRHL 188 Score = 44.7 bits (104), Expect = 5e-05 Identities = 19/25 (76%), Positives = 22/25 (88%) Query: 174 IGLQMGSNKGASQAGMTGYGMPRQI 198 + LQMGSNKGASQ GMT YG+PRQ+ Sbjct: 243 VSLQMGSNKGASQRGMTVYGLPRQV 267 >gi|4758018 calponin 2 isoform a [Homo sapiens] Length = 309 Score = 134 bits (338), Expect = 4e-32 Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 12/196 (6%) Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62 N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60 Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122 C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M Sbjct: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117 Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182 VQ +L+AL A TK G G + +++ R F + ++ GQ VIGLQMG+NK Sbjct: 118 TQVQVSLLALAGKAKTK--GLQSGVDIGV-KYSEKQERNFDDATMKAGQCVIGLQMGTNK 174 Query: 183 GASQAGMTGYGMPRQI 198 ASQ+GMT YG R + Sbjct: 175 CASQSGMTAYGTRRHL 190 >gi|41327730 calponin 2 isoform b [Homo sapiens] Length = 270 Score = 114 bits (284), Expect = 7e-26 Identities = 74/196 (37%), Positives = 104/196 (53%), Gaps = 11/196 (5%) Query: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62 N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60 Query: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122 C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M Sbjct: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117 Query: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182 VQ +L+AL T G ++ R+ + + + + I LQMG+NK Sbjct: 118 TQVQVSLLALAGKMGTNKCASQSGMTAYGTRRHLYDPKNHILPPM--DHSTISLQMGTNK 175 Query: 183 GASQAGMTGYGMPRQI 198 ASQ GMT G R I Sbjct: 176 CASQVGMTAPGTRRHI 191 >gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] Length = 1349 Score = 41.6 bits (96), Expect = 4e-04 Identities = 33/109 (30%), Positives = 49/109 (44%), Gaps = 14/109 (12%) Query: 52 FQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIF 111 F+ L +G +LC LIN L P I KI+ ++ I+ FLKA E G++ +F Sbjct: 87 FRASLENGVLLCDLINKLKP---GVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLF 143 Query: 112 QTVDLWEGKDMAAV--QRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQN 158 DL + + V + T + +V +T W RKAQ N Sbjct: 144 HPGDLQDLSNRVTVKQEETDRRVKNVLITL---------YWLGRKAQSN 183 >gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] Length = 845 Score = 41.2 bits (95), Expect = 6e-04 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Query: 56 LMDGTVLCKLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLK-AAETYGVRTTDIFQT 113 L DG +LC+L+N+L P +M+ F ++ I FL E +G++ +++F+ Sbjct: 37 LRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEA 96 Query: 114 VDLWEGKDMAAVQRTLMALGSVAVTKDDG 142 DL++ +D V TL AL + ++ G Sbjct: 97 FDLFDVQDFGKVIYTLSALSWTPIAQNRG 125 >gi|33859670 leucine-rich repeats and calponin homology (CH) domain containing 1 [Homo sapiens] Length = 728 Score = 41.2 bits (95), Expect = 6e-04 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 18/138 (13%) Query: 6 PSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKL 65 P + + R++++ E+K +L +L + I ++ + H G A LMDG VLC L Sbjct: 565 PQFTIRRKMEQMREEK---ELVEQLRESIEMRLKVSL-HEDLGAA-----LMDGVVLCHL 615 Query: 66 INSLYPPG----QEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKD 121 +N + P P P + + MA K + FL+A GV D+ D+ + D Sbjct: 616 VNHIRPRSVASIHVPSPAVPKLSMA-KCRRNVENFLEACRKLGVPEADLCSPCDILQ-LD 673 Query: 122 MAAVQR---TLMALGSVA 136 +++ TL+ALG A Sbjct: 674 FRHIRKTVDTLLALGEKA 691 >gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 [Homo sapiens] Length = 847 Score = 40.8 bits (94), Expect = 8e-04 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 10/93 (10%) Query: 56 LMDGTVLCKLINSL--YPPGQEPI---PKISESKMAFKQMEQISQFLKAA-ETYGVRTTD 109 L DG +LC+L+N+L + + I P++S+ F ++ I FL A ET+G+R ++ Sbjct: 37 LRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ----FLCLKNIRTFLTACCETFGMRKSE 92 Query: 110 IFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDG 142 +F+ DL++ +D V TL L + G Sbjct: 93 LFEAFDLFDVRDFGKVIETLSRLSRTPIALATG 125 >gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo sapiens] Length = 776 Score = 38.5 bits (88), Expect = 0.004 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 7/108 (6%) Query: 27 ENKLVDWII-LQCAEDIEHPPPGRAHFQKW-LMDGTVLCKLINSLYPPGQEPIPKISESK 84 E ++V W+I L E + F K L +G VLCKLIN L P E + + Sbjct: 4 EEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKF--CLDPQ 61 Query: 85 MAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMAL 132 + I+ FLK T V +IF DL+ G + + V TL+A+ Sbjct: 62 TEADCINNINDFLKGCATLQV---EIFDPDDLYSGVNFSKVLSTLLAV 106 >gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 [Homo sapiens] Length = 878 Score = 38.1 bits (87), Expect = 0.005 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Query: 56 LMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAA-ETYGVRTTDIFQ 112 L DG +LC+L+++L PG + I+ F ++ I FLK + +G+R +++F Sbjct: 37 LRDGVLLCQLLHNL-SPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95 Query: 113 TVDLWE----GKDMAAVQRTLMALGSVAVTK 139 DL++ GK ++AV R ++L S+A K Sbjct: 96 PFDLFDVRDFGKVISAVSR--LSLHSIAQNK 124 >gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [Homo sapiens] Length = 839 Score = 38.1 bits (87), Expect = 0.005 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Query: 56 LMDGTVLCKLINSLYPPGQEPIPKIS--ESKMAFKQMEQISQFLKAA-ETYGVRTTDIFQ 112 L DG +LC+L+++L PG + I+ F ++ I FLK + +G+R +++F Sbjct: 37 LRDGVLLCQLLHNL-SPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFD 95 Query: 113 TVDLWE----GKDMAAVQRTLMALGSVAVTK 139 DL++ GK ++AV R ++L S+A K Sbjct: 96 PFDLFDVRDFGKVISAVSR--LSLHSIAQNK 124 >gi|154091020 leucine-rich repeats and calponin homology (CH) domain containing 2 [Homo sapiens] Length = 765 Score = 35.8 bits (81), Expect = 0.025 Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 20/132 (15%) Query: 12 REVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYP 71 RE +E+I Q L N L + + +DI G A LMDG VLC L N + P Sbjct: 643 REEREQIRQ-----LRNNLESRLKVILPDDI-----GAA-----LMDGVVLCHLANHIRP 687 Query: 72 PG----QEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQR 127 P P + + MA K + FL A + GV + + E + + V Sbjct: 688 RSVASIHVPSPAVPKLSMA-KCRRNVENFLDACKKLGVSQERLCLPHHILEERGLVKVGV 746 Query: 128 TLMALGSVAVTK 139 T+ AL + TK Sbjct: 747 TVQALLELPTTK 758 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 33.9 bits (76), Expect = 0.094 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107 G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKDMAAVQ 126 + +F DL + + V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|163310743 LIM and calponin homology domains 1 isoform b [Homo sapiens] Length = 1057 Score = 33.9 bits (76), Expect = 0.094 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107 G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKDMAAVQ 126 + +F DL + + V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|163310741 LIM and calponin homology domains 1 isoform a [Homo sapiens] Length = 1083 Score = 33.9 bits (76), Expect = 0.094 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 48 GRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRT 107 G F+ L +G +LC+L+N++ P + KI+ ++ I FL+ + G++ Sbjct: 40 GDKDFRTGLENGILLCELLNAIKP---GLVKKINRLPTPIAGLDNIILFLRGCKELGLKE 96 Query: 108 TDIFQTVDLWEGKDMAAVQ 126 + +F DL + + V+ Sbjct: 97 SQLFDPSDLQDTSNRVTVK 115 >gi|22027528 PAK-interacting exchange factor beta isoform b [Homo sapiens] Length = 782 Score = 32.3 bits (72), Expect = 0.27 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 31 VDWII----LQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMA 86 V W+I L+ + P G Q L DG VLC+L+ L P E + E + Sbjct: 8 VTWLITLGVLESPKKTISDPEG--FLQASLKDGVVLCRLLERLLPGTIEKV--YPEPRSE 63 Query: 87 FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSV 135 + + I +FL+ + F DL++G++ V +L+ L V Sbjct: 64 SECLSNIREFLRGCG--ASLRLETFDANDLYQGQNFNKVLSSLVTLNKV 110 >gi|223718250 plastin 1 [Homo sapiens] Length = 629 Score = 32.3 bits (72), Expect = 0.27 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 8/118 (6%) Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63 G S E + Y + + V+WI L+ D +H P + K L DG +LC Sbjct: 107 GTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLC 166 Query: 64 KLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 K+IN L P I++ K+ F E ++ L +A G +I + DL EGK Sbjct: 167 KMIN-LSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAS-DLKEGK 222 >gi|223718246 plastin 1 [Homo sapiens] Length = 629 Score = 32.3 bits (72), Expect = 0.27 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 8/118 (6%) Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63 G S E + Y + + V+WI L+ D +H P + K L DG +LC Sbjct: 107 GTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLC 166 Query: 64 KLINSLYPPGQEPIPKISESKMA-FKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 K+IN L P I++ K+ F E ++ L +A G +I + DL EGK Sbjct: 167 KMIN-LSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGAS-DLKEGK 222 >gi|39753961 IQ motif containing GTPase activating protein 3 [Homo sapiens] Length = 1631 Score = 31.2 bits (69), Expect = 0.61 Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 9/94 (9%) Query: 47 PGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESK--------MAFKQMEQISQFLK 98 P ++ L +G +L KL + P P+ KI + + + F+ + I+ +L Sbjct: 53 PSPVELEESLRNGVLLAKL-GHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLS 111 Query: 99 AAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMAL 132 A G+ +T +T D+++ K+M V + AL Sbjct: 112 AIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHAL 145 >gi|167614506 L-plastin [Homo sapiens] Length = 627 Score = 30.0 bits (66), Expect = 1.4 Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 6/117 (5%) Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQKWLM---DGTVLC 63 G S + + Y + + V+WI L+ D H P + DG VLC Sbjct: 105 GTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLC 164 Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 K+IN P + + F E ++ L +A G +I DL EGK Sbjct: 165 KMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNI-GAEDLKEGK 220 >gi|209862851 plastin 3 [Homo sapiens] Length = 630 Score = 29.6 bits (65), Expect = 1.8 Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 6/117 (5%) Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63 G S E + Y + + V+WI L+ D H P + K + DG VLC Sbjct: 108 GTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLC 167 Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 K+IN P + + F E ++ L +A G +I DL GK Sbjct: 168 KMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNI-GAEDLRAGK 223 >gi|7549809 plastin 3 [Homo sapiens] Length = 630 Score = 29.6 bits (65), Expect = 1.8 Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 6/117 (5%) Query: 9 GLSREVQEKIEQKYDADLENKLVDWI--ILQCAEDIEHPPPGRAHFQ---KWLMDGTVLC 63 G S E + Y + + V+WI L+ D H P + K + DG VLC Sbjct: 108 GTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLC 167 Query: 64 KLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK 120 K+IN P + + F E ++ L +A G +I DL GK Sbjct: 168 KMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNI-GAEDLRAGK 223 >gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo sapiens] Length = 400 Score = 27.3 bits (59), Expect = 8.8 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 8/60 (13%) Query: 142 GCYRG-----EPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPR 196 GC RG EP R+A +NR S L G + G +GA AG G+PR Sbjct: 340 GCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGS---GLPR 396 >gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo sapiens] Length = 400 Score = 27.3 bits (59), Expect = 8.8 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 8/60 (13%) Query: 142 GCYRG-----EPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPR 196 GC RG EP R+A +NR S L G + G +GA AG G+PR Sbjct: 340 GCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGS---GLPR 396 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,279,082 Number of Sequences: 37866 Number of extensions: 363081 Number of successful extensions: 905 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 868 Number of HSP's gapped (non-prelim): 37 length of query: 199 length of database: 18,247,518 effective HSP length: 97 effective length of query: 102 effective length of database: 14,574,516 effective search space: 1486600632 effective search space used: 1486600632 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.