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Search of human proteins with 56117854
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56117854 hematopoietic cell signal transducer isoform 2
precursor [Homo sapiens]
(92 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56117854 hematopoietic cell signal transducer isoform 2 precu... 185 8e-48
gi|15826850 hematopoietic cell signal transducer isoform 1 precu... 180 2e-46
gi|4506321 protein tyrosine phosphatase, receptor type, N precur... 31 0.19
gi|38158005 TYRO protein tyrosine kinase binding protein isoform... 30 0.32
gi|4507755 TYRO protein tyrosine kinase binding protein isoform ... 30 0.32
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti... 30 0.55
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens] 28 1.2
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 28 1.6
gi|55741675 hypothetical protein LOC22889 [Homo sapiens] 28 2.1
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 28 2.1
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 28 2.1
gi|62912474 leucine-rich repeat-containing G protein-coupled rec... 28 2.1
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 27 2.7
gi|134304838 eukaryotic translation initiation factor 2-alpha ki... 27 2.7
gi|48976054 hypothetical protein LOC79886 [Homo sapiens] 27 2.7
gi|4507157 sortilin-related receptor containing LDLR class A rep... 27 3.5
gi|5174419 caseinolytic peptidase, ATP-dependent, proteolytic su... 27 4.6
gi|154146199 sal-like 3 [Homo sapiens] 27 4.6
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 27 4.6
gi|239751796 PREDICTED: hypothetical protein XP_002348004 [Homo ... 26 6.1
gi|239747084 PREDICTED: hypothetical protein XP_002343912 [Homo ... 26 6.1
gi|239746287 PREDICTED: hypothetical protein XP_002343724 [Homo ... 26 6.1
gi|205360981 resistance to inhibitors of cholinesterase 3 homolo... 26 6.1
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 26 6.1
gi|145309320 forkhead box Q1 [Homo sapiens] 26 7.9
gi|91199550 CD68 antigen isoform B [Homo sapiens] 26 7.9
gi|91199548 CD68 antigen isoform A [Homo sapiens] 26 7.9
gi|11641269 dipeptidase 2 precursor [Homo sapiens] 26 7.9
gi|32698864 hypothetical protein LOC149466 [Homo sapiens] 26 7.9
>gi|56117854 hematopoietic cell signal transducer isoform 2
precursor [Homo sapiens]
Length = 92
Score = 185 bits (469), Expect = 8e-48
Identities = 92/92 (100%), Positives = 92/92 (100%)
Query: 1 MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA 60
MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA
Sbjct: 1 MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA 60
Query: 61 SLLIVGAVFLCARPRRSPAQDGKVYINMPGRG 92
SLLIVGAVFLCARPRRSPAQDGKVYINMPGRG
Sbjct: 61 SLLIVGAVFLCARPRRSPAQDGKVYINMPGRG 92
>gi|15826850 hematopoietic cell signal transducer isoform 1
precursor [Homo sapiens]
Length = 93
Score = 180 bits (457), Expect = 2e-46
Identities = 92/93 (98%), Positives = 92/93 (98%), Gaps = 1/93 (1%)
Query: 1 MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA 60
MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA
Sbjct: 1 MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVA 60
Query: 61 SLLIVGAVFLCARPRRSPAQ-DGKVYINMPGRG 92
SLLIVGAVFLCARPRRSPAQ DGKVYINMPGRG
Sbjct: 61 SLLIVGAVFLCARPRRSPAQEDGKVYINMPGRG 93
>gi|4506321 protein tyrosine phosphatase, receptor type, N precursor
[Homo sapiens]
Length = 979
Score = 31.2 bits (69), Expect = 0.19
Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 19 QTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCAR 73
QT G+R A P T+ S S S+ L L VA VA LL+ AV LC R
Sbjct: 551 QTGVGQREEAAAVLPQTAHSTSPMRSVLLTL----VALAGVAGLLVALAVALCVR 601
>gi|38158005 TYRO protein tyrosine kinase binding protein isoform
2 precursor [Homo sapiens]
Length = 112
Score = 30.4 bits (67), Expect = 0.32
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 7/64 (10%)
Query: 10 LLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVF 69
LLLLP+ A S L CS C ++S +LAG+V D V ++LI AV+
Sbjct: 10 LLLLPLLLAV------SGLRPVQAQAQSDCS-CSTVSPGVLAGIVMGDLVLTVLIALAVY 62
Query: 70 LCAR 73
R
Sbjct: 63 FLGR 66
>gi|4507755 TYRO protein tyrosine kinase binding protein isoform 1
precursor [Homo sapiens]
Length = 113
Score = 30.4 bits (67), Expect = 0.32
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 7/64 (10%)
Query: 10 LLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVF 69
LLLLP+ A S L CS C ++S +LAG+V D V ++LI AV+
Sbjct: 10 LLLLPLLLAV------SGLRPVQAQAQSDCS-CSTVSPGVLAGIVMGDLVLTVLIALAVY 62
Query: 70 LCAR 73
R
Sbjct: 63 FLGR 66
>gi|4757886 pituitary tumor-transforming gene 1
protein-interacting protein precursor [Homo sapiens]
Length = 180
Score = 29.6 bits (65), Expect = 0.55
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 5/38 (13%)
Query: 5 GHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGC 42
G L LLL+PVAAAQ PG S T+ +C C
Sbjct: 19 GAALLLLLIPVAAAQEPPGAACS-----QNTNKTCEEC 51
>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
Length = 1235
Score = 28.5 bits (62), Expect = 1.2
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 4/64 (6%)
Query: 7 ILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSG----CGSLSLPLLAGLVAADAVASL 62
+L LLLLP+ AAQ G +++L A G G + C +L LP L+ A A
Sbjct: 968 LLLLLLLPLLAAQGGGGLQAALLALEVGLVGLGASYLLLCTALHLPSSLFLLLAQGTALG 1027
Query: 63 LIVG 66
++G
Sbjct: 1028 AVLG 1031
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 39 CSGCGSLSLPLLAGLVAADAVASL 62
CS CG++ PLL+ A +A+ASL
Sbjct: 1131 CSACGAVPSPLLSSASARNAMASL 1154
>gi|55741675 hypothetical protein LOC22889 [Homo sapiens]
Length = 614
Score = 27.7 bits (60), Expect = 2.1
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 19 QTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCARPRRSP 78
Q P LP PG + SG GS A A DA A++ L A+ + P
Sbjct: 20 QPAPAPLLFLPPAAPGGEVTSSG-GSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKP 78
Query: 79 AQDGKVYINMPGRG 92
Q+ + PG+G
Sbjct: 79 TQNASEKLQAPGKG 92
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 27.7 bits (60), Expect = 2.1
Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 4 LGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLL 63
LG +LLL +AA Q + S + A+ S G L LAGL AA +AS+
Sbjct: 599 LGSEASVLLLTLAAVQCSVSV-SCVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLASVG 657
Query: 64 IVGAVFLC---ARPRRSPAQDG 82
GA LC A P PA G
Sbjct: 658 EYGASPLCLPYAPPEGQPAALG 679
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 27.7 bits (60), Expect = 2.1
Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 4 LGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLL 63
LG +LLL +AA Q + S + A+ S G L LAGL AA +AS+
Sbjct: 651 LGSEASVLLLTLAAVQCSVSV-SCVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLASVG 709
Query: 64 IVGAVFLC---ARPRRSPAQDG 82
GA LC A P PA G
Sbjct: 710 EYGASPLCLPYAPPEGQPAALG 731
>gi|62912474 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 3 [Homo sapiens]
Length = 828
Score = 27.7 bits (60), Expect = 2.1
Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 4 LGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLL 63
LG +LLL +AA Q + S + A+ S G L LAGL AA +AS+
Sbjct: 512 LGSEASVLLLTLAAVQCSVSV-SCVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLASVG 570
Query: 64 IVGAVFLC---ARPRRSPAQDG 82
GA LC A P PA G
Sbjct: 571 EYGASPLCLPYAPPEGQPAALG 592
>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
sapiens]
Length = 828
Score = 27.3 bits (59), Expect = 2.7
Identities = 13/32 (40%), Positives = 14/32 (43%)
Query: 12 LLPVAAAQTTPGERSSLPAFYPGTSGSCSGCG 43
L AA P S + GTSG C GCG
Sbjct: 789 LCTTGAAPPPPASASFVGISCAGTSGGCDGCG 820
>gi|134304838 eukaryotic translation initiation factor 2-alpha
kinase 3 [Homo sapiens]
Length = 1116
Score = 27.3 bits (59), Expect = 2.7
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 7 ILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLV-AADAVAS 61
+L LLLL +AA G LPA T+ + G G+ + P A V AA AVA+
Sbjct: 15 LLLLLLLGLAARTVAAGRARGLPA---PTAEAAFGLGAAAAPTSATRVPAAGAVAA 67
>gi|48976054 hypothetical protein LOC79886 [Homo sapiens]
Length = 361
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 16 AAAQTTPGERSSLPAFYPGTSGSCSGCGS 44
AAA P +PA G+SGS SGCGS
Sbjct: 20 AAALAAP---DIVPALASGSSGSTSGCGS 45
>gi|4507157 sortilin-related receptor containing LDLR class A repeats
preproprotein [Homo sapiens]
Length = 2214
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 14/57 (24%)
Query: 20 TTPGERSSLPAFYPGTSGSC--------------SGCGSLSLPLLAGLVAADAVASL 62
+TPG + LP +Y +SG+C G + PLLA + AA L
Sbjct: 1412 STPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQL 1468
>gi|5174419 caseinolytic peptidase, ATP-dependent, proteolytic
subunit precursor [Homo sapiens]
Length = 277
Score = 26.6 bits (57), Expect = 4.6
Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
Query: 57 DAVASLLIVGAVFLCARPRRSPAQDGKVYINMPG 90
D+VASL+I +FL + + P +YIN PG
Sbjct: 93 DSVASLVIAQLLFLQSESNKKPIH---MYINSPG 123
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 26.6 bits (57), Expect = 4.6
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 2/79 (2%)
Query: 2 IHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGC--GSLSLPLLAGLVAADAV 59
IH ++ + VA Q P S PA P G G +LPL AG AA
Sbjct: 217 IHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIA 276
Query: 60 ASLLIVGAVFLCARPRRSP 78
S A F A+P P
Sbjct: 277 GSGPAAPAAFEGAQPLSRP 295
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 26.6 bits (57), Expect = 4.6
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 27 SLPAFYPGTSGSCSGCGSLS--LPLLAGLVAADAVASLLIVGAVFLCARPRR 76
S PA + TS SG L LPL+ G A V + +V +C R +R
Sbjct: 535 SRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQR 586
>gi|239751796 PREDICTED: hypothetical protein XP_002348004 [Homo
sapiens]
Length = 291
Score = 26.2 bits (56), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 25 RSSLPAFYPGTSGSCSGCGSLSL-PLLAGLVA-ADAVASLLIVGAVF 69
R+ LP PG+S G + SL P +AG A V L+V A+F
Sbjct: 34 RTELPEHSPGSSSQVPGAAAHSLRPYIAGAGAGCQLVLQQLLVEAIF 80
>gi|239747084 PREDICTED: hypothetical protein XP_002343912 [Homo
sapiens]
Length = 313
Score = 26.2 bits (56), Expect = 6.1
Identities = 11/19 (57%), Positives = 12/19 (63%)
Query: 73 RPRRSPAQDGKVYINMPGR 91
RPRRSPA+ G N P R
Sbjct: 95 RPRRSPAEPGSARRNRPAR 113
>gi|239746287 PREDICTED: hypothetical protein XP_002343724 [Homo
sapiens]
Length = 291
Score = 26.2 bits (56), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 25 RSSLPAFYPGTSGSCSGCGSLSL-PLLAGLVA-ADAVASLLIVGAVF 69
R+ LP PG+S G + SL P +AG A V L+V A+F
Sbjct: 34 RTELPEHSPGSSSQVPGAAAHSLRPYIAGAGAGCQLVLQQLLVEAIF 80
>gi|205360981 resistance to inhibitors of cholinesterase 3 homolog
isoform a [Homo sapiens]
Length = 368
Score = 26.2 bits (56), Expect = 6.1
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 5/75 (6%)
Query: 21 TPG---ERSSLPAFYPGTSGSCSGCGS--LSLPLLAGLVAADAVASLLIVGAVFLCARPR 75
TPG +RS L + GS G G L+ ++ L + +
Sbjct: 62 TPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKG 121
Query: 76 RSPAQDGKVYINMPG 90
++ A+DGK Y MPG
Sbjct: 122 KTTAEDGKCYTAMPG 136
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 26.2 bits (56), Expect = 6.1
Identities = 18/51 (35%), Positives = 22/51 (43%)
Query: 15 VAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIV 65
VA Q +R SL Y GT GC S+ L VA A A L ++
Sbjct: 523 VADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLI 573
>gi|145309320 forkhead box Q1 [Homo sapiens]
Length = 403
Score = 25.8 bits (55), Expect = 7.9
Identities = 14/36 (38%), Positives = 18/36 (50%)
Query: 13 LPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLP 48
+P AAA E + A PG G+ SG G+ S P
Sbjct: 78 IPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKP 113
>gi|91199550 CD68 antigen isoform B [Homo sapiens]
Length = 327
Score = 25.8 bits (55), Expect = 7.9
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 34 GTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCARPRRSPA 79
G S SC S+ LPL+ GL+ +A +LI + RR P+
Sbjct: 282 GQSFSCPSDRSILLPLIIGLILLGLLALVLIAFCII-----RRRPS 322
>gi|91199548 CD68 antigen isoform A [Homo sapiens]
Length = 354
Score = 25.8 bits (55), Expect = 7.9
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 34 GTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCARPRRSPA 79
G S SC S+ LPL+ GL+ +A +LI + RR P+
Sbjct: 309 GQSFSCPSDRSILLPLIIGLILLGLLALVLIAFCII-----RRRPS 349
>gi|11641269 dipeptidase 2 precursor [Homo sapiens]
Length = 486
Score = 25.8 bits (55), Expect = 7.9
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 10/54 (18%)
Query: 7 ILFLLLLPVAAAQTTPGERSSLPAF-------YPGTSGSCSGCGSLSLPLLAGL 53
+L LLL PV A TTPG +L PGT + +LS P GL
Sbjct: 22 LLLLLLQPVTCAYTTPGPPRALTTLGAPRAHTMPGTYAPST---TLSSPSTQGL 72
>gi|32698864 hypothetical protein LOC149466 [Homo sapiens]
Length = 113
Score = 25.8 bits (55), Expect = 7.9
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 7/54 (12%)
Query: 22 PGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAV--FLCAR 73
P E + A PG G G+ + P+L G V V SLLI A LC R
Sbjct: 11 PSELPTASAVAPGP-----GTGARAWPVLVGFVLGAVVLSLLIALAAKCHLCRR 59
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,021,473
Number of Sequences: 37866
Number of extensions: 160287
Number of successful extensions: 516
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 504
Number of HSP's gapped (non-prelim): 30
length of query: 92
length of database: 18,247,518
effective HSP length: 63
effective length of query: 29
effective length of database: 15,861,960
effective search space: 459996840
effective search space used: 459996840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.