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Search of human proteins with 56117838
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens] 661 0.0
gi|188528609 secreted frizzled-related protein 5 [Homo sapiens] 356 2e-98
gi|48475052 secreted frizzled-related protein 2 precursor [Homo ... 233 2e-61
gi|4503833 frizzled 7 [Homo sapiens] 105 5e-23
gi|4503825 frizzled 1 [Homo sapiens] 103 2e-22
gi|22547161 frizzled 4 [Homo sapiens] 102 4e-22
gi|4503827 frizzled 2 [Homo sapiens] 101 1e-21
gi|6005762 frizzled 10 [Homo sapiens] 101 1e-21
gi|4503835 frizzled 9 [Homo sapiens] 98 1e-20
gi|13994190 frizzled 8 [Homo sapiens] 93 3e-19
gi|27894385 frizzled 5 precursor [Homo sapiens] 92 8e-19
gi|38455388 frizzled-related protein [Homo sapiens] 91 2e-18
gi|170784838 secreted frizzled-related protein 4 [Homo sapiens] 88 1e-17
gi|8393378 frizzled 3 [Homo sapiens] 87 3e-17
gi|34734079 frizzled 6 [Homo sapiens] 81 1e-15
gi|29244926 corin [Homo sapiens] 73 4e-13
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 64 2e-10
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 64 2e-10
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 63 4e-10
gi|13899255 membrane frizzled-related protein [Homo sapiens] 54 2e-07
gi|5032099 smoothened [Homo sapiens] 49 8e-06
gi|7662020 hypothetical protein LOC9766 [Homo sapiens] 35 0.086
gi|67782358 complement factor B preproprotein [Homo sapiens] 33 0.25
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 33 0.25
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 32 0.73
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 32 0.73
gi|73695473 roquin [Homo sapiens] 32 0.96
gi|149408135 ret finger protein-like 3 isoform 1 [Homo sapiens] 31 1.2
gi|5730013 ret finger protein-like 3 isoform 2 [Homo sapiens] 31 1.2
gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens] 30 2.1
>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
Length = 314
Score = 661 bits (1706), Expect = 0.0
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MGIGRSEGGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVD 60
MGIGRSEGGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVD
Sbjct: 1 MGIGRSEGGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVD 60
Query: 61 IPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPV 120
IPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPV
Sbjct: 61 IPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPV 120
Query: 121 CLDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKP 180
CLDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKP
Sbjct: 121 CLDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKP 180
Query: 181 QGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKK 240
QGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKK
Sbjct: 181 QGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKK 240
Query: 241 KDLKKLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKK 300
KDLKKLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKK
Sbjct: 241 KDLKKLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKK 300
Query: 301 MKNHECPTFQSVFK 314
MKNHECPTFQSVFK
Sbjct: 301 MKNHECPTFQSVFK 314
>gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
Length = 317
Score = 356 bits (913), Expect = 2e-98
Identities = 178/309 (57%), Positives = 228/309 (73%), Gaps = 9/309 (2%)
Query: 8 GGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRL 67
GG R AAL +LL GA A EYDY +Q++ P GR Y+KPPQC+DIPADL L
Sbjct: 8 GGVRTAALALLL--GALHWAPARCEEYDYYGWQAE--PLH-GRSYSKPPQCLDIPADLPL 62
Query: 68 CHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDRPIY 127
CH VGYK+M LPNLLEHE++AEVKQQASSW+PLL K CH+ TQVFLCSLFAPVCLDRPIY
Sbjct: 63 CHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIY 122
Query: 128 PCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP-EGDVCIAMTPPNATEASKPQGTTVC 186
PCR LCEAVR C P+M+ +GF WPEML C KFP + D+CIA+ + A+ P T +C
Sbjct: 123 PCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGH-LPATAPPVTKIC 181
Query: 187 PPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIV--PKKKKPLKLGPIKKKDLK 244
C+ E ++ ++E +C+S+F ++M+IKE+K ENGD+K++ KKKK LK GP+K+KD K
Sbjct: 182 AQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTK 241
Query: 245 KLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKKMKNH 304
+LVL++KNGA CPC QLD+L+ FL+MGRKV Q LL A+++WDKKNKE K +K M ++
Sbjct: 242 RLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSY 301
Query: 305 ECPTFQSVF 313
C + F
Sbjct: 302 PCSLYYPFF 310
>gi|48475052 secreted frizzled-related protein 2 precursor [Homo
sapiens]
Length = 295
Score = 233 bits (593), Expect = 2e-61
Identities = 112/263 (42%), Positives = 166/263 (63%), Gaps = 7/263 (2%)
Query: 51 FYTKPPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQ 110
F K C IPA+L+LCH + Y+ M LPNLL HETM EV +QA +W+PL+ K CH T+
Sbjct: 33 FSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTK 92
Query: 111 VFLCSLFAPVC---LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP-EGDVC 166
FLCSLFAPVC LD I PC LC V+D C PVM FGF WP+ML+CD+FP + D+C
Sbjct: 93 KFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLC 152
Query: 167 IAMTPPNATEASKPQGTTVCPPCDNELKSE-AIIEHLCASEFALRMKIKEVKKENGDKKI 225
I + + + + VC C N+ + I+E LC ++FAL++K+KE+ N D KI
Sbjct: 153 IPLASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKI 212
Query: 226 V--PKKKKPLKLGPIKKKDLKKLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTA 283
+ K K KL + ++DLKK VL+LK+ C C ++++++ +L+MG+K + ++T+
Sbjct: 213 ILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITS 272
Query: 284 IHKWDKKNKEFKNFMKKMKNHEC 306
+ +W K +EFK + ++ +C
Sbjct: 273 VKRWQKGQREFKRISRSIRKLQC 295
>gi|4503833 frizzled 7 [Homo sapiens]
Length = 574
Score = 105 bits (262), Expect = 5e-23
Identities = 57/155 (36%), Positives = 79/155 (50%), Gaps = 13/155 (8%)
Query: 18 LLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRLCHNVGYKKMV 77
L AL ALL SA + PY + + P P + LC ++ Y + +
Sbjct: 15 LCALVLALLGALSAG--------AGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTI 66
Query: 78 LPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC--LDRPIYPCRWLCEA 135
LPNLL H + + + PL+ C + FLCS++APVC LD+ I PCR LCE
Sbjct: 67 LPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCER 126
Query: 136 VRDSCEPVMQFFGFYWPEMLKCDKFP---EGDVCI 167
R CE +M FGF WPE L+C+ FP G++C+
Sbjct: 127 ARQGCEALMNKFGFQWPERLRCENFPVHGAGEICV 161
>gi|4503825 frizzled 1 [Homo sapiens]
Length = 647
Score = 103 bits (257), Expect = 2e-22
Identities = 48/127 (37%), Positives = 71/127 (55%), Gaps = 5/127 (3%)
Query: 46 YQSGRFYTKPPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNC 105
Y R + P P + LC ++ Y + ++PNLL H + + + PL+ C
Sbjct: 102 YNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQC 161
Query: 106 HAGTQVFLCSLFAPVC--LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP-- 161
A + FLCS++APVC L++ + PCR LCE R CE +M FGF WP+ LKC+KFP
Sbjct: 162 SAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVH 221
Query: 162 -EGDVCI 167
G++C+
Sbjct: 222 GAGELCV 228
>gi|22547161 frizzled 4 [Homo sapiens]
Length = 537
Score = 102 bits (254), Expect = 4e-22
Identities = 49/133 (36%), Positives = 73/133 (54%), Gaps = 9/133 (6%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P + +C N+GY +PNL+ HE + + Q +++ PL+ C + Q FLCS++ P+C
Sbjct: 47 PIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMC 106
Query: 122 LDR---PIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP----EGDVCIAMTPPNA 174
++ PI PC +C +V+ CEPV++ FGF WPE L C KFP +C M P
Sbjct: 107 TEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMC--MEGPGD 164
Query: 175 TEASKPQGTTVCP 187
E P T + P
Sbjct: 165 EEVPLPHKTPIQP 177
>gi|4503827 frizzled 2 [Homo sapiens]
Length = 565
Score = 101 bits (251), Expect = 1e-21
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P + LC ++ Y + ++PNLL H + + + PL+ C + FLCS++APVC
Sbjct: 41 PISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVC 100
Query: 122 --LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASK 179
L++ I PCR +CE R CE +M FGF WPE L+C+ FP N +E
Sbjct: 101 TVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGA 160
Query: 180 PQGTTVCPP 188
P T PP
Sbjct: 161 PALLTTAPP 169
>gi|6005762 frizzled 10 [Homo sapiens]
Length = 581
Score = 101 bits (251), Expect = 1e-21
Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P ++ +C ++GY +PNL+ HE E Q + PL+ CH + FLCSL+AP+C
Sbjct: 36 PIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMC 95
Query: 122 LDR---PIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGD--VCIAMTPPNATE 176
++ PI CR +CE R C P+M+ F F WP+ L C K P + + M PN
Sbjct: 96 TEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNGS 155
Query: 177 ASKPQGTTVCPPCDNELKSEAIIEH 201
+G+ + PP + + EH
Sbjct: 156 DEPTRGSGLFPPLFRPQRPHSAQEH 180
>gi|4503835 frizzled 9 [Homo sapiens]
Length = 591
Score = 97.8 bits (242), Expect = 1e-20
Identities = 62/181 (34%), Positives = 85/181 (46%), Gaps = 28/181 (15%)
Query: 11 RGAAL-GVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRLCH 69
RGA L LLA G A L +G + GR P Q V+IP +C
Sbjct: 7 RGALLLWQLLAAGGAALEIGRFDP-------------ERGRG-AAPCQAVEIP----MCR 48
Query: 70 NVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDR---PI 126
+GY +PNLL H + E + + + PL+ CH+ + FLCSL+AP+C D+ PI
Sbjct: 49 GIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPI 108
Query: 127 YPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVC 186
CR +CE R C P+M+ F F WP+ L C + P P+A P+ T
Sbjct: 109 PACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP------TRNDPHALCMEAPENATAG 162
Query: 187 P 187
P
Sbjct: 163 P 163
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 93.2 bits (230), Expect = 3e-19
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 7/133 (5%)
Query: 67 LCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLD--- 123
LC +GY +PN H+T E + + PL+ C + FLCS++ P+CL+
Sbjct: 42 LCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYK 101
Query: 124 RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPE----GDVCIAMTPPNATEASK 179
+P+ PCR +CE + C P+M+ +GF WP+ ++CD+ PE +C+ + T A+
Sbjct: 102 KPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAP 161
Query: 180 PQGTTVCPPCDNE 192
+ PP E
Sbjct: 162 SPPRRLPPPPPGE 174
>gi|27894385 frizzled 5 precursor [Homo sapiens]
Length = 585
Score = 91.7 bits (226), Expect = 8e-19
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 5/112 (4%)
Query: 53 TKPPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVF 112
+K P C +I + C +GY +PN H+T E + + PL+ C + F
Sbjct: 28 SKAPVCQEITVPM--CRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFF 85
Query: 113 LCSLFAPVCLD---RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP 161
LCS++ P+CL +P+ PCR +CE + C P+M+ +GF WPE + CD+ P
Sbjct: 86 LCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLP 137
>gi|38455388 frizzled-related protein [Homo sapiens]
Length = 325
Score = 90.5 bits (223), Expect = 2e-18
Identities = 68/263 (25%), Positives = 120/263 (45%), Gaps = 25/263 (9%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P + LC ++ + +PN L H T A + LL +C FLC+++AP+C
Sbjct: 37 PVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPIC 96
Query: 122 L----DRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGD--VCI---AMTPP 172
PI PC+ +CE R CEP++ + WPE L C++ P D VCI A+
Sbjct: 97 TIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPEAIVTA 156
Query: 173 NATEASKPQGTTVCPPCDNE------LKSEAIIEHLCASEFALRMKIKEVKKENGDKKIV 226
+ + C +E +++ + +R K+KE+K + D V
Sbjct: 157 DGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKTKCHDVTAV 216
Query: 227 PKKKKPLKLGPIKKKDLKKLVLYLKNGADCPCHQLDNLSHHFLIMG--RKVKSQYLL--- 281
+ K+ LK + ++ + + L + C C L N++ ++IMG + +S+ LL
Sbjct: 217 VEVKEILKSSLV---NIPRDTVNLYTSSGCLCPPL-NVNEEYIIMGYEDEERSRLLLVEG 272
Query: 282 TAIHKW-DKKNKEFKNFMKKMKN 303
+ KW D+ K+ K + K+++
Sbjct: 273 SIAEKWKDRLGKKVKRWDMKLRH 295
>gi|170784838 secreted frizzled-related protein 4 [Homo sapiens]
Length = 346
Score = 87.8 bits (216), Expect = 1e-17
Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 13/169 (7%)
Query: 55 PPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLC 114
P + V IP +C ++ + +PN L H T + L++ NC A + FLC
Sbjct: 23 PCEAVRIP----MCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLC 78
Query: 115 SLFAPVC----LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGD--VCIA 168
+++AP+C L PI PC+ +C+ RD CEP+M+ + WPE L CD+ P D VCI+
Sbjct: 79 AMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCIS 138
Query: 169 MTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVK 217
P A P+ + + E ++ C R K K+VK
Sbjct: 139 ---PEAIVTDLPEDVKWIDITPDMMVQERPLDVDCKRLSPDRCKCKKVK 184
>gi|8393378 frizzled 3 [Homo sapiens]
Length = 666
Score = 86.7 bits (213), Expect = 3e-17
Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P LR+C ++ Y +PNLL H + P++N +C + FLC+L+AP+C
Sbjct: 30 PITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPIC 89
Query: 122 LD--RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGD 164
++ R PCR LC+ C +M+ FG WPE ++C +FP+ D
Sbjct: 90 MEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCD 134
>gi|34734079 frizzled 6 [Homo sapiens]
Length = 706
Score = 80.9 bits (198), Expect = 1e-15
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVC 121
P + C + Y PNL+ H + + ++PL N C + FLC F P C
Sbjct: 26 PITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTC 85
Query: 122 LDR--PIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASK 179
+++ + PCR LCE V C+ ++ FG WPE L+CD+ D + +T TE
Sbjct: 86 IEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLG 145
Query: 180 PQGTT 184
PQ T
Sbjct: 146 PQKKT 150
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 72.8 bits (177), Expect = 4e-13
Identities = 41/126 (32%), Positives = 55/126 (43%), Gaps = 7/126 (5%)
Query: 62 PADLRLCHNVGYKKMVLPNLLEHETMAE--VKQQASSWVPLLNKNCHAGTQVFLCSLFAP 119
P L LC N+ Y PN H T E + ++S + L+ NC+ F C++ P
Sbjct: 457 PITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVP 516
Query: 120 VC---LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPE--GDVCIAMTPPNA 174
C I PCR LCE ++ CE V+ G WPE C +FPE D + P
Sbjct: 517 KCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCLMPDEY 576
Query: 175 TEASKP 180
E P
Sbjct: 577 VEECSP 582
Score = 52.4 bits (124), Expect = 5e-07
Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 19/154 (12%)
Query: 68 CHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCL----- 122
C + Y + P L M E+++ + L +C+ +F C+L P C+
Sbjct: 147 CQMLPYHATLTPLLSVVRNM-EMEKFLKFFTYLHRLSCYQHIMLFGCTLAFPECIIDGDD 205
Query: 123 DRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQG 182
+ PCR CEA ++ CE V+ + WP+ L+C +F N TE+S
Sbjct: 206 SHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQF-----------RNQTESSNVSR 254
Query: 183 TTVCPPCDN--ELKSEAIIEHLCASEFALRMKIK 214
P +N +L LCAS + K++
Sbjct: 255 ICFSPQQENGKQLLCGRGENFLCASGICIPGKLQ 288
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 63.5 bits (153), Expect = 2e-10
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 10/110 (9%)
Query: 58 CVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWV------PLLNKNCHAGTQV 111
CVD+ LR C + Y PNLL+H + EV + +S ++ LL C+ ++
Sbjct: 32 CVDL--QLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRL 88
Query: 112 FLCSLFAPVCLDRPIY-PCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKF 160
C++ AP C + PCR +CE +R+ C+P WP L C ++
Sbjct: 89 LGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 138
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 63.5 bits (153), Expect = 2e-10
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 10/110 (9%)
Query: 58 CVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWV------PLLNKNCHAGTQV 111
CVD+ LR C + Y PNLL+H + EV + +S ++ LL C+ ++
Sbjct: 43 CVDL--QLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRL 99
Query: 112 FLCSLFAPVCLDRPIY-PCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKF 160
C++ AP C + PCR +CE +R+ C+P WP L C ++
Sbjct: 100 LGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Query: 57 QCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSL 116
+C+ +P L +C ++G + LPN L HE+ +V+ A +W LL +CH F C L
Sbjct: 333 RCLPLPPSLPVCGHLGISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLL 392
Query: 117 FAPVCLDRP---IYPCRWLCEAVRDSC 140
P C P PC CEA++D+C
Sbjct: 393 LVPPCGSVPPPAPPPCCQFCEALQDAC 419
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 5/111 (4%)
Query: 55 PPQCVDIPADLRLCHNVGYKKMVLPNL-LEHETMAEVKQQASSWVPLLNKNCHAGTQVFL 113
PP+ P + +C + Y PN+ + T EV + S + L + C+ + L
Sbjct: 461 PPELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTSLPCYQHFRRLL 520
Query: 114 CSLFAPVC--LDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPE 162
C L P C L + PCR +C+ C+ + G WP C++ PE
Sbjct: 521 CGLLVPRCTPLGSVLPPCRSVCQEAEHQCQSGLALLGTPWP--FNCNRLPE 569
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 48.5 bits (114), Expect = 8e-06
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 6/85 (7%)
Query: 83 EHETMAEVKQQASSWVPLLNK-NCHAGTQVFLCSLFAPVCL-DRPIYPCRWLCEAVRDSC 140
+ ++ E + W L N C A Q LC+++ P C DR P R LC+A R C
Sbjct: 95 DSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPC 154
Query: 141 EPVMQFFGFYWPEMLKC--DKFPEG 163
V + G WP+ L+C D+FPEG
Sbjct: 155 AIVERERG--WPDFLRCTPDRFPEG 177
>gi|7662020 hypothetical protein LOC9766 [Homo sapiens]
Length = 303
Score = 35.0 bits (79), Expect = 0.086
Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 148 GFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPP--CDNELKSEAIIEHLCAS 205
G + P ++ C +G + PP G +C P C + L + ++IE+LCA
Sbjct: 22 GVFLPLVILCTLLGDGLASVCPLPPEPEN-----GGYICHPRPCRDPLTAGSVIEYLCAE 76
Query: 206 EFALRMKIKEVKKENGDKK 224
+ L+ K + +NG+ K
Sbjct: 77 GYMLKGDYKYLTCKNGEWK 95
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 33.5 bits (75), Expect = 0.25
Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 165 VCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKK 224
+C+ T T A + TT C EL I+ L SE ++ KEV +NGDKK
Sbjct: 595 ICLPCTE-GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKK 653
Query: 225 IVPKKKKPLKLGPIKKKDLKKLV 247
++ G K KD+ ++V
Sbjct: 654 GSCERDAQYAPGYDKVKDISEVV 676
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 33.5 bits (75), Expect = 0.25
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 152 PEM-LKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALR 210
PE+ L CD G + PP P G CPPC ++L E + E L + AL+
Sbjct: 903 PELILLCDSCDSGYHTACLRPPLMII---PDGEWFCPPCQHKLLCEKLEEQLQDLDVALK 959
Query: 211 MKIK-EVKKEN------GDKKIVPKKKKPLKLG-PIKKKDLKK 245
K + E +KE + I+P ++ KKKD KK
Sbjct: 960 KKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKK 1002
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 32.0 bits (71), Expect = 0.73
Identities = 17/59 (28%), Positives = 29/59 (49%)
Query: 188 PCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKDLKKL 246
P D + + ++ L + KE+ E +K I K+KP K IK+KD++K+
Sbjct: 755 PTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKM 813
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 32.0 bits (71), Expect = 0.73
Identities = 17/59 (28%), Positives = 29/59 (49%)
Query: 188 PCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKDLKKL 246
P D + + ++ L + KE+ E +K I K+KP K IK+KD++K+
Sbjct: 778 PTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKM 836
>gi|73695473 roquin [Homo sapiens]
Length = 1133
Score = 31.6 bits (70), Expect = 0.96
Identities = 11/15 (73%), Positives = 12/15 (80%)
Query: 45 PYQSGRFYTKPPQCV 59
PYQ G +YT PPQCV
Sbjct: 607 PYQQGMYYTPPPQCV 621
>gi|149408135 ret finger protein-like 3 isoform 1 [Homo sapiens]
Length = 317
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 160 FPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHL---CASEFALRMKIKEV 216
F E C + S G TVC C N L+ E E L C S + R KI+
Sbjct: 34 FQEASSCPVCSDYLEKPMSLECGCTVCLKCINSLQKEPHGEDLLCCCCSMVSQRNKIRPN 93
Query: 217 KK----ENGDKKIVPKKKKPLKLGPIKKK 241
++ + K++ PK KK L++ P +K
Sbjct: 94 RQLERLVSHIKELEPKLKKILQMNPRMRK 122
>gi|5730013 ret finger protein-like 3 isoform 2 [Homo sapiens]
Length = 288
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 160 FPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHL---CASEFALRMKIKEV 216
F E C + S G TVC C N L+ E E L C S + R KI+
Sbjct: 5 FQEASSCPVCSDYLEKPMSLECGCTVCLKCINSLQKEPHGEDLLCCCCSMVSQRNKIRPN 64
Query: 217 KK----ENGDKKIVPKKKKPLKLGPIKKK 241
++ + K++ PK KK L++ P +K
Sbjct: 65 RQLERLVSHIKELEPKLKKILQMNPRMRK 93
>gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens]
Length = 4857
Score = 30.4 bits (67), Expect = 2.1
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 78 LPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDRPIYPCRWLCEAVR 137
LP L HE V Q+ ++ ++ CHA +F+C + A + P LCE V
Sbjct: 2319 LPFTLAHERCISVVQKLVLFLLSMDFTCHADLLLFVCKVLARIA--NATRPTIHLCEIVN 2376
Query: 138 D 138
+
Sbjct: 2377 E 2377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,247,450
Number of Sequences: 37866
Number of extensions: 631863
Number of successful extensions: 1893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1829
Number of HSP's gapped (non-prelim): 61
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.