Guide to the Human Genome
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Search of human proteins with 56090582

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56090582 immunity-related GTPase family, Q [Homo sapiens]
         (623 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56090582 immunity-related GTPase family, Q [Homo sapiens]         1241   0.0  
gi|10257429 immunity-related GTPase family, cinema [Homo sapiens]      98   2e-20
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    46   9e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    43   8e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    42   0.001
gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|239752280 PREDICTED: similar to family with sequence similari...    40   0.008
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|210032463 family with sequence similarity 48, member B2 [Homo...    40   0.008
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             40   0.008
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             40   0.008
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]              39   0.014
gi|126352608 elastin isoform e precursor [Homo sapiens]                39   0.014
gi|126352322 elastin isoform c precursor [Homo sapiens]                39   0.014
gi|126352700 elastin isoform b precursor [Homo sapiens]                39   0.014
gi|121582655 ankyrin repeat domain 35 [Homo sapiens]                   39   0.014
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             39   0.019
gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]            38   0.024
gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo ...    38   0.024
gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo ...    38   0.024
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re...    38   0.024
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  38   0.032
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    37   0.042
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    37   0.042
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    37   0.042
gi|116292174 fidgetin-like 2 [Homo sapiens]                            37   0.042
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          37   0.042
gi|61966919 hypothetical protein LOC442444 [Homo sapiens]              37   0.042

>gi|56090582 immunity-related GTPase family, Q [Homo sapiens]
          Length = 623

 Score = 1241 bits (3211), Expect = 0.0
 Identities = 623/623 (100%), Positives = 623/623 (100%)

Query: 1   MPPPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGE 60
           MPPPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGE
Sbjct: 1   MPPPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGE 60

Query: 61  LSCPPAAPGPWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNLRPGD 120
           LSCPPAAPGPWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNLRPGD
Sbjct: 61  LSCPPAAPGPWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNLRPGD 120

Query: 121 SQTAAQARDQTAALLNSAGLGAADLFVLPANCGSSDGCEELERLRAALQSQAEALRRLLP 180
           SQTAAQARDQTAALLNSAGLGAADLFVLPANCGSSDGCEELERLRAALQSQAEALRRLLP
Sbjct: 121 SQTAAQARDQTAALLNSAGLGAADLFVLPANCGSSDGCEELERLRAALQSQAEALRRLLP 180

Query: 181 PAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVD 240
           PAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVD
Sbjct: 181 PAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVD 240

Query: 241 MLLGLDPGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDAL 300
           MLLGLDPGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDAL
Sbjct: 241 MLLGLDPGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDAL 300

Query: 301 ILVTPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGG 360
           ILVTPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGG
Sbjct: 301 ILVTPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGG 360

Query: 361 GLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDET 420
           GLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDET
Sbjct: 361 GLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDET 420

Query: 421 WEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAG 480
           WEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAG
Sbjct: 421 WEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAG 480

Query: 481 AWRPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGE 540
           AWRPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGE
Sbjct: 481 AWRPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGE 540

Query: 541 LAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGV 600
           LAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGV
Sbjct: 541 LAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGV 600

Query: 601 LLQALDEMRADAEAVLAPPEPAQ 623
           LLQALDEMRADAEAVLAPPEPAQ
Sbjct: 601 LLQALDEMRADAEAVLAPPEPAQ 623


>gi|10257429 immunity-related GTPase family, cinema [Homo sapiens]
          Length = 463

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 115/446 (25%), Positives = 180/446 (40%), Gaps = 62/446 (13%)

Query: 178 LLPPAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVG- 236
           ++P  ++   ++    LEA+R AFE+G L  A S ++  L    S RL++ V G++  G 
Sbjct: 8   VVPGEEENTILMAKERLEALRTAFESGDLPQAASHLQELLASTESIRLEVGVTGESGAGK 67

Query: 237 -LVVDMLLGLDPGDPGAAPASV---PTAPTPFPAPERPNVVLWTVP-LGHTG-TATTAAA 290
             +++ L GL+  DPGAA   V      P+P+P P+ P+V LW +P  G  G  A     
Sbjct: 68  SSLINALRGLEAEDPGAALTGVMETTMQPSPYPHPQFPDVTLWDLPGAGSPGCPADKYLK 127

Query: 291 ASHPTHYDALILVTPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPK 350
               + YD  +LV+P      +      +L        VRT  +    E L   + + P 
Sbjct: 128 QVDFSRYDFFLLVSPRRCGAVETRLAAEILCQGKKFYFVRTKVD----EDLAATRTQRPS 183

Query: 351 GESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSER 410
           G   + A        L + R+ C+   ++AG                             
Sbjct: 184 G--FREAA------VLQEIRDHCAERLREAGVA--------------------------- 208

Query: 411 AAALSPEDETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAA 470
                  D    ++    P  +       P L       LP  +  A LL+LP  S  A 
Sbjct: 209 -------DPRIFLVSNLSPARY-----DFPTLVSTWEHDLPSHRRHAGLLSLPDISLEAL 256

Query: 471 RTKAAALRAGAWRPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARR 530
           + K A L+    + AL+  +   A P+PGL  A D ALL   L  + R  GL+  +LA+ 
Sbjct: 257 QKKKAMLQEQVLKTALVLGV-IQALPVPGLAAAYDDALLIHSLRGYHRSFGLDDDSLAKL 315

Query: 531 ERALGLASGELAARAHFP-GPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAAT 589
              +G  +G+L +    P       E   RL + + +G    A   A     P  G    
Sbjct: 316 AEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVAR--AFERGIPVFGTLVA 373

Query: 590 GGLGYRAAHGVLLQALDEMRADAEAV 615
           GG+ + A + +L   L+EM  DA+ V
Sbjct: 374 GGISFGAVYTMLQGCLNEMAEDAQRV 399


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 48/155 (30%), Positives = 60/155 (38%), Gaps = 24/155 (15%)

Query: 349 PKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDS 408
           P+   ++ A  G L N +  G    +AG+  A   EG   A  E      G  + GGG  
Sbjct: 45  PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPE--PPPAGRARPGGGGP 102

Query: 409 ERAAALSPEDETWEVLEEAPPPVFPLRPG--GLPGLCEWLRRALPPAQAGALLLALPPAS 466
           +R    SP      V     PP   LRP   G  G C        P  A A + A P  +
Sbjct: 103 QRPGPPSPRRPL--VPAGPAPPAAKLRPPPEGSAGSCA-------PVPAAAAVAAGPEPA 153

Query: 467 PSAARTKAAALRAGAWRPALLASLAAAAAPLPGLG 501
           P           AG  +PA  A+LAA A P PG G
Sbjct: 154 P-----------AGPAKPAGPAALAARAGPGPGPG 177



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 75/331 (22%), Positives = 102/331 (30%), Gaps = 58/331 (17%)

Query: 204 GGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVDMLLGLDPGDPGAAPASVPTAPTP 263
           G LE+ L+   +    L     ++  A    +G  V  + G   G  GA PA+ P    P
Sbjct: 27  GSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHV--VSGSPAGAAGAGPAA-PAEGAP 83

Query: 264 FPAPERPNVVLWTVPLGHTGTATTAAAA-SHPTHYDALILVTPGAPTEKDWAQVQALLLP 322
             APE P       P G              P+    L+   P  P  K     +     
Sbjct: 84  GAAPEPP-------PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS 136

Query: 323 DAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGS 382
            AP+        G +P   G  K   P   + +   G G                   G 
Sbjct: 137 CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG--------------PGPGPGP 182

Query: 383 GEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGL 442
           G GPGK    G  Q +    +   +S  AAA +       ++   P  + PL     PG 
Sbjct: 183 GPGPGKPAGPGAAQTLN-GSAALLNSHHAAAPAVS-----LVNNGPAALLPLPKPAAPGT 236

Query: 443 C----EWLRRALPPAQAGA----------------------LLLALPPASPSAARTKAAA 476
                 ++  A PPA A                          LA PP  P+   T A A
Sbjct: 237 VIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296

Query: 477 LRAGAWRPALLASLAAAAAPLPGLGWACDVA 507
           +   A       S  AA AP P  G    V+
Sbjct: 297 VPPPA-AAQNGGSAGAAPAPAPAAGGPAGVS 326



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 53/211 (25%), Positives = 68/211 (32%), Gaps = 42/211 (19%)

Query: 252 AAPA-----SVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPG 306
           AAPA     + P A  P P P  P  V+ T P          AA S P          P 
Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA------APAPA 264

Query: 307 APTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENAL 366
           AP             P AP    R  G    P          P   + +N G  G   A 
Sbjct: 265 APAAAPPPP------PPAPATLARPPGHPAGPPTAAPAV---PPPAAAQNGGSAGAAPAP 315

Query: 367 SKGREKCSAGSQKAGSGE-GPGKAG--------SEGLQQVV--------GMKKSGGGDSE 409
           +      +AG     SG+ GPG A         +E  ++VV         +  SG   + 
Sbjct: 316 AP-----AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370

Query: 410 RAAALSPEDETWEVLEEAPPPVFPLRPGGLP 440
            +  + P  +       A PP  P  P GLP
Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 42/139 (30%), Positives = 47/139 (33%), Gaps = 15/139 (10%)

Query: 14  GPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPS----------LRAAGPGLFLGELSC 63
           G  G G +A          E   A   RP  G P           L  AGP     +L  
Sbjct: 69  GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128

Query: 64  PPAAPGPWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAV-RNLRPGDSQ 122
           PP       A       V  GPE      A   G AALAA A   P         PG  +
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188

Query: 123 T----AAQARDQTAALLNS 137
                AAQ  + +AALLNS
Sbjct: 189 PAGPGAAQTLNGSAALLNS 207


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
           +GEGE+ E  GEG+ E  +GE  +  G G  E    +G E+   G  +    EG G+   
Sbjct: 832 EGEGEEEE--GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889

Query: 392 EGLQQVVGMKKSGGGDSERAAALSPEDETWE 422
           EG  +  G ++ G G+ E       E+E  E
Sbjct: 890 EG--EGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 8/99 (8%)

Query: 332  DGEGEDPECLGEGKMENP----KGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPG 387
            +GEGE  E  GEGK E      +GE  +  G G  E+   +G E+      +   GEG G
Sbjct: 907  EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966

Query: 388  KAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEE 426
            +   EG     G +  G G+ E       E+E  E  EE
Sbjct: 967  EEEGEG----EGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 332  DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSA---GSQKAGSGEGPGK 388
            +GEGE  E  GEG+ E  +GE      G G E    +G E+      G  +   GEG G+
Sbjct: 976  EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035

Query: 389  AGSEGLQQVVGMKKSGGGDSERAAALSPEDE 419
               EG ++    +K G G+  R      E+E
Sbjct: 1036 E-EEGEEEGEEREKEGEGEENRRNREEEEEE 1065



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPG-KAG 390
           +GE E  E  GEG+ E  +GE  +   G G E       E+   G  +   GEG G + G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925

Query: 391 SEGLQQVVGMKKSGGGDSERAAALSPEDE-TWEVLEE 426
            EG  +  G ++ G G+ E       E+E  WE  EE
Sbjct: 926 EEG--EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960



 Score = 36.2 bits (82), Expect = 0.093
 Identities = 27/95 (28%), Positives = 39/95 (41%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
           +G+GE  E   EG+ E  +GE  +  G G  E    KG E+   G  +    EG G+   
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880

Query: 392 EGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEE 426
           E  +     +  G G+ E       E+   E  EE
Sbjct: 881 EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 332  DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
            +GEGE  E  GEG+ E  +GE  +  G G  E    +G E+     +    GEG G+   
Sbjct: 961  EGEGEGEE-EGEGEGEEGEGEGEEEEGEG--EGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017

Query: 392  EG--LQQVVGMKKSGGGDSERAAALSPEDE 419
            EG    +V G +  G G+ E       E E
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 3/88 (3%)

Query: 335 GEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGL 394
           GE  E  GE + E  +GE  +  G G  E    +  E    G ++   GEG  + G EG 
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE-EEGEEG- 874

Query: 395 QQVVGMKKSGGGDSERAAALSPEDETWE 422
            +  G ++ G G+ E       E+E  E
Sbjct: 875 -EGEGEEEEGEGEGEEEGEGEGEEEEGE 901



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 334  EGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEG 393
            EGE+ E  GEG+ E  +GE  +  G G  E    +G E+     +    GEG  +   EG
Sbjct: 956  EGEEEEGEGEGEEEG-EGEGEEGEGEGEEEEGEGEGEEE-EGEEEGEEEGEGEEEGEGEG 1013

Query: 394  LQQVVGMKKSGGGDSERAAALSPEDETWEVLEE 426
             ++  G +  G  + E       E+E  E  EE
Sbjct: 1014 EEEEEG-EVEGEVEGEEGEGEGEEEEGEEEGEE 1045



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 10/100 (10%)

Query: 330 RTDGEGEDPECL-----GEGKMEN-----PKGESLKNAGGGGLENALSKGREKCSAGSQK 379
           + +GEGE+ E       GE K E       KGE   + G G  E    +G EK   G  +
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE 815

Query: 380 AGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDE 419
            G  E       E  ++  G ++ G G+ E       E E
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 336 EDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQ 395
           E+ E  GEGK E  +GE ++    G  E    + +++  AG ++ G  EG    G E   
Sbjct: 747 EEEEKEGEGKEEG-EGEEVE----GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801

Query: 396 QVVGMKKSGGGDSERAAALSPEDETWEVLEE 426
           +  G +K  GG+ E       + E  E  EE
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 14/98 (14%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENAL---SKGREKCSAGSQKAGSGEGPGK 388
           +GEG++     EG+ E  +GE  K  G    E       KG E+   G  +    EG G+
Sbjct: 752 EGEGKE-----EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806

Query: 389 AGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEE 426
              EG +   G  + G G+ E       E+E  E  EE
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREE------EEEEGEGEEE 838


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 94/366 (25%), Positives = 127/366 (34%), Gaps = 67/366 (18%)

Query: 245  LDPGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALIL-V 303
            L PG P   P   P   TP P P  P  V    P       T  + AS  T YD+ +  +
Sbjct: 1584 LTPGPPHPLP-DTPAPATPLP-PVPPPAVAAAPP-------TLDSTASSLTSYDSEVATL 1634

Query: 304  TPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLE 363
            T GA              P AP       G    P     G     +    +++    LE
Sbjct: 1635 TQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPP-----GTDSGIEEVDSRSSSDHPLE 1689

Query: 364  NALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPE--DETW 421
                      SA +  + S EG G AG             GGG +    A  PE  D   
Sbjct: 1690 TI-------SSASTLSSLSAEGGGSAG-------------GGGGAGAGVASGPELLDTYV 1729

Query: 422  EVLE-------EAPPPVFP---LRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAAR 471
              L+         P P +P   + P  L G        L P  +G L   + P SP+ + 
Sbjct: 1730 AYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSV 1789

Query: 472  TKAA-----ALRAGAWRP-ALLASLAAAAAP-LPGLGWACDVALLRGQLAEWRRGLGLEP 524
            T A      ALRA +  P A +A    A  P +P +      +L R +L  W  G G  P
Sbjct: 1790 TGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPR-KLLPWEEGPGPPP 1848

Query: 525  TALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAG 584
              L        LA  + +A A     +  +E+ ++L  + G   AGGA        W  G
Sbjct: 1849 PPLPG-----PLAQPQASALATVKASII-SELSSKLQQFGGSSAAGGA------LPWARG 1896

Query: 585  GAAATG 590
            G+   G
Sbjct: 1897 GSGGGG 1902



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 55/220 (25%), Positives = 72/220 (32%), Gaps = 36/220 (16%)

Query: 250  PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAPT 309
            P  APA  P  P+P P P          P   +G AT        + + A ++   GA  
Sbjct: 1198 PSPAPAMSPVPPSPSPVP---------TPASPSGPAT----LDFTSQFGAALV---GAAR 1241

Query: 310  EKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKG 369
             +   Q +A       L     D +G D   LG G    P+    K+   G         
Sbjct: 1242 REGGWQNEARRRSTLFLSTDAGDEDGGDGG-LGTGAAPGPRLRHSKSIDEGMFSAEPYLR 1300

Query: 370  REKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPP 429
             E   +G+   G G G    G             GGG S   + L P      +  +A  
Sbjct: 1301 LESAGSGAGYGGYGAGSRAYG------------GGGGSSAFTSFLPPRPLVHPLTGKALD 1348

Query: 430  PVFPLRPGGLPGLCEWLR-RALPPAQAGALLLALPPASPS 468
            P  PL      GL    R RAL  +  G      PP  PS
Sbjct: 1349 PASPL------GLALAARERALKESSEGGGAPQPPPRPPS 1382


>gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 70/255 (27%), Positives = 88/255 (34%), Gaps = 60/255 (23%)

Query: 373 CSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWE---------- 422
           C + + K GS  G     S  +   +G ++ G   + RA A +P                
Sbjct: 265 CRSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIAL 324

Query: 423 -------VLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAA 475
                  V    P  + P  PG L G   W+ RA+ P   GAL      A  +  RT  A
Sbjct: 325 TPGVLCGVRSRVPKDITPT-PGALRGYKSWVCRAIAPT-PGALRGDRSAARTAVVRTPGA 382

Query: 476 -------ALRAGAWRPALL----ASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEP 524
                  A  A A  P  L    +S++ A AP PG         LRG  +  R      P
Sbjct: 383 LGRDRSRARSAIASTPGTLQGNRSSVSKAIAPTPG--------ALRGDRSAARTAFVPTP 434

Query: 525 TALAR-RERA-----------LGLASGELAARAHFPGPV------TRAEVEARLGAWAG- 565
            AL R R RA            G  S    A A  PG +       R  +    GAW G 
Sbjct: 435 GALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGALRGYKSWARRAIAPNPGAWRGY 494

Query: 566 ---EGTAGGAALGAL 577
               GTA    LGAL
Sbjct: 495 RSTTGTAIAPNLGAL 509



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 54/188 (28%), Positives = 70/188 (37%), Gaps = 38/188 (20%)

Query: 436 PGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAGAWRPALL-------- 487
           PG L G   W RRA+ P           P + S+ R+++   R  A  PA L        
Sbjct: 524 PGALRGYRSWTRRAIAPT----------PGTLSSYRSRSR--RTIASTPATLRGEKSRAH 571

Query: 488 ASLAAAAAPLPGLGWACDVALL--RGQLAE-WRR-GLGLEPTALARR------ERALGLA 537
            SLA     L G G     A++     L E W R G+G+ P A A R       RA+   
Sbjct: 572 TSLAPTPGALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRSPVRRAIAPT 631

Query: 538 SGELA--------ARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAAT 589
            G L+        A A  PG +      +R    +   T  G    A + L PA GA   
Sbjct: 632 PGTLSGYRSRARTAIAPTPGTLRGYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRG 691

Query: 590 GGLGYRAA 597
            G   R A
Sbjct: 692 DGSRARRA 699


>gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 66/254 (25%), Positives = 87/254 (34%), Gaps = 58/254 (22%)

Query: 373 CSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWE---------- 422
           C + + K GS  G     S  +   +G ++ G   + RA A +P                
Sbjct: 265 CRSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIAL 324

Query: 423 -------VLEEAPPPVFPLRPGGLPGLCEWLRRALPP------AQAGALLLALPPASPSA 469
                  V    P  + P  PG L G   W+ RA+ P          A   A+     + 
Sbjct: 325 TPGVLCGVRSRVPKDITPT-PGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGAL 383

Query: 470 ARTKAAALRAGAWRPALL----ASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPT 525
            R ++ A  A A  P  L    +S++ A AP PG         LRG  +  R      P 
Sbjct: 384 GRDRSRARSAIASTPGTLQGNRSSVSKAIAPAPG--------ALRGDRSAARTAFVPTPG 435

Query: 526 ALAR-RERA-----------LGLASGELAARAHFPGPV------TRAEVEARLGAWAG-- 565
           AL R R RA            G  S    A A  PG +       R  +    GAW G  
Sbjct: 436 ALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGALRGYKSWARRAIAPNPGAWRGYR 495

Query: 566 --EGTAGGAALGAL 577
              GTA    LGAL
Sbjct: 496 STTGTAIAPNLGAL 509



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 54/188 (28%), Positives = 70/188 (37%), Gaps = 38/188 (20%)

Query: 436 PGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAGAWRPALL-------- 487
           PG L G   W RRA+ P           P + S+ R+++   R  A  PA L        
Sbjct: 524 PGALRGYRSWTRRAIAPT----------PGTLSSYRSRSR--RTIASTPATLRGEKSRAH 571

Query: 488 ASLAAAAAPLPGLGWACDVALL--RGQLAE-WRR-GLGLEPTALARR------ERALGLA 537
            SLA     L G G     A++     L E W R G+G+ P A A R       RA+   
Sbjct: 572 TSLAPTPGALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRSPVRRAIAPT 631

Query: 538 SGELA--------ARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAAT 589
            G L+        A A  PG +      +R    +   T  G    A + L PA GA   
Sbjct: 632 PGTLSGYRSRARTAIAPTPGTLRGYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRG 691

Query: 590 GGLGYRAA 597
            G   R A
Sbjct: 692 DGSRARRA 699


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 55/198 (27%), Positives = 79/198 (39%), Gaps = 24/198 (12%)

Query: 379 KAGSGEGPGKAGSEGLQQVVGMKKSGG--GDSERAAALSPEDETWEVLEEAPPPVF---- 432
           + GS    G+A S+  + V    K  G    S    A   +  +W+  E+ P PV+    
Sbjct: 356 RPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ-PDPVWVQSS 414

Query: 433 --------PLRPGGLPGLCEWLR--RALPPAQAGA-LLLALPPASPSAARTKAAALRAGA 481
                   P     LP     +    + PP QAG+ L    P A+P+ A    A   A A
Sbjct: 415 VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPA 474

Query: 482 WRPALLASLAAAAA--PLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASG 539
             PAL A+  AAAA    P       V L++   A  RR     PT   +   A+ + +G
Sbjct: 475 AAPALAAAAVAAAAGGAAPSHSQKPSVPLIK---ASRRRPAAGRPTRFVKIAPAIQVRTG 531

Query: 540 ELAARA-HFPGPVTRAEV 556
               +A +  GPV  A+V
Sbjct: 532 STGLKATNVEGPVRGAQV 549



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 7/86 (8%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAPT 309
           P AAPA    AP P PAP          P         AA  + P+H     +    A  
Sbjct: 456 PAAAPAVAAAAPAPAPAPA-------AAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASR 508

Query: 310 EKDWAQVQALLLPDAPLVCVRTDGEG 335
            +  A      +  AP + VRT   G
Sbjct: 509 RRPAAGRPTRFVKIAPAIQVRTGSTG 534


>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2028

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 66/254 (25%), Positives = 87/254 (34%), Gaps = 58/254 (22%)

Query: 373 CSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWE---------- 422
           C + + K GS  G     S  +   +G ++ G   + RA A +P                
Sbjct: 265 CRSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIAL 324

Query: 423 -------VLEEAPPPVFPLRPGGLPGLCEWLRRALPP------AQAGALLLALPPASPSA 469
                  V    P  + P  PG L G   W+ RA+ P          A   A+     + 
Sbjct: 325 TPGVLCGVRSRVPKDITPT-PGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGAL 383

Query: 470 ARTKAAALRAGAWRPALL----ASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPT 525
            R ++ A  A A  P  L    +S++ A AP PG         LRG  +  R      P 
Sbjct: 384 GRDRSRARSAIASTPGTLQGNRSSVSKAIAPAPG--------ALRGDRSAARTAFVPTPG 435

Query: 526 ALAR-RERA-----------LGLASGELAARAHFPGPV------TRAEVEARLGAWAG-- 565
           AL R R RA            G  S    A A  PG +       R  +    GAW G  
Sbjct: 436 ALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGALRGYKSWARRAIAPNPGAWRGYR 495

Query: 566 --EGTAGGAALGAL 577
              GTA    LGAL
Sbjct: 496 STTGTAIAPNLGAL 509



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 34/160 (21%)

Query: 436 PGGLPGLCEWLRRALPPA--------QAGALLLALPPASPSAARTKA---AALRAGAWRP 484
           PG L G   W RRA+ P               +A  PA+    +++A    A   GA R 
Sbjct: 524 PGALRGYRSWTRRAIAPTPGTLSSYRSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRD 583

Query: 485 AL---LASLAAAAAPLPG----------LGWACDVALLRGQLAEWRRGLGLEPTAL---- 527
           AL    + +  A AP PG             A     LRG     RR +   P  L    
Sbjct: 584 ALRRDRSPVRRAIAPTPGTLSGYRSRARTAIAPTPGTLRGYRPRSRRAIASTPATLRGEK 643

Query: 528 ARRERALGLASGEL------AARAHFPGPVTRAEVEARLG 561
           +R   +L  A G L      A RA  P      E+ +R+G
Sbjct: 644 SRAHTSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRVG 683


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 66/254 (25%), Positives = 87/254 (34%), Gaps = 58/254 (22%)

Query: 373 CSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWE---------- 422
           C + + K GS  G     S  +   +G ++ G   + RA A +P                
Sbjct: 265 CRSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIAL 324

Query: 423 -------VLEEAPPPVFPLRPGGLPGLCEWLRRALPP------AQAGALLLALPPASPSA 469
                  V    P  + P  PG L G   W+ RA+ P          A   A+     + 
Sbjct: 325 TPGVLCGVRSRVPKDITPT-PGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGAL 383

Query: 470 ARTKAAALRAGAWRPALL----ASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPT 525
            R ++ A  A A  P  L    +S++ A AP PG         LRG  +  R      P 
Sbjct: 384 GRDRSRARSAIASTPGTLQGNRSSVSKAIAPAPG--------ALRGDRSAARTAFVPTPG 435

Query: 526 ALAR-RERA-----------LGLASGELAARAHFPGPV------TRAEVEARLGAWAG-- 565
           AL R R RA            G  S    A A  PG +       R  +    GAW G  
Sbjct: 436 ALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGALRGYKSWARRAIAPNPGAWRGYR 495

Query: 566 --EGTAGGAALGAL 577
              GTA    LGAL
Sbjct: 496 STTGTAIAPNLGAL 509


>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 55/198 (27%), Positives = 79/198 (39%), Gaps = 24/198 (12%)

Query: 379 KAGSGEGPGKAGSEGLQQVVGMKKSGG--GDSERAAALSPEDETWEVLEEAPPPVF---- 432
           + GS    G+A S+  + V    K  G    S    A   +  +W+  E+ P PV+    
Sbjct: 394 RPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ-PDPVWVQSS 452

Query: 433 --------PLRPGGLPGLCEWLR--RALPPAQAGA-LLLALPPASPSAARTKAAALRAGA 481
                   P     LP     +    + PP QAG+ L    P A+P+ A    A   A A
Sbjct: 453 VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPA 512

Query: 482 WRPALLASLAAAAA--PLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASG 539
             PAL A+  AAAA    P       V L++   A  RR     PT   +   A+ + +G
Sbjct: 513 AAPALAAAAVAAAAGGAAPSHSQKPSVPLIK---ASRRRPAAGRPTRFVKIAPAIQVRTG 569

Query: 540 ELAARA-HFPGPVTRAEV 556
               +A +  GPV  A+V
Sbjct: 570 STGLKATNVEGPVRGAQV 587



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 7/86 (8%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAPT 309
           P AAPA    AP P PAP          P         AA  + P+H     +    A  
Sbjct: 494 PAAAPAVAAAAPAPAPAPA-------AAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASR 546

Query: 310 EKDWAQVQALLLPDAPLVCVRTDGEG 335
            +  A      +  AP + VRT   G
Sbjct: 547 RRPAAGRPTRFVKIAPAIQVRTGSTG 572


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
           D E ED      G  E    ESL  + GG    + S      S G+  + SG+G GK G 
Sbjct: 103 DEEEEDESSSSGGGEEESSAESLVGSSGG----SSSDETRSLSPGAASSSSGDGDGKEGL 158

Query: 392 EGLQQVVGMKKSGGGDSERAAALS 415
           E  +   G +  GGG S  ++ +S
Sbjct: 159 EEPKGPRGSQGGGGGGSSSSSVVS 182



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 342 GEGK--MENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVG 399
           G+GK  +E PKG      GGGG     S      S G +  G+G G   A S G +  + 
Sbjct: 152 GDGKEGLEEPKGPRGSQGGGGG---GSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLE 208

Query: 400 MKKSG 404
           M   G
Sbjct: 209 MSSDG 213


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 332 DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
           D E ED      G  E    ESL  + GG    + S      S G+  + SG+G GK G 
Sbjct: 103 DEEEEDESSSSGGGEEESSAESLVGSSGG----SSSDETRSLSPGAASSSSGDGDGKEGL 158

Query: 392 EGLQQVVGMKKSGGGDSERAAALS 415
           E  +   G +  GGG S  ++ +S
Sbjct: 159 EEPKGPRGSQGGGGGGSSSSSVVS 182



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 342 GEGK--MENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVG 399
           G+GK  +E PKG      GGGG     S      S G +  G+G G   A S G +  + 
Sbjct: 152 GDGKEGLEEPKGPRGSQGGGGG---GSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLE 208

Query: 400 MKKSG 404
           M   G
Sbjct: 209 MSSDG 213


>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
          Length = 832

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 31/75 (41%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 449 ALPPAQAGALLLALPPASPSAARTKAAALRAGAWRPALLASLAAAAAPLPGLGWACDVAL 508
           ALPP  A     ALPPA P  +   AAA  +GA  PA  A  AA  A  PG G +  +A+
Sbjct: 24  ALPPQPA-----ALPPAPPQGSPCAAAAGGSGACGPA-TAVAAAGTAEGPGGGGSARIAV 77

Query: 509 LRGQLAEWRRGLGLE 523
            + QL    R   LE
Sbjct: 78  KKAQLRSAPRAKKLE 92


>gi|126352608 elastin isoform e precursor [Homo sapiens]
          Length = 705

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 94/377 (24%), Positives = 124/377 (32%), Gaps = 53/377 (14%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAP- 308
           PG   A VP  P   P       +     +G    A  AAAA+    Y A   + PG P 
Sbjct: 275 PGVGGAGVPGVPGAIPG------IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 328

Query: 309 -----TEKDWAQVQALLLPDAPLVCVRTDG-------EGEDPECLGEGKMENPKGESLKN 356
                     A V  + +P A +  V   G           PE   +   +  K  +   
Sbjct: 329 FGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 388

Query: 357 AGGGGLENALSKGREKCSAGSQKAG-SGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALS 415
            G GG+           + G    G  G G G  G  G+  V G+    G        +S
Sbjct: 389 VGVGGIP----------TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 438

Query: 416 PEDETWEVLEEAPPPVFP---LRP--GGLPGLCEWLRRALPPAQAGALLLALPP---ASP 467
           PE +     + A   + P   + P  G  PG+       L P    A  + + P    +P
Sbjct: 439 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 498

Query: 468 SAARTKAAALRAGAWRPALLASLAAAA---APLPGLGWACDVALLRGQLAEWRRGLGLEP 524
                  AA    A + A  A L AAA   A +PGLG    V  L         G G+  
Sbjct: 499 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-------GVGAGVPG 551

Query: 525 TALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAG 584
             +       G   G LAA            V   LGA  G G  GG  +GA     PA 
Sbjct: 552 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG-VVGA----GPAA 606

Query: 585 GAAATGGLGYRAAHGVL 601
            AAA       A  G++
Sbjct: 607 AAAAAKAAAKAAQFGLV 623


>gi|126352322 elastin isoform c precursor [Homo sapiens]
          Length = 692

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 94/377 (24%), Positives = 124/377 (32%), Gaps = 53/377 (14%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAP- 308
           PG   A VP  P   P       +     +G    A  AAAA+    Y A   + PG P 
Sbjct: 280 PGVGGAGVPGVPGAIPG------IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 333

Query: 309 -----TEKDWAQVQALLLPDAPLVCVRTDG-------EGEDPECLGEGKMENPKGESLKN 356
                     A V  + +P A +  V   G           PE   +   +  K  +   
Sbjct: 334 FGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 393

Query: 357 AGGGGLENALSKGREKCSAGSQKAG-SGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALS 415
            G GG+           + G    G  G G G  G  G+  V G+    G        +S
Sbjct: 394 VGVGGIP----------TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443

Query: 416 PEDETWEVLEEAPPPVFP---LRP--GGLPGLCEWLRRALPPAQAGALLLALPP---ASP 467
           PE +     + A   + P   + P  G  PG+       L P    A  + + P    +P
Sbjct: 444 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 503

Query: 468 SAARTKAAALRAGAWRPALLASLAAAA---APLPGLGWACDVALLRGQLAEWRRGLGLEP 524
                  AA    A + A  A L AAA   A +PGLG    V  L         G G+  
Sbjct: 504 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-------GVGAGVPG 556

Query: 525 TALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAG 584
             +       G   G LAA            V   LGA  G G  GG  +GA     PA 
Sbjct: 557 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG-VVGA----GPAA 611

Query: 585 GAAATGGLGYRAAHGVL 601
            AAA       A  G++
Sbjct: 612 AAAAAKAAAKAAQFGLV 628


>gi|126352700 elastin isoform b precursor [Homo sapiens]
          Length = 677

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 94/377 (24%), Positives = 124/377 (32%), Gaps = 53/377 (14%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAP- 308
           PG   A VP  P   P       +     +G    A  AAAA+    Y A   + PG P 
Sbjct: 265 PGVGGAGVPGVPGAIPG------IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 318

Query: 309 -----TEKDWAQVQALLLPDAPLVCVRTDG-------EGEDPECLGEGKMENPKGESLKN 356
                     A V  + +P A +  V   G           PE   +   +  K  +   
Sbjct: 319 FGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 378

Query: 357 AGGGGLENALSKGREKCSAGSQKAG-SGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALS 415
            G GG+           + G    G  G G G  G  G+  V G+    G        +S
Sbjct: 379 VGVGGIP----------TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 428

Query: 416 PEDETWEVLEEAPPPVFP---LRP--GGLPGLCEWLRRALPPAQAGALLLALPP---ASP 467
           PE +     + A   + P   + P  G  PG+       L P    A  + + P    +P
Sbjct: 429 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 488

Query: 468 SAARTKAAALRAGAWRPALLASLAAAA---APLPGLGWACDVALLRGQLAEWRRGLGLEP 524
                  AA    A + A  A L AAA   A +PGLG    V  L         G G+  
Sbjct: 489 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-------GVGAGVPG 541

Query: 525 TALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAG 584
             +       G   G LAA            V   LGA  G G  GG  +GA     PA 
Sbjct: 542 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG-VVGA----GPAA 596

Query: 585 GAAATGGLGYRAAHGVL 601
            AAA       A  G++
Sbjct: 597 AAAAAKAAAKAAQFGLV 613


>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
          Length = 1001

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 18/198 (9%)

Query: 386 PGKAGSEGLQQVVGMKKSGGGDSERAAALSPED-ETWEVLEEAPPPVFPLRPGGLPGLCE 444
           P    SE +++  G + +  G    A    P+  +     ++    V  + PGG      
Sbjct: 428 PQSPASETIRKATGQQLTTNG----AQTFGPDHADQLPAGQKESSQVLGVEPGGT----- 478

Query: 445 WLRRALPPAQAGALLLALPPASPSAARTKAAALRAGAWRPALLASLAAAAAPLPGLGWAC 504
            +   + PA    LLL L     +  R K AA R    RP +  +L    A      W  
Sbjct: 479 -VAEPVGPAAMNQLLLQLREELAAVWREKDAA-RGALSRPVMEGALGTPRAEAAAAAWEK 536

Query: 505 DVALLRGQLA--EWRR-GLGLEPTALAR--RERALGLASGELAARAHFPGPVTRAEVEAR 559
             A L   LA  EW + GL ++P   ++  RE AL  A G +         V  A  E  
Sbjct: 537 MEARLERVLARLEWAKAGLQVKPEVPSQESREGALKAAPGSIKQDEEKEKRVPGARGEP- 595

Query: 560 LGAWAGEGTAGGAALGAL 577
           LGA  GE   GG A G L
Sbjct: 596 LGALGGEKALGGLAKGQL 613


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 53/184 (28%), Positives = 66/184 (35%), Gaps = 32/184 (17%)

Query: 336 EDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQ 395
           +D   LG G+   PKG     +GGGG                  AG+G G G  G+  L 
Sbjct: 365 KDDPVLGAGE---PKGGPGTGSGGGG------------------AGTGGGAGGPGASHLP 403

Query: 396 QVVGMKKSGG----GDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALP 451
              G    GG    G     AA   +D        A   V+P  P   P        + P
Sbjct: 404 PGAGAGPGGGAMFWGHQPSGAA---KDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYP 460

Query: 452 PAQAGALLLALPPASPSAARTKAAALRAGAWRPALLASLAAAAAPLPGLGWACDVALLRG 511
            AQ+ A  +A   A+ +AA    AA  AG+  P  L     A     G    C  AL RG
Sbjct: 461 AAQSQAKAVAAAVAAAAAA----AAAAAGSGAPEPLDGAEPAKESGLGAEERCPSALSRG 516

Query: 512 QLAE 515
            L E
Sbjct: 517 PLDE 520



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 68/279 (24%), Positives = 90/279 (32%), Gaps = 57/279 (20%)

Query: 376 GSQKAGSGEGP-------GKAGSEGLQQVVGMKKSGGGDSERAAALSP-EDETWEVLEEA 427
           G  +A    GP       G   + G     G    GGG   R+  + P   + + +L++ 
Sbjct: 285 GEDEAAGPPGPPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKL 344

Query: 428 PPPVFPLRPGGLP---GLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAGAWRP 484
           PPP+FP  P G P   GLC       P      L    P   P        A   G    
Sbjct: 345 PPPLFP-HPYGFPTAFGLC-------PKKDDPVLGAGEPKGGPGTGSGGGGAGTGGGAGG 396

Query: 485 ALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGELAAR 544
              + L   A   PG           G    W    G +P+  A+   A+  A+      
Sbjct: 397 PGASHLPPGAGAGPG-----------GGAMFW----GHQPSGAAKDAAAVAAAAAAATVY 441

Query: 545 AHFP-------------GPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGA--AAT 589
             FP              P  +++ +A   A A    A  AA G+     P  GA  A  
Sbjct: 442 PTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGS-GAPEPLDGAEPAKE 500

Query: 590 GGLG--YRAAHGVLLQALDEMRADAE-----AVLAPPEP 621
            GLG   R    +    LDE   D       A L PP P
Sbjct: 501 SGLGAEERCPSALSRGPLDEDGTDEALPPPLAPLPPPPP 539


>gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 513

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 12/149 (8%)

Query: 358 GGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPE 417
           G GG   AL++        ++   +G GP  A      Q++G+     G +  AA +  E
Sbjct: 161 GRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGV-----GSAGLAAVVGDE 215

Query: 418 DETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAAL 477
            +      + P  +   R GGLP     +         G   L    A P AA   A  L
Sbjct: 216 AQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGL 275

Query: 478 R-------AGAWRPALLASLAAAAAPLPG 499
           R       A A R  LLA+    A P PG
Sbjct: 276 RRRHRRPPAAAARRPLLAAARRGALPAPG 304


>gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo
           sapiens]
          Length = 513

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 12/149 (8%)

Query: 358 GGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPE 417
           G GG   AL++        ++   +G GP  A      Q++G+     G +  AA +  E
Sbjct: 161 GRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGV-----GSAGLAAVVGDE 215

Query: 418 DETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAAL 477
            +      + P  +   R GGLP     +         G   L    A P AA   A  L
Sbjct: 216 AQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGL 275

Query: 478 R-------AGAWRPALLASLAAAAAPLPG 499
           R       A A R  LLA+    A P PG
Sbjct: 276 RRRHRRPPAAAARRPLLAAARRGALPAPG 304


>gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo
           sapiens]
          Length = 513

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 12/149 (8%)

Query: 358 GGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPE 417
           G GG   AL++        ++   +G GP  A      Q++G+     G +  AA +  E
Sbjct: 161 GRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGV-----GSAGLAAVVGDE 215

Query: 418 DETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAAL 477
            +      + P  +   R GGLP     +         G   L    A P AA   A  L
Sbjct: 216 AQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGL 275

Query: 478 R-------AGAWRPALLASLAAAAAPLPG 499
           R       A A R  LLA+    A P PG
Sbjct: 276 RRRHRRPPAAAARRPLLAAARRGALPAPG 304


>gi|38569493 potassium voltage-gated channel, subfamily H
            (eag-related), member 3 [Homo sapiens]
          Length = 1083

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 14/131 (10%)

Query: 382  SGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPG 441
            SGEGP  A + GL Q + +         +  A S    TW      PPP+    P G P 
Sbjct: 922  SGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGSVLSGTWPHPRPGPPPLMAPWPWGPPA 981

Query: 442  L--CEWLRRAL---------PPAQAGALLLALPPASPSAARTKAAALRAGAWRPALLASL 490
                 W R            PPA      L   P++P++        R G   P   A  
Sbjct: 982  SQSSPWPRATAFWTSTSDSEPPASGD---LCSEPSTPASPPPSEEGARTGPAEPVSQAEA 1038

Query: 491  AAAAAPLPGLG 501
             +   P PG G
Sbjct: 1039 TSTGEPPPGSG 1049


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 71/257 (27%), Positives = 90/257 (35%), Gaps = 35/257 (13%)

Query: 250 PGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGT-ATTAAAASHPTHYDALILVTPGAP 308
           P A  A+   AP    A  R      TVP    G  A   AA   PT +  L ++ P   
Sbjct: 401 PRAPKAAAKAAPAKRTARRRXXXXD-TVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKF 459

Query: 309 TEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKN---AGGGGLENA 365
             +    V  LL P AP  C         P     G+   P+ E L+    AG GG+   
Sbjct: 460 NSRRRRCV--LLGPVAPAACAPCASAPCAPAPAASGRP--PRAEELERRALAGAGGVG-- 513

Query: 366 LSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALS--PEDETWEV 423
                   +AG++   +G+ P KAG        G    GGG S  A +    P+DE  + 
Sbjct: 514 --------AAGAEPPNAGD-PFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDE 564

Query: 424 LE----EAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRA 479
            E    EA       R GG           L    +G    A   ASP A   +AAA   
Sbjct: 565 DEAPETEAARGAEEARGGG---------GGLGARGSGCQGAAETDASPGATVDEAAAPGP 615

Query: 480 GAWRPALLASLAAAAAP 496
               P        AAAP
Sbjct: 616 RENSPVAPGPPGGAAAP 632



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 31/101 (30%), Positives = 40/101 (39%), Gaps = 2/101 (1%)

Query: 29  DKDVETLEAPEGRPDSGVPSLRAAGPGLFLGELSCPPAAPGPWAAEANVLVLVLPGPEGN 88
           D+D +  EAPE     G    R  G GL      C  AA    +  A V     PGP  N
Sbjct: 559 DEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPREN 618

Query: 89  GEPLAPA-LGEAALAALARGTPLLAVRNLRPGDSQTAAQAR 128
             P+AP   G AA    A  TP       +P   +T + ++
Sbjct: 619 -SPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSK 658



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 27/71 (38%), Positives = 29/71 (40%), Gaps = 3/71 (4%)

Query: 523 EPTALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWP 582
           E  A    E A G   G L AR    G    AE +A  GA   E  A G    +     P
Sbjct: 569 ETEAARGAEEARG-GGGGLGARGS--GCQGAAETDASPGATVDEAAAPGPRENSPVAPGP 625

Query: 583 AGGAAATGGLG 593
            GGAAA GG G
Sbjct: 626 PGGAAAPGGAG 636


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 53/204 (25%), Positives = 62/204 (30%), Gaps = 40/204 (19%)

Query: 247  PGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPG 306
            PG PG      P  P  FP P+ P       P G  G                     PG
Sbjct: 924  PGPPGERGPQGPQGPVGFPGPKGP-----PGPPGKDG--------------------LPG 958

Query: 307  APTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENAL 366
             P ++     Q    P  P   V   G   +   +GE     P G      G  GL  A 
Sbjct: 959  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP----PGEQGLPGAA 1014

Query: 367  SKGREKCSAGSQKAGSGEG-------PGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDE 419
             K   K   G Q     +G       PG+ G  G Q   G+K   G         SP + 
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 420  TWEVLEEAPPPVFPLRPG--GLPG 441
                   A P   P RPG  G PG
Sbjct: 1075 --GSAGTAGPIGLPGRPGPQGPPG 1096



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 332  DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
            DG+   P   G      P G   K    G    A ++GR+       +AG+   PGK G 
Sbjct: 1350 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGA---AGAEGRQGEKGAKGEAGAEGPPGKTGP 1406

Query: 392  EGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGL 442
             G Q   G K    G       +  +       ++ PP   P+ P GLPGL
Sbjct: 1407 VGPQGPAG-KPGPEGLRGIPGPVGEQGLPGAAGQDGPPG--PMGPPGLPGL 1454


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 53/204 (25%), Positives = 62/204 (30%), Gaps = 40/204 (19%)

Query: 247  PGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPG 306
            PG PG      P  P  FP P+ P       P G  G                     PG
Sbjct: 873  PGPPGERGPQGPQGPVGFPGPKGP-----PGPPGKDG--------------------LPG 907

Query: 307  APTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENAL 366
             P ++     Q    P  P   V   G   +   +GE     P G      G  GL  A 
Sbjct: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP----PGEQGLPGAA 963

Query: 367  SKGREKCSAGSQKAGSGEG-------PGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDE 419
             K   K   G Q     +G       PG+ G  G Q   G+K   G         SP + 
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 420  TWEVLEEAPPPVFPLRPG--GLPG 441
                   A P   P RPG  G PG
Sbjct: 1024 --GSAGTAGPIGLPGRPGPQGPPG 1045



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 332  DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
            DG+   P   G      P G   K    G    A ++GR+       +AG+   PGK G 
Sbjct: 1299 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGA---AGAEGRQGEKGAKGEAGAEGPPGKTGP 1355

Query: 392  EGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGL 442
             G Q   G K    G       +  +       ++ PP   P+ P GLPGL
Sbjct: 1356 VGPQGPAG-KPGPEGLRGIPGPVGEQGLPGAAGQDGPPG--PMGPPGLPGL 1403


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 53/204 (25%), Positives = 62/204 (30%), Gaps = 40/204 (19%)

Query: 247  PGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPG 306
            PG PG      P  P  FP P+ P       P G  G                     PG
Sbjct: 912  PGPPGERGPQGPQGPVGFPGPKGP-----PGPPGKDG--------------------LPG 946

Query: 307  APTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENAL 366
             P ++     Q    P  P   V   G   +   +GE     P G      G  GL  A 
Sbjct: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP----PGEQGLPGAA 1002

Query: 367  SKGREKCSAGSQKAGSGEG-------PGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDE 419
             K   K   G Q     +G       PG+ G  G Q   G+K   G         SP + 
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 420  TWEVLEEAPPPVFPLRPG--GLPG 441
                   A P   P RPG  G PG
Sbjct: 1063 --GSAGTAGPIGLPGRPGPQGPPG 1084



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 332  DGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGS 391
            DG+   P   G      P G   K    G    A ++GR+       +AG+   PGK G 
Sbjct: 1338 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGA---AGAEGRQGEKGAKGEAGAEGPPGKTGP 1394

Query: 392  EGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGL 442
             G Q   G K    G       +  +       ++ PP   P+ P GLPGL
Sbjct: 1395 VGPQGPAG-KPGPEGLRGIPGPVGEQGLPGAAGQDGPPG--PMGPPGLPGL 1442


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 79/300 (26%), Positives = 99/300 (33%), Gaps = 63/300 (21%)

Query: 244 GLDPGDPGAAPASVPT----APTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDA 299
           G  P  PG  PA   T    APTP PAP  P            G  T A  A        
Sbjct: 217 GALPPPPGPPPAPYLTPGLPAPTPLPAPAPPTAY---------GFPTAAPGAE-----SG 262

Query: 300 LILVTPGAPTEKDWAQVQALLLP-DAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAG 358
           L L    A    +    +    P  AP+    +    ++ EC G G    P G + + +G
Sbjct: 263 LSLKRKAADEGPEGRYRKYAYEPAKAPVADGASYPAADNGECRGNGFRAKPPGAAEEASG 322

Query: 359 --GGGLE-------------NALSKGREKCSA--GSQKAGSGEGPGKAGSEGLQQVVGMK 401
             GGG+                  K  E+  A  G     SGE P       L+ V    
Sbjct: 323 KYGGGVPLKVLGSPVYGPQLEPFEKFPERAPAPRGGFAVPSGETPKGVDPGALELVTSKM 382

Query: 402 KSGG---------GDSERAAALSPEDETWEVLEEAPPPVFP--LRPG------GLPGLCE 444
              G         G     AAL  E+  W +L    PP +P  LRP       G  G  +
Sbjct: 383 VDCGPPVQWADVAGQGALKAALE-EELVWPLLR---PPAYPGSLRPPRTVLLFGPRGAGK 438

Query: 445 WLRRALPPAQAGALLLAL------PPASPSAARTKAAALRAGAWRPALLASLAAAAAPLP 498
            L       Q GA LL L       P +   AR   AA  A   RP  +  ++   A LP
Sbjct: 439 ALLGRCLATQLGATLLRLRGATLAAPGAAEGARLLQAAFAAARCRPPSVLLISELEALLP 498


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 63/240 (26%), Positives = 85/240 (35%), Gaps = 37/240 (15%)

Query: 379 KAGSGEGPGKAGSEGLQQVVGMKKSGG--GDSERAAALSPEDETWEVLEEAPPPVF---- 432
           + GS    G+A S+  + V    K  G    S    A   +  +W+  E+ P PV+    
Sbjct: 394 RPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ-PDPVWVQSS 452

Query: 433 --------PLRPGGLPGLCEWLR--RALPPAQAGALLLALPPASPSAARTKAAALRAGAW 482
                   P     LP     +    + PP QAG+     P   P +A   AAA+ A A 
Sbjct: 453 VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS-----PLKRPFSA---AAAIAAAAA 504

Query: 483 RPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGELA 542
             A  A+ AAAAAP P L  A   AL               P   A    A   A+   A
Sbjct: 505 AAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASA 564

Query: 543 ARAHF------------PGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAATG 590
           A +H             P P  +   +    A A +   G   L A++   P  GA A G
Sbjct: 565 APSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALG 624


>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
          Length = 1035

 Score = 37.4 bits (85), Expect = 0.042
 Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 7/126 (5%)

Query: 3   PPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGELS 62
           PP+  V++L L PP  G S L     +KDV  L  PE  PD+GV  L    P   +  L 
Sbjct: 454 PPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLR-PE-PPDTGVSHLCPEPPKTRVSHLR 511

Query: 63  CPPAAPG-----PWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNLR 117
             P+  G     P   +  V  L    PE +   L P   E  ++ L    P   + +LR
Sbjct: 512 PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLR 571

Query: 118 PGDSQT 123
           P    T
Sbjct: 572 PEPPDT 577



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 23/137 (16%)

Query: 1   MPPPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGR--PDSGVPSLRAAGPGLFL 58
           + PP+  V+ L+L PPG G    ++ LC +  +T  +   R  P++GVP L    P   +
Sbjct: 260 LEPPETGVSHLYLEPPGTG----VSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRV 315

Query: 59  GELSCPPAAPG-----------------PWAAEANVLVLVLPGPEGNGEPLAPALGEAAL 101
             L   P+  G                 P   E  V  L    PE    PL     EA +
Sbjct: 316 SHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGV 375

Query: 102 AALARGTPLLAVRNLRP 118
           + L    P   V  LRP
Sbjct: 376 SHLCPEPPKTRVPPLRP 392



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 9/127 (7%)

Query: 3   PPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGELS 62
           PP+  V++L L PP  G S L        V +L      P++GV  L    PG  +  L 
Sbjct: 226 PPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEP--PETGVSHLYLEPPGTGVSHL- 282

Query: 63  CPPAAPGPWA------AEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNL 116
           CP       +       E  V  L L  P+     L P   E  ++ L    P   V +L
Sbjct: 283 CPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSL 342

Query: 117 RPGDSQT 123
            P   +T
Sbjct: 343 HPEPPET 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,113,547
Number of Sequences: 37866
Number of extensions: 1776426
Number of successful extensions: 8813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 350
Number of HSP's that attempted gapping in prelim test: 8024
Number of HSP's gapped (non-prelim): 1182
length of query: 623
length of database: 18,247,518
effective HSP length: 108
effective length of query: 515
effective length of database: 14,157,990
effective search space: 7291364850
effective search space used: 7291364850
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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