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Search of human proteins with 13435366
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
(847 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 1716 0.0
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 1694 0.0
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 1146 0.0
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 1132 0.0
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 855 0.0
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 834 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 413 e-115
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 381 e-105
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 355 1e-97
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 351 1e-96
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 348 2e-95
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 330 3e-90
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 323 5e-88
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 320 3e-87
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 318 2e-86
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 300 4e-81
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 295 9e-80
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 260 3e-69
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 260 3e-69
gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 246 8e-65
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 244 3e-64
gi|221316595 cadherin 17 precursor [Homo sapiens] 243 4e-64
gi|221316593 cadherin 17 precursor [Homo sapiens] 243 4e-64
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 237 3e-62
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 233 7e-61
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 230 5e-60
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 225 1e-58
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 223 8e-58
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 214 3e-55
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 214 3e-55
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 1716 bits (4443), Expect = 0.0
Identities = 847/847 (100%), Positives = 847/847 (100%)
Query: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA
Sbjct: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
Query: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL
Sbjct: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
Query: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ
Sbjct: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY
Sbjct: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT
Sbjct: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
Query: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY
Sbjct: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
Query: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV
Sbjct: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
Query: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM
Sbjct: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
Query: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI
Sbjct: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
Query: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD
Sbjct: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
Query: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS
Sbjct: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG
Sbjct: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
Query: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 840
QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR
Sbjct: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 840
Query: 841 GHTLIKN 847
GHTLIKN
Sbjct: 841 GHTLIKN 847
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 1694 bits (4388), Expect = 0.0
Identities = 836/837 (99%), Positives = 837/837 (100%)
Query: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA
Sbjct: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
Query: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL
Sbjct: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
Query: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ
Sbjct: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY
Sbjct: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT
Sbjct: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
Query: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY
Sbjct: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
Query: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV
Sbjct: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
Query: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM
Sbjct: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
Query: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI
Sbjct: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
Query: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD
Sbjct: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
Query: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS
Sbjct: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG
Sbjct: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
Query: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 837
QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGE+
Sbjct: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEK 837
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 1146 bits (2965), Expect = 0.0
Identities = 560/843 (66%), Positives = 669/843 (79%), Gaps = 5/843 (0%)
Query: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
M AA P S GA+C LLLTL I A +ACK V L+VPSKL+A+K++GRVNL+ECF +
Sbjct: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
Query: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
A+LI SSDPDF++L DGSVYT + LS +KRSFTI LS+ Q +K++ V LEHQ KV
Sbjct: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
Query: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
K RHT+E VLRRAKRRWAPIPCSM ENSLGPFPLFLQQV+SD AQNYT++YSI G GVD+
Sbjct: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
EP NLFY+ERDTGNL+CTRPVDRE+Y+ F++IA+A+T DGY+ +LPLPL I++EDENDN+
Sbjct: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
P+FTE Y F + E+ R GTTVG VCATD+DEPDTMHTRLKYSI+ Q P SP LFS+HP+
Sbjct: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
Query: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
TGVITT S LDRE++DKY L +KVQDMDGQ+FGL TSTCII + D ND+ PTF + +Y
Sbjct: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
Query: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
VEEN +VEILR+ +EDKDL+NTANWR N+TILKGNENG+FKI TD +TNEGVL VV
Sbjct: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
Query: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
KPLNYEE +Q+ L+IGV NEAPF+R+ +A++ A VTV+V D DEGPEC P Q VR+
Sbjct: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
Query: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
KEN VG+ NGYKAYDPE R+ +G+RYKKL DP GW+TIDE +GSI + LDRE ET
Sbjct: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
Query: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
KN +YNITVLA D+ R+CTGTL + ++DVNDN P I ++ V+ICKP M +I+AVDPD
Sbjct: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
Query: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
EP+HG PF FSL +++ E+ R+W L +NDTAARLSYQ + F Y +PITV+DR G ++
Sbjct: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
L V LC+C C R R GV LGKWAILAILLGIALLF +L TLVCG G
Sbjct: 661 TKLLRVNLCECTHPTQC--RATSR--STGVILGKWAILAILLGIALLFSVLLTLVCGVFG 716
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
+K K P+DLAQQNLI+SNTEAPGDD+V SANGF TQT S+QG CGT+GSG+KNGG
Sbjct: 717 ATK-GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGG 775
Query: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 840
QETIEM+KGG+QT ESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR
Sbjct: 776 QETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 835
Query: 841 GHT 843
GHT
Sbjct: 836 GHT 838
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 1132 bits (2929), Expect = 0.0
Identities = 553/837 (66%), Positives = 663/837 (79%), Gaps = 5/837 (0%)
Query: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
M AA P S GA+C LLLTL I A +ACK V L+VPSKL+A+K++GRVNL+ECF +
Sbjct: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
Query: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
A+LI SSDPDF++L DGSVYT + LS +KRSFTI LS+ Q +K++ V LEHQ KV
Sbjct: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
Query: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
K RHT+E VLRRAKRRWAPIPCSM ENSLGPFPLFLQQV+SD AQNYT++YSI G GVD+
Sbjct: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
EP NLFY+ERDTGNL+CTRPVDRE+Y+ F++IA+A+T DGY+ +LPLPL I++EDENDN+
Sbjct: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
P+FTE Y F + E+ R GTTVG VCATD+DEPDTMHTRLKYSI+ Q P SP LFS+HP+
Sbjct: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
Query: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
TGVITT S LDRE++DKY L +KVQDMDGQ+FGL TSTCII + D ND+ PTF + +Y
Sbjct: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
Query: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
VEEN +VEILR+ +EDKDL+NTANWR N+TILKGNENG+FKI TD +TNEGVL VV
Sbjct: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
Query: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
KPLNYEE +Q+ L+IGV NEAPF+R+ +A++ A VTV+V D DEGPEC P Q VR+
Sbjct: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
Query: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
KEN VG+ NGYKAYDPE R+ +G+RYKKL DP GW+TIDE +GSI + LDRE ET
Sbjct: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
Query: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
KN +YNITVLA D+ R+CTGTL + ++DVNDN P I ++ V+ICKP M +I+AVDPD
Sbjct: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
Query: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
EP+HG PF FSL +++ E+ R+W L +NDTAARLSYQ + F Y +PITV+DR G ++
Sbjct: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
L V LC+C C R R GV LGKWAILAILLGIALLF +L TLVCG G
Sbjct: 661 TKLLRVNLCECTHPTQC--RATSR--STGVILGKWAILAILLGIALLFSVLLTLVCGVFG 716
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
+K K P+DLAQQNLI+SNTEAPGDD+V SANGF TQT S+QG CGT+GSG+KNGG
Sbjct: 717 ATK-GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGG 775
Query: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 837
QETIEM+KGG+QT ESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGE+
Sbjct: 776 QETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEK 832
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 855 bits (2209), Expect = 0.0
Identities = 450/850 (52%), Positives = 590/850 (69%), Gaps = 17/850 (2%)
Query: 4 ARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANL 63
A S + C+ LL +L +L DAC+ V L VPS L AE LVG+VNL+EC +A+L
Sbjct: 2 ALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASL 61
Query: 64 IHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLE-HQTKVLKK 122
I SSDP F+ILEDGS+YTT+ ++LSSE++SF+I LS+ + +E+++I V L + K KK
Sbjct: 62 IRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKK 121
Query: 123 RHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEP 182
RHTK+ L+R+KRRWAPIP S++ENSLGPFP +QQ+QSD AQNYTI+YSI GPGVD+EP
Sbjct: 122 RHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEP 181
Query: 183 RNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPI 242
NLFY+E+DTG+++CTR +DRE+YE F + +ATT DGY PE PLPLIIKIED+NDN P
Sbjct: 182 FNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPY 241
Query: 243 FTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTG 302
F FT+ ENCR GT+VG+V ATD DEPDT+HTRLKY I+ Q+P P FS+HP TG
Sbjct: 242 FEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTG 301
Query: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
VITTT+ LDRE D YQL ++V+DM GQ FGL T T I+++D ND+ P+FT TSYVT
Sbjct: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
Query: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
VEEN +DVEILR+ V+D+DL NT + +A Y IL+GNENGNF I TD TNEGVLCVVKP
Sbjct: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
Query: 423 LNYEEKQQMILQIGVVNEAPFSREASPRS-AMSTATVTVNVEDQDEGPECNPPIQTVRMK 481
LNYE +Q+ILQ+GV+NEA FS+ AS ++ M T TVTV + D DEGPEC+PP++ ++ +
Sbjct: 422 LNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQ 481
Query: 482 ENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
+ G GYKA DPE S G+RY+KL D W I+++TG ++ + LDRE++ +K
Sbjct: 482 DGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
Query: 542 NGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
N YNI+V+A D GR+CTGTL + L D ND++P I K+ V IC+ A + VDPD
Sbjct: 542 NNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDG 600
Query: 602 PIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSV 661
P +GPPF F L++S S + W ++ + A L + + + Y VPI ++DR G+ +
Sbjct: 601 PENGPPFQFFLDNSAS---KNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVAT 657
Query: 662 TSLDVTLCDCITENDCTHR-VDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
L V +CDC T ++C + R V LG+WAILA++LG LL CILFT C +
Sbjct: 658 HMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFC-VTA 716
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSAN---GFTTQTVGASAQGVCGTVGSGIK 777
K P+D+AQQNLIVSNTE PG++ V AN T + ++ V G GIK
Sbjct: 717 KRTVKKCFPEDIAQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIK 775
Query: 778 NGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 837
Q++ EMVKGG+ T +S +G G H TL+S + G + D RY Y++W SFTQPRLGEE
Sbjct: 776 T--QQSFEMVKGGY-TLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEE 830
Query: 838 SIRGHTLIKN 847
SIRGHTLIKN
Sbjct: 831 SIRGHTLIKN 840
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 834 bits (2154), Expect = 0.0
Identities = 439/840 (52%), Positives = 580/840 (69%), Gaps = 17/840 (2%)
Query: 4 ARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANL 63
A S + C+ LL +L +L DAC+ V L VPS L AE LVG+VNL+EC +A+L
Sbjct: 2 ALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASL 61
Query: 64 IHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLE-HQTKVLKK 122
I SSDP F+ILEDGS+YTT+ ++LSSE++SF+I LS+ + +E+++I V L + K KK
Sbjct: 62 IRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKK 121
Query: 123 RHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEP 182
RHTK+ L+R+KRRWAPIP S++ENSLGPFP +QQ+QSD AQNYTI+YSI GPGVD+EP
Sbjct: 122 RHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEP 181
Query: 183 RNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPI 242
NLFY+E+DTG+++CTR +DRE+YE F + +ATT DGY PE PLPLIIKIED+NDN P
Sbjct: 182 FNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPY 241
Query: 243 FTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTG 302
F FT+ ENCR GT+VG+V ATD DEPDT+HTRLKY I+ Q+P P FS+HP TG
Sbjct: 242 FEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTG 301
Query: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
VITTT+ LDRE D YQL ++V+DM GQ FGL T T I+++D ND+ P+FT TSYVT
Sbjct: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
Query: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
VEEN +DVEILR+ V+D+DL NT + +A Y IL+GNENGNF I TD TNEGVLCVVKP
Sbjct: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
Query: 423 LNYEEKQQMILQIGVVNEAPFSREASPRS-AMSTATVTVNVEDQDEGPECNPPIQTVRMK 481
LNYE +Q+ILQ+GV+NEA FS+ AS ++ M T TVTV + D DEGPEC+PP++ ++ +
Sbjct: 422 LNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQ 481
Query: 482 ENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
+ G GYKA DPE S G+RY+KL D W I+++TG ++ + LDRE++ +K
Sbjct: 482 DGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
Query: 542 NGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
N YNI+V+A D GR+CTGTL + L D ND++P I K+ V IC+ A + VDPD
Sbjct: 542 NNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDG 600
Query: 602 PIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSV 661
P +GPPF F L++S S + W ++ + A L + + + Y VPI ++DR G+ +
Sbjct: 601 PENGPPFQFFLDNSAS---KNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVAT 657
Query: 662 TSLDVTLCDCITENDCTHR-VDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
L V +CDC T ++C + R V LG+WAILA++LG LL CILFT C +
Sbjct: 658 HMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFC-VTA 716
Query: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSAN---GFTTQTVGASAQGVCGTVGSGIK 777
K P+D+AQQNLIVSNTE PG++ V AN T + ++ V G GIK
Sbjct: 717 KRTVKKCFPEDIAQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIK 775
Query: 778 NGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 837
Q++ EMVKGG+ T +S +G G H TL+S + G + D RY Y++W SFTQPRLGE+
Sbjct: 776 T--QQSFEMVKGGY-TLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEK 830
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 413 bits (1062), Expect = e-115
Identities = 259/719 (36%), Positives = 380/719 (52%), Gaps = 46/719 (6%)
Query: 66 SSDP-DFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRH 124
SS+P DF++ EDG VY + LSSE F I + E QEK ++ V L LK
Sbjct: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLS-----LKPTL 127
Query: 125 TKEKV---------------------LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT 163
T+E V L+R KR W P ++ ENS GPFP L +++SD
Sbjct: 128 TEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDR 187
Query: 164 AQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP 223
+N ++ YS+ GPG DQ P +F + +G L T+P+DREQ F + A A +G
Sbjct: 188 DKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQV 247
Query: 224 ELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYS 283
E P+ ++I + D NDN P F + + T+ E + GT V V A D D+P+ ++ L+Y
Sbjct: 248 ENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYR 307
Query: 284 IIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQ-YFGLQTTST 340
I+ Q P PSP +F+++ TG I T ++ LDRE + +Y L I+ DM+G +GL T+T
Sbjct: 308 IVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTAT 367
Query: 341 CIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNE 400
+I + DVND+ P FT ++ V EN VD+ + +TV DKD +T W A Y I G+
Sbjct: 368 AVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDP 427
Query: 401 NGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTV 460
G F I TD +N+G++ VVKP+++E + +L + N+ P ++ STATV+V
Sbjct: 428 TGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK-GIQHPPQSTATVSV 486
Query: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
V D +E P P + +R +E GT + A DP+ IRY KL+DP W+ I
Sbjct: 487 TVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKI 546
Query: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
D G I LDRE+ +KN IYN T LASD G + TGTL I L D+NDN+P +
Sbjct: 547 DPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL 606
Query: 579 KKTVIICK-PTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSY 637
+ C+ P +S I A+D D + PF F L S ++R W + +N A+L+
Sbjct: 607 PQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNL 666
Query: 638 Q-NDPPFGSYVVPITVRD--RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
+ G Y VPI + D S+++ L V +C C + DCT VD +G G LG
Sbjct: 667 KIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-VDRIVGAG---LGT 722
Query: 695 WAILAILLGIALLFCILFTLVC-----GASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
AI+AILL I +L ++ V +KQ + P+D + N++ + E G++
Sbjct: 723 GAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 381 bits (979), Expect = e-105
Identities = 248/750 (33%), Positives = 389/750 (51%), Gaps = 51/750 (6%)
Query: 43 LDAEKLVGRVNLKECF-TAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNT 101
L+ EKL+ +V C T ++ DF++ DG+V+ T + + SE+ +FT+ ++
Sbjct: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
Query: 102 ENQEKKKIFVFL----------EHQTKVLKK------------------RHTKEKVLRRA 133
+ EK V L H+ + KK +H LRR
Sbjct: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
Query: 134 KRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTG 193
KR W P ++ ENS GPFP L +++SD + I YSI G G DQ P +F ++ +G
Sbjct: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
Query: 194 NLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIF 253
+Y TRP+DRE++ S+ + A A +G E P+ L I + D NDN P F + Y ++
Sbjct: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
Query: 254 ENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPT--LFSMHPTTGVITTTSSQL 311
E + GT V V A D D+ T + ++Y I+ Q P SP+ +F+++ TG I T ++ L
Sbjct: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
Query: 312 DRELIDKYQLKIKVQDMDGQY-FGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVD 370
DRE + +Y + ++ DM+G +GL T+T II + DVND+ P FT +++ V EN V+
Sbjct: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
Query: 371 VEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQ 430
+ +TV D+D ++ NW A Y I+ G+ +G+F + TD TNEG++ VVK ++YE +
Sbjct: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
Query: 431 MILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTS 490
+L + V N+AP + S STA VT+++ D +E P + +R++E GT
Sbjct: 468 FMLTVMVSNQAPLA-SGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
Query: 491 NGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL 550
+ A DP+ +RY KL+DP W+ I+ G I LDRE+ KN +Y T L
Sbjct: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
Query: 551 ASDQG--GRTCTGTLGIILQDVNDNSP-FIPKKTVIICKPTMSSAEIVAVDPDEPIHGPP 607
A+D G + TGTL I L D+NDN+P +PK+ I KP +++ I A D D + P
Sbjct: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
Query: 608 FDFSLESSTSEVQRMWRLKAINDTAARLSYQ-NDPPFGSYVVPITVRD--RLGMSSVTSL 664
+ F L + V++ W + +N A+LS + G Y VPI V D +S+ + +
Sbjct: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSII 706
Query: 665 DVTLCDCITENDCTHRVDPRIGG-GGVQLGKWAILAILLGIALLFCILFTLVCGASGT-- 721
V +C C DCT IG LG AI+AIL+ I +L ++ V
Sbjct: 707 KVKVCPCDDNGDCT-----TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREK 761
Query: 722 ---SKQPKVIPDDLAQQNLIVSNTEAPGDD 748
+KQ + P+D + N++ + E G++
Sbjct: 762 ERHTKQLLIDPEDDVRDNILKYDEEGGGEE 791
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 355 bits (911), Expect = 1e-97
Identities = 247/776 (31%), Positives = 381/776 (49%), Gaps = 49/776 (6%)
Query: 8 GSWNGALCRLLLL--TLAILIFASDAC------KNVTLHVPSK-LDAEKLVGRVNLKECF 58
G W+ +L LLLL + L + C ++ T VP + L+ +++GRVN ++C
Sbjct: 2 GPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCT 61
Query: 59 TAANLIHSS-DPDFQILEDGSVYTTNTILLSSEKRSFTILL-SNTENQEKKKIFVFL--- 113
+ S D F++ DG + + + + F + +T + K+ +
Sbjct: 62 GRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGH 121
Query: 114 -----EHQTKV------LKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSD 162
HQ V L LRR KR W P S EN GPFP L Q++S+
Sbjct: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
Query: 163 TAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYT 222
+ ++YSI G G D P +F +ER+TG L T P+DRE+ ++ + + A + +G
Sbjct: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
Query: 223 PELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEP-DTMHTRLK 281
E P+ ++I + D+NDN P FT+E + ++ E GT+V +V ATD D+ +T + +
Sbjct: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
Query: 282 YSIIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTS 339
Y+I+ Q P P +F+++ TGVI+ ++ LDRE Y L ++ D+ G+ GL TT+
Sbjct: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Query: 340 TCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGN 399
T +I + D ND+ P F T+Y V EN +V I + V D D NT W A YTIL +
Sbjct: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
Query: 400 ENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVT 459
+ G F + T+ N+G+L K L++E KQQ IL + V N PF + STATVT
Sbjct: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT----TSTATVT 474
Query: 460 VNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVT 519
V+V D +E P PP + V + E+ VG Y A +P+T I Y+ D W+
Sbjct: 475 VDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLE 534
Query: 520 IDENTGSIKVFRSLDRE-AETIKNGIYNITVLASDQGG--RTCTGTLGIILQDVNDNSPF 576
I+ +TG+I LDRE E +KN Y ++A+D G T TGTL +IL DVNDN+P
Sbjct: 535 INPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI 594
Query: 577 IPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLS 636
+T+ C+ I +D D P + PF L T W ++ + T +
Sbjct: 595 PEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAEL---THGASANWTIQYNDPTQESII 651
Query: 637 YQNDPPF--GSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
+ G Y + + + D VT+L+V++CDC + P G +
Sbjct: 652 LKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIP--- 708
Query: 695 WAILAILLGI--ALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
AIL IL GI L+ +L L K+P + P+D + N+ + E G++
Sbjct: 709 -AILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 351 bits (901), Expect = 1e-96
Identities = 229/633 (36%), Positives = 334/633 (52%), Gaps = 24/633 (3%)
Query: 130 LRRAKRRWAPIPCSMLENSLG-PFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYV 188
L R +R W P S+ EN P+PL Q++SD Q ++ YSI+GPGVD+EPR +F +
Sbjct: 40 LSRVRRAWVIPPISVSENHKRLPYPLV--QIKSDKQQLGSVIYSIQGPGVDEEPRGVFSI 97
Query: 189 ERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETY 248
++ TG ++ +DRE+ + F + AFA G T E P L I + D+NDN P F +E +
Sbjct: 98 DKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAF 157
Query: 249 TFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVITTTS 308
T + E GT V + ATD D+P+T + L++SI+ Q SP LFS+ TG I T
Sbjct: 158 TGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQ--GSPELFSIDELTGEIRTVQ 215
Query: 309 SQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENT 368
LDRE++ Y L ++V DM G GL T++ II +DD+ND+ P FTR + E
Sbjct: 216 VGLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEAV 273
Query: 369 VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEK 428
V++ R+ VED+DL + NW A +TIL+G+ +G F I TD KTNEGVL +VK L+YE
Sbjct: 274 SGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESC 333
Query: 429 QQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGT 488
+ L++ V NEAP + A+ R+ A V V+V+D +E P + E A GT
Sbjct: 334 EHYELKVSVQNEAPL-QAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGT 392
Query: 489 TSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNIT 548
+ A DP+T + Y K DP W+ +D TG I+ L + +K G Y
Sbjct: 393 LVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAI 452
Query: 549 VLASDQGG--RTCTGTLGIILQDVNDNSPFI-PKKTVIICKPTMSSAEIV--AVDPDEPI 603
VLA D RT TGTL I + +VND++P + P +C ++ A D D P
Sbjct: 453 VLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDLPP 512
Query: 604 HGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRD--RLGMSSV 661
HG PF F L E+ R W L +N + ARL ++ P G + + + +RD +
Sbjct: 513 HGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPPQQRE 572
Query: 662 TSLDVTLCDCITENDCTHRVDPRIGGG-GVQLGKWAILAILLGIALLFCILFTLVCGASG 720
L+VT+C C + C + GG G+ LG L I+L ALL +L LV +
Sbjct: 573 QPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLG---ALVIVLASALLLLVLVLLVALRAR 629
Query: 721 TSKQPKVI-----PDDLAQQNLIVSNTEAPGDD 748
KQ + P D + N++ + + G++
Sbjct: 630 FWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEE 662
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 348 bits (892), Expect = 2e-95
Identities = 226/669 (33%), Positives = 347/669 (51%), Gaps = 30/669 (4%)
Query: 86 LLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSML 145
L S++ FT+ T + + L+ + + K +++LRR KR W P S+
Sbjct: 65 LFSTDNDDFTVRNGETVQERRS-----LKERNPL--KIFPSKRILRRHKRDWVVAPISVP 117
Query: 146 ENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQ 205
EN GPFP L Q++S+ ++ I+YSI GPG D P +F VE++TG L +P+DRE+
Sbjct: 118 ENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREE 177
Query: 206 YESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQV 265
+E+ A + +G + E P+ + I + D+ND+ P FT++T+ ++ E GT+V QV
Sbjct: 178 IAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQV 237
Query: 266 CATDKDEP-DTMHTRLKYSIIGQVPPSP--TLFSMHPTTGVITTTSSQLDRELIDKYQLK 322
ATD+D+ T + + YSI Q P P +F++H +TG I+ SS LDRE + +Y L
Sbjct: 238 TATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLT 297
Query: 323 IKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKD 382
I+ DMDG G TT+ ++ I D ND+ P F Y V EN V E+ R+TV D D
Sbjct: 298 IQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLD 355
Query: 383 LVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAP 442
N+ WRA Y I+ G++ +F I T ++N+G+L K L++E K Q L + V NEAP
Sbjct: 356 APNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAP 415
Query: 443 FSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRS 502
F + STAT+ V+VED +E P PP + V ++E G Y A DP+ +
Sbjct: 416 FVL----KLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KE 470
Query: 503 SSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET-IKNGIYNITVLASDQGG--RTC 559
+ I Y+ L DP GW+ +D ++G + +LDRE E ++N IY + VLA D G T
Sbjct: 471 NQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTG 530
Query: 560 TGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEV 619
TGTL + L DVND+ P + + IC + + D D H PF L + S++
Sbjct: 531 TGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQL-TDDSDI 589
Query: 620 QRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTH 679
+ DT LS + +Y V +++ D +T + T+CDC +
Sbjct: 590 YWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETC- 647
Query: 680 RVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIV 739
P GG L +L +L + L +L LV K+P ++P+D + N+
Sbjct: 648 ---PGPWKGGFIL---PVLGAVLALLFLLLVLLLLV-RKKRKIKEPLLLPEDDTRDNVFY 700
Query: 740 SNTEAPGDD 748
E G++
Sbjct: 701 YGEEGGGEE 709
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 330 bits (847), Expect = 3e-90
Identities = 229/674 (33%), Positives = 343/674 (50%), Gaps = 20/674 (2%)
Query: 14 LCRLLLLTLAILIFASDACKNVTLHV--PSKLDAEKLVGRVNLKECFTAANLIHS-SDPD 70
L ++LLLT A + + + H+ P++ ++ + + +C L + S P
Sbjct: 13 LSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPY 72
Query: 71 FQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKK-RHTKEKV 129
F++ DG + I + + E+ + I + Q + + +
Sbjct: 73 FKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSP 132
Query: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVE 189
+ R KR P + EN PFP + +V D+ + + + G GVDQEP+ +F +
Sbjct: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRIN 191
Query: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYT 249
+TG++ TR +DRE +++ T +G T E P+PL + + D+NDN PIF E Y
Sbjct: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
Query: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMHPTTGVITTT 307
+ E GTTV ++ A D D+P T + L+Y+I Q P PSP +F + P G I T
Sbjct: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
Query: 308 SSQ--LDRELID--KYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTS 363
S LDRE ++ KY+L I+ QDM G GL T+T I IDD NDH P FT+ + +
Sbjct: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371
Query: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
VEE V V I+ +TVEDKD T WRA YTI+ GN +F+I T+ +TNEG+L VVKPL
Sbjct: 372 VEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
Query: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
+YE L I V NE P + S STATV + V D +EGP P V +E+
Sbjct: 431 DYEISAFHTLLIKVENEDPLVPDVS-YGPSSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
Query: 484 AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNG 543
VG+ A DP++ IRY DP GW+ I+ G++ LDRE+ + N
Sbjct: 490 LSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNS 549
Query: 544 IYNITVLASDQGG--RTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
+Y LA D G T TGTL I L+DVNDN+PFI +C + + ++ D+
Sbjct: 550 VYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDK 609
Query: 602 PIH--GPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRD--RLG 657
+H PF F + + ++W++ IN+T A +S + +Y +PI V D +
Sbjct: 610 DLHPNTDPFKFEIHKQ-AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPP 668
Query: 658 MSSVTSLDVTLCDC 671
M+++T L V +C C
Sbjct: 669 MTNITDLRVQVCSC 682
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 323 bits (827), Expect = 5e-88
Identities = 226/718 (31%), Positives = 339/718 (47%), Gaps = 60/718 (8%)
Query: 125 TKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRN 184
TK + +RR KR W + E + +++SD N I Y I G G+D+ P
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 185 LFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFT 244
+F + TG + T VDRE F I A G E PL L +K+ D NDN P+F+
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 245 EETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVI 304
+ YT +I EN T V ++CATD DE + +++++ Y I+ Q P +F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364
T SS LDRE Y L ++ D DG GL + C I + DVND+ PT +TSY S+
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 365 EENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLN 424
EEN + E++R+ D D T NW A Y IL GN+ F I TD +TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 425 YEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENA 484
YE+ + L IGV N+A F + + M V + V D EGP +P ++E
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398
Query: 485 EVGTTSN----GYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539
+ + N Y A D +T ++ +RY D W+ ID TG I+ R D++++
Sbjct: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458
Query: 540 IKNGIYNITVLASDQG-GRTCTGTLGIILQDVNDNSP--FIPKKTVIICKPTMSSAEIVA 596
I NGIY +LA D G G+T TGT+ I + D+ND P F ++T+ I P+ V
Sbjct: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPS------VL 512
Query: 597 VDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRL 656
+ +E +G PF F + + MW +++ N T+A L+ + G Y +PI V+D
Sbjct: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 657 GMSSVTSLDVTL--CDCITENDCTHR------------------VDPRIGGGGVQLGKWA 696
+ + V L CDC + C + + G V LG
Sbjct: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632
Query: 697 ILAILLGIALLFC--ILFTLVC------------------GASGTSKQPKV---IPDDLA 733
I ++LGI LL +L L C G G + ++ P+D
Sbjct: 633 IGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRD 692
Query: 734 QQNLIVSNTEAPGDDKVYSANGFT-TQTVGASAQGVCGTVGSGIKNGGQETIEMVKGG 790
N+ T + D++ S+ +T T G + +G G G + G + ++ G
Sbjct: 693 VSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEG--GVSGVELNTGMGTAVGLMAAG 748
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 320 bits (820), Expect = 3e-87
Identities = 210/621 (33%), Positives = 307/621 (49%), Gaps = 35/621 (5%)
Query: 125 TKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRN 184
TK + +RR KR W + E + +++SD N I Y I G G+D+ P
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 185 LFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFT 244
+F + TG + T VDRE F I A G E PL L +K+ D NDN P+F+
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 245 EETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVI 304
+ YT +I EN T V ++CATD DE + +++++ Y I+ Q P +F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364
T SS LDRE Y L ++ D DG GL + C I + DVND+ PT +TSY S+
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 365 EENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLN 424
EEN + E++R+ D D T NW A Y IL GN+ F I TD +TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 425 YEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENA 484
YE+ + L IGV N+A F + + M V + V D EGP +P ++E
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398
Query: 485 EVGTTSN----GYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539
+ + N Y A D +T ++ +RY D W+ ID TG I+ R D++++
Sbjct: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458
Query: 540 IKNGIYNITVLASDQG-GRTCTGTLGIILQDVNDNSP--FIPKKTVIICKPTMSSAEIVA 596
I NGIY +LA D G G+T TGT+ I + D+ND P F ++T+ I P+ V
Sbjct: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPS------VL 512
Query: 597 VDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRL 656
+ +E +G PF F + + MW +++ N T+A L+ + G Y +PI V+D
Sbjct: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 657 GMSSVTSLDVTL--CDCITENDCTHR------------------VDPRIGGGGVQLGKWA 696
+ + V L CDC + C + + G V LG
Sbjct: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632
Query: 697 ILAILLGIALLFCI-LFTLVC 716
I ++LGI LL L L+C
Sbjct: 633 IGMMVLGILLLILAPLLLLLC 653
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 318 bits (814), Expect = 2e-86
Identities = 213/653 (32%), Positives = 332/653 (50%), Gaps = 32/653 (4%)
Query: 113 LEHQTKVLKKRHTKEKV---LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTI 169
++ +T L K+ TKEK+ LRR+KRRW + E GPFP + ++ ++ + N ++
Sbjct: 30 VQQETDDLTKQ-TKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSL 88
Query: 170 YYSIRGPGVDQEPR-NLFYVE-RDTGNLYCTRPVDREQYESFEI-IAFATTPDGYTPELP 226
Y I GPGVD+ P LF +E + G +Y RPVDRE SF + G +
Sbjct: 89 MYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTS 148
Query: 227 LPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIG 286
L I+I D ND+ P F E+ + T+ EN G + Q+ A D DE +T ++++ Y +I
Sbjct: 149 LIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLIS 208
Query: 287 QVPP-SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINI 345
Q P + F + +G I S LD E ++ L I+ +D L +T+T +++
Sbjct: 209 QTPLLKESGFRVDRLSGEIRL-SGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDV 265
Query: 346 DDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFK 405
+ N+H P FT+ +Y + E +LR+ V+D+D T+ WRA + IL GNE G+F
Sbjct: 266 QEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFD 325
Query: 406 IVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPF-----SREASPRSAMSTATVTV 460
I TD +TNEG+L V+KPL+YE + L I V NE + PR A ++ATV+V
Sbjct: 326 ISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSV 385
Query: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
V D ++ P +P V +E A GT + A DP+ S IRY+ + DP WV++
Sbjct: 386 QVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDPANWVSV 441
Query: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
D+N+G + +DRE+ + N Y I + A D G +T TGTL + L D+NDN P +
Sbjct: 442 DKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLR 501
Query: 579 KKT--VIICKPTM-SSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL 635
++ + +C+ + I A DPD PF F L+++ + W+L + L
Sbjct: 502 PRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL 561
Query: 636 SYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKW 695
P G+Y+VP+ + D+ G+S ++ V +C C + C D +G L
Sbjct: 562 LTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPV 621
Query: 696 AILAILLGIALLFCI--LFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPG 746
+ L +ALLF + F L G S + +D Q L++ N E+ G
Sbjct: 622 CAAFVALAVALLFLLRCYFVLEPKRHGCS-----VSNDEGHQTLVMYNAESKG 669
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 300 bits (768), Expect = 4e-81
Identities = 212/700 (30%), Positives = 339/700 (48%), Gaps = 26/700 (3%)
Query: 126 KEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQN--YTIYYSIRGPGVDQEPR 183
K L R KR W P ++ E + ++ SD A+ I Y G G+ + P
Sbjct: 40 KHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPF 99
Query: 184 NLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIF 243
+F +DTG L T +DRE+ F + +A G E PL L IK+ D NDN P+F
Sbjct: 100 GIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVF 159
Query: 244 TEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGV 303
T++ + ++ E T V ++ ATD DEP+T+++++ Y I+ P P +F ++ TG
Sbjct: 160 TQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGE 219
Query: 304 ITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCI-INIDDVNDHLPTFTRTSYVT 362
I TTS LDRE Y L ++ +D +G+ + I I DVND++P
Sbjct: 220 IYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEG 279
Query: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
VEEN V+VE+ R+ V D D + + NW AN+T GNE G F I TDA+TNEG++ ++K
Sbjct: 280 MVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKE 339
Query: 423 LNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKE 482
++YEE + + + V N+A F + + + + V V++ EG + ++ + E
Sbjct: 340 VDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSE 399
Query: 483 N---AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539
+ + G ++A+D +T + RY KL D W+++D T IK+ + D E+
Sbjct: 400 SMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRY 459
Query: 540 IKNGIYNITVLA--SDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAV 597
++NG Y + ++A D +T TGT+ I ++D+NDN P + + IC + A
Sbjct: 460 VQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDA-EYVNVTAE 518
Query: 598 DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLG 657
D D + PF FS+ + W++ A ++ + L Q++ G + + D G
Sbjct: 519 DLDGHPNSGPFSFSVIDKPPGMAEKWKI-ARQESTSVLLQQSEKKLGRSEIQFLISDNQG 577
Query: 658 MSSVTS--LDVTLCDCITENDCTH-RVDPRIGGGGVQLGKWAILAILLGIALLFCI-LFT 713
S L +T+C+C+ + C + D +G LG AI ++L LL + L
Sbjct: 578 FSCPEKQVLTLTVCECLHGSGCREAQHDSYVG-----LGPAAIALMILAFLLLLLVPLLL 632
Query: 714 LVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVG 773
L+C +K IP + + +N AP +DKV + F G S G G VG
Sbjct: 633 LMCHCGKGAKGFTPIPGTIEMLH-PWNNEGAPPEDKVVPS--FLPVDQGGSLVGRNG-VG 688
Query: 774 SGIKNG---GQETIEMVKGGHQTSESCRGAGHHHTLDSCR 810
K G + +VKG H+ SE H +L S R
Sbjct: 689 GMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR 728
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 295 bits (756), Expect = 9e-80
Identities = 220/701 (31%), Positives = 336/701 (47%), Gaps = 51/701 (7%)
Query: 125 TKEKVLRRAKRRWAPI--PCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEP 182
T ++ RR KR W PC E++ P+ ++ SD I Y I G G+DQ P
Sbjct: 39 TMQQAKRRQKREWVKFAKPCREGEDNSKRNPI--AKITSDYQATQKITYRISGVGIDQPP 96
Query: 183 RNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPI 242
+F V+++TG++ T VDRE+ SF I A G E PL L +KI D NDN P+
Sbjct: 97 FGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPV 156
Query: 243 FTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTG 302
F+++ + I EN + V + ATD DEP+ +++++ + I+ Q P +F + TG
Sbjct: 157 FSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTG 216
Query: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
+ T ++ LDRE Y+L + D DG+ GL T C I + DVND+ P F + Y
Sbjct: 217 EVRTLTNSLDREQASSYRLVVSGADKDGE--GLSTQCECNIKVKDVNDNFPMFRDSQYSA 274
Query: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
+EEN + E+LR V D D T NW A Y GNE F+I TD +TNEG+L VVK
Sbjct: 275 RIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKA 334
Query: 423 LNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKE 482
L+YE+ Q + L I V N+A F + R + + VT+ V + EG P +T +++
Sbjct: 335 LDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQK 394
Query: 483 NAE----VGTTSNGYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREA 537
V Y+A D +T +++S ++Y + G++ ID T IK ++++R++
Sbjct: 395 GISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDS 454
Query: 538 ETIKNGIYNITVLASDQ-GGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVA 596
I N VLA D+ G+T TGT+ + + D NDN P + +C + S + +V+
Sbjct: 455 TFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVC--SSSPSVVVS 512
Query: 597 VDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRD-- 654
+ P+ F+LE ++ +W + +N T+A L Q P G Y + + + D
Sbjct: 513 ARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQ 572
Query: 655 --RLGMSSVTSLDVTLCD----CITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLF 708
R M +L+V CD C T T +LG AI +LLG+ LL
Sbjct: 573 NNRCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLL 632
Query: 709 ---CILFTLVCGA-----------------SGTSKQ---PKVIPDDLAQQNLIVSNTEAP 745
+L T CGA GT Q P+D N+ V A
Sbjct: 633 LAPLLLLTCDCGAGSTGGVTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTAN 692
Query: 746 GDDKVYSANGFT-TQTVGASAQGVCG-----TVGSGIKNGG 780
G D + S+ T T G + +G G +G+ ++GG
Sbjct: 693 GADFMESSEVCTNTYARGTAVEGTSGMEMTTKLGAATESGG 733
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 260 bits (665), Expect = 3e-69
Identities = 205/636 (32%), Positives = 320/636 (50%), Gaps = 37/636 (5%)
Query: 132 RAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLFYVER 190
R KR W +LE +G PL++ ++ SD + + +I Y + G G ++F ++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 191 DTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETYT 249
+TG+++ T+ +DRE+ + + A A P P +IKI+D NDN P F + YT
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTTS 308
+ E VGT+V QV ATD D+P ++ R+ YSI+ P FS+ P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 309 SQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENT 368
+DRE D+Y L I+ +DM GQ GL T++ + + DVND+ P F R SY +V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 369 -VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEE 427
V + R+ D D+ AN Y I+ G+ G FKI D +T EG++ + K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 428 KQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVG 487
K L+I N+ R S T TV + VED DE P + P+ + + E +VG
Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVG 393
Query: 488 TTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIY 545
A+DP++ S+S +RY + TD + ID N+G I +SLDRE N I+
Sbjct: 394 NIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIH 448
Query: 546 NITVLA--SDQGGRTCTGTLGIILQDVNDNSP-FIPKKTVIIC---KPTMSSAEIVAVDP 599
NITVLA S + G + I + D+NDN+P F +C +P +I AVD
Sbjct: 449 NITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDK 508
Query: 600 DEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQND---PPFGSYVVPITVRD-- 654
DEP +G F FSL + + ++TA+ L+ +N Y +PI + D
Sbjct: 509 DEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSG 568
Query: 655 RLGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLGKWAILAILLGIALLFCILFT 713
+SS +L + +CDC + T + + G+ G A++AI L L +L
Sbjct: 569 SPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTG--ALIAI-LACVLTLLVLIL 625
Query: 714 LVCGASGTSKQPKVIPDDL-AQQNLIVSNTEAPGDD 748
L+ K+P + ++ ++N++ + E G++
Sbjct: 626 LIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEE 661
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 260 bits (665), Expect = 3e-69
Identities = 205/636 (32%), Positives = 320/636 (50%), Gaps = 37/636 (5%)
Query: 132 RAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLFYVER 190
R KR W +LE +G PL++ ++ SD + + +I Y + G G ++F ++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 191 DTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETYT 249
+TG+++ T+ +DRE+ + + A A P P +IKI+D NDN P F + YT
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTTS 308
+ E VGT+V QV ATD D+P ++ R+ YSI+ P FS+ P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 309 SQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENT 368
+DRE D+Y L I+ +DM GQ GL T++ + + DVND+ P F R SY +V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 369 -VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEE 427
V + R+ D D+ AN Y I+ G+ G FKI D +T EG++ + K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 428 KQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVG 487
K L+I N+ R S T TV + VED DE P + P+ + + E +VG
Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVG 393
Query: 488 TTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIY 545
A+DP++ S+S +RY + TD + ID N+G I +SLDRE N I+
Sbjct: 394 NIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIH 448
Query: 546 NITVLA--SDQGGRTCTGTLGIILQDVNDNSP-FIPKKTVIIC---KPTMSSAEIVAVDP 599
NITVLA S + G + I + D+NDN+P F +C +P +I AVD
Sbjct: 449 NITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDK 508
Query: 600 DEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQND---PPFGSYVVPITVRD-- 654
DEP +G F FSL + + ++TA+ L+ +N Y +PI + D
Sbjct: 509 DEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSG 568
Query: 655 RLGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLGKWAILAILLGIALLFCILFT 713
+SS +L + +CDC + T + + G+ G A++AI L L +L
Sbjct: 569 SPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTG--ALIAI-LACVLTLLVLIL 625
Query: 714 LVCGASGTSKQPKVIPDDL-AQQNLIVSNTEAPGDD 748
L+ K+P + ++ ++N++ + E G++
Sbjct: 626 LIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEE 661
>gi|119703744 desmoglein 1 preproprotein [Homo sapiens]
Length = 1049
Score = 246 bits (627), Expect = 8e-65
Identities = 148/446 (33%), Positives = 227/446 (50%), Gaps = 2/446 (0%)
Query: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVE 189
+RR KR W + E + ++ SD A N + Y I G G+DQ P +F +
Sbjct: 44 IRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVIN 103
Query: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYT 249
+ TG + T VDRE F I A G E PL L +++ D NDN P+F+ T+
Sbjct: 104 QKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFA 163
Query: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVITTTSS 309
I EN T V + ATD DEP+ +++++ + II Q P +F ++ TG I T ++
Sbjct: 164 GQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNN 223
Query: 310 QLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTV 369
LDRE +Y L ++ D DG G+ C I I DVND++P ++SY ++ENT+
Sbjct: 224 FLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTL 283
Query: 370 DVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQ 429
+ +L + V D D +ANW A + GNE F+I + +TN G+L VVKPL+YE Q
Sbjct: 284 NSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQ 343
Query: 430 QMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTT 489
+ L IGV N+A F + + + ++V V + EGP P +T + N
Sbjct: 344 SLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDK 403
Query: 490 SNGYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNIT 548
+ A D +T R S+ +RY +P + +D TG + + + +E + G Y T
Sbjct: 404 VGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGT 463
Query: 549 VLASDQG-GRTCTGTLGIILQDVNDN 573
+L+ D RTCTGT+ I +Q ++
Sbjct: 464 ILSIDDNLQRTCTGTININIQSFGND 489
Score = 36.2 bits (82), Expect = 0.13
Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 23/149 (15%)
Query: 472 NPPIQTV-----RMKENAEVGTTSNGYKAYDPETRSS--SGIRYKKLTDPTG---WVTID 521
NPP+ ++ +++EN+ T A D + ++ S I +K + I+
Sbjct: 153 NPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIIN 212
Query: 522 ENTGSIKVFRS-LDREAETIKNGIYNITVLASDQGG----RTCTGTLGIILQDVNDNSPF 576
NTG I+ + LDRE + G Y + V SD+ G + I + DVNDN P+
Sbjct: 213 RNTGEIRTMNNFLDRE----QYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPY 268
Query: 577 IPKK--TVIICKPTMSS--AEIVAVDPDE 601
+ + T+ I + T++S EI +D DE
Sbjct: 269 MEQSSYTIEIQENTLNSNLLEIRVIDLDE 297
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 244 bits (622), Expect = 3e-64
Identities = 202/655 (30%), Positives = 329/655 (50%), Gaps = 41/655 (6%)
Query: 113 LEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYY 171
+ +QTK ++ + +V R KR W +LE +GP P ++ ++ S++ + + ++ Y
Sbjct: 34 MRNQTKHIEG---ETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKY 90
Query: 172 SIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLI 230
+ G G +F ++ TG+++ T+ +DREQ + + A A P P I
Sbjct: 91 ILTGEGAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFI 146
Query: 231 IKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVP 289
IK++D NDN P FT+ Y T+ E +GT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 147 IKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP 206
Query: 290 PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVN 349
FS+ P TGVI T +DRE + Y + I+ +DM GQ GL ++T I + DVN
Sbjct: 207 ----YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVN 262
Query: 350 DHLPTFTRTSYVTSVEENT-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVT 408
D+ P F + Y V E+ V + ++ D D + A+ Y+I+ G+ G F I T
Sbjct: 263 DNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSIST 320
Query: 409 DAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEG 468
D +T EG+L + KPLNYE+K+ L I N R + + + V D DE
Sbjct: 321 DKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEP 380
Query: 469 PECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRY--KKLTDPTGWVTIDENTGS 526
P + P + + ENA++GT A DP++ ++S +RY + + ID NTG+
Sbjct: 381 PLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGT 439
Query: 527 IKVFRSLDREAETIKNGIYNITVLAS--DQGGRTCTGTLGIILQDVNDNSPFIPKK-TVI 583
I+ + LDRE + YNITV AS D T+GI + DVNDN P + ++ +I
Sbjct: 440 IRTTKVLDRE----ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDII 495
Query: 584 IC---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ-- 638
+C KP I A D D+ +GP F+F L+ V + LK D A + +
Sbjct: 496 VCENSKPGQVIHTISATDKDDFANGPRFNFFLDERL-PVNPNFTLKDNEDNTASILTRRR 554
Query: 639 --NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLG 693
+ Y +PI + D +SS ++L + +C C + T + + G+ G
Sbjct: 555 RFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTG 614
Query: 694 KWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
A++AILL + +L I+ L + K+P +I ++ ++N++ + E G++
Sbjct: 615 --ALIAILLCVLILLAIV-VLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEE 666
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 243 bits (621), Expect = 4e-64
Identities = 182/592 (30%), Positives = 285/592 (48%), Gaps = 42/592 (7%)
Query: 138 APIPCSMLENSLGPFPLFLQQVQ-SDTAQNYTIYYSIRGPGVDQE--PRNLFYVERDTGN 194
AP P M+ENS P P+ + QV+ +D Y++ VD+E PR F ++++ G+
Sbjct: 241 APKPVEMVENSTDPHPIKITQVRWNDPGAQYSL--------VDKEKLPRFPFSIDQE-GD 291
Query: 195 LYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFE 254
+Y T+P+DRE+ +++ A A G PL + +K++D NDN P F + E
Sbjct: 292 IYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQE 351
Query: 255 NCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMHPTTGVITTTSSQLD 312
N R+G ++G + A D+DE +T ++ L Y I+ Q P P LF + G++ L
Sbjct: 352 NERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLK 411
Query: 313 RELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY--VTSVEENTVD 370
++ +Y L I+V D D +T IN+ D+ND +P F ++ Y +T E+ +
Sbjct: 412 KQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIG 466
Query: 371 VEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQ 430
IL + D D T + + Y I+KG+ G + TD TN G + + KPL++E
Sbjct: 467 STILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAV 526
Query: 431 MILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTS 490
+ N P +A S A T+ V D +E P+ + + ++ E+ +GT
Sbjct: 527 SNIVFKAENPEPLVFGVK-YNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKV 585
Query: 491 NGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL 550
A DPE I Y D GW+ ID TG I LDREA Y + V+
Sbjct: 586 GNVTAKDPE---GLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREA----GSPYRVQVV 638
Query: 551 ASDQGGRTCTGT--LGIILQDVNDNSPFIPK--KTVIICKPTMSSAEIV--AVDPDEPI- 603
A++ GG + + +IL DVNDN P + K + C P + ++ A D D+ +
Sbjct: 639 ATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLF 698
Query: 604 HGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQN-DPPFGSYVVPITVRD--RLGMSS 660
GP F FSL S + +Q W + IN T ARLS ++ + YVV I + D R +
Sbjct: 699 RGPHFTFSLGSGS--LQNDWEVSKINGTHARLSTRHTEFEEREYVVLIRINDGGRPPLEG 756
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
+ SL VT C C+ E C + G V + +L LL I ++ ++F
Sbjct: 757 IVSLPVTFCSCV-EGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGIILAVVF 807
Score = 120 bits (302), Expect = 4e-27
Identities = 118/447 (26%), Positives = 200/447 (44%), Gaps = 50/447 (11%)
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
E N+F +ER+ G LY R +DRE + + A +G E P+P+ IK++D NDN
Sbjct: 65 ETDNIFVIERE-GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNR 123
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMH 298
P F + Y ++ +N R G V ATD D+P T + +L Y I+ Q+P + F ++
Sbjct: 124 PTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQIN 183
Query: 299 PTTGVITTT---SSQLDRELIDKYQLKIKVQDMDGQYFG--LQTTSTCIINIDDVNDHLP 353
TG I+ T S +L+ Y L I V+DM GQ TTS II +++
Sbjct: 184 NKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENI----- 238
Query: 354 TFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTN 413
+ + EN+ D +++T V + A Y+++ + F D
Sbjct: 239 --WKAPKPVEMVENSTDPHPIKIT-----QVRWNDPGAQYSLVDKEKLPRFPFSID---Q 288
Query: 414 EGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVED-QDEGPECN 472
EG + V +PL+ EEK + +++ + + V V+D D P C
Sbjct: 289 EGDIYVTQPLDREEKDAYVFY-------AVAKDEYGKPLSYPLEIHVKVKDINDNPPTCP 341
Query: 473 PPIQTVRMKENAEVGTTSNGYKAY--DPETRSSSGIRYKKLTDP-----TGWVTIDENTG 525
P+ ++EN +G + A+ D E ++S + Y+ + G I G
Sbjct: 342 SPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAG 401
Query: 526 SIKVFRSLDREAETIKNGIYNITVLASDQGGRT-CTGTLGIILQDVNDNSPFIPKK---T 581
+++ + ++ +T + YN+T+ SD+ +T C + +I D+ND P K
Sbjct: 402 MLQLAKQSLKKQDTPQ---YNLTIEVSDKDFKTLCFVQINVI--DINDQIPIFEKSDYGN 456
Query: 582 VIICKPTMSSAEIV---AVDPDEPIHG 605
+ + + T + I+ A D DEP G
Sbjct: 457 LTLAEDTNIGSTILTIQATDADEPFTG 483
>gi|221316593 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 243 bits (621), Expect = 4e-64
Identities = 182/592 (30%), Positives = 285/592 (48%), Gaps = 42/592 (7%)
Query: 138 APIPCSMLENSLGPFPLFLQQVQ-SDTAQNYTIYYSIRGPGVDQE--PRNLFYVERDTGN 194
AP P M+ENS P P+ + QV+ +D Y++ VD+E PR F ++++ G+
Sbjct: 241 APKPVEMVENSTDPHPIKITQVRWNDPGAQYSL--------VDKEKLPRFPFSIDQE-GD 291
Query: 195 LYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFE 254
+Y T+P+DRE+ +++ A A G PL + +K++D NDN P F + E
Sbjct: 292 IYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQE 351
Query: 255 NCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMHPTTGVITTTSSQLD 312
N R+G ++G + A D+DE +T ++ L Y I+ Q P P LF + G++ L
Sbjct: 352 NERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLK 411
Query: 313 RELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY--VTSVEENTVD 370
++ +Y L I+V D D +T IN+ D+ND +P F ++ Y +T E+ +
Sbjct: 412 KQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIG 466
Query: 371 VEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQ 430
IL + D D T + + Y I+KG+ G + TD TN G + + KPL++E
Sbjct: 467 STILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAV 526
Query: 431 MILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTS 490
+ N P +A S A T+ V D +E P+ + + ++ E+ +GT
Sbjct: 527 SNIVFKAENPEPLVFGVK-YNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKV 585
Query: 491 NGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL 550
A DPE I Y D GW+ ID TG I LDREA Y + V+
Sbjct: 586 GNVTAKDPE---GLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREA----GSPYRVQVV 638
Query: 551 ASDQGGRTCTGT--LGIILQDVNDNSPFIPK--KTVIICKPTMSSAEIV--AVDPDEPI- 603
A++ GG + + +IL DVNDN P + K + C P + ++ A D D+ +
Sbjct: 639 ATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLF 698
Query: 604 HGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQN-DPPFGSYVVPITVRD--RLGMSS 660
GP F FSL S + +Q W + IN T ARLS ++ + YVV I + D R +
Sbjct: 699 RGPHFTFSLGSGS--LQNDWEVSKINGTHARLSTRHTEFEEREYVVLIRINDGGRPPLEG 756
Query: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
+ SL VT C C+ E C + G V + +L LL I ++ ++F
Sbjct: 757 IVSLPVTFCSCV-EGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGIILAVVF 807
Score = 120 bits (302), Expect = 4e-27
Identities = 118/447 (26%), Positives = 200/447 (44%), Gaps = 50/447 (11%)
Query: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
E N+F +ER+ G LY R +DRE + + A +G E P+P+ IK++D NDN
Sbjct: 65 ETDNIFVIERE-GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNR 123
Query: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMH 298
P F + Y ++ +N R G V ATD D+P T + +L Y I+ Q+P + F ++
Sbjct: 124 PTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQIN 183
Query: 299 PTTGVITTT---SSQLDRELIDKYQLKIKVQDMDGQYFG--LQTTSTCIINIDDVNDHLP 353
TG I+ T S +L+ Y L I V+DM GQ TTS II +++
Sbjct: 184 NKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENI----- 238
Query: 354 TFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTN 413
+ + EN+ D +++T V + A Y+++ + F D
Sbjct: 239 --WKAPKPVEMVENSTDPHPIKIT-----QVRWNDPGAQYSLVDKEKLPRFPFSID---Q 288
Query: 414 EGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVED-QDEGPECN 472
EG + V +PL+ EEK + +++ + + V V+D D P C
Sbjct: 289 EGDIYVTQPLDREEKDAYVFY-------AVAKDEYGKPLSYPLEIHVKVKDINDNPPTCP 341
Query: 473 PPIQTVRMKENAEVGTTSNGYKAY--DPETRSSSGIRYKKLTDP-----TGWVTIDENTG 525
P+ ++EN +G + A+ D E ++S + Y+ + G I G
Sbjct: 342 SPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAG 401
Query: 526 SIKVFRSLDREAETIKNGIYNITVLASDQGGRT-CTGTLGIILQDVNDNSPFIPKK---T 581
+++ + ++ +T + YN+T+ SD+ +T C + +I D+ND P K
Sbjct: 402 MLQLAKQSLKKQDTPQ---YNLTIEVSDKDFKTLCFVQINVI--DINDQIPIFEKSDYGN 456
Query: 582 VIICKPTMSSAEIV---AVDPDEPIHG 605
+ + + T + I+ A D DEP G
Sbjct: 457 LTLAEDTNIGSTILTIQATDADEPFTG 483
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 237 bits (605), Expect = 3e-62
Identities = 198/643 (30%), Positives = 314/643 (48%), Gaps = 39/643 (6%)
Query: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT-AQNYTIYYSIRGPGVDQEPRNLF 186
+VL+R+KR W ++E GP P+ + ++ SD + + I Y + G G +F
Sbjct: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIF 101
Query: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIFTE 245
++ +GN++ T+ +DRE+ + ++A A D P E P I+K++D NDN P F
Sbjct: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
Query: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
ETY + E VGT+V QV A+D D+P ++ +L YSI+ P FS+ TG+I
Sbjct: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGII 217
Query: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364
T +DRE ++Y + I+ +DM G GL T+ I + DVND+ P F ++ Y SV
Sbjct: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSV 277
Query: 365 EENTV-DVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
E V E+ RV +D D+ N Y I+ G+ +F+I TD +T EGV+ + KP+
Sbjct: 278 SEAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
Query: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
++E K+ L++ N + S T TV ++VED DE P P ++EN
Sbjct: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
Query: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
A GT A DP+ ++S IRY + TD + TI+ G IK + LDRE +
Sbjct: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
Query: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIICK----PTMSSAEI 594
NITV A++ R + + ++ DVNDN+P F IC+ +S+ I
Sbjct: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
Query: 595 VAV---DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTA---ARLSYQNDPPFGSYVV 648
V + D D+ +GP F FSL ++TA AR + Y++
Sbjct: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
Query: 649 PITVRDR--LGMSSVTSLDVTLCDC-ITENDCTHRVDPRIGGGGVQLGKWAILAILLGIA 705
PI + D MSS +L + +C C + + + I G+ G A++AIL I
Sbjct: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG--ALIAILACIV 628
Query: 706 LLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
+L I+ V + V ++ ++N+I + E G++
Sbjct: 629 ILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEE 671
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 233 bits (593), Expect = 7e-61
Identities = 197/654 (30%), Positives = 316/654 (48%), Gaps = 42/654 (6%)
Query: 116 QTKVLKKRHTKE--KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYS 172
Q ++L R + K+L R KR W +LE G ++ ++ SD + + ++ Y
Sbjct: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Query: 173 IRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLII 231
+ G G LF ++ TG+++ TR +DRE+ + + A A P P +I
Sbjct: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
Query: 232 KIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPP 290
KI D NDN P F EE YT ++ E VGT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
Query: 291 SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVND 350
FS+ P TG+I T ++RE ++YQ+ I+ +DM GQ GL T+T I + DVND
Sbjct: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
Query: 351 HLPTFTR-TSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTD 409
+ P F + T ++ +E + V I V D D N Y I+ G+ F IVT+
Sbjct: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
Query: 410 AKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGP 469
T EG++ V KPL+YE ++ L++ N R T V +++ED DE P
Sbjct: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
Query: 470 ECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSI 527
+ + E+ EVGT A DP++ SS IR+ + TD I GS+
Sbjct: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSL 441
Query: 528 KVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVII 584
+ LDRE + +N+TV+A++ T + + ++ DVNDN+P F +
Sbjct: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
Query: 585 C---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ--- 638
C +P I AVD D+P+ G F FSL + V + ++ D AR+ +
Sbjct: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSL----AAVNPNFTVQDNEDNTARILTRKNG 553
Query: 639 -NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITE-NDCTHRVDPRIGGGGVQLGK 694
N +Y++P+ + D SS +L + +C C ++ N + + + G+ G
Sbjct: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG- 612
Query: 695 WAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
A++AILL I +L I+ K+P ++ + + N++ N E G++
Sbjct: 613 -ALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE 665
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 230 bits (586), Expect = 5e-60
Identities = 196/637 (30%), Positives = 311/637 (48%), Gaps = 37/637 (5%)
Query: 131 RRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLFYVE 189
+R KR W +LE G PL++ ++ SD + + +I Y + G G +F ++
Sbjct: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
Query: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETY 248
TG+++ + +DRE+ + + A A P P IIKI+D NDN P F + Y
Sbjct: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
Query: 249 TFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTT 307
T+ E VGT+V QV ATD D+P ++ R+ YSI+ P FS+ TGVI T
Sbjct: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
Query: 308 SSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEEN 367
+DRE + Y++ I+ +DM GQ GL T+T I + DVND+ P F + Y SV E+
Sbjct: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
Query: 368 T-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426
+ + RV KDL N YTI+ G+ F I TD G++ V KPL++E
Sbjct: 287 APISSTVGRVFA--KDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFE 344
Query: 427 EKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEV 486
K+ L++ N R + T TV ++VED DE P P V + E+ +
Sbjct: 345 SKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAI 404
Query: 487 GTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGI 544
GTT A DP+ ++S IRY + +DP + +D TG++ R LDRE +
Sbjct: 405 GTTIQIISAKDPDVTNNS-IRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSW 459
Query: 545 YNITVLASDQGGRTCTGTLGIILQ--DVNDNSPFIPK-KTVIICKPTMSS---AEIVAVD 598
+NITVLA + + G++ + ++ DVNDN+P P+ +C+ + + AVD
Sbjct: 460 HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVD 519
Query: 599 PDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL----SYQNDPPFGSYVVPITVRD 654
D+P +G F +SL + + ++ D AR+ S + +PI + D
Sbjct: 520 QDDPRNGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIAD 578
Query: 655 --RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
+ +SS +L + +C C ++ P V L + A++AIL I +L +L
Sbjct: 579 SGQPVLSSTGTLTIQVCSC-DDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLL-VLV 636
Query: 713 TLVCGASGTSKQPKVIPD-DLAQQNLIVSNTEAPGDD 748
L+ KQP +I D + +N++ + E G++
Sbjct: 637 LLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEE 673
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 225 bits (574), Expect = 1e-58
Identities = 193/649 (29%), Positives = 312/649 (48%), Gaps = 35/649 (5%)
Query: 118 KVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGP 176
+ L+ + L R+KR W +LE G ++ ++ SD + + ++ Y + G
Sbjct: 36 RALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGD 95
Query: 177 GVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIED 235
G +LF + +TG++ T+ +DRE+ + + A A P P IIKI D
Sbjct: 96 GAG----DLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHD 151
Query: 236 ENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTL 294
NDN PIFT+E YT T+ E VGT V QV ATD D+P ++ ++ YSI+ P
Sbjct: 152 INDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP----Y 207
Query: 295 FSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPT 354
FS+ TG+I T +DRE ++YQ+ I+ +DM GQ GL T+T I + DVND+ P
Sbjct: 208 FSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPR 267
Query: 355 FTRTSY-VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTN 413
F +++Y + E + I R+ D D+ A Y+I G F ++TD +T
Sbjct: 268 FPQSTYQFKTPESSPPGTPIGRIKASDADVGENA--EIEYSITDGEGLDMFDVITDQETQ 325
Query: 414 EGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNP 473
EG++ V K L++E+K+ L++ N R +ATV + VED DE P +
Sbjct: 326 EGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSK 385
Query: 474 PIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFR 531
++++E+A++ TT A DP+ + + ++Y + TD ID GSI +
Sbjct: 386 LAYILQIREDAQINTTIGSVTAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSK 444
Query: 532 SLDREAETIKNGIYNITVLASDQGG--RTCTGTLGIILQDVNDNSP-FIPKKTVIICKPT 588
LDRE +NITV+A++ ++ L I + DVNDN+P F +C+
Sbjct: 445 LLDRETLL----WHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKA 500
Query: 589 MSSAEIV---AVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQND---PP 642
+ I AVD D+P G F FSL + ++TA L+ +N
Sbjct: 501 KADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHE 560
Query: 643 FGSYVVPITVRDR--LGMSSVTSLDVTLCDCITE-NDCTHRVDPRIGGGGVQLGKWAILA 699
+Y++P+ + D SS ++ V +C C N + + I G+ G A++A
Sbjct: 561 MSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTG--ALVA 618
Query: 700 ILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
ILL I +L + K+P +I + + N++ N E G++
Sbjct: 619 ILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEE 667
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 223 bits (567), Expect = 8e-58
Identities = 187/642 (29%), Positives = 317/642 (49%), Gaps = 37/642 (5%)
Query: 126 KEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRN 184
++++L R+KR W +LE GP P+ + ++ +D + I Y + G G
Sbjct: 52 EQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAG----T 107
Query: 185 LFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIF 243
+F + TG+++ + +DRE+ + + A A + P E P IIK++D NDN P F
Sbjct: 108 IFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEF 167
Query: 244 TEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTG 302
Y T+ E +GT+V V ATD D+P ++ +L YSI+ P FS+ P T
Sbjct: 168 LNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP----YFSIEPETA 223
Query: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
+I T +DRE ++Y + I+ +DM G GL T+T + + DVND+ P F ++ Y
Sbjct: 224 IIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHF 283
Query: 363 SVEENTV-DVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVK 421
SV E+ V I RV D+D+ A +++Y I+ G+ F+I +DA+ +G++ + K
Sbjct: 284 SVPEDVVLGTAIGRVKANDQDIGENA--QSSYDIIDGDGTALFEITSDAQAQDGIIRLRK 341
Query: 422 PLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMK 481
PL++E K+ L++ N R + TATV + VED DE P + P + +
Sbjct: 342 PLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVH 401
Query: 482 ENAEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAET 539
ENA + + A DP+ +SS IR+ + TD I+ + G I + LDRE
Sbjct: 402 ENAALNSVIGQVTARDPDI-TSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSV 460
Query: 540 IKNGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIIC---KPTMSSAE 593
+NIT++A++ + + + ++ DVNDN+P F + +C KP
Sbjct: 461 ----WHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQT 516
Query: 594 IVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQND---PPFGSYVVPI 650
+ A+D D+P +G F +SL K +++ + L+ N Y++PI
Sbjct: 517 VSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPI 576
Query: 651 TVRD--RLGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLGKWAILAILLGIALL 707
+ D +SS ++L + +C C + + V+ + G+ +G A++AIL I LL
Sbjct: 577 IISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMG--ALIAILACIILL 634
Query: 708 FCILFTLVCGASGTSKQPKVIPDDL-AQQNLIVSNTEAPGDD 748
I+ V +P +I DD ++N+I + E G++
Sbjct: 635 LVIVVLFVT-LRRHKNEPLIIKDDEDVRENIIRYDDEGGGEE 675
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 214 bits (545), Expect = 3e-55
Identities = 181/648 (27%), Positives = 310/648 (47%), Gaps = 53/648 (8%)
Query: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLF 186
K+LRR KR W +LE G ++ ++ +D + + + Y + G G +LF
Sbjct: 46 KMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG----SLF 101
Query: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATT-PDGYTPELPLPLIIKIEDENDNYPIFTE 245
++ +TG+++ + +DRE+ + + A A G E IIKI D NDN P FT+
Sbjct: 102 VIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK 161
Query: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
+ YT ++ E VGT+V QV ATD D+ + ++ ++ YSI+ P FS+ P +G+I
Sbjct: 162 DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDPESGII 217
Query: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY-VTS 363
T + RE ++YQ+ I+ +DM GQ GL T+T I + DVN++ P F +++Y S
Sbjct: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
Query: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
E + + R+ D D+ A Y+I +G+ F ++TD T EG++ V + L
Sbjct: 278 PESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
Query: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
++E + L++ N P R TA V ++VED DE P + + E+
Sbjct: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
Query: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
+ G+ AYDP+ R++ I+Y + TD I GSI ++LDRE+
Sbjct: 396 VKEGSIIGQVTAYDPDARNNL-IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES---- 450
Query: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIIC---KPTMSSAEIV 595
+ +NITV A++ + + + ++ D+ND++P F +C KP +
Sbjct: 451 SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVS 510
Query: 596 AVDPDEPIHGPPF------DFSLESSTSEVQRMWRLKAINDTAARLSYQND----PPFGS 645
+D D+P G F +F+L + + V D A + + D +
Sbjct: 511 VMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDN-------KDNTAGIMTRKDGYSRNKMST 563
Query: 646 YVVPITV--RDRLGMSSVTSLDVTLCDCITEND---CTHRVDPRIGGGGVQLGKWAILAI 700
Y++PI + D SS +L + +C C + + CT + I G+ G A++AI
Sbjct: 564 YLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCT--AEALILSAGLSTG--ALVAI 619
Query: 701 LLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
LL + +L ++ K+P +I D + N++ N E G++
Sbjct: 620 LLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEE 667
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 214 bits (545), Expect = 3e-55
Identities = 188/636 (29%), Positives = 297/636 (46%), Gaps = 35/636 (5%)
Query: 131 RRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNY-TIYYSIRGPGVDQEPRNLFYVE 189
+R KR W +LE +G P ++ ++ SD + T+ Y++ G G +F ++
Sbjct: 50 QRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAG----TVFTID 105
Query: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLIIKIEDENDNYPIFTEETY 248
TG+++ R +DRE+ + + A A + P P IIK++D NDN P F + Y
Sbjct: 106 ETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPY 165
Query: 249 TFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITTT 307
T+ E VG V QV ATD D+P ++ R+ YSI+ P FS+ P TGVI T
Sbjct: 166 VATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP----YFSIDPKTGVIRTA 221
Query: 308 SSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEEN 367
+DRE+ ++YQ+ I+ +DM GQ GL T+ I + DVND+ P F ++ + V E+
Sbjct: 222 LPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPES 281
Query: 368 T-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYE 426
+ + I R+ D D A Y I+ G+ F IVTD T EGV+ + KPL++E
Sbjct: 282 SPIGSAIGRIRAVDPDFGQNAE--IEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFE 339
Query: 427 EKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEV 486
K+ ++ N R S TATV ++V D DE P + P+ T+ + E+ V
Sbjct: 340 TKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPV 399
Query: 487 GTTSNGYKAYDPETRSSSGIRY--KKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGI 544
GT A D + SS +RY +D + TID N G+I LDRE+
Sbjct: 400 GTIIGAVTAQDLDV-GSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES----TAQ 454
Query: 545 YNITVLASDQGGRTCTGTLGIILQ--DVNDNSP--FIPKKTVII--CKPTMSSAEIVAVD 598
YN +++AS T + I++ DVN+ P +P +T + KP + A D
Sbjct: 455 YNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQIVSAAD 514
Query: 599 PDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGS---YVVPITVRDR 655
D G F F L + N+TA + +N Y +P+ + D
Sbjct: 515 RDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDS 574
Query: 656 L--GMSSVTSLDVTLCDCITEND-CTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILF 712
SS ++ + +C C ++ + V+ G+ G A++AILL I +L I+
Sbjct: 575 SYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTG--ALIAILLCIVILLAIVV 632
Query: 713 TLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
V K + + + N+I + E G++
Sbjct: 633 LYVALRRQKKKDTLMTSKEDIRDNVIHYDDEGGGEE 668
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,420,481
Number of Sequences: 37866
Number of extensions: 1536740
Number of successful extensions: 6707
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3449
Number of HSP's gapped (non-prelim): 845
length of query: 847
length of database: 18,247,518
effective HSP length: 111
effective length of query: 736
effective length of database: 14,044,392
effective search space: 10336672512
effective search space used: 10336672512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.