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Search of human proteins with 13435361
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
(894 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 1824 0.0
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 1684 0.0
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 947 0.0
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 895 0.0
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 834 0.0
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 808 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 429 e-120
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 388 e-107
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 380 e-105
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 342 7e-94
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 334 2e-91
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 333 6e-91
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 323 3e-88
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 312 8e-85
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 307 3e-83
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 297 3e-80
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 293 5e-79
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 275 1e-73
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 275 1e-73
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 274 3e-73
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 265 1e-70
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 252 1e-66
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 249 6e-66
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 246 9e-65
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 245 1e-64
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 235 2e-61
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 227 4e-59
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 218 2e-56
gi|16753221 cadherin 22 precursor [Homo sapiens] 218 2e-56
gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 218 3e-56
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 1824 bits (4724), Expect = 0.0
Identities = 894/894 (100%), Positives = 894/894 (100%)
Query: 1 MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS 60
MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS
Sbjct: 1 MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS 60
Query: 61 LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK 120
LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK
Sbjct: 61 LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK 120
Query: 121 KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE 180
KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE
Sbjct: 121 KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE 180
Query: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP 240
PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP
Sbjct: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP 240
Query: 241 YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT 300
YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT
Sbjct: 241 YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT 300
Query: 301 GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV 360
GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV
Sbjct: 301 GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV 360
Query: 361 TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK 420
TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK
Sbjct: 361 TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK 420
Query: 421 PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS 480
PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS
Sbjct: 421 PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS 480
Query: 481 QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV 540
QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV
Sbjct: 481 QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV 540
Query: 541 KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG 600
KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG
Sbjct: 541 KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG 600
Query: 601 PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML 660
PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML
Sbjct: 601 PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML 660
Query: 661 TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV 720
TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV
Sbjct: 661 TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV 720
Query: 721 KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF 780
KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF
Sbjct: 721 KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF 780
Query: 781 EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEH 840
EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEH
Sbjct: 781 EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEH 840
Query: 841 KHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCIKK 894
KHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCIKK
Sbjct: 841 KHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCIKK 894
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 1684 bits (4360), Expect = 0.0
Identities = 829/830 (99%), Positives = 830/830 (100%)
Query: 1 MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS 60
MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS
Sbjct: 1 MALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSAS 60
Query: 61 LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK 120
LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK
Sbjct: 61 LIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPK 120
Query: 121 KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE 180
KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE
Sbjct: 121 KRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKE 180
Query: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP 240
PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP
Sbjct: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAP 240
Query: 241 YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT 300
YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT
Sbjct: 241 YFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDT 300
Query: 301 GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV 360
GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV
Sbjct: 301 GVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYV 360
Query: 361 TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK 420
TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK
Sbjct: 361 TEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVK 420
Query: 421 PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS 480
PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS
Sbjct: 421 PLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQS 480
Query: 481 QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV 540
QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV
Sbjct: 481 QDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFV 540
Query: 541 KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG 600
KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG
Sbjct: 541 KNNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVDPDG 600
Query: 601 PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML 660
PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML
Sbjct: 601 PENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHML 660
Query: 661 TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV 720
TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV
Sbjct: 661 TVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTV 720
Query: 721 KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF 780
KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF
Sbjct: 721 KKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSF 780
Query: 781 EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEK 830
EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGE+
Sbjct: 781 EMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGEE 830
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 947 bits (2447), Expect = 0.0
Identities = 489/904 (54%), Positives = 639/904 (70%), Gaps = 17/904 (1%)
Query: 2 ALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASL 61
A S + C+ LL +L +L DAC+ V L VPS L AE LVG+VNL+EC +A+L
Sbjct: 4 ARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANL 63
Query: 62 IRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKK 121
I SSDP F+ILEDGS+YTT+ ++LSSE++SF+I LS+ + +E+++I V L + K KK
Sbjct: 64 IHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLE-HQTKVLKK 122
Query: 122 RHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEP 181
RHTK+ L+R+KRRWAPIP S++ENSLGPFP +QQ+QSD AQNYTI+YSI GPGVD+EP
Sbjct: 123 RHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEP 182
Query: 182 FNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPY 241
NLFY+E+DTG+++CTR +DRE+YE F + +ATT DGY PE PLPLIIKIED+NDN P
Sbjct: 183 RNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPI 242
Query: 242 FEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTG 301
F FT+ ENCR GT+VG+V ATD DEPDT+HTRLKY I+ Q+P P FS+HP TG
Sbjct: 243 FTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTG 302
Query: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
VITTT+ LDRE D YQL ++V+DM GQ FGL T T I+++D ND+ P+FT TSYVT
Sbjct: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
Query: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
VEEN +DVEILR+ V+D+DL NT + +A Y IL+GNENGNF I TD TNEGVLCVVKP
Sbjct: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
Query: 422 LNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQ 481
LNYE +Q+ILQ+GV+NEA FS+ AS ++ M T TVTV + D DEGPEC+PP++ ++ +
Sbjct: 423 LNYEEKQQMILQIGVVNEAPFSREASPRS-AMSTATVTVNVEDQDEGPECNPPIQTVRMK 481
Query: 482 DGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
+ G GYKA DPE S G+RY+KL D W I+++TG ++ + LDRE++ +K
Sbjct: 482 ENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 542 NNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDG 600
N YNI+V+A D GR+CTGTL + L D ND++P I K+ V IC+ A + VDPD
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
Query: 601 PENGPPFQFFLDNSAS---KNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVAT 657
P +GPPF F L++S S + W ++ + A L + + + Y VPI ++DR G+ +
Sbjct: 602 PIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSV 661
Query: 658 HMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFC-VTA 716
L V +CDC T ++C + R V LG+WAILA++LG LL CILFT C +
Sbjct: 662 TSLDVTLCDCITENDCTHR-VDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 717 KRTVKKCFPEDIAQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIK 775
K P+D+AQQNLIVSNTE PG++ V AN T + ++ V G GIK
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSAN---GFTTQTVGASAQGVCGTVGSGIK 777
Query: 776 T--QQSFEMVKGGY-TLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEK 830
Q++ EMVKGG+ T +S +G G H TL+S + G + D RY Y++W SFTQPRLGEK
Sbjct: 778 NGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEK 837
Query: 831 VYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKT 890
VYLC QDE HKH +DYV +YNYEG+GS+AGSVGCCS+RQEE+GLEFLD+LEPKFRTLA+
Sbjct: 838 VYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEA 897
Query: 891 CIKK 894
C+K+
Sbjct: 898 CMKR 901
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 895 bits (2313), Expect = 0.0
Identities = 460/892 (51%), Positives = 623/892 (69%), Gaps = 20/892 (2%)
Query: 13 CKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASLIRSSDPAFRIL 72
C LL +L++ + +AC+KV L VPS L+A+ ++G+VNLEEC +SA LIRSSDP FR+L
Sbjct: 15 CLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVL 74
Query: 73 EDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKKRHTKDTALKRS 132
DGS+YT + LS +++SF+I+LSD +++ Q+E+ V+L + K K RHT++T L+R+
Sbjct: 75 NDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-HQKKVSKTRHTRETVLRRA 133
Query: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
KRRWAPIP S+ ENSLGPFP +QQ++SDAAQNYT+FYSISG GVDKEP NLFYIE+DTG
Sbjct: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
Query: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
++FCTR +DRE+Y+ F L YA+TADGY+ + PLPL I++ED+NDN P F + F V
Sbjct: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
Query: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPFLDR 312
E+ R GT+VG V ATD DEPDT+HTRLKY ILQQ P P FS+HP TGVITT + +LDR
Sbjct: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDR 313
Query: 313 EKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEI 372
E D Y LIM+V+DM GQ FGL T T I++ D NDN P+F + +Y VEEN +VEI
Sbjct: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEI 373
Query: 373 LRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVIL 432
LR+ ++D+DL NT + + + IL+GNENG+F ISTD TNEGVL VVKPLNYE NRQV L
Sbjct: 374 LRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNL 433
Query: 433 QVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLG 492
++GV NEA F++ T + VTV + D DEGPEC P + ++ ++ G ++ G
Sbjct: 434 EIGVNNEAPFARDIPRVT-ALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKING 492
Query: 493 YKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV 552
YKA DPE +G GLRY+KL D W I++ +G + T K+LDRE + KN YNI+V+A+
Sbjct: 493 YKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAI 552
Query: 553 DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDGPENGPPFQFFL 611
D RSCTGTL V+++D ND+ P+I +E V IC+ + + VDPD P +G PF F L
Sbjct: 553 DKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSL 612
Query: 612 DNSA---SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCS 668
N++ S+ W++ + + A L ++N + Y++PI +KDR G AT +L V +C+C+
Sbjct: 613 PNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECT 672
Query: 669 TPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDI 728
P++CR +ST VILG+WAILA++LG LL +L T C T K FPED+
Sbjct: 673 HPTQCRATSRST-----GVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL 727
Query: 729 AQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIKT--QQSFEMVKG 785
AQQNLI+SNTE PG++ V AN + T+N +S G G+K Q++ EM+KG
Sbjct: 728 AQQNLIISNTEAPGDDRVCSANGFMTQTTNN---SSQGFCGTMGSGMKNGGQETIEMMKG 784
Query: 786 G-YTLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEHKH 842
G TL+S +G G H TL+S + G + D RY Y++W SFTQPRLGEK++ C Q+E+
Sbjct: 785 GNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMP 844
Query: 843 CEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCIKK 894
+DYV +YNYEG+GS AGSVGCCS++QEE+GL+FL++LEPKF TLA+ C K+
Sbjct: 845 SQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR 896
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 834 bits (2154), Expect = 0.0
Identities = 439/840 (52%), Positives = 580/840 (69%), Gaps = 17/840 (2%)
Query: 2 ALASAAPGSIFCKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASL 61
A S + C+ LL +L +L DAC+ V L VPS L AE LVG+VNL+EC +A+L
Sbjct: 4 ARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANL 63
Query: 62 IRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKK 121
I SSDP F+ILEDGS+YTT+ ++LSSE++SF+I LS+ + +E+++I V L + K KK
Sbjct: 64 IHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLE-HQTKVLKK 122
Query: 122 RHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEP 181
RHTK+ L+R+KRRWAPIP S++ENSLGPFP +QQ+QSD AQNYTI+YSI GPGVD+EP
Sbjct: 123 RHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEP 182
Query: 182 FNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPY 241
NLFY+E+DTG+++CTR +DRE+YE F + +ATT DGY PE PLPLIIKIED+NDN P
Sbjct: 183 RNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPI 242
Query: 242 FEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTG 301
F FT+ ENCR GT+VG+V ATD DEPDT+HTRLKY I+ Q+P P FS+HP TG
Sbjct: 243 FTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTG 302
Query: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
VITTT+ LDRE D YQL ++V+DM GQ FGL T T I+++D ND+ P+FT TSYVT
Sbjct: 303 VITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVT 362
Query: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
VEEN +DVEILR+ V+D+DL NT + +A Y IL+GNENGNF I TD TNEGVLCVVKP
Sbjct: 363 SVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKP 422
Query: 422 LNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQ 481
LNYE +Q+ILQ+GV+NEA FS+ AS ++ M T TVTV + D DEGPEC+PP++ ++ +
Sbjct: 423 LNYEEKQQMILQIGVVNEAPFSREASPRS-AMSTATVTVNVEDQDEGPECNPPIQTVRMK 481
Query: 482 DGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
+ G GYKA DPE S G+RY+KL D W I+++TG ++ + LDRE++ +K
Sbjct: 482 ENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 542 NNQYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDG 600
N YNI+V+A D GR+CTGTL + L D ND++P I K+ V IC+ A + VDPD
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
Query: 601 PENGPPFQFFLDNSAS---KNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVAT 657
P +GPPF F L++S S + W ++ + A L + + + Y VPI ++DR G+ +
Sbjct: 602 PIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSV 661
Query: 658 HMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFC-VTA 716
L V +CDC T ++C + R V LG+WAILA++LG LL CILFT C +
Sbjct: 662 TSLDVTLCDCITENDCTHR-VDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 717 KRTVKKCFPEDIAQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIK 775
K P+D+AQQNLIVSNTE PG++ V AN T + ++ V G GIK
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSAN---GFTTQTVGASAQGVCGTVGSGIK 777
Query: 776 T--QQSFEMVKGGY-TLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEK 830
Q++ EMVKGG+ T +S +G G H TL+S + G + D RY Y++W SFTQPRLGE+
Sbjct: 778 NGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 837
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 808 bits (2087), Expect = 0.0
Identities = 421/828 (50%), Positives = 570/828 (68%), Gaps = 20/828 (2%)
Query: 13 CKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASLIRSSDPAFRIL 72
C LL +L++ + +AC+KV L VPS L+A+ ++G+VNLEEC +SA LIRSSDP FR+L
Sbjct: 15 CLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVL 74
Query: 73 EDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKKRHTKDTALKRS 132
DGS+YT + LS +++SF+I+LSD +++ Q+E+ V+L + K K RHT++T L+R+
Sbjct: 75 NDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-HQKKVSKTRHTRETVLRRA 133
Query: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
KRRWAPIP S+ ENSLGPFP +QQ++SDAAQNYT+FYSISG GVDKEP NLFYIE+DTG
Sbjct: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
Query: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
++FCTR +DRE+Y+ F L YA+TADGY+ + PLPL I++ED+NDN P F + F V
Sbjct: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
Query: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPFLDR 312
E+ R GT+VG V ATD DEPDT+HTRLKY ILQQ P P FS+HP TGVITT + +LDR
Sbjct: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDR 313
Query: 313 EKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEI 372
E D Y LIM+V+DM GQ FGL T T I++ D NDN P+F + +Y VEEN +VEI
Sbjct: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEI 373
Query: 373 LRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVIL 432
LR+ ++D+DL NT + + + IL+GNENG+F ISTD TNEGVL VVKPLNYE NRQV L
Sbjct: 374 LRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNL 433
Query: 433 QVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLG 492
++GV NEA F++ T + VTV + D DEGPEC P + ++ ++ G ++ G
Sbjct: 434 EIGVNNEAPFARDIPRVT-ALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKING 492
Query: 493 YKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV 552
YKA DPE +G GLRY+KL D W I++ +G + T K+LDRE + KN YNI+V+A+
Sbjct: 493 YKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAI 552
Query: 553 DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDGPENGPPFQFFL 611
D RSCTGTL V+++D ND+ P+I +E V IC+ + + VDPD P +G PF F L
Sbjct: 553 DKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSL 612
Query: 612 DNSA---SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCS 668
N++ S+ W++ + + A L ++N + Y++PI +KDR G AT +L V +C+C+
Sbjct: 613 PNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECT 672
Query: 669 TPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDI 728
P++CR +ST VILG+WAILA++LG LL +L T C T K FPED+
Sbjct: 673 HPTQCRATSRST-----GVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL 727
Query: 729 AQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIKT--QQSFEMVKG 785
AQQNLI+SNTE PG++ V AN + T+N +S G G+K Q++ EM+KG
Sbjct: 728 AQQNLIISNTEAPGDDRVCSANGFMTQTTNN---SSQGFCGTMGSGMKNGGQETIEMMKG 784
Query: 786 G-YTLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEK 830
G TL+S +G G H TL+S + G + D RY Y++W SFTQPRLGE+
Sbjct: 785 GNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 832
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 429 bits (1103), Expect = e-120
Identities = 267/717 (37%), Positives = 392/717 (54%), Gaps = 44/717 (6%)
Query: 64 SSDPA-FRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKS---- 118
SS+PA F++ EDG +Y LSSE F I+ D + +E+ ++ V LS + +
Sbjct: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
Query: 119 -----------PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYT 167
P++ L+R KR W P +L ENS GPFPQ + +I+SD +N +
Sbjct: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
Query: 168 IFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLP 227
+ YS++GPG D+ P +F I +G + T+ +DRE+ +F L +A +G E P+
Sbjct: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
Query: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQI 287
++I + D NDN P F H+V TVPE + GT V VTA D D+P+ L+ L+Y+I+ Q
Sbjct: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
Query: 288 PD--HPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQP-FGLFNTGTITISL 344
P P F+I+ +TG I T LDREK Y LI++ DM G P +GL NT T I++
Sbjct: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
Query: 345 EDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFI 404
D NDNPP FT ++ EV ENR+D+ + + V D+D P+TP AVY+I G+ G F
Sbjct: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
Query: 405 ISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIID 464
I TDPN+N+G++ VVKP+++E NR +L V N+ +K Q P T TV+V +ID
Sbjct: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGI--QHPPQSTATVSVTVID 490
Query: 465 SDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHT 524
+E P P K+I+ ++G AG L + A DP+ + +RY KL D NW +I+
Sbjct: 491 VNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN 550
Query: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQI-DKEV 581
G + T+ VLDRES VKNN YN + +A D S TGTL ++L D ND+APQ+ +E
Sbjct: 551 GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEA 610
Query: 582 TICQNNEDFAV-LKPVDPDGPENGPPFQFFLDNS---ASKNWNIEEKDGKTAILRQR-QN 636
C+ + ++ + +D D N PF F L S +NW I +G A L + +
Sbjct: 611 ETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKF 670
Query: 637 LDYNYYSVPIQIKDRHGLVATH--MLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAI 694
L+ Y VPI I D ++ +L V+VC C + +C D+ LG AI
Sbjct: 671 LEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIV-----GAGLGTGAI 725
Query: 695 LAMVLGSVLLLCILFTCFCVTAKRTVKK-------CFPEDIAQQNLIVSNTEGPGEE 744
+A++L +++L IL F V KR K+ PED + N++ + EG GEE
Sbjct: 726 IAILL-CIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
Score = 30.4 bits (67), Expect = 7.7
Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 845 DYVCSYNYEGKGSLAGSVGCCSDRQE--EEGLEFLDHLEPKFRTLA 888
D + ++YEG GS AGS+ + E+ ++L+ P+F+ LA
Sbjct: 853 DSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLA 898
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 388 bits (996), Expect = e-107
Identities = 257/752 (34%), Positives = 394/752 (52%), Gaps = 57/752 (7%)
Query: 41 LQAETLVGKVNLEECLKS-ASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDG 99
L+ E L+ +V C+ + + ++ F++ DG+++ T +L + SE+ +F++ D
Sbjct: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
Query: 100 QRREQQEIKVVLSARENKSPKKRHT----------------KDT-----------ALKRS 132
Q E+ + V L + SP H KDT L+R
Sbjct: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
Query: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
KR W P ++ ENS GPFPQ + +I+SD + I YSI+G G D+ P +F I+ +G
Sbjct: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
Query: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
++ TR +DRE++ + L +A +G E P+ L I + D NDN P F ++V +V
Sbjct: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
Query: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTGVITTTTPFL 310
E + GT V VTA D D+ T + ++Y+I+ Q P P F+I+ +TG I T L
Sbjct: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
Query: 311 DREKCDTYQLIMEVRDM-GGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRID 369
DREK Y +I++ DM G +GL NT T I++ D NDNPP FT +++ EV ENR++
Sbjct: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
Query: 370 VEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQ 429
+ + V D+D P++P+ AVY+I+ G+ +G+F + TDP TNEG++ VVK ++YE+NR
Sbjct: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
Query: 430 VILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQE 489
+L V V N+A A+ Q T VT+ I+D +E P K+I+ ++G P G
Sbjct: 468 FMLTVMVSNQAPL--ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTV 525
Query: 490 LLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISV 549
L + A+DP+ + +RY KL D +W IN G + T VLDRES + KNN Y +
Sbjct: 526 LTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATF 585
Query: 550 VAVD--AVGRSCTGTLVVHLDDYNDHAPQ-IDKEVTICQN-NEDFAVLKPVDPDGPENGP 605
+A D S TGTL ++L D ND+AP+ + KE IC+ N + + D D N
Sbjct: 586 LAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIG 645
Query: 606 PFQF---FLDNSASKNWNIEEKDGKTAILRQR-QNLDYNYYSVPIQIKDRHG--LVATHM 659
P+ F F+ + KNW I +G A L R L+ Y VPI + D L T +
Sbjct: 646 PYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSI 705
Query: 660 LTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRT 719
+ V+VC C +C +T LG AI+A+++ +L+L + F + KR
Sbjct: 706 IKVKVCPCDDNGDC-----TTIGAVAAAGLGTGAIVAILI-CILILLTMVLLFVMWMKRR 759
Query: 720 VKK-------CFPEDIAQQNLIVSNTEGPGEE 744
K+ PED + N++ + EG GEE
Sbjct: 760 EKERHTKQLLIDPEDDVRDNILKYDEEGGGEE 791
Score = 31.2 bits (69), Expect = 4.5
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 845 DYVCSYNYEGKGSLAGSVGCC-SDRQEEEGLEFLDHLEPKFRTLA 888
D + ++YEG GS AGSV S ++ ++L+ P+F+ LA
Sbjct: 863 DSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLA 907
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 380 bits (976), Expect = e-105
Identities = 261/777 (33%), Positives = 389/777 (50%), Gaps = 56/777 (7%)
Query: 8 PGSIFCKQLLFSLLVLTLLC----------DACQKVYLRVPSHLQAETLVGKVNLEECL- 56
P S LL L V + LC DA + HL+ ++G+VN E+C
Sbjct: 3 PWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTG 62
Query: 57 KSASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSAREN 116
+ + S D F++ DG I L + + F ++ D R+ KV L+ +
Sbjct: 63 RQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFST-KVTLNTVGH 121
Query: 117 KSPKKRHTKDTA---------------LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSD 161
H + L+R KR W P S EN GPFP+++ QI+S+
Sbjct: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
Query: 162 AAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYA 221
+ +FYSI+G G D P +F IE++TG + T +DRE+ + L+ +A +++G A
Sbjct: 182 KDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA 241
Query: 222 PEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEP-DTLHTRLK 280
E P+ ++I + D NDN P F V +V E GTSV +VTATD D+ +T + +
Sbjct: 242 VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIA 301
Query: 281 YKILQQIPDHP--KHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Y IL Q P+ P F+I+ +TGVI+ T LDRE TY L+++ D+ G+ GL T
Sbjct: 302 YTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTA 359
Query: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
T I++ D NDNPP F T+Y +V EN +V I +KV D D PNTP +AVY IL +
Sbjct: 360 TAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL-ND 418
Query: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTV 458
+ G F+++T+P N+G+L K L++E +Q IL V V N F + T T TV
Sbjct: 419 DGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSL-----TTSTATV 473
Query: 459 TVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
TV ++D +E P PP K ++ + F GQE+ Y A +P+ + + Y+ D NW
Sbjct: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
Query: 519 EINQHTGDLRTLKVLDRES-KFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAP 575
EIN TG + T LDRE + VKN+ Y ++A D + + TGTL++ L D ND+AP
Sbjct: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
Query: 576 QID-KEVTICQNNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKD--GKTAILR 632
+ + + C+ N V+ +D D P N PF L + AS NW I+ D ++ IL+
Sbjct: 594 IPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILK 653
Query: 633 QRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDC-STPSECRMKDKSTRDVRPNVILGR 691
+ L+ Y + +++ D L V VCDC CR ++ ILG
Sbjct: 654 PKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILG- 712
Query: 692 WAILAMVLGSVLLLCILFTCFCVTAKR--TVKKCF--PEDIAQQNLIVSNTEGPGEE 744
+LG +L L IL + +R VK+ PED + N+ + EG GEE
Sbjct: 713 ------ILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 342 bits (878), Expect = 7e-94
Identities = 259/826 (31%), Positives = 389/826 (47%), Gaps = 73/826 (8%)
Query: 124 TKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFN 183
TK ++R KR W A+ E + +I+SD N I Y ISG G+D+ P+
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFE 243
+F I TG+I T +DRE F +Y A + G E PL L +K+ D NDNAP F
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 244 HRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVI 303
V ++ EN + T V K+ ATD DE + L++++ YKI+ Q P F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 304 TTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV 363
T + FLDRE+ Y L++ D G GL + I + D NDN P+ +TSY +
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 364 EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
EEN + E++R++ D D T + A Y IL GN+ F I TDP TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
YE + L +GV N+A F + +SQ M T V ++++D EGP HP ++G
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQF-QMHPTPVRIQVVDVREGPAFHPSTMAFSVREG 397
Query: 484 FPAGQELLG-----YKALDPEISS-GEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRES 537
G LL Y A+D + + +RY D +W +I+ TG+++ + D++S
Sbjct: 398 I-KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS 456
Query: 538 KFVKNNQYNISVVAV-DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKP 595
K++ N Y ++A+ D G++ TGT+ + + D ND+ P I E TIC ++ +VL
Sbjct: 457 KYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP--SVLIS 514
Query: 596 VDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRH 652
V+ G PF F + + + W++ + +AIL +Q L +Y +PI +KD +
Sbjct: 515 VNEH--SYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 653 GLVA--THMLTVRVCDCSTPSECRMKDKS---TRDVR--------------PNVILGRWA 693
M+ + CDC C + T D+ NV LG
Sbjct: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632
Query: 694 ILAMVLGSVLLL---CILFTCFCVTAKRTVKKCFPEDIAQQNLIVS----------NTEG 740
I MVLG +LL+ +L C C K+ PE + + V EG
Sbjct: 633 IGMMVLGILLLILAPLLLLLCCC-------KQRQPEGLGTRFAPVPEGGEGVMQSWRIEG 685
Query: 741 PGEEVTE-ANIRLPMQTSNICD----------TSMSVGTVGG--QGIKTQQSFEMVKGGY 787
E + +NI PM SN D T + GTV G G++ G
Sbjct: 686 AHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVG-- 743
Query: 788 TLDSNKGGGHQTLESVKGVGQGDTGRYAYTDW-QSFTQPRLGEKVYLCGQDEEHKHCEDY 846
L + G + G YA D +F EK Y ++E + D
Sbjct: 744 -LMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDC 802
Query: 847 VCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCI 892
+ Y++EG GS GS+GCCS ++ ++ L+PKFRTLA+ C+
Sbjct: 803 LLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICL 848
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 334 bits (856), Expect = 2e-91
Identities = 220/652 (33%), Positives = 331/652 (50%), Gaps = 40/652 (6%)
Query: 115 ENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISG 174
+ ++P K L+R KR W P S+ EN GPFPQ + Q++S+ ++ IFYSI+G
Sbjct: 88 KERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITG 147
Query: 175 PGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIED 234
PG D P +F +EK+TG + + +DRE+ ++ L+G+A + +G + E P+ + I + D
Sbjct: 148 PGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTD 207
Query: 235 DNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTR---LKYKILQQIPDHP 291
ND+ P F +V E GTSV +VTAT DE D ++T + Y I Q P P
Sbjct: 208 QNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTAT--DEDDAIYTYNGVVAYSIHSQEPKDP 265
Query: 292 KH--FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDEND 349
F+IH TG I+ + LDREK Y L ++ DM G G T + + D ND
Sbjct: 266 HDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDAND 323
Query: 350 NPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDP 409
N P F Y V EN + E+ R+ V D D PN+P +A Y I+ G++ +F I+T P
Sbjct: 324 NAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHP 383
Query: 410 NTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGP 469
+N+G+L K L++E Q L V V NEA F + PT T T+ V + D +E P
Sbjct: 384 ESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPF----VLKLPT-STATIVVHVEDVNEAP 438
Query: 470 ECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRT 529
PP KV++ Q+G P G+ + Y A DP+ + + Y+ L D W ++ +G +
Sbjct: 439 VFVPPSKVVEVQEGIPTGEPVCVYTAEDPD-KENQKISYRILRDPAGWLAMDPDSGQVTA 497
Query: 530 LKVLDRE-SKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQID-KEVTICQ 585
+ LDRE +FV+NN Y + V+A+D + + TGTL++ L D NDH P + +++TIC
Sbjct: 498 VGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICN 557
Query: 586 NNEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIE-EKDGKTAILRQRQNLDYNYYSV 644
+ VL D D + PFQ L + + W E ++G T +L ++ L + Y V
Sbjct: 558 QSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDV 617
Query: 645 PIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRW--AILAMVLGSV 702
+ + D ++ VCDC E G W + VLG+V
Sbjct: 618 HLSLSDHGNKEQLTVIRATVCDCHGHVE--------------TCPGPWKGGFILPVLGAV 663
Query: 703 --LLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEANI 750
LL +L V KR +K+ PED + N+ EG GEE + +I
Sbjct: 664 LALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDI 715
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 333 bits (853), Expect = 6e-91
Identities = 254/838 (30%), Positives = 386/838 (46%), Gaps = 78/838 (9%)
Query: 124 TKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFN 183
TK ++R KR W A+ E + +I+SD N I Y ISG G+D+ P+
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFE 243
+F I TG+I T +DRE F +Y A + G E PL L +K+ D NDNAP F
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 244 HRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVI 303
V ++ EN + T V K+ ATD DE + L++++ YKI+ Q P F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 304 TTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV 363
T + FLDRE+ Y L++ D G GL + I + D NDN P+ +TSY +
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 364 EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
EEN + E++R++ D D T + A Y IL GN+ F I TDP TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
YE + L +GV N+A F + +SQ M T V ++++D EGP HP ++G
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQF-QMHPTPVRIQVVDVREGPAFHPSTMAFSVREG 397
Query: 484 FPAGQELLG-----YKALDPEISS-GEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRES 537
G LL Y A+D + + +RY D +W +I+ TG+++ + D++S
Sbjct: 398 I-KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS 456
Query: 538 KFVKNNQYNISVVAV-DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKP 595
K++ N Y ++A+ D G++ TGT+ + + D ND+ P I E TIC ++ +VL
Sbjct: 457 KYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP--SVLIS 514
Query: 596 VDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRH 652
V+ G PF F + + + W++ + +AIL +Q L +Y +PI +KD +
Sbjct: 515 VNEH--SYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572
Query: 653 GLVA--THMLTVRVCDCSTPSECRMKDKS---TRDVR--------------PNVILGRWA 693
M+ + CDC C + T D+ NV LG
Sbjct: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632
Query: 694 ILAMVLGSVLLL---CILFTCFC---------------------VTAKRTVKKCFPEDIA 729
I MVLG +LL+ +L C C V ++ PED
Sbjct: 633 IGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRL 692
Query: 730 QQNLIVSNTEGPGE-----------EVTEANIRLPMQTSNI-CDTSMSVGTVGG--QGIK 775
+ G + + T A + S I +T + GTV G G++
Sbjct: 693 FSAYALPGGGGTADGGGSVLGRCALQATPALLNQHPPFSEIYTNTYAAGGTVEGGVSGVE 752
Query: 776 TQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDW-QSFTQPRLGEKVYLC 834
G L + G + G YA D +F EK Y
Sbjct: 753 LNTGMGTAVG---LMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAY 809
Query: 835 GQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCI 892
++E + D + Y++EG GS GS+GCCS ++ ++ L+PKFRTLA+ C+
Sbjct: 810 ADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICL 867
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 323 bits (829), Expect = 3e-88
Identities = 257/833 (30%), Positives = 393/833 (47%), Gaps = 64/833 (7%)
Query: 107 IKVVLSARENKS-PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQN 165
++V+ + ENK PK H L R KR W P +L E + +I SD A+
Sbjct: 26 LQVLSTRNENKLLPKHPH-----LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEE 80
Query: 166 --YTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPE 223
I Y +G G+ + PF +F KDTG++ T +DRE+ F L GYA A G E
Sbjct: 81 RGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVE 140
Query: 224 YPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKI 283
PL L IK+ D NDN P F V + +V E + T V K+ ATD DEP+TL++++ Y+I
Sbjct: 141 KPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRI 200
Query: 284 LQQIPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGL-FNTGTITI 342
+ P +P F ++ DTG I TT+ LDRE+ +Y L +E RD G+ + I
Sbjct: 201 VSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQI 260
Query: 343 SLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGN 402
+ D NDN P VEEN+++VE+ R+KV D D + + A + GNE G
Sbjct: 261 RILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGY 320
Query: 403 FIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQ-TPTMCTTTVTVK 461
F I TD TNEG++ ++K ++YE + + V V N+A F K+ S+ PT + VK
Sbjct: 321 FHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPT--PIPIKVK 378
Query: 462 IIDSDEGPECHPPV---KVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWF 518
+ + EG V V +S D GQ + ++A D + RY KL D DNW
Sbjct: 379 VKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWI 438
Query: 519 EINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV--DAVGRSCTGTLVVHLDDYNDHAPQ 576
++ T +++ K+ D ES++V+N Y + +VA+ D ++ TGT++++++D ND+ P
Sbjct: 439 SVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPT 498
Query: 577 IDKEV-TICQNNEDFAVLKPVDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILR 632
+ + V TIC + E + + D DG N PF F + + ++ W I ++ T++L
Sbjct: 499 LIEPVQTICHDAE-YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQE-STSVLL 556
Query: 633 QRQNLDYNYYSVPIQIKDRHGLVA--THMLTVRVCDCSTPSECRMKDKSTRDVRPNVILG 690
Q+ + I D G +LT+ VC+C S CR + V LG
Sbjct: 557 QQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDS-----YVGLG 611
Query: 691 RWAILAMVLGSVLLLCI---LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTE 747
AI M+L +LLL + L C C + K P + L N EG E
Sbjct: 612 PAAIALMILAFLLLLLVPLLLLMCHC---GKGAKGFTPIPGTIEMLHPWNNEGAPPEDKV 668
Query: 748 ANIRLPMQTSNICDTSMSVGTVGGQG-IKTQQSFEMVKGGYTLDSNKG--GGHQTLESVK 804
LP+ VG + + +K S +VKG + + G H++L S +
Sbjct: 669 VPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR 728
Query: 805 GVG-QGDTGRYAYTDW------------------------QSFTQPRLGEKVYLCGQDEE 839
G TG T+ + F + +K +++E
Sbjct: 729 ATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDE 788
Query: 840 HKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCI 892
+ +D + Y+ E SL S+GCCS + E FLD L KF+TLA+ C+
Sbjct: 789 NHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCL 841
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 312 bits (800), Expect = 8e-85
Identities = 243/832 (29%), Positives = 385/832 (46%), Gaps = 78/832 (9%)
Query: 124 TKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFN 183
T A +R KR W E + +I SD I Y ISG G+D+ PF
Sbjct: 39 TMQQAKRRQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFG 98
Query: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFE 243
+F ++K+TGDI T +DRE+ F + A A G E PL L +KI D NDN P F
Sbjct: 99 IFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFS 158
Query: 244 HRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVI 303
++ + + EN S + V + ATD DEP+ L++++ +KI+ Q P F + +TG +
Sbjct: 159 QQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEV 218
Query: 304 TTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV 363
T T LDRE+ +Y+L++ D G+ GL I ++D NDN P F ++ Y +
Sbjct: 219 RTLTNSLDREQASSYRLVVSGADKDGE--GLSTQCECNIKVKDVNDNFPMFRDSQYSARI 276
Query: 364 EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
EEN + E+LR +V D D T + AVY GNE F I TDP TNEG+L VVK L+
Sbjct: 277 EENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALD 336
Query: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
YE + V L + V N+A+F ++ S+ +T VT+++I+ EG P K Q G
Sbjct: 337 YEQLQSVKLSIAVKNKAEFHQSVISRYRVQ-STPVTIQVINVREGIAFRPASKTFTVQKG 395
Query: 484 FPAGQ---ELLG-YKALDPEIS-SGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESK 538
+ + +LG Y+A+D + + + ++Y ++ + I+ T +++ +K ++R+S
Sbjct: 396 ISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDST 455
Query: 539 FVKNNQYNISVVAVDA-VGRSCTGTLVVHLDDYNDHAPQIDKEVTICQNNEDFAVLKPVD 597
F+ N V+A+D G++ TGT+ V + D+ND+ P E ++ V+
Sbjct: 456 FIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSART 515
Query: 598 PDGPENGPPFQFFLDNSASK---NWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKD--RH 652
+ G P+ F L++ K W+I + +A+LR ++ + Y + + + D +
Sbjct: 516 LNNRYTG-PYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNN 574
Query: 653 GLVATHMLTVRVCDCSTPSECRMK----DKSTRDVRPNV-ILGRWAILAMVLGSVLLL-- 705
LT+ VC C C TR RP+ LG AI ++LG +LLL
Sbjct: 575 RCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLA 634
Query: 706 -CILFTCFC-------VTA--------------KRTVKKCFPEDIAQQNLIVSNTEGPGE 743
+L TC C VT + ++ PED N+ V G
Sbjct: 635 PLLLLTCDCGAGSTGGVTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGA 694
Query: 744 EVTEANIRLPMQTSNICDTSMSVGT----VGGQGIKTQQSFEMVKG-------GYTLDSN 792
+ M++S +C + + GT G + T+ G G +
Sbjct: 695 DF--------MESSEVCTNTYARGTAVEGTSGMEMTTKLGAATESGGAAGFATGTVSGAA 746
Query: 793 KGGGHQTLESVKGVGQGDTGRYAYTDW------------QSFTQPRLGEKVYLCGQDEEH 840
G G T + GQ T R ++ +F +K + C ++++
Sbjct: 747 SGFGAATGVGICSSGQSGTMRTRHSTGGTNKDYADGAISMNFLDSYFSQKAFACAEEDDG 806
Query: 841 KHCEDYVCSYNYEG---KGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAK 889
+ D + Y+ EG GS GSVGCCS ++ FLD L PKF+ LA+
Sbjct: 807 QEANDCLLIYDNEGADATGSPVGSVGCCSFIADDLDDSFLDSLGPKFKKLAE 858
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 307 bits (786), Expect = 3e-83
Identities = 212/657 (32%), Positives = 337/657 (51%), Gaps = 27/657 (4%)
Query: 31 QKVY-LRVPSHLQAETLVGKVNLEECLKSASL-IRSSDPAFRILEDGSIYTTHDLILSSE 88
QKV+ + P+ + + + +C + L S P F++ DG + ++ ++
Sbjct: 33 QKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNI--TAV 90
Query: 89 RKSFSIFLSDGQRREQQEIKVVLSARENKSPKK---RHTKDTALKRSKRRWAPIPASLME 145
K+ + + E+ V++ ++ + + + + + + R KR P + E
Sbjct: 91 GKTLFVHARTPHAEDMAEL-VIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPE 149
Query: 146 NSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKY 205
N PFP+ V ++ D+ + + ++G GVD+EP +F I ++TG + TR++DRE
Sbjct: 150 NQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVI 208
Query: 206 EQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVT 265
+ L+ T +G E P+PL + + D NDN P F I V E +GT+V ++T
Sbjct: 209 AVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMT 268
Query: 266 ATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTG-VITTTTP-FLDREKCDT--YQ 319
A D D+P T + L+Y I QQ PD P F I P+ G ++T +P LDRE + Y+
Sbjct: 269 AFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYE 328
Query: 320 LIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQD 379
LI+E +DM G GL T T TI ++D+ND+ P FT+ + VEE + V I+ + V+D
Sbjct: 329 LIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVED 387
Query: 380 QDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINE 439
+D P T +A Y I+ GN +F I T+P TNEG+L VVKPL+YE++ L + V NE
Sbjct: 388 KDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENE 447
Query: 440 AQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE 499
S + T TV + ++D +EGP +P ++ Q+ G LL A DP+
Sbjct: 448 DPLVPDVSYGPSS--TATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPD 505
Query: 500 ISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSC 559
+ +RY D W IN G + T VLDRES FV N+ Y +A+D+
Sbjct: 506 SLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPA 565
Query: 560 TGT--LVVHLDDYNDHAPQIDKEVT-ICQNNEDFAV--LKPVDPDGPENGPPFQFFLDNS 614
TGT L++ L+D ND+AP I V +C + ++ +V L D D N PF+F +
Sbjct: 566 TGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQ 625
Query: 615 A--SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHM--LTVRVCDC 667
A K W I + + A++ QNL+ Y++PI + D T++ L V+VC C
Sbjct: 626 AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 297 bits (760), Expect = 3e-80
Identities = 216/638 (33%), Positives = 312/638 (48%), Gaps = 27/638 (4%)
Query: 128 ALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYI 187
AL R +R W P S+ EN P + QI+SD Q ++ YSI GPGVD+EP +F I
Sbjct: 39 ALSRVRRAWVIPPISVSENHKR-LPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSI 97
Query: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVT 247
+K TG +F +DREK ++F L +A G E P L I + D NDN P F
Sbjct: 98 DKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAF 157
Query: 248 IFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
V E GT V + ATD D+P+T + L++ ILQQ P+ FSI TG I T
Sbjct: 158 TGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQ--GSPELFSIDELTGEIRTVQ 215
Query: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENR 367
LDRE Y L ++V DM G GL T + I+L+D NDN P FT + E E
Sbjct: 216 VGLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEAV 273
Query: 368 IDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVN 427
V++ R++V+D+DLP +P+ A + IL+G+ +G F I TDP TNEGVL +VK L+YE
Sbjct: 274 SGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESC 333
Query: 428 RQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAG 487
L+V V NEA AA V V + D++E P +G P G
Sbjct: 334 EHYELKVSVQNEAPLQAAALRAERGQ--AKVRVHVQDTNEPPVFQENPLRTSLAEGAPPG 391
Query: 488 QELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNI 547
+ + A DP+ + L Y K D ++W +++ TG ++T VL S F+K Y
Sbjct: 392 TLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRA 451
Query: 548 SVVAVDAVG--RSCTGTLVVHLDDYNDHAPQI--DKEVTICQ--NNEDFAVLKPVDPDGP 601
V+A D R+ TGTL + + + NDHAP + ++C + +L D D P
Sbjct: 452 IVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDLP 511
Query: 602 ENGPPFQFFLD---NSASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKD--RHGLVA 656
+G PF F L +NW++ + + A LR R + + + + ++D +
Sbjct: 512 PHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPPQQR 571
Query: 657 THMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTA 716
L V VC C C + + LG L +VL S LLL +L + A
Sbjct: 572 EQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLG---ALVIVLASALLLLVLVLLVALRA 628
Query: 717 ---KRTVKKCF---PEDIAQQNLIVSNTEGPGEEVTEA 748
K++ K P+D + N++ + +G GEE +A
Sbjct: 629 RFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDA 666
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 293 bits (750), Expect = 5e-79
Identities = 204/662 (30%), Positives = 340/662 (51%), Gaps = 40/662 (6%)
Query: 106 EIKVVLSARENKSPKKRHTKDTA---LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA 162
++ ++ S ++ + TK+ L+RSKRRW L E GPFP+ + ++ ++
Sbjct: 23 QVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM 82
Query: 163 AQNYTIFYSISGPGVDKEP-FNLFYIEK-DTGDIFCTRSIDREKYEQFALY-GYATTADG 219
+ N ++ Y ISGPGVD+ P LF +E + G I+ R +DRE F +Y + G
Sbjct: 83 SYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTG 142
Query: 220 YAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRL 279
+ L I+I D ND+AP F + TV EN +G + ++ A DLDE +T ++++
Sbjct: 143 KIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQV 202
Query: 280 KYKILQQIPDHPKH-FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Y ++ Q P + F + +G I + LD E + L++ RD G +P L +T
Sbjct: 203 LYFLISQTPLLKESGFRVDRLSGEIRLSG-CLDYETAPQFTLLIRARDCG-EP-SLSSTT 259
Query: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
T+ + +++ N++ P+FT+ +Y ++ E R +LR+ VQD+D P T +A + IL GN
Sbjct: 260 TVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGN 319
Query: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQ--FSKAASSQTP--TMC 454
E G+F ISTDP TNEG+L V+KPL+YE L + V NE + F + Q P
Sbjct: 320 EEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAA 379
Query: 455 TTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDE 514
+ TV+V++ D+++ P HP ++ ++G G L + A+DP+ +RY+ + D
Sbjct: 380 SATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDP 435
Query: 515 DNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYND 572
NW +++++G + T++ +DRES V N+ Y I + AVD ++ TGTL++ L D ND
Sbjct: 436 ANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDIND 495
Query: 573 HAPQI---DKEVTICQNNEDFAVLKPV-----DPDGPENGPPFQFFLDN---SASKNWNI 621
+ P + + + +C++ AV +P+ DPD PF F LDN +A W +
Sbjct: 496 NVPTLRPRSRYMEVCES----AVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKL 551
Query: 622 EEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTR 681
G++ L ++L Y VP+ I D+ GL + VR+C C++ C
Sbjct: 552 GRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTC----VELA 607
Query: 682 DVRPNVILGR-WAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEG 740
D + +G + + A + + L L C+ V + D Q L++ N E
Sbjct: 608 DAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAES 667
Query: 741 PG 742
G
Sbjct: 668 KG 669
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 275 bits (703), Expect = 1e-73
Identities = 220/657 (33%), Positives = 339/657 (51%), Gaps = 52/657 (7%)
Query: 131 RSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYIEK 189
R+KR W ++E +G P +V ++ SD + + +I Y +SG G ++F I++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 190 DTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVTI 248
+TGDI T+ +DRE+ + L A P P +IKI+D NDN P F
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 249 FTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
VPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN- 366
P +DRE D Y L+++ +DM GQ GL T ++T++L D NDNPP F SY V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 367 RIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEV 426
+ + R+K D D+ +++ YKI+ G+ G F IS D T EG++ + K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 427 NRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPA 486
L++ N+ S P TTTV + + D DE P P+ ++ +
Sbjct: 334 KTSYTLRIEAANK-DADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQV 392
Query: 487 GQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQ 544
G + A DP+ SS +RY + D + +F I+ ++G + T K LDRE+ N
Sbjct: 393 GNIIGTVAAHDPD-SSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAI 447
Query: 545 YNISVVAVDA-----VGRSCTGTLVVHLDDYNDHAPQ--IDKEVTICQNNEDFAVLK--- 594
+NI+V+A+++ VGR G + + + D ND+AP+ +D E T+C+N + V++
Sbjct: 448 HNITVLAMESQNPSQVGR---GYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKIS 504
Query: 595 PVDPDGPENGPPFQFFLDNSASKNWNIEEKDGK--TAILRQRQN----LDYNYYSVPIQI 648
VD D P NG F F L A+ N N KD K TA + R+N + + Y +PI I
Sbjct: 505 AVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 649 KD--RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRW-AILAMVLGSVLLL 705
D L +T+ LT+RVCDC + + + + G AILA VL ++L+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLI 624
Query: 706 CILFTCFCVTAKRTVKK--CFPED-IAQQNLIVSNTEGPGEEVTEANIRLPMQTSNI 759
++ VT +R K+ F E+ ++N++ + EG GEE TEA ++ N+
Sbjct: 625 LLI-----VTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNV 676
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 275 bits (703), Expect = 1e-73
Identities = 220/657 (33%), Positives = 339/657 (51%), Gaps = 52/657 (7%)
Query: 131 RSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYIEK 189
R+KR W ++E +G P +V ++ SD + + +I Y +SG G ++F I++
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 190 DTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVTI 248
+TGDI T+ +DRE+ + L A P P +IKI+D NDN P F
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 249 FTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
VPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN- 366
P +DRE D Y L+++ +DM GQ GL T ++T++L D NDNPP F SY V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 367 RIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEV 426
+ + R+K D D+ +++ YKI+ G+ G F IS D T EG++ + K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 427 NRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPA 486
L++ N+ S P TTTV + + D DE P P+ ++ +
Sbjct: 334 KTSYTLRIEAANK-DADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQV 392
Query: 487 GQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQ 544
G + A DP+ SS +RY + D + +F I+ ++G + T K LDRE+ N
Sbjct: 393 GNIIGTVAAHDPD-SSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAI 447
Query: 545 YNISVVAVDA-----VGRSCTGTLVVHLDDYNDHAPQ--IDKEVTICQNNEDFAVLK--- 594
+NI+V+A+++ VGR G + + + D ND+AP+ +D E T+C+N + V++
Sbjct: 448 HNITVLAMESQNPSQVGR---GYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKIS 504
Query: 595 PVDPDGPENGPPFQFFLDNSASKNWNIEEKDGK--TAILRQRQN----LDYNYYSVPIQI 648
VD D P NG F F L A+ N N KD K TA + R+N + + Y +PI I
Sbjct: 505 AVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 649 KD--RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRW-AILAMVLGSVLLL 705
D L +T+ LT+RVCDC + + + + G AILA VL ++L+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLI 624
Query: 706 CILFTCFCVTAKRTVKK--CFPED-IAQQNLIVSNTEGPGEEVTEANIRLPMQTSNI 759
++ VT +R K+ F E+ ++N++ + EG GEE TEA ++ N+
Sbjct: 625 LLI-----VTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNV 676
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 274 bits (700), Expect = 3e-73
Identities = 231/782 (29%), Positives = 373/782 (47%), Gaps = 75/782 (9%)
Query: 131 RSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYIEK 189
R KR W ++E +GP PQ+V ++ S++ + + ++ Y ++G G +F I+
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAG----TIFIIDD 105
Query: 190 DTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVTI 248
TGDI T+S+DRE+ + L+ A P P IIK++D NDNAP F I
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 249 FTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ P TGVI T
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----YFSVDPKTGVIRTAL 221
Query: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN- 366
+DRE + Y ++++ +DM GQ GL + T+ I+L D NDNPP F + Y V E+
Sbjct: 222 HNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESA 281
Query: 367 RIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEV 426
++ + ++K D D + ++ Y I+ G+ G F ISTD T EG+L + KPLNYE
Sbjct: 282 QVGSAVGKIKANDADTGS--NADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEK 339
Query: 427 NRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPA 486
+ L + N S P T + + + D DE P P +++ +
Sbjct: 340 KKSYTLNIEGAN-THLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKI 398
Query: 487 GQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQ 544
G + A DP+ S+ +RY ++D +F I+ +TG +RT KVLDRE +
Sbjct: 399 GTVVGTVLAQDPD-STNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDRE----ETPW 453
Query: 545 YNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDKE--VTICQNNEDFAVLKPV---D 597
YNI+V A +D T+ + + D ND+ P++ +E + +C+N++ V+ + D
Sbjct: 454 YNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATD 513
Query: 598 PDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNLD---YNYYSVPIQIKDR 651
D NGP F FFLD N N + +D +IL +R+ + Y +PI I D
Sbjct: 514 KDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDG 573
Query: 652 --HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILF 709
L ++ LT+RVC C + R++ + L A++A++L ++LL I+
Sbjct: 574 GIPSLSSSSTLTIRVCACE--RDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVV 631
Query: 710 TCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTV 769
+ + E+ ++N++ + EG GEE TEA D +
Sbjct: 632 LFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEA-----------FDITALRNPS 680
Query: 770 GGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGE 829
+ +K ++ + HQT +++ + D Q F + RL E
Sbjct: 681 AAEELKYRRDIRP-------EVKLTPRHQTSSTLESI-----------DVQEFIKQRLAE 722
Query: 830 KVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGC--CSDRQEEEGLEFLDHLEPKFRTL 887
+ D + +Y YEG+ S AGS+ + Q ++ +L P+F+ L
Sbjct: 723 -----ADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKL 777
Query: 888 AK 889
A+
Sbjct: 778 AE 779
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 265 bits (678), Expect = 1e-70
Identities = 232/794 (29%), Positives = 363/794 (45%), Gaps = 92/794 (11%)
Query: 129 LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA-AQNYTIFYSISGPGVDKEPFNLFYI 187
L+RSKR W ++E GP P V ++ SD + + I Y +SG G +F I
Sbjct: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFVI 103
Query: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHRV 246
+ +G+I T+++DRE+ Q+ L A D P E P I+K++D NDN P F H
Sbjct: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
Query: 247 TIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITT 305
VPE GTSV +VTA+D D+P ++ +L Y IL+ P +FS+ TG+I T
Sbjct: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGIIRT 219
Query: 306 TTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEE 365
P +DRE + Y ++++ +DMGG GL T +TI+L D NDNPP F ++ Y V E
Sbjct: 220 ALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279
Query: 366 NRI-DVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNY 424
+ E+ R+K +D D+ + Y I+ G+ +F I+TD T EGV+ + KP+++
Sbjct: 280 AAVPGEEVGRVKAKDPDIGE--NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDF 337
Query: 425 EVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGF 484
E R L+V N S P T TV + + D+DE P P + + Q+
Sbjct: 338 ETKRAYSLKVEAAN-VHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 396
Query: 485 PAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKN 542
AG + A DP+ ++ +RY + D D +F IN G ++T K LDRE +
Sbjct: 397 AAGTVVGRVHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ET 451
Query: 543 NQYNISVVAVDAVGR--SCTGTLVVHLDDYNDHAPQI--DKEVTICQ-------NNEDFA 591
NI+V A + R + + + D ND+AP+ E IC+ +N+
Sbjct: 452 AWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIV 511
Query: 592 VLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKT----------AILRQRQNLDYNY 641
+ D D NGP F F L N N +D + RQ+Q+L
Sbjct: 512 TISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDL---- 567
Query: 642 YSVPIQIKDR--HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVL 699
Y +PI I D + +T+ LT++VC C + + + G L +L
Sbjct: 568 YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG---ALIAIL 624
Query: 700 GSVLLLCILFTCFCVTAKRTVKK---CFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQT 756
+++L ++ F VT +R K+ F E+ ++N+I + EG GEE TEA +Q
Sbjct: 625 ACIVILLVIVVLF-VTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQN 683
Query: 757 SNICDTSMSVGTVGGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAY 816
+ + G + + IK + + M + G N
Sbjct: 684 PDGIN-----GFIPRKDIKPEYQY-MPRPGLRPAPNS----------------------- 714
Query: 817 TDWQSFTQPRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGL-- 874
D F R+ E ++ D + Y YEG+GS+AGS+ + L
Sbjct: 715 VDVDDFINTRIQE-----ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDY 769
Query: 875 EFLDHLEPKFRTLA 888
++L + P+F+ LA
Sbjct: 770 DYLQNWGPRFKKLA 783
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 252 bits (643), Expect = 1e-66
Identities = 212/659 (32%), Positives = 322/659 (48%), Gaps = 45/659 (6%)
Query: 110 VLSARENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTI 168
+LS+R +S K L R KR W L+E G Q+V ++ SD + + ++
Sbjct: 36 ILSSRVPRSDGK------ILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSL 89
Query: 169 FYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LP 227
Y +SG G LF I++ TGDI TR IDRE+ + L A P P
Sbjct: 90 KYILSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESE 145
Query: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQ 286
+IKI D NDN P F + +VPE GTSV +VTATD D+P ++ R+ Y ILQ
Sbjct: 146 FVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQG 205
Query: 287 IPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLED 346
P +FS+ P+TG+I T P ++RE + YQ++++ +DMGGQ GL T T+ I+L D
Sbjct: 206 QP----YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTD 261
Query: 347 ENDNPPSFTE-TSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFII 405
NDNPP F + T ++ +E + + I +K D D +++ Y+I+ G+ F I
Sbjct: 262 VNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDI 319
Query: 406 STDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDS 465
T+ +T EG++ V KPL+YE R L+V N P TT V + I D
Sbjct: 320 VTEKDTQEGIITVKKPLDYESRRLYTLKVEAEN-THVDPRFYYLGPFKDTTIVKISIEDV 378
Query: 466 DEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE-ISSGEGLRYQKLGDEDNWFEINQHT 524
DE P + + + G + A DP+ ISS + D D F I+
Sbjct: 379 DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGN 438
Query: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSCTG--TLVVHLDDYNDHAPQ--IDKE 580
G L T K LDRE + +N++V+A + T + V + D ND+APQ + +
Sbjct: 439 GSLYTSKPLDRE----LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYD 494
Query: 581 VTICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQN- 636
+C+N + + VD D P G F FF + + N+ +++ + TA + R+N
Sbjct: 495 TFVCENARPGQLIQTISAVDKDDPLGGQKF-FFSLAAVNPNFTVQDNEDNTARILTRKNG 553
Query: 637 ---LDYNYYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGR 691
+ + Y +P+ I D + +T LT+RVC C S+ M+ S + L
Sbjct: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACD--SQGNMQSCSAEALLLPAGLST 611
Query: 692 WAILAMVLGSVLLLCI--LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
A++A++L ++LL I LF K+ EDI + N++ N EG GEE T+A
Sbjct: 612 GALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDI-RDNIVSYNDEGGGEEDTQA 669
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 249 bits (637), Expect = 6e-66
Identities = 226/787 (28%), Positives = 359/787 (45%), Gaps = 80/787 (10%)
Query: 129 LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYI 187
L RSKR W ++E GP P V ++ +D + I Y +SG G +F I
Sbjct: 56 LNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAG----TIFQI 111
Query: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHRV 246
TGDI + +DRE+ ++ L A + P E P IIK++D NDNAP F +
Sbjct: 112 NDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGP 171
Query: 247 TIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITT 305
TVPE GTSV VTATD D+P ++ +L Y IL+ P +FSI P+T +I T
Sbjct: 172 YHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP----YFSIEPETAIIKT 227
Query: 306 TTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEE 365
P +DRE + Y ++++ +DMGG GL T T+T++L D NDNPP F ++ Y V E
Sbjct: 228 ALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPE 287
Query: 366 NRI-DVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNY 424
+ + I R+K DQD+ S Y I+ G+ F I++D +G++ + KPL++
Sbjct: 288 DVVLGTAIGRVKANDQDIGENAQSS--YDIIDGDGTALFEITSDAQAQDGIIRLRKPLDF 345
Query: 425 EVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGF 484
E + L+V N S + P T TV + + D+DE P P +++ +
Sbjct: 346 ETKKSYTLKVEAAN-VHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENA 404
Query: 485 PAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKN 542
+ A DP+I+S +R+ + D + F IN G + LDRE
Sbjct: 405 ALNSVIGQVTARDPDITSSP-IRFSIDRHTDLERQFNINADDGKITLATPLDRELSV--- 460
Query: 543 NQYNISVVAVDAVGRSCTGTLVVHLD--DYNDHAPQI--DKEVTICQNNEDFAVLKPV-- 596
+NI+++A + S + V + D ND+AP+ + E +C+N + V++ V
Sbjct: 461 -WHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSA 519
Query: 597 -DPDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNLD---YNYYSVPIQIK 649
D D P+NG F + L N N + +D +IL + + Y +PI I
Sbjct: 520 MDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIIS 579
Query: 650 DRHG--LVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCI 707
D L +T LT+RVC CS + + + + +G L +L ++LL +
Sbjct: 580 DSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMG---ALIAILACIILLLV 636
Query: 708 LFTCFCVTAKRTVKKCF---PEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSM 764
+ F VT +R + ++ ++N+I + EG GEE TEA +Q + +
Sbjct: 637 IVVLF-VTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGIN--- 692
Query: 765 SVGTVGGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQ 824
G + + IK F +G + V G D F
Sbjct: 693 --GFLPRKDIKPDLQFMPRQG-----------------LAPVPNG-------VDVDEFIN 726
Query: 825 PRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGC--CSDRQEEEGLEFLDHLEP 882
RL E ++ D + Y YEG+GS+AGS+ + ++ ++L P
Sbjct: 727 VRLHE-----ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGP 781
Query: 883 KFRTLAK 889
+F+ L +
Sbjct: 782 RFKRLGE 788
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 246 bits (627), Expect = 9e-65
Identities = 206/650 (31%), Positives = 323/650 (49%), Gaps = 48/650 (7%)
Query: 125 KDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFN 183
K + +R+KR W ++E G P +V ++ SD + + +I Y +SG G
Sbjct: 50 KPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI---- 105
Query: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYF 242
+F I+ TGDI + +DRE+ Q+ L A P P IIKI+D NDN P F
Sbjct: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
Query: 243 EHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTG 301
+ TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ TG
Sbjct: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTG 221
Query: 302 VITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVT 361
VI T +DRE + Y++I++ +DMGGQ GL T T+ I+L D NDNPP F + Y
Sbjct: 222 VIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQM 281
Query: 362 EVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKP 421
V E+ + +V +DL +++ Y I+ G+ F ISTDPN G++ V KP
Sbjct: 282 SVLES-APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKP 340
Query: 422 LNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVI 478
L++E + L+V N E +F P TTTV + + D DE P P +
Sbjct: 341 LSFESKKSYTLKVEGANPHLEMRFLNLG----PFQDTTTVHISVEDVDEPPVFEPGFYFV 396
Query: 479 QSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRE 536
+ + G + A DP++++ +RY + D +F ++ TG L T + LDRE
Sbjct: 397 EVPEDVAIGTTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE 455
Query: 537 SKFVKNNQYNISVVAVDAVGRSCTGTLVVHLD--DYNDHAPQIDK--EVTICQN---NED 589
+ + +NI+V+A++ S G++ V + D ND+AP+ + E +C+N +
Sbjct: 456 ----EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQL 511
Query: 590 FAVLKPVDPDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNL---DYNYYS 643
+ VD D P NG F + L A+ N N + +D IL +R + + +
Sbjct: 512 IQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFH 571
Query: 644 VPIQIKD--RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGS 701
+PI I D + L +T LT++VC C + + S V L R A++A +L
Sbjct: 572 LPILIADSGQPVLSSTGTLTIQVCSCD--DDGHVMSCSPEAYMLPVSLSRGALIA-ILAC 628
Query: 702 VLLLCILFTCFCVTAKRTVKKCF---PEDIAQQNLIVSNTEGPGEEVTEA 748
+ +L +L ++ +R K+ + E+ +N++ + EG GEE TEA
Sbjct: 629 IFVLLVL-VLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEA 677
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 245 bits (626), Expect = 1e-64
Identities = 202/642 (31%), Positives = 317/642 (49%), Gaps = 42/642 (6%)
Query: 130 KRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNY-TIFYSISGPGVDKEPFNLFYIE 188
+R KR W ++E +G PQ+V ++ SD + T+ Y++SG G +F I+
Sbjct: 50 QRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAG----TVFTID 105
Query: 189 KDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVT 247
+ TGDI RS+DRE+ + L A + P P IIK++D NDN P F
Sbjct: 106 ETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPY 165
Query: 248 IFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTT 306
+ TVPE G V +V ATD D+P ++ R+ Y ILQ P +FSI P TGVI T
Sbjct: 166 VATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP----YFSIDPKTGVIRTA 221
Query: 307 TPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV-EE 365
P +DRE + YQ++++ +DMGGQ GL T + I+L D NDNPP F ++ + +V E
Sbjct: 222 LPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPES 281
Query: 366 NRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYE 425
+ I I R++ D D +++ Y I+ G+ F I TD +T EGV+ + KPL++E
Sbjct: 282 SPIGSAIGRIRAVDPDFGQ--NAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFE 339
Query: 426 VNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFP 485
+ +V N S P T TV + ++D DE P P+ ++ + P
Sbjct: 340 TKKAYTFKVEASN-LHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTP 398
Query: 486 AGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNN 543
G + A D ++ S +RY D D++F I+ + G + T ++LDRES
Sbjct: 399 VGTIIGAVTAQDLDVGS-SAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES----TA 453
Query: 544 QYNISVVAVDAVGRSCTG--TLVVHLDDYNDHAPQID--KEVTICQN---NEDFAVLKPV 596
QYN S++A T +++++ D N+ P+I E +C+N + ++
Sbjct: 454 QYNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQIVSAA 513
Query: 597 DPDGPENGPPFQFFLDNSAS--KNWNIEEKDGKTAILRQRQN----LDYNYYSVPIQIKD 650
D D G F F L A+ N+ + + TA + R+N Y +P+ I+D
Sbjct: 514 DRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIED 573
Query: 651 RHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCI- 707
V +T+ +T+RVC C S+ + + + V L A++A++L V+LL I
Sbjct: 574 SSYPVQSSTNTMTIRVCRCD--SDGTILSCNVEAIFLPVGLSTGALIAILLCIVILLAIV 631
Query: 708 -LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
L+ K+ EDI + N+I + EG GEE T+A
Sbjct: 632 VLYVALRRQKKKDTLMTSKEDI-RDNVIHYDDEGGGEEDTQA 672
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 235 bits (599), Expect = 2e-61
Identities = 234/812 (28%), Positives = 372/812 (45%), Gaps = 91/812 (11%)
Query: 111 LSARENKSPKKRHTKDTA------LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ 164
LS R + P K+ + + L RSKR W L+E G Q+V ++ SD +
Sbjct: 24 LSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDR 83
Query: 165 -NYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPE 223
+ ++ Y +SG G +LF I ++TGDI T+ +DRE+ + L A P
Sbjct: 84 GDGSLKYILSGDGAG----DLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPV 139
Query: 224 YP-LPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKY 281
P IIKI D NDN P F V TVPE GT V +VTATD D+P ++ ++ Y
Sbjct: 140 EPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVY 199
Query: 282 KILQQIPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTIT 341
ILQ P +FS+ +TG+I T +DRE + YQ++++ +DMGGQ GL T T+
Sbjct: 200 SILQGQP----YFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVN 255
Query: 342 ISLEDENDNPPSFTETSYVTEV-EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNEN 400
I+L D NDNPP F +++Y + E + I R+K D D+ +++ Y I G
Sbjct: 256 ITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGE--NAEIEYSITDGEGL 313
Query: 401 GNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTT 457
F + TD T EG++ V K L++E + L+V N E +F P + T
Sbjct: 314 DMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLG----PFKDSAT 369
Query: 458 VTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDED 515
V + + D DE P ++Q ++ + A DP+ ++ ++Y + D D
Sbjct: 370 VRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPD-AARNPVKYSVDRHTDMD 428
Query: 516 NWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVA--VDAVGRSCTGTLVVHLDDYNDH 573
F I+ G + T K+LDRE+ +NI+V+A ++ +S L + + D ND+
Sbjct: 429 RIFNIDSGNGSIFTSKLLDRETLL----WHNITVIATEINNPKQSSRVPLYIKVLDVNDN 484
Query: 574 APQIDK--EVTICQN---NEDFAVLKPVDPDGPENGPPFQFFL--DNSASKNWNIEEKDG 626
AP+ + E +C+ ++ L VD D P +G F F L + ++ N+ I++
Sbjct: 485 APEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKD 544
Query: 627 KTAILRQRQN----LDYNYYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKST 680
TA + R+N + + Y +P+ I D V +T +TVRVC C M+
Sbjct: 545 NTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACD--HHGNMQSCHA 602
Query: 681 RDVRPNVILGRWAILAMVLGSVLLL--CILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNT 738
+ L A++A++L V+LL +LF K+ EDI + N++ N
Sbjct: 603 EALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDI-RDNIVSYND 661
Query: 739 EGPGEEVTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSFEMVKGGYTLDSNKGGGHQ 798
EG GEE T+A +GT ++ ++ NK
Sbjct: 662 EGGGEEDTQA---------------FDIGT--------------LRNPEAIEDNKLRRDI 692
Query: 799 TLESVKGVGQGDTGRYAYTDWQSFTQPRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSL 858
E++ + T R TD + F RL E + D + +Y YEG GS+
Sbjct: 693 VPEALFLPRRTPTAR-DNTDVRDFINQRLKE-----NDTDPTAPPYDSLATYAYEGTGSV 746
Query: 859 AGSVGCCSD--RQEEEGLEFLDHLEPKFRTLA 888
A S+ ++ ++L P+F+ LA
Sbjct: 747 ADSLSSLESVTTDADQDYDYLSDWGPRFKKLA 778
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 227 bits (578), Expect = 4e-59
Identities = 196/653 (30%), Positives = 320/653 (49%), Gaps = 50/653 (7%)
Query: 124 TKDTA--LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKE 180
TKD L+R+KR W L+E G Q+V ++ +D + + + Y ++G G
Sbjct: 41 TKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-- 98
Query: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTAD-GYAPEYPLPLIIKIEDDNDNA 239
+LF I+++TGDI + +DRE+ + L A G E IIKI D NDN
Sbjct: 99 --SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNE 156
Query: 240 PYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHP 298
P F + +VPE GTSV +VTATD D+ + ++ ++ Y ILQ P +FS+ P
Sbjct: 157 PKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDP 212
Query: 299 DTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETS 358
++G+I T P + RE + YQ++++ +DMGGQ GL T T+ I+L D N+NPP F +++
Sbjct: 213 ESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQST 272
Query: 359 Y-VTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLC 417
Y E + + R+K D D+ +++ Y I +G+ F + TD +T EG++
Sbjct: 273 YQFNSPESVPLGTHLGRIKANDPDVGE--NAEMEYSIAEGDGADMFDVITDKDTQEGIIT 330
Query: 418 VVKPLNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPP 474
V + L++E L+V N + +F P T V + + D DE P
Sbjct: 331 VKQNLDFENQMLYTLRVDASNTHPDPRFLHLG----PFKDTAVVKISVEDIDEPPVFTKV 386
Query: 475 VKVIQSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKV 532
+I+ + G + A DP+ + ++Y + D D F I+ G + TLK
Sbjct: 387 SYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKA 445
Query: 533 LDRESKFVKNNQYNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDK--EVTICQNNE 588
LDRES + +NI+V A ++ +S + + + D NDHAP+ E +C+N +
Sbjct: 446 LDRES----SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAK 501
Query: 589 DFAVLKPV---DPDGPENGPPFQFFLDNSASKNWN---IEEKDGKTAILRQRQNLDYN-- 640
+++ V D D P G F F + N N ++ KD I+ ++ N
Sbjct: 502 PGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKM 561
Query: 641 -YYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAM 697
Y +PI I D + +T LT+RVC C ++ M+ + + + L A++A+
Sbjct: 562 STYLLPILIFDNDYPIQSSTGTLTIRVCACD--NQGNMQSCTAEALILSAGLSTGALVAI 619
Query: 698 VLGSVLLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEA 748
+L VL+L IL F ++ K+ +D + N++ N EG GEE T+A
Sbjct: 620 LL-CVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQA 671
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 218 bits (556), Expect = 2e-56
Identities = 190/646 (29%), Positives = 307/646 (47%), Gaps = 49/646 (7%)
Query: 128 ALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNY-TIFYSISGPGVDKEPFNLFY 186
AL R++R W ++E GP P + ++ SD + Y ++G G +F
Sbjct: 38 ALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFV 93
Query: 187 IEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHR 245
I++ TG+I T+S+DRE+ Q+ L A P E P IIK++D NDN P F
Sbjct: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLG 153
Query: 246 VTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVIT 304
TVPE GTSV +VTA D D+P ++ +L Y +L +P FS+ P TGV+
Sbjct: 154 PYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVR 209
Query: 305 TTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVE 364
T P +DRE + + ++++ +DMGG GL + T+T++L D NDNPP F ++ Y V
Sbjct: 210 TAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVV 269
Query: 365 ENRIDVEIL-RMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
E ++ R++ QD DL + ++ Y IL G + F ISTD +G+L V KPL+
Sbjct: 270 ETAGPGTLVGRLRAQDPDLGD--NALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLD 327
Query: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
+E R +V N A + P +V V + D+ E P + +
Sbjct: 328 FESQRSYSFRVEATN-TLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPEN 386
Query: 484 FPAGQELLGYKALDPEISSGEGLRYQKL--GDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
G + A D + S +RY L D + F I G + T LDRE++
Sbjct: 387 KAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREAR--- 442
Query: 542 NNQYNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDK--EVTICQN---NEDFAVLK 594
+N++V+A +D+ ++ + + D ND+APQ+ + + +C + + V++
Sbjct: 443 -AWHNLTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIR 501
Query: 595 PVDPDGPENGPPFQFFLDNSASKNWNIEE-KDGKTAILRQRQNLDYNY--YSVPIQIKD- 650
+D D N F N+ +++ +DG ++L + + Y VPI++ D
Sbjct: 502 ALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDW 561
Query: 651 -RHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVI-----LGRWAILAMV--LGSV 702
+ L +T +TV VC C D S P L A+LA++ +G++
Sbjct: 562 GQPALSSTATVTVSVCRC-------QPDGSVASCWPEAHLSAAGLSTGALLAIITCVGAL 614
Query: 703 LLLCILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
L L +LF + + ED+ ++N+I + EG GEE TEA
Sbjct: 615 LALVVLFVALRRQKQEALMVLEEEDV-RENIITYDDEGGGEEDTEA 659
Score = 32.7 bits (73), Expect = 1.5
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 845 DYVCSYNYEGKGSLAGSVGCCSDRQEEEG----LEFLDHLEPKFRTLAK 889
D V Y YEG+GS GS+ E G E LD P FRTLA+
Sbjct: 723 DSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAE 771
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 218 bits (555), Expect = 2e-56
Identities = 191/660 (28%), Positives = 317/660 (48%), Gaps = 52/660 (7%)
Query: 118 SPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPG 176
+P R R KR W ++E G P +V +I SD+ + + I Y+ISG G
Sbjct: 46 APGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEG 105
Query: 177 VDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATT-ADGYAPEYPLPLIIKIEDD 235
+F I++ TGDI +DRE+ + L A A E IIK++D
Sbjct: 106 AG----TIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDI 161
Query: 236 NDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDT-LHTRLKYKILQQIPDHPKHF 294
ND+ P F H I +V E +GTSV +V A+D D+P RL Y +L D HF
Sbjct: 162 NDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVL----DGEHHF 217
Query: 295 SIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSF 354
++ P TGVI T P LDRE + Y+++++ DM GQ GL + T+TI + D NDNPP F
Sbjct: 218 TVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRF 277
Query: 355 TETSYVTEVEENR-IDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGN--FIISTDPNT 411
+ Y ++E+ I + R+K +D D+ ++ Y + + +G F ++TD +T
Sbjct: 278 PQKMYQFSIQESAPIGTAVGRVKAEDSDVGE--NTDMTYHLKDESSSGGDVFKVTTDSDT 335
Query: 412 NEGVLCVVKPLNYE---VNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEG 468
E ++ V K L++E V+ ++ + + +F+ + + + V V + D DE
Sbjct: 336 QEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAI----VRVAVTDVDEP 391
Query: 469 PECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGD 526
PE PP +++ Q+ G + A DP+ ++ +RY + D D F+I+ TG
Sbjct: 392 PEFRPPSGLLEVQEDAQVGSLVGVVTARDPD-AANRPVRYAIDRESDLDQIFDIDADTGA 450
Query: 527 LRTLKVLDRESKFVKNNQYNISVVAVDAVGRS--CTGTLVVHLDDYNDHAPQI--DKEVT 582
+ T K LDRE+ +NI+V+A++A + +L + + D ND+ P++ E
Sbjct: 451 IVTGKGLDRETA----GWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAA 506
Query: 583 ICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWN---IEEKDGKTAILRQ--- 633
+C++ + + VD D P+ G F F L A N + ++ +D A+ Q
Sbjct: 507 VCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVG 566
Query: 634 --RQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGR 691
RQ D + + + L +T LT+R+C C S ++ +T L
Sbjct: 567 FNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCD--SSGTIQSCNTTAFVMAASLSP 624
Query: 692 WAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPED---IAQQNLIVSNTEGPGEEVTEA 748
A++A+++ +L+ ++ +T +R K D + N+I N EG GE+ TEA
Sbjct: 625 GALIALLV--CVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEA 682
>gi|119703744 desmoglein 1 preproprotein [Homo sapiens]
Length = 1049
Score = 218 bits (554), Expect = 3e-56
Identities = 138/462 (29%), Positives = 229/462 (49%), Gaps = 4/462 (0%)
Query: 128 ALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYI 187
+++R KR W A+ E + +I SD A N + Y ISG G+D+ P+ +F I
Sbjct: 43 SIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVI 102
Query: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVT 247
+ TG+I T +DRE F +Y A + G E PL L +++ D NDN P F
Sbjct: 103 NQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATF 162
Query: 248 IFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
+ EN + T V + ATD DEP+ L++++ +KI++Q P F I+ +TG I T
Sbjct: 163 AGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMN 222
Query: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENR 367
FLDRE+ Y L + D G G+ I + D NDN P ++SY E++EN
Sbjct: 223 NFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENT 282
Query: 368 IDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVN 427
++ +L ++V D D + + AV + GNE F I + TN G+L VVKPL+YE
Sbjct: 283 LNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAM 342
Query: 428 RQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAG 487
+ + L +GV N+A+F + SQ + + ++V +++ EGP P K +
Sbjct: 343 QSLQLSIGVRNKAEFHHSIMSQY-KLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSN 401
Query: 488 QELLGYKALDPEIS-SGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYN 546
++ + A D + +RY + + ++ TG L + +E + +Y
Sbjct: 402 DKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQ 461
Query: 547 ISVVAV-DAVGRSCTGTLVVHLDDY-NDHAPQIDKEVTICQN 586
+++++ D + R+CTGT+ +++ + ND + I N
Sbjct: 462 GTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTN 503
Score = 93.2 bits (230), Expect = 1e-18
Identities = 166/731 (22%), Positives = 279/731 (38%), Gaps = 114/731 (15%)
Query: 255 CRSGTSVGKVTATDLDEPD-TLHTRLKYKILQQIPDHPKH--FSIHPDTGVITTTTPFLD 311
CR G K D + ++ Y+I D P + F I+ TG I T+ +D
Sbjct: 58 CREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITS-IVD 116
Query: 312 REKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN-RIDV 370
RE + + + GQ L + + + D NDNPP F+ ++ ++EEN +
Sbjct: 117 REVTPFFIIYCRALNSMGQD--LERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANT 174
Query: 371 EILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQV 430
++ + D D PN +SK +KI++ + + + + NT E ++ +N ++R+
Sbjct: 175 LVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGE-----IRTMNNFLDREQ 229
Query: 431 ILQVGVINEAQFSKAASSQTPTMCTTTVTVKIID-SDEGPECHPPVKVIQSQDGFPAGQE 489
Q + + C + KI+D +D P I+ Q+
Sbjct: 230 YGQYALAVRGSDRDGGADGMSAECECNI--KILDVNDNIPYMEQSSYTIEIQEN-TLNSN 286
Query: 490 LLGYKA--LDPEISSG-EGLRYQKLGDEDNWFEI--NQHT--GDLRTLKVLDRE------ 536
LL + LD E S+ + + G+E NWFEI N+ T G L+ +K LD E
Sbjct: 287 LLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQ 346
Query: 537 -SKFVKNN-QYNISVVAVDAVGRSCTGTLVVHLDDYNDHAPQIDKEVTICQN---NEDFA 591
S V+N +++ S+++ + S V+++ + P K + N N+
Sbjct: 347 LSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPG-SKTYVVTGNMGSNDKVG 405
Query: 592 VLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQNLDYN-----YYSVPI 646
D D ++ + N+ + ++ + GK + + YN Y +
Sbjct: 406 DFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTIL 465
Query: 647 QIKDRHGLVATHMLTVRVC----DCSTPSECRMK----------------DKSTRD---- 682
I D T + + + D T +E K D ST
Sbjct: 466 SIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSS 525
Query: 683 --------------VRPNVILGRWAILAMVLGSVLLLCILFT---CFCVTAKRTVKKCFP 725
+ NV G I +++G ++L + F C C A R+ P
Sbjct: 526 QVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEP 585
Query: 726 EDIAQQNLIVS-NTEGPGEE---VTEANIRLPMQTSNICDTSMSVGTVGGQGIKTQQSFE 781
I S EGP E +T ++P +NI + + G+ T +
Sbjct: 586 VPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIEC------IDNSGVYTNEY-- 637
Query: 782 MVKGGYTLDSNKGG----GHQTLESVKGVGQ--------GDTGRYAYTDWQ------SFT 823
GG + GG G + E VK G G R + + + +F
Sbjct: 638 ---GGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFM 694
Query: 824 QPRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPK 883
+ +K Y ++E + D + Y+ EG GS AGSVGCCS E+ FLD L PK
Sbjct: 695 ESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPK 754
Query: 884 FRTLAKTCIKK 894
F+ LA + K
Sbjct: 755 FKKLADISLGK 765
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,548,473
Number of Sequences: 37866
Number of extensions: 1753430
Number of successful extensions: 7173
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3945
Number of HSP's gapped (non-prelim): 870
length of query: 894
length of database: 18,247,518
effective HSP length: 111
effective length of query: 783
effective length of database: 14,044,392
effective search space: 10996758936
effective search space used: 10996758936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.