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Search of human proteins with 55953135
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953135 immunoglobulin superfamily, member 3 isoform 2
[Homo sapiens]
(1194 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo... 2416 0.0
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo... 2403 0.0
gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m... 686 0.0
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens] 629 e-180
gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] 288 3e-77
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s... 251 2e-66
gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m... 240 7e-63
gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens] 240 7e-63
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 67 1e-10
gi|31377806 polymeric immunoglobulin receptor precursor [Homo sa... 50 1e-05
gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens] 46 2e-04
gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo sapi... 46 2e-04
gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens] 45 3e-04
gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo ... 43 0.002
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 43 0.002
gi|110349719 titin isoform N2-A [Homo sapiens] 43 0.002
gi|14150145 matrix-remodelling associated 8 [Homo sapiens] 42 0.003
gi|45331217 zinc finger protein 526 [Homo sapiens] 42 0.005
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 41 0.006
gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.008
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu... 40 0.010
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu... 40 0.010
gi|51988914 fibroblast growth factor receptor-like 1 precursor [... 40 0.010
gi|51988910 fibroblast growth factor receptor-like 1 precursor [... 40 0.010
gi|51988912 fibroblast growth factor receptor-like 1 precursor [... 40 0.010
gi|7662316 HIV-1 Vpr binding protein [Homo sapiens] 40 0.013
gi|21735415 centromere protein B [Homo sapiens] 40 0.013
gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 40 0.013
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 40 0.017
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 40 0.017
>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
sapiens]
Length = 1194
Score = 2416 bits (6262), Expect = 0.0
Identities = 1194/1194 (100%), Positives = 1194/1194 (100%)
Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60
MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY
Sbjct: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60
Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120
LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC
Sbjct: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120
Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180
HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS
Sbjct: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180
Query: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240
VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD
Sbjct: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240
Query: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300
QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF
Sbjct: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300
Query: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360
RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV
Sbjct: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360
Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNAS 420
LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNAS
Sbjct: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNAS 420
Query: 421 VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSS 480
VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSS
Sbjct: 421 VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSS 480
Query: 481 FGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITA 540
FGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITA
Sbjct: 481 FGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITA 540
Query: 541 LEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTR 600
LEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTR
Sbjct: 541 LEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTR 600
Query: 601 DGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTR 660
DGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTR
Sbjct: 601 DGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTR 660
Query: 661 LAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVH 720
LAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVH
Sbjct: 661 LAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVH 720
Query: 721 KPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSY 780
KPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSY
Sbjct: 721 KPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSY 780
Query: 781 YCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV 840
YCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV
Sbjct: 781 YCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV 840
Query: 841 LNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGV 900
LNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGV
Sbjct: 841 LNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGV 900
Query: 901 YRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVP 960
YRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVP
Sbjct: 901 YRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVP 960
Query: 961 NATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEED 1020
NATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEED
Sbjct: 961 NATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEED 1020
Query: 1021 DDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSC 1080
DDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSC
Sbjct: 1021 DDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSC 1080
Query: 1081 HVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGIL 1140
HVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGIL
Sbjct: 1081 HVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGIL 1140
Query: 1141 IITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID 1194
IITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID
Sbjct: 1141 IITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTCLEPPVLSIHPGAID 1194
>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
sapiens]
Length = 1214
Score = 2403 bits (6227), Expect = 0.0
Identities = 1193/1214 (98%), Positives = 1194/1214 (98%), Gaps = 20/1214 (1%)
Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60
MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY
Sbjct: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60
Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120
LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC
Sbjct: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120
Query: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180
HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS
Sbjct: 121 HTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180
Query: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240
VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD
Sbjct: 181 VAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSD 240
Query: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300
QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF
Sbjct: 241 QGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEF 300
Query: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360
RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV
Sbjct: 301 RCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFV 360
Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPL------------- 407
LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPL
Sbjct: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQ 420
Query: 408 -------KSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 460
+SSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI
Sbjct: 421 LLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNI 480
Query: 461 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 520
MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV
Sbjct: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAV 540
Query: 521 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 580
DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV
Sbjct: 541 DGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSV 600
Query: 581 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 640
TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA
Sbjct: 601 TWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEA 660
Query: 641 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 700
GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN
Sbjct: 661 GKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLN 720
Query: 701 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 760
CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV
Sbjct: 721 CSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780
Query: 761 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 820
SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS
Sbjct: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLS 840
Query: 821 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 880
QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE
Sbjct: 841 QAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGE 900
Query: 881 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 940
QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG
Sbjct: 901 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 960
Query: 941 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1000
QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK
Sbjct: 961 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGK 1020
Query: 1001 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1060
RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP
Sbjct: 1021 RSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSP 1080
Query: 1061 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1120
VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC
Sbjct: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIIC 1140
Query: 1121 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1180
SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC
Sbjct: 1141 SNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWIKEPHLNYSPTC 1200
Query: 1181 LEPPVLSIHPGAID 1194
LEPPVLSIHPGAID
Sbjct: 1201 LEPPVLSIHPGAID 1214
>gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 376
Score = 686 bits (1771), Expect = 0.0
Identities = 341/355 (96%), Positives = 345/355 (97%)
Query: 187 KVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 246
KVGEKPVEVISLSRDFMLHS SEYA RQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC
Sbjct: 20 KVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 79
Query: 247 EAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEA 306
EAAEWIQ+PDGSWYAMTRKRSEGAVVNVQPT+KEFTVRLETEKRLH VGEPVEFRCI EA
Sbjct: 80 EAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEA 139
Query: 307 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHL 366
QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL VAKESDSVFVLKIYHL
Sbjct: 140 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199
Query: 367 RQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGE 426
RQEDSGKYNCRVTEREKTVTGEFIDKESK PKNIPIIVLPL+SSISVEVASNASVILEGE
Sbjct: 200 RQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGE 259
Query: 427 DLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQM 486
DLRFSCSVR AGRPQGRFSVIWQLVDRQNRRS+IMWLDRDGTVQPGSSYWERSSFG VQM
Sbjct: 260 DLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQM 319
Query: 487 EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITAL 541
EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR VDGEWQIVGERRASTPISI AL
Sbjct: 320 EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
Score = 99.0 bits (245), Expect = 2e-20
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 42/350 (12%)
Query: 765 FSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQG 824
F LT+ + SD G +YC EW+ +P+ +WY + + S V V+ + +
Sbjct: 62 FRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETE 121
Query: 825 NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAK 884
+ V+ C+ + V W +A + +A + A
Sbjct: 122 KRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF------NSSLIATMGPNAVPVLNSEFAH 175
Query: 885 NNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTAL 944
+G+L++ S V+ L I ++ +DSG Y+C V E + +G + + +
Sbjct: 176 REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPI 235
Query: 945 TVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSP 1004
V+ ++S+ V+ + + E + CS+ RF+V W +
Sbjct: 236 IVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLV----------- 284
Query: 1005 GLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWE----GRLRFQRLSP 1060
D R+ ++ + D P S WE G ++ +++ P
Sbjct: 285 --------------------DRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQP 324
Query: 1061 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE-SAPIGIRVL 1109
+ L + + +D G Y CHV EW+ EW + E S PI I L
Sbjct: 325 NSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
Score = 98.2 bits (243), Expect = 4e-20
Identities = 82/342 (23%), Positives = 146/342 (42%), Gaps = 30/342 (8%)
Query: 84 YTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMN----- 138
Y R G++ ++++ + L I LQ D GE+ C + GS+ A
Sbjct: 43 YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102
Query: 139 --LVVIPDSLQTTAMPQTLHRVEQ--DPLELTCEVASETIQHSHLSVAW-----LRQKVG 189
+ V P + T +T R+ +P+E C ++ + + +V+W L +G
Sbjct: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMG 162
Query: 190 EKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAA 249
V V+ +SE+A R++ G++ + K + F L I+HL+ D G++ C
Sbjct: 163 PNAVPVL----------NSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVT 212
Query: 250 EWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309
E + G + K + + V P + +V + + + GE + F C +
Sbjct: 213 EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGR 272
Query: 310 PDRYFAVSWAF-----NSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIY 364
P F+V W S I + + S + R + G +++ + + F L I+
Sbjct: 273 PQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332
Query: 365 HLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVL 405
+ R+ED G+Y C VTE + V GE+ I E + I II L
Sbjct: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
Score = 92.4 bits (228), Expect = 2e-18
Identities = 77/348 (22%), Positives = 144/348 (41%), Gaps = 20/348 (5%)
Query: 460 IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRA 519
++ L RD + GS Y R S G V+++++ +F L IF+ + D+G++ C EW++
Sbjct: 28 VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
Query: 520 VDGEWQIVGERRAS-TPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 578
DG W + +R+ +++ E F V + + + +CI +
Sbjct: 88 PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYF 147
Query: 579 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFR-TRTAIEKAESSNNVR-LSISRAS 636
+V+W F L+ V + + R R + A+ S++V L I
Sbjct: 148 AVSWAFNS-------SLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLR 200
Query: 637 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 696
++GKY C K + + + I VL + + V + ++E +
Sbjct: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260
Query: 697 IQLNCSVKSQTSQNSHFAVLWYV----HKPSDADGKLILKTTHNSAFEYGTYAEEEGLRA 752
++ +CSV+ F+V+W + ++ SD I+ + + G+ E
Sbjct: 261 LRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSD-----IMWLDRDGTVQPGSSYWERSSFG 315
Query: 753 RLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAE 800
+Q E+ V FSL + + D G Y CHV EW+ + W + E
Sbjct: 316 SVQMEQ-VQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGE 362
Score = 81.3 bits (199), Expect = 5e-15
Identities = 72/307 (23%), Positives = 120/307 (39%), Gaps = 16/307 (5%)
Query: 629 RLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTK---LQVSKS 685
RL+I ++ G++ C A W +N + +W + + S + V QP K +++
Sbjct: 63 RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNV-QPTEKEFTVRLETE 121
Query: 686 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYA 745
KR + E P++ C ++Q + +FAV W + LI N+ +
Sbjct: 122 KRLHMVGE--PVEFRCIPEAQNVPDRYFAVSWAFNS------SLIATMGPNAVPVLNSEF 173
Query: 746 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 805
R +L + S +F L + DSG Y C V E + + +
Sbjct: 174 AHREARGQLNVAKE-SDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
Query: 806 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNHPER 864
+ V +S + + A +LE ++ C V + V W V + N R
Sbjct: 233 IPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNR--R 290
Query: 865 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 924
+ L RD T G + + G + +E P + L I N +D G Y CHV EW+
Sbjct: 291 SDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 350
Query: 925 PSPSGMW 931
G W
Sbjct: 351 RVVDGEW 357
Score = 57.4 bits (137), Expect = 8e-08
Identities = 59/262 (22%), Positives = 96/262 (36%), Gaps = 44/262 (16%)
Query: 867 VARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPS 926
V LSRD H G + A G + L+ +RL I ++ D G + C EW+ +
Sbjct: 28 VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
Query: 927 PSGMWY----KRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQ 982
P G WY KR+E T + +++++T V E F+ C +++
Sbjct: 88 PDGSWYAMTRKRSEGAVVNVQPT--EKEFTVRLETEKRLHMVGEPVEFR--CIPEAQNVP 143
Query: 983 DSRFAVAW--YSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDA 1040
D FAV+W S G + P L + RE
Sbjct: 144 DRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREA------------------------- 178
Query: 1041 VFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE 1100
G+L + S ++ L + +D+G Y+C V E + E+ +
Sbjct: 179 ---------RGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKH 229
Query: 1101 SAPIGIRVLDTSPTLQSIICSN 1122
I I VL ++ + SN
Sbjct: 230 PKNIPIIVLPLESSISVEVASN 251
Score = 35.8 bits (81), Expect = 0.25
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 34 EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 92
EG + C+V P + + W + + ++ + + P + Y +R G
Sbjct: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316
Query: 93 IFIERVQGNSTLLHITDLQARDAGEYECH 121
+ +E+VQ NS L I + + D G+YECH
Sbjct: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345
>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
Length = 1021
Score = 629 bits (1621), Expect = e-180
Identities = 366/961 (38%), Positives = 549/961 (57%), Gaps = 36/961 (3%)
Query: 4 FFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPS 63
FF +L+ L++ QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP+
Sbjct: 10 FFLLLTKLSI-----GQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123
+P +EVQI+ST D++F YA+YTQRVR G +++ERVQGNS LLHI+ LQ +DAGEYECHTP
Sbjct: 65 NPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTP 124
Query: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183
+TD++Y+GSYSAK NL+VIPD+L T QTL + E +PL LTCE + T QH+HLSV W
Sbjct: 125 NTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184
Query: 184 --LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQ 241
+ G + E+ISLS+DF+L Y +R + +V+L+KLG TTFRL+I LQ SDQ
Sbjct: 185 YLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQ 244
Query: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301
G+ +CEA EWIQDPD +W +T+K+++ + +QP K+F V + T L G+P+E
Sbjct: 245 GQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELV 303
Query: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
C++ + D W FN + IA + V L +++ R ++G+L+V+K F L
Sbjct: 304 CLVVSSG-RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSL 362
Query: 362 KIYHLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVLPLKSSISVEVASNAS 420
KI+ L ED G Y C V E KT TG + + + + P + + P S+ + +
Sbjct: 363 KIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQ 422
Query: 421 VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR-QNRRSNIMWLDRDGTVQPGSSYWERS 479
V+ EGE L F C AG + SV W + R Q + + + +DG VQ G+SY S
Sbjct: 423 VVWEGETLAFLCK---AGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPS 479
Query: 480 SFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR--AVDGEWQIVGERRASTPIS 537
G ++E++ +F L I + D G YEC V+E R A D W ++
Sbjct: 480 YHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSW------TQKISVT 533
Query: 538 ITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHY-PAWVPVSVTWRFQPVGTVEFHDLV 596
+ +LE V+ +SR P V +++FDL C+++ Y VP++VTW+FQP + FH L+
Sbjct: 534 VKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLI 593
Query: 597 TFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKN--Y 654
T +G ++WG+ S F+ +T + ++S +L + A++ E G YQC E++ +N Y
Sbjct: 594 RITHNGTIEWGNFLSRFQKKTKV--SQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLY 651
Query: 655 NNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFA 714
NN R A S+ L I V P +KL+V+ + L N + CS+ S+++ N A
Sbjct: 652 NNRPPR-ASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLA 710
Query: 715 VLWYVHKPS-DADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAE 773
++WY S +A IL+ + + G + + E+ VS LF L + E
Sbjct: 711 IIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEK-VSQDLFQLHILNVE 769
Query: 774 VSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQ 833
SD G Y+C VEEWLLS N W+KL E+ SG TE+ +K S++R+S+ +V E R+
Sbjct: 770 DSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHRE 829
Query: 834 VQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHL 893
V + C + + S + V W+ W + + + L D YGE+ L+ LH
Sbjct: 830 VAIRCSLESVGSSATLYSVMWY-WNRENSGSKLLVHLQHDGLLEYGEE----GLRRHLHC 884
Query: 894 ESPSPGVYRLFIQNVAVQDSGTYSCHVEEW-LPSPSGMWYKRAEDTAGQTALTVMRPDAS 952
S + L + V ++D+G Y C V EW L W +A D + + LTV+ + +
Sbjct: 885 YRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPT 944
Query: 953 L 953
L
Sbjct: 945 L 945
Score = 267 bits (682), Expect = 5e-71
Identities = 276/1070 (25%), Positives = 448/1070 (41%), Gaps = 107/1070 (10%)
Query: 132 SYSAKMNLVVIPDSL---QTTAMPQTLHRVEQDPLELTCEVASE---TIQHSHLSVAWLR 185
SY A L++ S+ + T L R E P+ + C V + QH SV
Sbjct: 5 SYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
Query: 186 QKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 245
E V++IS ++D S + Y QR G+V ++++ + L I LQ D GE+
Sbjct: 65 NPTQE--VQIIS-TKDAAF-SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
Query: 246 CEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILE 305
C + GS+ A T + V P T+ +T + GEP+ C
Sbjct: 121 CHTPNTDEKYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEAS 171
Query: 306 AQNVPDRYFAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSV 358
+ +V+W ++ I ++ + + V + R A +++ K +
Sbjct: 172 KATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTT 231
Query: 359 FVLKIYHLRQEDSGKYNCRVTE--REKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVA 416
F L I L+ D G+ C TE ++ T FI K K+ + + P V +
Sbjct: 232 FRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNIT 289
Query: 417 SNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYW 476
++ S+ EG+ L C V ++GR + IW + I +D G + + Y
Sbjct: 290 AD-SLFAEGKPLELVCLVVSSGRDP-QLQGIWFF-----NGTEIAHIDAGGVLGLKNDYK 342
Query: 477 ERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPI 536
ER+S G +Q+ ++ P +FSL IF+ EDEG Y C V E ++ G WQ++ +R +P
Sbjct: 343 ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVL--QRKQSPD 400
Query: 537 SITALEMGFAVTAISRTPG----VTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEF 592
S L A + + T V ++ C A P+SV+W P +
Sbjct: 401 SHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGG---AESPLSVSWWHIPRDQTQP 457
Query: 593 HDLVTFTRDGGVQWGDRSS--SFRTRTAIEKAESSNNVRLSISRASDTEAGKYQC-VAEL 649
+ +DG VQ G S+ T +EK + + +L I+ + T++G Y+C V+E
Sbjct: 458 EFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWAT-FQLEITFTAITDSGTYECRVSEK 516
Query: 650 WRKNYNN-TWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTS 708
R + +WT+ T LE + LQVS R ++ L+C V++ S
Sbjct: 517 SRNQARDLSWTQKISVTVKSLE-------SSLQVSLMSRQPQVMLTNTFDLSCVVRAGYS 569
Query: 709 Q-NSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLF-- 765
V W S +++ THN E+G + +R Q + VS LF
Sbjct: 570 DLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFL------SRFQKKTKVSQSLFRS 623
Query: 766 SLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYK-LAEEVSGRTEVTVKQPDSRLRLSQAQG 824
L V A ++G Y C VE + + Y A +S + V P+S+L+++
Sbjct: 624 QLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQ 683
Query: 825 NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDAT--FHYGEQA 882
+ +EC +L+R++ QL + W+ + P + L D T G++
Sbjct: 684 VQELSINSNTDIECSILSRSNGNLQLAIIWY-FSPVSTNASWLKILEMDQTNVIKTGDEF 742
Query: 883 AKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQT 942
K + H E S +++L I NV D G Y C VEEWL S +G W+K E +G T
Sbjct: 743 HTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLT 802
Query: 943 ALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRS 1002
L + + ++V V V+E + CS+ S S + ++V WY R +G K
Sbjct: 803 ELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRENSGSK-- 860
Query: 1003 SPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAV--FGPEGSPWEGRLRFQRLSP 1060
L+ + D + +G EG L R S
Sbjct: 861 -----------------------------LLVHLQHDGLLEYGEEG--LRRHLHCYRSSS 889
Query: 1061 VLYRLTVLQASPQDTGNYSCHVEEW-LPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSII 1119
+ L + Q +D G Y C V EW L +W +ES + + VL + PTL S I
Sbjct: 890 TDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRI 949
Query: 1120 CSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWI 1169
CS+ L YF+F PF + +L+I++L + +K+R S LW+
Sbjct: 950 CSSAPLLYFLFICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWV 999
>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
Length = 613
Score = 288 bits (736), Expect = 3e-77
Identities = 186/564 (32%), Positives = 283/564 (50%), Gaps = 41/564 (7%)
Query: 8 LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPER 67
L L +LG+ R+V V EGPLYR G+ ++I CNV+GY+GP++QNF+W +Y P +P+
Sbjct: 15 LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
Query: 68 EVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDK 127
+ IVST D+ F YA++ RV G++ ++R+QG++ +L I LQA+DAG YECHTPSTD
Sbjct: 75 ALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDT 134
Query: 128 QYFGSYSAKMNLVVIPDSLQTTAMP--------------QTLHRVEQDPLELTCEVASET 173
+Y GSYS K+ L V+PD LQ +A P T+H E L L C + T
Sbjct: 135 RYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVH--EGQELALGCLARTST 192
Query: 174 IQHSHLSVAWLRQKVGEKPV------EVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRT 227
+H+HL+V++ R V E PV EV+ + D + + + YA+R + GE+RL K G
Sbjct: 193 QKHTHLAVSFGR-SVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251
Query: 228 TFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLET 287
+R+ + Q D G ++C AAEWIQDPDGSW + KR+ A V+VQ + V +
Sbjct: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
Query: 288 EKRLHTVGEPVEFRCILEAQNVP-DRYFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREA 345
+R GEP+E C + P R+ A S + + GP V L++E
Sbjct: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371
Query: 346 RG----QLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIP 401
G + + K + + L++ R D+G Y C + + S R + +P
Sbjct: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431
Query: 402 IIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQG-RFSVIWQLVDRQNRRSN- 459
+ V + + GE C++ G P G R + W + ++ +
Sbjct: 432 VHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSS 491
Query: 460 -----IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 514
+ + +DG + G R G V +E V P S L + + EDEG Y C +
Sbjct: 492 VPAQLVGGVGQDGVAELG----VRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPS 547
Query: 515 EWVRAVDGEWQIVGERRASTPISI 538
WV+ D W G R S P+++
Sbjct: 548 AWVQHADYSWYQAGSAR-SGPVTV 570
Score = 95.1 bits (235), Expect = 3e-19
Identities = 109/499 (21%), Positives = 188/499 (37%), Gaps = 58/499 (11%)
Query: 628 VRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKL------- 680
V L I+R +AG Y+C + +T TR S +E+RVL V ++
Sbjct: 110 VVLKIARLQAQDAGIYEC-------HTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGP 162
Query: 681 ---QVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTT--- 734
Q S +T+ E + + L C ++ T +++H AV + P G+ L+
Sbjct: 163 RGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGI 222
Query: 735 -HNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 793
+ A E G E L+ + + + + V A+ D+G+Y+C EW+ P+
Sbjct: 223 RSDLAVEAGAPYAERLAAGELRLGKEGTDR-YRMVVGGAQAGDAGTYHCTAAEWIQDPDG 281
Query: 794 AWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSITSQL 850
+W ++AE+ + V V+ S+L ++ G + ++L C V L +
Sbjct: 282 SWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAY 341
Query: 851 MVEWFVWKPNHP-ERETVARLSRDATFHYGEQAAKNNLKGR-LHLESPSPGVYRLFIQNV 908
V W + P VA+L + G +GR + +E + YRL ++
Sbjct: 342 SVGWEMAPAGAPGPGRLVAQLDTEGVGSLGP-----GYEGRHIAMEKVASRTYRLRLEAA 396
Query: 909 AVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKA 968
D+GTY C + ++ + A + + V L+ + TV
Sbjct: 397 RPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGE 456
Query: 969 AFQLDCSIVSRSSQDS-RFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDP 1027
L C+I R R A +W+ R + G S P
Sbjct: 457 TASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPA---------------------- 494
Query: 1028 TERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLP 1087
+ VG D V P G + + + P +RL + P+D G Y C W+
Sbjct: 495 ---QLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQ 551
Query: 1088 SPQKEWYRLTEEESAPIGI 1106
WY+ S P+ +
Sbjct: 552 HADYSWYQAGSARSGPVTV 570
Score = 81.6 bits (200), Expect = 4e-15
Identities = 89/441 (20%), Positives = 166/441 (37%), Gaps = 50/441 (11%)
Query: 692 VENKPIQLNCSV---KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEE 748
V + ++C+V + QN W++++P D L + +T ++ F Y + +
Sbjct: 40 VAGTAVSISCNVTGYEGPAQQNFE----WFLYRPEAPDTALGIVSTKDTQFSYAVF-KSR 94
Query: 749 GLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE--EWLLSPNYAWYKLAEEVSGRT 806
+ +Q +R + G L + R + D+G Y CH + +Y+ +
Sbjct: 95 VVAGEVQVQR-LQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVL 153
Query: 807 EVTVKQPDSRLRLSQAQG-NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP--- 862
+V+ P R R + ++V E +++ L C+ T + L V + P P
Sbjct: 154 QVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGR 213
Query: 863 -ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVE 921
+ V + D G A+ G L L YR+ + D+GTY C
Sbjct: 214 STLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAA 273
Query: 922 EWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI---VS 978
EW+ P G W + AE A + V + L V + +L C++ +
Sbjct: 274 EWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333
Query: 979 RSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGP 1038
+ + + ++V W A G PG + + E + S+GP
Sbjct: 334 PAGRHAAYSVGWEMAPAGAPG----PGRLVAQLDTE-----------------GVGSLGP 372
Query: 1039 DAVFGPEGSPWEGR-LRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLT 1097
+EGR + ++++ YRL + A P D G Y C + ++
Sbjct: 373 G---------YEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA 423
Query: 1098 EEESAPIGIRVLDTSPTLQSI 1118
S P+ + V + L+++
Sbjct: 424 SARSRPLPVHVREEGVVLEAV 444
Score = 80.5 bits (197), Expect = 9e-15
Identities = 97/485 (20%), Positives = 193/485 (39%), Gaps = 42/485 (8%)
Query: 482 GGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV----TEWVRAVDGEWQIVGERRASTPIS 537
G VQ++++Q ++ L I + +D G YECH T ++ + G+ ++ R +
Sbjct: 98 GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVEL---RVLPDVLQ 154
Query: 538 ITALEMG-FAVTAISRTPGVTYSDSFDLQ--CIIKPHYPAWVPVSVTWRFQ----PVGTV 590
++A G A + P +T + +L C+ + ++V++ PVG
Sbjct: 155 VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214
Query: 591 EFHDLVTFTRD----GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 646
++V D G + +R ++ R E ++ R+ + A +AG Y C
Sbjct: 215 TLQEVVGIRSDLAVEAGAPYAERLAAGELRLG---KEGTDRYRMVVGGAQAGDAGTYHCT 271
Query: 647 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKS- 705
A W ++ + +W ++AE+ + L + V ++L V+ + +P++L C+V
Sbjct: 272 AAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGA 331
Query: 706 --QTSQNSHFAVLWYVHKPSDA--DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVS 761
+++ ++V W + P+ A G+L+ + G G R V+
Sbjct: 332 LPPAGRHAAYSVGWEM-APAGAPGPGRLVAQLDTEGVGSLG-----PGYEGRHIAMEKVA 385
Query: 762 GGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQ 821
+ L ++ A D+G+Y C + ++ + A S V V++ L
Sbjct: 386 SRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVA 445
Query: 822 AQGNLSVLETRQVQLECVVLNRTSITS-QLMVEWFVWKPNHPE-----RETVARLSRDAT 875
+V L C + R +L W+V +P E + V + +D
Sbjct: 446 WLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGV 505
Query: 876 FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRA 935
G + G + +E P +RL + ++ +D G Y C W+ WY+
Sbjct: 506 AELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAG 561
Query: 936 EDTAG 940
+G
Sbjct: 562 SARSG 566
>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
sapiens]
Length = 879
Score = 251 bits (642), Expect = 2e-66
Identities = 219/840 (26%), Positives = 365/840 (43%), Gaps = 59/840 (7%)
Query: 6 PVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65
P+L L L + R V V L R G+ + I CNVS Y GPSEQNF WS S
Sbjct: 8 PLLLALLSLALCRG-RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLG 64
Query: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPST 125
V++ ST + FP +Y +R++ G+I + R ++ LHI ++Q D G Y+C TPST
Sbjct: 65 SSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPST 124
Query: 126 DKQYFGSYSAKMNLVVIPDSLQ---TTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVA 182
D G+Y + + V+ DSL + P +L E +P EL C AS + H+HL++
Sbjct: 125 DATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALL 184
Query: 183 WLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQG 242
W + G V++L+ + H Y QR G+VRLD +G +RL++ +DQG
Sbjct: 185 WEVHR-GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQG 243
Query: 243 EFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTV-GEPVEFR 301
+ C +EWI + G+W + K E A V +QP+ +R K + G+ ++
Sbjct: 244 SYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLT 298
Query: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
C + D V+W+F+ +T+ + V + + + ++ + L
Sbjct: 299 CNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHL 358
Query: 362 KIYHLRQEDSGKYNCRVT--EREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNA 419
+ + +E+SG Y C V+ + + + P + + L +V NA
Sbjct: 359 LVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWL----EPDYQVYLNA 414
Query: 420 SVI--LEGEDLRFSCSV--RTAGRPQGRFSVIWQLVDRQNRRSN-------IMWLDRDGT 468
S + + +C V +G RF+V W R NRRS+ + +D D T
Sbjct: 415 SKVPGFADDPTELACRVVDTKSGEANVRFTVSWYY--RMNRRSDNVVTSELLAVMDGDWT 472
Query: 469 VQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVG 528
++ G +R+ G + ++F+ I + +ED G Y C V+ W + + W +
Sbjct: 473 LKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSW-VKS 531
Query: 529 ERRASTPISI-TALEMG-FAVTAISRTPGVTYSDSFDLQC------IIKPHYPAWVPVSV 580
+ S P++I ALE V A P ++F++ C I P Y +
Sbjct: 532 KDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAE- 590
Query: 581 TWRFQPVGTV----EFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRAS 636
+PVG + E +++ +D V+ + + + R + + + R + +
Sbjct: 591 ----KPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQ 646
Query: 637 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 696
++AG Y+C+ W + W A SN +EI S T +++
Sbjct: 647 VSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDL 706
Query: 697 IQLNCSVKSQTS----QNSHFAVLWY-VHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 751
I+L C + + + + F V W+ VH ++L + +
Sbjct: 707 IKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGI---VTTSRRDWK 763
Query: 752 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVK 811
+ L ER VS F L V +E D G+YYC V W+ SP +W K AE S +TVK
Sbjct: 764 SDLSLER-VSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVK 822
Score = 184 bits (467), Expect = 4e-46
Identities = 182/848 (21%), Positives = 317/848 (37%), Gaps = 72/848 (8%)
Query: 283 VRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 339
VR+ T + VG + C + + P W+F+S S + V
Sbjct: 24 VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82
Query: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399
+ R RG++ + + ++ L I +++ D G Y C + TV G + D
Sbjct: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYED-------T 135
Query: 400 IPIIVLPLKSSISVEVASNASVIL-EGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRS 458
+ + VL + S+ L EGE C+ +A +++W+ V R R
Sbjct: 136 VQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARR 194
Query: 459 NIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR 518
+++ L +G PG Y +R G V+++ V +++ L + + D+G Y C V+EW+
Sbjct: 195 SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI- 253
Query: 519 AVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 578
A G WQ + E+ + ++ ++ A+ + V DL C I V
Sbjct: 254 AEQGNWQEIQEK--AVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRP 311
Query: 579 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAE-SSNNVRLSISRASD 637
VTW F + R DR S + + + + + L + S
Sbjct: 312 EVTWSFSRMPDSTLPGSRVLARL------DRDSLVHSSPHVALSHVDARSYHLLVRDVSK 365
Query: 638 TEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRV--LQPVTKLQVSKSKRTLTLVENK 695
+G Y C LW +N +W ++AE S+ + V L+P ++ ++ SK + +
Sbjct: 366 ENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASK--VPGFADD 423
Query: 696 PIQLNCSVKSQTS--QNSHFAVLWYVHKPSDADG----KLILKTTHNSAFEYGTYAEEEG 749
P +L C V S N F V WY +D +L+ + +YG +++
Sbjct: 424 PTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRA 483
Query: 750 LRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVT 809
F + + F+ +QR D G+YYC V W N +W K + S +
Sbjct: 484 QDGDFIFSKEHTD-TFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIF 542
Query: 810 VKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKP-----NHPER 864
DS L + Q ++ C V ++ + + V KP + E
Sbjct: 543 WALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNET 602
Query: 865 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 924
+ + L +D+ + + G + LE +R + V D+G Y C V W
Sbjct: 603 KYIISLDQDSVVKLENWTDASRVDGVV-LEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWS 661
Query: 925 PSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSS--- 981
P +W + A + + +V +L C I +
Sbjct: 662 PVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALD 721
Query: 982 -QDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDA 1040
D F V+W+++ S GL++ L S+
Sbjct: 722 PDDMAFDVSWFAVH--------SFGLDKAP--------------------VLLSSLDRKG 753
Query: 1041 VFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE 1100
+ W+ L +R+S + + L V + QD GNY C V W+ SP W + E
Sbjct: 754 IVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIH 813
Query: 1101 SAPIGIRV 1108
S P+ I V
Sbjct: 814 SKPVFITV 821
Score = 159 bits (401), Expect = 2e-38
Identities = 192/821 (23%), Positives = 316/821 (38%), Gaps = 57/821 (6%)
Query: 154 TLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR 213
TL RV L + C V S+ S + W +G VE+ S + + Y +R
Sbjct: 30 TLVRVVGTELVIPCNV-SDYDGPSEQNFDWSFSSLGSSFVELASTWE--VGFPAQLYQER 86
Query: 214 QSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVN 273
GE+ L + L I ++QPSDQG + C G++ + + ++
Sbjct: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
Query: 274 VQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSW------AFNSSLIAT 327
V P+ + E GEP E RC + + + A+ W A S L T
Sbjct: 147 VGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALT 200
Query: 328 MGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTG 387
P L E R G +++ + L + D G Y C V+E G
Sbjct: 201 HEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE-QG 257
Query: 388 EFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVI 447
+ + + K + +++ P S + V N SV EG++L +C++ T R V
Sbjct: 258 NWQEIQEKAVEVATVVIQP--SVLRAAVPKNVSVA-EGKELDLTCNITTDRADDVRPEVT 314
Query: 448 W---QLVDRQNRRSNIMW-LDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRK 503
W ++ D S ++ LDRD V S V + V S+ L + + K
Sbjct: 315 WSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPHVALSHVDARSYHLLVRDVSK 365
Query: 504 EDEGQYECHVTEWVRAVDGEWQIVGERRASTP-ISITALEMGFAVTA-ISRTPGVTYSDS 561
E+ G Y CHV+ W + W V E +S + +T LE + V S+ PG D
Sbjct: 366 ENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFA-DDP 424
Query: 562 FDLQCII--KPHYPAWVPVSVTWRFQ----PVGTVEFHDLVTFTRDGGVQWGDRSSS-FR 614
+L C + A V +V+W ++ V L D +++G+RS +
Sbjct: 425 TELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQ 484
Query: 615 TRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVL 674
I E ++ I R ++ + G Y CV W K NN+W + + S + I
Sbjct: 485 DGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWA 544
Query: 675 QPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKP-----SDADGKL 729
+ L V + ++ C V S+ ++ ++VL KP S + K
Sbjct: 545 LEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNETKY 604
Query: 730 ILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLL 789
I+ +S + + + + + V F + + +VSD+G Y C V W
Sbjct: 605 IISLDQDSVVKLENWTDASRVDGVVL--EKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSP 662
Query: 790 SPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV-LNRTSITS 848
W + A +S E+ + S SV+ ++L C++ + ++
Sbjct: 663 VRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALDP 722
Query: 849 QLM---VEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFI 905
M V WF ++ V S D ++ + K L LE S + L +
Sbjct: 723 DDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIV--TTSRRDWKSDLSLERVSVLEFLLQV 780
Query: 906 QNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTV 946
QD G Y C V W+ SP+G W K AE + +TV
Sbjct: 781 HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITV 821
Score = 135 bits (341), Expect = 2e-31
Identities = 154/753 (20%), Positives = 276/753 (36%), Gaps = 84/753 (11%)
Query: 394 SKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR 453
+ RP + ++ L L V V + V + G +L C+V P + + W
Sbjct: 5 ASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSF--- 60
Query: 454 QNRRSNIMWLDRDGTVQ-PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 512
+ S+ + L V P Y ER G + + + ++ L I N + D+G Y+C
Sbjct: 61 SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
Query: 513 VTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTP---GVTYSDSFDLQCIIK 569
V G ++ + + L V +R P + + F+L+C
Sbjct: 121 TPSTDATVQGNYE--------DTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAA 172
Query: 570 PHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDG----GVQWGDRSSSFRTRTAIEKAESS 625
P +++ W G ++ T +G G+ + R S R S
Sbjct: 173 SASPLHTHLALLWEVHR-GPAR-RSVLALTHEGRFHPGLGYEQRYHSGDVRL---DTVGS 227
Query: 626 NNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKS 685
+ RLS+SRA + G Y+C+ W N W + E+ + + + V + V K+
Sbjct: 228 DAYRLSVSRALSADQGSYRCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPKN 286
Query: 686 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDAD---GKLILKTTHNSAFEYG 742
+++ E K + L C++ + + + V W + D+ +++ + +S
Sbjct: 287 ---VSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSS 343
Query: 743 TYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEV 802
+ HV + L V+ +SG YYCHV W N +W+K+AE V
Sbjct: 344 PHVALS----------HVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAV 393
Query: 803 SGRTEVTVK--QPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTS--ITSQLMVEWFVWK 858
S V V +PD ++ L+ ++ + +L C V++ S + V W+
Sbjct: 394 SSPAGVGVTWLEPDYQVYLNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRM 451
Query: 859 PNHPER----ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSG 914
+ E +A + D T YGE++ + G + IQ +D G
Sbjct: 452 NRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRG 511
Query: 915 TYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDC 974
Y C V W + W K + + + D+ L V P + F++ C
Sbjct: 512 NYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTC 571
Query: 975 SIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALL 1034
+ S++ + R++V + E+ D P E ++
Sbjct: 572 KVSSKNIKSPRYSVLIMA-------------------------EKPVGDLSSPNETKYII 606
Query: 1035 SVGPDAVFGPEGSPWEGRLR-----FQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSP 1089
S+ D+V E W R +++ +R + Q D G Y C V W P
Sbjct: 607 SLDQDSVVKLEN--WTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVR 664
Query: 1090 QKEWYRLTEEESAPIGIRVLDTSPTLQSIICSN 1122
W S PI I + P + + S+
Sbjct: 665 GSLWREAATSLSNPIEIDFQTSGPIFNASVHSD 697
Score = 135 bits (341), Expect = 2e-31
Identities = 146/656 (22%), Positives = 245/656 (37%), Gaps = 50/656 (7%)
Query: 57 WSIYLPSSPEREVQIVSTMDSSF-PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDA 115
W ++ P R + T + F P Y QR G + ++ V ++ L ++ + D
Sbjct: 185 WEVH--RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQ 242
Query: 116 GEYECHTPST-----DKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVA 170
G Y C + Q + ++ VVI S+ A+P+ + E L+LTC +
Sbjct: 243 GSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNIT 302
Query: 171 SETIQHSHLSVAWLRQKVGEKPVE----VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGR 226
++ V W ++ + + + L RD ++HSS A L +
Sbjct: 303 TDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVA---------LSHVDA 353
Query: 227 TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLE 286
++ L + + + G +YC + W + SW+ + S A V V + ++ V L
Sbjct: 354 RSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLN 413
Query: 287 TEKRLHTVGEPVEFRC--ILEAQNVPDRYFAVSWAFN----------SSLIATMGPNAVP 334
K +P E C + + F VSW + S L+A M +
Sbjct: 414 ASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTL 473
Query: 335 VLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394
R G +KE F +I +ED G Y C V+ K ++ +
Sbjct: 474 KYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKD 533
Query: 395 KRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQL---- 450
K + I S + V+ G +C V + R+SV+
Sbjct: 534 VFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPV 593
Query: 451 --VDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQ 508
+ N I+ LD+D V+ ++ + S GV +E+VQ + F ++ ++ D G
Sbjct: 594 GDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGL 652
Query: 509 YECHVTEWVRAVDGEWQIVGERRASTPISITALEMG--FAVTAISRTPGVTYSDSFDLQC 566
Y C VT W W+ S PI I G F + S TP V D L C
Sbjct: 653 YRCMVTAWSPVRGSLWREAATS-LSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFC 711
Query: 567 IIKPHYPAWVP----VSVTW-RFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEK 621
II A P V+W G + L++ G+ R +++ ++E+
Sbjct: 712 IITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRD-WKSDLSLER 770
Query: 622 AESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPV 677
S L + + D + G Y C W K+ +W + AE S + I V V
Sbjct: 771 V-SVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDV 825
Score = 126 bits (316), Expect = 1e-28
Identities = 131/588 (22%), Positives = 230/588 (39%), Gaps = 60/588 (10%)
Query: 530 RRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPH---YPAWVPVSVTWRFQP 586
R AS P+ + L + + R P T + +I + Y + W F
Sbjct: 3 RLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSS 62
Query: 587 VGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 646
+G+ F +L + T + G + + + +++ V L I ++ G Y+C
Sbjct: 63 LGS-SFVELAS-TWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
Query: 647 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKR---TLTLVENKPIQLNCSV 703
+T + + ++++VL L V S R +L+L E +P +L C+
Sbjct: 121 TP-------STDATVQGNYEDTVQVKVL--ADSLHVGPSARPPPSLSLREGEPFELRCTA 171
Query: 704 KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGG 763
S + ++H A+LW VH+ + +L TH F G E+ ++ + V
Sbjct: 172 ASASPLHTHLALLWEVHRGPAR--RSVLALTHEGRFHPGLGYEQRYHSGDVRLDT-VGSD 228
Query: 764 LFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQ 823
+ L+V RA +D GSY C V EW+ W ++ E+ V ++ R + +
Sbjct: 229 AYRLSVSRALSADQGSYRCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPK-- 285
Query: 824 GNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNH--PERETVARLSRDATFHYGE 880
N+SV E +++ L C + + + V W F P+ P +ARL RD+ H
Sbjct: 286 -NVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP 344
Query: 881 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 940
A +++ R Y L +++V+ ++SG Y CHV W P + W+K AE +
Sbjct: 345 HVALSHVDARS---------YHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSS 395
Query: 941 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDS--RFAVAWYSLRTKAG 998
+ V + QV +L C +V S ++ RF V+WY +
Sbjct: 396 PAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRR- 454
Query: 999 GKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRL 1058
+ E D D ER+ + D +F E +
Sbjct: 455 --------SDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTD---------- 496
Query: 1059 SPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGI 1106
+ + + + +D GNY C V W W + + S P+ I
Sbjct: 497 ---TFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNI 541
>gi|169215606 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 195
Score = 240 bits (612), Expect = 7e-63
Identities = 115/117 (98%), Positives = 116/117 (99%)
Query: 16 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 75
VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM
Sbjct: 79 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 138
Query: 76 DSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGS 132
DSSFPYAIYTQRVRGGKIFIERVQGN TLLHITDLQARDAGEYECHTPST+KQYFGS
Sbjct: 139 DSSFPYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 195
Score = 38.1 bits (87), Expect = 0.050
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 681 QVSKSKRTLTLVENKPIQLNCSVKS-QTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAF 739
QV+ + L E I + C+V Q +F W ++ PS + ++ + +T +S+F
Sbjct: 85 QVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQ--WSIYLPSSPEREVQIVSTMDSSF 142
Query: 740 EYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCH 783
Y Y + +R F V G L + + D+G Y CH
Sbjct: 143 PYAIYTQR--VRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 184
Score = 37.4 bits (85), Expect = 0.086
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 802 VSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNH 861
VS + +VTV++ G L E + + C V + Q +W ++ P+
Sbjct: 80 VSAQRQVTVQE-----------GPLYRTEGSHITIWCNVSGYQGPSEQNF-QWSIYLPSS 127
Query: 862 PERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCH 919
PERE + D++F Y + G++ +E L I ++ +D+G Y CH
Sbjct: 128 PEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNPTLLHITDLQARDAGEYECH 184
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%)
Query: 471 PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 512
P + Y +R G + +E+VQ N L I + + D G+YECH
Sbjct: 143 PYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 184
>gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]
Length = 155
Score = 240 bits (612), Expect = 7e-63
Identities = 115/117 (98%), Positives = 116/117 (99%)
Query: 16 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 75
VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM
Sbjct: 39 VVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTM 98
Query: 76 DSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGS 132
DSSFPYAIYTQRVRGGKIFIERVQGN TLLHITDLQARDAGEYECHTPST+KQYFGS
Sbjct: 99 DSSFPYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 155
Score = 38.1 bits (87), Expect = 0.050
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 681 QVSKSKRTLTLVENKPIQLNCSVKS-QTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAF 739
QV+ + L E I + C+V Q +F W ++ PS + ++ + +T +S+F
Sbjct: 45 QVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQ--WSIYLPSSPEREVQIVSTMDSSF 102
Query: 740 EYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCH 783
Y Y + +R F V G L + + D+G Y CH
Sbjct: 103 PYAIYTQR--VRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 144
Score = 37.4 bits (85), Expect = 0.086
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 13/118 (11%)
Query: 802 VSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNH 861
VS + +VTV++ G L E + + C V + Q +W ++ P+
Sbjct: 40 VSAQRQVTVQE-----------GPLYRTEGSHITIWCNVSGYQGPSEQNF-QWSIYLPSS 87
Query: 862 PERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCH 919
PERE + D++F Y + G++ +E L I ++ +D+G Y CH
Sbjct: 88 PEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNPTLLHITDLQARDAGEYECH 144
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%)
Query: 471 PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 512
P + Y +R G + +E+VQ N L I + + D G+YECH
Sbjct: 103 PYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECH 144
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 67.0 bits (162), Expect = 1e-10
Identities = 185/971 (19%), Positives = 318/971 (32%), Gaps = 238/971 (24%)
Query: 80 PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNL 139
P AI T RGG + R Q + + L + + D+GEY C + S ++
Sbjct: 2657 PQAIITWYKRGGSL-PSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715
Query: 140 VVIPDSLQTTAMP-----QTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVE 194
S ++MP + H E + L+L C V + +H V W ++ G P
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQ----AHAQVTW-HKRGGSLP-- 2768
Query: 195 VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQD 254
+ Q+ G RL + H+ P+D GE+ C
Sbjct: 2769 ----------------SHHQTRGS-----------RLRLHHVSPADSGEYVCRVMG-SSG 2800
Query: 255 PDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYF 314
P + +T + S + V+V +R+E G+ ++ +C++ Q +
Sbjct: 2801 PLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ----AHA 2856
Query: 315 AVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKY 374
V+W + A + G L L++ + DSG+Y
Sbjct: 2857 QVTWHKRGGNLP--------------ARHQVHGPL-----------LRLNQVSPADSGEY 2891
Query: 375 NCRVTEREKTVTGEF---IDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFS 431
+C+VT T+ I+ S P P + P + + +++S + EG+ L +
Sbjct: 2892 SCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQP------IYIEASSSHVTEGQTLDLN 2945
Query: 432 CSVRTAGRPQGRFSVIW-----QLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQM 486
C V Q V W L R + + L G +S G +
Sbjct: 2946 CVVPGQAHAQ----VTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQ 3001
Query: 487 EQ-----VQPNSFSLGIFNS------------RKEDEGQYECHVTEWVRAVDGEWQIVGE 529
E V P+ S S ++ + ++C + + + EW+
Sbjct: 3002 EASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKT--- 3058
Query: 530 RRASTPISITALEMGFAVTAISRTPGV--TY----SDSFDL-QCIIK------------P 570
R ++ G +T + P TY S+++ + Q ++ P
Sbjct: 3059 RNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLP 3118
Query: 571 HYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRL 630
P WV V + V E +TR + RT ++ L
Sbjct: 3119 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTP-----AKLEQRTY---GLMDSHAVL 3170
Query: 631 SISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLT 690
IS A ++AG Y C+A+ N ++ +++ + P QV + LT
Sbjct: 3171 QISSAKPSDAGTYVCLAQ-------NALGTAQKQVEVIVDTGAMAPGAP-QVQAEEAELT 3222
Query: 691 LVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGL 750
+ L CS + H++ L
Sbjct: 3223 VEAGHTATLRCSATGSPAPTIHWSKL---------------------------------- 3248
Query: 751 RARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTV 810
R+ L ++ + G +L + R DSG Y C+ A +G E T+
Sbjct: 3249 RSPLPWQHRLEGD--TLIIPRVAQQDSGQYICN---------------ATSPAGHAEATI 3291
Query: 811 -KQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVAR 869
+S + + SV VQL+C+ +T F W
Sbjct: 3292 ILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLT-------FQW------------ 3332
Query: 870 LSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSG 929
SR + G A+N L LH E +P +DSG Y C V + S
Sbjct: 3333 -SRVGSSLPGRATARNEL---LHFERAAP------------EDSGRYRCRVTNKVGSAEA 3376
Query: 930 MWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVA 989
+ G T + ++ V T S A+ + C++ S D +
Sbjct: 3377 FAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPS----DRGTQLR 3432
Query: 990 WYSLRTKAGGK 1000
W+ K GG+
Sbjct: 3433 WF----KEGGQ 3439
Score = 66.2 bits (160), Expect = 2e-10
Identities = 177/829 (21%), Positives = 289/829 (34%), Gaps = 177/829 (21%)
Query: 81 YAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLV 140
+A T RGG + R Q + +LL + + D+GEY CH T S +
Sbjct: 2180 HAQVTWHKRGGSL-PARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEAS 2238
Query: 141 VIPDSLQTTAMPQTLHRV-EQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLS 199
VIP + + + V E L+L+C VA + +H V W ++ G P
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQ----AHAQVTWYKRG-GSLP------- 2286
Query: 200 RDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSW 259
A+ Q G RL IF P+D G++ C A+ ++ +
Sbjct: 2287 -----------ARHQVRGS-----------RLYIFQASPADAGQYVCRASNGME----AS 2320
Query: 260 YAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWA 319
+T ++GA + P +R+E G+ ++ C++ Q+ + V+W
Sbjct: 2321 ITVTVTGTQGANL-AYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQS----HAQVTW- 2374
Query: 320 FNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVT 379
H+ G L V ++ +L++Y DSG+Y CR
Sbjct: 2375 ----------------------HKRG-GSLPVRHQTHG-SLLRLYQASPADSGEYVCR-- 2408
Query: 380 EREKTVTGEFIDKESKRPKNI-PIIVLP-LKSSISVEVASNASVILEGEDLRFSCSVRTA 437
V G + E+ I P +P L + +V + S++S + EG+ L +C V
Sbjct: 2409 -----VLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQ 2463
Query: 438 GRPQ-------GRFSVIWQLVDRQNRRSNIMWLDRDGTV--QPGSSYWERSSFGGVQMEQ 488
Q G Q+ + R + D V GSS + +S V ++Q
Sbjct: 2464 AHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASV-LVTIQQ 2522
Query: 489 VQPNSFSLGI-FNSRKEDEG---------QYEC-------HVTEWVR---AVDGEWQIVG 528
S S G+ + R E C H W + ++ QIVG
Sbjct: 2523 RLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVG 2582
Query: 529 ERRASTPISITALEMGFAVTAISRTPGVTYSDSF-DLQCIIKPHYPAWVPVSVTWRFQPV 587
R +T + G V +S G + +Q H P+ P P
Sbjct: 2583 SRLRIP--QVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 2640
Query: 588 ----GTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKY 643
T++ + +V + W R S +R ++ L + + S ++G+Y
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEY 2694
Query: 644 QCVAELWRKNYNNTWTRLAERTSNLLEI-----RVLQPVTKLQVSKSKRTLTLVENKPIQ 698
C A NN L S ++ + P + + + + + E + +
Sbjct: 2695 VCRA-------NNNIDAL--EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 2745
Query: 699 LNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFER 758
LNC V Q +H V W H ++ + G R RL
Sbjct: 2746 LNCVVPGQ----AHAQVTW-----------------HKRGGSLPSHHQTRGSRLRL---H 2781
Query: 759 HVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLR 818
HVS +DSG Y C V P A + E SG + V V P
Sbjct: 2782 HVS------------PADSGEYVCRV-MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPP 2828
Query: 819 LSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETV 867
+ + V E + + L+CVV + + V W N P R V
Sbjct: 2829 IRIEPSSSRVAEGQTLDLKCVVPGQ----AHAQVTWHKRGGNLPARHQV 2873
Score = 48.9 bits (115), Expect = 3e-05
Identities = 101/515 (19%), Positives = 175/515 (33%), Gaps = 124/515 (24%)
Query: 77 SSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAK 136
S P+ I T RGG + R Q + L I + D+GEY CH + G+ S +
Sbjct: 2559 SQAPHTI-TWYKRGGSL-PSRHQIVGSRLRIPQVTPADSGEYVCHVSN------GAGSRE 2610
Query: 137 MNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVI 196
+L+V ++ +P P+ + E +S T+ L V +P +I
Sbjct: 2611 TSLIVTIQGSGSSHVPSV-----SPPIRI--ESSSPTVVEGQ--TLDLNCVVARQPQAII 2661
Query: 197 SLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPD 256
+ + S ++ Q+ G L + + +D GE+ C A I +
Sbjct: 2662 TWYK----RGGSLPSRHQTHGS-----------HLRLHQMSVADSGEYVCRANNNIDALE 2706
Query: 257 GSWYAMTRKRSEGAVVNVQPT-------DKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309
S V++V P+ +R+E+ GE ++ C++ Q
Sbjct: 2707 AS-----------IVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQ-- 2753
Query: 310 PDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQE 369
+ V+W + + H + RG L+++H+
Sbjct: 2754 --AHAQVTWHKRGGSLPS--------------HHQTRGSR-----------LRLHHVSPA 2786
Query: 370 DSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLR 429
DSG+Y CRV + + + + P + + + ++S + EG+ L
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAP-GGAPPIRIEPSSSRVAEGQTLD 2845
Query: 430 FSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGG--VQME 487
C V Q + W R G + R G +++
Sbjct: 2846 LKCVVPGQAHAQ------------------VTWHKRGGNLP------ARHQVHGPLLRLN 2881
Query: 488 QVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAV 547
QV P D G+Y C VT ++ + E + PI L +
Sbjct: 2882 QVSP------------ADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYI 2929
Query: 548 TAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTW 582
A S VT + DL C++ P VTW
Sbjct: 2930 EASS--SHVTEGQTLDLNCVV----PGQAHAQVTW 2958
Score = 44.7 bits (104), Expect = 5e-04
Identities = 195/999 (19%), Positives = 320/999 (32%), Gaps = 291/999 (29%)
Query: 80 PYAIYTQRVRGGKIFIERVQGNSTL--LHITDLQARDAGEYECHTPSTDKQYFGSYSAKM 137
P A T R GG + + + + L I + DAG Y C S G+ A++
Sbjct: 1983 PSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPA----GTAQARI 2038
Query: 138 NLVVI--------PDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVG 189
+VV+ P +++++ T E L+L C VA +H V W R+
Sbjct: 2039 QVVVLSASDASPPPVKIESSSPSVT----EGQTLDLNCVVAGS----AHAQVTWYRRGG- 2089
Query: 190 EKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAA 249
SL +H S RL + + P+D GE+ C
Sbjct: 2090 -------SLPPHTQVHGS----------------------RLRLPQVSPADSGEYVCRVE 2120
Query: 250 EWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309
+ S + +R+E G+ ++ C++ Q
Sbjct: 2121 NGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQ-- 2178
Query: 310 PDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQE 369
+ V+W RG A+ +L+++ +
Sbjct: 2179 --AHAQVTW-------------------------HKRGGSLPARHQTHGSLLRLHQVTPA 2211
Query: 370 DSGKYNCRVTEREKTVTGEFID--KESKRPKNIPIIVLPLKSSISVEVASNASVILEGED 427
DSG+Y C V + + + S P IP V + S++S + EG+
Sbjct: 2212 DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIP----------PVRIESSSSTVAEGQT 2261
Query: 428 LRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQME 487
L SC V AG+ + + W R GG
Sbjct: 2262 LDLSCVV--AGQ----------------AHAQVTWYKR----------------GGSLPA 2287
Query: 488 QVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALE-MGFA 546
+ Q L IF + D GQY C RA +G AS +++T + A
Sbjct: 2288 RHQVRGSRLYIFQASPADAGQYVC------RASNG-------MEASITVTVTGTQGANLA 2334
Query: 547 VTAISRTP--------GVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTF 598
A S P V + DL C++ P VTW
Sbjct: 2335 YPAGSTQPIRIEPSSSQVAEGQTLDLNCVV----PGQSHAQVTWH--------------- 2375
Query: 599 TRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTW 658
+ GG ++ ++ L + +AS ++G+Y C
Sbjct: 2376 -KRGG--------------SLPVRHQTHGSLLRLYQASPADSGEYVC---------RVLG 2411
Query: 659 TRLAERTSNLLEIRVLQPVTKLQVSKSKR----TLTLVENKPIQLNCSVKSQTSQNSHFA 714
+ + S L+ I V L V+ + R + + E + + LNC V Q +H
Sbjct: 2412 SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQ----AHAQ 2467
Query: 715 VLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEV 774
V W+ S L H + G R RL +
Sbjct: 2468 VTWHKRGGS-------LPARH----------QVHGSRLRL---------------LQVTP 2495
Query: 775 SDSGSYYCHVEEWLLSPNYA-WYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQ 833
+DSG Y C V + + + + +SG V P +R+ + +L+ T
Sbjct: 2496 ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYP---VRIESSSASLANGHT-- 2550
Query: 834 VQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHL 893
+ L C+V ++ T + W+ + P R +
Sbjct: 2551 LDLNCLVASQAPHT----ITWYKRGGSLPSRHQIVG------------------------ 2582
Query: 894 ESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASL 953
RL I V DSG Y CHV S + + +V P +
Sbjct: 2583 -------SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP---I 2632
Query: 954 QVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWY----SLRTKAGGKRSSPGLEEQ 1009
++++ P TV E L+C +V+R Q + WY SL ++ S L +
Sbjct: 2633 RIESSSP--TVVEGQTLDLNC-VVARQPQ---AIITWYKRGGSLPSRHQTHGSHLRLHQM 2686
Query: 1010 EEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSP 1048
E +++ D E + ++SV P A GSP
Sbjct: 2687 SVADSGEYVCRANNNIDALEASIVISVSPSA-----GSP 2720
Score = 40.4 bits (93), Expect = 0.010
Identities = 130/700 (18%), Positives = 235/700 (33%), Gaps = 176/700 (25%)
Query: 75 MDSSFPYAIYTQRVRGGKI---FIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFG 131
+ S P+ Y R G + +R QG+ LH +Q DAG Y C T +
Sbjct: 1700 VSGSPPHYFYWSREDGRPVPSGTQQRHQGSE--LHFPSVQPSDAGVYIC----TCRNLHQ 1753
Query: 132 SYSAKMNLVV--IPDSLQTTAMPQTLHRVEQDPLELT--CEVASETIQHSHLSVAWLRQK 187
S +++ L+V P T + + + + ++T C S++ + ++ W R
Sbjct: 1754 SNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAY---TLVWTRLH 1810
Query: 188 VGEKPVEV-------------ISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIF 234
G+ P +S + ++ S+ +A Q + + G + +
Sbjct: 1811 NGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSI 1870
Query: 235 H-----LQPSDQGEFYCEAA-------EWIQDPDGSWYAMTRKRSEGAVVN---VQPTDK 279
H +QP EF C A EW P G A + + G ++ V+PTD
Sbjct: 1871 HPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPA--KAQIHGGILRLPAVEPTD- 1927
Query: 280 EFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVS---WAFNSSLIATMGPNAVPVL 336
+ + R H+ R +L VS ++ + A V
Sbjct: 1928 ----QAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVP 1983
Query: 337 NSEFAHREARGQL--KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394
++ R+ G L + E + L I + D+G Y C T T
Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQA------- 2036
Query: 395 KRPKNIPIIVLPLK--SSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVD 452
I ++VL S V++ S++ + EG+ L +C V + Q
Sbjct: 2037 ----RIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQ----------- 2081
Query: 453 RQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 512
+ W R G++ P + + +++ QV P D G+Y C
Sbjct: 2082 -------VTWYRRGGSLPPHT----QVHGSRLRLPQVSP------------ADSGEYVCR 2118
Query: 513 VTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPG-------------VTYS 559
V G I+++ L + + + PG V
Sbjct: 2119 VEN------------GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEG 2166
Query: 560 DSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAI 619
+ DL C++ P VTW + GG ++
Sbjct: 2167 QTLDLNCVV----PGQAHAQVTWH----------------KRGG--------------SL 2192
Query: 620 EKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQ-PVT 678
++ L + + + ++G+Y C + T L +E V+ P+
Sbjct: 2193 PARHQTHGSLLRLHQVTPADSGEYVC-------HVVGTSGPLEASVLVTIEASVIPGPIP 2245
Query: 679 KLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWY 718
+++ S + T+ E + + L+C V Q +H V WY
Sbjct: 2246 PVRIESS--SSTVAEGQTLDLSCVVAGQ----AHAQVTWY 2279
Score = 40.0 bits (92), Expect = 0.013
Identities = 133/621 (21%), Positives = 199/621 (32%), Gaps = 182/621 (29%)
Query: 27 EGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQ 86
EGP++ G +T+ C +G P S R +I ST A Q
Sbjct: 3119 EGPVWVKVGKAVTLECVSAGE--------------PRSSARWTRISSTP------AKLEQ 3158
Query: 87 RVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSL 146
R G + + +L I+ + DAG Y C + G+ ++ ++V
Sbjct: 3159 RTYG-------LMDSHAVLQISSAKPSDAGTYVCLAQNA----LGTAQKQVEVIV----- 3202
Query: 147 QTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHS 206
T AM +V+ + ELT E A LR P I S+ L S
Sbjct: 3203 DTGAMAPGAPQVQAEEAELTVEAGH---------TATLRCSATGSPAPTIHWSK---LRS 3250
Query: 207 SSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKR 266
+ R G T L I + D G++ C A P G A
Sbjct: 3251 PLPWQHRLE---------GDT---LIIPRVAQQDSGQYICNATS----PAGHAEATI--- 3291
Query: 267 SEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIA 326
+++V+ TV E GE V+ +C+ A P F W S +
Sbjct: 3292 ----ILHVESPPYATTV---PEHASVQAGETVQLQCL--AHGTPPLTF--QW----SRVG 3336
Query: 327 TMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVT 386
+ P N E H E EDSG+Y CRVT + +
Sbjct: 3337 SSLPGRATARN-ELLHFERAAP--------------------EDSGRYRCRVTNKVGSAE 3375
Query: 387 GEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSV 446
P ++P +P S+ +V+V G + F C+V +
Sbjct: 3376 AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPS---------- 3425
Query: 447 IWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDE 506
+R + + W G + PG S + GV L I N + +
Sbjct: 3426 --------DRGTQLRWFKEGGQLPPGHSVQD-----GV-----------LRIQNLDQSCQ 3461
Query: 507 GQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQC 566
G Y C G W G+ +AS + I AL P V + +Q
Sbjct: 3462 GTYICQ-------AHGPW---GKAQASAQLVIQAL------------PSVLINIRTSVQT 3499
Query: 567 IIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSN 626
++ H VEF L V W R +S
Sbjct: 3500 VVVGH-----------------AVEFECLALGDPKPQVTWSKVGGHLRPGI----VQSGG 3538
Query: 627 NVRLSISRASDTEAGKYQCVA 647
VR++ +D AG+Y+C A
Sbjct: 3539 VVRIAHVELAD--AGQYRCTA 3557
>gi|31377806 polymeric immunoglobulin receptor precursor [Homo
sapiens]
Length = 764
Score = 50.1 bits (118), Expect = 1e-05
Identities = 120/552 (21%), Positives = 206/552 (37%), Gaps = 100/552 (18%)
Query: 7 VLSCL-AVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65
VL+CL AV +S + + E + EG+ ++I C Y P+ N Y
Sbjct: 5 VLTCLLAVFPAISTKSPIFGPE-EVNSVEGNSVSITC----YYPPTSVNRHTRKYWCRQG 59
Query: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNST-LLHITDLQARDAGEYECHTPS 124
R I + + Y G+ + N T +++I L D+G Y+C
Sbjct: 60 ARGGCITLISSEGYVSSKYA-----GRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGI 114
Query: 125 TDKQYFGSYSAKMNLVVIPDSLQTTAMPQT-LHRVEQDPLELTCEVASETIQHSHLSVAW 183
+ S+ + + P L T + L R + + C +E Q
Sbjct: 115 NSRGL--SFDVSLEVSQGPGLLNDTKVYTVDLGRT----VTINCPFKTENAQKRKS---- 164
Query: 184 LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLD--KLGRTTFRLTIFHLQPSDQ 241
L +++G PV VI SS Y G +RLD G+ F + I L+ SD
Sbjct: 165 LYKQIGLYPVLVID---------SSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDA 215
Query: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301
G++ C+A + D + + +K ++ V+ +P E + V F
Sbjct: 216 GQYLCQAGD---DSNSN-----KKNADLQVLKPEP-----------ELVYEDLRGSVTFH 256
Query: 302 CIL--EAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVF 359
C L E NV S N ++ P L ++ D F
Sbjct: 257 CALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRI--------LLNPQDKDGSF 308
Query: 360 VLKIYHLRQEDSGKYNCRVTEREKTVTGE-------FIDKESKRPKNIPIIVLPLKSSIS 412
+ I LR+ED+G+Y C + G F+++ES P++ ++ S++
Sbjct: 309 SVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVA 368
Query: 413 VEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPG 472
V N E + +++ C +W+ QN R ++ +D +G V+
Sbjct: 369 VLCPYNRK---ESKSIKYWC--------------LWE--GAQNGRCPLL-VDSEGWVK-- 406
Query: 473 SSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV---TEWVRAVDGEWQIVGE 529
+ Y R S +E+ +F++ + D G Y C T W V+ + I GE
Sbjct: 407 AQYEGRLSL----LEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIK-IIEGE 461
Query: 530 RRASTPISITAL 541
P ++TA+
Sbjct: 462 PNLKVPGNVTAV 473
>gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens]
Length = 191
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/95 (28%), Positives = 42/95 (44%)
Query: 692 VENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 751
+E + L C V + ++S AV W+ D+ L++K T +Y R
Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96
Query: 752 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEE 786
RL+ G L+ L+V + SD G Y C V+E
Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 35.0 bits (79), Expect = 0.43
Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 829 LETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 888
LE L C V + S L V WF + + ++++ Y +++ +
Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96
Query: 889 GRLHL-ESPSPGVYRLFIQNVAVQDSGTYSCHVEE 922
RL L E +YRL + + D G Y C V+E
Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 34.7 bits (78), Expect = 0.56
Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Query: 145 SLQTTAMP-QTLHRVEQDPLELTCEVASETIQHSHLSVAWL-RQKVGEKPVEVISLSRDF 202
+L T P + +E + L C V+ + + S L+V W + ++ +++
Sbjct: 23 ALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLR 82
Query: 203 MLHSSSEYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCEAAE 250
++ +++ +RL + R +RL++ LQPSDQG + C E
Sbjct: 83 VVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 32.3 bits (72), Expect = 2.8
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 7/93 (7%)
Query: 295 GEPVEFRCILEAQNVPDRYFAVSWAFNSS------LIATMGPNAVPVLNSEFAHREARGQ 348
GE C + + D AV W F S L+ M V F+ R +
Sbjct: 39 GENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRR 98
Query: 349 LKVAKES-DSVFVLKIYHLRQEDSGKYNCRVTE 380
L++ +E +++ L + L+ D G Y CRV E
Sbjct: 99 LRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 32.3 bits (72), Expect = 2.8
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 1062 LYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESA 1102
LYRL+VL P D G+Y C V+E + + +W + SA
Sbjct: 109 LYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTAWSNGSSA 148
>gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo
sapiens]
Length = 320
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/95 (28%), Positives = 42/95 (44%)
Query: 692 VENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 751
+E + L C V + ++S AV W+ D+ L++K T +Y R
Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96
Query: 752 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEE 786
RL+ G L+ L+V + SD G Y C V+E
Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 35.0 bits (79), Expect = 0.43
Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 6/140 (4%)
Query: 145 SLQTTAMP-QTLHRVEQDPLELTCEVASETIQHSHLSVAWL-RQKVGEKPVEVISLSRDF 202
+L T P + +E + L C V+ + + S L+V W + ++ +++
Sbjct: 23 ALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLR 82
Query: 203 MLHSSSEYAQRQSLGEVRLDKLGR-TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYA 261
++ +++ +RL + R +RL++ LQPSDQG + C E I W A
Sbjct: 83 VVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTA 141
Query: 262 MTRKRS--EGAVVNVQPTDK 279
+ S E V++++ +++
Sbjct: 142 WSNGSSATEMRVISLKASEE 161
Score = 35.0 bits (79), Expect = 0.43
Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 829 LETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 888
LE L C V + S L V WF + + ++++ Y +++ +
Sbjct: 37 LEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKR 96
Query: 889 GRLHL-ESPSPGVYRLFIQNVAVQDSGTYSCHVEE 922
RL L E +YRL + + D G Y C V+E
Sbjct: 97 RRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 33.9 bits (76), Expect = 0.95
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 1062 LYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSIICS 1121
LYRL+VL P D G+Y C V+E + + +W + SA +RV+ + +S
Sbjct: 109 LYRLSVLTLQPSDQGHYVCRVQE-ISRHRNKWTAWSNGSSA-TEMRVISLKASEESSFEK 166
Query: 1122 ND---ALFYFVFFYPFPIFGILIITILL 1146
A F ++ Y + + I++ILL
Sbjct: 167 TKETWAFFEDLYVYAVLVCCVGILSILL 194
Score = 32.3 bits (72), Expect = 2.8
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 7/93 (7%)
Query: 295 GEPVEFRCILEAQNVPDRYFAVSWAFNSS------LIATMGPNAVPVLNSEFAHREARGQ 348
GE C + + D AV W F S L+ M V F+ R +
Sbjct: 39 GENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRR 98
Query: 349 LKVAKES-DSVFVLKIYHLRQEDSGKYNCRVTE 380
L++ +E +++ L + L+ D G Y CRV E
Sbjct: 99 LRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
>gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]
Length = 585
Score = 45.4 bits (106), Expect = 3e-04
Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 952 SLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEE 1011
S +++T A + ++A +LDC ++ ++ S T + + +P ++EE
Sbjct: 316 SFEIETEPQAAVLHLQSAEELDCQ--GEEEEEEEDGSSFCSGVTDSSTQSLAPSESDEEE 373
Query: 1012 EREEEEEEDDDDDDD 1026
E EEEEEE++DDDDD
Sbjct: 374 EEEEEEEEEEDDDDD 388
>gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo
sapiens]
Length = 120
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 1 MKCFFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIY 60
M C + +L +A AQ Q+ VQ G + G+ + + C VSGY +E + W
Sbjct: 1 MDCTWRILFLVAAATGTHAQVQL-VQSGAEVKKPGASVKVSCKVSGYT-LTELSMHW--- 55
Query: 61 LPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYEC 120
+ +P + ++ + D IY Q+ +G E ++ + ++ L++ D Y C
Sbjct: 56 VRQAPGKGLEWMGGFDPEDGETIYAQKFQGRVTMTEDTSTDTAYMELSSLRSEDTAVYYC 115
Query: 121 HT 122
T
Sbjct: 116 AT 117
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 43.1 bits (100), Expect = 0.002
Identities = 104/507 (20%), Positives = 186/507 (36%), Gaps = 104/507 (20%)
Query: 230 RLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEK 289
RLTI++ D G + C+A + + +++ A V ++ K T R
Sbjct: 77 RLTIYNANIEDAGIYRCQATD------------AKGQTQEATVVLEIYQK-LTFREVVSP 123
Query: 290 RLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 349
+ GE E C + + P AVSW +++ + T+ N +L +
Sbjct: 124 QEFKQGEDAEVVCRVSSSPAP----AVSWLYHNEEVTTISDNRFAMLANNN--------- 170
Query: 350 KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKS 409
L+I ++ + D G Y C E GE ++ I+++ +
Sbjct: 171 -----------LQILNINKSDEGIYRC---EGRVEARGEIDFRDI-------IVIVNVPP 209
Query: 410 SISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIW----QLVDRQN----RRSNIM 461
+IS+ S + GE++ FSC R +G P+ S W +L++ + SN
Sbjct: 210 AISMPQKSFNATAERGEEMTFSC--RASGSPEPAIS--WFRNGKLIEENEKYILKGSNTE 265
Query: 462 WLDRDGTVQPGSSYWERSSFGGVQMEQ-------VQPNSFSL--------GIFNSRKEDE 506
R+ G Y R++ + E+ VQP+ L G + E
Sbjct: 266 LTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAE 325
Query: 507 GQYECHVTEWVRAVDGEWQIVGER-----------RASTPISITALEMG----FAVTAIS 551
G+ +T W RAVDG G++ S+ + I +++ + A S
Sbjct: 326 GEPIPEIT-WKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAAS 384
Query: 552 RTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSS 611
R G S D++ P + + + +W P + V + W
Sbjct: 385 RIGGHQKSMYLDIE--YAPKFISNQTIYYSWEGNP---INISCDVKSNPPASIHWRRDKL 439
Query: 612 SF--RTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLL 669
+ T ++ + + L I+ SD + G+Y C A N+ TR E L
Sbjct: 440 VLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTAT------NHIGTRFQEYILALA 493
Query: 670 EIRVLQPVTKLQVSKSKRTLTLVENKP 696
++ K+ + S+ T + NKP
Sbjct: 494 DVPSSPYGVKI-IELSQTTAKVSFNKP 519
Score = 35.0 bits (79), Expect = 0.43
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 91 GKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTA 150
G+I ++ G+S+L HI D++ D+G Y+C S G + M L + +
Sbjct: 352 GRIEVKGQHGSSSL-HIKDVKLSDSGRYDCEAASR----IGGHQKSMYLDI--EYAPKFI 404
Query: 151 MPQTL-HRVEQDPLELTCEVASETIQHSHLSVAWLRQKV 188
QT+ + E +P+ ++C+V S + S+ W R K+
Sbjct: 405 SNQTIYYSWEGNPINISCDVKS----NPPASIHWRRDKL 439
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.7 bits (99), Expect = 0.002
Identities = 106/519 (20%), Positives = 180/519 (34%), Gaps = 112/519 (21%)
Query: 496 LGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPG 555
L I +S ED GQY C++ + S I LE + V +
Sbjct: 7925 LEIPSSTVEDAGQYNCYIEN------------ASGKDSCSAQILILEPPYFVKQLEPVK- 7971
Query: 556 VTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRT 615
V+ DS LQC Q GT E GV W + R
Sbjct: 7972 VSVGDSASLQC------------------QLAGTPEI----------GVSWYKGDTKLRP 8003
Query: 616 RTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQ 675
T + +N L ++ ++G+Y C AE N+ ++ T ++ + L
Sbjct: 8004 TTTYKMHFRNNVATLVFNQVDINDSGEYICKAE-------NSVGEVSASTFLTVQEQKLP 8056
Query: 676 PVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVH-KPSDADGKL----- 729
P Q+ + T+ L P+ +C++ S + +V WY KP +
Sbjct: 8057 PSFSRQLRDVQETVGL----PVVFDCAI----SGSEPISVSWYKDGKPLKDSPNVQTSFL 8108
Query: 730 -------ILKTTHNSAFEYGTYAE----EEGLRARLQFERHVSGGLFSLTVQ--RAEVSD 776
I KT + A +Y A ARL + F + + A V +
Sbjct: 8109 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGE 8168
Query: 777 SGSYYCHVEEWLLSPNYAWYKLAEEV--SGRTEVTVKQPDSRLRLSQAQGNLSVLETRQV 834
S + CHV +W K + E+ G+ +++ + + L + L V +
Sbjct: 8169 SADFECHV-TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV------LKVDKGDSG 8221
Query: 835 QLECVVLN---RTSITSQLMVEWFVWKPNHPER--ETVARLSRDATFHYGEQAAKNNL-- 887
Q C +N + S T+QL ++ + P+ +R ETV ++ G A +
Sbjct: 8222 QYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 8281
Query: 888 ---KGRLHLESPS-------PGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAED 937
K + ++ S L ++ + D+G Y+C V A
Sbjct: 8282 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVS-----------NDAGS 8330
Query: 938 TAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI 976
+++ + P D + TVSE QL C +
Sbjct: 8331 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHV 8369
Score = 40.8 bits (94), Expect = 0.008
Identities = 127/656 (19%), Positives = 216/656 (32%), Gaps = 174/656 (26%)
Query: 102 STLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQD 161
S +L I DAG+Y C+ + + S SA++ L++ P P + D
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGK--DSCSAQI-LILEPPYFVKQLEPVKVS--VGD 7976
Query: 162 PLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRL 221
L C++A + V+W + +P + +H + A
Sbjct: 7977 SASLQCQLAGTP----EIGVSWYKGDTKLRPTTT------YKMHFRNNVAT--------- 8017
Query: 222 DKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEF 281
L + +D GE+ C+A + + S + V Q F
Sbjct: 8018 ---------LVFNQVDINDSGEYICKAENSVGEVSASTFL---------TVQEQKLPPSF 8059
Query: 282 TVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFA 341
+ +L + TVG PV F C + +VSW + + P + + F
Sbjct: 8060 SRQLRDVQE--TVGLPVVFDCAISGSEP----ISVSWYKDGKPLKDS-----PNVQTSFL 8108
Query: 342 HREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTER--EKTVTGEFIDKESKRPKN 399
D+ L I+ + +G+Y+C T + + I E K P
Sbjct: 8109 --------------DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPF 8154
Query: 400 IPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSN 459
I + P+ + + GE F C V T +P
Sbjct: 8155 FDIRLAPVDAVV-------------GESADFECHV-TGTQP-----------------IK 8183
Query: 460 IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRA 519
+ W ++ G Y Q+ ++ NS L + K D GQY C+ V
Sbjct: 8184 VSWAKDSREIRSGGKY---------QISYLE-NSAHLTVLKVDKGDSGQYTCYAVNEVGK 8233
Query: 520 VDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVS 579
Q+ + R P S T +S T T +SF L+ + P++
Sbjct: 8234 DSCTAQLNIKERLIPP-SFT--------KRLSETVEETEGNSFKLEGRVAGSQ----PIT 8280
Query: 580 VTW-----RFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISR 634
V W QP E +TF +N + L + +
Sbjct: 8281 VAWYKNNIEIQPTSNCE----ITF-------------------------KNNTLVLQVRK 8311
Query: 635 ASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVEN 694
A +AG Y C K N+ + L TS+++ + +P + +T+ E
Sbjct: 8312 AGMNDAGLYTC------KVSNDAGSALC--TSSIV---IKEPKKPPVFDQHLTPVTVSEG 8360
Query: 695 KPIQLNCSVKSQTSQNSHFAVLWYVHKPSD------ADGKLILKTTHNSAFEYGTY 744
+ +QL+C V+ + KPSD A G +L+ + + G Y
Sbjct: 8361 EYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDY 8416
Score = 38.1 bits (87), Expect = 0.050
Identities = 65/307 (21%), Positives = 117/307 (38%), Gaps = 78/307 (25%)
Query: 8 LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSS--- 64
+S A +V +R V+++ L + ++ T C VS G + ++ P S
Sbjct: 5277 ISTSAKYRLVCHERSVSLEVNNLELEDTANYT--CKVSNVAGDDACSGILTVKEPPSFLV 5334
Query: 65 --------PEREVQIVSTMDSSFPYAIY-----TQRVRGGKIFIERVQGNSTLLHITDLQ 111
P+ V+ + + + P+ I + V G K FI ++G+++ L++ +
Sbjct: 5335 KPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIG-LEGSTSFLNLYSVD 5393
Query: 112 ARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQ-------DPLE 164
A G+Y CH + GS S L+V T P+ + ++E D
Sbjct: 5394 ASKTGQYTCHVTND----VGSDSCTTMLLV-------TEPPKFVKKLEASKIVKAGDSSR 5442
Query: 165 LTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR--QSLGEVRLD 222
L C++A G + V+ + L +S +Y S+ ++++
Sbjct: 5443 LECKIA------------------GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 5484
Query: 223 KLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFT 282
+L D G+F CEA Q+P GS T+ +V P F
Sbjct: 5485 ------------NLSTEDSGDFICEA----QNPAGSTSCSTK-----VIVKEPPVFSSFP 5523
Query: 283 VRLETEK 289
+ET K
Sbjct: 5524 PIVETLK 5530
Score = 37.4 bits (85), Expect = 0.086
Identities = 143/671 (21%), Positives = 238/671 (35%), Gaps = 120/671 (17%)
Query: 356 DSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEV 415
DSV VL++++L EDSG Y C G S + K PI K +E
Sbjct: 7358 DSVAVLEMHNLSVEDSGDYTCEA----HNAAGSASSSTSLKVKEPPIF---RKKPHPIET 7410
Query: 416 ASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSY 475
L+G D+ C ++ G P F V W D++ RS G Y
Sbjct: 7411 -------LKGADVHLECELQ--GTPP--FHVSW-YKDKRELRS-------------GKKY 7445
Query: 476 WERSSFGGVQMEQVQPNSF--SLGIFNSRKEDEGQYECHVTEWVRA--VDGEWQIVGERR 531
++ +F S+ I N D G+Y+C T V + G + R
Sbjct: 7446 ------------KIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPR 7493
Query: 532 ASTPISITALEMGFAV---TAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVG 588
+S + +G V T I ++ D I++ W+ S
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFS 7553
Query: 589 TVEFHDLVTFT----RDGGVQWGDRS-SSFRTRTAIEKAESSNNVRLSISRASDTEAGKY 643
VE + +T D G+Q + S T +EK ES T AG
Sbjct: 7554 RVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTP 7613
Query: 644 QCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQV-----SKSKRTLTLVENKPIQ 698
+ + ++ T + N +I V+ L++ S S V+N +
Sbjct: 7614 ELSTKWFKDGKELT-------SDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGK 7666
Query: 699 LNCSVKSQTSQN----SHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARL 754
+C+ Q S S L + S + + K + + E + +
Sbjct: 7667 DSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGR 7726
Query: 755 QFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPD 814
+++ ++ +LTV E SDSG Y C ++ N A ++E S +TV++P
Sbjct: 7727 KYQTTLTDNTCALTVNMLEESDSGDYTC------IATNMAG---SDECS--APLTVREPP 7775
Query: 815 SRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVW--------KPNHPERET 866
S Q + VL V +V T V WF + N ++
Sbjct: 7776 S---FVQKPDPMDVLTGTNVTFTSIVKG----TPPFSVSWFKGSSELVPGDRCNVSLEDS 7828
Query: 867 VARL---------SRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQD----S 913
VA L S + T +A K + L++++P+ V RL ++
Sbjct: 7829 VAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILE 7888
Query: 914 GTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLD 973
GT++ P S W K + + + S ++ +P++TV + A Q +
Sbjct: 7889 GTFT-----GTPPISVTWKKNGINVTPSQRCNITTTEKSAILE--IPSSTVED--AGQYN 7939
Query: 974 CSIVSRSSQDS 984
C I + S +DS
Sbjct: 7940 CYIENASGKDS 7950
Score = 37.0 bits (84), Expect = 0.11
Identities = 69/317 (21%), Positives = 111/317 (35%), Gaps = 88/317 (27%)
Query: 471 PGSSYWERSSFGGVQMEQVQ----PNSFSLGIFNSRKEDEGQYECHV-TEWVRAVDGEWQ 525
P S W++ F E+ + L I NS K D GQY C + E R V G
Sbjct: 6014 PISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCG--- 6070
Query: 526 IVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQ 585
++ LE + VT + DS LQC Q
Sbjct: 6071 ----------ALVSTLEPPYFVTELEPLEAAV-GDSVSLQC------------------Q 6101
Query: 586 PVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQC 645
GT E V W + R ++N L ++ + ++G+Y C
Sbjct: 6102 VAGTPEI----------TVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 6151
Query: 646 VAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKS 705
AE N+ + +T ++ R L P Q+ ++T+ L P+ L C +
Sbjct: 6152 KAE-------NSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGL----PVTLTCRLNG 6200
Query: 706 QTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLF 765
++ V WY DG L+ ++E L+ F +V+
Sbjct: 6201 ----SAPIQVCWY------RDGVLL--------------RDDENLQT--SFVDNVA---- 6230
Query: 766 SLTVQRAEVSDSGSYYC 782
+L + + ++S SG Y C
Sbjct: 6231 TLKILQTDLSHSGQYSC 6247
Score = 36.6 bits (83), Expect = 0.15
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 100 GNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVE 159
G LHI D+Q DAGEY C +K+ + +AK+ + +P T + + + V+
Sbjct: 11170 GKDRKLHIIDVQLSDAGEYTCVLRLGNKE--KTSTAKLVVEELPVRFVKT-LEEEVTVVK 11226
Query: 160 QDPLELTCEVASETIQHSHLSVAWLR--QKVGEKPVEVI 196
PL L+CE+ E V W + + V EKP ++
Sbjct: 11227 GQPLYLSCELNKER------DVVWRKDGKIVVEKPGRIV 11259
Score = 35.8 bits (81), Expect = 0.25
Identities = 56/260 (21%), Positives = 95/260 (36%), Gaps = 28/260 (10%)
Query: 738 AFEYGTYAEEEGLRARLQFERHVSG-GLFSLTVQRAEVSDSGSYYCHV-------EEWLL 789
A E Y + + L+ F+ H S G + L + SD G Y C + + L
Sbjct: 32746 AKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQ 32805
Query: 790 SPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSI 846
A+ + E+VS +E K+ D + S + + V+ L T++
Sbjct: 32806 FMGQAFKSIHEKVSKISE--TKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTV 32863
Query: 847 TSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQ 906
+S + ++ V P + + K +G + S G + L I
Sbjct: 32864 SSDSVAKFAVKATGEPRPTAI-----------WTKDGKAITQGGKYKLSEDKGGFFLEIH 32912
Query: 907 NVAVQDSGTYSCHVEEWLPSPSG---MWYKRAEDTAGQTALTVMRPDASLQVDTVVPNAT 963
DSG Y+C V+ S S + K +DT Q T + + Q VV
Sbjct: 32913 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVV-QEE 32971
Query: 964 VSEKAAFQLDCSIVSRSSQD 983
+S+KA + + SQ+
Sbjct: 32972 ISQKALRSEEIKMSEAKSQE 32991
Score = 35.4 bits (80), Expect = 0.33
Identities = 93/503 (18%), Positives = 190/503 (37%), Gaps = 51/503 (10%)
Query: 228 TFRLTIFHLQPSDQGEFYCE-------AAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKE 280
T+ L I +L SDQGE+ CE + +Q ++ ++ K S+ + + +D++
Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK--ISETKKSDQK 32830
Query: 281 FTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEF 340
T T K EP+ + ++ + D + ++ AT P + +
Sbjct: 32831 TTESTVTRKTEPKAPEPISSKPVI-VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG 32889
Query: 341 AHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGE-------FIDKE 393
G+ K++++ F L+I+ DSG Y C V +V+ D E
Sbjct: 32890 KAITQGGKYKLSEDKGG-FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTE 32948
Query: 394 SKR--PKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLV 451
+++ + I K+ + E++ A L E+++ S ++ + + L+
Sbjct: 32949 AQKVSTQKTSEITPQKKAVVQEEISQKA---LRSEEIKMS-EAKSQEKLALKEEASKVLI 33004
Query: 452 DRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYEC 511
+ ++S L++ S E + E+V+ ++ +EGQ
Sbjct: 33005 SEEVKKSAATSLEK-------SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLV 33057
Query: 512 HVTEWVRAVDGEWQIVGERRASTP---ISITALEMGFAVTAIS-RTPGVTYSDSFDLQCI 567
A D +W + G ++ ++ + + S R G+ S + I
Sbjct: 33058 LKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGI 33117
Query: 568 IKPHY-----------PAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTR 616
+K Y PA++ + V F ++ ++W +
Sbjct: 33118 VKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISIS 33177
Query: 617 TAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWT----RLAERTSNLLEIR 672
+ + + S N L I AS +++GKY A+ +R + T + L E S + +R
Sbjct: 33178 SNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 33237
Query: 673 VLQPVTKLQVSKSKRTLTLVENK 695
T LQ S S +++ + +K
Sbjct: 33238 T-SGDTSLQGSFSSQSVQMSASK 33259
Score = 33.9 bits (76), Expect = 0.95
Identities = 32/132 (24%), Positives = 63/132 (47%), Gaps = 11/132 (8%)
Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVR-GGKIFIERVQGNSTLLHITDLQARDAGEYECHT 122
S + E + T +A ++ +R GGK I ++ NS L + + D+G+Y C+
Sbjct: 8169 SADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLE-NSAHLTVLKVDKGDSGQYTCY- 8226
Query: 123 PSTDKQYFGSYSAKMNLV--VIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLS 180
+ ++ S +A++N+ +IP S T + +T+ E + +L VA ++
Sbjct: 8227 -AVNEVGKDSCTAQLNIKERLIPPSF-TKRLSETVEETEGNSFKLEGRVAGS----QPIT 8280
Query: 181 VAWLRQKVGEKP 192
VAW + + +P
Sbjct: 8281 VAWYKNNIEIQP 8292
Score = 32.3 bits (72), Expect = 2.8
Identities = 87/417 (20%), Positives = 133/417 (31%), Gaps = 118/417 (28%)
Query: 104 LLHITDLQARDAGEYECHTPS-TDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDP 162
+L I + RDAG+Y C + + G+ + + P T P L D
Sbjct: 6042 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE----PPYFVTELEP--LEAAVGDS 6095
Query: 163 LELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLD 222
+ L C+VA ++V+W + D L + EY
Sbjct: 6096 VSLQCQVAGTP----EITVSWYKG--------------DTKLRPTPEY------------ 6125
Query: 223 KLGRTTFR-----LTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPT 277
RT F L + +D GE+ C+A I S V +Q
Sbjct: 6126 ---RTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTA-----------SSKTVFRIQER 6171
Query: 278 DKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLN 337
+ + + TVG PV C L + P V W + ++ N L
Sbjct: 6172 QLPPSFARQLKDIEQTVGLPVTLTCRLNG-SAP---IQVCW-YRDGVLLRDDEN----LQ 6222
Query: 338 SEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRP 397
+ F D+V LKI SG+Y+C + T + ++ P
Sbjct: 6223 TSFV--------------DNVATLKILQTDLSHSGQYSCSASNPLGTASSS-ARLTAREP 6267
Query: 398 KNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRR 457
K P + +S++V + GE F C V T +P
Sbjct: 6268 KKSPFFDI---KPVSIDV-------IAGESADFECHV-TGAQPM---------------- 6300
Query: 458 SNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 514
I W + ++PG +Y N+ L I K D GQY C T
Sbjct: 6301 -RITWSKDNKEIRPGGNY----------TITCVGNTPHLRILKVGKGDSGQYTCQAT 6346
Score = 32.3 bits (72), Expect = 2.8
Identities = 67/287 (23%), Positives = 103/287 (35%), Gaps = 79/287 (27%)
Query: 231 LTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKR 290
L I + SD GE+ C+A D S A+ S V+ + F +L K
Sbjct: 7077 LVINKVDHSDVGEYSCKA-------DNSVGAVAS--SAVLVIKARKLPPFFARKL---KD 7124
Query: 291 LH-TVGEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 349
+H T+G PV F C + VSW + ++ N L + F H
Sbjct: 7125 VHETLGFPVAFECRINGSEP----LQVSW-YKDGVLLKDDAN----LQTSFVH------- 7168
Query: 350 KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTG--EFIDKESKRPKNIPIIVLPL 407
+V L+I Q G+YNC + T + + I E + P +
Sbjct: 7169 -------NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDL----- 7216
Query: 408 KSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDG 467
+SV++A GE F C V T P I W +
Sbjct: 7217 -KPVSVDLAL-------GESGTFKCHV-TGTAP-----------------IKITWAKDNR 7250
Query: 468 TVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 514
++PG +Y +M V+ N+ +L + K D GQY C+ +
Sbjct: 7251 EIRPGGNY---------KMTLVE-NTATLTVLKVGKGDAGQYTCYAS 7287
Score = 31.6 bits (70), Expect = 4.7
Identities = 67/354 (18%), Positives = 122/354 (34%), Gaps = 80/354 (22%)
Query: 676 PVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTH 735
PVT + + +T++E + + L C + S V W
Sbjct: 939 PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSP----TVTW------------------ 976
Query: 736 NSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHV--EEWLLSPN- 792
Y E+ + + + F+ G+ L ++ A DSG + C E +S +
Sbjct: 977 --------YREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSC 1028
Query: 793 YAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMV 852
Y +++EE T ++ + E R V+ VV+ TS+T +
Sbjct: 1029 YLAVQVSEEFEKETTAVTEK-------------FTTEEKRFVESRDVVMTDTSLTEEQAG 1075
Query: 853 EWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQD 912
P + V +L + +G Q N P P VY +
Sbjct: 1076 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGN----------PKPHVY--------WKK 1117
Query: 913 SGTYSCHVEEWLPSPSGMWYKRA-EDTAGQTALTVMR--PDASLQVDTVVPN----ATVS 965
SG +P +G YK + G+ L + D + + VV N + S
Sbjct: 1118 SG---------VPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168
Query: 966 EKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEE 1019
+ D ++ +S Q+ + + + ++PG E E+E E+E+
Sbjct: 1169 ASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQ 1222
Score = 31.6 bits (70), Expect = 4.7
Identities = 66/283 (23%), Positives = 107/283 (37%), Gaps = 60/283 (21%)
Query: 698 QLNCSVKSQTSQNSHFAVL--WYVHKPSDADGKLILKTTHNSAFEY---GT-------YA 745
QL+ V + TS+ + F ++ KPS L+L+ ++ FE GT Y
Sbjct: 4841 QLSNDVGTATSKATLFVKEPPQFIKKPSPV---LVLRNGQSTTFECQITGTPKIRVSWYL 4897
Query: 746 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 805
+ + A + GL + + A V +SG+Y C A S
Sbjct: 4898 DGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR-----------NDAGTASCS 4946
Query: 806 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERE 865
E+ VK+P + +R + + V++ V+LEC V T V W K N R
Sbjct: 4947 IELKVKEPPTFIRELKP---VEVVKYSDVELECEVTG----TPPFEVTWL--KNNREIRS 4997
Query: 866 TVARLSRDATFHYGEQAAKNNLKGRLHLESPSP---GVYRLFIQNVAVQDSGTYSCHVEE 922
+ D + LH+ P G Y+ + N + G+ SC
Sbjct: 4998 SKKYTLTDRVSVF-----------NLHITKCDPSDTGEYQCIVSN----EGGSCSCSTRV 5042
Query: 923 WLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVS 965
L P + K+ E+T TV++ A+ Q TV + +S
Sbjct: 5043 ALKEPPS-FIKKIENTT-----TVLKSSATFQ-STVAGSPPIS 5078
Score = 31.6 bits (70), Expect = 4.7
Identities = 81/414 (19%), Positives = 148/414 (35%), Gaps = 91/414 (21%)
Query: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123
S + E + ++ + +R G + GN+ L I + D+G+Y C
Sbjct: 6287 SADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ-- 6344
Query: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183
+T+ SA++++ P ++ + + E ++L C+++ + V+W
Sbjct: 6345 ATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGES--IQLECKISGS----PEIKVSW 6398
Query: 184 LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGE 243
R D LH S +Y + V L LTI D G+
Sbjct: 6399 FR--------------NDSELHESWKY-NMSFINSVAL---------LTINEASAEDSGD 6434
Query: 244 FYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCI 303
+ CEA + D S V P FT + L G V +C
Sbjct: 6435 YICEAHNGVGD---------ASCSTALTVKAPPV---FTQKPSPVGALK--GSDVILQC- 6479
Query: 304 LEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKI 363
E P F V W + + R ++ +K D+ L I
Sbjct: 6480 -EISGTPP--FEVVWVKDRKQV-----------------RNSKKFKITSKHFDT--SLHI 6517
Query: 364 YHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVIL 423
+L D G+Y+C+ T + T K + P+ + +++ +++I
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVK------------KLSDTSTLIG 6565
Query: 424 EGEDLRFSCSVRTAGRPQGRFSVIWQL----VDRQNRRSNIMWLDRDGTVQPGS 473
+ +LR ++ +P SV+W V R++ + I ++D T+Q GS
Sbjct: 6566 DAVELR---AIVEGFQP---ISVVWLKDRGEVIRESENTRISFIDNIATLQLGS 6613
Score = 31.6 bits (70), Expect = 4.7
Identities = 39/180 (21%), Positives = 72/180 (40%), Gaps = 43/180 (23%)
Query: 606 WGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERT 665
W S+ R + +L I ++AG+Y CV L K +T + E
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE- 11209
Query: 666 SNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDA 725
L +R ++ + + +T+V+ +P+ L+C + N V+W
Sbjct: 11210 ---LPVRFVKTL--------EEEVTVVKGQPLYLSCEL------NKERDVVW------RK 11246
Query: 726 DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE 785
DGK+++ E+ G + V G + +LT+ A+ +D+G+Y VE
Sbjct: 11247 DGKIVV--------------EKPG-----RIVPGVIGLMRALTINDADDTDAGTYTVTVE 11287
Score = 31.2 bits (69), Expect = 6.2
Identities = 59/298 (19%), Positives = 105/298 (35%), Gaps = 56/298 (18%)
Query: 744 YAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVS 803
Y + LR ++ H + +L + +++DSG Y C E EVS
Sbjct: 7995 YKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE-----------NSVGEVS 8043
Query: 804 GRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP- 862
T +TV++ S+ ++ V +C + S + + V W+ K P
Sbjct: 8044 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI----SGSEPISVSWY--KDGKPL 8097
Query: 863 ----------------------ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGV 900
+R + S AT G ++ L + E +P
Sbjct: 8098 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL---ILTEGKNPPF 8154
Query: 901 Y--RLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAED--TAGQTALTVMRPDASLQVD 956
+ RL + V +S + CHV P W K + + + G+ ++ + A L V
Sbjct: 8155 FDIRLAPVDAVVGESADFECHVTGTQPIKVS-WAKDSREIRSGGKYQISYLENSAHLTV- 8212
Query: 957 TVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEERE 1014
V + + Q C V+ +DS A +++ + + L E EE E
Sbjct: 8213 -----LKVDKGDSGQYTCYAVNEVGKDS--CTAQLNIKERLIPPSFTKRLSETVEETE 8263
>gi|14150145 matrix-remodelling associated 8 [Homo sapiens]
Length = 442
Score = 42.4 bits (98), Expect = 0.003
Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 28/216 (12%)
Query: 717 WYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV-SGGLFSLTVQRAEVS 775
W + P + +L SA E Y + R RL+ G FSL ++ E +
Sbjct: 75 WDLRGPGGGPARRLLDLY--SAGEQRVYEARD--RGRLELSASAFDDGNFSLLIRAVEET 130
Query: 776 DSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQ 835
D+G Y C++ ++ + L E ++ R EVT P + + L+V
Sbjct: 131 DAGLYTCNL-------HHHYCHLYESLAVRLEVTDGPPATPAYWDGEKEVLAVARGAPAL 183
Query: 836 LECVVLNRTSI-------TSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLK 888
L CV NR + +Q +V W P P L A+ GE+ A L
Sbjct: 184 LTCV--NRGHVWTDRHVEEAQQVVHWDRQPPGVPHDRADRLLDLYAS---GERRAYGPLF 238
Query: 889 GR----LHLESPSPGVYRLFIQNVAVQDSGTYSCHV 920
R + ++ G + L I+ + V D GTYSCH+
Sbjct: 239 LRDRVAVGADAFERGDFSLRIEPLEVADEGTYSCHL 274
Score = 42.0 bits (97), Expect = 0.003
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 23/183 (12%)
Query: 614 RTRTAIEKAESS---NNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLE 670
R R +E + S+ N L I +T+AG Y C N ++ + L E + LE
Sbjct: 103 RDRGRLELSASAFDDGNFSLLIRAVEETDAGLYTC-------NLHHHYCHLYESLAVRLE 155
Query: 671 IRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHF-----AVLWYVHKPS-- 723
+ P T K L + P L C + + H V W P
Sbjct: 156 VTDGPPATPAYWDGEKEVLAVARGAPALLTCVNRGHVWTDRHVEEAQQVVHWDRQPPGVP 215
Query: 724 -DADGKLILKTTHNSAFEYGTYAEEEGLRARLQ-FERHVSGGLFSLTVQRAEVSDSGSYY 781
D +L+ YG + + FER G FSL ++ EV+D G+Y
Sbjct: 216 HDRADRLLDLYASGERRAYGPLFLRDRVAVGADAFER----GDFSLRIEPLEVADEGTYS 271
Query: 782 CHV 784
CH+
Sbjct: 272 CHL 274
>gi|45331217 zinc finger protein 526 [Homo sapiens]
Length = 670
Score = 41.6 bits (96), Expect = 0.005
Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 4/46 (8%)
Query: 1006 LEEQE----EEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGS 1047
LE++E EE EE++EED++DD++ + A+ VG DAV G E +
Sbjct: 223 LEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDEST 268
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 41.2 bits (95), Expect = 0.006
Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGP-EGSPWEGRLR 1054
E++EEE EEEEEE+++++++ E A +V V GP GS EG R
Sbjct: 747 EDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSER 795
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 40.8 bits (94), Expect = 0.008
Identities = 17/23 (73%), Positives = 20/23 (86%)
Query: 1008 EQEEEREEEEEEDDDDDDDPTER 1030
E+EEE EEEEEE+DDDDDD +R
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDR 1071
Score = 38.1 bits (87), Expect = 0.050
Identities = 16/19 (84%), Positives = 17/19 (89%)
Query: 1007 EEQEEEREEEEEEDDDDDD 1025
EE+EE EEEEEEDDDDDD
Sbjct: 1049 EEEEEAEEEEEEEDDDDDD 1067
Score = 37.4 bits (85), Expect = 0.086
Identities = 15/25 (60%), Positives = 19/25 (76%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERT 1031
EE+E E EEEEE+DDDDD D + +
Sbjct: 1050 EEEEAEEEEEEEDDDDDDSDDRDES 1074
Score = 33.5 bits (75), Expect = 1.2
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 10/62 (16%)
Query: 978 SRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVG 1037
S SS+ S F SSP E EEE EEE+++++++ ++ S G
Sbjct: 1113 SESSESSEFE----------SSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG 1162
Query: 1038 PD 1039
P+
Sbjct: 1163 PE 1164
Score = 32.7 bits (73), Expect = 2.1
Identities = 13/20 (65%), Positives = 16/20 (80%)
Query: 1007 EEQEEEREEEEEEDDDDDDD 1026
E EEE E EEEE+++DDDD
Sbjct: 1046 ESTEEEEEAEEEEEEEDDDD 1065
Score = 32.3 bits (72), Expect = 2.8
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTE 1029
E +EEE EE++++DD DD D +E
Sbjct: 1053 EAEEEEEEEDDDDDDSDDRDESE 1075
>gi|222144231 fibroblast growth factor receptor 2 isoform 3
precursor [Homo sapiens]
Length = 769
Score = 40.4 bits (93), Expect = 0.010
Identities = 68/311 (21%), Positives = 113/311 (36%), Gaps = 73/311 (23%)
Query: 238 PSDQGEFYCEAAEWIQDPDGSWYAMTRKR-----------SEGA--VVNVQPTDKE---F 281
P D G + C A+ + +WY M ++GA V+ +K +
Sbjct: 99 PRDSGLYACTASRTVDSE--TWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYW 156
Query: 282 TVRLETEKRLHTV--GEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSE 339
T + EKRLH V V+FRC +P + W N E
Sbjct: 157 TNTEKMEKRLHAVPAANTVKFRCPAGGNPMP----TMRWLKNGK---------------E 197
Query: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399
F G KV + S+ + + D G Y C V ++ + +R +
Sbjct: 198 FKQEHRIGGYKVRNQHWSLIMESVV---PSDKGNYTCVVENEYGSINHTYHLDVVERSPH 254
Query: 400 IPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSN 459
PI+ L + NAS ++ G D+ F C V + +P + W
Sbjct: 255 RPILQAGLPA--------NASTVVGG-DVEFVCKVYSDAQPH----IQW----------- 290
Query: 460 IMWLDRDGTVQ--PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 517
I ++++G+ G Y + G+ N+ L +FN + D G+Y C V+ ++
Sbjct: 291 IKHVEKNGSKYGPDGLPYLKVLKHSGINSS----NAEVLALFNVTEADAGEYICKVSNYI 346
Query: 518 -RAVDGEWQIV 527
+A W V
Sbjct: 347 GQANQSAWLTV 357
>gi|221316638 fibroblast growth factor receptor 2 isoform 2
precursor [Homo sapiens]
Length = 822
Score = 40.4 bits (93), Expect = 0.010
Identities = 68/311 (21%), Positives = 113/311 (36%), Gaps = 73/311 (23%)
Query: 238 PSDQGEFYCEAAEWIQDPDGSWYAMTRKR-----------SEGA--VVNVQPTDKE---F 281
P D G + C A+ + +WY M ++GA V+ +K +
Sbjct: 99 PRDSGLYACTASRTVDSE--TWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYW 156
Query: 282 TVRLETEKRLHTV--GEPVEFRCILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSE 339
T + EKRLH V V+FRC +P + W N E
Sbjct: 157 TNTEKMEKRLHAVPAANTVKFRCPAGGNPMP----TMRWLKNGK---------------E 197
Query: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399
F G KV + S+ + + D G Y C V ++ + +R +
Sbjct: 198 FKQEHRIGGYKVRNQHWSLIMESVV---PSDKGNYTCVVENEYGSINHTYHLDVVERSPH 254
Query: 400 IPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSN 459
PI+ L + NAS ++ G D+ F C V + +P + W
Sbjct: 255 RPILQAGLPA--------NASTVVGG-DVEFVCKVYSDAQPH----IQW----------- 290
Query: 460 IMWLDRDGTVQ--PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 517
I ++++G+ G Y + G+ N+ L +FN + D G+Y C V+ ++
Sbjct: 291 IKHVEKNGSKYGPDGLPYLKVLKHSGINSS----NAEVLALFNVTEADAGEYICKVSNYI 346
Query: 518 -RAVDGEWQIV 527
+A W V
Sbjct: 347 GQANQSAWLTV 357
>gi|51988914 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 40.4 bits (93), Expect = 0.010
Identities = 36/162 (22%), Positives = 62/162 (38%), Gaps = 18/162 (11%)
Query: 350 KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKS 409
+ A+ + L + +LR EDSGKY CRV+ R + + +R ++ P++
Sbjct: 195 EAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPV 254
Query: 410 SISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
+ +V+ S F C VR+ +P ++ + S I + V
Sbjct: 255 NTTVDFGGTTS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVV 305
Query: 470 QPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYEC 511
P W R + L I +R++D G Y C
Sbjct: 306 LPTGDVWSRPDGSYLN---------KLLITRARQDDAGMYIC 338
Score = 34.7 bits (78), Expect = 0.56
Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 40/190 (21%)
Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVL----PLKSSISVEVA 416
LK+ + +ED+G Y C+ T +++ N ++VL P K S+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132
Query: 417 SNASVILEGEDL---RFS----CSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
S + RF+ R RP G SV + V + R +I W+ D +
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDDQAL 191
Query: 470 QPGSSYWERSSFGGVQMEQVQPNS--FSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI- 526
+ E +P ++L + N R ED G+Y C V+ A++ +++
Sbjct: 192 --------------TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVD 237
Query: 527 VGERRASTPI 536
V +R S P+
Sbjct: 238 VIQRTRSKPV 247
>gi|51988910 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 40.4 bits (93), Expect = 0.010
Identities = 36/162 (22%), Positives = 62/162 (38%), Gaps = 18/162 (11%)
Query: 350 KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKS 409
+ A+ + L + +LR EDSGKY CRV+ R + + +R ++ P++
Sbjct: 195 EAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPV 254
Query: 410 SISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
+ +V+ S F C VR+ +P ++ + S I + V
Sbjct: 255 NTTVDFGGTTS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVV 305
Query: 470 QPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYEC 511
P W R + L I +R++D G Y C
Sbjct: 306 LPTGDVWSRPDGSYLN---------KLLITRARQDDAGMYIC 338
Score = 34.7 bits (78), Expect = 0.56
Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 40/190 (21%)
Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVL----PLKSSISVEVA 416
LK+ + +ED+G Y C+ T +++ N ++VL P K S+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132
Query: 417 SNASVILEGEDL---RFS----CSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
S + RF+ R RP G SV + V + R +I W+ D +
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDDQAL 191
Query: 470 QPGSSYWERSSFGGVQMEQVQPNS--FSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI- 526
+ E +P ++L + N R ED G+Y C V+ A++ +++
Sbjct: 192 --------------TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVD 237
Query: 527 VGERRASTPI 536
V +R S P+
Sbjct: 238 VIQRTRSKPV 247
>gi|51988912 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 40.4 bits (93), Expect = 0.010
Identities = 36/162 (22%), Positives = 62/162 (38%), Gaps = 18/162 (11%)
Query: 350 KVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKS 409
+ A+ + L + +LR EDSGKY CRV+ R + + +R ++ P++
Sbjct: 195 EAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPV 254
Query: 410 SISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
+ +V+ S F C VR+ +P ++ + S I + V
Sbjct: 255 NTTVDFGGTTS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVV 305
Query: 470 QPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYEC 511
P W R + L I +R++D G Y C
Sbjct: 306 LPTGDVWSRPDGSYLN---------KLLITRARQDDAGMYIC 338
Score = 34.7 bits (78), Expect = 0.56
Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 40/190 (21%)
Query: 361 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVL----PLKSSISVEVA 416
LK+ + +ED+G Y C+ T +++ N ++VL P K S+ + +
Sbjct: 84 LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132
Query: 417 SNASVILEGEDL---RFS----CSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTV 469
S + RF+ R RP G SV + V + R +I W+ D +
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDDQAL 191
Query: 470 QPGSSYWERSSFGGVQMEQVQPNS--FSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI- 526
+ E +P ++L + N R ED G+Y C V+ A++ +++
Sbjct: 192 --------------TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVD 237
Query: 527 VGERRASTPI 536
V +R S P+
Sbjct: 238 VIQRTRSKPV 247
>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
Length = 1507
Score = 40.0 bits (92), Expect = 0.013
Identities = 15/23 (65%), Positives = 21/23 (91%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTE 1029
EE+++E EE+EEEDDD+DDD T+
Sbjct: 1400 EEEDQEEEEQEEEDDDEDDDDTD 1422
Score = 37.4 bits (85), Expect = 0.086
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 14/109 (12%)
Query: 920 VEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSR 979
+EE + SP G ++ T +P A++ V + + K DC +
Sbjct: 1322 MEERMKSPFGSSFRTFNATD-------YKPIATIDVKRNIFDLCTDTK-----DCYLAVI 1369
Query: 980 SSQDSRFAVAWYSLRT--KAGGKRSSPGLEEQEEEREEEEEEDDDDDDD 1026
+Q S A+ ++ + G +R + +E+E++ EEE+EE+DDD+DD
Sbjct: 1370 ENQGSMDALNMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDD 1418
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 40.0 bits (92), Expect = 0.013
Identities = 16/40 (40%), Positives = 27/40 (67%)
Query: 998 GGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVG 1037
GG+ S EE+++E E++E+EDDDDD++ + + S G
Sbjct: 506 GGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFG 545
Score = 32.0 bits (71), Expect = 3.6
Identities = 13/24 (54%), Positives = 19/24 (79%)
Query: 1003 SPGLEEQEEEREEEEEEDDDDDDD 1026
S G EE+EEE EEEEEE + ++++
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEE 426
Score = 30.8 bits (68), Expect = 8.0
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTE 1029
EE+EEE EEEEEE+ + +++ E
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEE 428
>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
Length = 550
Score = 40.0 bits (92), Expect = 0.013
Identities = 17/21 (80%), Positives = 18/21 (85%)
Query: 1006 LEEQEEEREEEEEEDDDDDDD 1026
L E +EE EEEEEEDDDDDDD
Sbjct: 524 LPEDDEEEEEEEEEDDDDDDD 544
Score = 39.7 bits (91), Expect = 0.017
Identities = 16/20 (80%), Positives = 18/20 (90%)
Query: 1007 EEQEEEREEEEEEDDDDDDD 1026
E+ EEE EEEEE+DDDDDDD
Sbjct: 526 EDDEEEEEEEEEDDDDDDDD 545
Score = 33.9 bits (76), Expect = 0.95
Identities = 13/21 (61%), Positives = 18/21 (85%)
Query: 1004 PGLEEQEEEREEEEEEDDDDD 1024
P +E+EEE EEE+++DDDDD
Sbjct: 525 PEDDEEEEEEEEEDDDDDDDD 545
Score = 33.5 bits (75), Expect = 1.2
Identities = 16/25 (64%), Positives = 19/25 (76%), Gaps = 5/25 (20%)
Query: 1007 EEQEEE-----REEEEEEDDDDDDD 1026
EE+EEE EEEEEE++DDDDD
Sbjct: 518 EEEEEELPEDDEEEEEEEEEDDDDD 542
Score = 30.8 bits (68), Expect = 8.0
Identities = 14/33 (42%), Positives = 22/33 (66%), Gaps = 5/33 (15%)
Query: 1007 EEQEEERE-----EEEEEDDDDDDDPTERTALL 1034
EE+EEE E EEEEE++++DDD + ++
Sbjct: 516 EEEEEEEELPEDDEEEEEEEEEDDDDDDDDVII 548
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 39.7 bits (91), Expect = 0.017
Identities = 16/22 (72%), Positives = 20/22 (90%)
Query: 1005 GLEEQEEEREEEEEEDDDDDDD 1026
G EE+EEE E+EEEE+DDDDD+
Sbjct: 66 GEEEEEEEEEDEEEEEDDDDDE 87
Score = 39.7 bits (91), Expect = 0.017
Identities = 16/23 (69%), Positives = 20/23 (86%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTE 1029
EE+EEE EE+EEE++DDDDD E
Sbjct: 67 EEEEEEEEEDEEEEEDDDDDELE 89
Score = 35.8 bits (81), Expect = 0.25
Identities = 14/21 (66%), Positives = 19/21 (90%)
Query: 1006 LEEQEEEREEEEEEDDDDDDD 1026
L E+EEE EEE+EE+++DDDD
Sbjct: 65 LGEEEEEEEEEDEEEEEDDDD 85
Score = 34.3 bits (77), Expect = 0.73
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERTA 1032
EE+EE+ EEEE++DDD+ +D E A
Sbjct: 71 EEEEEDEEEEEDDDDDELEDEGEEEA 96
Score = 31.6 bits (70), Expect = 4.7
Identities = 11/27 (40%), Positives = 21/27 (77%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERTAL 1033
EE+E+E EEE+++DD+ +D+ E ++
Sbjct: 72 EEEEDEEEEEDDDDDELEDEGEEEASM 98
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 39.7 bits (91), Expect = 0.017
Identities = 16/22 (72%), Positives = 20/22 (90%)
Query: 1005 GLEEQEEEREEEEEEDDDDDDD 1026
G EE+EEE E+EEEE+DDDDD+
Sbjct: 267 GEEEEEEEEEDEEEEEDDDDDE 288
Score = 39.7 bits (91), Expect = 0.017
Identities = 16/23 (69%), Positives = 20/23 (86%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTE 1029
EE+EEE EE+EEE++DDDDD E
Sbjct: 268 EEEEEEEEEDEEEEEDDDDDELE 290
Score = 35.8 bits (81), Expect = 0.25
Identities = 14/21 (66%), Positives = 19/21 (90%)
Query: 1006 LEEQEEEREEEEEEDDDDDDD 1026
L E+EEE EEE+EE+++DDDD
Sbjct: 266 LGEEEEEEEEEDEEEEEDDDD 286
Score = 34.3 bits (77), Expect = 0.73
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERTA 1032
EE+EE+ EEEE++DDD+ +D E A
Sbjct: 272 EEEEEDEEEEEDDDDDELEDEGEEEA 297
Score = 31.6 bits (70), Expect = 4.7
Identities = 11/27 (40%), Positives = 21/27 (77%)
Query: 1007 EEQEEEREEEEEEDDDDDDDPTERTAL 1033
EE+E+E EEE+++DD+ +D+ E ++
Sbjct: 273 EEEEDEEEEEDDDDDELEDEGEEEASM 299
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,965,193
Number of Sequences: 37866
Number of extensions: 2192231
Number of successful extensions: 25833
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 271
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 17876
Number of HSP's gapped (non-prelim): 5000
length of query: 1194
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1080
effective length of database: 13,930,794
effective search space: 15045257520
effective search space used: 15045257520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.