Guide to the Human Genome
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Search of human proteins with 55925574

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55925574 adenosine monophosphate deaminase 2 (isoform L)
isoform 3 [Homo sapiens]
         (760 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isof...  1544   0.0  
gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isof...  1527   0.0  
gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isof...  1527   0.0  
gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo ...   776   0.0  
gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo...   776   0.0  
gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo...   776   0.0  
gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo...   728   0.0  
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo...    37   0.068
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo...    37   0.068
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo...    37   0.068
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo...    37   0.068
gi|207113130 pseudouridylate synthase 10 [Homo sapiens]                36   0.12 
gi|29029552 cat eye syndrome critical region protein 1 isoform b...    36   0.12 
gi|29029550 cat eye syndrome critical region protein 1 isoform a...    36   0.12 
gi|221139761 zinc finger protein 853 [Homo sapiens]                    35   0.20 
gi|148746195 trichohyalin [Homo sapiens]                               34   0.44 
gi|7705415 hook homolog 1 [Homo sapiens]                               32   2.2  
gi|16262452 cingulin [Homo sapiens]                                    32   2.9  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               32   2.9  
gi|62422577 neurobeachin [Homo sapiens]                                31   3.7  
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo...    31   3.7  
gi|21735548 centrosomal protein 2 [Homo sapiens]                       31   4.9  
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      31   4.9  
gi|32307161 cullin 1 [Homo sapiens]                                    31   4.9  
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               31   4.9  
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]         31   4.9  
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       31   4.9  
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    30   6.4  
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    30   6.4  
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    30   6.4  

>gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isoform
           3 [Homo sapiens]
          Length = 760

 Score = 1544 bits (3998), Expect = 0.0
 Identities = 760/760 (100%), Positives = 760/760 (100%)

Query: 1   MLTFLPSPQELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILL 60
           MLTFLPSPQELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILL
Sbjct: 1   MLTFLPSPQELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILL 60

Query: 61  RAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLD 120
           RAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLD
Sbjct: 61  RAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLD 120

Query: 121 AAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHP 180
           AAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHP
Sbjct: 121 AAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHP 180

Query: 181 PALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADV 240
           PALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADV
Sbjct: 181 PALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADV 240

Query: 241 NVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHI 300
           NVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHI
Sbjct: 241 NVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHI 300

Query: 301 HASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHA 360
           HASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHA
Sbjct: 301 HASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHA 360

Query: 361 DRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAEL 420
           DRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAEL
Sbjct: 361 DRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAEL 420

Query: 421 RLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFL 480
           RLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFL
Sbjct: 421 RLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFL 480

Query: 481 PLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYY 540
           PLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYY
Sbjct: 481 PLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYY 540

Query: 541 LYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVL 600
           LYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVL
Sbjct: 541 LYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVL 600

Query: 601 QYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEE 660
           QYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEE
Sbjct: 601 QYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEE 660

Query: 661 YSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIR 720
           YSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIR
Sbjct: 661 YSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIR 720

Query: 721 VGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ 760
           VGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
Sbjct: 721 VGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ 760


>gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isoform
           2 [Homo sapiens]
          Length = 798

 Score = 1527 bits (3953), Expect = 0.0
 Identities = 751/752 (99%), Positives = 752/752 (100%)

Query: 9   QELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK 68
           +ELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK
Sbjct: 47  EELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK 106

Query: 69  TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA 128
           TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA
Sbjct: 107 TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA 166

Query: 129 LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY 188
           LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY
Sbjct: 167 LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY 226

Query: 189 EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII 248
           EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII
Sbjct: 227 EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII 286

Query: 249 NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ 308
           NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ
Sbjct: 287 NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ 346

Query: 309 KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF 368
           KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF
Sbjct: 347 KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF 406

Query: 369 DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS 428
           DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS
Sbjct: 407 DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS 466

Query: 429 RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH 488
           RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH
Sbjct: 467 RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH 526

Query: 489 PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM 548
           PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM
Sbjct: 527 PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM 586

Query: 549 AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ 608
           AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ
Sbjct: 587 AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ 646

Query: 609 IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW 668
           IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW
Sbjct: 647 IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW 706

Query: 669 KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL 728
           KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL
Sbjct: 707 KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL 766

Query: 729 CQELALITQAVQSEMLETIPEEAGITMSPGPQ 760
           CQELALITQAVQSEMLETIPEEAGITMSPGPQ
Sbjct: 767 CQELALITQAVQSEMLETIPEEAGITMSPGPQ 798


>gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isoform
           1 [Homo sapiens]
          Length = 879

 Score = 1527 bits (3953), Expect = 0.0
 Identities = 751/752 (99%), Positives = 752/752 (100%)

Query: 9   QELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK 68
           +ELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK
Sbjct: 128 EELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK 187

Query: 69  TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA 128
           TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA
Sbjct: 188 TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRA 247

Query: 129 LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY 188
           LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY
Sbjct: 248 LFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPY 307

Query: 189 EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII 248
           EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII
Sbjct: 308 EHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALII 367

Query: 249 NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ 308
           NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ
Sbjct: 368 NGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQ 427

Query: 309 KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF 368
           KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF
Sbjct: 428 KHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRF 487

Query: 369 DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS 428
           DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS
Sbjct: 488 DKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRS 547

Query: 429 RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH 488
           RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH
Sbjct: 548 RDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH 607

Query: 489 PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM 548
           PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM
Sbjct: 608 PASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANM 667

Query: 549 AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ 608
           AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ
Sbjct: 668 AMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQ 727

Query: 609 IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW 668
           IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW
Sbjct: 728 IGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVW 787

Query: 669 KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL 728
           KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL
Sbjct: 788 KLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETL 847

Query: 729 CQELALITQAVQSEMLETIPEEAGITMSPGPQ 760
           CQELALITQAVQSEMLETIPEEAGITMSPGPQ
Sbjct: 848 CQELALITQAVQSEMLETIPEEAGITMSPGPQ 879


>gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo
           sapiens]
          Length = 776

 Score =  776 bits (2003), Expect = 0.0
 Identities = 400/761 (52%), Positives = 531/761 (69%), Gaps = 39/761 (5%)

Query: 9   QELFTRSLAESELRSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDF 66
           +++F + L E + + A   F  PE+ PI Q E + + L++++++   +E     + K+ F
Sbjct: 31  EKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET---AKRKKSF 87

Query: 67  LKTDSDS-DLQLYKEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGE 108
               S S  LQ+  +Q  +G                G  SL         EFQRVTISG+
Sbjct: 88  KMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGD 147

Query: 109 EKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG- 167
              G+   D   AAKS+ +AL IREKY  L+   F   T +YL        +T   E+G 
Sbjct: 148 YCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGL 204

Query: 168 PDTPVSADAPVHPPALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEV 226
           PD         HPP L Q  PY  C     P +L   + M  G++ VY  ++  EH    
Sbjct: 205 PD--------FHPPPLPQEDPY--CLDDAPP-NLDYLVHMQGGILFVYDNKKMLEHQEPH 253

Query: 227 ELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVP 286
            LPYPDL+ +  D++ ++ALI +GP K++C+RRL +L SKF +H +LNEM E    K  P
Sbjct: 254 SLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNP 313

Query: 287 HRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNL 346
           HRDFYN+RKVDTHIHA++CMNQKHLLRFIK   +   +  V  ++GR+ TLR+VF+ +++
Sbjct: 314 HRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHM 373

Query: 347 TAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEV 406
             YDL+VD+LDVHA R TFHRFDKFN+KYNP+G S LR++++KT+N + G+YFA ++KEV
Sbjct: 374 DPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEV 433

Query: 407 MSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKG 466
             +LEESKYQ +E RLSIYGRS +EW  LA W + H+V+SPN+RW++QVPR++D++R+K 
Sbjct: 434 ARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKK 493

Query: 467 QLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLP 526
            L NF +MLENIFLPLF+AT++P  H ELHLFL++V GFDSVDDESK  +H+F+ +SP P
Sbjct: 494 LLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNP 553

Query: 527 EAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAE 586
           + W  E NPPY+YYLYY +AN+ +LN+LRR+RG  TF+ RPHCGEAG I HLVSAF+ A+
Sbjct: 554 DVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTAD 613

Query: 587 NISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDD 646
           NISHGLLL+K+PVLQYLYYLAQI IAMSPLSNNSLFL Y +NPL E+L +GL VSLSTDD
Sbjct: 614 NISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDD 673

Query: 647 PLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGP 706
           P+QFH+TKE LMEEY+IA QVWKLS+CD+CE+ARNSVL SG SH+ K  +LG NY KEGP
Sbjct: 674 PMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGP 733

Query: 707 EGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETI 747
           EGNDIR+TNV  IR+ +RYETLC EL+ ++ A++SE +  +
Sbjct: 734 EGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITAL 774


>gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo
           sapiens]
          Length = 774

 Score =  776 bits (2003), Expect = 0.0
 Identities = 400/761 (52%), Positives = 531/761 (69%), Gaps = 39/761 (5%)

Query: 9   QELFTRSLAESELRSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDF 66
           +++F + L E + + A   F  PE+ PI Q E + + L++++++   +E     + K+ F
Sbjct: 29  EKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET---AKRKKSF 85

Query: 67  LKTDSDS-DLQLYKEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGE 108
               S S  LQ+  +Q  +G                G  SL         EFQRVTISG+
Sbjct: 86  KMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGD 145

Query: 109 EKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG- 167
              G+   D   AAKS+ +AL IREKY  L+   F   T +YL        +T   E+G 
Sbjct: 146 YCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGL 202

Query: 168 PDTPVSADAPVHPPALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEV 226
           PD         HPP L Q  PY  C     P +L   + M  G++ VY  ++  EH    
Sbjct: 203 PD--------FHPPPLPQEDPY--CLDDAPP-NLDYLVHMQGGILFVYDNKKMLEHQEPH 251

Query: 227 ELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVP 286
            LPYPDL+ +  D++ ++ALI +GP K++C+RRL +L SKF +H +LNEM E    K  P
Sbjct: 252 SLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNP 311

Query: 287 HRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNL 346
           HRDFYN+RKVDTHIHA++CMNQKHLLRFIK   +   +  V  ++GR+ TLR+VF+ +++
Sbjct: 312 HRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHM 371

Query: 347 TAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEV 406
             YDL+VD+LDVHA R TFHRFDKFN+KYNP+G S LR++++KT+N + G+YFA ++KEV
Sbjct: 372 DPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEV 431

Query: 407 MSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKG 466
             +LEESKYQ +E RLSIYGRS +EW  LA W + H+V+SPN+RW++QVPR++D++R+K 
Sbjct: 432 ARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKK 491

Query: 467 QLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLP 526
            L NF +MLENIFLPLF+AT++P  H ELHLFL++V GFDSVDDESK  +H+F+ +SP P
Sbjct: 492 LLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNP 551

Query: 527 EAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAE 586
           + W  E NPPY+YYLYY +AN+ +LN+LRR+RG  TF+ RPHCGEAG I HLVSAF+ A+
Sbjct: 552 DVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTAD 611

Query: 587 NISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDD 646
           NISHGLLL+K+PVLQYLYYLAQI IAMSPLSNNSLFL Y +NPL E+L +GL VSLSTDD
Sbjct: 612 NISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDD 671

Query: 647 PLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGP 706
           P+QFH+TKE LMEEY+IA QVWKLS+CD+CE+ARNSVL SG SH+ K  +LG NY KEGP
Sbjct: 672 PMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGP 731

Query: 707 EGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETI 747
           EGNDIR+TNV  IR+ +RYETLC EL+ ++ A++SE +  +
Sbjct: 732 EGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITAL 772


>gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo
           sapiens]
          Length = 767

 Score =  776 bits (2003), Expect = 0.0
 Identities = 400/761 (52%), Positives = 531/761 (69%), Gaps = 39/761 (5%)

Query: 9   QELFTRSLAESELRSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDF 66
           +++F + L E + + A   F  PE+ PI Q E + + L++++++   +E     + K+ F
Sbjct: 22  EKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET---AKRKKSF 78

Query: 67  LKTDSDS-DLQLYKEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGE 108
               S S  LQ+  +Q  +G                G  SL         EFQRVTISG+
Sbjct: 79  KMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGD 138

Query: 109 EKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG- 167
              G+   D   AAKS+ +AL IREKY  L+   F   T +YL        +T   E+G 
Sbjct: 139 YCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGL 195

Query: 168 PDTPVSADAPVHPPALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEV 226
           PD         HPP L Q  PY  C     P +L   + M  G++ VY  ++  EH    
Sbjct: 196 PD--------FHPPPLPQEDPY--CLDDAPP-NLDYLVHMQGGILFVYDNKKMLEHQEPH 244

Query: 227 ELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVP 286
            LPYPDL+ +  D++ ++ALI +GP K++C+RRL +L SKF +H +LNEM E    K  P
Sbjct: 245 SLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNP 304

Query: 287 HRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNL 346
           HRDFYN+RKVDTHIHA++CMNQKHLLRFIK   +   +  V  ++GR+ TLR+VF+ +++
Sbjct: 305 HRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHM 364

Query: 347 TAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEV 406
             YDL+VD+LDVHA R TFHRFDKFN+KYNP+G S LR++++KT+N + G+YFA ++KEV
Sbjct: 365 DPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEV 424

Query: 407 MSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKG 466
             +LEESKYQ +E RLSIYGRS +EW  LA W + H+V+SPN+RW++QVPR++D++R+K 
Sbjct: 425 ARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKK 484

Query: 467 QLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLP 526
            L NF +MLENIFLPLF+AT++P  H ELHLFL++V GFDSVDDESK  +H+F+ +SP P
Sbjct: 485 LLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNP 544

Query: 527 EAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAE 586
           + W  E NPPY+YYLYY +AN+ +LN+LRR+RG  TF+ RPHCGEAG I HLVSAF+ A+
Sbjct: 545 DVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTAD 604

Query: 587 NISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDD 646
           NISHGLLL+K+PVLQYLYYLAQI IAMSPLSNNSLFL Y +NPL E+L +GL VSLSTDD
Sbjct: 605 NISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDD 664

Query: 647 PLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGP 706
           P+QFH+TKE LMEEY+IA QVWKLS+CD+CE+ARNSVL SG SH+ K  +LG NY KEGP
Sbjct: 665 PMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGP 724

Query: 707 EGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETI 747
           EGNDIR+TNV  IR+ +RYETLC EL+ ++ A++SE +  +
Sbjct: 725 EGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITAL 765


>gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo
           sapiens]
          Length = 747

 Score =  728 bits (1878), Expect = 0.0
 Identities = 356/644 (55%), Positives = 471/644 (73%), Gaps = 13/644 (2%)

Query: 99  EFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQL-AEK 157
           +FQRV I+G+   GV   D     K + RAL IREKYM  S Q F  T  +YL+ +  E 
Sbjct: 114 DFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEA 173

Query: 158 PLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRR 217
            +   ++            PV  P +++   +      +P +LG  L+M  GVV+VY   
Sbjct: 174 WVANESFY-----------PVFTPPVKKGE-DPFRTDNLPENLGYHLKMKDGVVYVYPNE 221

Query: 218 EPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMK 277
                     LPYP+L  F+ D+N L+ALI  GP+K++ +RRL++LSSKFQ+H +LNEM 
Sbjct: 222 AAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMD 281

Query: 278 ELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTL 337
           EL   K  PHRDFYN RKVDTHIHA++CMNQKHLLRFIK++ +   + +V+  + +  TL
Sbjct: 282 ELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTL 341

Query: 338 REVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGK 397
           +E+F  + +  YDL+VD+LDVHA R TF RFDKFN KYNP+G S LR++++KTDN ++G+
Sbjct: 342 KELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGE 401

Query: 398 YFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPR 457
           YFA IIKEV +DL E+KYQ+AE RLSIYGRS DEW KL+ W V +R+H PN+ W++QVPR
Sbjct: 402 YFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPR 461

Query: 458 LFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENH 517
           ++DV+R+K  L +F +MLENIF+P+FEAT++P + PEL +FL+H+ GFDSVDDESK   H
Sbjct: 462 IYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGH 521

Query: 518 VFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHH 577
           +F+ +SP P+ W  E NP Y YY YY +AN+ +LN LR++RG +TF+ RPHCGEAG + H
Sbjct: 522 MFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTH 581

Query: 578 LVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRG 637
           L++AFM+A++ISHGL L+K+PVLQYL++LAQI IAMSPLSNNSLFL Y +NP  ++L +G
Sbjct: 582 LMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKG 641

Query: 638 LMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWL 697
           LM+SLSTDDP+QFHFTKEPLMEEY+IA QV+KLS+CDMCE+ARNSVL  G SH+ K  +L
Sbjct: 642 LMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFL 701

Query: 698 GPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQS 741
           G NY +EGP GNDIRRTNV  IR+ YRYET C EL LI + ++S
Sbjct: 702 GDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKS 745


>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
           sapiens]
          Length = 902

 Score = 37.0 bits (84), Expect = 0.068
 Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 21/124 (16%)

Query: 56  PDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPF 115
           PD++LR   D   +DS+SDL   K     + D S R            T  GE K  VPF
Sbjct: 64  PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARR-----------TSHGEPKSAVPF 112

Query: 116 TDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQ--QLAEKPL-ETRTYEQGPDTPV 172
              L    +       +  Y+   L+        Y +    A  PL   R +  GP TPV
Sbjct: 113 NQYLPNKSN-------QTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPV 165

Query: 173 SADA 176
           S DA
Sbjct: 166 SDDA 169


>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
           sapiens]
          Length = 1056

 Score = 37.0 bits (84), Expect = 0.068
 Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 21/124 (16%)

Query: 56  PDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPF 115
           PD++LR   D   +DS+SDL   K     + D S R            T  GE K  VPF
Sbjct: 218 PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARR-----------TSHGEPKSAVPF 266

Query: 116 TDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQ--QLAEKPL-ETRTYEQGPDTPV 172
              L    +       +  Y+   L+        Y +    A  PL   R +  GP TPV
Sbjct: 267 NQYLPNKSN-------QTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPV 319

Query: 173 SADA 176
           S DA
Sbjct: 320 SDDA 323


>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
           sapiens]
          Length = 1057

 Score = 37.0 bits (84), Expect = 0.068
 Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 21/124 (16%)

Query: 56  PDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPF 115
           PD++LR   D   +DS+SDL   K     + D S R            T  GE K  VPF
Sbjct: 218 PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARR-----------TSHGEPKSAVPF 266

Query: 116 TDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQ--QLAEKPL-ETRTYEQGPDTPV 172
              L    +       +  Y+   L+        Y +    A  PL   R +  GP TPV
Sbjct: 267 NQYLPNKSN-------QTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPV 319

Query: 173 SADA 176
           S DA
Sbjct: 320 SDDA 323


>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
           sapiens]
          Length = 1083

 Score = 37.0 bits (84), Expect = 0.068
 Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 21/124 (16%)

Query: 56  PDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPF 115
           PD++LR   D   +DS+SDL   K     + D S R            T  GE K  VPF
Sbjct: 218 PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARR-----------TSHGEPKSAVPF 266

Query: 116 TDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQ--QLAEKPL-ETRTYEQGPDTPV 172
              L    +       +  Y+   L+        Y +    A  PL   R +  GP TPV
Sbjct: 267 NQYLPNKSN-------QTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPV 319

Query: 173 SADA 176
           S DA
Sbjct: 320 SDDA 323


>gi|207113130 pseudouridylate synthase 10 [Homo sapiens]
          Length = 529

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 273 LNEMKELAAQKKVP----HRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVH 328
           LN++K+L   +K P    HR    +R    H   +  +++ H    +K     +++E VH
Sbjct: 432 LNDIKDLKIDQKTPLRVLHRRPLAVRARVIHFMETQYVDEHHFRLHLKTQAGTYIKEFVH 491

Query: 329 VEQGREQTLREVFESMNLTAYDLSVDTLDVHAD 361
            + GR  T   +   MN+TA  L +D   V  D
Sbjct: 492 GDFGR--TKPNIGSLMNVTADILELDVESVDVD 522


>gi|29029552 cat eye syndrome critical region protein 1 isoform b
           [Homo sapiens]
          Length = 270

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 577 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEY 633
           +++ A ML    I HG  L K P ++   +   I I + P+SN  L L      +P+   
Sbjct: 129 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 188

Query: 634 LSRGLMVSLSTDDPLQF 650
           ++ G  + +S+DDP  F
Sbjct: 189 MATGHPMVISSDDPAMF 205


>gi|29029550 cat eye syndrome critical region protein 1 isoform a
           precursor [Homo sapiens]
          Length = 511

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 577 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEY 633
           +++ A ML    I HG  L K P ++   +   I I + P+SN  L L      +P+   
Sbjct: 370 NILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATL 429

Query: 634 LSRGLMVSLSTDDPLQF 650
           ++ G  + +S+DDP  F
Sbjct: 430 MATGHPMVISSDDPAMF 446


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 38/189 (20%), Positives = 80/189 (42%), Gaps = 13/189 (6%)

Query: 16  LAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDL 75
           L   + +  P +  E+  ++Q +E+ Q  + Q  Q ++ +  +  + ++  L       L
Sbjct: 152 LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211

Query: 76  Q---LYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIR 132
           Q   L ++Q + Q  +  ++++ L+++ Q + +  +   G     LL   ++ ++   + 
Sbjct: 212 QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQ---GQLQQQLLQQQQAQLQQQLLE 268

Query: 133 EKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCE 192
           ++   L  Q      +  LQQ  ++ L  +  EQ           + PP LE    E  E
Sbjct: 269 QQQAQLQ-QQLLLQQQEQLQQQQQQQLLQQQQEQ------LQQQQLQPPPLEPEEEEEVE 321

Query: 193 PSTMPGDLG 201
              MP DLG
Sbjct: 322 LELMPVDLG 330


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 34.3 bits (77), Expect = 0.44
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 30  EESPIEQLEERRQRLERQISQDVKLEPDILL----RAKQDFLKTDSDS--DLQLYKEQGE 83
           EE   EQ EERR++ ER+  Q+ + E  +      R +Q   +   +   + QL +EQ E
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370

Query: 84  GQGDRSLRERDVLEREFQ 101
            + ++ LR    L RE Q
Sbjct: 371 ERREQQLRREQQLRREQQ 388



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 18/110 (16%)

Query: 18   ESELRSAPYE--FPEESPIEQLEE----RRQRLERQISQDVKLEPDILLRAKQDFLKTDS 71
            E +LR    E  F EE  + Q  E    RRQ   R+I ++ +L P+   R +Q   + + 
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE---REEQQLRRQER 1769

Query: 72   D----SDLQLYKEQGEGQ-----GDRSLRERDVLEREFQRVTISGEEKCG 112
            D     + QL +E+ E Q      DR  RE + L +E +   +  +++ G
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG 1819



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 3/87 (3%)

Query: 16  LAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDL 75
           L E E R       ++   EQ E R QRL+RQ  ++ +L+    LR++Q   +   +   
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQ-EEEERLQQ--RLRSEQQLRREQEERRE 547

Query: 76  QLYKEQGEGQGDRSLRERDVLEREFQR 102
           QL K + E + ++  RE+ +   + +R
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEER 574



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 7/92 (7%)

Query: 9    QELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKL--EPDILLRAKQDF 66
            QEL  +   E E++    +   E P ++   RRQ LERQ  ++ +L  E + LLR +Q+ 
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKR---RRQELERQYREEEELQQEEEQLLREEQE- 1189

Query: 67   LKTDSDSDLQLYKEQGEGQGDRSLRERDVLER 98
             K   + + Q  +E+   +  R  R RD  +R
Sbjct: 1190 -KRRQERERQYREEEELQRQKRKQRYRDEDQR 1220



 Score = 30.0 bits (66), Expect = 8.3
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 20/112 (17%)

Query: 9    QELFTRSLAESELRSAPYEFPEESPIEQLEE----------RRQRLERQISQDVKL--EP 56
            ++L      +  L+    ++ EE  ++Q EE          RRQ LERQ  ++ +L  E 
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090

Query: 57   DILLRAKQDFLKTD-------SDSDLQLYKEQGEGQGDRSLRERDVLEREFQ 101
            + LLR + +  +          + +LQ  +EQ   + +R  R R  LER+++
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-EREKRRRQELERQYR 1141


>gi|7705415 hook homolog 1 [Homo sapiens]
          Length = 728

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 21/101 (20%), Positives = 51/101 (50%), Gaps = 1/101 (0%)

Query: 9   QELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLK 68
           +E+F R   E+++     E  E   IE+L+E+ ++  R+++ +++ E  +     ++  +
Sbjct: 464 REVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMN-ELETEQRLSKERIRELQQ 522

Query: 69  TDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEE 109
              D    L ++  + +G+ S + +  LE   +++T   EE
Sbjct: 523 QIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEE 563


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 31.6 bits (70), Expect = 2.9
 Identities = 18/63 (28%), Positives = 37/63 (58%)

Query: 36  QLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDV 95
           ++EE +++L+ ++ +  KLEP  +   +Q   KT+  S LQ   E+ +G+  +S +E   
Sbjct: 367 KVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQN 426

Query: 96  LER 98
           ++R
Sbjct: 427 MKR 429


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 31.6 bits (70), Expect = 2.9
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 6/105 (5%)

Query: 9    QELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQ-DVKLEPDILLRAKQDFL 67
            +EL  + L  S++ S      E+  + QL++  + L+ QI     KLE +   RAK +  
Sbjct: 1090 EELRKKELELSQMNSKVEN--EKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERE 1147

Query: 68   KTDSDSDLQLYKEQGEGQGDRSLRERDVL---EREFQRVTISGEE 109
            + D   DL    E+ E  G  SL + ++    E +FQ++    EE
Sbjct: 1148 RADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEE 1192


>gi|62422577 neurobeachin [Homo sapiens]
          Length = 2946

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 514  PENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGE 571
            P+  VF  E    E W ++ +PPY Y  +Y+ A  + L+ L R   F TF L  + G+
Sbjct: 2352 PKRAVFYAERY--ETWEDDQSPPYHYNTHYSTAT-STLSWLVRIEPFTTFFLNANDGK 2406


>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
           sapiens]
          Length = 890

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 11/64 (17%)

Query: 56  PDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPF 115
           PD++LR   D   +DS+SDL   K     + D S R            T  GE K  VPF
Sbjct: 64  PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARR-----------TSHGEPKSAVPF 112

Query: 116 TDLL 119
              L
Sbjct: 113 NQYL 116


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 8/89 (8%)

Query: 30   EESPIEQLEERRQRLERQIS---QDVKLEPDIL--LRAKQDFLKTD---SDSDLQLYKEQ 81
            + S I  LE     L R++    Q+VK + + +  L+ +++ L  D    D +L L KE+
Sbjct: 1607 QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKER 1666

Query: 82   GEGQGDRSLRERDVLEREFQRVTISGEEK 110
             +   D+  R+  +LE + +++ +S  E+
Sbjct: 1667 IQVLEDQRTRQTKILEEDLEQIKLSLRER 1695


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 4/106 (3%)

Query: 6   PSPQELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQD 65
           P P++ ++  LAE  +R+   + PEE P  +   R+  ++RQIS    LE   +  +K +
Sbjct: 225 PMPRD-YSPELAEL-IRTMLSKRPEERPSVRSILRQPYIKRQIS--FFLEATKIKTSKNN 280

Query: 66  FLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKC 111
               DS S        GE + +  +     L  E  +  I GE KC
Sbjct: 281 IKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKC 326


>gi|32307161 cullin 1 [Homo sapiens]
          Length = 776

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 22/156 (14%)

Query: 4   FLPSPQELFTRSLAESELRSAPYEFPEESPIEQLEERRQ-----------RLERQISQD- 51
           FL   +  +TR   E   ++   E+ +++    LEE+R+            L R+  Q  
Sbjct: 236 FLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVL 295

Query: 52  VKLEPDILLRAKQDFLKTDSDSDL----QLYKEQGEGQGDRSLRERDVLEREFQRVTISG 107
           ++   +I     Q+ L  D + DL     L     +G G+     + +LE       ++ 
Sbjct: 296 IEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGEL----KKLLETHIHNQGLAA 351

Query: 108 EEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSF 143
            EKCG     L D    V   L + +KY AL + +F
Sbjct: 352 IEKCGE--AALNDPKMYVQTVLDVHKKYNALVMSAF 385


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 13/52 (25%), Positives = 29/52 (55%)

Query: 27  EFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLY 78
           + P    +++LE+R + L     +D K E ++L   ++++ KT +  ++ LY
Sbjct: 610 KIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIMLY 661


>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
          Length = 439

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 4/107 (3%)

Query: 30  EESPIEQLE-ERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDR 88
           EE  I+  E ERR+ + RQ +Q+ K E   ++  + +    +       Y+E  + + + 
Sbjct: 136 EEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEM 195

Query: 89  SLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKY 135
             R + V  R+  RVT+   E   +   +L   AK +      R KY
Sbjct: 196 EPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEE---RRKY 239


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 687 GFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQ-ELALITQAVQSEMLE 745
           GF   ++    GP++T++ P   D+   +VP + V Y  E   Q +LAL      +E L 
Sbjct: 228 GFEEHLQEAAQGPHFTQQDPAAPDV--GSVPPVEVVYSQEPGAQPDLALARSLPPAEELP 285

Query: 746 T-IPEEAGITM-----SPGP 759
              P+ AG  +     SPGP
Sbjct: 286 VETPKRAGAEVSWEVSSPGP 305


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 30.4 bits (67), Expect = 6.4
 Identities = 37/146 (25%), Positives = 61/146 (41%), Gaps = 16/146 (10%)

Query: 30  EESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRS 89
           EE   + L ER++R+E Q  Q  +LE     R +++  K       + Y+EQ   + +R 
Sbjct: 381 EEHKRQLLAERQKRIEEQKEQRRRLEEQ--QRREKELRKQQEREQRRHYEEQMRREEERR 438

Query: 90  LRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALF-------IREKYMALSLQS 142
             E    E+E+ R  +  E++      ++L       +AL        + E+  A  LQ 
Sbjct: 439 RAEH---EQEYIRRQLEEEQR----QLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR 491

Query: 143 FCPTTRRYLQQLAEKPLETRTYEQGP 168
                R YL  L  +  E R  E+ P
Sbjct: 492 QLKQERDYLVSLQHQRQEQRPVEKKP 517


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 30.4 bits (67), Expect = 6.4
 Identities = 37/146 (25%), Positives = 61/146 (41%), Gaps = 16/146 (10%)

Query: 30  EESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRS 89
           EE   + L ER++R+E Q  Q  +LE     R +++  K       + Y+EQ   + +R 
Sbjct: 381 EEHKRQLLAERQKRIEEQKEQRRRLEEQ--QRREKELRKQQEREQRRHYEEQMRREEERR 438

Query: 90  LRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALF-------IREKYMALSLQS 142
             E    E+E+ R  +  E++      ++L       +AL        + E+  A  LQ 
Sbjct: 439 RAEH---EQEYIRRQLEEEQR----QLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR 491

Query: 143 FCPTTRRYLQQLAEKPLETRTYEQGP 168
                R YL  L  +  E R  E+ P
Sbjct: 492 QLKQERDYLVSLQHQRQEQRPVEKKP 517


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 30.4 bits (67), Expect = 6.4
 Identities = 37/146 (25%), Positives = 61/146 (41%), Gaps = 16/146 (10%)

Query: 30  EESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRS 89
           EE   + L ER++R+E Q  Q  +LE     R +++  K       + Y+EQ   + +R 
Sbjct: 381 EEHKRQLLAERQKRIEEQKEQRRRLEEQ--QRREKELRKQQEREQRRHYEEQMRREEERR 438

Query: 90  LRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALF-------IREKYMALSLQS 142
             E    E+E+ R  +  E++      ++L       +AL        + E+  A  LQ 
Sbjct: 439 RAEH---EQEYIRRQLEEEQR----QLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR 491

Query: 143 FCPTTRRYLQQLAEKPLETRTYEQGP 168
                R YL  L  +  E R  E+ P
Sbjct: 492 QLKQERDYLVSLQHQRQEQRPVEKKP 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,066,279
Number of Sequences: 37866
Number of extensions: 1411527
Number of successful extensions: 4427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 4366
Number of HSP's gapped (non-prelim): 80
length of query: 760
length of database: 18,247,518
effective HSP length: 110
effective length of query: 650
effective length of database: 14,082,258
effective search space: 9153467700
effective search space used: 9153467700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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