Search of human proteins with 55749600

Search of human proteins with 55749600

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749600 spire homolog 2 [Homo sapiens]
         (714 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749600 spire homolog 2 [Homo sapiens]                           1446   0.0  
gi|191250771 spire homolog 1 isoform b [Homo sapiens]                 508   e-144
gi|191250773 spire homolog 1 isoform a [Homo sapiens]                 507   e-143
gi|191250775 spire homolog 1 isoform c [Homo sapiens]                 454   e-127
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l...    45   3e-04
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l...    45   3e-04
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l...    44   4e-04
gi|169208016 PREDICTED: similar to golgi autoantigen, golgin sub...    44   4e-04
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l...    41   0.003
gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo s...    41   0.003
gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo s...    41   0.004
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l...    40   0.006
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l...    40   0.006
gi|113425119 PREDICTED: similar to golgi autoantigen, golgin sub...    40   0.006
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    40   0.008
gi|239750798 PREDICTED: similar to hect domain and RLD 2 [Homo s...    39   0.013
gi|122692281 hypothetical protein LOC645369 [Homo sapiens]             39   0.022
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l...    38   0.029
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly...    38   0.037
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein...    37   0.049
gi|169171485 PREDICTED: hypothetical protein [Homo sapiens]            37   0.064
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein...    35   0.19 
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                35   0.24 
gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.32 
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.32 
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.32 
gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]     35   0.32 
gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]     35   0.32 
gi|40538728 pleckstrin homology domain containing, family M (wit...    34   0.41 
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.41 

>gi|55749600 spire homolog 2 [Homo sapiens]
          Length = 714

 Score = 1446 bits (3742), Expect = 0.0
 Identities = 714/714 (100%), Positives = 714/714 (100%)

Query: 1   MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLR 60
           MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLR
Sbjct: 1   MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLR 60

Query: 61  DTGDLLLRGDGSVGAREPEAAEPATMVVPLASSEAQTVQSLGFAIYRALDWGLDESEERE 120
           DTGDLLLRGDGSVGAREPEAAEPATMVVPLASSEAQTVQSLGFAIYRALDWGLDESEERE
Sbjct: 61  DTGDLLLRGDGSVGAREPEAAEPATMVVPLASSEAQTVQSLGFAIYRALDWGLDESEERE 120

Query: 121 LSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLT 180
           LSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLT
Sbjct: 121 LSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLT 180

Query: 181 DPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHT 240
           DPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHT
Sbjct: 181 DPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHT 240

Query: 241 DWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDG 300
           DWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDG
Sbjct: 241 DWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDG 300

Query: 301 DIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVR 360
           DIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVR
Sbjct: 301 DIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVR 360

Query: 361 GEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEM 420
           GEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEM
Sbjct: 361 GEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEM 420

Query: 421 NTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVW 480
           NTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVW
Sbjct: 421 NTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVW 480

Query: 481 RPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEE 540
           RPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEE
Sbjct: 481 RPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEE 540

Query: 541 VMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSCLFCKRAVCTSCS 600
           VMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSCLFCKRAVCTSCS
Sbjct: 541 VMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSCLFCKRAVCTSCS 600

Query: 601 IKMKMPSKKFGHIPVYTLGFESPQRVSAAKTAPIQRRDIFQSLQGPQWQSVEEAFPHIYS 660
           IKMKMPSKKFGHIPVYTLGFESPQRVSAAKTAPIQRRDIFQSLQGPQWQSVEEAFPHIYS
Sbjct: 601 IKMKMPSKKFGHIPVYTLGFESPQRVSAAKTAPIQRRDIFQSLQGPQWQSVEEAFPHIYS 660

Query: 661 HGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK 714
           HGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK
Sbjct: 661 HGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK 714


>gi|191250771 spire homolog 1 isoform b [Homo sapiens]
          Length = 742

 Score =  508 bits (1309), Expect = e-144
 Identities = 312/738 (42%), Positives = 428/738 (57%), Gaps = 77/738 (10%)

Query: 5   GSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGS-----PGRRL 59
           G+ GGAA G+       LSLEE+L+ Y QP+NEEQAWAVC+Q C  LR +     P  R+
Sbjct: 27  GAAGGAAGGSRDA----LSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRV 82

Query: 60  RDTGDLLLRGDGSV--GAREPEAAEPATMVVPLASS---EAQTVQSLGFAIYRALDWGLD 114
           R    + +  DG+V       +A EP  +   L  S   E + ++SLG  IY+ALD+GL 
Sbjct: 83  RSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLK 142

Query: 115 ESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQ 170
           E+EERELSP LE+LID MAN    + S D G  AA+EG G  +E+ +      ++R++  
Sbjct: 143 ENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKIS----AIRSYRD 198

Query: 171 AMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETP 230
            M+LCAA L     A  HYQAVCRALF ET+EL  FL +++ AKE L+K++E E   E+ 
Sbjct: 199 VMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESS 258

Query: 231 RAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARN 290
             +L+ L + DWAR WVQ+MR+LR GVKLKKVQE+++NPLP E+QLTP+EMLM DIR + 
Sbjct: 259 -TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKR 317

Query: 291 YKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEI 350
           Y LRKVMV+GDIPPR+KK AHE+ILDFIRSRPPL  VS R+L+P PP+ RSLHE+ILEEI
Sbjct: 318 YTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEI 377

Query: 351 KQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINLSVT----DAGGSAQRPRP- 405
           K ER+LRPV  E         L       + +   +S +N  +T    + G S  +  P 
Sbjct: 378 KAERKLRPVSPEEIRR---SRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPA 434

Query: 406 --RVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHP 463
             + LL+APTLAE++   + EE        TL +  S S    +     V   + +   P
Sbjct: 435 QRKKLLRAPTLAELDSSESEEE--------TLHKSTSSSSVSPSFPEEPVLEAVSTRKKP 486

Query: 464 P-----GGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTP 518
           P       T  P  R       +P  R       + ++    L  +R SS          
Sbjct: 487 PKFLPISSTPQPERR-------QPPQRRHSIEKETPTNVRQFLPPSRQSSRSLE------ 533

Query: 519 DAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRA- 577
                  EF +PVE LALTVEEVM +R+VLVKAE+EK+ Q K+++++LKKGK+C CCR  
Sbjct: 534 -------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 586

Query: 578 KFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQR---------VSA 628
           +F  F+W  +C FCKR VC+ C  KM++PSK +  +P+++LG  + QR          S 
Sbjct: 587 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 646

Query: 629 AKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSV 687
           A   P++    F S      +S EE  FP          +VC +C  F+++++ SSR+S+
Sbjct: 647 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 706

Query: 688 DVLNTTPRRSRQTQSLYI 705
            + N   R  R+TQS Y+
Sbjct: 707 VLANKRARLKRKTQSFYM 724


>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
          Length = 756

 Score =  507 bits (1305), Expect = e-143
 Identities = 310/749 (41%), Positives = 429/749 (57%), Gaps = 85/749 (11%)

Query: 5   GSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGS-----PGRRL 59
           G+ GGAA G+       LSLEE+L+ Y QP+NEEQAWAVC+Q C  LR +     P  R+
Sbjct: 27  GAAGGAAGGSRDA----LSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRV 82

Query: 60  RDTGDLLLRGDGSV--GAREPEAAEPATMVVPLASS---EAQTVQSLGFAIYRALDWGLD 114
           R    + +  DG+V       +A EP  +   L  S   E + ++SLG  IY+ALD+GL 
Sbjct: 83  RSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLK 142

Query: 115 ESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQ 170
           E+EERELSP LE+LID MAN    + S D G  AA+EG G  +E+ +      ++R++  
Sbjct: 143 ENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKIS----AIRSYRD 198

Query: 171 AMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETP 230
            M+LCAA L     A  HYQAVCRALF ET+EL  FL +++ AKE L+K++E E   E+ 
Sbjct: 199 VMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESS 258

Query: 231 RAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARN 290
             +L+ L + DWAR WVQ+MR+LR GVKLKKVQE+++NPLP E+QLTP+EMLM DIR + 
Sbjct: 259 -TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKR 317

Query: 291 YKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEI 350
           Y LRKVMV+GDIPPR+KK AHE+ILDFIRSRPPL  VS R+L+P PP+ RSLHE+ILEEI
Sbjct: 318 YTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEI 377

Query: 351 KQERRLRPVRGEGWAARGFGSLPCI------LNACSGDAKSTSCINLSVTDAGGSAQR-- 402
           K ER+LRPV  E          P        L+  +    + + +  S+ + G ++Q   
Sbjct: 378 KAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKE 437

Query: 403 ----------PRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSE 452
                      + + LL+APTLAE++   + EE        TL +  S S    +     
Sbjct: 438 NGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--------TLHKSTSSSSVSPSFPEEP 489

Query: 453 VASGLQSATHPP-----GGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGS 507
           V   + +   PP       T  P  R       +P  R       + ++    L  +R S
Sbjct: 490 VLEAVSTRKKPPKFLPISSTPQPERR-------QPPQRRHSIEKETPTNVRQFLPPSRQS 542

Query: 508 SGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLK 567
           S                 EF +PVE LALTVEEVM +R+VLVKAE+EK+ Q K+++++LK
Sbjct: 543 SRSLE-------------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALK 589

Query: 568 KGKICCCCRA-KFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQR- 625
           KGK+C CCR  +F  F+W  +C FCKR VC+ C  KM++PSK +  +P+++LG  + QR 
Sbjct: 590 KGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRG 649

Query: 626 --------VSAAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLKDVCSECTSFV 676
                    S A   P++    F S      +S EE  FP          +VC +C  F+
Sbjct: 650 ESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFI 709

Query: 677 ADVVRSSRKSVDVLNTTPRRSRQTQSLYI 705
           ++++ SSR+S+ + N   R  R+TQS Y+
Sbjct: 710 SEIISSSRRSLVLANKRARLKRKTQSFYM 738


>gi|191250775 spire homolog 1 isoform c [Homo sapiens]
          Length = 622

 Score =  454 bits (1168), Expect = e-127
 Identities = 273/639 (42%), Positives = 376/639 (58%), Gaps = 63/639 (9%)

Query: 94  EAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGY 149
           E + ++SLG  IY+ALD+GL E+EERELSP LE+LID MAN    + S D G  AA+EG 
Sbjct: 2   ETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGL 61

Query: 150 GGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLAR 209
           G  +E+ +      ++R++   M+LCAA L     A  HYQAVCRALF ET+EL  FL +
Sbjct: 62  GDEDEKRKIS----AIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTK 117

Query: 210 VREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNP 269
           ++ AKE L+K++E E   E+   +L+ L + DWAR WVQ+MR+LR GVKLKKVQE+++NP
Sbjct: 118 IKSAKENLKKIQEMEKSDESS-TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNP 176

Query: 270 LPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSE 329
           LP E+QLTP+EMLM DIR + Y LRKVMV+GDIPPR+KK AHE+ILDFIRSRPPL  VS 
Sbjct: 177 LPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSA 236

Query: 330 RRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCI 389
           R+L+P PP+ RSLHE+ILEEIK ER+LRPV  E         L       + +   +S +
Sbjct: 237 RKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRR---SRLDVTTPESTKNLVESSMV 293

Query: 390 NLSVT----DAGGSAQRPRP---RVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFS 442
           N  +T    + G S  +  P   + LL+APTLAE++   + EE        TL +  S S
Sbjct: 294 NGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--------TLHKSTSSS 345

Query: 443 EHDLAQLRSEVASGLQSATHPP-----GGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDP 497
               +     V   + +   PP       T  P  R       +P  R       + ++ 
Sbjct: 346 SVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERR-------QPPQRRHSIEKETPTNV 398

Query: 498 SHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFL 557
              L  +R SS                 EF +PVE LALTVEEVM +R+VLVKAE+EK+ 
Sbjct: 399 RQFLPPSRQSSRSLE-------------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQ 445

Query: 558 QNKELFSSLKKGKICCCCRA-KFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVY 616
           Q K+++++LKKGK+C CCR  +F  F+W  +C FCKR VC+ C  KM++PSK +  +P++
Sbjct: 446 QYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIF 505

Query: 617 TLGFESPQR---------VSAAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLK 666
           +LG  + QR          S A   P++    F S      +S EE  FP          
Sbjct: 506 SLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTM 565

Query: 667 DVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYI 705
           +VC +C  F+++++ SSR+S+ + N   R  R+TQS Y+
Sbjct: 566 EVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYM 604


>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 84/403 (20%), Positives = 148/403 (36%), Gaps = 48/403 (11%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELD---SLGHTDWARLWVQLMRELRRGVK 258
           L+A L +++E+ + LQ  R++   H+E  RA      S    +   L  +  +++RR  +
Sbjct: 212 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEE 271

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + H  +
Sbjct: 272 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQHISL 326

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  R +    +  E RLR    + +  HEK+ +  K +     +  E  +         
Sbjct: 327 LN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVK 384

Query: 375 ILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVT 434
            L    G+ K T        +A      P P          E        +E++   E+ 
Sbjct: 385 ELQEKLGEVKETETSAQKEPEAARGPGAPGPG--------GESSSFMDHLKEKADLSELV 436

Query: 435 LKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASV 494
            K++  F ++   +   ++   L      PGG        G  H       D+G    + 
Sbjct: 437 KKQELRFIQYWQERCHQKIHHLLSE----PGGRAKDAALGGGHHQAGAQGGDEGEAAGAA 492

Query: 495 SD----------PSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSH-PVESLALTVEEVMD 543
           +D               L+   +S D P     P  + L     H  +  + LT     +
Sbjct: 493 ADGIAAYSNYNNGHRKFLAAAHNSADEPGPG-APAPQELGAADKHGDLREVTLTSSAQGE 551

Query: 544 VRR--VLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSW 584
            R   +L K   +  +Q+ +    L  G  CC      PLF W
Sbjct: 552 AREDPLLDKPTAQPIVQDHQEHPGL--GSNCC-----VPLFCW 587


>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 84/403 (20%), Positives = 148/403 (36%), Gaps = 48/403 (11%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELD---SLGHTDWARLWVQLMRELRRGVK 258
           L+A L +++E+ + LQ  R++   H+E  RA      S    +   L  +  +++RR  +
Sbjct: 212 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEE 271

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + H  +
Sbjct: 272 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQHISL 326

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  R +    +  E RLR    + +  HEK+ +  K +     +  E  +         
Sbjct: 327 LN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVK 384

Query: 375 ILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVT 434
            L    G+ K T        +A      P P          E        +E++   E+ 
Sbjct: 385 ELQEKLGEVKETETSAQKEPEAARGPGAPGPG--------GESSSFMDHLKEKADLSELV 436

Query: 435 LKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASV 494
            K++  F ++   +   ++   L      PGG        G  H       D+G    + 
Sbjct: 437 KKQELRFIQYWQERCHQKIHHLLSE----PGGRAKDAALGGGHHQAGAQGGDEGEAAGAA 492

Query: 495 SD----------PSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSH-PVESLALTVEEVMD 543
           +D               L+   +S D P     P  + L     H  +  + LT     +
Sbjct: 493 ADGIAAYSNYNNGHRKFLAAAHNSADEPGPG-APAPQELGAADKHGDLREVTLTSSAQGE 551

Query: 544 VRR--VLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSW 584
            R   +L K   +  +Q+ +    L  G  CC      PLF W
Sbjct: 552 AREDPLLDKPTAQPIVQDHQEHPGL--GSNCC-----VPLFCW 587


>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 595

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 103/499 (20%), Positives = 183/499 (36%), Gaps = 57/499 (11%)

Query: 115 ESEERELSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMR- 173
           +  EREL  Q++ LI +     + D         Y   E ++ A  +  S++   +  R 
Sbjct: 117 QKAERELEVQIQTLI-IQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELERA 175

Query: 174 LCAARLTDPRGA-------QAHYQAVCRALFVETLELRAFLARVREAKEMLQKLRED-EP 225
           L A   T+ + A       +AH +        +   L+A L +++E+ + LQ  R++   
Sbjct: 176 LSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAE 235

Query: 226 HLETPRAELD---SLGHTDWARLWVQLMRELRRGVKLK----KVQEQEFNPLPTEFQLTP 278
           H+E  RA      S    +   L  +  +++RR  +L+    K++ Q   PLP E    P
Sbjct: 236 HIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP 295

Query: 279 FEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPK 338
            E+ +Q +R    +     V G++  +VK + H  +L+  R +    +  E RLR    +
Sbjct: 296 SEVELQHLRKELER-----VAGELQSQVKNNQHISLLN--RRQEERIREQEERLRKQEER 348

Query: 339 QRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGG 398
            +  HEK+ +  K +     +  E  +          L    G+ K T        +A  
Sbjct: 349 LQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEPEAAR 408

Query: 399 SAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQ 458
               P P          E        +E++   E+  K++  F ++   +   ++   L 
Sbjct: 409 GPGAPGPG--------GESSSFMDHLKEKADLSELVKKQELRFIQYWQERCHQKIHHLLS 460

Query: 459 SATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSD----------PSHPLLSNRGSS 508
                PGG        G  H       D+G    + +D               L+   +S
Sbjct: 461 E----PGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNS 516

Query: 509 GDRPEASMTPDAKHLWLEFSH-PVESLALTVEEVMDVRR--VLVKAEMEKFLQNKELFSS 565
            D P     P  + L     H  +  + LT     + R   +L K   +  +Q+ +    
Sbjct: 517 ADEPGPG-APAPQELGAADKHGDLREVTLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPG 575

Query: 566 LKKGKICCCCRAKFPLFSW 584
           L  G  CC      PLF W
Sbjct: 576 L--GSNCC-----VPLFCW 587


>gi|169208016 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a, 8E isoform 1 [Homo sapiens]
          Length = 594

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 84/407 (20%), Positives = 145/407 (35%), Gaps = 57/407 (14%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRA-----------ELDSLGHTDWARLWVQLM 250
           L+A L +++E+ + LQ  R++   H+E  RA           E+ +L        WV+ +
Sbjct: 212 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQDMRWVEQL 271

Query: 251 RELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDA 310
                   L K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + 
Sbjct: 272 EW-----SLSKLKNQTAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQ 321

Query: 311 HELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFG 370
           H  +L+  R +    +  E RLR    + +  HEK+ +  K +     +  E  +     
Sbjct: 322 HISLLN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLE 379

Query: 371 SLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPC 430
                L    G+ K T        +A      P P          E        +E++  
Sbjct: 380 QQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG--------GESSSFMDHLKEKADL 431

Query: 431 GEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTC 490
            E+  K++  F ++   +   ++   L      PGG        G  H       D+G  
Sbjct: 432 SELLKKQELRFIQYWQERCHQKIHHLLSE----PGGRAKDAALGGGHHQAGAQGGDEGEA 487

Query: 491 PASVSD----------PSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSH-PVESLALTVE 539
             + +D               L+   +S D P     P  + L     H  +  + LT  
Sbjct: 488 AGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPG-APAPQELGAADKHGDLREVTLTSS 546

Query: 540 EVMDVRR--VLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSW 584
              + R   +L K   +  +Q+ +    L  G  CC      PLF W
Sbjct: 547 AQGEAREDPLLDKPTAQPIVQDHQEHPGL--GSNCC-----VPLFCW 586


>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 88/424 (20%), Positives = 155/424 (36%), Gaps = 61/424 (14%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELD---SLGHTDWARLWVQLMRELRRGVK 258
           L+A L +++E+ + LQ  R++   H+E  RA      S    +   L  +  +++RR  +
Sbjct: 220 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEE 279

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + H  +
Sbjct: 280 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQHISL 334

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  R +    +  E RLR    + +  HEK+ +  K +     +  E  +         
Sbjct: 335 LN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVK 392

Query: 375 ILNACSGD--AKSTSCINLSVT-------------------DAGGSAQRPRPRVLLKAPT 413
            L    G+   ++ S  N  +T                     G  A RP P V     +
Sbjct: 393 ELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDPES 452

Query: 414 LAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPR 473
              M       +E++   E+  K++  F ++   +   ++   L      PGG       
Sbjct: 453 REAMSSFMDHLKEKADLSELVKKQELRFIQYWQERCHQKIHHLLSE----PGGRAKDAAL 508

Query: 474 AGSAHVWRPGSRDQGTCPASVSD----------PSHPLLSNRGSSGDRPEASMTPDAKHL 523
            G  H       D+G    + +D               L+   +S D P     P  + L
Sbjct: 509 GGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPG-APAPQEL 567

Query: 524 WLEFSH-PVESLALTVEEVMDVRR--VLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFP 580
                H  +  + LT     + R   +L K   +  +Q+ +    L  G  CC      P
Sbjct: 568 GAADKHGDLREVTLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGL--GSNCC-----VP 620

Query: 581 LFSW 584
           LF W
Sbjct: 621 LFCW 624


>gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo
           sapiens]
          Length = 1052

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 87/448 (19%), Positives = 155/448 (34%), Gaps = 88/448 (19%)

Query: 109 LDWGLDESEE-----RELSPQLERLI--DLMANNDSEDSGCGAADEGYGGPEEEEEAEG- 160
           L WG+ ++ E     REL  Q++RL       N D  D+ C          EE ++  G 
Sbjct: 154 LSWGIGKANEKQKAKRELEVQIQRLNIQKKXLNTDLYDTKCSLRYF-----EESKDLAGC 208

Query: 161 VPRSVRTFAQAMRLCAARLTDPRG-------AQAHYQAVCRALFVETLELRAFLARVREA 213
           +  S++   +  R  +A  T           ++AH +        E   L+A L +++E+
Sbjct: 209 LQYSLQCIGELERALSAVTTTEEKEISFSSRSRAHTEWELEQSLQEKARLKAXLTQLKES 268

Query: 214 KEMLQKLRED-EPHLETPRAELDSLGHTDWARLWVQLMRELRRGV--------------- 257
            + +Q  R++    ++  RA             W Q MR++ + V               
Sbjct: 269 FQQVQLQRDNYAQQIKGERAR------------WQQRMRKMSQEVYTLKTEKEHYTHRVE 316

Query: 258 ----KLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHEL 313
                L K++ Q   PLP E    P E+  Q +R    +     V G++  +VK +    
Sbjct: 317 GLERSLSKLKNQMAEPLPPEPPAVPSEVEPQHLRKELDR-----VAGELQVQVKNNQRIS 371

Query: 314 ILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLP 373
           +L++ +     +Q  E RLR    +    H+++ +  + +   + +  E  +A       
Sbjct: 372 LLNWGQDERIREQ--EERLRKQEERFXEQHKRLQQLAEPQSIFKELNNENKSALQLEQQV 429

Query: 374 CILNACSGDAKSTSCINLS-------------------------VTDAGGSAQRPRPRVL 408
             L    G+ K T  +  +                         +   G  A RP P V 
Sbjct: 430 KELQEKLGEVKDTEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSDGEEAPRPMPSVP 489

Query: 409 LKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTE 468
               +   M       EE++   E+  K++  F  H     R      +      PGG  
Sbjct: 490 EDLESREAMSSFMDQLEEKADLSELVKKKELCFIHH----WRDRCHQKIHHLLSEPGGRA 545

Query: 469 PPRPRAGSAHVWRPGSRDQGTCPASVSD 496
                 G  H       D+G    + +D
Sbjct: 546 KDAALVGGHHQAGAQGGDEGEAAGAAAD 573


>gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo
           sapiens]
          Length = 1102

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 84/424 (19%), Positives = 148/424 (34%), Gaps = 72/424 (16%)

Query: 109 LDWGLDESEE-----RELSPQLERLI--DLMANNDSEDSGCGAADEGYGGPEEEEEAEG- 160
           L WG+ ++ E     REL  Q++RL       N D  D+ C          EE ++  G 
Sbjct: 236 LSWGIGKANEKQKAKRELEVQIQRLNIQKKXLNTDLYDTKCSLRYF-----EESKDLAGC 290

Query: 161 VPRSVRTFAQAMRLCAARLTDPRG--------AQAHYQAVCRALFVETLELRAFLARVRE 212
           +  S++   +  R  +A  T            ++AH +        E   L+A L R++E
Sbjct: 291 LQYSLQCIGELERALSAVTTTEEKEISGFSSRSRAHTEWELEQSLQEKARLKAXLTRLKE 350

Query: 213 AKEMLQKLRED-EPHLETPRAELDSLGHTDWARLWVQLMRELRRGV-------------- 257
           + + +Q  R++    ++  RA             W Q MR++ + V              
Sbjct: 351 SFQQVQLQRDNYAQQIKGERAR------------WQQRMRKMSQEVYTLKTEKEHYTHRV 398

Query: 258 -----KLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHE 312
                 L K++ Q   PLP E    P E+  Q +R    +     V G++  +VK +   
Sbjct: 399 EGLERSLSKLKNQMAEPLPPEPPAVPSEVEPQHLRKELDR-----VAGELQVQVKNNQRI 453

Query: 313 LILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSL 372
            +L++ +     +Q  E RLR    +    H+++ +  + +   + +  E  +A      
Sbjct: 454 SLLNWGQDERIREQ--EERLRKQEERLXEQHKRLQQLAEPQSIFKELNNENKSALQLEQQ 511

Query: 373 PCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGE 432
              L    G+ K          +A      P P          E        EE++   E
Sbjct: 512 VKELQEKLGEVKDPVASAQKEPEAARGPGAPGPG--------GESSSFMDHLEEKADLSE 563

Query: 433 VTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPA 492
           +  K++  F  H     R      +      PGG        G  H       D+G    
Sbjct: 564 LVKKKELCFIHH----WRDRCHQKIHHLLSEPGGRAKDAALVGGHHQAGAQGGDEGEAAG 619

Query: 493 SVSD 496
           + +D
Sbjct: 620 AAAD 623


>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 15/168 (8%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELD---SLGHTDWARLWVQLMRELRRGVK 258
           L+A L +++E+ + LQ  R++   H+E  RA      S    +   L  +  +++RR  +
Sbjct: 220 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEE 279

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + H  +
Sbjct: 280 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQHISL 334

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGE 362
           L+  R +    +  E RLR    + +  HEK+ +  K +     +  E
Sbjct: 335 LN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNE 380


>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 4 [Homo sapiens]
          Length = 632

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 106/520 (20%), Positives = 191/520 (36%), Gaps = 70/520 (13%)

Query: 115 ESEERELSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMR- 173
           +  EREL  Q++ LI +     + D         Y   E ++ A  +  S++   +  R 
Sbjct: 125 QKAERELEVQIQTLI-IQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELERA 183

Query: 174 LCAARLTDPRGA-------QAHYQAVCRALFVETLELRAFLARVREAKEMLQKLRED-EP 225
           L A   T+ + A       +AH +        +   L+A L +++E+ + LQ  R++   
Sbjct: 184 LSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAE 243

Query: 226 HLETPRAELD---SLGHTDWARLWVQLMRELRRGVKLK----KVQEQEFNPLPTEFQLTP 278
           H+E  RA      S    +   L  +  +++RR  +L+    K++ Q   PLP E    P
Sbjct: 244 HIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP 303

Query: 279 FEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPK 338
            E+ +Q +R    +     V G++  +VK + H  +L+  R +    +  E RLR    +
Sbjct: 304 SEVELQHLRKELER-----VAGELQSQVKNNQHISLLN--RRQEERIREQEERLRKQEER 356

Query: 339 QRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILN----------ACSGDAKSTSC 388
            +  HEK+ +  K +     +  E  +          L           A   + + T+ 
Sbjct: 357 LQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQLTAQ 416

Query: 389 INL-----------SVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKR 437
           +NL            +   G  A +P P V     +   M       +E++   E+  K+
Sbjct: 417 LNLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLKEKADLSELVKKQ 476

Query: 438 DRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSD- 496
           +  F ++   +   ++   L      PGG        G  H       D+G    + +D 
Sbjct: 477 ELRFIQYWQERCHQKIHHLLSE----PGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADG 532

Query: 497 ---------PSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSH-PVESLALTVEEVMDVRR 546
                         L+   +S D P     P  + L     H  +  + LT     + R 
Sbjct: 533 IAAYSNYNNGHRKFLAAAHNSADEPGPG-APAPQELGAADKHGDLREVTLTSSAQGEARE 591

Query: 547 --VLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSW 584
             +L K   +  +Q+ +    L  G  CC      PLF W
Sbjct: 592 DPLLDKPTAQPIVQDHQEHPGL--GSNCC-----VPLFCW 624


>gi|113425119 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a, 8E isoform 2 [Homo sapiens]
          Length = 631

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 24/172 (13%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRA-----------ELDSLGHTDWARLWVQLM 250
           L+A L +++E+ + LQ  R++   H+E  RA           E+ +L        WV+ +
Sbjct: 220 LKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQDMRWVEQL 279

Query: 251 RELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDA 310
                   L K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK + 
Sbjct: 280 EW-----SLSKLKNQTAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQSQVKNNQ 329

Query: 311 HELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGE 362
           H  +L+  R +    +  E RLR    + +  HEK+ +  K +     +  E
Sbjct: 330 HISLLN--RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNE 379


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 11/134 (8%)

Query: 17  PEPWE-LSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLRDT-----GDLLLRGD 70
           PE  E +SL ++L   ++ L+E++AWAVC +    +R      +  +       L     
Sbjct: 31  PEDEENVSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNTS 90

Query: 71  GSVGAREPEAAEPATMVVP-----LASSEAQTVQSLGFAIYRALDWGLDESEERELSPQL 125
           G+V   E  + +P    VP       ++    + SLG  +  AL++  + + E  LS  L
Sbjct: 91  GNVCFMEQLSDDPEGAFVPPEFDVTGNTFEAHIYSLGATLKAALEYVAEPTLEPRLSQDL 150

Query: 126 ERLIDLMANNDSED 139
           E L+  M   D  D
Sbjct: 151 EALLSRMQAEDPGD 164


>gi|239750798 PREDICTED: similar to hect domain and RLD 2 [Homo
           sapiens]
          Length = 691

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 81/413 (19%), Positives = 144/413 (34%), Gaps = 67/413 (16%)

Query: 115 ESEERELSPQLERLI--DLMANNDSEDSGCGAADEGYGGPEEEEEAEG-VPRSVRTFAQA 171
           +  +REL  Q++RL       N D  D+ C          EE ++  G +  S++   + 
Sbjct: 237 QKAKRELEVQIQRLNIQKKXLNTDLYDTKCSLRYF-----EESKDLAGCLQYSLQCIGEL 291

Query: 172 MRLCAARLTDPRG--------AQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLRED 223
            R  +A  T            ++AH +        E   L+A L R++E+ + +Q  R++
Sbjct: 292 ERALSAVTTTEEKEISGFSSRSRAHTEWELEQSLQEKARLKAXLTRLKESFQQVQLQRDN 351

Query: 224 -EPHLETPRAELDSLGHTDWARLWVQLMRELRRGV-------------------KLKKVQ 263
               ++  RA             W Q MR++ + V                    L K++
Sbjct: 352 YAQQIKGERAR------------WQQRMRKMSQEVYTLKTEKEHYTHRVEGLERSLSKLK 399

Query: 264 EQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPP 323
            Q   PLP E    P E+  Q +R    +     V G++  +VK +    +L++ +    
Sbjct: 400 NQMAEPLPPEPPAVPSEVEPQHLRKELDR-----VAGELQVQVKNNQRISLLNWGQDERI 454

Query: 324 LKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDA 383
            +Q  E RLR    +    H+++ +  + +   + +  E  +A         L    G+ 
Sbjct: 455 REQ--EERLRKQEERLXEQHKRLQQLAEPQSIFKELNNENKSALQLEQQVKELQEKLGEV 512

Query: 384 KSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSE 443
           K T        +A      P P          E        EE++   E+  K++  F  
Sbjct: 513 KDTETSAQKEPEAARGPGAPGPG--------GESSSFMDHLEEKADLSELVKKKELCFIH 564

Query: 444 HDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSD 496
           H     R      +      PGG        G  H       D+G    + +D
Sbjct: 565 H----WRDRCHQKIHHLLSEPGGRAKDAALVGGHHQAGAQGGDEGEAAGAAAD 613


>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
          Length = 621

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 46/171 (26%), Positives = 56/171 (32%), Gaps = 18/171 (10%)

Query: 381 GDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTL--AEMEEMNTSEEEESPCGEVTLKRD 438
           GDA+  SC         GS + PR  + L    L  AE        E E P G V  +  
Sbjct: 392 GDAEGASCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREPEEPEGAVAARAA 451

Query: 439 RSFSEH-----DLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCP-A 492
           R            A LR    SGL     PP    PP           PGS D  + P A
Sbjct: 452 RGQGGRLPRTGRYAALRRRSTSGLPDYRAPPSPEPPP----------SPGSADPDSSPLA 501

Query: 493 SVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMD 543
             + PS PL         R   S   D      +   P+     + E V+D
Sbjct: 502 KAASPSPPLRLEGSPPTRRDSGSSQSDDPSSSNKGYTPLREAGTSTESVLD 552


>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 [Homo sapiens]
          Length = 602

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 62/302 (20%), Positives = 108/302 (35%), Gaps = 27/302 (8%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L +++E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 219 LKVQLTQLKESFQQVQLERDECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 278

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VKK+    +
Sbjct: 279 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKKNQRISL 333

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  + +    Q  E RLR    + +  H+ + +  K +        E   A        
Sbjct: 334 LN--QRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVK 391

Query: 375 ILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVT 434
            L    G+ K T        +A      P P          E        EE++   E+ 
Sbjct: 392 ELQEKLGEVKETETSAQKEPEAARGPGAPGPG--------GESSSFMDHLEEKADLSELV 443

Query: 435 LKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASV 494
            K++  F  H     R             PGG        G  H       D+G    + 
Sbjct: 444 KKKELCFIHH----WRDRCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAA 499

Query: 495 SD 496
           +D
Sbjct: 500 AD 501


>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 384

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 17/147 (11%)

Query: 393 VTDAGGSAQRPRPRVLLKAP------TLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDL 446
           V+D  G A R  PR   + P      +L+    +  +  E SP           F    L
Sbjct: 60  VSDRAGPATRAEPRTASEQPRPHAPGSLSRRRALGCAHAERSPGVLGVAFHPMVFHCGLL 119

Query: 447 AQLRSEV-ASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNR 505
           A +R  + ASG  +A  PP    PPR + G       GSR  G+  AS+     P  +  
Sbjct: 120 AVMRQRISASGRGTAAAPPW---PPRRKCG-------GSRGVGSSSASLLPTPAPKAAAL 169

Query: 506 GSSGDRPEASMTPDAKHLWLEFSHPVE 532
              G R   S+  +AK +  E S+  E
Sbjct: 170 DGLGSRKVKSLCKEAKEILTEESNAQE 196


>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
           [Homo sapiens]
          Length = 580

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 72/356 (20%), Positives = 127/356 (35%), Gaps = 52/356 (14%)

Query: 163 RSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLR- 221
           RS+R F +  +  A RL      +   ++V   +     +      +  + KE  Q+++ 
Sbjct: 154 RSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKK------KANQFKESFQQVQL 207

Query: 222 ---EDEPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVKLK----KVQEQEFNPLP 271
              E   HL+  RA           +   L  +  +++RR  KL+    K++ Q   PLP
Sbjct: 208 ERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLP 267

Query: 272 TEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERR 331
            E    P E+ +Q +R    +     V G++  +VK +    +L+         Q  E R
Sbjct: 268 PEPPAVPSEVELQHLRKELER-----VAGELQAQVKNNQRISLLN---------QRQEER 313

Query: 332 LRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINL 391
           +R    + R   E+I E+ K  ++L   +        F     +  A   + + T+ ++L
Sbjct: 314 IREQEERLRKQEERIQEQHKSLQQLAKPQSV------FKEPEHLEAASQQNQQLTAQLSL 367

Query: 392 -----------SVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRS 440
                       +   G  A RP P V     +   M       EE++   E+  K++  
Sbjct: 368 MALPGEGHGGEHLDSEGEEAPRPMPSVPEDPESREAMSSFMDHLEEKADLSELVKKKELC 427

Query: 441 FSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSD 496
           F  H     R             PGG        G  H       D+G    + +D
Sbjct: 428 FIHH----WRERCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAAAD 479


>gi|169171485 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 349

 Score = 37.0 bits (84), Expect = 0.064
 Identities = 49/168 (29%), Positives = 62/168 (36%), Gaps = 20/168 (11%)

Query: 35  LNEEQAWAVCFQGCRGLRGSPGRRLRDTGDLLLRGDGSVGAREPE------AAEPA---T 85
           L   QAW+    GCR L  +P R  R    L  R    VG   PE      AA PA   T
Sbjct: 131 LRGPQAWSAIRTGCRALEWAPHRGSRRWARLGFRVPSGVGWGGPERPKALKAAWPAPLST 190

Query: 86  MVVPLASSEAQTVQSLGFAIYRALD-WGLDESEERELSPQLERLIDLMANNDSEDSGCGA 144
              P   S AQ V     A+ R L+       + R    + +RL  L   + + +  C  
Sbjct: 191 AKAPAGLSAAQQVT----ALQRLLELHSAARRQRRRRDREQQRLRVLERLHIARNRHCRV 246

Query: 145 ADEGYGG-----PEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQA 187
              G        P +    EGV R      +  R C AR T+PR   A
Sbjct: 247 HPVGLPASPAQLPPQARPLEGVTRR-GARGRCARCCPARPTEPRTLSA 293


>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 2 [Homo sapiens]
          Length = 602

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 61/302 (20%), Positives = 108/302 (35%), Gaps = 27/302 (8%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L + +E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 219 LKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 278

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK +    +
Sbjct: 279 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKNNQRISL 333

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  R    +++  E RLR    + +  H+ + +  K +   +    E   A        
Sbjct: 334 LN-QRQEERIRE-QEERLRKQEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLEQQVK 391

Query: 375 ILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVT 434
            L    G+ K T        +A      P P          E        EE++   E+ 
Sbjct: 392 ELQEKLGEVKETETSAQKEPEAARGPGAPGPG--------GESSSFMDHLEEKADLSELV 443

Query: 435 LKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASV 494
            K++  F  H     R             PGG        G  H       D+G    + 
Sbjct: 444 KKKELCFIHH----WRERCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAA 499

Query: 495 SD 496
           +D
Sbjct: 500 AD 501


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 44/164 (26%), Positives = 66/164 (40%), Gaps = 21/164 (12%)

Query: 380 SGDAKSTSCINLSVTDAGGSA-QRPRPRVLLKAP-TLAEMEEMNTSEEEESPCGEVTLKR 437
           +G++K  + IN +  DA  +A +    + L   P T++   + ++  E      E  L  
Sbjct: 138 TGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAA 197

Query: 438 DRSFSEHDLA-QLRSE----------VASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRD 486
               S+ D   QL ++          V S L S   PPG    P P +    V  PG+  
Sbjct: 198 QNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPG---MPPPGSFPPPVPPPGALP 254

Query: 487 QGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHP 530
            G  PA    P  P     G++G  P ++ TP A H     SHP
Sbjct: 255 PGIPPAMPPPPMPP-----GAAGHGPPSAGTPGAGHPGHGHSHP 293


>gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 601

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 22/162 (13%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L +++E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 219 LKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 278

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VKK+    +
Sbjct: 279 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKKNQRISL 333

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRL 356
           L+         Q  E R++    + R   E+I E+ K  ++L
Sbjct: 334 LN---------QRQEERIQEQEERLRKQEERIQEQHKSLQQL 366


>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 630

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 22/162 (13%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L +++E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 220 LKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 279

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VKK+    +
Sbjct: 280 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKKNQRISL 334

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRL 356
           L+         Q  E R++    + R   E+I E+ K  ++L
Sbjct: 335 LN---------QRQEERIQEQEERLRKQEERIQEQHKSLQQL 367


>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 66/323 (20%), Positives = 115/323 (35%), Gaps = 40/323 (12%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L +++E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 220 LKVQLTQLKESFQQVQLERDECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 279

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VKK+    +
Sbjct: 280 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKKNQRISL 334

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPC 374
           L+  + +    Q  E RLR    + +  H+ + +  K +        E   A        
Sbjct: 335 LN--QRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVK 392

Query: 375 ILNACSGD--AKSTSCINLSVT-------------------DAGGSAQRPRPRVLLKAPT 413
            L    G+   ++ S  N  +T                     G  A RP P V     +
Sbjct: 393 ELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDPES 452

Query: 414 LAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPR 473
              M       EE++   E+  K++  F  H     R             PGG       
Sbjct: 453 REAMSSFMDHLEEKADLSELVKKKELCFIHH----WRDRCHQKTHHLLSEPGGRAKDAAL 508

Query: 474 AGSAHVWRPGSRDQGTCPASVSD 496
            G  H       D+G    + +D
Sbjct: 509 GGGHHQAGAQGGDEGEAAGAAAD 531


>gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 45/158 (28%), Positives = 68/158 (43%), Gaps = 19/158 (12%)

Query: 395 DAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLR---- 450
           D   SA   +P +L  + TL+  +  +   + ES      +K  +S    +L Q+     
Sbjct: 325 DISSSANTQKPALL--SSTLSSGKARSKKCKHESGDSSGCIKPPKSPLSPELIQVEDLTL 382

Query: 451 -SEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPA---SVSDPSHPLLSNRG 506
            S+++S + + T PP    PPRP   S    R  S+   T P    SV   S P  +  G
Sbjct: 383 VSQLSSSVINKTSPPQPVNPPRPFKHSER--RRRSQRLATLPMPDDSVEKVSSPSPATDG 440

Query: 507 -----SSGDRPEASM--TPDAKHLWLEFSHPVESLALT 537
                SS ++ E+S+   PD  HL LE   P   L L+
Sbjct: 441 KVFSISSQNQQESSVPEVPDVAHLPLEKLGPCLPLDLS 478


>gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 45/158 (28%), Positives = 68/158 (43%), Gaps = 19/158 (12%)

Query: 395 DAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLR---- 450
           D   SA   +P +L  + TL+  +  +   + ES      +K  +S    +L Q+     
Sbjct: 325 DISSSANTQKPALL--SSTLSSGKARSKKCKHESGDSSGCIKPPKSPLSPELIQVEDLTL 382

Query: 451 -SEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPA---SVSDPSHPLLSNRG 506
            S+++S + + T PP    PPRP   S    R  S+   T P    SV   S P  +  G
Sbjct: 383 VSQLSSSVINKTSPPQPVNPPRPFKHSER--RRRSQRLATLPMPDDSVEKVSSPSPATDG 440

Query: 507 -----SSGDRPEASM--TPDAKHLWLEFSHPVESLALT 537
                SS ++ E+S+   PD  HL LE   P   L L+
Sbjct: 441 KVFSISSQNQQESSVPEVPDVAHLPLEKLGPCLPLDLS 478


>gi|40538728 pleckstrin homology domain containing, family M (with
           RUN domain) member 1 [Homo sapiens]
          Length = 1056

 Score = 34.3 bits (77), Expect = 0.41
 Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 10/134 (7%)

Query: 379 CSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRD 438
           C   A+       S T  G   Q PRP+    AP+  ++++   S   + P   V+    
Sbjct: 352 CEAPAEPLPAQAASGTQDGVHVQEPRPQ----APSPLDLQQPVESTSGQQPSSTVSETAR 407

Query: 439 RSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPS 498
                + L + ++   +GL+     P  T P      S   +   SR+Q    AS     
Sbjct: 408 EVGQGNGLQKAQAHDGAGLKLVVSSP--TSPKNKSWISEDDFYRPSREQPLESAS----D 461

Query: 499 HPLLSNRGSSGDRP 512
           HP+ S RG+ G RP
Sbjct: 462 HPIASYRGTPGSRP 475


>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 602

 Score = 34.3 bits (77), Expect = 0.41
 Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 22/162 (13%)

Query: 203 LRAFLARVREAKEMLQKLRED-EPHLETPRAELDSLGHT---DWARLWVQLMRELRRGVK 258
           L+  L +++E+ + +Q  R++   HL+  RA           +   L  +  +++RR  K
Sbjct: 219 LKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEK 278

Query: 259 LK----KVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELI 314
           L+    K++ Q   PLP E    P E+ +Q +R    +     V G++  +VK +    +
Sbjct: 279 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER-----VAGELQAQVKNNQRISL 333

Query: 315 LDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRL 356
           L+         Q  E R+R    + R   E+I E+ K  ++L
Sbjct: 334 LN---------QRQEERIREQEERLRKQEERIQEQHKSLQQL 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,728,031
Number of Sequences: 37866
Number of extensions: 1548197
Number of successful extensions: 6760
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 6634
Number of HSP's gapped (non-prelim): 174
length of query: 714
length of database: 18,247,518
effective HSP length: 109
effective length of query: 605
effective length of database: 14,120,124
effective search space: 8542675020
effective search space used: 8542675020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.