Guide to the Human Genome
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Name: PLEKHM1 Sequence: fasta or formatted (1056aa) NCBI GI: 40538728
Description:

pleckstrin homology domain containing, family M (with RUN domain) member 1

Referenced in:

Inositol Pathways
Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7         81           2
 C cysteine            3.3         35           1
 D aspartate           4.7         50           2
 E glutamate           7.5         79           2
 F phenylalanine       3.4         36           2
 G glycine             5.9         62           2
 H histidine           3.4         36           2
 I isoleucine          3.6         38           2
 K lysine              4.7         50           3
 L leucine            12.2        129           3
 M methionine          1.2         13           1
 N asparagine          2.8         30           2
 P proline             5.6         59           2
 Q glutamine           6.2         66           2
 R arginine            5.8         61           3
 S serine              9.7        102           3
 T threonine           3.9         41           2
 V valine              5.1         54           2
 W tryptophan          1.0         11           1
 Y tyrosine            2.2         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pleckstrin homology domain containing, family M (wit... 
LOC100293478          0.507   PREDICTED: similar to pleckstrin homology domain co...
LOC100291232          0.478   PREDICTED: hypothetical protein XP_002347841 
PLEKHM3               0.113   pleckstrin homology domain containing, family M, me...
DEF8                  0.064   differentially expressed in FDCP 8 isoform 1 
C13orf18              0.062   hypothetical protein LOC80183 
KIAA0226              0.049   hypothetical protein LOC9711 isoform 1 
KIAA0226              0.049   hypothetical protein LOC9711 isoform 2 
RUNDC2A               0.033   RUN domain containing 2A 
PLEKHM2               0.021   pleckstrin homology domain containing, family M (wi...
RUFY3                 0.016   RUN and FYVE domain containing 3 isoform 2 
RUFY3                 0.016   RUN and FYVE domain containing 3 isoform 1 
RUFY3                 0.016   RUN and FYVE domain containing 3 isoform 3 
DENND5B               0.015   DENN/MADD domain containing 5B 
RUFY1                 0.014   RUN and FYVE domain-containing 1 isoform b 
RUFY1                 0.014   RUN and FYVE domain-containing 1 isoform b 
RUFY1                 0.014   RUN and FYVE domain-containing 1 isoform a 
RUFY2                 0.012   RUN and FYVE domain-containing 2 isoform a 
DENND5A               0.010   RAB6 interacting protein 1 
RUNDC3B               0.009   RUN domain containing 3B isoform c 
RUNDC3B               0.008   RUN domain containing 3B isoform a 
RUNDC3B               0.008   RUN domain containing 3B isoform b 
TNRC18                0.007   trinucleotide repeat containing 18 
SETD1A                0.007   SET domain containing 1A 
MICALL1               0.007   molecule interacting with Rab13 
GLTSCR1               0.007   glioma tumor suppressor candidate region gene 1 [Ho...
ARAP1                 0.006   ArfGAP with RhoGAP domain, ankyrin repeat and PH do...
ARAP1                 0.006   ArfGAP with RhoGAP domain, ankyrin repeat and PH do...
ARAP1                 0.006   ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...
GIT2                  0.006   G protein-coupled receptor kinase interacting ArfGAP...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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