Guide to the Human Genome
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Search of human proteins with 55743077

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
         (387 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s...   783   0.0  
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...   699   0.0  
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]            555   e-158
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]          377   e-105
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]         301   5e-82
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ...   278   5e-75
gi|157649069 ATPase, aminophospholipid transporter (APLT), class...   277   1e-74
gi|117168245 ATPase, aminophospholipid transporter-like, Class I...   266   2e-71
gi|222352161 ATPase, class V, type 10D [Homo sapiens]                 255   4e-68
gi|14424433 ATPase, class V, type 10A [Homo sapiens]                  241   1e-63
gi|149944474 ATPase, class V, type 10B [Homo sapiens]                 229   3e-60
gi|62632750 ATPase, class VI, type 11B [Homo sapiens]                 200   2e-51
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]      187   1e-47
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]      187   1e-47
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]       173   2e-43
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]       173   2e-43
gi|65301139 ATPase, class II, type 9A [Homo sapiens]                  143   2e-34
gi|41327760 ATPase, class II, type 9B [Homo sapiens]                  142   7e-34
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ...    36   0.067
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ...    36   0.067
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ...    36   0.067
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]    35   0.15 
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]              34   0.26 
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...    34   0.26 
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...    32   1.3  
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...    32   1.3  
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]    32   1.3  
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    31   1.7  
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]     30   4.8  
gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo ...    29   8.2  

>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
           sapiens]
          Length = 387

 Score =  783 bits (2022), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 60
           MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY
Sbjct: 1   MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 60

Query: 61  FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 120
           FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN
Sbjct: 61  FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 120

Query: 121 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 180
           GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI
Sbjct: 121 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 180

Query: 181 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240
           PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE
Sbjct: 181 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240

Query: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300
           WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH
Sbjct: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300

Query: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGG 360
           EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGG
Sbjct: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGG 360

Query: 361 PIELFFSMKMKSLRSNEKSSSSCTVNI 387
           PIELFFSMKMKSLRSNEKSSSSCTVNI
Sbjct: 361 PIELFFSMKMKSLRSNEKSSSSCTVNI 387


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
           sapiens]
          Length = 1223

 Score =  699 bits (1804), Expect = 0.0
 Identities = 357/411 (86%), Positives = 363/411 (88%), Gaps = 26/411 (6%)

Query: 1   MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 60
           MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY
Sbjct: 34  MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 93

Query: 61  FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 120
           FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN
Sbjct: 94  FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 153

Query: 121 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 180
           GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI
Sbjct: 154 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 213

Query: 181 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240
           PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE
Sbjct: 214 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 273

Query: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300
           WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH
Sbjct: 274 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 333

Query: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLS----- 355
           EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV  V  +  G S     
Sbjct: 334 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVS-VEVIRLGHSYFINW 392

Query: 356 --------------------RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386
                                E  G +E  FS K  +L  N    + C++N
Sbjct: 393 DKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSIN 443


>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
          Length = 1192

 Score =  555 bits (1431), Expect = e-158
 Identities = 281/408 (68%), Positives = 326/408 (79%), Gaps = 25/408 (6%)

Query: 4   CAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 63
           C++K+  E ER  +ANDREYNEKFQYA N I TSKYNILTFLP+NLFEQFQ VAN YFL 
Sbjct: 3   CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62

Query: 64  LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 123
           LLILQLIP+ISSL+WFTTIVPLVLV+T+TAVKDATDDYFRHKSDNQVNNRQS+VLIN  L
Sbjct: 63  LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKL 122

Query: 124 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 183
           Q E+WMNV VGDIIKLENNQFVAADLLLLSSSEPHGLCY+ETAELDGETN+KVR A+ VT
Sbjct: 123 QNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVT 182

Query: 184 SELG-DISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 242
           SELG DIS+LA FDG V+CE PNNKLDKF G L WK++K  L+N+ ++LRGC+LRNT WC
Sbjct: 183 SELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWC 242

Query: 243 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 302
           FG+VIFAGPDTKLMQNSG+TKFKRTSIDRLMNTLVLWIFGFL+C+G+ILAIGN+IWE + 
Sbjct: 243 FGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT 302

Query: 303 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV------------------ 344
           G +F+ +L W+E   S+ FSGFL+FWSYIIILNTVVPISLYV                  
Sbjct: 303 GDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRK 362

Query: 345 -----RYVPSLTWGLS-RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386
                + +P++    +  E  G IE  FS K  +L  N  +   C++N
Sbjct: 363 MYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSIN 410


>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
          Length = 1251

 Score =  377 bits (968), Expect = e-105
 Identities = 193/369 (52%), Positives = 261/369 (70%), Gaps = 17/369 (4%)

Query: 15  RARANDREYNE-------KF------QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYF 61
           + +ANDR+Y+E       KF      +YA+N IKT KYN  TF+P+NLFEQF+  AN YF
Sbjct: 65  QVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYF 124

Query: 62  LFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLING 121
           L LLILQ +PQIS+L+W+TT+VPL++VL +TA+KD  DD  RHK D ++NNR  +V+ +G
Sbjct: 125 LALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDG 184

Query: 122 ILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIP 181
             +  +W  + VGD+I+L+ N FV AD+LLLSSSEP+ LCY+ETAELDGETN+K + ++ 
Sbjct: 185 RFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE 244

Query: 182 VTSE-LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240
           +T + L     LA FDG + CE PNN+LDKF+GTL+W+   FPL    +LLRGCV+RNT+
Sbjct: 245 ITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTD 304

Query: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300
           +C GLVIFAG DTK+M+NSG+T+FKRT ID LMN +V  IF  L+ +   LAIG+A WE 
Sbjct: 305 FCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEA 364

Query: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGG 360
           +VG     YL +D   D+  + GFL FW YII+LNT+VPISLYV  V  +  G S     
Sbjct: 365 QVG-NSSWYL-YDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVS-VEVIRLGQSHFINW 421

Query: 361 PIELFFSMK 369
            ++++++ K
Sbjct: 422 DLQMYYAEK 430


>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
          Length = 1300

 Score =  301 bits (772), Expect = 5e-82
 Identities = 151/342 (44%), Positives = 220/342 (64%), Gaps = 14/342 (4%)

Query: 15  RARANDREYNEKFQ-----------YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 63
           + +AN+R YN +F+           Y +N I+T+KYN  +FLP+NL+EQF  V+N +FL 
Sbjct: 108 KVQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLI 167

Query: 64  LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 123
           ++ILQ IP IS+L WF+   P+V +L I A +D  DD  RHKSD  +NNR  Q+L+    
Sbjct: 168 IIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSF 227

Query: 124 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 183
           +Q++W ++CVGD++ L  +  V AD+LLL+S+EP  LCY+ET ++DGETN+K RQA+ VT
Sbjct: 228 KQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVT 287

Query: 184 -SELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 242
             EL  I K+A F G V CE PN+++  F G L W + K+ L   N+LLRGC +RNT+ C
Sbjct: 288 HKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTC 347

Query: 243 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 302
           +GLVI+AG DTK+M+N G+   KRT +D LMN LV+ IF  +V + ++LA G      E 
Sbjct: 348 YGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE- 406

Query: 303 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV 344
             +   Y        S     F  FWS++I+L+  +P+S+++
Sbjct: 407 -FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFI 447


>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
           type 8A, member 1 isoform a [Homo sapiens]
          Length = 1164

 Score =  278 bits (712), Expect = 5e-75
 Identities = 147/384 (38%), Positives = 223/384 (58%), Gaps = 31/384 (8%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++ +N + T+KYNI+TFLP  L+ QF+  AN++FLF+ +LQ IP +S    +TT+VPL+ 
Sbjct: 48  KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           +L + A+K+  +D  RHK+DN VN +Q+QVL NG  +   W  V VG+I+K+ N + + A
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+ LSSSEP  +CYIET+ LDGETN+K+RQ +P TS++ D+  L +  G + CE PN  
Sbjct: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227

Query: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
           L  F G +        PL    +LLRG  LRNT+W  G+V++ G DTKLMQNS     K 
Sbjct: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287

Query: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 325
           ++++R+ N  +L +F  L+ M ++ ++G+AIW      +      W   ++    S F L
Sbjct: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342

Query: 326 SFWSYIIILNTVVPISLYV-------------------RYVPSLTWGLSRESG-----GP 361
           +F ++II+ N ++PISL V                    Y P+ T  ++R S      G 
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402

Query: 362 IELFFSMKMKSLRSNEKSSSSCTV 385
           ++  FS K  +L  N      CT+
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTI 426


>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
           type 8A, member 1 isoform b [Homo sapiens]
          Length = 1149

 Score =  277 bits (708), Expect = 1e-74
 Identities = 146/384 (38%), Positives = 223/384 (58%), Gaps = 31/384 (8%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++ +N + T+KYNI+TFLP  L+ QF+  AN++FLF+ +LQ IP +S    +TT+VPL+ 
Sbjct: 48  KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           +L + A+K+  +D  RHK+DN VN +Q+QVL NG  +   W  V VGDI+ ++  +++ A
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           D +LLSSSEP  +CYIET+ LDGETN+K+RQ +P TS++ D+  L +  G + CE PN  
Sbjct: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227

Query: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
           L  F G +        PL    +LLRG  LRNT+W  G+V++ G DTKLMQNS     K 
Sbjct: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287

Query: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 325
           ++++R+ N  +L +F  L+ M ++ ++G+AIW      +      W   ++    S F L
Sbjct: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342

Query: 326 SFWSYIIILNTVVPISLYV-------------------RYVPSLTWGLSRESG-----GP 361
           +F ++II+ N ++PISL V                    Y P+ T  ++R S      G 
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402

Query: 362 IELFFSMKMKSLRSNEKSSSSCTV 385
           ++  FS K  +L  N      CT+
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTI 426


>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
           type 8A, member 2 [Homo sapiens]
          Length = 1188

 Score =  266 bits (680), Expect = 2e-71
 Identities = 142/383 (37%), Positives = 222/383 (57%), Gaps = 29/383 (7%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++  N I T+KY++LTFLP  L+EQ +  AN +FLF+ +LQ IP +S    +TT+VPL++
Sbjct: 67  KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           +LTI  +K+  +D+ RHK+DN VN +++ VL NG+     W  V VGDI+K+ N Q++ A
Sbjct: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           D++LLSSSEP  +CY+ETA LDGETN+K+RQ +  T+++     L K  G + CE PN  
Sbjct: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRH 246

Query: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
           L  F+G L    ++   L    +LLRG  LRNT+W FG+V++ G DTKLMQNS +   KR
Sbjct: 247 LYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKR 306

Query: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLS 326
           ++++++ N  +L +FG L+ M ++ + G   W    G +       D   D+  +    +
Sbjct: 307 SNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGY----N 362

Query: 327 FWSYIIILNTVVPISLYVR-------------------YVPSLTWGLSRESG-----GPI 362
             ++II+ N ++PISL V                    Y+ + T  ++R S      G +
Sbjct: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422

Query: 363 ELFFSMKMKSLRSNEKSSSSCTV 385
           +  FS K  +L  N  +   C++
Sbjct: 423 KYLFSDKTGTLTCNIMNFKKCSI 445


>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
          Length = 1426

 Score =  255 bits (652), Expect = 4e-68
 Identities = 140/332 (42%), Positives = 205/332 (61%), Gaps = 18/332 (5%)

Query: 25  EKFQ--YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTI 82
           EKF   Y +N I+T+KY +L F+P NLFEQF   AN YFLFL++L  +P + +     T+
Sbjct: 65  EKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM 124

Query: 83  VPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQ-------WMNVCVGD 135
           +PLV+VLTI A+KD  +DY ++K D Q+NN     LI  +  +++       W +V VGD
Sbjct: 125 LPLVVVLTIIAIKDGLEDYRKYKIDKQINN-----LITKVYSRKEKKYIDRCWKDVTVGD 179

Query: 136 IIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKF 195
            I+L  N+ + AD++LL S++P G+C+IET+ LDGE+N+K RQ +   +E        KF
Sbjct: 180 FIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKF 239

Query: 196 DGEVICEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTK 254
              + CE PNN L +F G L +  + +  LS +N+LLRGC +RNTE   G+V++AG +TK
Sbjct: 240 SSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETK 299

Query: 255 LMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIW--EHEVGMRFQVYLPW 312
            M N+   ++KR+ ++R  NT VLW    LV M +  A+G+ IW   +E    F V  P 
Sbjct: 300 AMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEP- 358

Query: 313 DEAVDSAFFSGFLSFWSYIIILNTVVPISLYV 344
           D  + S   +GF  FW+ II+L  ++PISLYV
Sbjct: 359 DGHIISPLLAGFYMFWTMIILLQVLIPISLYV 390


>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
          Length = 1499

 Score =  241 bits (614), Expect = 1e-63
 Identities = 134/342 (39%), Positives = 200/342 (58%), Gaps = 20/342 (5%)

Query: 13  ERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQ 72
           ERR R    ++      A N +KT+KY +L+FLP NLFEQF   AN YF+F+ +L  +P 
Sbjct: 48  ERRRRRGCAQH-----LADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPA 102

Query: 73  ISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQ 125
           +++      + P++ +L ITA +D  +DY RH+SD+++N+       R+ +  +N     
Sbjct: 103 VNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRF--- 159

Query: 126 EQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSE 185
             W  + VGD ++L  N+   AD+LLLSSS+P GLC+IETA LDGETN+K RQ +   SE
Sbjct: 160 --WKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSE 217

Query: 186 LGDISKLAKFDGEVICEPPNNKLDKFSG-TLYWKENKFPLSNQNMLLRGCVLRNTEWCFG 244
           L        F   + CE PNN L +F G  ++    K  L  +N+LLRGC LRNT+   G
Sbjct: 218 LVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVG 277

Query: 245 LVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGM 304
           +VI+AG +TK + N+   ++KR+ ++R MN  VLW    LVCM +  A+G+ +W      
Sbjct: 278 IVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQE 337

Query: 305 RFQV-YLPWDEAVD-SAFFSGFLSFWSYIIILNTVVPISLYV 344
           +  + Y+P  +    S   +   SF + II+L  ++PISLYV
Sbjct: 338 KKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYV 379


>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
          Length = 1461

 Score =  229 bits (584), Expect = 3e-60
 Identities = 128/330 (38%), Positives = 195/330 (59%), Gaps = 22/330 (6%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           +Y  N   T+KY + TFLP NLFEQF   AN YFLFL+IL  +P +       T++PL +
Sbjct: 65  RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124

Query: 88  VLTITAVKDATDDYFRHKSDNQVN-------NRQSQVLINGILQQEQWMNVCVGDIIKLE 140
           VL +  +KD  +D+ RH+ D  +N        R+ Q  +     Q+ W +V VGD I+++
Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYV-----QKCWKDVRVGDFIQMK 179

Query: 141 NNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVI 200
            N+ V AD+LLL SS+P+G+C++ETA LDGETN+K R  +   S+     +   F   ++
Sbjct: 180 CNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV 239

Query: 201 CEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNS 259
           CE PNN L+KF G + +  + +     +++LLRGC +RNTE   G+VI+AG +TK M N+
Sbjct: 240 CEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNN 299

Query: 260 GRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSA 319
              ++KR+ I+R MN  + +  G L+ M +I A+G++IW       F+ + P+D    + 
Sbjct: 300 SGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG----TFEEHPPFDVPDANG 355

Query: 320 FF-----SGFLSFWSYIIILNTVVPISLYV 344
            F      GF  F + II+L  ++PISLYV
Sbjct: 356 SFLPSALGGFYMFLTMIILLQVLIPISLYV 385


>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
          Length = 1177

 Score =  200 bits (509), Expect = 2e-51
 Identities = 129/397 (32%), Positives = 208/397 (52%), Gaps = 47/397 (11%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++  N I +SKY +  F+P NLFEQF+ VAN YFL + ++QL+    + S  T+ +PL  
Sbjct: 38  KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLFF 96

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           V+T+TA+K   +D+ RH SDN+VN     V+ +G L + +  N+ VGDI+++  ++   A
Sbjct: 97  VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+LLSS    G C++ TA LDGETN+K   A+P T+ L  ++ L      + C+ P   
Sbjct: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEAD 216

Query: 208 LDKFSG----TLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTK 263
           L +F G    T   +E   PL  +++LLRG  L+NT+  FG+ ++ G +TK+  N     
Sbjct: 217 LYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKS 276

Query: 264 FKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDE--------- 314
            KR+++++ MNT ++     L+   VI  I    W+ E          WDE         
Sbjct: 277 QKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE--------KWDEPWYNQKTEH 328

Query: 315 AVDSAFFSGFLS-FWSYIIILNTVVPISLYV-----RYVPS--LTWGLS----------- 355
             +S+    F+S F +++++ N ++PISLYV     +++ S  + W L            
Sbjct: 329 QRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQ 388

Query: 356 ------RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386
                  E  G +E  F+ K  +L  NE     C++N
Sbjct: 389 VNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSIN 425


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score =  187 bits (475), Expect = 1e-47
 Identities = 121/393 (30%), Positives = 198/393 (50%), Gaps = 40/393 (10%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           +Y  N I +SKY    F+P NLFEQF+ VAN YFL + ++QLI    + S  T+ +PL  
Sbjct: 44  RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPT-SPVTSGLPLFF 102

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           V+T+TA+K   +D+ RHK+DN +N      + +G L ++Q   + VGDI+ ++ ++    
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+ LSS+   G C++ TA LDGE++ K   A+  T        +      + CE P   
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222

Query: 208 LDKFSG--TLYWKENK---FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
           L KF G   +Y   N     PL ++N+LLRG  L+NTE  FG+ I+ G +TK+  N    
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316
             KR+++++ MN  ++     L+   +I  +   +W+ E   R +   PW       E  
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSE-PFRDE---PWYNQKTESERQ 338

Query: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV-----RYVPS--LTWG---LSRESG------- 359
            + F   F  F +++++ N ++P+S+YV     +++ S  +TW       E+G       
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398

Query: 360 -------GPIELFFSMKMKSLRSNEKSSSSCTV 385
                  G +E  F+ K  +L  N      C +
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCI 431


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score =  187 bits (475), Expect = 1e-47
 Identities = 121/393 (30%), Positives = 198/393 (50%), Gaps = 40/393 (10%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           +Y  N I +SKY    F+P NLFEQF+ VAN YFL + ++QLI    + S  T+ +PL  
Sbjct: 44  RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPT-SPVTSGLPLFF 102

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           V+T+TA+K   +D+ RHK+DN +N      + +G L ++Q   + VGDI+ ++ ++    
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+ LSS+   G C++ TA LDGE++ K   A+  T        +      + CE P   
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222

Query: 208 LDKFSG--TLYWKENK---FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
           L KF G   +Y   N     PL ++N+LLRG  L+NTE  FG+ I+ G +TK+  N    
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316
             KR+++++ MN  ++     L+   +I  +   +W+ E   R +   PW       E  
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSE-PFRDE---PWYNQKTESERQ 338

Query: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV-----RYVPS--LTWG---LSRESG------- 359
            + F   F  F +++++ N ++P+S+YV     +++ S  +TW       E+G       
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398

Query: 360 -------GPIELFFSMKMKSLRSNEKSSSSCTV 385
                  G +E  F+ K  +L  N      C +
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCI 431


>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
          Length = 1119

 Score =  173 bits (439), Expect = 2e-43
 Identities = 98/328 (29%), Positives = 169/328 (51%), Gaps = 16/328 (4%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++  N I +SKY +  FLP NLFEQF+ +AN YFL + ++Q+     + S  T+ +PL  
Sbjct: 42  RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           V+T+TA+K   +D+ RH++DN+VN     ++ N    +++   + VGD+++++ ++    
Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+LLSS    G CY+ TA LDGE+N K   A+  T  L     +      + CE P   
Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220

Query: 208 LDKFSGTLYWKENKF-----PLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
           L KF G +    N        L  +N+LL+G  L+NTE  +G+ ++ G +TK+  N    
Sbjct: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316
             KR+++++ +N  ++     L+    +      +W+           PW       E  
Sbjct: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTP----YNDEPWYNQKTQKERE 336

Query: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV 344
                  F  F S++++ N ++P+S+YV
Sbjct: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYV 364


>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
          Length = 1132

 Score =  173 bits (439), Expect = 2e-43
 Identities = 98/328 (29%), Positives = 169/328 (51%), Gaps = 16/328 (4%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++  N I +SKY +  FLP NLFEQF+ +AN YFL + ++Q+     + S  T+ +PL  
Sbjct: 42  RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
           V+T+TA+K   +D+ RH++DN+VN     ++ N    +++   + VGD+++++ ++    
Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160

Query: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
           DL+LLSS    G CY+ TA LDGE+N K   A+  T  L     +      + CE P   
Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220

Query: 208 LDKFSGTLYWKENKF-----PLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
           L KF G +    N        L  +N+LL+G  L+NTE  +G+ ++ G +TK+  N    
Sbjct: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316
             KR+++++ +N  ++     L+    +      +W+           PW       E  
Sbjct: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTP----YNDEPWYNQKTQKERE 336

Query: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV 344
                  F  F S++++ N ++P+S+YV
Sbjct: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYV 364


>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
          Length = 1047

 Score =  143 bits (361), Expect = 2e-34
 Identities = 99/342 (28%), Positives = 170/342 (49%), Gaps = 32/342 (9%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           +Y  N I   KYN  TFLP  LF QF+   N YFL L   Q +P++   + +T  VPL  
Sbjct: 52  RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 146
           VL +T +++A ++   +  D +VN++  S++   G ++ +   N+ VGD+I +E NQ V 
Sbjct: 112 VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKS-SNIQVGDLIIVEKNQRVP 170

Query: 147 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 206
           AD++ L +SE +G C++ T +LDGET+ K+R  +  T  L   + L +    V  E PN 
Sbjct: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230

Query: 207 KLDKFSGTLYWKENKFPLSN----QNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
            +  F GT   +++  P+S     +N L  G V+ +     G+V++ G + + + N+   
Sbjct: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 322
           + K    D  +N L   +FG LV + +++       +H  G        W          
Sbjct: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVM----VALQHFAGR-------W---------- 328

Query: 323 GFLSFWSYIIILNTVVPISLYVRYVPS---LTWGLSRESGGP 361
            +L    ++++ + ++PISL V         +W + R+S  P
Sbjct: 329 -YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIP 369


>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
          Length = 1147

 Score =  142 bits (357), Expect = 7e-34
 Identities = 92/322 (28%), Positives = 165/322 (51%), Gaps = 29/322 (9%)

Query: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
           ++  N IK  KYN+ TF+P  L+EQF+   N YFL +   Q +P +     +T   PL  
Sbjct: 129 KHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGF 188

Query: 88  VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 146
           VL +T  ++A D++ R + D +VN++  S++ + G +Q +   ++ VGD+I +E NQ + 
Sbjct: 189 VLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS-SDIQVGDLIIVEKNQRIP 247

Query: 147 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 206
           +D++ L +SE  G C+I T +LDGET+ K++ A+  T +L  +  L      V  + P  
Sbjct: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307

Query: 207 KLDKFSGTLYWKENKFP----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
            +  F GT   +++  P    LS +N L    ++ +     G+VI+ G +T+ + N+   
Sbjct: 308 DIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGT-VIGVVIYTGKETRSVMNTSNP 366

Query: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 322
           K K   +D  +N L   +F  LV + +++          VG       PW          
Sbjct: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG-------PW---------- 405

Query: 323 GFLSFWSYIIILNTVVPISLYV 344
            + + + ++++ + ++PISL V
Sbjct: 406 -YRNLFRFLLLFSYIIPISLRV 426


>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
           sapiens]
          Length = 1021

 Score = 35.8 bits (81), Expect = 0.067
 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 9/116 (7%)

Query: 273 MNTLVLWIFGFLVCMGVILAIG--NAIWEHEVGMR--FQVYLPWDE---AVDSAFFSGFL 325
           +NT+   I  F +C   ++     +A   +  G R  FQ Y  W     A+ S      L
Sbjct: 525 LNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLL 584

Query: 326 SFWSYIIILNTVVPISLYVRY-VPSLTWGLSRESGG-PIELFFSMKMKSLRSNEKS 379
           ++W+ +I +  V+ + LYV Y  P + WG S ++G   + L +S+ +  +  + K+
Sbjct: 585 TWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKN 640


>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
           sapiens]
          Length = 1029

 Score = 35.8 bits (81), Expect = 0.067
 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 9/116 (7%)

Query: 273 MNTLVLWIFGFLVCMGVILAIG--NAIWEHEVGMR--FQVYLPWDE---AVDSAFFSGFL 325
           +NT+   I  F +C   ++     +A   +  G R  FQ Y  W     A+ S      L
Sbjct: 524 LNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLL 583

Query: 326 SFWSYIIILNTVVPISLYVRY-VPSLTWGLSRESGG-PIELFFSMKMKSLRSNEKS 379
           ++W+ +I +  V+ + LYV Y  P + WG S ++G   + L +S+ +  +  + K+
Sbjct: 584 TWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKN 639


>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
           sapiens]
          Length = 1030

 Score = 35.8 bits (81), Expect = 0.067
 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 9/116 (7%)

Query: 273 MNTLVLWIFGFLVCMGVILAIG--NAIWEHEVGMR--FQVYLPWDE---AVDSAFFSGFL 325
           +NT+   I  F +C   ++     +A   +  G R  FQ Y  W     A+ S      L
Sbjct: 525 LNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLL 584

Query: 326 SFWSYIIILNTVVPISLYVRY-VPSLTWGLSRESGG-PIELFFSMKMKSLRSNEKS 379
           ++W+ +I +  V+ + LYV Y  P + WG S ++G   + L +S+ +  +  + K+
Sbjct: 585 TWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKN 640


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 11/100 (11%)

Query: 85  LVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQEQWMNVCVGDII 137
           L +VL    +      Y++    +++ +       +Q+ V+  G   Q     V VGD++
Sbjct: 130 LGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLV 189

Query: 138 KLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVR 177
           +++    V ADL ++SS   HG C ++ + L GE+  + R
Sbjct: 190 EVKGGDRVPADLRIISS---HG-CKVDNSSLTGESEPQTR 225


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 4/65 (6%)

Query: 113 RQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGET 172
           +Q+ V+  G   Q     V VGD+++++    V ADL ++S+   HG C ++ + L GE+
Sbjct: 157 QQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISA---HG-CKVDNSSLTGES 212

Query: 173 NMKVR 177
             + R
Sbjct: 213 EPQTR 217


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 22/100 (22%), Positives = 47/100 (47%), Gaps = 11/100 (11%)

Query: 85  LVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQEQWMNVCVGDII 137
           L +VL++  +      Y++    +++         +Q+ V+  G   Q     V +GD++
Sbjct: 140 LSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199

Query: 138 KLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVR 177
           +++    V ADL L+S+      C ++ + L GE+  + R
Sbjct: 200 EIKGGDRVPADLRLISAQG----CKVDNSSLTGESEPQSR 235


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
           sapiens]
          Length = 1023

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 113 RQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGET 172
           +Q+ V+ NG         V VGD+++++    + ADL ++S++     C ++ + L GE+
Sbjct: 167 QQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANG----CKVDNSSLTGES 222

Query: 173 NMKVR 177
             + R
Sbjct: 223 EPQTR 227


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 113 RQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGET 172
           +Q+ V+ NG         V VGD+++++    + ADL ++S++     C ++ + L GE+
Sbjct: 136 QQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANG----CKVDNSSLTGES 191

Query: 173 NMKVR 177
             + R
Sbjct: 192 EPQTR 196


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 113 RQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGET 172
           +Q+ V+ NG         V VGD+++++    + ADL ++S++     C ++ + L GE+
Sbjct: 167 QQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANG----CKVDNSSLTGES 222

Query: 173 NMKVR 177
             + R
Sbjct: 223 EPQTR 227


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
           sapiens]
          Length = 2161

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 13/38 (34%), Positives = 21/38 (55%)

Query: 228 NMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFK 265
           N  L  C L N E C  ++++ G D  +  N+G+T F+
Sbjct: 348 NTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQ 385


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 21/98 (21%), Positives = 46/98 (46%), Gaps = 10/98 (10%)

Query: 86  VLVLTITAVKDATDDYFRHKSDNQVNN------RQSQVLINGILQQEQWMNVCVGDIIKL 139
           + ++ +  V      Y   KS N + +      +Q+ V+ +G   Q     + VGD++++
Sbjct: 145 IALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEM 204

Query: 140 ENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVR 177
           +    V AD+ +L++      C ++ + L GE+  + R
Sbjct: 205 KGGDRVPADIRILAAQG----CKVDNSSLTGESEPQTR 238


>gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo
           sapiens]
          Length = 2146

 Score = 28.9 bits (63), Expect = 8.2
 Identities = 33/165 (20%), Positives = 62/165 (37%), Gaps = 21/165 (12%)

Query: 215 LYWKENKFPLSNQNMLLRGC-----VLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSI 269
           LY ++  +P    ++ LR       +     W + + +      K +     T+ + T  
Sbjct: 527 LYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTL----TVKAVVREKETRLRDTMR 582

Query: 270 DRLMNTLVLWIFGFLVCMG----------VILAIGNAIWEHEVGMRFQVYLPWDEA--VD 317
              ++  VLW+  FL C+G          ++L +G+ +     G+ F     +  A    
Sbjct: 583 AMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSHPGVVFLFLAAFAVATVTQ 642

Query: 318 SAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGGPI 362
           S   S F S  +       +   SLY+ YV  + W     +GG +
Sbjct: 643 SFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLPAGGRV 687


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,699,715
Number of Sequences: 37866
Number of extensions: 539668
Number of successful extensions: 1206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1145
Number of HSP's gapped (non-prelim): 33
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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