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Search of human proteins with 55741632
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55741632 fibronectin type III and SPRY domain containing 2
[Homo sapiens]
(749 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 1541 0.0
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 333 3e-91
gi|223890257 midline 2 isoform 1 [Homo sapiens] 177 3e-44
gi|148833499 midline 1 [Homo sapiens] 124 4e-28
gi|4557753 midline 1 [Homo sapiens] 124 4e-28
gi|15451852 midline 1 [Homo sapiens] 124 4e-28
gi|223890259 midline 2 isoform 2 [Homo sapiens] 123 7e-28
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 95 3e-19
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 82 2e-15
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 80 5e-15
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 80 5e-15
gi|63054855 erythroblast membrane-associated protein precursor [... 80 7e-15
gi|19923536 erythroblast membrane-associated protein precursor [... 80 7e-15
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 79 2e-14
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 76 1e-13
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 76 1e-13
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 76 1e-13
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 76 1e-13
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ... 75 2e-13
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo... 75 2e-13
gi|46409324 SPRY domain containing 4 [Homo sapiens] 74 6e-13
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 73 8e-13
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 73 8e-13
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 73 8e-13
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 73 1e-12
gi|229577048 butyrophilin-like 8 isoform 6 [Homo sapiens] 72 2e-12
gi|229577043 butyrophilin-like 8 isoform 5 [Homo sapiens] 72 2e-12
gi|229577033 butyrophilin-like 8 isoform 3 precursor [Homo sapiens] 72 2e-12
gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens] 72 2e-12
gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Hom... 72 2e-12
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 1541 bits (3989), Expect = 0.0
Identities = 749/749 (100%), Positives = 749/749 (100%)
Query: 1 MEEESGEELGLDRSTPKDFHFYHMDLYDSEDRLHLFPEENTRMRKVVQAEMANESRGAGD 60
MEEESGEELGLDRSTPKDFHFYHMDLYDSEDRLHLFPEENTRMRKVVQAEMANESRGAGD
Sbjct: 1 MEEESGEELGLDRSTPKDFHFYHMDLYDSEDRLHLFPEENTRMRKVVQAEMANESRGAGD 60
Query: 61 GKAQRDLQEEVDELVHLYGLEDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDW 120
GKAQRDLQEEVDELVHLYGLEDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDW
Sbjct: 61 GKAQRDLQEEVDELVHLYGLEDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDW 120
Query: 121 RLSGEAAEAEDLGFGGWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFC 180
RLSGEAAEAEDLGFGGWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFC
Sbjct: 121 RLSGEAAEAEDLGFGGWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFC 180
Query: 181 VTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEV 240
VTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEV
Sbjct: 181 VTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEV 240
Query: 241 FITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLD 300
FITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLD
Sbjct: 241 FITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLD 300
Query: 301 TCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVE 360
TCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVE
Sbjct: 301 TCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVE 360
Query: 361 QLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTD 420
QLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTD
Sbjct: 361 QLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTD 420
Query: 421 QAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIR 480
QAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIR
Sbjct: 421 QAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIR 480
Query: 481 SCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYII 540
SCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYII
Sbjct: 481 SCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYII 540
Query: 541 YVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSP 600
YVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSP
Sbjct: 541 YVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSP 600
Query: 601 SDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRH 660
SDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRH
Sbjct: 601 SDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRH 660
Query: 661 TFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHE 720
TFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHE
Sbjct: 661 TFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHE 720
Query: 721 FVHPCFSLEKPGCLKVHNGISMPKHVTFY 749
FVHPCFSLEKPGCLKVHNGISMPKHVTFY
Sbjct: 721 FVHPCFSLEKPGCLKVHNGISMPKHVTFY 749
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 333 bits (854), Expect = 3e-91
Identities = 195/584 (33%), Positives = 306/584 (52%), Gaps = 23/584 (3%)
Query: 168 EEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQI 227
++E ++ D +C TCK PI A KVF HK+HEV L+ A+ + K ++ + + L+++
Sbjct: 3501 QKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQEKS 3560
Query: 228 IEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEA 287
+ +E F + +E F T+EEN K E+ E E+++ + +Y+EK Q+ E KK+K+E
Sbjct: 3561 LRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKMEF 3620
Query: 288 LYGQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDVE--IS 344
L+ Q+V +++DT K+ +ETI E ++ F+ + +RL +++ +E +
Sbjct: 3621 LHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSAMESTASLEKMPA 3680
Query: 345 AQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVES 404
A FE + +Q+ + + P P + PQ PNSAT +++ V WS+ +D ++S
Sbjct: 3681 AFSLFEHYDDSSARSDQM---LKQVAVPQPPRLEPQEPNSATSTTIAVYWSMNKEDVIDS 3737
Query: 405 YQL--SYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSER 462
+Q+ P D E+ +TVKE+YC +L P+ Y+ WV A N G S SER
Sbjct: 3738 FQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSER 3797
Query: 463 AVYMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVG 522
A++ TAPS P+I+ ++ C I W ++YT+E + SPE G+ S G
Sbjct: 3798 AIFRTAPSTPVIRAEDCTVCWNTATIRWRPTTPEATETYTLEYCRQHSPEGEGL-RSFSG 3856
Query: 523 IPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISED 582
I + V LQP +Y YVRA+N G S +SE A + T G+ F L ++T HP L IS
Sbjct: 3857 IKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPALHISSS 3916
Query: 583 GLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFAD 642
G ERR T +V+G +P G HYWE V + YR+G+ +
Sbjct: 3917 GTVISFGERR-----------RLTEIPSVLGEELPSCGQHYWETTVTDCPAYRLGICSSS 3965
Query: 643 VRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSF 702
+ LG SW M S +Y F ++ D+ +T P ++GILLDY + +L F
Sbjct: 3966 AVQAGALGQGETSWYMH---CSEPQRYTFFYSGIVSDVHVTERPARVGILLDYNNQRLIF 4022
Query: 703 FNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
N + Q L+ + +E VHP F+LEKPG +H GI P V
Sbjct: 4023 INAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSV 4066
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 177 bits (449), Expect = 3e-44
Identities = 155/584 (26%), Positives = 255/584 (43%), Gaps = 73/584 (12%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
+ E E +++CV+ I A K+ H++H+V LN+ E K + N+ L K+ E
Sbjct: 197 DHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSE 256
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+EN L ++ VE N E +E++E + Q+ + + E K KL L
Sbjct: 257 LENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLA 316
Query: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Q+ +C + L+ L+ E + E ++ F++ A +A+R+ + + +I+
Sbjct: 317 QQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN 376
Query: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
FE+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W + ++ SY+
Sbjct: 377 DAFENFALDFSREKKLLEGLDYLTAPNPPSIREELC-TASHDTITVHWISDDEFSISSYE 435
Query: 407 LSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYM 466
L Y T QA F + +++CS + W
Sbjct: 436 LQYTIF------TGQANF---ISKSWCS---------WGLW------------------- 458
Query: 467 TAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTC 526
P I K KE SC L G N VDS+ + P +V G
Sbjct: 459 ----PEIRKCKEAVSCSR--LAGAPRGLYNSVDSWMIV------PNIKQNHYTVHG---- 502
Query: 527 ESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTA 586
LQ G YI V+A+N G S SEP + T F+L+ H L IS DGL
Sbjct: 503 -----LQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQM 556
Query: 587 VRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQ 646
+ E + +P T C GN+ G HYWEV + Y +G+A+ K
Sbjct: 557 EKDESSLK-KSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKN 615
Query: 647 EDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPP--KKIGILLDYEHSKLSFFN 704
E +G N SW SR F+ ++ + VPP K++G+LLDY+++ LSF++
Sbjct: 616 EWIGKNASSWVF------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYD 669
Query: 705 VDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTF 748
S HL+TF V P F++ L + +G+ P + +
Sbjct: 670 PANSLHLHTFDVTFILPVCPTFTIWNKS-LMILSGLPAPDFIDY 712
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 124 bits (310), Expect = 4e-28
Identities = 85/290 (29%), Positives = 136/290 (46%), Gaps = 15/290 (5%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520
Y+TAP+PP I+ + + + + + W S + V SY ++ T QA +S
Sbjct: 378 YLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSW 437
Query: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
+ +P + +V LQ G YI V+A+N G S SEP + T F+L+ + H
Sbjct: 438 MIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQPFKLDPKSAHRK 496
Query: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636
L +S D LT R E + + +P V GN+ G HYWEV + Y +
Sbjct: 497 LKVSHDNLTVERDESSSK-KSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAI 555
Query: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYE 696
G+A+ K E +G N SW + + + HN I +++GILLDY+
Sbjct: 556 GLAYKSAPKHEWIGKNSASWAL----CRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYD 611
Query: 697 HSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
+ ++F++ S HLYTF + V P F++ CL + G+ +P H+
Sbjct: 612 NGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNK-CLTIITGLPIPDHL 660
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/311 (25%), Positives = 142/311 (45%), Gaps = 11/311 (3%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
E E+E +++CVT I A K+ H++H+V L+E + K + N+ L K+ E
Sbjct: 177 EHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTE 236
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+E L + VE N +QE + ++E + Q+ + + E K +L L
Sbjct: 237 LETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLA 296
Query: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Q+ +C + ++ L+ E E + F++ A + +R+ + + EI+
Sbjct: 297 QQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLN 356
Query: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
F+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W+ + +V SY+
Sbjct: 357 DTFDTFALDFSREKKLLECLDYLTAPNPPTIREEL-CTASYDTITVHWTSDDEFSVVSYE 415
Query: 407 LSY------RPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460
L Y V D +K+ + +V L T+Y F V A N+AG S SS
Sbjct: 416 LQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSS 474
Query: 461 ERAVYMTAPSP 471
E T P
Sbjct: 475 EPGKLKTNSQP 485
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 124 bits (310), Expect = 4e-28
Identities = 85/290 (29%), Positives = 136/290 (46%), Gaps = 15/290 (5%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520
Y+TAP+PP I+ + + + + + W S + V SY ++ T QA +S
Sbjct: 378 YLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSW 437
Query: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
+ +P + +V LQ G YI V+A+N G S SEP + T F+L+ + H
Sbjct: 438 MIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQPFKLDPKSAHRK 496
Query: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636
L +S D LT R E + + +P V GN+ G HYWEV + Y +
Sbjct: 497 LKVSHDNLTVERDESSSK-KSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAI 555
Query: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYE 696
G+A+ K E +G N SW + + + HN I +++GILLDY+
Sbjct: 556 GLAYKSAPKHEWIGKNSASWAL----CRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYD 611
Query: 697 HSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
+ ++F++ S HLYTF + V P F++ CL + G+ +P H+
Sbjct: 612 NGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNK-CLTIITGLPIPDHL 660
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/311 (25%), Positives = 142/311 (45%), Gaps = 11/311 (3%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
E E+E +++CVT I A K+ H++H+V L+E + K + N+ L K+ E
Sbjct: 177 EHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTE 236
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+E L + VE N +QE + ++E + Q+ + + E K +L L
Sbjct: 237 LETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLA 296
Query: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Q+ +C + ++ L+ E E + F++ A + +R+ + + EI+
Sbjct: 297 QQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLN 356
Query: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
F+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W+ + +V SY+
Sbjct: 357 DTFDTFALDFSREKKLLECLDYLTAPNPPTIREEL-CTASYDTITVHWTSDDEFSVVSYE 415
Query: 407 LSY------RPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460
L Y V D +K+ + +V L T+Y F V A N+AG S SS
Sbjct: 416 LQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSS 474
Query: 461 ERAVYMTAPSP 471
E T P
Sbjct: 475 EPGKLKTNSQP 485
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 124 bits (310), Expect = 4e-28
Identities = 85/290 (29%), Positives = 136/290 (46%), Gaps = 15/290 (5%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520
Y+TAP+PP I+ + + + + + W S + V SY ++ T QA +S
Sbjct: 378 YLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSW 437
Query: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
+ +P + +V LQ G YI V+A+N G S SEP + T F+L+ + H
Sbjct: 438 MIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQPFKLDPKSAHRK 496
Query: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636
L +S D LT R E + + +P V GN+ G HYWEV + Y +
Sbjct: 497 LKVSHDNLTVERDESSSK-KSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAI 555
Query: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYE 696
G+A+ K E +G N SW + + + HN I +++GILLDY+
Sbjct: 556 GLAYKSAPKHEWIGKNSASWAL----CRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYD 611
Query: 697 HSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
+ ++F++ S HLYTF + V P F++ CL + G+ +P H+
Sbjct: 612 NGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNK-CLTIITGLPIPDHL 660
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/311 (25%), Positives = 142/311 (45%), Gaps = 11/311 (3%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
E E+E +++CVT I A K+ H++H+V L+E + K + N+ L K+ E
Sbjct: 177 EHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTE 236
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+E L + VE N +QE + ++E + Q+ + + E K +L L
Sbjct: 237 LETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLA 296
Query: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Q+ +C + ++ L+ E E + F++ A + +R+ + + EI+
Sbjct: 297 QQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLN 356
Query: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
F+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W+ + +V SY+
Sbjct: 357 DTFDTFALDFSREKKLLECLDYLTAPNPPTIREEL-CTASYDTITVHWTSDDEFSVVSYE 415
Query: 407 LSY------RPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460
L Y V D +K+ + +V L T+Y F V A N+AG S SS
Sbjct: 416 LQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSS 474
Query: 461 ERAVYMTAPSP 471
E T P
Sbjct: 475 EPGKLKTNSQP 485
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 123 bits (308), Expect = 7e-28
Identities = 87/294 (29%), Positives = 138/294 (46%), Gaps = 19/294 (6%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520
Y+TAP+PP I+ + + + + + W S + + SY ++ T QA +S
Sbjct: 398 YLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSW 457
Query: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
+ +P + +V LQ G YI V+A+N G S SEP + T F+L+ H
Sbjct: 458 MIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQPFKLDPKMTHKK 516
Query: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636
L IS DGL + E + +P T C GN+ G HYWEV + Y +
Sbjct: 517 LKISNDGLQMEKDESSLK-KSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAI 575
Query: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPP--KKIGILLD 694
G+A+ K E +G N SW SR F+ ++ + VPP K++G+LLD
Sbjct: 576 GIAYKSAPKNEWIGKNASSWVF------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLD 629
Query: 695 YEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTF 748
Y+++ LSF++ S HL+TF V P F++ L + +G+ P + +
Sbjct: 630 YDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKS-LMILSGLPAPDFIDY 682
Score = 100 bits (249), Expect = 5e-21
Identities = 79/311 (25%), Positives = 145/311 (46%), Gaps = 11/311 (3%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
+ E E +++CV+ I A K+ H++H+V LN+ E K + N+ L K+ E
Sbjct: 197 DHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSE 256
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+EN L ++ VE N E +E++E + Q+ + + E K KL L
Sbjct: 257 LENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLA 316
Query: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Q+ +C + L+ L+ E + E ++ F++ A +A+R+ + + +I+
Sbjct: 317 QQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN 376
Query: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
FE+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W + ++ SY+
Sbjct: 377 DAFENFALDFSREKKLLEGLDYLTAPNPPSIREEL-CTASHDTITVHWISDDEFSISSYE 435
Query: 407 LSYRPVQDSS------PGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460
L Y + D +K+ + +V L T+Y F V A N+AG S +S
Sbjct: 436 LQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNS 494
Query: 461 ERAVYMTAPSP 471
E T P
Sbjct: 495 EPTRLKTNSQP 505
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 94.7 bits (234), Expect = 3e-19
Identities = 61/233 (26%), Positives = 118/233 (50%), Gaps = 15/233 (6%)
Query: 147 REAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLN 206
+E+ R H +A + C EE EEE +++C++C+ P + KVF HK+ EV PL
Sbjct: 110 QESSRPLHSKAEQHLMC-----EEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLP 164
Query: 207 EALESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETL 266
+ K E+ + L ++ +EEV T+E+N +Q+Q + + L
Sbjct: 165 TIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVL 224
Query: 267 AQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAV 325
++ E +QAL +++EKL+ + G + G++L+ +L+E+ I+ M + +++ A
Sbjct: 225 EERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAK 284
Query: 326 AMADRLGKFLKTKTDVEISAQPE-----FEDQTLDFSDVEQLMGSINTIPAPS 373
+ +++G K VE++ +PE E T+ V +++ +I+ P S
Sbjct: 285 ELINKVGAMSK----VELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGAS 333
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 82.0 bits (201), Expect = 2e-15
Identities = 66/310 (21%), Positives = 141/310 (45%), Gaps = 20/310 (6%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
E E E +++C C+ P+ K+ H H V ++ A ++ K+++ K++ L + +
Sbjct: 214 EHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQ 273
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+++ + L + E N + ++ +H+ ++ E L ++ ++A+ KK +L+
Sbjct: 274 VKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQ 333
Query: 290 GQLVSCGENLDT------CKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEI 343
Q+ L+ +E+++ ++ C F++ A + R+ K ++
Sbjct: 334 TQMEEYQGLLENNGLVGYAQEVLKETDQSC------FVQTAKQLHLRIQKATESLKSFRP 387
Query: 344 SAQPEFEDQTLDFSDVEQLMGSINTIPAP-SAPVINPQVPNSATGSSVRVCWSLYSDDTV 402
+AQ FED ++ S +L+G ++ + P IN + S ++ + W D
Sbjct: 388 AAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEE--QSKVYNNALINWHHPEKDKA 445
Query: 403 ESYQLSYRPV-QDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSE 461
+SY L YR + +D ++ E T K + +L ++ Y F V A+ + SP S
Sbjct: 446 DSYVLEYRKINRDDEMSWNEIEVCGTSK----IIQDLENSSTYAFRVRAYKGSICSPCSR 501
Query: 462 RAVYMTAPSP 471
+ T P+P
Sbjct: 502 ELILHTPPAP 511
Score = 47.4 bits (111), Expect = 5e-05
Identities = 77/368 (20%), Positives = 139/368 (37%), Gaps = 53/368 (14%)
Query: 419 TDQAEFTVTVKETYCSVTNLVPN---------TQYEFWVTAHNRAGPSPSSERAVYMTAP 469
TDQ+ F T K+ + + + T +E +V ++ E + + +
Sbjct: 359 TDQSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQ-TELLGELSFFSSGI 417
Query: 470 SPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESV 529
P I ++ + A LI W + DSY +E + + E V T + +
Sbjct: 418 DVPEINEEQSKVYNNA-LINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEV-CGTSKII 475
Query: 530 VQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGS--YFRLNKDTC-----HPWLTISED 582
L+ +Y VRA S S +HT + + L + C H L + D
Sbjct: 476 QDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRD 535
Query: 583 GLTAVRSERRTPARELSPSDT----HFTRCVAVMGNLIPVRGHHYWEVEVDEHLDY-RVG 637
R E R L ++ ++T ++G+ +G H+W V+ + +VG
Sbjct: 536 -----RVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVG 590
Query: 638 VAFADV--------------RKQEDLGAN------CLSWCMRHTFASSRHKYEFLHNRTT 677
VA +D R ++D G + C T + + F+ T
Sbjct: 591 VASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPT 650
Query: 678 ----PDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGC 733
P+ R+ P IGI LD + K+ F+++D + LY ++P F+L G
Sbjct: 651 SSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGG 710
Query: 734 LKVHNGIS 741
+++ I+
Sbjct: 711 IQLEEPIT 718
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNL-NPVDSYTVE--------LTQAESPEASG 515
++ P P I E + +V + W N +D + +E L + +
Sbjct: 161 FLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWE 220
Query: 516 VTESVVGIPTCESVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLN----- 569
+ +++ G T ++ L+ Y+ + VRA N S+P T+ T F L+
Sbjct: 221 IIDNIKG--TEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSH 278
Query: 570 -----KDTCHPWLTISEDGLTAVRSERRTPARELSPS-----------------DTHFTR 607
+DTC W G + + R +PS D
Sbjct: 279 LNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE 338
Query: 608 CVAVMGNLIPVRGHHYWEVEVDEHL-DYRVGVAFADVRKQEDLGANCLSWCMRHTFASSR 666
V+G+ G HYWEV+ + Y VGVA+ + K + LG SWC+ H +
Sbjct: 339 SYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCI-HVNNWLQ 397
Query: 667 HKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726
+ + HN + +TVP +KIG+ D++ +LSF++ + Q LY+F + + V P F
Sbjct: 398 NTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF 456
Query: 727 SLEKPGCLKVHNGISMPKHV 746
+ G L + G+ +P V
Sbjct: 457 MVWCGG-LSLSTGMQVPSAV 475
Score = 69.3 bits (168), Expect = 1e-11
Identities = 57/253 (22%), Positives = 112/253 (44%), Gaps = 8/253 (3%)
Query: 209 LESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQ 268
++S K+ + + + L + E++NF + L V+EN + ++ + L +
Sbjct: 1 MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60
Query: 269 KYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELME-TIEEMCHEEKVDFIKDAVAM 327
E I + +++ K + L Q+ C L+ +EL+E + +E +F K A +
Sbjct: 61 VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120
Query: 328 ADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATG 387
DR+ + ++ +DFS Q++ ++ +P P AP I+P V
Sbjct: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDP-VECLVAD 179
Query: 388 SSVRVCWSLYSDDT-VESYQLSYRPVQ-DSSPGTDQA---EFTVTVKETYCSVTNLVPNT 442
+SV V W + +D ++ + L +R D P E +K T +++ L ++
Sbjct: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDS 239
Query: 443 QY-EFWVTAHNRA 454
+Y F V A N+A
Sbjct: 240 KYMNFRVRACNKA 252
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNL-NPVDSYTVE--------LTQAESPEASG 515
++ P P I E + +V + W N +D + +E L + +
Sbjct: 193 FLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWE 252
Query: 516 VTESVVGIPTCESVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLN----- 569
+ +++ G T ++ L+ Y+ + VRA N S+P T+ T F L+
Sbjct: 253 IIDNIKG--TEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSH 310
Query: 570 -----KDTCHPWLTISEDGLTAVRSERRTPARELSPS-----------------DTHFTR 607
+DTC W G + + R +PS D
Sbjct: 311 LNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE 370
Query: 608 CVAVMGNLIPVRGHHYWEVEVDEHL-DYRVGVAFADVRKQEDLGANCLSWCMRHTFASSR 666
V+G+ G HYWEV+ + Y VGVA+ + K + LG SWC+ H +
Sbjct: 371 SYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCI-HVNNWLQ 429
Query: 667 HKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726
+ + HN + +TVP +KIG+ D++ +LSF++ + Q LY+F + + V P F
Sbjct: 430 NTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF 488
Query: 727 SLEKPGCLKVHNGISMPKHV 746
+ G L + G+ +P V
Sbjct: 489 MVWCGG-LSLSTGMQVPSAV 507
Score = 67.0 bits (162), Expect = 6e-11
Identities = 56/255 (21%), Positives = 112/255 (43%), Gaps = 8/255 (3%)
Query: 207 EALESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETL 266
E++ ++ + + + L + E++NF + L V+EN + ++ + L
Sbjct: 31 ESINLQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSIL 90
Query: 267 AQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELME-TIEEMCHEEKVDFIKDAV 325
+ E I + +++ K + L Q+ C L+ +EL+E + +E +F K A
Sbjct: 91 DEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAAR 150
Query: 326 AMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSA 385
+ DR+ + ++ +DFS Q++ ++ +P P AP I+P V
Sbjct: 151 QIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDP-VECLV 209
Query: 386 TGSSVRVCWSLYSDDT-VESYQLSYRPVQ-DSSPGTDQA---EFTVTVKETYCSVTNLVP 440
+SV V W + +D ++ + L +R D P E +K T +++ L
Sbjct: 210 ADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKF 269
Query: 441 NTQY-EFWVTAHNRA 454
+++Y F V A N+A
Sbjct: 270 DSKYMNFRVRACNKA 284
>gi|63054855 erythroblast membrane-associated protein precursor
[Homo sapiens]
Length = 475
Score = 80.1 bits (196), Expect = 7e-15
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ DT HP L +SED +RR P + + F V+++G+ G HYWEV
Sbjct: 242 LDPDTAHPKLILSEDQRCVRLGDRRQPVPD---NPQRFDFVVSILGSEYFTTGCHYWEVY 298
Query: 628 VDEHLDYRVGVAFADVRKQEDLGANCLS--WCMRHTFASSRHKYEFLHNRTTPDIRITVP 685
V + + +GV V ++ + A+ + W +R S ++YE L + T R+ P
Sbjct: 299 VGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQ---SRGNEYEALTSPQT-SFRLKEP 354
Query: 686 PKKIGILLDYEHSKLSFFNVDLSQHLYT----FSCQLHEFVHPC 725
P+ +GI LDYE +SF+NV H++T FS L F PC
Sbjct: 355 PRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPC 398
>gi|19923536 erythroblast membrane-associated protein precursor
[Homo sapiens]
Length = 475
Score = 80.1 bits (196), Expect = 7e-15
Identities = 54/164 (32%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ DT HP L +SED +RR P + + F V+++G+ G HYWEV
Sbjct: 242 LDPDTAHPKLILSEDQRCVRLGDRRQPVPD---NPQRFDFVVSILGSEYFTTGCHYWEVY 298
Query: 628 VDEHLDYRVGVAFADVRKQEDLGANCLS--WCMRHTFASSRHKYEFLHNRTTPDIRITVP 685
V + + +GV V ++ + A+ + W +R S ++YE L + T R+ P
Sbjct: 299 VGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQ---SRGNEYEALTSPQT-SFRLKEP 354
Query: 686 PKKIGILLDYEHSKLSFFNVDLSQHLYT----FSCQLHEFVHPC 725
P+ +GI LDYE +SF+NV H++T FS L F PC
Sbjct: 355 PRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPC 398
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/266 (24%), Positives = 123/266 (46%), Gaps = 20/266 (7%)
Query: 209 LESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQ 268
+E ++ + K + L + E+++F L+++ + VE N K +++ E+ + + L +
Sbjct: 1 MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60
Query: 269 KYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHE-EKVDF------I 321
E + + + + + L QL +C L++ +EL+ET + + DF I
Sbjct: 61 LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120
Query: 322 KDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQV 381
KD V MA LK K +S +DF+ Q++ ++ +P PSAPVI+
Sbjct: 121 KDGVTMAPAFRLSLKAKVSDNMS------HLMVDFAQERQMLQALKFLPVPSAPVID-LA 173
Query: 382 PNSATGSSVRVCWSLYSDDT-VESYQLSYRPVQDSSP---GTDQAEFTVT-VKETYCSVT 436
+ + V + W + +D+ ++ Y L YR P DQ + +++T ++T
Sbjct: 174 ESLVADNCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233
Query: 437 NLVPNTQY-EFWVTAHNRAGPSPSSE 461
L + +Y F V A N+A SE
Sbjct: 234 GLKFDMKYMNFRVKACNKAVAGEFSE 259
Score = 74.3 bits (181), Expect = 4e-13
Identities = 78/321 (24%), Positives = 128/321 (39%), Gaps = 42/321 (13%)
Query: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNP-VDSYTVELTQAESPEASGVTES---- 519
++ PS P+I E + V + W + + +D Y +E + + E
Sbjct: 161 FLPVPSAPVIDLAESLVADNCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWM 220
Query: 520 -VVGIPTCE-SVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576
+ GI E ++ L+ Y+ + V+A N SEP T+ T FRL+ T H
Sbjct: 221 VIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQN 280
Query: 577 LTISE--------------------DGLTAVRSERRTPAR-----ELSPS-----DTHFT 606
L + + DG S +PAR + PS D
Sbjct: 281 LRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTA 340
Query: 607 RCVAVMGNLIPVRGHHYWEVEVD-EHLDYRVGVAFADVRKQEDLGANCLSWCMRHTFASS 665
V+G+ + G HYWEV + + + VGVA+ + + E LG SWC+ H
Sbjct: 341 ESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCL-HVNNWL 399
Query: 666 RHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPC 725
+ + H + VP +G+ D+ LSF+N Q L+TF + + + P
Sbjct: 400 QVSFTAKHANKVKVLDAPVPDC-LGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPA 458
Query: 726 FSLEKPGCLKVHNGISMPKHV 746
F++ G +V G+ +P V
Sbjct: 459 FTV-WCGSFQVTTGLQVPSAV 478
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 76.3 bits (186), Expect = 1e-13
Identities = 56/161 (34%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +SED + E R R+L + FT V+ G HYWEVE
Sbjct: 311 LDPETAHPNLVLSEDRKSVKFVETRL--RDLPDTPRRFTFYPCVLATEGFTSGRHYWEVE 368
Query: 628 VDEHLDYRVGVAFADVRKQEDLGA--NCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVP 685
V + + VGV V ++ +L W +R + KY TP + I V
Sbjct: 369 VGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVR---LWNGDKYAATTTPFTP-LHIKVK 424
Query: 686 PKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726
PK++GI LDYE LSF+NV H+YTF+ E + P F
Sbjct: 425 PKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 465
Score = 51.2 bits (121), Expect = 3e-06
Identities = 40/208 (19%), Positives = 90/208 (43%), Gaps = 7/208 (3%)
Query: 174 EAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENF 233
EA +FC + + + H+ H V+PL++A + K+++ K + LE+++ E+
Sbjct: 112 EALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRC 171
Query: 234 ANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLV 293
+ E+ ++ + Q + E+ L ++ + + L E++++ L+ L
Sbjct: 172 KSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAA 231
Query: 294 SCGENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTK--TDVEISAQPEFED 351
G+ L +E C + + +KD + ++ K +KT T V I + F +
Sbjct: 232 HLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEK-VKTMEVTSVSIELEKNFSN 290
Query: 352 QTLDF----SDVEQLMGSINTIPAPSAP 375
+ ++QL+ + P + P
Sbjct: 291 FPRQYFALRKILKQLIADVTLDPETAHP 318
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 76.3 bits (186), Expect = 1e-13
Identities = 56/161 (34%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +SED + E R R+L + FT V+ G HYWEVE
Sbjct: 341 LDPETAHPNLVLSEDRKSVKFVETRL--RDLPDTPRRFTFYPCVLATEGFTSGRHYWEVE 398
Query: 628 VDEHLDYRVGVAFADVRKQEDLGA--NCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVP 685
V + + VGV V ++ +L W +R + KY TP + I V
Sbjct: 399 VGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVR---LWNGDKYAATTTPFTP-LHIKVK 454
Query: 686 PKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726
PK++GI LDYE LSF+NV H+YTF+ E + P F
Sbjct: 455 PKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 495
Score = 48.1 bits (113), Expect = 3e-05
Identities = 29/157 (18%), Positives = 70/157 (44%)
Query: 174 EAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENF 233
EA +FC + + + H+ H V+PL++A + K+++ K + LE+++ E+
Sbjct: 112 EALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRC 171
Query: 234 ANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLV 293
+ E+ ++ + Q + E+ L ++ + + L E++++ L+ L
Sbjct: 172 KSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAA 231
Query: 294 SCGENLDTCKELMETIEEMCHEEKVDFIKDAVAMADR 330
G+ L +E C + + +KD + ++
Sbjct: 232 HLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEK 268
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 76.3 bits (186), Expect = 1e-13
Identities = 64/275 (23%), Positives = 122/275 (44%), Gaps = 57/275 (20%)
Query: 147 REAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLN 206
+E+ R H +A + C EE EEE +++C++C+ P + KVF HK+ EV PL
Sbjct: 110 QESSRPLHSKAEQHLMC-----EEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLP 164
Query: 207 EALESAKDEIHKNMYKLE--------------------------KQIIEME--------- 231
+ K + + +LE +II+ E
Sbjct: 165 TIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLV 224
Query: 232 -------NFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEK 284
+EEV T+E+N +Q+Q + + L ++ E +QAL +++EK
Sbjct: 225 AGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEK 284
Query: 285 LEALYGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEI 343
L+ + G + G++L+ +L+E+ I+ M + +++ A + +++G K VE+
Sbjct: 285 LQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSK----VEL 340
Query: 344 SAQPE-----FEDQTLDFSDVEQLMGSINTIPAPS 373
+ +PE E T+ V +++ +I+ P S
Sbjct: 341 AGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGAS 375
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 75.9 bits (185), Expect = 1e-13
Identities = 73/309 (23%), Positives = 136/309 (44%), Gaps = 18/309 (5%)
Query: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
E E E ++CV+C+TP+ H +HEV PL + K ++ + + + + E
Sbjct: 305 EHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKE 364
Query: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
+ F L+ + ++EN E + + +++ L ++ + + + ++++ KL+ ++
Sbjct: 365 AKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVW 424
Query: 290 GQLVSCGENLDTCKELMETIEEMCHEEKVD---FIKDAVAMADRLGKFLKTKTDVEISAQ 346
Q+ C L LME E+ E I DA+ ++ + K +E
Sbjct: 425 DQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS 484
Query: 347 PEFEDQTLDFSDVEQLMGSINTIP----APSAPVINPQVPNSAT-GSSVRVCWSL--YSD 399
EF D TLD + Q + ++ I P P++ Q+ T +SV + W + ++
Sbjct: 485 AEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLL--QLEKCCTRNNSVTLAWRMPPFTH 541
Query: 400 DTVESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPS 459
V+ Y L + D + G Q KET C++ L N+ Y V A N +G P
Sbjct: 542 SPVDGYILE---LDDGAGG--QFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPY 596
Query: 460 SERAVYMTA 468
S+ V T+
Sbjct: 597 SKTVVLQTS 605
Score = 63.9 bits (154), Expect = 5e-10
Identities = 73/289 (25%), Positives = 118/289 (40%), Gaps = 37/289 (12%)
Query: 469 PSPPIIKTKEIRSCEEAVLICWESGNL--NPVDSYTVELTQAESPEASGVTESVVGIPTC 526
P P+++ ++ + +V + W +PVD Y +EL + E VG T
Sbjct: 513 PPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILELDDGAGGQ---FREVYVGKETL 569
Query: 527 ESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIG-SYFRLNKDTCHPWLTISEDGLT 585
++ L +Y V+A N G S+ + T ++F + ++ H + +S D T
Sbjct: 570 CTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQT 629
Query: 586 AVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEV---DEHLDYRVGVAFAD 642
A S S D V+G +G HYWE+ V D H D GVA A
Sbjct: 630 ATCS---------SYDDR------VVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARAS 674
Query: 643 VRKQEDLGANCLSWCMRHTFASSRHKYEFLH-----NRTTPDIRITVPPKKIGILLDYEH 697
V K LG + +W M + + + F+H NRT + +G+LLD
Sbjct: 675 VVKDMMLGKDDKAWAM---YVDNNRSW-FMHCNSHTNRTEGGV---CKGATVGVLLDLNK 727
Query: 698 SKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
L+FF Q FS + P SL + + +H G+ +P ++
Sbjct: 728 HTLTFFINGQQQGPTAFS-HVDGVFMPALSLNRNVQVTLHTGLEVPTNL 775
>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
sapiens]
Length = 584
Score = 75.1 bits (183), Expect = 2e-13
Identities = 51/165 (30%), Positives = 82/165 (49%), Gaps = 11/165 (6%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ DT + L +SED + R+E R+L + F V+G G HYWEVE
Sbjct: 344 LDPDTANAILLVSEDQRSVQRAEE---PRDLPDNPERFEWRYCVLGCENFTSGRHYWEVE 400
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
V + ++ +GV +V +++ + W M T +KY L T ++++
Sbjct: 401 VGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLT---DGNKYRALTEPRT-NLKLPE 456
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTF-SCQLHEFVHPCFSL 728
PP+K+GI LDYE ++SF+N H+YTF E ++P F +
Sbjct: 457 PPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRI 501
>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
sapiens]
Length = 542
Score = 75.1 bits (183), Expect = 2e-13
Identities = 51/165 (30%), Positives = 82/165 (49%), Gaps = 11/165 (6%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ DT + L +SED + R+E R+L + F V+G G HYWEVE
Sbjct: 302 LDPDTANAILLVSEDQRSVQRAEE---PRDLPDNPERFEWRYCVLGCENFTSGRHYWEVE 358
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
V + ++ +GV +V +++ + W M T +KY L T ++++
Sbjct: 359 VGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLT---DGNKYRALTEPRT-NLKLPE 414
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTF-SCQLHEFVHPCFSL 728
PP+K+GI LDYE ++SF+N H+YTF E ++P F +
Sbjct: 415 PPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRI 459
>gi|46409324 SPRY domain containing 4 [Homo sapiens]
Length = 207
Score = 73.6 bits (179), Expect = 6e-13
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 5/182 (2%)
Query: 563 GSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHH 622
G F+L + T H L + D +++ + F V+ + G H
Sbjct: 29 GVSFKLEEKTAHSSLALFRDDTGVKYGLVGLEPTKVALNVERFREWAVVLADTAVTSGRH 88
Query: 623 YWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRI 682
YWEV V +R+GVA D+ + +G + SW + + R Y L N P +
Sbjct: 89 YWEVTVKRSQQFRIGVADVDMSRDSCIGVDDRSWVFTY---AQRKWYTMLANEKAP-VEG 144
Query: 683 TVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISM 742
P+K+G+LL+YE KLS +V ++T V P F+L G L H+G+ +
Sbjct: 145 IGQPEKVGLLLEYEAQKLSLVDVSQVSVVHTLQTDFRGPVVPAFAL-WDGELLTHSGLEV 203
Query: 743 PK 744
P+
Sbjct: 204 PE 205
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 73.2 bits (178), Expect = 8e-13
Identities = 43/169 (25%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Query: 169 EEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQII 228
EE EEE +++C+ C+ P + KVF HK+ +V PL + K E+ + L
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSND 184
Query: 229 EMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEAL 288
++ + LE+ T+EE KQ+Q ++ + L ++ E Q + ++EKLE +
Sbjct: 185 RVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHV 244
Query: 289 YGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAVAMADRLGKFLK 336
+ ++L+ +L+E+ I+ M E F+++A + ++ + K
Sbjct: 245 RALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASK 293
Score = 30.0 bits (66), Expect = 8.2
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 13/209 (6%)
Query: 182 TCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE-----MENFANH 236
TCKT +K E E + L LE K+E+ + + + +++ +E ++ +++H
Sbjct: 196 TCKTIEECCRKQKQELCE-KFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDH 254
Query: 237 LEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCG 296
LE V VE ++ + + + +TL +K E +A + EK+E Y +
Sbjct: 255 LENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAF---QMEKIEHGYENMNHFT 311
Query: 297 ENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVE--ISAQPEFEDQTL 354
NL+ ++++ I+ +E + + + G+ +VE + Q EF +
Sbjct: 312 VNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDE 371
Query: 355 DFSDVEQLMGSINTIPAPSA-PVINPQVP 382
+ +L + AP A PV +P+ P
Sbjct: 372 NPEKASEL-SQVELQAAPGALPVSSPEPP 399
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 73.2 bits (178), Expect = 8e-13
Identities = 43/169 (25%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Query: 169 EEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQII 228
EE EEE +++C+ C+ P + KVF HK+ +V PL + K E+ + L
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSND 184
Query: 229 EMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEAL 288
++ + LE+ T+EE KQ+Q ++ + L ++ E Q + ++EKLE +
Sbjct: 185 RVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHV 244
Query: 289 YGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAVAMADRLGKFLK 336
+ ++L+ +L+E+ I+ M E F+++A + ++ + K
Sbjct: 245 RALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASK 293
Score = 30.0 bits (66), Expect = 8.2
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 13/209 (6%)
Query: 182 TCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE-----MENFANH 236
TCKT +K E E + L LE K+E+ + + + +++ +E ++ +++H
Sbjct: 196 TCKTIEECCRKQKQELCE-KFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDH 254
Query: 237 LEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCG 296
LE V VE ++ + + + +TL +K E +A + EK+E Y +
Sbjct: 255 LENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAF---QMEKIEHGYENMNHFT 311
Query: 297 ENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVE--ISAQPEFEDQTL 354
NL+ ++++ I+ +E + + + G+ +VE + Q EF +
Sbjct: 312 VNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDE 371
Query: 355 DFSDVEQLMGSINTIPAPSA-PVINPQVP 382
+ +L + AP A PV +P+ P
Sbjct: 372 NPEKASEL-SQVELQAAPGALPVSSPEPP 399
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 73.2 bits (178), Expect = 8e-13
Identities = 43/169 (25%), Positives = 84/169 (49%), Gaps = 1/169 (0%)
Query: 169 EEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQII 228
EE EEE +++C+ C+ P + KVF HK+ +V PL + K E+ + L
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSND 184
Query: 229 EMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEAL 288
++ + LE+ T+EE KQ+Q ++ + L ++ E Q + ++EKLE +
Sbjct: 185 RVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHV 244
Query: 289 YGQLVSCGENLDTCKELMET-IEEMCHEEKVDFIKDAVAMADRLGKFLK 336
+ ++L+ +L+E+ I+ M E F+++A + ++ + K
Sbjct: 245 RALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASK 293
Score = 30.0 bits (66), Expect = 8.2
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 13/209 (6%)
Query: 182 TCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE-----MENFANH 236
TCKT +K E E + L LE K+E+ + + + +++ +E ++ +++H
Sbjct: 196 TCKTIEECCRKQKQELCE-KFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDH 254
Query: 237 LEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCG 296
LE V VE ++ + + + +TL +K E +A + EK+E Y +
Sbjct: 255 LENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAF---QMEKIEHGYENMNHFT 311
Query: 297 ENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVE--ISAQPEFEDQTL 354
NL+ ++++ I+ +E + + + G+ +VE + Q EF +
Sbjct: 312 VNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDE 371
Query: 355 DFSDVEQLMGSINTIPAPSA-PVINPQVP 382
+ +L + AP A PV +P+ P
Sbjct: 372 NPEKASEL-SQVELQAAPGALPVSSPEPP 399
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 72.8 bits (177), Expect = 1e-12
Identities = 52/162 (32%), Positives = 79/162 (48%), Gaps = 14/162 (8%)
Query: 557 ATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTH-FTRCVAVMGNL 615
AT+H + L+ DT HP L + ED +S R +R+ P T F V+G
Sbjct: 298 ATLHAVD--VTLDPDTAHPHLFLYEDS----KSVRLEDSRQKLPEKTERFDSWPCVLGRE 351
Query: 616 IPVRGHHYWEVEVDEHLDYRVGVAFADVRKQ--EDLGANCLSWCMRHTFASSRHKYEFLH 673
G HYWEVEV + D+ +GV +V K+ + + W + + Y L
Sbjct: 352 TFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVE----LYGNGYWALT 407
Query: 674 NRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFS 715
TP + + PP+++GI LDYE +SF+N++ +YTFS
Sbjct: 408 PLRTP-LPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFS 448
>gi|229577048 butyrophilin-like 8 isoform 6 [Homo sapiens]
Length = 316
Score = 72.0 bits (175), Expect = 2e-12
Identities = 53/160 (33%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +S+ L V + R+ P +E+ S+ FTR V G HYWEV+
Sbjct: 108 LDPETAHPKLCVSD--LKTV-THRKAP-QEVPHSEKRFTRKSVVASQSFQA-GKHYWEVD 162
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
+ +RVGV DV ++++ L + W +R + H Y L+ R T
Sbjct: 163 GGHNKRWRVGVCRDDVDRRKEYVTLSPDHGYWVLR---LNGEHLYFTLNPRFISVFPRT- 218
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHP 724
PP KIG+ LDYE +SFFN++ +YT +C+ + P
Sbjct: 219 PPTKIGVFLDYECGTISFFNINDQSLIYTLTCRFEGLLRP 258
>gi|229577043 butyrophilin-like 8 isoform 5 [Homo sapiens]
Length = 375
Score = 72.0 bits (175), Expect = 2e-12
Identities = 53/160 (33%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +S+ L V + R+ P +E+ S+ FTR V G HYWEV+
Sbjct: 167 LDPETAHPKLCVSD--LKTV-THRKAP-QEVPHSEKRFTRKSVVASQSFQA-GKHYWEVD 221
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
+ +RVGV DV ++++ L + W +R + H Y L+ R T
Sbjct: 222 GGHNKRWRVGVCRDDVDRRKEYVTLSPDHGYWVLR---LNGEHLYFTLNPRFISVFPRT- 277
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHP 724
PP KIG+ LDYE +SFFN++ +YT +C+ + P
Sbjct: 278 PPTKIGVFLDYECGTISFFNINDQSLIYTLTCRFEGLLRP 317
>gi|229577033 butyrophilin-like 8 isoform 3 precursor [Homo sapiens]
Length = 384
Score = 72.0 bits (175), Expect = 2e-12
Identities = 53/160 (33%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +S+ L V + R+ P +E+ S+ FTR V G HYWEV+
Sbjct: 176 LDPETAHPKLCVSD--LKTV-THRKAP-QEVPHSEKRFTRKSVVASQSFQA-GKHYWEVD 230
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
+ +RVGV DV ++++ L + W +R + H Y L+ R T
Sbjct: 231 GGHNKRWRVGVCRDDVDRRKEYVTLSPDHGYWVLR---LNGEHLYFTLNPRFISVFPRT- 286
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHP 724
PP KIG+ LDYE +SFFN++ +YT +C+ + P
Sbjct: 287 PPTKIGVFLDYECGTISFFNINDQSLIYTLTCRFEGLLRP 326
>gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]
Length = 500
Score = 72.0 bits (175), Expect = 2e-12
Identities = 53/160 (33%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ +T HP L +S+ L V + R+ P +E+ S+ FTR V G HYWEV+
Sbjct: 292 LDPETAHPKLCVSD--LKTV-THRKAP-QEVPHSEKRFTRKSVVASQSFQA-GKHYWEVD 346
Query: 628 VDEHLDYRVGVAFADVRKQED---LGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITV 684
+ +RVGV DV ++++ L + W +R + H Y L+ R T
Sbjct: 347 GGHNKRWRVGVCRDDVDRRKEYVTLSPDHGYWVLR---LNGEHLYFTLNPRFISVFPRT- 402
Query: 685 PPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHP 724
PP KIG+ LDYE +SFFN++ +YT +C+ + P
Sbjct: 403 PPTKIGVFLDYECGTISFFNINDQSLIYTLTCRFEGLLRP 442
>gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Homo
sapiens]
Length = 461
Score = 72.0 bits (175), Expect = 2e-12
Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 568 LNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVE 627
L+ T +P L +SED + R++ ++L + F V+G + G HYWEVE
Sbjct: 292 LDPKTANPILLVSEDQRSVQRAKE---PQDLPDNPERFNWHYCVLGCESFISGRHYWEVE 348
Query: 628 VDEHLDYRVGVAFADVRKQEDLGANCLS--WCMRHTFASSRHKYEFLHNRTTPDIRITVP 685
V + ++ +GV +V+++ + + W M T +KY L T ++++ P
Sbjct: 349 VGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLT---DGNKYRTLTEPRT-NLKLPKP 404
Query: 686 PKKIGILLDYEHSKLSFFNVDLSQHLYTF-SCQLHEFVHPCFSL 728
PKK+G+ LDYE +SF+N H++TF E ++P F +
Sbjct: 405 PKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRI 448
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,268,423
Number of Sequences: 37866
Number of extensions: 1514806
Number of successful extensions: 6815
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 368
Number of HSP's that attempted gapping in prelim test: 5361
Number of HSP's gapped (non-prelim): 1544
length of query: 749
length of database: 18,247,518
effective HSP length: 110
effective length of query: 639
effective length of database: 14,082,258
effective search space: 8998562862
effective search space used: 8998562862
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.