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Search of human proteins with 54792780
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792780 DDHD domain containing 2 [Homo sapiens]
(711 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792780 DDHD domain containing 2 [Homo sapiens] 1454 0.0
gi|6005824 Sec23-interacting protein p125 [Homo sapiens] 754 0.0
gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens] 115 1e-25
gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens] 115 1e-25
gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens] 113 7e-25
gi|190358515 PITPNM family member 3 [Homo sapiens] 81 3e-15
gi|195927015 phosphatidylinositol transfer protein, membrane-ass... 68 3e-11
gi|195927017 phosphatidylinositol transfer protein, membrane-ass... 68 3e-11
gi|148664246 harmonin-interacting ankyrin-repeat containing prot... 62 1e-09
gi|34304383 Usher syndrome 1G protein [Homo sapiens] 61 4e-09
gi|67906195 ankyrin repeat and sterile alpha motif domain contai... 45 2e-04
gi|24308237 phosphatidylinositol transfer protein, membrane-asso... 44 7e-04
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 40 0.006
gi|42734375 ankyrin repeat and sterile alpha motif domain contai... 34 0.41
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 33 0.70
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 32 2.7
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 31 3.5
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 31 3.5
gi|7662018 PHD finger protein 3 [Homo sapiens] 30 5.9
gi|42544241 iroquois homeobox protein 6 [Homo sapiens] 30 5.9
gi|110349719 titin isoform N2-A [Homo sapiens] 30 7.7
gi|38261962 activating transcription factor 7 interacting protei... 30 7.7
gi|148612801 KIAA1009 protein [Homo sapiens] 30 7.7
>gi|54792780 DDHD domain containing 2 [Homo sapiens]
Length = 711
Score = 1454 bits (3764), Expect = 0.0
Identities = 711/711 (100%), Positives = 711/711 (100%)
Query: 1 MSSVQSQQEQLSQSDPSPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFN 60
MSSVQSQQEQLSQSDPSPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFN
Sbjct: 1 MSSVQSQQEQLSQSDPSPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFN 60
Query: 61 SEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKGD 120
SEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKGD
Sbjct: 61 SEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKGD 120
Query: 121 KDNKYVPYSESSSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDG 180
KDNKYVPYSESSSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDG
Sbjct: 121 KDNKYVPYSESSSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDG 180
Query: 181 WGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVND 240
WGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVND
Sbjct: 181 WGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVND 240
Query: 241 FRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFT 300
FRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFT
Sbjct: 241 FRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFT 300
Query: 301 NDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDI 360
NDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDI
Sbjct: 301 NDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLILFDI 360
Query: 361 LTNQKDSLGDIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCT 420
LTNQKDSLGDIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCT
Sbjct: 361 LTNQKDSLGDIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCT 420
Query: 421 DRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDY 480
DRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDY
Sbjct: 421 DRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDY 480
Query: 481 LDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPF 540
LDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPF
Sbjct: 481 LDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPF 540
Query: 541 DPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKS 600
DPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKS
Sbjct: 541 DPVAYRIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKS 600
Query: 601 FTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQRID 660
FTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQRID
Sbjct: 601 FTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQRID 660
Query: 661 YVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ 711
YVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ
Sbjct: 661 YVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQPLQ 711
>gi|6005824 Sec23-interacting protein p125 [Homo sapiens]
Length = 1000
Score = 754 bits (1947), Expect = 0.0
Identities = 403/772 (52%), Positives = 520/772 (67%), Gaps = 72/772 (9%)
Query: 2 SSVQSQQEQLSQSDP-SPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFN 60
SSVQS +Q + P +PS S F L + YEPV PHWFYCK ++ K+ W+PF+
Sbjct: 235 SSVQSPAQQQVPARPGAPSVQVPSPFLLQNQ-----YEPVQPHWFYCKEVEYKQLWMPFS 289
Query: 61 SEDSQQLEEAYSSGKGCNGRVV-PTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKG 119
DS LEE Y+S + VV TDGGRYDV+L +R+R A YW+E +EVRRCTWFYKG
Sbjct: 290 VFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKG 349
Query: 120 DKDNKYVPYSESSSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSD 179
D D++++PY+E S+ LE Y AVT ++W ++LE P+ E I++HNPK++V +QP + D
Sbjct: 350 DTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPD 409
Query: 180 GWGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVN 239
WG+T Q RPR VKRG+++ +I GE Q+DHLVFVVHGIGP CDLRFRSI++CV+
Sbjct: 410 EWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVD 469
Query: 240 DFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPL--HSTGVDVDLQRITLPSINRLR 297
DFR VSL LL+THFKK+ ++ ++ RVEFLPV+WHS L +TGVD ++++ITLPSI R R
Sbjct: 470 DFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFR 529
Query: 298 HFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLIL 357
HFTN+T+LD+ FYNSPTYCQTIV+ V E+N ++ LF+ RNPDFKGGVS+AGHSLGSLIL
Sbjct: 530 HFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLIL 589
Query: 358 FDILTNQKD------------SLGDID----SEK-----------DSLNIVMYQGDTPTL 390
FDIL+NQKD + G + EK +S ++V+ + TL
Sbjct: 590 FDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTL 649
Query: 391 EEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTR------ 444
+E L+ L LSE+F FEKEK+D E+L +CT DL+E+GIPLGPRKKI N+ +
Sbjct: 650 QETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKK 709
Query: 445 ----------KNSMGIKRPAPQPASGANIPKESE---------FCSSSNTRNGDYLDVGI 485
++ G ++ A + A++P ES C SS N + +VG
Sbjct: 710 AASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGA 769
Query: 486 GQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPFDPVAY 545
GQVSV Y L ++PEIFFA GSPI MFLT+RG+ RID NY PTCKGFFNIYHP DPVAY
Sbjct: 770 GQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAY 829
Query: 546 RIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKS---FT 602
R+EPM+VP ++ + +LIPHHKGRKR+HLEL+E L+RM DLK + SL+ AW++ F
Sbjct: 830 RLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFA 889
Query: 603 RAPYPALQASETPEET-----EAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQ 657
RA + Q E E+ E E + E V + + S K+E VGMLNGG+
Sbjct: 890 RAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKVVESPDFS---KDEDYLGKVGMLNGGR 946
Query: 658 RIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQP 709
RIDYVLQEKPIESFNEYLFALQSHLCYWESEDT LL+LKEIY+T I +QP
Sbjct: 947 RIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQP 998
>gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens]
Length = 900
Score = 115 bits (289), Expect = 1e-25
Identities = 94/301 (31%), Positives = 139/301 (46%), Gaps = 37/301 (12%)
Query: 86 GGRYDVHLGERMRYAVYWDELAS-EVRRCTWFYKGDKDNKYVPYSESSSQVLEETYMLAV 144
GG Y+V + + Y VYW++ V R WF D + P E S ++E+ ++
Sbjct: 261 GGLYEVDVTQGECYPVYWNQADKIPVMRGQWFI----DGTWQPLEEEESNLIEQEHLNCF 316
Query: 145 TLDEWKKKLESPNREII----ILHNPKLMVHYQPVAGSDGW----GSTPTEQGRPRTVKR 196
+ ++ + + I +H+ KL ++ D +T ++ R T K
Sbjct: 317 RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKL 376
Query: 197 GVENISVD---IHCG---------EPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSV 244
G S +H G +P Q H+VFVVHGIG D I++ R
Sbjct: 377 GFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQG--RIIKNTAMMREA 434
Query: 245 SLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNDTI 304
+ + + HF + VEFLPV W S L G VD IT + LR N +
Sbjct: 435 ARKIEERHF-----SNHATHVEFLPVEWRSKLTLDGDTVD--SITPDKVRGLRDMLNSSA 487
Query: 305 LDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGSLILFDIL 361
+D+ +Y SP Y +V + E+NR+Y+LF RNPDF KGG VSI HSLG +I +DI+
Sbjct: 488 MDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIM 547
Query: 362 T 362
T
Sbjct: 548 T 548
Score = 61.6 bits (148), Expect = 2e-09
Identities = 66/282 (23%), Positives = 113/282 (40%), Gaps = 78/282 (27%)
Query: 493 PRLIYKPEIFFAFGSPIGMFLTVRGLKRIDP---NYRFPT--CKGFFNIYHPFDPVAYRI 547
P L +K E FF GSP+ +FL +RG++ + ++ P C NI+HP DPVAYR+
Sbjct: 609 PALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRL 668
Query: 548 EPMVVPGVE------------FEPMLIPHHK------GRKRMHLELREGLTRMSMDL--- 586
EP+++ P+ H K ++ + EG++ + +
Sbjct: 669 EPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSP 728
Query: 587 ---------------KNNLLGSLR-------MAWKSFTRAPYPALQASETPEETEAEPES 624
K ++LG+ M + F R+ Q+SET +++ + +
Sbjct: 729 VLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRS--STTQSSETSKDSMEDEKK 786
Query: 625 TSEKPSDVNT--------------------EETSVAVKEEVLPINV------GMLNGGQR 658
PS +E+ + + + P NV ++ R
Sbjct: 787 PVASPSATTVGTQTLPHSSSGFLDSAYFRLQESFFNLPQLLFPENVMQNKDNALVELDHR 846
Query: 659 IDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQ 700
ID+ L+E +ES Y A+ SH YW S D L +L +Y+
Sbjct: 847 IDFELREGLVES--RYWSAVTSHTAYWSSLDVALFLLTFMYK 886
>gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens]
Length = 872
Score = 115 bits (289), Expect = 1e-25
Identities = 94/301 (31%), Positives = 139/301 (46%), Gaps = 37/301 (12%)
Query: 86 GGRYDVHLGERMRYAVYWDELAS-EVRRCTWFYKGDKDNKYVPYSESSSQVLEETYMLAV 144
GG Y+V + + Y VYW++ V R WF D + P E S ++E+ ++
Sbjct: 261 GGLYEVDVTQGECYPVYWNQADKIPVMRGQWFI----DGTWQPLEEEESNLIEQEHLNCF 316
Query: 145 TLDEWKKKLESPNREII----ILHNPKLMVHYQPVAGSDGW----GSTPTEQGRPRTVKR 196
+ ++ + + I +H+ KL ++ D +T ++ R T K
Sbjct: 317 RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKL 376
Query: 197 GVENISVD---IHCG---------EPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSV 244
G S +H G +P Q H+VFVVHGIG D I++ R
Sbjct: 377 GFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQG--RIIKNTAMMREA 434
Query: 245 SLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLRHFTNDTI 304
+ + + HF + VEFLPV W S L G VD IT + LR N +
Sbjct: 435 ARKIEERHF-----SNHATHVEFLPVEWRSKLTLDGDTVD--SITPDKVRGLRDMLNSSA 487
Query: 305 LDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGSLILFDIL 361
+D+ +Y SP Y +V + E+NR+Y+LF RNPDF KGG VSI HSLG +I +DI+
Sbjct: 488 MDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIM 547
Query: 362 T 362
T
Sbjct: 548 T 548
Score = 68.9 bits (167), Expect = 2e-11
Identities = 61/253 (24%), Positives = 106/253 (41%), Gaps = 48/253 (18%)
Query: 493 PRLIYKPEIFFAFGSPIGMFLTVRGLKRIDP---NYRFPT--CKGFFNIYHPFDPVAYRI 547
P L +K E FF GSP+ +FL +RG++ + ++ P C NI+HP DPVAYR+
Sbjct: 609 PALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRL 668
Query: 548 EPMVVPGVE------------FEPMLIPHHK------GRKRMHLELREGLTRMSMDL--- 586
EP+++ P+ H K ++ + EG++ + +
Sbjct: 669 EPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSP 728
Query: 587 ---------------KNNLLGSLRMAWKSFTRAPYPALQASETPEETEAEPESTSEKPSD 631
K ++LG+ + K + S T + +E +S ++
Sbjct: 729 VLSRRHYGESITNIGKASILGAASIG-KGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKP 787
Query: 632 VNTEETSVAVKEEVLPINVGMLNGG----QRIDYVLQEKPIESFNEYLFALQSHLCYWES 687
V + + + + + G L+ RID+ L+E +ES Y A+ SH YW S
Sbjct: 788 VASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVES--RYWSAVTSHTAYWSS 845
Query: 688 EDTVLLVLKEIYQ 700
D L +L +Y+
Sbjct: 846 LDVALFLLTFMYK 858
>gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens]
Length = 879
Score = 113 bits (282), Expect = 7e-25
Identities = 94/308 (30%), Positives = 139/308 (45%), Gaps = 44/308 (14%)
Query: 86 GGRYDVHLGERMRYAVYWDELAS-EVRRCTWFYKGDKDNKYVPYSESSSQVLEETYMLAV 144
GG Y+V + + Y VYW++ V R WF D + P E S ++E+ ++
Sbjct: 261 GGLYEVDVTQGECYPVYWNQADKIPVMRGQWFI----DGTWQPLEEEESNLIEQEHLNCF 316
Query: 145 TLDEWKKKLESPNREII-----------ILHNPKLMVHYQPVAGSDGW----GSTPTEQG 189
+ ++ + + I +H+ KL ++ D +T ++
Sbjct: 317 RGQQMQENFDIEVSKSIDGKDGSGINYSAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIA 376
Query: 190 RPRTVKRGVENISVD---IHCG---------EPLQIDHLVFVVHGIGPACDLRFRSIVQC 237
R T K G S +H G +P Q H+VFVVHGIG D I++
Sbjct: 377 RTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQG--RIIKN 434
Query: 238 VNDFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINRLR 297
R + + + HF + VEFLPV W S L G VD IT + LR
Sbjct: 435 TAMMREAARKIEERHF-----SNHATHVEFLPVEWRSKLTLDGDTVD--SITPDKVRGLR 487
Query: 298 HFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGS 354
N + +D+ +Y SP Y +V + E+NR+Y+LF RNPDF KGG VSI HSLG
Sbjct: 488 DMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGC 547
Query: 355 LILFDILT 362
+I +DI+T
Sbjct: 548 VITYDIMT 555
Score = 68.9 bits (167), Expect = 2e-11
Identities = 61/253 (24%), Positives = 106/253 (41%), Gaps = 48/253 (18%)
Query: 493 PRLIYKPEIFFAFGSPIGMFLTVRGLKRIDP---NYRFPT--CKGFFNIYHPFDPVAYRI 547
P L +K E FF GSP+ +FL +RG++ + ++ P C NI+HP DPVAYR+
Sbjct: 616 PALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRL 675
Query: 548 EPMVVPGVE------------FEPMLIPHHK------GRKRMHLELREGLTRMSMDL--- 586
EP+++ P+ H K ++ + EG++ + +
Sbjct: 676 EPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSP 735
Query: 587 ---------------KNNLLGSLRMAWKSFTRAPYPALQASETPEETEAEPESTSEKPSD 631
K ++LG+ + K + S T + +E +S ++
Sbjct: 736 VLSRRHYGESITNIGKASILGAASIG-KGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKP 794
Query: 632 VNTEETSVAVKEEVLPINVGMLNGG----QRIDYVLQEKPIESFNEYLFALQSHLCYWES 687
V + + + + + G L+ RID+ L+E +ES Y A+ SH YW S
Sbjct: 795 VASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVES--RYWSAVTSHTAYWSS 852
Query: 688 EDTVLLVLKEIYQ 700
D L +L +Y+
Sbjct: 853 LDVALFLLTFMYK 865
>gi|190358515 PITPNM family member 3 [Homo sapiens]
Length = 974
Score = 81.3 bits (199), Expect = 3e-15
Identities = 96/412 (23%), Positives = 172/412 (41%), Gaps = 44/412 (10%)
Query: 305 LDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPD--FKGGVSIAGHSLGSLILFDILT 362
L + +SP Y Q V TV N++Y FL+ + F G V + G +G L+ FD +
Sbjct: 219 LPLLAISSPQY-QDAVATVIERANQVYREFLKSSDGIGFSGQVCLIGDCVGGLLAFDAIC 277
Query: 363 NQKDSLGDIDSEKDSLNIVMYQGDTPT-LEEDLKKLQLSEFFDIFEKEKVDKEALALCTD 421
GD + + DTP +EED + +++ K + + +
Sbjct: 278 YSAGPSGDSPASSSRKGSISSTQDTPVAVEEDCS---------LASSKRLSKSNIDISSG 328
Query: 422 RDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDYL 481
+ +E PL PRK+ + ST + A + +++ K+ S + G L
Sbjct: 329 LEDEEPKRPL-PRKQ--SDSSTYDCEAITQHHAFLSSIHSSVLKDE---SETPAAGGPQL 382
Query: 482 -DVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRG--LKRIDPNYRFPTCKGFFNIYH 538
+V +G R + FF FGSP+G+ L +R L +D P C ++ +H
Sbjct: 383 PEVSLG-------RFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFH 435
Query: 539 PFDPVAYRIEPMVVPGVEF-EPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMA 597
DP A R+EP++ P P+ +P ++ L +G S+ L + L +
Sbjct: 436 CADPSASRLEPLLEPKFHLVPPVSVPRYQ-----RFPLGDG---QSLLLADALHTHSPLF 487
Query: 598 WKSFTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLN--- 654
+ +R P L A +P + + + + S+ ++ S + + P+ +
Sbjct: 488 LEGSSRDSPPLLDAPASPPQA-SRFQRPGRRMSEGSSHSESSESSDSMAPVGASRITAKW 546
Query: 655 -GGQRIDYVLQ-EKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGI 704
G +RIDY L + +F H YWES D V +L+++ + + +
Sbjct: 547 WGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESV 598
>gi|195927015 phosphatidylinositol transfer protein,
membrane-associated isoform a [Homo sapiens]
Length = 1244
Score = 68.2 bits (165), Expect = 3e-11
Identities = 95/405 (23%), Positives = 161/405 (39%), Gaps = 70/405 (17%)
Query: 317 QTIVDTVASEMNRIYTLFLQRNPD---FKGGVSIAGHSLGSLILFDILTNQKD----SLG 369
Q V TV + N+ Y+ FL R+P+ F G V++ G +G ++ FD L + + S G
Sbjct: 529 QGAVATVIARTNQAYSAFL-RSPEGAGFCGQVALIGDGVGGILGFDALCHSANAGTGSRG 587
Query: 370 DIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGI 429
S + S+N + + + + L + + E AL R ++
Sbjct: 588 S--SRRGSMNNELLSPEFGPVRDPLAD-------GVEGLGRGSPEPSALPPQRIPSDMAS 638
Query: 430 PLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESE-FC---SSSNTRNGDYLDVGI 485
P + S + AP S + S FC +SS +G
Sbjct: 639 P------------EPEGSQNSLQAAPATTSSWEPRRASTAFCPPAASSEAPDGPSSTA-- 684
Query: 486 GQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRG--LKRIDPNYRFPTCKGFFNIYHPFDPV 543
RL +K FF FGSP+G+ L +R + ++ P C+ +N++H DP
Sbjct: 685 --------RLDFKVSGFFLFGSPLGLVLALRKTVMPALEAAQMRPACEQIYNLFHAADPC 736
Query: 544 AYRIEPMVVPGVE-FEPMLIPHHKGRKRMHLELREGLTRMSMDL----KNNLLGSLRMAW 598
A R+EP++ P + P+ +P ++ L +G + + D + L L M
Sbjct: 737 ASRLEPLLAPKFQAIAPLTVPRYQ-----KFPLGDGSSLLLADTLQTHSSLFLEELEMLV 791
Query: 599 KSFTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQR 658
S TP T SE +D + + + EV+ I + G +R
Sbjct: 792 PS-------------TPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKI-LERWWGTKR 837
Query: 659 IDYVLQ-EKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQ 702
IDY L + + +F H YWES D V +L+++ + +
Sbjct: 838 IDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKE 882
>gi|195927017 phosphatidylinositol transfer protein,
membrane-associated isoform b [Homo sapiens]
Length = 1243
Score = 67.8 bits (164), Expect = 3e-11
Identities = 96/405 (23%), Positives = 162/405 (40%), Gaps = 71/405 (17%)
Query: 317 QTIVDTVASEMNRIYTLFLQRNPD---FKGGVSIAGHSLGSLILFDILTNQKD----SLG 369
Q V TV + N+ Y+ FL R+P+ F G V++ G +G ++ FD L + + S G
Sbjct: 529 QGAVATVIARTNQAYSAFL-RSPEGAGFCGQVALIGDGVGGILGFDALCHSANAGTGSRG 587
Query: 370 DIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGI 429
S + S+N + + + + L + + E AL R ++
Sbjct: 588 S--SRRGSMNNELLSPEFGPVRDPLAD-------GVEGLGRGSPEPSALPPQRIPSDMAS 638
Query: 430 PLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESE-FC---SSSNTRNGDYLDVGI 485
P + S + AP S + S FC +SS +G
Sbjct: 639 P------------EPEGSQNSLQAAPATTSSWEPRRASTAFCPPAASSEAPDGPSSTA-- 684
Query: 486 GQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRG--LKRIDPNYRFPTCKGFFNIYHPFDPV 543
RL +K FF FGSP+G+ L +R + ++ R P C+ +N++H DP
Sbjct: 685 --------RLDFKVSGFFLFGSPLGLVLALRKTVMPALEAQMR-PACEQIYNLFHAADPC 735
Query: 544 AYRIEPMVVPGVE-FEPMLIPHHKGRKRMHLELREGLTRMSMDL----KNNLLGSLRMAW 598
A R+EP++ P + P+ +P ++ L +G + + D + L L M
Sbjct: 736 ASRLEPLLAPKFQAIAPLTVPRYQ-----KFPLGDGSSLLLADTLQTHSSLFLEELEMLV 790
Query: 599 KSFTRAPYPALQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQR 658
S TP T SE +D + + + EV+ I + G +R
Sbjct: 791 PS-------------TPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKI-LERWWGTKR 836
Query: 659 IDYVLQ-EKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQ 702
IDY L + + +F H YWES D V +L+++ + +
Sbjct: 837 IDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKE 881
>gi|148664246 harmonin-interacting ankyrin-repeat containing protein
[Homo sapiens]
Length = 417
Score = 62.4 bits (150), Expect = 1e-09
Identities = 31/60 (51%), Positives = 39/60 (65%)
Query: 386 DTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTRK 445
D LE L L EF IF++E++D EAL LC+D DLQ I + LGPRKK+LN + RK
Sbjct: 344 DATPLEVFLLSQHLEEFLPIFKREQIDLEALLLCSDEDLQSIQMQLGPRKKVLNAINRRK 403
>gi|34304383 Usher syndrome 1G protein [Homo sapiens]
Length = 461
Score = 60.8 bits (146), Expect = 4e-09
Identities = 29/63 (46%), Positives = 40/63 (63%)
Query: 386 DTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTRK 445
+T LE L L + +F + +EK+D EAL LC+D DL+ I +PLGPRKKIL R+
Sbjct: 388 ETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRR 447
Query: 446 NSM 448
+M
Sbjct: 448 QAM 450
>gi|67906195 ankyrin repeat and sterile alpha motif domain
containing 6 [Homo sapiens]
Length = 871
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/92 (39%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 386 DTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPL-GPRKKILNYFSTR 444
D L LKKL L ++ IFE+++VD EA TD DL+E+GI G R++IL S
Sbjct: 774 DEDELTGILKKLSLEKYQPIFEEQEVDMEAFLTLTDGDLKELGIKTDGSRQQILAAISEL 833
Query: 445 KNSMGIKRPAPQPASGANIPKESEFCSSSNTR 476
G +R Q N E S+SNTR
Sbjct: 834 NAGKGRERQILQETI-HNFHSSFE-SSASNTR 863
>gi|24308237 phosphatidylinositol transfer protein,
membrane-associated 2 [Homo sapiens]
Length = 1349
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/244 (21%), Positives = 92/244 (37%), Gaps = 53/244 (21%)
Query: 503 FAFGSPIGMFLTVRG--LKRIDPNYRFPTCKGFFNIYHPFDPVAYRIEPMVVPGVE-FEP 559
F FG P+G+ L +R + +D P C+ +N++HP DP A R+EP++ P
Sbjct: 723 FLFGCPLGLVLALRKTVIPALDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHALPP 782
Query: 560 MLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLR-----------MAWKSFTRAPYPA 608
+P ++ L +G + + D+ + + A + F RA +
Sbjct: 783 FSVPRYQ-----RYPLGDGCSTLLADVLQTHNAAFQEHGAPSSPGTAPASRGFRRASEIS 837
Query: 609 L--QASETPEETEAE------PESTSEKPSDVNTEETSVAVKEEVLP------------- 647
+ Q S E A P++ S PS ++ P
Sbjct: 838 IASQVSGMAESYTASSIAQKAPDALSHTPSVRRLSLLALPAPSPTTPGPHPPARKASPGL 897
Query: 648 --------INVGMLN----GGQRIDYVLQ-EKPIESFNEYLFALQSHLCYWESEDTVLLV 694
+++G + G +RIDY L + +F H YWES D V +
Sbjct: 898 ERAPGLPELDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFL 957
Query: 695 LKEI 698
L+++
Sbjct: 958 LRQV 961
Score = 30.4 bits (67), Expect = 5.9
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 3/76 (3%)
Query: 311 NSPTYCQTIVDTVASEMNRIYTLFL--QRNPDFKGGVSIAGHSLGSLILFDILTNQKDSL 368
+SP Y Q V TV N Y F+ Q F G V + G +G ++ FD L +
Sbjct: 520 SSPQY-QEAVATVIQRANLAYGDFIKSQEGMTFNGQVCLIGDCVGGILAFDALCYSNQPV 578
Query: 369 GDIDSEKDSLNIVMYQ 384
+ S ++V Q
Sbjct: 579 SESQSSSRRGSVVSMQ 594
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 40.4 bits (93), Expect = 0.006
Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 390 LEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGI-PLGPRKKIL 438
L E KL L ++ D+F+++++D + TD+DL+E+GI G R+K+L
Sbjct: 878 LPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKML 927
>gi|42734375 ankyrin repeat and sterile alpha motif domain
containing 3 [Homo sapiens]
Length = 656
Score = 34.3 bits (77), Expect = 0.41
Identities = 16/45 (35%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 394 LKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPL-GPRKKI 437
L+++ ++ +FE++ VD T+ DL+EIGI L GP++K+
Sbjct: 434 LEQIGCLKYLQVFEEQDVDLRIFLTLTESDLKEIGITLFGPKRKM 478
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 33.5 bits (75), Expect = 0.70
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%)
Query: 586 LKNNLLGSLRMAWKSFTRAPYPALQASETPEETEAEPESTS-------EKPSDVNTEETS 638
LKN LGSL A + T A P E + E EP S S EK + + EET
Sbjct: 330 LKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETE 389
Query: 639 VAVKEE 644
+ V E+
Sbjct: 390 LGVMED 395
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 31.6 bits (70), Expect = 2.7
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 390 LEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGI-PLGPRKKIL 438
+ + LK L L DIFE E++ + LA +L+EIGI G R K++
Sbjct: 1031 ISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLI 1080
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 31.2 bits (69), Expect = 3.5
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 350 HSLGSLILFDILTN--QKDSLG-DIDSEKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIF 406
HS+ L+ + + Q++S G D D KDS D +E L+KL+ SEFF++
Sbjct: 686 HSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE----DNEVQDEFLEKLETSEFFELT 741
Query: 407 EKEKVDKEALALC 419
+EK+ + ALC
Sbjct: 742 SEEKL-QILTALC 753
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 31.2 bits (69), Expect = 3.5
Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 389 TLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGI-PLGPRKKIL 438
++ + ++ L L DIFE+E++ + L ++L+EIGI G R K++
Sbjct: 877 SITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLI 927
>gi|7662018 PHD finger protein 3 [Homo sapiens]
Length = 2039
Score = 30.4 bits (67), Expect = 5.9
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 58 PFNSEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFY 117
P+ +D QQL+ ++ GKG R D H +R R+ W++ + RR
Sbjct: 1900 PWGRQDQQQLDRPFNRGKGDRQRFYS------DSHHLKRERHEKEWEQESERHRRRDRSQ 1953
Query: 118 KGDKDNK 124
D+D K
Sbjct: 1954 DKDRDRK 1960
>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
Length = 446
Score = 30.4 bits (67), Expect = 5.9
Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 24/167 (14%)
Query: 374 EKDSLNIVMYQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGP 433
E+DSL + T ++ + L+LS+ D+ E+E+ ++EA + +E+ G
Sbjct: 228 EEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEEEEA-------EDEEVVATAGD 280
Query: 434 RKKILNYFSTRKNSMGIKRPAPQPASGANIPKES-------EFCSSSNTRNGDYL--DVG 484
R L F RK + + P G +E F S + D+L + G
Sbjct: 281 R---LTEF--RKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEEADFLSAETG 335
Query: 485 IGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCK 531
++++ YP + KP I+ + V G P R P C+
Sbjct: 336 SPRLTMHYP-CLEKPRIWSLAHTATAS--AVEGAPPARPRPRSPECR 379
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 30.0 bits (66), Expect = 7.7
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 604 APYPALQASET------PEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINV 650
AP P ++ T P++ EA P E P V + + +EEVLP+ V
Sbjct: 10185 APVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEV 10237
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 30.0 bits (66), Expect = 7.7
Identities = 22/98 (22%), Positives = 40/98 (40%), Gaps = 13/98 (13%)
Query: 609 LQASETPEETEAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGG------------ 656
+ + E P++ + T + SD E VKEE+L +V +LNG
Sbjct: 1 MDSLEEPQKKVFKARKTM-RVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPL 59
Query: 657 QRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLV 694
+ +DY+ ++ + E F + W+ +L V
Sbjct: 60 ENMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSV 97
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 30.0 bits (66), Expect = 7.7
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 372 DSEKDSLNIVMYQGDTPTLEEDLKKLQLSEF-FDIFEKEKVDKEALALCTDRDLQEIGIP 430
++E++S NI + D PT+EE +K +++ F F+ + V E +A + + +P
Sbjct: 329 ENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFS-SLP 387
Query: 431 LGPRKKILNYFSTRKN 446
L IL+ S N
Sbjct: 388 LKMNPNILSQDSQHVN 403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,851,365
Number of Sequences: 37866
Number of extensions: 1395915
Number of successful extensions: 4012
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3947
Number of HSP's gapped (non-prelim): 50
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.