Guide to the Human Genome
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Search of human proteins with 5454112

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5454112 transcription factor Dp-2 (E2F dimerization partner
2) [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5454112 transcription factor Dp-2 (E2F dimerization partner 2...   764   0.0  
gi|6005900 transcription factor Dp-1 [Homo sapiens]                   437   e-123
gi|189409125 transcription factor Dp family, member 3 [Homo sapi...   330   2e-90
gi|12669915 E2F transcription factor 4 [Homo sapiens]                  43   4e-04
gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]       39   0.008
gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]       39   0.008
gi|4503433 E2F transcription factor 3 [Homo sapiens]                   37   0.023
gi|12669911 E2F transcription factor 1 [Homo sapiens]                  34   0.25 
gi|44890059 involucrin [Homo sapiens]                                  34   0.25 
gi|145580626 E2F transcription factor 7 [Homo sapiens]                 34   0.25 
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    34   0.25 
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    34   0.25 
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    34   0.25 
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    34   0.25 
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    33   0.33 
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    33   0.43 
gi|38505226 E2F family member 8 [Homo sapiens]                         33   0.57 
gi|171184451 centrosome-associated protein 350 [Homo sapiens]          33   0.57 
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s...    33   0.57 
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          32   0.74 
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          32   0.74 
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]         32   0.74 
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          32   0.74 
gi|4758226 E2F transcription factor 2 [Homo sapiens]                   32   0.74 
gi|109637795 E2F transcription factor 6 [Homo sapiens]                 32   0.74 
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        32   0.74 
gi|18093112 ABT1-associated protein [Homo sapiens]                     32   0.74 
gi|164419758 bromodomain containing 2 [Homo sapiens]                   32   0.97 
gi|4826806 bromodomain containing 2 [Homo sapiens]                     32   0.97 
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap...    32   0.97 

>gi|5454112 transcription factor Dp-2 (E2F dimerization partner 2)
           [Homo sapiens]
          Length = 386

 Score =  764 bits (1973), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR 60
           MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR
Sbjct: 1   MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR 60

Query: 61  SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNI 120
           SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNI
Sbjct: 61  SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNI 120

Query: 121 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE 180
           RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE
Sbjct: 121 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE 180

Query: 181 LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF 240
           LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF
Sbjct: 181 LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF 240

Query: 241 NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN 300
           NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN
Sbjct: 241 NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN 300

Query: 301 QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS 360
           QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS
Sbjct: 301 QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS 360

Query: 361 ESRGETPCSFNDEDEEDDEEDSSSPE 386
           ESRGETPCSFNDEDEEDDEEDSSSPE
Sbjct: 361 ESRGETPCSFNDEDEEDDEEDSSSPE 386


>gi|6005900 transcription factor Dp-1 [Homo sapiens]
          Length = 410

 Score =  437 bits (1124), Expect = e-123
 Identities = 233/386 (60%), Positives = 284/386 (73%), Gaps = 39/386 (10%)

Query: 1   MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKR 60
           ++I TPQR  +S ++++GSP+TP+    +Q   ++++ W  G                KR
Sbjct: 62  VVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAG----------------KR 105

Query: 61  SKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNI 120
           ++KG+KNGKGLRHFSMKVCEKVQRKGTTSYNEVADELV+EF+ ++NH+  +  AYDQKNI
Sbjct: 106 NRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNI 165

Query: 121 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQE 180
           RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLE+E+QRR+ERIKQK++QLQE
Sbjct: 166 RRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQE 225

Query: 181 LLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLF 240
           L+LQQIAFKNLVQRNR  EQQ   PP  NS I LPFII+NTS+KTVIDCSIS+DKFEYLF
Sbjct: 226 LILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLF 285

Query: 241 NFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLN 300
           NFDNTFEIHDDIEVLKRMGM+ GLESG CS EDLK+A+SLVPKALE Y+T+++ G     
Sbjct: 286 NFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTV--- 342

Query: 301 QGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCS 360
            G+ + +  S SN     G     S +  G    A+  LAT           SS  S  S
Sbjct: 343 GGVFITTAGSTSN-----GTRFSASDLTNG----ADGMLAT-----------SSNGSQYS 382

Query: 361 ESRGETPCSFNDEDEEDDEEDSSSPE 386
            SR ETP S+  ED+E+D++ + + E
Sbjct: 383 GSRVETPVSYVGEDDEEDDDFNENDE 408


>gi|189409125 transcription factor Dp family, member 3 [Homo
           sapiens]
          Length = 405

 Score =  330 bits (845), Expect = 2e-90
 Identities = 188/384 (48%), Positives = 248/384 (64%), Gaps = 42/384 (10%)

Query: 1   MIISTPQRLTSSGSVLIGSPYTPAPAMVTQT-HIAEATGWVPGDRKRARKFIDSDFSESK 59
           ++I  PQR  +S   ++GSP  P+    +Q  H   +  W                   +
Sbjct: 57  VVIGMPQRPAASNIPVVGSPNPPSTHFASQNQHSYSSPPWA-----------------GQ 99

Query: 60  RSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKN 119
            ++KG+KNG GL   SMKV E VQRKGTTS  EV  ELV++F  ++NH + +  AYD KN
Sbjct: 100 HNRKGEKNGMGLCRLSMKVWETVQRKGTTSCQEVVGELVAKFRAASNHASPNESAYDVKN 159

Query: 120 IRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQ 179
           I+RR YDALNVLMAMNIIS+EKK+IKWIGL TNSAQ CQNL +E+Q+R+ERIKQK+++LQ
Sbjct: 160 IKRRTYDALNVLMAMNIISREKKKIKWIGLTTNSAQNCQNLRVERQKRLERIKQKQSELQ 219

Query: 180 ELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYL 239
           +L+LQQIAFKNLV RN+  E+Q    P  NS I +PFIII++S+KTVI+CSIS DK EYL
Sbjct: 220 QLILQQIAFKNLVLRNQYVEEQVSQRPLPNSVIHVPFIIISSSKKTVINCSISDDKSEYL 279

Query: 240 FNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWL 299
           F F+++FEIHDD EVL  MGM+FGLESG CS EDLK+A++LVPKALE Y+T+++ G    
Sbjct: 280 FKFNSSFEIHDDTEVLMWMGMTFGLESGSCSAEDLKMARNLVPKALEPYVTEMAQG---- 335

Query: 300 NQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHC 359
             G +  +  S SN     G  L  S +           +A G         +SS  S  
Sbjct: 336 TFGGVFTTAGSRSN-----GTWLSASDLTN---------IAIGML------ATSSGGSQY 375

Query: 360 SESRGETPCSFNDEDEEDDEEDSS 383
           S SR ETP    +E+E+++++D S
Sbjct: 376 SGSRVETPAVEEEEEEDNNDDDLS 399


>gi|12669915 E2F transcription factor 4 [Homo sapiens]
          Length = 413

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 5/75 (6%)

Query: 108 LAADSQAYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGL-PTNSAQECQNLEIEKQ 165
           LAAD+ A  QK   RR+YD  NVL  + +I K+ K  I+W G+ P  + +E  +  IE +
Sbjct: 45  LAADTLAVRQK---RRIYDITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELK 101

Query: 166 RRIERIKQKRAQLQE 180
             IE ++Q+  +L +
Sbjct: 102 AEIEELQQREQELDQ 116


>gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]
          Length = 345

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 13/78 (16%)

Query: 109 AADSQAYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEIEKQRR 167
           AAD+ A  QK   RR+YD  NVL  +++I K+ K  I+W G+       C   E+     
Sbjct: 79  AADTLAVRQK---RRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG----CNTKEV----- 126

Query: 168 IERIKQKRAQLQELLLQQ 185
           I+R++  +A++++L L++
Sbjct: 127 IDRLRYLKAEIEDLELKE 144


>gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]
          Length = 346

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 13/78 (16%)

Query: 109 AADSQAYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEIEKQRR 167
           AAD+ A  QK   RR+YD  NVL  +++I K+ K  I+W G+       C   E+     
Sbjct: 79  AADTLAVRQK---RRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG----CNTKEV----- 126

Query: 168 IERIKQKRAQLQELLLQQ 185
           I+R++  +A++++L L++
Sbjct: 127 IDRLRYLKAEIEDLELKE 144


>gi|4503433 E2F transcription factor 3 [Homo sapiens]
          Length = 465

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 44/216 (20%), Positives = 89/216 (41%), Gaps = 20/216 (9%)

Query: 1   MIISTPQRLTSSGSVLIGSPYTPAP--AMVTQTHIAEATGWVPGDRKRARKFIDSDFSES 58
           ++ S P    ++GS+L  +P+ P+    ++ Q       G   G    A++ ++   S  
Sbjct: 84  LLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGH 143

Query: 59  KRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQ----- 113
           +    G K  KG    +++  +  +   + S     D  +   T     L + S      
Sbjct: 144 QYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLD 203

Query: 114 ----AYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNS----AQECQNLEIEK 164
               A   K  +RR+YD  NVL  +++I K+ K  ++W+G   +       +CQ L    
Sbjct: 204 LNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGL---- 259

Query: 165 QRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQ 200
            + +  + Q+  +L EL+        L+  + +N++
Sbjct: 260 SKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQR 295


>gi|12669911 E2F transcription factor 1 [Homo sapiens]
          Length = 437

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 10/61 (16%)

Query: 121 RRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQ 179
           +RR+YD  NVL  + +I+K+ K  I+W+G  T          +    R+E + Q   QLQ
Sbjct: 164 KRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTT---------VGVGGRLEGLTQDLRQLQ 214

Query: 180 E 180
           E
Sbjct: 215 E 215


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 18/57 (31%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 147 IGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQ 203
           +GLP     + + LE ++Q + + ++++  QL+ L+ Q+   K+LVQ+  Q EQQ +
Sbjct: 363 LGLPEQQVLQLKQLE-KQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQER 418


>gi|145580626 E2F transcription factor 7 [Homo sapiens]
          Length = 911

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 22/169 (13%)

Query: 54  DFSESK--RSKKGDKNGKGLRHFSMK--VCEKVQRKGTTSYNEVADELVSEFTNSNNHLA 109
           DFSE     S    +  K LR  S K  +   V +    + +  A  L+ E  ++ +H  
Sbjct: 268 DFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSK 327

Query: 110 ADSQAYDQKNIRRRVYDALNVLMAMNIISK--------EKKEIKWIGLPTNSAQECQNLE 161
             ++        RR+YD  NVL ++ +I K         K   KWIG    S+ + + ++
Sbjct: 328 FKTKV-------RRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSSDEELVD 380

Query: 162 IEKQRRIERIKQKRAQLQELLLQQIAFK---NLVQRNRQNEQQNQGPPA 207
           +      E  ++   Q+Q    Q++A     N VQ + + +++    P+
Sbjct: 381 VSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERIQRKVNSEPS 429



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)

Query: 121 RRRVYDALNVLMAMNIISK-EKKEIKWIG---LPTNSAQECQNLEIEKQRRIERIKQKRA 176
           RRR+YD +NVL +++++S+  K +  W G   LP  + +  Q L  E     ++ +++ A
Sbjct: 183 RRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLP-KTLRNLQRLGEE-----QKYEEQMA 236

Query: 177 QLQELLLQQIAFKNLVQRNRQNEQQNQGPPALN-STIQLPFIIINTSRKTVIDCSISSDK 235
            LQ+  L  I +K   +R +  +  +Q    L+ S    P    N+ +   +   I S K
Sbjct: 237 YLQQKELDLIDYK-FGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSL--RIMSQK 293

Query: 236 FEYLFNFDNT 245
           F  LF    T
Sbjct: 294 FVMLFLVSKT 303


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 5/119 (4%)

Query: 84   RKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQ-KNIRRRVYDALNVLMAMNIISKEKK 142
            RK T    ++++EL +E + +  + +A  Q   Q K +R ++++    + +    +    
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819

Query: 143  EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQ 201
            E K   L     QE +    EKQ   + +KQK  +L+E+LLQ    + + ++ ++  ++
Sbjct: 1820 EAKIAQLEEQVEQEAR----EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1874


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 5/119 (4%)

Query: 84   RKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQ-KNIRRRVYDALNVLMAMNIISKEKK 142
            RK T    ++++EL +E + +  + +A  Q   Q K +R ++++    + +    +    
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826

Query: 143  EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQ 201
            E K   L     QE +    EKQ   + +KQK  +L+E+LLQ    + + ++ ++  ++
Sbjct: 1827 EAKIAQLEEQVEQEAR----EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 5/119 (4%)

Query: 84   RKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQ-KNIRRRVYDALNVLMAMNIISKEKK 142
            RK T    ++++EL +E + +  + +A  Q   Q K +R ++++    + +    +    
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826

Query: 143  EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQ 201
            E K   L     QE +    EKQ   + +KQK  +L+E+LLQ    + + ++ ++  ++
Sbjct: 1827 EAKIAQLEEQVEQEAR----EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 5/119 (4%)

Query: 84   RKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQ-KNIRRRVYDALNVLMAMNIISKEKK 142
            RK T    ++++EL +E + +  + +A  Q   Q K +R ++++    + +    +    
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819

Query: 143  EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQ 201
            E K   L     QE +    EKQ   + +KQK  +L+E+LLQ    + + ++ ++  ++
Sbjct: 1820 EAKIAQLEEQVEQEAR----EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1874


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 91  NEVADELVSEFTNS----NNHLAADSQAYDQKNIRRRVYDALNVLMAMNI-ISKEKKEIK 145
           N+V DE+  EF       N     + +   Q  I ++  +  N    + I +  EK ++K
Sbjct: 770 NQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLK 829

Query: 146 --------WIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLV-QRNR 196
                   W         E + L+ E+QR ++ I +  AQLQ+L  Q +A K+ V  +N 
Sbjct: 830 EDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNH 889

Query: 197 QNEQ 200
           + E+
Sbjct: 890 EMEE 893


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 26/122 (21%), Positives = 58/122 (47%), Gaps = 5/122 (4%)

Query: 83  QRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKK 142
           Q  G      +   +V +  +  +  AA  +A +   + +      +   A  I++++++
Sbjct: 350 QAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRR 409

Query: 143 EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKR-AQLQELLLQQIAFKNLVQRNRQNEQQ 201
           + +         +E + +E E+Q R+ER + KR A+ + L L++ A K   +R RQ E++
Sbjct: 410 QARL----QKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK 465

Query: 202 NQ 203
            +
Sbjct: 466 KK 467


>gi|38505226 E2F family member 8 [Homo sapiens]
          Length = 867

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 105 NNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISK-EKKEIKWIG 148
           NN +  D  A +    RRR+YD +NVL +++++S+  K    W G
Sbjct: 138 NNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHG 182


>gi|171184451 centrosome-associated protein 350 [Homo sapiens]
          Length = 3117

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 137  ISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFK---NLVQ 193
            + +EK EIK +     +A++ + L +++Q  IE+I+Q   +LQE L      K   +   
Sbjct: 1750 LQQEKAEIKRLQEANKAARKERQLILKQQEEIEKIRQTTIKLQEKLKSAGESKLDSHSDD 1809

Query: 194  RNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVI 227
              + N+  + GP  L +    P  I ++   +++
Sbjct: 1810 DTKDNKATSPGPTDLETRSPSPISISSSETSSIM 1843


>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
           sapiens]
          Length = 551

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 15/124 (12%)

Query: 83  QRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKK 142
           Q+    +  ++AD++V EFT       A+ +A +Q+ IRR     +  L AM    +EK 
Sbjct: 325 QKAELLAQEKLADQMVMEFTKKKMAREAEFEA-EQERIRREKEKEIARLRAM----QEKA 379

Query: 143 EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKR-----AQLQELLLQQIAFKN-----LV 192
           +          A+  Q +   + RR E+   ++     A+L++  L+Q+AFK       V
Sbjct: 380 QDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQV 439

Query: 193 QRNR 196
           QR+R
Sbjct: 440 QRDR 443


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 26/128 (20%), Positives = 62/128 (48%), Gaps = 17/128 (13%)

Query: 80  EKVQRKGTTSYNEVAD---ELVSEFTNSN-------NHLAADSQAYDQKNIRRRVYDALN 129
           EKV+++    Y+E+     +L  E + S+       NH+   S A D+       ++A+N
Sbjct: 112 EKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR-------FNAMN 164

Query: 130 VLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFK 189
             +A + I  +K  +      +N   + +NL+   +  ++++++K+ QL+   ++    K
Sbjct: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224

Query: 190 NLVQRNRQ 197
             V+ +++
Sbjct: 225 MKVESSQE 232


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 26/128 (20%), Positives = 62/128 (48%), Gaps = 17/128 (13%)

Query: 80  EKVQRKGTTSYNEVAD---ELVSEFTNSN-------NHLAADSQAYDQKNIRRRVYDALN 129
           EKV+++    Y+E+     +L  E + S+       NH+   S A D+       ++A+N
Sbjct: 112 EKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR-------FNAMN 164

Query: 130 VLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFK 189
             +A + I  +K  +      +N   + +NL+   +  ++++++K+ QL+   ++    K
Sbjct: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224

Query: 190 NLVQRNRQ 197
             V+ +++
Sbjct: 225 MKVESSQE 232


>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
          Length = 438

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 26/128 (20%), Positives = 62/128 (48%), Gaps = 17/128 (13%)

Query: 80  EKVQRKGTTSYNEVAD---ELVSEFTNSN-------NHLAADSQAYDQKNIRRRVYDALN 129
           EKV+++    Y+E+     +L  E + S+       NH+   S A D+       ++A+N
Sbjct: 112 EKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR-------FNAMN 164

Query: 130 VLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFK 189
             +A + I  +K  +      +N   + +NL+   +  ++++++K+ QL+   ++    K
Sbjct: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224

Query: 190 NLVQRNRQ 197
             V+ +++
Sbjct: 225 MKVESSQE 232


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 26/128 (20%), Positives = 62/128 (48%), Gaps = 17/128 (13%)

Query: 80  EKVQRKGTTSYNEVAD---ELVSEFTNSN-------NHLAADSQAYDQKNIRRRVYDALN 129
           EKV+++    Y+E+     +L  E + S+       NH+   S A D+       ++A+N
Sbjct: 112 EKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR-------FNAMN 164

Query: 130 VLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFK 189
             +A + I  +K  +      +N   + +NL+   +  ++++++K+ QL+   ++    K
Sbjct: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224

Query: 190 NLVQRNRQ 197
             V+ +++
Sbjct: 225 MKVESSQE 232


>gi|4758226 E2F transcription factor 2 [Homo sapiens]
          Length = 437

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 11/74 (14%)

Query: 121 RRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQ 179
           +RR+YD  NVL  + +I K+ K  I+W+G              E   R  + +Q   +L+
Sbjct: 166 KRRIYDITNVLEGIQLIRKKAKNNIQWVGRGM----------FEDPTRPGKQQQLGQELK 215

Query: 180 ELLLQQIAFKNLVQ 193
           EL+  + A   L+Q
Sbjct: 216 ELMNTEQALDQLIQ 229


>gi|109637795 E2F transcription factor 6 [Homo sapiens]
          Length = 281

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 11/72 (15%)

Query: 121 RRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNS----------AQECQNLEIEKQRRIE 169
           +RRVYD  NVL  ++++ K+ K  I+WIG   ++           +E  +L   +    E
Sbjct: 100 KRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDE 159

Query: 170 RIKQKRAQLQEL 181
            IK    QL EL
Sbjct: 160 LIKDCAQQLFEL 171


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 20/119 (16%), Positives = 55/119 (46%)

Query: 84  RKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKE 143
           RK      E  +  + EF N       D  A  Q+N  +R+     +   +  + +++++
Sbjct: 256 RKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQRED 315

Query: 144 IKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQN 202
           ++ +       ++ +  + + +   E+  +K+ ++++   +Q+A K LV +  + E++N
Sbjct: 316 LEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEEN 374


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 46/224 (20%), Positives = 99/224 (44%), Gaps = 32/224 (14%)

Query: 169 ERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQN----QGPPALNSTIQLPFIIINTSRK 224
           ++IK+K+ Q ++    +I  KNLV++ ++ ++ N    +    L+++I +  +   TS K
Sbjct: 92  KKIKKKKTQTKK----EIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKM--KTSCK 145

Query: 225 TVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKA 284
             ID +IS  K    F   N  E  + ++            +   SLE+ +       + 
Sbjct: 146 FKIDSNISPKKDSKEFTQKNKKEKKNIVQ-----------HTTDSSLEEKQ-------RT 187

Query: 285 LEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQF 344
           L+   ++I   P  +         QSV  L +T  +   ++S +  +C D +      + 
Sbjct: 188 LDSGTSEIVKSPR-IECSKTRREMQSVVQLIMTRDSDGYENSTDGEMC-DKDALEEDSES 245

Query: 345 LAP--NSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 386
           ++   +  +S +  +    + G+   S +DE+E++DEE+    +
Sbjct: 246 VSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDED 289



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 22/96 (22%), Positives = 48/96 (50%), Gaps = 4/96 (4%)

Query: 54  DFSESKRSKKGDKNGKGLRHFS-MKVCEKVQRKGTTSYNEVADELVS--EFTNSNNHLAA 110
           +  E  R  K DK  + + H    K+   V ++G    +   ++L    + ++S+++L+ 
Sbjct: 24  EMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSNLSG 83

Query: 111 -DSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIK 145
            DS+A  QK I+++       + + N++ K+K+  K
Sbjct: 84  EDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKK 119


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 4/67 (5%)

Query: 320 ATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDE 379
           A +P   +  G  L    A+  G  LA +S +SSS  S  SES  E     ++EDEE++E
Sbjct: 451 AKMPDEPLEPGP-LPVSTAMPPG--LAKSSSESSSEESS-SESSSEEEEEEDEEDEEEEE 506

Query: 380 EDSSSPE 386
            +SS  E
Sbjct: 507 SESSDSE 513


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 4/67 (5%)

Query: 320 ATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDE 379
           A +P   +  G  L    A+  G  LA +S +SSS  S  SES  E     ++EDEE++E
Sbjct: 451 AKMPDEPLEPGP-LPVSTAMPPG--LAKSSSESSSEESS-SESSSEEEEEEDEEDEEEEE 506

Query: 380 EDSSSPE 386
            +SS  E
Sbjct: 507 SESSDSE 513


>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
           sapiens]
          Length = 602

 Score = 32.0 bits (71), Expect = 0.97
 Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 10/121 (8%)

Query: 268 KCSLEDLKLAKSLVPKALEGYITDISTGPSW--LNQGLLLNSTQSVSNLDLTTGATLPQS 325
           K + ED+K+   L+ +    ++  +   P W  +  G++L   +     DL T A + QS
Sbjct: 168 KITQEDVKVMLYLLEEVCTAFLIQLLP-PVWESVTYGMVLQRER-----DLNTAARIGQS 221

Query: 326 SVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSP 385
            V Q   L  E +    + L  ++ +      H    R E    ++D DEED++E+    
Sbjct: 222 LVKQNSVLMEENSKL--EALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEE 279

Query: 386 E 386
           E
Sbjct: 280 E 280


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,174,476
Number of Sequences: 37866
Number of extensions: 611131
Number of successful extensions: 4016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 3886
Number of HSP's gapped (non-prelim): 162
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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