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Search of human proteins with 5453990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453990 proteasome activator subunit 1 isoform 1 [Homo
sapiens]
(249 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453990 proteasome activator subunit 1 isoform 1 [Homo sapiens] 499 e-142
gi|30581141 proteasome activator subunit 1 isoform 2 [Homo sapiens] 448 e-126
gi|30410792 proteasome activator subunit 2 [Homo sapiens] 224 5e-59
gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens] 204 4e-53
gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens] 195 3e-50
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 43 2e-04
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 39 0.004
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 39 0.004
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 39 0.004
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 39 0.006
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 38 0.007
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 38 0.009
gi|113204622 stromal membrane-associated GTPase-activating prote... 38 0.009
gi|6005757 chromatin-specific transcription elongation factor la... 37 0.012
gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo s... 37 0.016
gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa... 37 0.016
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 37 0.016
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 36 0.027
gi|110349794 homer 2 isoform 3 [Homo sapiens] 36 0.027
gi|25777600 proteasome 26S non-ATPase subunit 1 [Homo sapiens] 36 0.027
gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens] 36 0.036
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 36 0.036
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 36 0.036
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 35 0.047
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 35 0.061
gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 35 0.061
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 35 0.061
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 35 0.061
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 35 0.061
gi|148747864 JAW1-related protein isoform a [Homo sapiens] 35 0.061
>gi|5453990 proteasome activator subunit 1 isoform 1 [Homo sapiens]
Length = 249
Score = 499 bits (1286), Expect = e-142
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP 60
MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
Sbjct: 1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP 60
Query: 61 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE 120
LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
Sbjct: 61 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE 120
Query: 121 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE 180
IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
Sbjct: 121 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE 180
Query: 181 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP 240
RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP
Sbjct: 181 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP 240
Query: 241 RGETKGMIY 249
RGETKGMIY
Sbjct: 241 RGETKGMIY 249
>gi|30581141 proteasome activator subunit 1 isoform 2 [Homo sapiens]
Length = 250
Score = 448 bits (1153), Expect = e-126
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP 60
MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
Sbjct: 1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP 60
Query: 61 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE 120
LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
Sbjct: 61 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE 120
Query: 121 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE 180
IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
Sbjct: 121 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE 180
Query: 181 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAY 223
RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAY
Sbjct: 181 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAY 223
>gi|30410792 proteasome activator subunit 2 [Homo sapiens]
Length = 239
Score = 224 bits (571), Expect = 5e-59
Identities = 118/246 (47%), Positives = 166/246 (67%), Gaps = 13/246 (5%)
Query: 4 LRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDI 63
+R+ EA+ +V+VFR++L + E L + P+KI L+ L+E +LN A+L++L+APLDI
Sbjct: 7 VRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDI 66
Query: 64 PVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKD 123
P+PDP + ++ E KQ++KE CG + NEK++ LL +KPE+
Sbjct: 67 PIPDPPPKDDEMETDKQEKKEVHK-------------CGFLPGNEKVLSLLALVKPEVWT 113
Query: 124 VIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGD 183
+ E+ LV TW+Q IP+IEDGN+FGVA+QEKV E + ++ TK+E F T ISKYFSERGD
Sbjct: 114 LKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGD 173
Query: 184 AVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGE 243
AV KA+K+ HV DYR LVHE DEA Y ++R MV+++R YA LY II N EK+ P+GE
Sbjct: 174 AVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGE 233
Query: 244 TKGMIY 249
K +Y
Sbjct: 234 EKPSMY 239
>gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens]
Length = 254
Score = 204 bits (520), Expect = 4e-53
Identities = 102/253 (40%), Positives = 166/253 (65%), Gaps = 6/253 (2%)
Query: 2 AMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPL 61
++L+V E + KVD FRE + ++ E+L+ ++FPKK+ ELD+FLKEP LN +L+ + + +
Sbjct: 3 SLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDM 62
Query: 62 DIPVPDPVKEKEKEE-----RKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQR 116
++PVPDP+ + K++ ++ +E +G P G + N+++V ++++
Sbjct: 63 NLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPN-GMLKSNQQLVDIIEK 121
Query: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISK 176
+KPEI+ +IE+ N V W+QL IPRIEDGNNFGV++QE+ + ++ ++ + QIS+
Sbjct: 122 VKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISR 181
Query: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236
Y+ R V+K AK PHV DYR+ V E+DE EY +RL++ E+RN Y L+D+ILKN EK
Sbjct: 182 YYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEK 241
Query: 237 LKKPRGETKGMIY 249
+K+PR +Y
Sbjct: 242 IKRPRSSNAETLY 254
>gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens]
Length = 267
Score = 195 bits (496), Expect = 3e-50
Identities = 102/266 (38%), Positives = 166/266 (62%), Gaps = 19/266 (7%)
Query: 2 AMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPL 61
++L+V E + KVD FRE + ++ E+L+ ++FPKK+ ELD+FLKEP LN +L+ + + +
Sbjct: 3 SLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDM 62
Query: 62 DIPVPDPVKEKEKEE-----RKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQR 116
++PVPDP+ + K++ ++ +E +G P G + N+++V ++++
Sbjct: 63 NLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPN-GMLKSNQQLVDIIEK 121
Query: 117 LKPEIKDVIEQLNL-------------VTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSL 163
+KPEI+ +IE+ N V W+QL IPRIEDGNNFGV++QE+ + ++
Sbjct: 122 VKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTV 181
Query: 164 HTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAY 223
++ + QIS+Y+ R V+K AK PHV DYR+ V E+DE EY +RL++ E+RN Y
Sbjct: 182 ESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQY 241
Query: 224 AVLYDIILKNFEKLKKPRGETKGMIY 249
L+D+ILKN EK+K+PR +Y
Sbjct: 242 VTLHDMILKNIEKIKRPRSSNAETLY 267
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 15 DVFREDLCTKTENLLGSYFPKKISELDAFLKEP-ALNEANLSNLKAPLDIPVPDPVKEKE 73
++ +E LC K + +L + KK ++++ L+E A +A S + PL P P P E E
Sbjct: 864 EIDKESLCEKVKEILTTEIAKKKNKVEKKLEEKEAEKKAAASLAELPLPTPPPAPPPEPE 923
Query: 74 KEERKKQQEKEDKDEKKKGEDEDKGP 99
KE+ Q K KG+ + + P
Sbjct: 924 KEKEIHQSHVASKTPTAKGKPQSEAP 949
Score = 29.6 bits (65), Expect = 2.6
Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 15/126 (11%)
Query: 60 PLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCG---PVNCNEKIVVLLQR 116
P D P K+ +K+ +K+ +D+K KG K PP PV + + ++R
Sbjct: 1285 PADPKEKSPQMGANKKVKKEPPKKKQEDKKPKG----KSPPMAEATPVIVTTEEIAEIKR 1340
Query: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGV-AVQEKVFELMTSLHTKLEGFHTQIS 175
K E++ I++ +L LQ + E F + ++ K L+ L TK+ + +
Sbjct: 1341 -KNELRVKIKEEHLAA--LQFE----EIATQFRLELIKTKALALLEDLVTKVVDVYKLME 1393
Query: 176 KYFSER 181
K+ ER
Sbjct: 1394 KWLGER 1399
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 38.9 bits (89), Expect = 0.004
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 10/91 (10%)
Query: 65 VPDPVKEKEKEERKKQQEKEDKDEKK---KGEDEDKGPPCGPVN-----CNEKIVVLLQR 116
V D +E+E+EE + ++E+ED D+ + +GE+E P V C+EK LL+
Sbjct: 62 VNDLGEEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEE 121
Query: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNN 147
K ++ +E + VT +QIPR ++ N
Sbjct: 122 PKTTSEETLEDCSEVTP--AMQIPRTKEEAN 150
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 38.9 bits (89), Expect = 0.004
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 10/91 (10%)
Query: 65 VPDPVKEKEKEERKKQQEKEDKDEKK---KGEDEDKGPPCGPVN-----CNEKIVVLLQR 116
V D +E+E+EE + ++E+ED D+ + +GE+E P V C+EK LL+
Sbjct: 263 VNDLGEEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEE 322
Query: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNN 147
K ++ +E + VT +QIPR ++ N
Sbjct: 323 PKTTSEETLEDCSEVTP--AMQIPRTKEEAN 351
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 38.9 bits (89), Expect = 0.004
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 10/91 (10%)
Query: 65 VPDPVKEKEKEERKKQQEKEDKDEKK---KGEDEDKGPPCGPVN-----CNEKIVVLLQR 116
V D +E+E+EE + ++E+ED D+ + +GE+E P V C+EK LL+
Sbjct: 263 VNDLGEEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEE 322
Query: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNN 147
K ++ +E + VT +QIPR ++ N
Sbjct: 323 PKTTSEETLEDCSEVTP--AMQIPRTKEEAN 351
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 45 KEPALNEANLSNLKAP-LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGP 99
K P N K+P D+P+ + +K K++ KK +EKE EKKK +++ K P
Sbjct: 815 KLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSP 870
Score = 32.7 bits (73), Expect = 0.30
Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 57 LKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKG 98
LK P +P+ D + E+E R +Q+ ++DK KK+ E E KG
Sbjct: 713 LKVP-GLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKG 753
Score = 31.6 bits (70), Expect = 0.67
Identities = 15/41 (36%), Positives = 27/41 (65%), Gaps = 5/41 (12%)
Query: 67 DPVKEKEKEERK-----KQQEKEDKDEKKKGEDEDKGPPCG 102
D K+KEKE++K K++ +++K+E+ KG+ + K P G
Sbjct: 857 DKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPG 897
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 38.1 bits (87), Expect = 0.007
Identities = 20/57 (35%), Positives = 34/57 (59%), Gaps = 6/57 (10%)
Query: 47 PALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKK------GEDEDK 97
P+LNE N+ + + KE+E+EE K ++EKE+K+ +++ GE+EDK
Sbjct: 889 PSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESLSVGEEEDK 945
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 37.7 bits (86), Expect = 0.009
Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query: 36 KISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDE 95
+++EL LK A++E + +AP++ P K KEKE++KK +EKE + K K E+E
Sbjct: 462 RLAELQEQLK--AVHEQLAALSQAPVNKPKKKKEK-KEKEKKKKDKEKEKEKHKVKAEEE 518
Query: 96 DKGPPCGP 103
K P
Sbjct: 519 KKAKVAPP 526
Score = 28.5 bits (62), Expect = 5.7
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 35 KKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGED 94
K + E A L + +N+ K + D KEKEK + K ++EK+ K +
Sbjct: 471 KAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQA 530
Query: 95 EDKGPPCGPVN 105
+ K P N
Sbjct: 531 QQKKAPAKKAN 541
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 37.7 bits (86), Expect = 0.009
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Query: 32 YFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKK 91
+F + E + + A+ N+S+ APL V P + ++ K ++EKE K E+KK
Sbjct: 117 FFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKK 176
Query: 92 GEDEDKGPPCGPVNCNEKIVVLLQRLKPE 120
E E + P P+ EK+ Q+L+P+
Sbjct: 177 REKEPE-KPAKPLTA-EKLQKKDQQLEPK 203
>gi|6005757 chromatin-specific transcription elongation factor large
subunit [Homo sapiens]
Length = 1047
Score = 37.4 bits (85), Expect = 0.012
Identities = 42/183 (22%), Positives = 77/183 (42%), Gaps = 39/183 (21%)
Query: 55 SNLKAPLDIPVPDPVKEKE----KEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKI 110
SN+KAP + VP + KE +K+ + +E ++++K+G + + +
Sbjct: 603 SNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEG-----------IVKQDSL 651
Query: 111 VVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKV-------------- 156
V+ L R P++KD+ + N+ +Q + +G F +KV
Sbjct: 652 VINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQP 711
Query: 157 --FELMTSLHTKLEGF-------HTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEA 207
E++ LH L+ HT + ++++E G+ T K H+ D L E E
Sbjct: 712 CDGEMIIVLHFHLKNAIMFGKKRHTDV-QFYTEVGEITTDLGKHQHMHDRDDLYAEQMER 770
Query: 208 EYR 210
E R
Sbjct: 771 EMR 773
>gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo
sapiens]
Length = 612
Score = 37.0 bits (84), Expect = 0.016
Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 37 ISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDED 96
I EL K+ N + ++P +P KE+ ER+++ E+E+ +++ + EDED
Sbjct: 369 IEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDED 428
Query: 97 KGPPCGPVNCNEKIVVL---LQRLKPEIKDVIEQ 127
+ G + ++L RL+ E+K +E+
Sbjct: 429 ERQLLGEFEKELEGILLPSDRDRLRSEVKAGMER 462
>gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo
sapiens]
Length = 667
Score = 37.0 bits (84), Expect = 0.016
Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 37 ISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDED 96
I EL K+ N + ++P +P KE+ ER+++ E+E+ +++ + EDED
Sbjct: 369 IEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDED 428
Query: 97 KGPPCGPVNCNEKIVVL---LQRLKPEIKDVIEQ 127
+ G + ++L RL+ E+K +E+
Sbjct: 429 ERQLLGEFEKELEGILLPSDRDRLRSEVKAGMER 462
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 37.0 bits (84), Expect = 0.016
Identities = 17/44 (38%), Positives = 30/44 (68%)
Query: 67 DPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKI 110
+ V+E+EKEE K++ E+E++ E++K EDE++ G EK+
Sbjct: 128 EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
Score = 36.6 bits (83), Expect = 0.021
Identities = 18/52 (34%), Positives = 32/52 (61%)
Query: 65 VPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQR 116
V + KE+EKEE ++++EKE++ E+ + E+E +G E+I +QR
Sbjct: 130 VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
Score = 33.5 bits (75), Expect = 0.18
Identities = 12/30 (40%), Positives = 26/30 (86%)
Query: 68 PVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
PV+E+E EE +++ E+E+K+E+K+ ++E++
Sbjct: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEE 146
Score = 30.0 bits (66), Expect = 2.0
Identities = 11/26 (42%), Positives = 22/26 (84%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDE 95
+E+E EE +K++EKE+ +E+++ E+E
Sbjct: 126 EEEEVEEEEKEEEKEEDEEEEEKEEE 151
Score = 29.6 bits (65), Expect = 2.6
Identities = 10/35 (28%), Positives = 28/35 (80%)
Query: 63 IPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
+PV + E+E+EE ++++++E+K+E ++ E++++
Sbjct: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE 150
Score = 29.3 bits (64), Expect = 3.3
Identities = 10/38 (26%), Positives = 29/38 (76%)
Query: 60 PLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
P++ + +E+ +EE K+++++ED++E++K E++++
Sbjct: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE 154
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 36.2 bits (82), Expect = 0.027
Identities = 47/218 (21%), Positives = 91/218 (41%), Gaps = 21/218 (9%)
Query: 36 KISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDE 95
+I+E + L E NL+ ++ ++ + D + +KEE K +QE E K GE
Sbjct: 1007 RIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEE-KTRQELEKAKRKLDGETT 1065
Query: 96 DKGPPCGPVNCN-EKIVVLLQRLKPEIKDVI-----EQLN-----LVTTWLQLQIPRIED 144
D + +++ + L + + E++ + E L+ V LQ QI +++
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 145 GNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHEL 204
A + K + L +LE T++ T AA+Q Q V EL
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLD------TTAAQQELRTKREQEVAEL 1179
Query: 205 DEA---EYRDIRLMVMEIRNAYAVLYDIILKNFEKLKK 239
+A E ++ + ++R +A + + + E+ K+
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
>gi|110349794 homer 2 isoform 3 [Homo sapiens]
Length = 288
Score = 36.2 bits (82), Expect = 0.027
Identities = 45/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%)
Query: 69 VKEKEKEERKKQQEKEDKDEKKK------GEDEDKGPPCGPVNC-----NEKIVVLLQRL 117
VKE K + K QEK + G D++K GP N N+K+ + L +
Sbjct: 106 VKEAAKIAKDKTQEKIETSSNHSQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQS 165
Query: 118 KPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQIS-- 175
+K+ I + T L+ +I +E ++EK EL L + E +S
Sbjct: 166 AANVKNEINREKEKNTQLKRRIEELE------AELREKETEL-KDLRKQSEIIPQLMSEC 218
Query: 176 KYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVL 226
+Y SE+ +A + Q R L +++E++YR L V E+++ VL
Sbjct: 219 EYVSEKLEAAER-DNQNLEDKVRSLKTDIEESKYRQRHLKV-ELKSFLEVL 267
>gi|25777600 proteasome 26S non-ATPase subunit 1 [Homo sapiens]
Length = 953
Score = 36.2 bits (82), Expect = 0.027
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 23/88 (26%)
Query: 31 SYFPKKISELDAFLKEPALNEANLSNLK-------APLDIP--------------VPDPV 69
+Y P + L+ LK P + SN K APL++P +
Sbjct: 782 AYTPTCVIGLNKDLKMPKVQYK--SNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKA 839
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+KEKE+ KK++EK + DE +K E+++K
Sbjct: 840 KKKEKEKEKKEEEKMEVDEAEKKEEKEK 867
>gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens]
Length = 4967
Score = 35.8 bits (81), Expect = 0.036
Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 10/53 (18%)
Query: 52 ANLSNLKAPLDIPVPDP-VKEKEKEERKKQQEKEDKD------EKKKGEDEDK 97
A LS+L + PVP P V+EK +E++ K++EKE+K+ EK +GED +K
Sbjct: 4400 AGLSDL---MSNPVPMPEVQEKFQEQKAKEEEKEEKEETKSEPEKAEGEDGEK 4449
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 35.8 bits (81), Expect = 0.036
Identities = 14/45 (31%), Positives = 29/45 (64%)
Query: 56 NLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPP 100
+L P + P P E+EE ++++E+E+ +E+++ ED ++ PP
Sbjct: 296 DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPP 340
Score = 33.5 bits (75), Expect = 0.18
Identities = 18/71 (25%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 42 AFLKEPALNEANLSNLKAPLDIPVPDPVKEK---------EKEERKKQQEKEDKDEKKKG 92
A +++ +EA ++L AP + +P +E+ E+EE ++++E+E ++E+++
Sbjct: 274 AAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
Query: 93 EDEDKGPPCGP 103
+ E+ PP P
Sbjct: 334 DSEEAPPPLSP 344
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 35.8 bits (81), Expect = 0.036
Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 36 KISELDAFLKEPALNEANLSN--LKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGE 93
++ E +KEP++ EA ++ LK P P+P+P + ++ KK++EKE + +
Sbjct: 222 ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281
Query: 94 DEDK 97
+ +
Sbjct: 282 SKSR 285
Score = 28.5 bits (62), Expect = 5.7
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 65 VPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
+P E +KEE K++Q +++K K +DEDK
Sbjct: 119 IPSAFLELKKEEIKQRQIEQEKLASMKKQDEDK 151
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 35.4 bits (80), Expect = 0.047
Identities = 14/28 (50%), Positives = 24/28 (85%)
Query: 69 VKEKEKEERKKQQEKEDKDEKKKGEDED 96
+KEKE+EE KK++E + K+EK++ E+E+
Sbjct: 373 MKEKEEEEMKKEEEMKKKEEKEEEEEEE 400
Score = 29.3 bits (64), Expect = 3.3
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 67 DPVKEKEKEER---KKQQEKEDKDEKKKGEDEDKGPPCGP 103
+ +K+KE+EE K ++E E KDE+ + ED + P P
Sbjct: 399 EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEP 438
Score = 28.1 bits (61), Expect = 7.5
Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 42 AFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
AF +E + E +K ++ + +E+E+EE K+++E+E+ K + E E K
Sbjct: 368 AFQQE--MKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESK 421
>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
Length = 652
Score = 35.0 bits (79), Expect = 0.061
Identities = 17/61 (27%), Positives = 33/61 (54%)
Query: 37 ISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDED 96
I EL K+ N + ++P +P KE+ ER+++ E+E+ +++ + EDED
Sbjct: 369 IEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDED 428
Query: 97 K 97
+
Sbjct: 429 E 429
Score = 28.5 bits (62), Expect = 5.7
Identities = 10/25 (40%), Positives = 18/25 (72%)
Query: 67 DPVKEKEKEERKKQQEKEDKDEKKK 91
DP +++E EE + + E ED+DE ++
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDER 430
>gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo
sapiens]
Length = 597
Score = 35.0 bits (79), Expect = 0.061
Identities = 17/61 (27%), Positives = 33/61 (54%)
Query: 37 ISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDED 96
I EL K+ N + ++P +P KE+ ER+++ E+E+ +++ + EDED
Sbjct: 369 IEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDED 428
Query: 97 K 97
+
Sbjct: 429 E 429
Score = 28.5 bits (62), Expect = 5.7
Identities = 10/25 (40%), Positives = 18/25 (72%)
Query: 67 DPVKEKEKEERKKQQEKEDKDEKKK 91
DP +++E EE + + E ED+DE ++
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDER 430
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 35.0 bits (79), Expect = 0.061
Identities = 18/43 (41%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 56 NLKAPLD-IPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDK 97
+L PL +P + KEKEKE++KK+++K+ K +KKK + + K
Sbjct: 91 SLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK 133
Score = 31.6 bits (70), Expect = 0.67
Identities = 13/28 (46%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
KEKEK+++KK+++K+ K +KKK + + K
Sbjct: 108 KEKEKKKKKKKKKKKKKKKKKKKKKKKK 135
Score = 30.0 bits (66), Expect = 2.0
Identities = 12/28 (42%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
KEK+K+++KK+++K+ K +KKK + + K
Sbjct: 110 KEKKKKKKKKKKKKKKKKKKKKKKKKKK 137
Score = 28.5 bits (62), Expect = 5.7
Identities = 11/28 (39%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+K+K+++KK+++K+ K +KKK + + K
Sbjct: 112 KKKKKKKKKKKKKKKKKKKKKKKKKKKK 139
Score = 28.5 bits (62), Expect = 5.7
Identities = 11/28 (39%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+K+K+++KK+++K+ K +KKK + + K
Sbjct: 113 KKKKKKKKKKKKKKKKKKKKKKKKKKKK 140
Score = 28.1 bits (61), Expect = 7.5
Identities = 11/28 (39%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+K+K+++KK+++K+ K +KKK + + K
Sbjct: 115 KKKKKKKKKKKKKKKKKKKKKKKKKKRK 142
Score = 27.7 bits (60), Expect = 9.7
Identities = 11/28 (39%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+K+K+++KK+++K+ K +KKK + + K
Sbjct: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRK 144
Score = 27.7 bits (60), Expect = 9.7
Identities = 11/28 (39%), Positives = 23/28 (82%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDK 97
K+K+K+++KK+++K+ K +KKK + + K
Sbjct: 119 KKKKKKKKKKKKKKKKKKKKKKRKRKRK 146
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 35.0 bits (79), Expect = 0.061
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 19 EDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERK 78
E L TE L S +K + +EP E ++ K+P+ P+ +E+ ++E +
Sbjct: 471 EALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE 530
Query: 79 KQQ-EKEDKDEKKKGEDEDKG 98
+ Q E+E++DE K + ++G
Sbjct: 531 EGQEEEEEEDEGAKSDQAEEG 551
Score = 27.7 bits (60), Expect = 9.7
Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 69 VKEKEKEERKKQQEKEDKD--EKKKGEDEDK 97
VKE KEE+ +++E++ KD EKKK E K
Sbjct: 709 VKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 739
Score = 27.7 bits (60), Expect = 9.7
Identities = 33/118 (27%), Positives = 45/118 (38%), Gaps = 18/118 (15%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLN 129
KEKEK + E+E D+ KG ++ G V E++ Q K + E+
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE---QETKEKGSGREEEKG 828
Query: 130 LVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTK 187
+VT L L D G +EKV T + K SE GD TK
Sbjct: 829 VVTNGLDLS---PADEKKGGDKSEEKVVVTKT------------VEKITSEGGDGATK 871
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 35.0 bits (79), Expect = 0.061
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 19 EDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERK 78
E L TE L S +K + +EP E ++ K+P+ P+ +E+ ++E +
Sbjct: 95 EALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE 154
Query: 79 KQQ-EKEDKDEKKKGEDEDKG 98
+ Q E+E++DE K + ++G
Sbjct: 155 EGQEEEEEEDEGAKSDQAEEG 175
Score = 27.7 bits (60), Expect = 9.7
Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 69 VKEKEKEERKKQQEKEDKD--EKKKGEDEDK 97
VKE KEE+ +++E++ KD EKKK E K
Sbjct: 333 VKEAPKEEKVEKKEEKPKDVPEKKKAESPVK 363
Score = 27.7 bits (60), Expect = 9.7
Identities = 33/118 (27%), Positives = 45/118 (38%), Gaps = 18/118 (15%)
Query: 70 KEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLN 129
KEKEK + E+E D+ KG ++ G V E++ Q K + E+
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE---QETKEKGSGREEEKG 452
Query: 130 LVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTK 187
+VT L L D G +EKV T + K SE GD TK
Sbjct: 453 VVTNGLDLS---PADEKKGGDKSEEKVVVTKT------------VEKITSEGGDGATK 495
>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
Length = 903
Score = 35.0 bits (79), Expect = 0.061
Identities = 17/50 (34%), Positives = 32/50 (64%), Gaps = 3/50 (6%)
Query: 72 KEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEI 121
KE+EE +K + E+ +E ++ E+E+KGP + E++V LQ + P++
Sbjct: 793 KEEEEEQKSESPEEPEEVEETEEEEKGPRSSKL---EELVHFLQVMYPKL 839
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,972,744
Number of Sequences: 37866
Number of extensions: 502570
Number of successful extensions: 11961
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 359
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 6482
Number of HSP's gapped (non-prelim): 4059
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.