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Search of human proteins with 54112390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
subunit 1 [Homo sapiens]
(1091 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su... 2219 0.0
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 1172 0.0
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 1166 0.0
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ... 401 e-111
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun... 394 e-109
gi|110578649 cache domain containing 1 [Homo sapiens] 98 5e-20
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 61 7e-09
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ... 47 8e-05
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 47 1e-04
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 47 1e-04
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 43 0.002
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 41 0.005
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 40 0.016
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 40 0.016
gi|148886654 polydom [Homo sapiens] 38 0.046
gi|11321565 matrilin 3 precursor [Homo sapiens] 36 0.23
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 35 0.51
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 34 0.66
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 34 0.66
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 34 0.66
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 32 2.5
gi|239787094 A20-binding inhibitor of NF-kappaB activation 2 iso... 32 3.3
gi|239787092 A20-binding inhibitor of NF-kappaB activation 2 iso... 32 3.3
gi|33469964 splicing factor 4 [Homo sapiens] 32 3.3
gi|122937404 membrane bound O-acyltransferase domain containing ... 32 3.3
gi|20127561 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1... 32 4.3
gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, ... 32 4.3
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 31 7.3
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 31 7.3
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [... 31 7.3
>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta subunit
1 [Homo sapiens]
Length = 1091
Score = 2219 bits (5750), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI 60
MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
Sbjct: 1 MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI 60
Query: 61 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN 120
YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
Sbjct: 61 YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN 120
Query: 121 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL 180
EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
Sbjct: 121 EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL 180
Query: 181 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR 240
NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
Sbjct: 181 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR 240
Query: 241 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD 300
RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
Sbjct: 241 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD 300
Query: 301 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML 360
VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
Sbjct: 301 VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML 360
Query: 361 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR 420
FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
Sbjct: 361 FTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR 420
Query: 421 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK 480
INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK
Sbjct: 421 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK 480
Query: 481 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL 540
NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL
Sbjct: 481 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL 540
Query: 541 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL 600
DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL
Sbjct: 541 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL 600
Query: 601 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI 660
ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI
Sbjct: 601 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI 660
Query: 661 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR 720
SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR
Sbjct: 661 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKAR 720
Query: 721 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI 780
FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI
Sbjct: 721 FVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGI 780
Query: 781 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI 840
MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI
Sbjct: 781 MVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVI 840
Query: 841 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ 900
LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ
Sbjct: 841 LDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQ 900
Query: 901 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ 960
GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ
Sbjct: 901 GAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQ 960
Query: 961 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI 1020
SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI
Sbjct: 961 SCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLI 1020
Query: 1021 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL 1080
QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL
Sbjct: 1021 QAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLL 1080
Query: 1081 WLVSGSTHRLL 1091
WLVSGSTHRLL
Sbjct: 1081 WLVSGSTHRLL 1091
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta subunit
2 isoform b [Homo sapiens]
Length = 1143
Score = 1172 bits (3032), Expect = 0.0
Identities = 595/1095 (54%), Positives = 768/1095 (70%), Gaps = 35/1095 (3%)
Query: 7 LALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQD 66
L L L L L +S FP T++ W ++++++ + + GV QL +IY+ ++
Sbjct: 44 LWLLLPLLPLLAAPGASAYSFPQQHTMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRN 103
Query: 67 LYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYN 126
L+ V+ N ++LVE A DIE LL + +AL RLA AE Q AH+W+++ ++VYY+
Sbjct: 104 LFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYD 163
Query: 127 AKDDL---DPEKNDSEPGSQR--IKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLN 181
AK D DPE D E GS+ ++ FIED NF +++Y +AAV IPTDIY+GST++LN
Sbjct: 164 AKADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILN 223
Query: 182 ELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRR 241
ELNWT AL+ VF +NR +DP+LLWQVFGSATG+ RYYPA+PW R P KIDLYDVRRR
Sbjct: 224 ELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATPW----RAPKKIDLYDVRRR 279
Query: 242 PWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDV 301
PWYIQGA+SPKDM+I+VDVSGSVSGLTLKL++TSV EML+TLSDDD+VNVASFN AQ V
Sbjct: 280 PWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPV 339
Query: 302 SCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLF 361
SCF HLVQANVRNKKV K+AV + AKG T YK GF +AF+QL N N++RANCNK+IM+F
Sbjct: 340 SCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMF 399
Query: 362 TDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR 420
TDGGE+R Q++F KYN ++ VRVFTFSVGQHNYD P+QWMAC NKGYY+EIPSIGAIR
Sbjct: 400 TDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIR 459
Query: 421 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK 480
INTQEYLDVLGRPMVLAG +AKQVQWTNVY DAL LGLV+TGTLPVFN+T + K
Sbjct: 460 INTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQ--DGPGEKK 517
Query: 481 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL 540
NQLILGVMG+DV+L DIKRLTP +TL NGY FAID NGYVLLHPNL+P+ +EPVTL
Sbjct: 518 NQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTL 577
Query: 541 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL 600
DFLDAELE++ K EIR MIDG G K RTLVKS DERYID+ R YTW P+ T+YSL
Sbjct: 578 DFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTRNYTWVPIRSTNYSL 637
Query: 601 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI 660
LVLP YS +Y++A L + I Q +K E L P +FE G+ FIAPR+YC DL
Sbjct: 638 GLVLPPYSTFYLQANLSDQILQ-------VKYFEFLLPSSFESEGHVFIAPREYCKDLNA 690
Query: 661 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQK-NIKGVKA 719
SDNNTEFL NF E +++ TP++ CN L++ ++LD G T +LV+ W Q N + A
Sbjct: 691 SDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLA 750
Query: 720 RFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNK-SGPGAYES 778
F TDGGITRV+P +A E+W ENPE + SFY+RSLDN YVF P+ + P E+
Sbjct: 751 VFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDALLRPLELEN 810
Query: 779 ---GIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENF-----TKTSIRDP-CAGP---- 825
GI+VS AVE+ + + L+PAVVG+K+D+ +W E F +T P GP
Sbjct: 811 DTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPNSHC 870
Query: 826 VCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKS 885
DC+ N++ + CV++DDGGFL+++N + +Q+GRFF E+D +LM L N S Y +S
Sbjct: 871 EMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKES 930
Query: 886 YDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEA 945
YDYQ+ C P GA R +VP+VAD L + WW +AAAWS+ QQ L L + +A
Sbjct: 931 YDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQA 990
Query: 946 VEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIM 1005
E + + + SC+ +QTQY+F + + S++ ++DCGNCSR+FH ++L NTNL+F++
Sbjct: 991 DPAEAEG-SPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVV 1049
Query: 1006 VESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGL 1065
E C+ L+Q E SDGP C++V++PRYR+GP +CFD N ED +DCG +
Sbjct: 1050 AEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASF 1109
Query: 1066 NPSLWYIIGIQFLLL 1080
PSL ++ +Q LLL
Sbjct: 1110 PPSLGVLVSLQLLLL 1124
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta subunit
2 isoform a [Homo sapiens]
Length = 1145
Score = 1166 bits (3017), Expect = 0.0
Identities = 594/1097 (54%), Positives = 768/1097 (70%), Gaps = 37/1097 (3%)
Query: 7 LALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQD 66
L L L L L +S FP T++ W ++++++ + + GV QL +IY+ ++
Sbjct: 44 LWLLLPLLPLLAAPGASAYSFPQQHTMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRN 103
Query: 67 LYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYN 126
L+ V+ N ++LVE A DIE LL + +AL RLA AE Q AH+W+++ ++VYY+
Sbjct: 104 LFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYD 163
Query: 127 AKDDL---DPEKNDSEPGSQR--IKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLN 181
AK D DPE D E GS+ ++ FIED NF +++Y +AAV IPTDIY+GST++LN
Sbjct: 164 AKADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILN 223
Query: 182 ELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRR 241
ELNWT AL+ VF +NR +DP+LLWQVFGSATG+ RYYPA+PW R P KIDLYDVRRR
Sbjct: 224 ELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATPW----RAPKKIDLYDVRRR 279
Query: 242 PWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDV 301
PWYIQGA+SPKDM+I+VDVSGSVSGLTLKL++TSV EML+TLSDDD+VNVASFN AQ V
Sbjct: 280 PWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPV 339
Query: 302 SCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLF 361
SCF HLVQANVRNKKV K+AV + AKG T YK GF +AF+QL N N++RANCNK+IM+F
Sbjct: 340 SCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMF 399
Query: 362 TDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR 420
TDGGE+R Q++F KYN ++ VRVFTFSVGQHNYD P+QWMAC NKGYY+EIPSIGAIR
Sbjct: 400 TDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIR 459
Query: 421 INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLK 480
INTQEYLDVLGRPMVLAG +AKQVQWTNVY DAL LGLV+TGTLPVFN+T + K
Sbjct: 460 INTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQ--DGPGEKK 517
Query: 481 NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTL 540
NQLILGVMG+DV+L DIKRLTP +TL NGY FAID NGYVLLHPNL+P+ +EPVTL
Sbjct: 518 NQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTL 577
Query: 541 DFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSL 600
DFLDAELE++ K EIR MIDG G K RTLVKS DERYID+ R YTW P+ T+YSL
Sbjct: 578 DFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTRNYTWVPIRSTNYSL 637
Query: 601 ALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKI 660
LVLP YS +Y++A L + I Q +K E L P +FE G+ FIAPR+YC DL
Sbjct: 638 GLVLPPYSTFYLQANLSDQILQ-------VKYFEFLLPSSFESEGHVFIAPREYCKDLNA 690
Query: 661 SDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQK-NIKGVKA 719
SDNNTEFL NF E +++ TP++ CN L++ ++LD G T +LV+ W Q N + A
Sbjct: 691 SDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLA 750
Query: 720 RFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNK-SGPGAYES 778
F TDGGITRV+P +A E+W ENPE + SFY+RSLDN YVF P+ + P E+
Sbjct: 751 VFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDALLRPLELEN 810
Query: 779 ---GIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENF-----TKTSIRDP-CAGP---- 825
GI+VS AVE+ + + L+PAVVG+K+D+ +W E F +T P GP
Sbjct: 811 DTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPNSHC 870
Query: 826 VCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKS 885
DC+ N++ + CV++DDGGFL+++N + +Q+GRFF E+D +LM L N S Y +S
Sbjct: 871 EMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKES 930
Query: 886 YDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEA 945
YDYQ+ C P GA R +VP+VAD L + WW +AAAWS+ QQ L L + +A
Sbjct: 931 YDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQA 990
Query: 946 VEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIM 1005
E + + + SC+ +QTQY+F + + S++ ++DCGNCSR+FH ++L NTNL+F++
Sbjct: 991 DPAEAEG-SPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVV 1049
Query: 1006 VESKGTCPCDTRLLIQAEQ--TSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVS 1063
E C+ L+Q E +DGP C++V++PRYR+GP +CFD N ED +DCG +
Sbjct: 1050 AEKPLCSQCEAGRLLQKETHCPADGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGA 1109
Query: 1064 GLNPSLWYIIGIQFLLL 1080
PSL ++ +Q LLL
Sbjct: 1110 SFPPSLGVLVSLQLLLL 1126
>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
Length = 1091
Score = 401 bits (1030), Expect = e-111
Identities = 319/1122 (28%), Positives = 546/1122 (48%), Gaps = 121/1122 (10%)
Query: 3 AGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYE 62
A LLA L L+ +L SE+ P +V +K W ++ ++A SG L Y+
Sbjct: 14 ASALLAAAL-LYAALGDVVRSEQQIPLSV-VKLWASAFGGEIKSIAAKYSGSQLLQKKYK 71
Query: 63 KYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEV 122
+Y+ +E + QLV+ A+++E++ +S+A+ RL AE+ H++ D +
Sbjct: 72 EYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADL---QY 128
Query: 123 VYYNAK--DDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL 180
Y+NA ++ D + N E G + I N IS V +PT++Y ++
Sbjct: 129 EYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSD--VQVPTNMYNKDPAIV 186
Query: 181 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR 240
N + W+ +L++VF N + DPSL+WQ FGSA G R YP W + N + +D R
Sbjct: 187 NGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDE---NGVIAFDCRN 243
Query: 241 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD 300
R WYIQ A SPKD++ILVDVSGS+ GL L + + +VS +L+TL DDDF N+ ++N
Sbjct: 244 RKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHY 303
Query: 301 VS-CFQ-HLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRAN--CNK 356
V C LVQA+ NK+ ++ ++ + AKGI + AF L ++N + C++
Sbjct: 304 VEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQ 363
Query: 357 IIMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPS 415
IML TDG + IF KYN D+KVR+FT+ +G+ ++WMAC NKG++ +I +
Sbjct: 364 AIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQIST 423
Query: 416 IGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDAL---------ELG--LVITGTL 464
+ ++ N EYL VL RP V+ D+ V WT Y+D+ + G L+ T +
Sbjct: 424 LADVQENVMEYLHVLSRPKVI--DQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAM 481
Query: 465 PVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLH 524
PVF+ +N+T K ++LGV+G DV ++++ + P++ L +GY FAI NGY+L H
Sbjct: 482 PVFS----KQNETRSKG-ILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTH 536
Query: 525 PNLQ---PKNPKSQEP--VTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDER 579
P L+ + K ++P ++D + E E+ V +RN M++ ++G+ + ++
Sbjct: 537 PELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDV-LRNAMVNRKTGKFSMEV------KK 589
Query: 580 YIDKGNRT------YTWTPVNGTDYSLALVLPT-YSFYYIKAKLEETITQARSKKGKMKD 632
+DKG R Y +T + GT +SL + L + Y+ +G +
Sbjct: 590 TVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFF--------------RGNVTI 635
Query: 633 SETLKPDNFEESGYTFIAPRDYCN-DLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLIN 691
E L + E + YCN DL + L ++ K P C+ +LI
Sbjct: 636 EEGL--HDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEP-LLQCDKELIQ 692
Query: 692 RVLLDAGFTNELVQNYWS------KQKNIKGVKARFVVTDGGITRVYP------------ 733
VL DA + ++ YW+ + + KGV+ F+ T G++R+
Sbjct: 693 EVLFDA-VVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDF 751
Query: 734 KEAGENWQENPETYEDSFYKRSLDN--DNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQ 791
+AG+ + +Y+R+ + ++V++ P+ +GP + + S ++++ +
Sbjct: 752 LKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPF--STGPVNKSNVVTASTSIQLLDE 809
Query: 792 GKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMAN 851
K A VGI++ + + F S + C + + ++C ++D+ GF+L++
Sbjct: 810 RKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVS- 868
Query: 852 HDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPS 911
+DYT Q G FFGEI+ ++M L+ + + YDYQ++C GA P
Sbjct: 869 -EDYT-QTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGA--HGLLDPY 924
Query: 912 VADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSK-----QSCITEQ 966
A + + W T +++ L S D TA K + C TE
Sbjct: 925 NAFLSAVKWIMTELVLFLVEFNLCS-----------WWHSDMTAKAQKLKQTLEPCDTEY 973
Query: 967 TQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTS 1026
+ + K +G + C +CS+ F +++ ++NL ++V+S +C C++ I
Sbjct: 974 PAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDS--SCLCESVAPITMAPIE 1031
Query: 1027 DGPN---PCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGL 1065
N C+ +K + R+ P+ C + E+ +CGG L
Sbjct: 1032 IRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSL 1073
>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
[Homo sapiens]
Length = 1137
Score = 394 bits (1012), Expect = e-109
Identities = 320/1128 (28%), Positives = 535/1128 (47%), Gaps = 128/1128 (11%)
Query: 10 TLTLFQSLLIGPSSEEPFPSAV----TIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQ 65
T L LL+G S + A T+K W D DL SG L Y+ +
Sbjct: 50 TSALLWLLLLGTSLSPAWGQAKIPLETVKLWADTFGGDLYNTVTKYSGSLLLQKKYKDVE 109
Query: 66 DLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYY 125
+E + +LV + D+E +L + +A+ L AE+ H++ E + YY
Sbjct: 110 SSLKIEEVDGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFNESLVFD---YY 166
Query: 126 NAK--DDLDPEKNDSEPGSQRIKPVFIEDANFGR-QISYQHAAVHIPTDIYEGSTIVLNE 182
N+ ++ D + N E G++ + +A+F ++ ++V +PT++Y +LN
Sbjct: 167 NSVLINERDEKGNFVELGAEFLLE---SNAHFSNLPVNTSISSVQLPTNVYNKDPDILNG 223
Query: 183 LNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRP 242
+ + AL+ VF +N + DP+L WQ FGSATG R YP W + N + +D R R
Sbjct: 224 VYMSEALNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDE---NGVITFDCRNRG 280
Query: 243 WYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVS 302
WYIQ A SPKD++ILVDVSGS+ GL + + + +++ +L+TL ++DF+N+ ++N +
Sbjct: 281 WYIQAATSPKDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIE 340
Query: 303 -CFQH-LVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRAN--CNKII 358
CF+ LVQA+ N++ K V + KG+ + AF+ L + ++ CN+ I
Sbjct: 341 PCFKGILVQADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAI 400
Query: 359 MLFTDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIG 417
ML +DG E + +F KYN D KVRVFT+ +G+ ++W+AC NKGYY +I ++
Sbjct: 401 MLISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLA 460
Query: 418 AIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLD-------ALELGLVITGTLPVFNIT 470
+ N EYL VL RPMV+ D + WT Y+D A L L+ T +PVF+
Sbjct: 461 DTQENVMEYLHVLSRPMVINHD--HDIIWTEAYMDSKLLSSQAQSLTLLTTVAMPVFS-- 516
Query: 471 GQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQP- 529
+N+T + ++LGV+G DV+L ++ +L PR+ L +GY F NGY+L HP+L+P
Sbjct: 517 --KKNETR-SHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPL 573
Query: 530 -KNPKSQEPV----TLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKG 584
+ K +P ++D + E E+ + +R MI+ E+G + V +DKG
Sbjct: 574 YREGKKLKPKPNYNSVDLSEVEWEDQAE-SLRTAMINRETGTLSMDVKVP------MDKG 626
Query: 585 NRT------YTWTPVNGTDYSLALVLPTYSFYYI---KAKLEETITQARSKKGKMKDSET 635
R Y +T ++ T +SL +VL YI +EE + +
Sbjct: 627 KRVLFLTNDYFFTDISDTPFSLGVVLSRGHGEYILLGNTSVEEGL------------HDL 674
Query: 636 LKPDNFEESGYTFIAPRDYC-NDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVL 694
L PD YC D+ L F+ RK P + C+ +L+ VL
Sbjct: 675 LHPD------LALAGDWIYCITDIDPDHRKLSQLEAMIRFLTRKDP-DLECDEELVREVL 727
Query: 695 LDAGFTNELVQNYWS------KQKNIKGVKARFVVTDGGITR----VYPKEAGENWQENP 744
DA T + + YW+ +++ V F+ T G+ R V ++ + P
Sbjct: 728 FDAVVTAPM-EAYWTALALNMSEESEHVVDMAFLGTRAGLLRSSLFVGSEKVSDRKFLTP 786
Query: 745 ETYEDSF--------YKRSLDN--DNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKL 794
E F Y+++ ++ ++VF + + S AV + + +
Sbjct: 787 EDEASVFTLDRFPLWYRQASEHPAGSFVFNLRWAEGPESAGEPMVVTASTAVAVTVDKRT 846
Query: 795 LKPAVVGIKIDVNSWIENF-TKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHD 853
A G+++ + F T GP +SD +DC ++D+ GF+L++
Sbjct: 847 AIAAAAGVQMKLEFLQRKFWAATRQCSTVDGPCTQSCEDSD-LDCFVIDNNGFILISKR- 904
Query: 854 DYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVA 913
+ + GRF GE+D +++ L+++ V++ YDYQ++C+P + H SA P V+
Sbjct: 905 --SRETGRFLGEVDGAVLTQLLSMGVFSQVTMYDYQAMCKP------SSHHHSAAQPLVS 956
Query: 914 DILQIGWWATAAAWSILQQFLLSLT--------FPRLLEA--VEMEDDDFTASLSKQSCI 963
I + TA W +LQ+ +L L + R EA V Q C
Sbjct: 957 ---PISAFLTATRW-LLQELVLFLLEWSVWGSWYDRGAEAKSVFHHSHKHKKQDPLQPCD 1012
Query: 964 TEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAE 1023
TE + + + +G+++CG C ++F +++ N+NL+ ++ + TC C + E
Sbjct: 1013 TEYPVFVYQPAIREANGIVECGPCQKVFVVQQIPNSNLLLLVTDP--TCDCSIFPPVLQE 1070
Query: 1024 QTSDGPN---PCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPS 1068
T N CD ++ + R+ PD C + E+ DCGG S + S
Sbjct: 1071 ATEVKYNASVKCDRMRSQKLRRRPDSCHAFHPEENAQDCGGASDTSAS 1118
>gi|110578649 cache domain containing 1 [Homo sapiens]
Length = 1223
Score = 97.8 bits (242), Expect = 5e-20
Identities = 159/763 (20%), Positives = 310/763 (40%), Gaps = 104/763 (13%)
Query: 145 IKPVFIE-DANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSL 203
I P +E D NF +S + + T T+ N L+ V N + +P +
Sbjct: 80 IPPSMMEFDGNFNTNVSRTISCDRLST------TVNSRAFNPGRDLNSVLADNLKSNPGI 133
Query: 204 LWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAA-SPKDMLILVDVSG 262
WQ F S G+ +PA + Y+ R RP Y+ K +++++D
Sbjct: 134 KWQYFSSEEGIFTVFPAHKFRCKGS-------YEHRSRPIYVSTVRPQSKHIVVILDHGA 186
Query: 263 SVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVS---CFQ-HLVQANVRNKKVL 318
SV+ L++ + + +L + + D ++V + + S C++ L A K+ +
Sbjct: 187 SVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKM 246
Query: 319 KDAVNNI-TAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFT------DGGEER 368
V+++ ++ T + GF AF+ + + N + +AN + +I+ + D EE
Sbjct: 247 STFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEED 306
Query: 369 AQ---EIFNKYNK--DKKVRVFTFSVGQHNY----DRGPIQWMACENKGYY-----YEIP 414
+ ++ N+ N + V + T+++ + ++ +A +N G Y +P
Sbjct: 307 KKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALP 366
Query: 415 SI-GAIRINTQ--EYLDVLGRPMV-LAGDKAKQVQWTNVYLDALELGLVITGTLPVFNIT 470
I G++ + Q +GR L + ++ + D + GL++T + P +
Sbjct: 367 VIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCY--- 423
Query: 471 GQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPK 530
F N L+LG++GVDV+L I + Y F ID GY L+HP+L
Sbjct: 424 --FGN-------LLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRP 474
Query: 531 NPKSQEPVTLDFLDAELENDIKVE-IRNKMIDGESGEKTFRTLVKSQDERYIDK------ 583
S+ P+ D + EN K E +R ++ G + V S +I+K
Sbjct: 475 YLLSEPPLHTDII--HYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGK 532
Query: 584 --GNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGKM----------- 630
N +Y W V T + L +V+ + K T+ ++ ++
Sbjct: 533 EAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLH 592
Query: 631 -KDSETLKPDNFEESGYTFIAPRDYCND---LKISDNNTEFLLNFNEFIDRKTPNNPSCN 686
K TL+ S +F +P ++ + ++ ++ T +L + I NP
Sbjct: 593 FKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLI-----ANPGLK 647
Query: 687 ADLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPET 746
+ N V+ + T+E + N V+ R++ T G+ R+YP G + +
Sbjct: 648 FSVRNEVMATSHVTDEWMTQMEMSSLNTYIVR-RYIATPNGVLRIYP---GSLMDKAFDP 703
Query: 747 YEDSFYKRSLDNDNYV-FTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKID 805
+Y ++ N + T PY + G +G +V+ + I+ L +
Sbjct: 704 TRRQWYLHAVANPGLISLTGPYLDVGG-----AGYVVTISHTIHSSSTQLSSGHTVAVMG 758
Query: 806 VNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLL 848
++ + F K + PVC+ + + + C I++D G+L+
Sbjct: 759 IDFTLRYFYKVLMD---LLPVCN-QDGGNKIRCFIMEDRGYLV 797
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 60.8 bits (146), Expect = 7e-09
Identities = 48/195 (24%), Positives = 98/195 (50%), Gaps = 14/195 (7%)
Query: 251 PKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCF-QHLVQ 309
PK++ ++D+SGS++G L+ + ++ +LE + ++D++N F+ DVS + +HLVQ
Sbjct: 282 PKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSG---DVSTWKEHLVQ 338
Query: 310 ANVRNKKVLKDAVNNITAKGITDYK----KGFSFAFEQLLNYNVSRANCNKIIMLFTDG- 364
A N + + V ++ KG+T+ +G S + + + + + +IML TDG
Sbjct: 339 ATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIML-TDGD 397
Query: 365 ---GEERAQEIFNKYNKDKKVRVFTFSVG-QHNYDRGPIQWMACENKGYYYEIPSIGAIR 420
GE R ++I + +++G +N + ++ MA EN G+ I
Sbjct: 398 ANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDAD 457
Query: 421 INTQEYLDVLGRPMV 435
+ Q + + + P++
Sbjct: 458 LQLQGFYEEVANPLL 472
>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
sapiens]
Length = 946
Score = 47.4 bits (111), Expect = 8e-05
Identities = 71/354 (20%), Positives = 142/354 (40%), Gaps = 41/354 (11%)
Query: 251 PKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQA 310
PK++L ++DVSGS+ G+ +K ++ +L+ L +D +V FN N + + L+ A
Sbjct: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR--TWRNDLISA 365
Query: 311 NVRNKKVLKDAVNNITAKGITDYKKGF---SFAFEQLLNYNVSRANCNKIIMLFTDG--- 364
K + I G T+ + F + N + N +I+L +DG
Sbjct: 366 TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPT 425
Query: 365 -GEERAQEIFNKYNKDKKVRVFTFSVGQ-HNYDRGPIQWMACENKGYYYEIPSIGAIRIN 422
GE + +I ++ + + FS+G + D ++ ++ EN G I
Sbjct: 426 VGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQ 485
Query: 423 TQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALEL------------GLVITGTLPVFNIT 470
+++ + + P++ + VQ+ + ++ +V+ G +
Sbjct: 486 LKKFYNQVSTPLL------RNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKL- 538
Query: 471 GQFEN---KTNLKNQLILGVMGVDVSLEDI----KRLTPRFTLCPNGYYFAIDPNGYVLL 523
Q E+ T+ QL+L + L+D K P FT +A +L
Sbjct: 539 DQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFT----RKLWAYLTINQLLA 594
Query: 524 HPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQD 577
+L P ++ +T L L++ I + + +I+ E+G++ QD
Sbjct: 595 ERSLAP-TAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQD 647
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 47.0 bits (110), Expect = 1e-04
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 10/195 (5%)
Query: 251 PKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQA 310
PK+++ ++D SGS+SG ++ R ++ ++L+ LS D N+ F++ A LV A
Sbjct: 272 PKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEA--TQWRPSLVPA 329
Query: 311 NVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSR---ANCNKIIMLFTDG--- 364
+ N + I A G T+ A + L + N +I+L TDG
Sbjct: 330 SAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPT 389
Query: 365 -GEERAQEIFNKYNKDKKVRVFTFSVG-QHNYDRGPIQWMACENKGYYYEIPSIGAIRIN 422
GE + I N + R F +G + ++ +A +N G I +
Sbjct: 390 VGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQ 449
Query: 423 TQEYLDVLGRPMVLA 437
Q++ + P++ A
Sbjct: 450 LQDFYQEVANPLLTA 464
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/197 (22%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 252 KDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQAN 311
K+++ ++D+SGS+ G +K + ++ ++L + D+ ++ F + Q S LVQA+
Sbjct: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ--SWKGSLVQAS 348
Query: 312 VRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFTDGG--- 365
N + +D V + T+ G E L S +N I+++ TDG
Sbjct: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTE 408
Query: 366 --EERAQEIFNKYNKDK-KVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRIN 422
+R+Q + N N + + ++ G HN D ++ M+ EN G I
Sbjct: 409 GVTDRSQILKNVRNAIRGRFPLYNLGFG-HNVDFNFLEVMSMENNGRAQRIYEDHDATQQ 467
Query: 423 TQEYLDVLGRPMVLAGD 439
Q + + +P+++ D
Sbjct: 468 LQGFYSQVAKPLLVDVD 484
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 42.7 bits (99), Expect = 0.002
Identities = 27/97 (27%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 252 KDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQAN 311
K+++ ++DVS S+ G ++ +T+++ +L L +D+ N+ SF S+ +V +QA
Sbjct: 282 KNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISF-SDTVNVWKAGGSIQAT 340
Query: 312 VRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYN 348
++N KD ++ + A G TD A +LN++
Sbjct: 341 IQNVHSAKDYLHCMEADGWTDVNSAL-LAAASVLNHS 376
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 14/171 (8%)
Query: 247 GAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQH 306
G +S D++ L+D S SV +L++ +S++++TL D +A S Q
Sbjct: 269 GGSSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSD--KLAQVGLVQYSSSVRQE 326
Query: 307 LVQANVRNKKVLKDAVNNIT--AKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLF 361
KK +K AV N++ KG G + + ++ VS R K+ ++F
Sbjct: 327 FPLGRFHTKKDIKAAVRNMSYMEKGT---MTGAALKYLIDNSFTVSSGARPGAQKVGIVF 383
Query: 362 TDGGEERAQEIFNKYNKDKKVRVF-TFSVGQHNYDRGPIQWMACENKGYYY 411
TDG R+Q+ N K K F F+VG N ++ +A E +Y
Sbjct: 384 TDG---RSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHY 431
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 39.7 bits (91), Expect = 0.016
Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 10/157 (6%)
Query: 253 DMLILVDVSGSVSGLTLKLIRTSVSEMLETLS-DDDFVNVASFNSNAQDVSCFQHLVQAN 311
D+++LVD S S+ + +R+ +S ++E V +A + + +Q + A+
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQ--LNAH 92
Query: 312 VRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFTDGGEER 368
R+KK L AV N+ KG + G + F + N+ R KI +L TDG +
Sbjct: 93 -RDKKSLLQAVANLPYKG-GNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQD 150
Query: 369 AQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACE 405
E +K KD+ V + F++G N D ++ +A +
Sbjct: 151 DVEAPSKKLKDEGVEL--FAIGIKNADEVELKMIATD 185
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 39.7 bits (91), Expect = 0.016
Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 10/157 (6%)
Query: 253 DMLILVDVSGSVSGLTLKLIRTSVSEMLETLS-DDDFVNVASFNSNAQDVSCFQHLVQAN 311
D+++LVD S S+ + +R+ +S ++E V +A + + +Q + A+
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQ--LNAH 1256
Query: 312 VRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFTDGGEER 368
R+KK L AV N+ KG + G + F + N+ R KI +L TDG +
Sbjct: 1257 -RDKKSLLQAVANLPYKG-GNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQD 1314
Query: 369 AQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACE 405
E +K KD+ V + F++G N D ++ +A +
Sbjct: 1315 DVEAPSKKLKDEGVEL--FAIGIKNADEVELKMIATD 1349
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 38.1 bits (87), Expect = 0.046
Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 18/196 (9%)
Query: 210 SATGLARYYPASPWVDNSRTPNKIDLYD--VRRRPWYIQGAASPKDMLILVDVSGSVSGL 267
+A G PA P + ++++ RRR ++ + +++ LVD S SV +
Sbjct: 38 TAPGAPGSIPAPPAPGDEAAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEV 97
Query: 268 TLKLIRTSVSEMLE---TLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKK--VLKDAV 322
+ V ++L + V + +F+S V ++ R K +L +
Sbjct: 98 NFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEI 157
Query: 323 NNITAKGITDYKKG-FSFAFEQLLNYNVSRANCNKIIMLFTD----GGEERAQEIFNKYN 377
I+ +G Y KG F A + LL+ +R N K++ L TD GG+ R
Sbjct: 158 PAISYRGGGTYTKGAFQQAAQILLH---ARENSTKVVFLITDGYSNGGDPRP---IAASL 211
Query: 378 KDKKVRVFTFSVGQHN 393
+D V +FTF + Q N
Sbjct: 212 RDSGVEIFTFGIWQGN 227
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 35.8 bits (81), Expect = 0.23
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 251 PKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLS---DDDFVNVASFNSNAQDVSCFQHL 307
P D++ ++D S SV L ++T VS +++TL D V V ++ S + +
Sbjct: 81 PLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVK----IEFQ 136
Query: 308 VQANVRNKKVLKDAVNNITAKGITDYKKGFSF------AFEQLLNYNVSRANCNKIIMLF 361
+QA +K+ LK AV IT T G + AF +N K+ ++
Sbjct: 137 LQA-YTDKQSLKQAVGRITPLS-TGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIV 194
Query: 362 TDGGEERAQEIFNKY-NKDKKVRVFTFSVGQHNYDRGPIQWMACE 405
TDG R Q+ N+ + + + ++VG D ++ MA E
Sbjct: 195 TDG---RPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASE 236
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 34.7 bits (78), Expect = 0.51
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 12/158 (7%)
Query: 253 DMLILVDVSGSVSGLTLKLIRTSVSEMLETL---SDDDFVNVASFNSNAQDVSCFQHLVQ 309
D++ILVD S S+ +L+R + ++ S+ + +A ++ D HL
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSG---DPRIEWHLNA 214
Query: 310 ANVRNKKVLKDAVNNITAK-GITDYKKGFSFAFEQLLNYNV-SRANCNKIIMLFTDGGEE 367
+ +++ + +AV N+ K G T ++ FE SR +KI +L TDG +
Sbjct: 215 FSTKDEVI--EAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQ 272
Query: 368 RAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACE 405
+I ++ V F++G N D +Q +A E
Sbjct: 273 --DDIIPPSRNLRESGVELFAIGVKNADVNELQEIASE 308
>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
Length = 292
Score = 34.3 bits (77), Expect = 0.66
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 22/108 (20%)
Query: 554 EIRNKMIDGESGEKTFRTLVKSQDERY----IDKGNRTYTWTPVNGTDYSLALVLPTYSF 609
E+ +M D G K R ++ S R D+ ++ Y W P N
Sbjct: 35 ELEKQMEDAYRGTK--RKMLPSSSSRMRSDGFDEESQRYYWRPKNE-------------- 78
Query: 610 YYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCND 657
I LE+ +A+S K D E PD + SGY + P ++ D
Sbjct: 79 --ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETD 124
>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 34.3 bits (77), Expect = 0.66
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 22/108 (20%)
Query: 554 EIRNKMIDGESGEKTFRTLVKSQDERY----IDKGNRTYTWTPVNGTDYSLALVLPTYSF 609
E+ +M D G K R ++ S R D+ ++ Y W P N
Sbjct: 35 ELEKQMEDAYRGTK--RKMLPSSSSRMRSDGFDEESQRYYWRPKNE-------------- 78
Query: 610 YYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCND 657
I LE+ +A+S K D E PD + SGY + P ++ D
Sbjct: 79 --ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETD 124
>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 34.3 bits (77), Expect = 0.66
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 22/108 (20%)
Query: 554 EIRNKMIDGESGEKTFRTLVKSQDERY----IDKGNRTYTWTPVNGTDYSLALVLPTYSF 609
E+ +M D G K R ++ S R D+ ++ Y W P N
Sbjct: 35 ELEKQMEDAYRGTK--RKMLPSSSSRMRSDGFDEESQRYYWRPKNE-------------- 78
Query: 610 YYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCND 657
I LE+ +A+S K D E PD + SGY + P ++ D
Sbjct: 79 --ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETD 124
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 18/161 (11%)
Query: 251 PKDMLILVDVSGSVSGLTLKLIR---TSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHL 307
P DM+ LVD S S+ + ++ SV E D V + ++ +AQ L
Sbjct: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236
Query: 308 VQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVS-----RANCNKIIMLFT 362
K+ + AV + KG + A +L N+ R K+++L T
Sbjct: 237 -----STKEQVLAAVRRLRYKGGNTFT---GLALTHVLGQNLQPAAGLRPEAAKVVILVT 288
Query: 363 DGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMA 403
DG + + KD V V F+VG N D ++ +A
Sbjct: 289 DGKSQDDVHTAARVLKDLGVNV--FAVGVKNADEAELRLLA 327
>gi|239787094 A20-binding inhibitor of NF-kappaB activation 2
isoform 2 [Homo sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 3.3
Identities = 34/158 (21%), Positives = 68/158 (43%), Gaps = 19/158 (12%)
Query: 21 PSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKY---QDLYTV------- 70
P E +++S ++K+QE+ L + + V L +++Y +D Y
Sbjct: 80 PDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLR 139
Query: 71 ------EPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVY 124
EP R+ + R +E+ +++ ++ LA AA + R +++
Sbjct: 140 GLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALE-RVQMLEQQILA 198
Query: 125 YNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQ 162
Y KDD E+ D E RI+ + + A+ Q+S++
Sbjct: 199 Y--KDDFMSERADRERAQSRIQELEEKVASLLHQVSWR 234
>gi|239787092 A20-binding inhibitor of NF-kappaB activation 2
isoform 1 [Homo sapiens]
Length = 429
Score = 32.0 bits (71), Expect = 3.3
Identities = 34/158 (21%), Positives = 68/158 (43%), Gaps = 19/158 (12%)
Query: 21 PSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKY---QDLYTV------- 70
P E +++S ++K+QE+ L + + V L +++Y +D Y
Sbjct: 187 PDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLR 246
Query: 71 ------EPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVY 124
EP R+ + R +E+ +++ ++ LA AA + R +++
Sbjct: 247 GLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALE-RVQMLEQQILA 305
Query: 125 YNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQ 162
Y KDD E+ D E RI+ + + A+ Q+S++
Sbjct: 306 Y--KDDFMSERADRERAQSRIQELEEKVASLLHQVSWR 341
>gi|33469964 splicing factor 4 [Homo sapiens]
Length = 645
Score = 32.0 bits (71), Expect = 3.3
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 61 YEKYQDLYTVEPNNA--RQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFA 118
YE++ ++ P A R+++E AR ++ L ++A+E K A + D
Sbjct: 172 YEQWLEIKVSPPEGAETRKVIEKLAR----FVAEGGPELEKVAMEDYKDNPAFAFLHDKN 227
Query: 119 SNEVVYYNAK-DDLDPEKNDSEPGSQRIKP 147
S E +YY K ++ E S+ SQ++ P
Sbjct: 228 SREFLYYRKKVAEIRKEAQKSQAASQKVSP 257
>gi|122937404 membrane bound O-acyltransferase domain containing 1
[Homo sapiens]
Length = 495
Score = 32.0 bits (71), Expect = 3.3
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 8/71 (11%)
Query: 283 LSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKK----VLKDAVNNITAKGITDYKKGFS 338
L DD FV+ ASF + C+ ++V + K L DAVNN G + K +
Sbjct: 267 LVDDWFVHKASFPARL----CYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGN 322
Query: 339 FAFEQLLNYNV 349
F ++ L N N+
Sbjct: 323 FCWDLLSNLNI 333
>gi|20127561 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11,
17.3kDa isoform 1 [Homo sapiens]
Length = 163
Score = 31.6 bits (70), Expect = 4.3
Identities = 13/43 (30%), Positives = 23/43 (53%)
Query: 719 ARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNY 761
+R VV + P E WQE+PE +++ Y+++ D+ Y
Sbjct: 34 SRTVVAPSAVAGKRPPEPTTPWQEDPEPEDENLYEKNPDSHGY 76
>gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11,
17.3kDa isoform 2 [Homo sapiens]
Length = 153
Score = 31.6 bits (70), Expect = 4.3
Identities = 13/43 (30%), Positives = 23/43 (53%)
Query: 719 ARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNY 761
+R VV + P E WQE+PE +++ Y+++ D+ Y
Sbjct: 34 SRTVVAPSAVAGKRPPEPTTPWQEDPEPEDENLYEKNPDSHGY 76
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 30.8 bits (68), Expect = 7.3
Identities = 28/149 (18%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 253 DMLILVDVSGSVSGLTLKLIRTSVSEMLETLS---DDDFVNVASFNSNAQD---VSCFQH 306
D++ ++D S SV+ ++ + ++L+ L D V + + S ++ + F+
Sbjct: 57 DLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKR 116
Query: 307 LVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGE 366
+ K++ + +T I + + AF + R N ++IM+ TDG
Sbjct: 117 KSEVERAVKRMRHLSTGTMTGLAI---QYALNIAFSEAEGARPLRENVPRVIMIVTDGRP 173
Query: 367 ERAQEIFNKYNKDKKVRVFTFSVGQHNYD 395
+ + +D + +F VGQ +++
Sbjct: 174 QDSVAEVAAKARDTGILIFAIGVGQVDFN 202
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 30.8 bits (68), Expect = 7.3
Identities = 28/149 (18%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 253 DMLILVDVSGSVSGLTLKLIRTSVSEMLETLS---DDDFVNVASFNSNAQD---VSCFQH 306
D++ ++D S SV+ ++ + ++L+ L D V + + S ++ + F+
Sbjct: 57 DLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKR 116
Query: 307 LVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGE 366
+ K++ + +T I + + AF + R N ++IM+ TDG
Sbjct: 117 KSEVERAVKRMRHLSTGTMTGLAI---QYALNIAFSEAEGARPLRENVPRVIMIVTDGRP 173
Query: 367 ERAQEIFNKYNKDKKVRVFTFSVGQHNYD 395
+ + +D + +F VGQ +++
Sbjct: 174 QDSVAEVAAKARDTGILIFAIGVGQVDFN 202
>gi|197209974 coiled-coil and C2 domain containing 2A isoform a
[Homo sapiens]
Length = 1620
Score = 30.8 bits (68), Expect = 7.3
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 21/143 (14%)
Query: 307 LVQANVRNKKVLK--DAVNNITAKGITDYKKGFSFAFEQLLNYN-VSRANCNKIIMLFTD 363
L Q N+ + LK DA+++I G+TD KK +A E L+ N + A ++I + T
Sbjct: 820 LSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATS 879
Query: 364 GGE--------ERAQEIFN-----KYNKDKKVRVFTFSVGQ----HNYDRGPIQWMACEN 406
G E+ Q+ FN + N+ K+ R+ + NY + P+
Sbjct: 880 GESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVPVYDREIME 939
Query: 407 KGYY-YEIPSIGAIRINTQEYLD 428
K + YE I T+E++D
Sbjct: 940 KVFQDYEKRLRDRNVIETKEHID 962
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,958,640
Number of Sequences: 37866
Number of extensions: 1843793
Number of successful extensions: 4386
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 4318
Number of HSP's gapped (non-prelim): 44
length of query: 1091
length of database: 18,247,518
effective HSP length: 113
effective length of query: 978
effective length of database: 13,968,660
effective search space: 13661349480
effective search space used: 13661349480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.