Guide to the Human Genome
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Name: CACNA2D2 Sequence: fasta or formatted (1145aa) NCBI GI: 54112392
Description:

calcium channel, voltage-dependent, alpha 2/delta subunit 2 isoform a

Referenced in:

Calcium and TRP Cation Channels
Common Drug Targets

Other entries for this name:
alt prot [1143aa] calcium channel, voltage-dependent, alpha 2/delta subunit 2 isofo...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         84           3
 C cysteine            1.9         22           1
 D aspartate           6.0         69           3
 E glutamate           6.1         70           2
 F phenylalanine       4.3         49           2
 G glycine             6.0         69           2
 H histidine           1.7         20           1
 I isoleucine          3.5         40           2
 K lysine              4.5         51           2
 L leucine            10.5        120           5
 M methionine          1.7         19           2
 N asparagine          6.0         69           2
 P proline             6.1         70           2
 Q glutamine           5.2         59           2
 R arginine            5.7         65           3
 S serine              5.2         60           2
 T threonine           5.3         61           2
 V valine              7.3         84           2
 W tryptophan          1.7         20           2
 Y tyrosine            3.8         44           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   calcium channel, voltage-dependent, alpha 2/delta su... 
CACNA2D2              0.994   calcium channel, voltage-dependent, alpha 2/delta su...
CACNA2D1              0.491   calcium channel, voltage-dependent, alpha 2/delta su...
CACNA2D4              0.178   voltage-gated calcium channel alpha(2)delta-4 subun...
CACNA2D3              0.172   calcium channel, voltage-dependent, alpha 2/delta 3 ...
CACHD1                0.034   cache domain containing 1 
ITIH3                 0.014   inter-alpha (globulin) inhibitor H3 preproprotein [...
ITIH1                 0.012   inter-alpha (globulin) inhibitor H1 
RYK                   0.009   RYK receptor-like tyrosine kinase isoform 2 
RYK                   0.009   RYK receptor-like tyrosine kinase isoform 1 
ITIH4                 0.009   inter-alpha (globulin) inhibitor H4 
ITIH5L                0.009   inter-alpha (globulin) inhibitor H5-like 
MATN1                 0.007   matrilin 1, cartilage matrix protein 
N4BP1                 0.006   Nedd4 binding protein 1 
ITIH2                 0.006   inter-alpha globulin inhibitor H2 polypeptide 
MATN3                 0.006   matrilin 3 precursor 
CPAMD8                0.005   C3 and PZP-like, alpha-2-macroglobulin domain conta...
ADAM23                0.005   ADAM metallopeptidase domain 23 preproprotein 
RNF215                0.005   ring finger protein 215 
GLT8D4                0.005   glycosyltransferase 8 domain containing 4 
C4orf48               0.004   hypothetical protein LOC401115 
LOC100286967          0.004   PREDICTED: hypothetical protein XP_002342247 
BBC3                  0.004   BCL2 binding component 3 isoform 1 
TAF4                  0.004   TBP-associated factor 4 
TNIP3                 0.003   TNFAIP3 interacting protein 3 
TNIP3                 0.003   TNFAIP3 interacting protein 3 
VARS2                 0.003   valyl-tRNA synthetase 2, mitochondrial 
METRNL                0.003   meteorin, glial cell differentiation regulator-like ...
SHANK3                0.003   SH3 and multiple ankyrin repeat domains 3 
ZKSCAN5               0.003   zinc finger with KRAB and SCAN domains 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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