Guide to the Human Genome
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Name: CACNA2D1 Sequence: fasta or formatted (1091aa) NCBI GI: 54112390
Description:

calcium channel, voltage-dependent, alpha 2/delta subunit 1

Referenced in:

Calcium and TRP Cation Channels
Common Drug Targets

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         67           3
 C cysteine            1.8         20           1
 D aspartate           7.1         78           3
 E glutamate           5.9         64           2
 F phenylalanine       4.5         49           2
 G glycine             5.9         64           2
 H histidine           1.0         11           1
 I isoleucine          5.9         64           2
 K lysine              6.3         69           2
 L leucine             9.2        100           3
 M methionine          1.6         18           1
 N asparagine          6.9         75           2
 P proline             4.5         49           1
 Q glutamine           4.1         45           2
 R arginine            4.1         45           3
 S serine              6.7         73           2
 T threonine           5.4         59           1
 V valine              7.0         76           2
 W tryptophan          1.6         17           2
 Y tyrosine            4.4         48           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   calcium channel, voltage-dependent, alpha 2/delta su... 
CACNA2D2              0.523   calcium channel, voltage-dependent, alpha 2/delta su...
CACNA2D2              0.520   calcium channel, voltage-dependent, alpha 2/delta su...
CACNA2D3              0.171   calcium channel, voltage-dependent, alpha 2/delta 3 ...
CACNA2D4              0.168   voltage-gated calcium channel alpha(2)delta-4 subun...
CACHD1                0.033   cache domain containing 1 
ITIH3                 0.016   inter-alpha (globulin) inhibitor H3 preproprotein [...
ITIH2                 0.010   inter-alpha globulin inhibitor H2 polypeptide 
ITIH4                 0.010   inter-alpha (globulin) inhibitor H4 
ITIH1                 0.010   inter-alpha (globulin) inhibitor H1 
ITIH5L                0.008   inter-alpha (globulin) inhibitor H5-like 
MATN1                 0.007   matrilin 1, cartilage matrix protein 
COL12A1               0.007   collagen, type XII, alpha 1 short isoform precursor ...
COL12A1               0.007   collagen, type XII, alpha 1 long isoform precursor [...
SVEP1                 0.006   polydom 
MATN3                 0.005   matrilin 3 precursor 
COL14A1               0.005   collagen, type XIV, alpha 1 
C11orf57              0.004   hypothetical protein LOC55216 isoform b 
C11orf57              0.004   hypothetical protein LOC55216 isoform a 
C11orf57              0.004   hypothetical protein LOC55216 isoform a 
COL20A1               0.003   collagen, type XX, alpha 1 
TNIP2                 0.003   A20-binding inhibitor of NF-kappaB activation 2 iso...
TNIP2                 0.003   A20-binding inhibitor of NF-kappaB activation 2 iso...
SF4                   0.003   splicing factor 4 
MBOAT1                0.003   membrane bound O-acyltransferase domain containing ...
NDUFB11               0.003   NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1...
NDUFB11               0.003   NADH dehydrogenase (ubiquinone) 1 beta subcomplex, ...
MATN2                 0.003   matrilin 2 isoform b precursor 
MATN2                 0.003   matrilin 2 isoform a precursor 
CC2D2A                0.003   coiled-coil and C2 domain containing 2A isoform a [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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