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Search of human proteins with 51873053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
(1231 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 2648 0.0
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 2055 0.0
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 620 e-177
gi|34734066 fibulin 1 isoform D [Homo sapiens] 514 e-145
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 509 e-144
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 508 e-143
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 300 4e-81
gi|56237021 fibrillin 3 precursor [Homo sapiens] 299 1e-80
gi|24430141 fibrillin 1 precursor [Homo sapiens] 287 5e-77
gi|46249414 latent transforming growth factor beta binding prote... 283 5e-76
gi|46249412 latent transforming growth factor beta binding prote... 283 5e-76
gi|66346695 fibrillin 2 precursor [Homo sapiens] 283 9e-76
gi|110347437 latent transforming growth factor beta binding prot... 282 1e-75
gi|110347412 latent transforming growth factor beta binding prot... 282 1e-75
gi|110347431 latent transforming growth factor beta binding prot... 282 1e-75
gi|118572606 hemicentin 1 [Homo sapiens] 278 3e-74
gi|4557733 latent transforming growth factor beta binding protei... 277 4e-74
gi|19743803 fibulin 5 precursor [Homo sapiens] 262 2e-69
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 243 8e-64
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 243 8e-64
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 243 8e-64
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 231 4e-60
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 231 4e-60
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 202 2e-51
gi|194328809 latent transforming growth factor beta binding prot... 202 2e-51
gi|18497288 latent transforming growth factor beta binding prote... 200 8e-51
gi|134244285 Notch homolog 3 [Homo sapiens] 185 3e-46
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 2648 bits (6863), Expect = 0.0
Identities = 1231/1231 (100%), Positives = 1231/1231 (100%)
Query: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ
Sbjct: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
Query: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN
Sbjct: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
Query: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN
Sbjct: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
Query: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS
Sbjct: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
Query: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG
Sbjct: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
Query: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP
Sbjct: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
Query: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED
Sbjct: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
Query: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC
Sbjct: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
Query: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN
Sbjct: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
Query: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL
Sbjct: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA
Sbjct: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
Query: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQ 720
LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQ
Sbjct: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQ 720
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG
Sbjct: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
Query: 781 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 840
EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR
Sbjct: 781 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 840
Query: 841 QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG
Sbjct: 841 QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC
Sbjct: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL 1020
QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL
Sbjct: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL 1020
Query: 1021 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT
Sbjct: 1021 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
Query: 1081 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF 1140
HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF
Sbjct: 1081 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF 1140
Query: 1141 QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD 1200
QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD
Sbjct: 1141 QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD 1200
Query: 1201 FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1231
FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL
Sbjct: 1201 FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1231
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 2055 bits (5324), Expect = 0.0
Identities = 998/1238 (80%), Positives = 1037/1238 (83%), Gaps = 61/1238 (4%)
Query: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ
Sbjct: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
Query: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN
Sbjct: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
Query: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN
Sbjct: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
Query: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS
Sbjct: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
Query: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG
Sbjct: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
Query: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP
Sbjct: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
Query: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED
Sbjct: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
Query: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC
Sbjct: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
Query: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN
Sbjct: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
Query: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL
Sbjct: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA
Sbjct: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
Query: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQ 720
LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCED
Sbjct: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
+EC+ H CSR + CVNTLGSF+C + C GY L +C D++EC HTC G
Sbjct: 721 NECVTDLHTCSRGEHCVNTLGSFHCYK-ALTCEPGYALK-DGECEDVDECAMGTHTCQPG 778
Query: 781 EHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 839
C NT GSF+C C G+ +G C D++EC + C+PGF C NT GS+ CQ
Sbjct: 779 FLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQR 838
Query: 840 RQR-CMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
C G+ +G CVD+NEC + C G C N GSY C C G+
Sbjct: 839 NPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD-----CKAGFQRD 893
Query: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPG 957
G C+DVNEC R + C N GSYRC C +GF A G+ C DVNEC A
Sbjct: 894 AFGRGCIDVNECWASPGRLCQ-HTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--- 949
Query: 958 RLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR---CSQECANIYGSYQCYC 1014
+ C C N GSY+C C G+ LA DG C D++EC C+ C N+ GSYQC C
Sbjct: 950 QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1009
Query: 1015 -RQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
QGY + +G +C D+DECA G +C +
Sbjct: 1010 PEQGYTMTANGRSCKDVDECALGT------------------------------HNCSEA 1039
Query: 1074 DECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARI 1133
+ C HNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARI
Sbjct: 1040 ETC-------------HNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARI 1086
Query: 1134 THYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQR 1193
THYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQR
Sbjct: 1087 THYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQR 1146
Query: 1194 AVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1231
AVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL
Sbjct: 1147 AVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1184
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 620 bits (1600), Expect = e-177
Identities = 279/546 (51%), Positives = 358/546 (65%), Gaps = 50/546 (9%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVS-------------------------- 213
Query: 743 FYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C D+NEC+T H+C GE C+NT+GSF C + +C GY
Sbjct: 214 ---------------------CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGY 252
Query: 803 AL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+QD GNC+DINEC
Sbjct: 253 ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINEC 312
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 921
S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+EC CG+G
Sbjct: 313 LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHR 372
Query: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTLGSY CSC+ GF L
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRL 432
Query: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTCTDIDECA-QGAGI 1039
+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC DIDECA G
Sbjct: 433 SVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGH 492
Query: 1040 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS ETC NIQG FRCL
Sbjct: 493 ICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Query: 1100 RFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAF 1159
FECP NY + + T+CER CH+ EC P RIT+Y L+F T + PA +FR+GP+ A
Sbjct: 553 AFECPENYRRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAV 612
Query: 1160 TGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1219
GD++ L I GNEEG+F TR+++ ++GVV L + V EPRD L V+M L R G+V++F+
Sbjct: 613 PGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV 672
Query: 1220 AKMHIF 1225
AK+ IF
Sbjct: 673 AKLFIF 678
Score = 248 bits (633), Expect = 3e-65
Identities = 195/617 (31%), Positives = 262/617 (42%), Gaps = 123/617 (19%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL 758
C G+ A G +C D +ECL + C C+NT GS+ C + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 759 NAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECEDVDE 814
N +CVD++EC C +G CVN+ GSF C C+ GY DG C DV+E
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC----ECKTGYYF-DGISRMCVDVNE 402
Query: 815 C-AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
C C G C+NT GS+ C C GF +G +C DINEC+ S PC
Sbjct: 403 CQRYPGRLC--GHKCENTLGSYLCS----CSVGFRLSVDGRSCEDINECS--SSPCSQ-- 452
Query: 873 SCINTVGSYTCQRNPLICARGYHASD-DGTKCVDVNEC--ETGVHRCGEGQVCHNLPGSY 929
C N GSY C C RGY SD DG C D++EC TG H C C N+PGS+
Sbjct: 453 ECANVYGSYQC-----YCRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCINIPGSF 505
Query: 930 RCDC-KAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRC---SCASGFLLAAD 984
+C C +G++ GR C D++EC TC N G +RC C + +A
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA- 564
Query: 985 GKRCEDVNECEAQRCSQ 1001
RCE + E + CS+
Sbjct: 565 ATRCERLPCHENRECSK 581
Score = 128 bits (322), Expect = 3e-29
Identities = 120/381 (31%), Positives = 154/381 (40%), Gaps = 72/381 (18%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDQDECL 724
N C + PC Q C+ V GS C C GY + DGV+CED DEC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 M--GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGE 781
+ G H CS R C+N GSF C + GY L + R C DI+ECVT +H CS E
Sbjct: 487 LPTGGHICSYR--CINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 782 HCVNTLGSFHCYKALTCEPGY 802
C N G F C A C Y
Sbjct: 541 TCFNIQGGFRCL-AFECPENY 560
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 514 bits (1323), Expect = e-145
Identities = 256/569 (44%), Positives = 332/569 (58%), Gaps = 69/569 (12%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVS-------------------------- 213
Query: 743 FYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C D+NEC+T H+C GE C+NT+GSF C + +C GY
Sbjct: 214 ---------------------CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGY 252
Query: 803 AL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+QD GNC+DINEC
Sbjct: 253 ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINEC 312
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 921
S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+EC CG+G
Sbjct: 313 LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHR 372
Query: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTLGSY CSC+ GF L
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRL 432
Query: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTCTDIDECA-QGAGI 1039
+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC DIDECA G
Sbjct: 433 SVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGH 492
Query: 1040 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS ETC NIQG FRCL
Sbjct: 493 ICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Query: 1100 RFECPPNY------VQVSKT---KCERTTCHDFLECQNSPAR-ITHYQLNFQT--GLLVP 1147
FECP NY +Q KT +C ++ + + C P I+H ++ T P
Sbjct: 553 AFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRP 612
Query: 1148 AHIF---RIGPAPAFTGDTIALNIIKGNEEGYFG--TRRLNAYT-GVVYLQRAVLEPRDF 1201
I I P + I +I +GN F R ++ T GVV R ++ P
Sbjct: 613 EEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA 672
Query: 1202 ALDVEMKLWRQGSVT-TFLAKMHIFFTTF 1229
L +EM G V+ + +HIF + +
Sbjct: 673 VLKLEMNYVVGGVVSHRNVVNVHIFVSEY 701
Score = 244 bits (624), Expect = 3e-64
Identities = 193/619 (31%), Positives = 261/619 (42%), Gaps = 125/619 (20%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL 758
C G+ A G +C D +ECL + C C+NT GS+ C + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 759 NAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECEDVDE 814
N +CVD++EC C +G CVN+ GSF C C+ GY DG C DV+E
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC----ECKTGYYF-DGISRMCVDVNE 402
Query: 815 C-AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
C C G C+NT GS+ C C GF +G +C DINEC+ S PC
Sbjct: 403 CQRYPGRLC--GHKCENTLGSYLCS----CSVGFRLSVDGRSCEDINECS--SSPCSQ-- 452
Query: 873 SCINTVGSYTCQRNPLICARGYHASD-DGTKCVDVNEC--ETGVHRCGEGQVCHNLPGSY 929
C N GSY C C RGY SD DG C D++EC TG H C C N+PGS+
Sbjct: 453 ECANVYGSYQC-----YCRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCINIPGSF 505
Query: 930 RCDC-KAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRC---SCASGFLLAAD 984
+C C +G++ GR C D++EC TC N G +RC C + +A
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAA 565
Query: 985 GKRCEDVNECEAQRCSQEC 1003
+ E + + RC + C
Sbjct: 566 TLQQE---KTDTVRCIKSC 581
Score = 128 bits (322), Expect = 3e-29
Identities = 120/381 (31%), Positives = 154/381 (40%), Gaps = 72/381 (18%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDQDECL 724
N C + PC Q C+ V GS C C GY + DGV+CED DEC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 M--GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGE 781
+ G H CS R C+N GSF C + GY L + R C DI+ECVT +H CS E
Sbjct: 487 LPTGGHICSYR--CINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 782 HCVNTLGSFHCYKALTCEPGY 802
C N G F C A C Y
Sbjct: 541 TCFNIQGGFRCL-AFECPENY 560
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 509 bits (1310), Expect = e-144
Identities = 224/435 (51%), Positives = 281/435 (64%), Gaps = 50/435 (11%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVS-------------------------- 213
Query: 743 FYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C D+NEC+T H+C GE C+NT+GSF C + +C GY
Sbjct: 214 ---------------------CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGY 252
Query: 803 AL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+QD GNC+DINEC
Sbjct: 253 ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINEC 312
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 921
S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+EC CG+G
Sbjct: 313 LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHR 372
Query: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTLGSY CSC+ GF L
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRL 432
Query: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTCTDIDECA-QGAGI 1039
+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC DIDECA G
Sbjct: 433 SVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGH 492
Query: 1040 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS ETC NIQG FRCL
Sbjct: 493 ICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Query: 1100 RFECPPNYVQVSKTK 1114
FECP NY + + T+
Sbjct: 553 AFECPENYRRSAATQ 567
Score = 243 bits (621), Expect = 6e-64
Identities = 187/586 (31%), Positives = 249/586 (42%), Gaps = 119/586 (20%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL 758
C G+ A G +C D +ECL + C C+NT GS+ C + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 759 NAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECEDVDE 814
N +CVD++EC C +G CVN+ GSF C C+ GY DG C DV+E
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC----ECKTGYYF-DGISRMCVDVNE 402
Query: 815 C-AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
C C G C+NT GS+ C C GF +G +C DINEC+ S PC
Sbjct: 403 CQRYPGRLC--GHKCENTLGSYLCS----CSVGFRLSVDGRSCEDINECS--SSPCSQ-- 452
Query: 873 SCINTVGSYTCQRNPLICARGYHASD-DGTKCVDVNEC--ETGVHRCGEGQVCHNLPGSY 929
C N GSY C C RGY SD DG C D++EC TG H C C N+PGS+
Sbjct: 453 ECANVYGSYQC-----YCRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCINIPGSF 505
Query: 930 RCDC-KAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRC 973
+C C +G++ GR C D++EC TC N G +RC
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 128 bits (322), Expect = 3e-29
Identities = 120/381 (31%), Positives = 154/381 (40%), Gaps = 72/381 (18%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDQDECL 724
N C + PC Q C+ V GS C C GY + DGV+CED DEC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 M--GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGE 781
+ G H CS R C+N GSF C + GY L + R C DI+ECVT +H CS E
Sbjct: 487 LPTGGHICSYR--CINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 782 HCVNTLGSFHCYKALTCEPGY 802
C N G F C A C Y
Sbjct: 541 TCFNIQGGFRCL-AFECPENY 560
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 508 bits (1309), Expect = e-143
Identities = 224/434 (51%), Positives = 280/434 (64%), Gaps = 50/434 (11%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVS-------------------------- 213
Query: 743 FYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C D+NEC+T H+C GE C+NT+GSF C + +C GY
Sbjct: 214 ---------------------CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGY 252
Query: 803 AL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+QD GNC+DINEC
Sbjct: 253 ELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINEC 312
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 921
S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+EC CG+G
Sbjct: 313 LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHR 372
Query: 922 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTLGSY CSC+ GF L
Sbjct: 373 CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRL 432
Query: 982 AADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTCTDIDECA-QGAGI 1039
+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC DIDECA G
Sbjct: 433 SVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGH 492
Query: 1040 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS ETC NIQG FRCL
Sbjct: 493 ICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Query: 1100 RFECPPNYVQVSKT 1113
FECP NY + + T
Sbjct: 553 AFECPENYRRSAAT 566
Score = 243 bits (621), Expect = 6e-64
Identities = 187/586 (31%), Positives = 249/586 (42%), Gaps = 119/586 (20%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL 758
C G+ A G +C D +ECL + C C+NT GS+ C + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 759 NAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECEDVDE 814
N +CVD++EC C +G CVN+ GSF C C+ GY DG C DV+E
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC----ECKTGYYF-DGISRMCVDVNE 402
Query: 815 C-AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
C C G C+NT GS+ C C GF +G +C DINEC+ S PC
Sbjct: 403 CQRYPGRLC--GHKCENTLGSYLCS----CSVGFRLSVDGRSCEDINECS--SSPCSQ-- 452
Query: 873 SCINTVGSYTCQRNPLICARGYHASD-DGTKCVDVNEC--ETGVHRCGEGQVCHNLPGSY 929
C N GSY C C RGY SD DG C D++EC TG H C C N+PGS+
Sbjct: 453 ECANVYGSYQC-----YCRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCINIPGSF 505
Query: 930 RCDC-KAGFQRDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRC 973
+C C +G++ GR C D++EC TC N G +RC
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 128 bits (322), Expect = 3e-29
Identities = 120/381 (31%), Positives = 154/381 (40%), Gaps = 72/381 (18%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDQDECL 724
N C + PC Q C+ V GS C C GY + DGV+CED DEC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 M--GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGE 781
+ G H CS R C+N GSF C + GY L + R C DI+ECVT +H CS E
Sbjct: 487 LPTGGHICSYR--CINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 782 HCVNTLGSFHCYKALTCEPGY 802
C N G F C A C Y
Sbjct: 541 TCFNIQGGFRCL-AFECPENY 560
>gi|190343004 EGF-containing fibulin-like extracellular matrix protein
2 [Homo sapiens]
Length = 443
Score = 300 bits (769), Expect = 4e-81
Identities = 154/390 (39%), Positives = 212/390 (54%), Gaps = 36/390 (9%)
Query: 843 CMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTC------------------ 883
C DG+ DP+ +C D+NEC ++ E C+ CIN G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 884 ----QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 939
++P C GY DD CVDV+EC +H C Q CHNLPGSY+C C G+++
Sbjct: 99 PVPPAQHPNPCPPGYEP-DDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 940 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE-AQR 998
G C+D++EC R CQH C N GS+RC C GF L + + C DVNEC+
Sbjct: 158 --IGPECVDIDECRY---RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP 212
Query: 999 CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPE 1058
C Q C N YG++ C C QGY+L DG +C+DIDEC+ + LC +RC+N PG + C CP
Sbjct: 213 CEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSS-YLCQYRCVNEPGRFSCHCP- 270
Query: 1059 QGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFE-CPPNYVQVSKTKCER 1117
QGY + A R C+D+DEC G H CSEA+TC N G +RC+ C Y+QVS+ +C
Sbjct: 271 QGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLC 329
Query: 1118 TTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYF 1177
+ C+ P+ I H + + VPA +F+I + G A I GN +G F
Sbjct: 330 PASNPL--CREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDF 387
Query: 1178 GTRRLNAYTGVVYLQRAVLEPRDFALDVEM 1207
R++N + ++ L R V PR++ LD+EM
Sbjct: 388 YIRQINNVSAMLVLARPVTGPREYVLDLEM 417
Score = 150 bits (378), Expect = 9e-36
Identities = 104/327 (31%), Positives = 134/327 (40%), Gaps = 57/327 (17%)
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCV----------------- 746
C GY D C D +ECL C C+N G + C+
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 747 -----NHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG 801
H C GY + CVD++EC LH C + C N GS+ C TC G
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC----TCPDG 154
Query: 802 YALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINE 860
Y EC D+DEC CQ C N GSF CQ C GF P +CVD+NE
Sbjct: 155 YRKIGPECVDIDECRY--RYCQ--HRCVNLPGSFRCQ----CEPGFQLGPNNRSCVDVNE 206
Query: 861 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 920
C + PC C N+ G++ C+ C +GY DG C D++EC + C
Sbjct: 207 C-DMGAPCEQ--RCFNSYGTFLCR-----CHQGYELHRDGFSCSDIDECSYSSYLC--QY 256
Query: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ-HTCENTLGSYRCSCASGF 979
C N PG + C C G+Q A R C D++EC + + + TC N G YRC
Sbjct: 257 RCVNEPGRFSCHCPQGYQLLA-TRLCQDIDECESGAHQCSEAQTCVNFHGGYRC------ 309
Query: 980 LLAADGKRC-EDVNECEAQRCSQECAN 1005
D RC E + RC +N
Sbjct: 310 ---VDTNRCVEPYIQVSENRCLCPASN 333
Score = 113 bits (282), Expect = 1e-24
Identities = 97/312 (31%), Positives = 127/312 (40%), Gaps = 60/312 (19%)
Query: 597 PNSLPGDDQDECLLLPGELC--QHLCINTVGSYHCACFPGFSLQD-DGRTCRPEGHPPQP 653
P+S D +ECL +P E C + CIN G Y C + D G P P Q
Sbjct: 47 PDSQHCRDVNECLTIP-EACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQH 105
Query: 654 EAPQEPALK----------SEFSQVASNTIP------LPLPQPNTCKDN----GP----- 688
P P + E +Q + P LP TC D GP
Sbjct: 106 PNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDI 165
Query: 689 -------CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLG 741
C+ C + GS C C PG+ + + SC D +EC MGA C +R C N+ G
Sbjct: 166 DECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQR--CFNSYG 222
Query: 742 SFYCVNHTVLCADGYILNAHR---KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTC 798
+F C C GY L HR C DI+EC + C CVN G F C+ C
Sbjct: 223 TFLC-----RCHQGYEL--HRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCH----C 269
Query: 799 EPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVD 857
GY L C+D+DEC G H C C N G + C RC++ ++Q E C+
Sbjct: 270 PQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCL- 328
Query: 858 INECTSLSEPCR 869
C + + CR
Sbjct: 329 ---CPASNPLCR 337
Score = 107 bits (267), Expect = 7e-23
Identities = 80/237 (33%), Positives = 104/237 (43%), Gaps = 52/237 (21%)
Query: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRC---------- 973
P SY +C G++ D + C DVNEC P C + C N G Y C
Sbjct: 33 PDSYT-ECTDGYEWDPDSQHCRDVNECLTIP-EACKGEMKCINHYGGYLCLPRSAAVIND 90
Query: 974 -----------------SCASGFLLAADGKRCEDVNECEAQ----RCSQECANIYGSYQC 1012
C G+ D C DV+EC R SQ+C N+ GSYQC
Sbjct: 91 LHGEGPPPPVPPAQHPNPCPPGY-EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC 149
Query: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
C GY+ + G C DIDEC C RC+N+PGS++C C E G+ + N RSC D
Sbjct: 150 TCPDGYR--KIGPECVDIDECRYR---YCQHRCVNLPGSFRCQC-EPGFQLGPNNRSCVD 203
Query: 1073 VDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNS 1129
V+EC +G C + C N G+F C C Y + + +C D EC S
Sbjct: 204 VNECDMGA-PCE--QRCFNSYGTFLC---RCHQGY----ELHRDGFSCSDIDECSYS 250
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 299 bits (765), Expect = 1e-80
Identities = 221/639 (34%), Positives = 282/639 (44%), Gaps = 122/639 (19%)
Query: 506 DNDSCGISL---YKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVP 562
D D CG++L Y+ CC +G G CE+ P+ P + S C
Sbjct: 922 DEDECGVTLPGKYRMDVCCCSIGA---VWGVECEACPD---PESLEFASLC--------- 966
Query: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCI 621
PR + A R+ LS + D +EC + PG LC H C
Sbjct: 967 -----------PRGLG---FASRDFLSGRPFYK--------DVNECKVFPG-LCTHGTCR 1003
Query: 622 NTVGSYHCACFPGFSLQDDGRTCR--------PE--------GHPPQPEAPQEPALKSEF 665
NTVGS+HCAC GF+L R C P+ P E P +S F
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSC 717
+ + C D C + C+ GS C C PG+ + A G +C
Sbjct: 1064 MLMKN------------CMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Query: 718 EDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHT 776
ED DEC + C Q CVN +G+F C H G+ R+ CVDINEC
Sbjct: 1112 EDIDECSLSDGLCPHGQ-CVNVIGAFQCSCHA-----GFQSTPDRQGCVDINECRVQNGG 1165
Query: 777 CSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQNTKGS 834
C HC+NT GS+ C +C GY+L DG C DVDEC C G C N G
Sbjct: 1166 CD--VHCINTEGSYRC----SCGQGYSLMPDGRACADVDECEENPRVCDQGH-CTNMPGG 1218
Query: 835 FYCQARQRCMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 893
C C DGF+ P+ CVD++EC C G C NT GS+ C C G
Sbjct: 1219 HRCL----CYDGFMATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVCH-----CQLG 1268
Query: 894 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECW 953
Y T C DV+ECE G H C C N+PGS+ C C G+ D F C D++EC
Sbjct: 1269 YMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGF--ECHDLDECV 1326
Query: 954 ASPGRLC-QHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGS 1009
+ R + C N GSYRC+C GF A DG CED +EC C +C N G
Sbjct: 1327 SQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQCLNAPGG 1384
Query: 1010 YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTF-RCLNVPGSYQCACPEQGYTMTANGR 1068
Y+C C G+ ED C D+DECAQG LC F C N+PG ++C C GY + G
Sbjct: 1385 YRCECEMGFDPTEDHRACQDVDECAQGN--LCAFGSCENLPGMFRCIC-NGGYELDRGGG 1441
Query: 1069 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
+C D++ECA NC C N GS+ C CP ++
Sbjct: 1442 NCTDINECA-DPVNCING-VCINTPGSYLC---SCPQDF 1475
Score = 277 bits (708), Expect = 5e-74
Identities = 224/723 (30%), Positives = 295/723 (40%), Gaps = 136/723 (18%)
Query: 448 AGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDN 507
+G+ + D +EC P T T C +C G A + + D
Sbjct: 979 SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHC-------ACAGGF--ALDAQERNCTDI 1029
Query: 508 DSCGISLYKQCCDCCGLGLRVRAEGQ-SCESNPNLGYPCNHVML-SCCEGEEPLIVPEVR 565
D C IS D CG G V G CE P GY +++ +C + +E P +
Sbjct: 1030 DECRISP-----DLCGQGTCVNTPGSFECECFP--GYESGFMLMKNCMDVDECARDPLLC 1082
Query: 566 RPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCINTV 624
R G E + GT E D DEC L G LC H C+N +
Sbjct: 1083 RGGTCTNTDGSYKCQCPPGHELTAKGTACE--------DIDECSLSDG-LCPHGQCVNVI 1133
Query: 625 GSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
G++ C+C GF D + C N C+
Sbjct: 1134 GAFQCSCHAGFQSTPDRQGC---------------------------------VDINECR 1160
Query: 685 -DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
NG C C GS CSC GY++M DG +C D DEC C + C N G
Sbjct: 1161 VQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGH-CTNMPG-- 1217
Query: 744 YCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
H LC DG++ R CVD++EC + H C G+ C NT GSF C+ C+ GY
Sbjct: 1218 ---GHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGD-CENTKGSFVCH----CQLGY 1269
Query: 803 ALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE 860
++ G C DVDEC +G H C C N GSF C RC+ G++ D C D++E
Sbjct: 1270 MVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC----RCLPGWVGD-GFECHDLDE 1324
Query: 861 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 920
C S C P C+N GSY C C +G+ + DG C D +EC V C GQ
Sbjct: 1325 CVSQEHRCSPRGDCLNVPGSYRC-----TCRQGF--AGDGFFCEDRDECAENVDLCDNGQ 1377
Query: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGF 979
C N PG YRC+C+ GF R C DV+EC + G LC +CEN G +RC C G+
Sbjct: 1378 -CLNAPGGYRCECEMGFDPTEDHRACQDVDEC--AQGNLCAFGSCENLPGMFRCICNGGY 1434
Query: 980 LLAADGKRCEDVNEC-EAQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDID------ 1031
L G C D+NEC + C + C N GSY C C Q ++L G C D
Sbjct: 1435 ELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFL 1494
Query: 1032 ----------ECAQ--GAGILCTFRCLNV---------------PGSYQCACP-EQGYTM 1063
C+ G G+ C ++ Y+ CP +G+
Sbjct: 1495 ETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQP 1554
Query: 1064 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDF 1123
+D+DEC C + C N GSF+C ECPP Y T+ C D
Sbjct: 1555 NRITVILEDIDECQELPGLCQGGD-CVNTFGSFQC---ECPPGYHLSEHTR----ICEDI 1606
Query: 1124 LEC 1126
EC
Sbjct: 1607 DEC 1609
Score = 263 bits (671), Expect = 1e-69
Identities = 230/769 (29%), Positives = 321/769 (41%), Gaps = 135/769 (17%)
Query: 447 AAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETC-GAE 505
A G + +D DEC + P + T C C+ G+ +G C
Sbjct: 564 APGGHYCMDIDEC-QTPGICVNGHCTNTEGSFRC-------QCLGGLAVGTDGRVCVDTH 615
Query: 506 DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY--PCN--------HVMLSCCEG 555
+C ++ K C G ++E C +NP+ G+ PC C G
Sbjct: 616 VRSTCYGAIEKGSCARPFPGTVTKSE--CCCANPDHGFGEPCQLCPAKDSAEFQALCSSG 673
Query: 556 ----EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLL 611
+ + E PE A + R +LG EA D DEC L
Sbjct: 674 LGITTDGRDINECALDPE-VCANGVCENLRGSYRCVCNLGYEAGASGK-DCTDVDECAL- 730
Query: 612 PGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVAS 670
LC + C N+ GSY C+C PGF D C+ E P + +A
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVD-----ECLSSPCVSGVCRNLAG 785
Query: 671 NTI------PLPLPQPNTCKDN--GPC-------------------KQVCSTVGGS--AI 701
+ P C D+ G C + C+T+G + +
Sbjct: 786 SYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSP 845
Query: 702 C-------SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCAD 754
C +C G+A M GV+C+D +EC C + CVNT GSF C C +
Sbjct: 846 CERCEIDPACARGFARMT-GVTCDDVNECESFPGVCPNGR-CVNTAGSFRCE-----CPE 898
Query: 755 GYILNAH-RKCVDI-----------NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEP-- 800
G +L+A R CVD+ +EC L R + C ++G+ + C
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPE 958
Query: 801 ------------GYALKDGEC-----EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 843
G+A +D +DV+EC + C G C+NT GSF+C C
Sbjct: 959 SLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHG-TCRNTVGSFHCA----C 1013
Query: 844 MDGFLQDP-EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTK 902
GF D E NC DI+EC + C G +C+NT GS+ C+ C GY + K
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLCGQG-TCVNTPGSFECE-----CFPGYESGFMLMK 1067
Query: 903 -CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 961
C+DV+EC C G C N GSY+C C G + A G C D++EC S G LC
Sbjct: 1068 NCMDVDECARDPLLC-RGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG-LCP 1125
Query: 962 H-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGY 1018
H C N +G+++CSC +GF D + C D+NEC Q C C N GSY+C C QGY
Sbjct: 1126 HGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGY 1185
Query: 1019 QLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECAL 1078
L DG C D+DEC + + C N+PG ++C C + G+ T + R+C DVDEC L
Sbjct: 1186 SLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD-GFMATPDMRTCVDVDECDL 1244
Query: 1079 GTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
H C + C N +GSF C C Y+ + T C D EC+
Sbjct: 1245 NPHICLHGD-CENTKGSFVC---HCQLGYM----VRKGATGCSDVDECE 1285
Score = 259 bits (663), Expect = 8e-69
Identities = 225/771 (29%), Positives = 294/771 (38%), Gaps = 160/771 (20%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVC------RTAQRHCCVSYLQEKSCMAGVLGAKEG 499
C G + C +I E T +C T + CV C A L G
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCV-------CPAEYLQVNGG 1642
Query: 500 ETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPL 559
C C ++ C L + C + N+G N
Sbjct: 1643 NNCMDMRKSVC----FRHYNGTCQNELAFNVTRKMCCCSYNIGQAWN------------- 1685
Query: 560 IVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHL 619
RP E P + G +A T+ L D DEC +P +
Sbjct: 1686 ------RPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPL---DIDECGEIPAICANGI 1736
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP---ALKSEFSQVASNTIPLP 676
CIN +GS+ C C GF+ C E+P + + S T
Sbjct: 1737 CINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYK 1796
Query: 677 LPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAH 728
L C C+++ C GS +C C G+ AD C D DEC
Sbjct: 1797 LSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDEC--DRQ 1854
Query: 729 DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLG 788
C C N +GS+ C LC G+++ + CVD +EC T + R HC+NT G
Sbjct: 1855 PCGNGT-CKNIIGSYNC-----LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 789 SFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG 846
SFHC C+ G+ L DG+ C D +EC TC PG CQN +GSF C C G
Sbjct: 1909 SFHCL----CQDGFELTADGKNCVDTNECLSLAGTCLPG-TCQNLEGSFRCI----CPPG 1959
Query: 847 FLQDPEGNCVDINEC----------TSLSEP------CRPGF-------SCINTVGSYT- 882
F Q +C+DI+EC T + P C PGF C +T S+
Sbjct: 1960 F-QVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF 2018
Query: 883 ----------------------CQRNP--------------------LICARGYHA---S 897
C + P +C G+ A
Sbjct: 2019 TRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP 2078
Query: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPG 957
DD + DVNEC C G VC N GS+RC+C G+ D G C+D +EC S G
Sbjct: 2079 DDSRE--DVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINCVDTDEC--SVG 2133
Query: 958 RLC-QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYC 1014
C Q TC N +G + C+CA GF CED++EC C+ C N GSY C C
Sbjct: 2134 HPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 1015 RQGYQLAEDGHTCTDIDECAQGAGILCTFR---CLNVPGSYQCACPEQGYTMTANGRSCK 1071
GY L EDG C D+DECA G C R C N+ G++ C CP + +G C
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQD-CHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 1072 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHD 1122
D +EC C C N GSFRC +C + Q S T T CHD
Sbjct: 2252 DDNECHAQPDLCVNGR-CVNTAGSFRC---DCDEGF-QPSPT---LTECHD 2294
Score = 254 bits (648), Expect = 5e-67
Identities = 207/612 (33%), Positives = 258/612 (42%), Gaps = 120/612 (19%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC------------------- 644
D DEC P C N+ GS+ C C PGF L D+G C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 645 ---------------RP-EGH-PPQPEAPQE-PALKSEFSQVASNTIPLP---LPQPNTC 683
RP EG P PQE A E +P P N C
Sbjct: 2029 PKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNEC 2088
Query: 684 KDN-GPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLG 741
+N G C VC GS C C GY++ G++C D DEC +G H C + C N +G
Sbjct: 2089 AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGT-CTNVIG 2146
Query: 742 SFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG 801
F C CADG+ C DI+EC + C+ C NT GS+ C TC G
Sbjct: 2147 GFECA-----CADGFEPGLMMTCEDIDECSLNPLLCAF--RCHNTEGSYLC----TCPAG 2195
Query: 802 YALKD--GECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CV 856
Y L++ C DVDECA G C G C+N G+F C C G P C
Sbjct: 2196 YTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACV----CPPGMRPLPGSGEGCT 2251
Query: 857 DINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVN--------- 907
D NEC + + C G C+NT GS+ C C G+ S T+C D+
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCD-----CDEGFQPSPTLTECHDIRQGPCFAEVL 2305
Query: 908 -----------------ECETGVHRCGEGQVCH--NLPGS--YRCDCKAGFQRDAFGRGC 946
EC G R G G C LPG+ YR C G A GR
Sbjct: 2306 QTMCRSLSSSSEAVTRAECCCGGGR-GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR-- 2362
Query: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQEC 1003
DV+EC LC H C N+LGS+RC C +G+ A C D++EC + C+ C
Sbjct: 2363 -DVDEC-RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLC 2420
Query: 1004 ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTM 1063
N GS+ C C +GY L EDG TC D+DEC C F C+N G++ C CP G+T
Sbjct: 2421 KNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHN-CQFLCVNTVGAFTCRCPP-GFTQ 2478
Query: 1064 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDF 1123
+ ++C D DEC+ C CHN GSFRC EC + VS C D
Sbjct: 2479 --HHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC---ECHQGFTLVSSGH----GCEDV 2529
Query: 1124 LECQNSPARITH 1135
EC + P R H
Sbjct: 2530 NEC-DGPHRCQH 2540
Score = 253 bits (647), Expect = 6e-67
Identities = 249/901 (27%), Positives = 337/901 (37%), Gaps = 197/901 (21%)
Query: 422 DPNSVHSIPRSSPEGSTKDL---IETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRH 478
D N S+ + G+ ++L C G Q + +D C++I E E N+C
Sbjct: 1929 DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQ--VQSDHCIDIDECSEEPNLCLFGT-- 1984
Query: 479 CCVSYLQEKSCMA--GVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCE 536
C + C+ G + + G C C R E C
Sbjct: 1985 -CTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF----------------TRFEAGKC- 2026
Query: 537 SNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRV--SEAEMAGREALSLGTEA 594
++ N CC +RP E P + E A +E G A
Sbjct: 2027 ---SVPKAFNTTKTRCCCS---------KRPGEGWGDPCELCPQEGSAAFQELCPFGHGA 2074
Query: 595 ELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPE-----GH 649
+D +EC PG +C+NT GS+ C C G+SL G C GH
Sbjct: 2075 VPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134
Query: 650 PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-------CSTVGGSAIC 702
P + F ++ L TC+D C C GS +C
Sbjct: 2135 PCGQGTCTN--VIGGFECACADGFEPGLMM--TCEDIDECSLNPLLCAFRCHNTEGSYLC 2190
Query: 703 SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQF-CVNTLGSFYCV--------------- 746
+C GY + DG C D DEC G DC R C N +G+F CV
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 747 -------NHTVLCADGYILNAH-----------------RKCVDI--------------- 767
LC +G +N +C DI
Sbjct: 2251 TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCR 2310
Query: 768 -----NECVTDLHTCSRG--------EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE 814
+E VT C G E C L Y+ L C G E DVDE
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGWGPRCELC--PLPGTSAYRKL-CPHGSGYT-AEGRDVDE 2366
Query: 815 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFS 873
C M H C G C N+ GSF C C G+ D C+D++EC+ + +PC F
Sbjct: 2367 CRMLAHLCAHGE-CINSLGSFRCH----CQAGYTPDATATTCLDMDECSQVPKPCT--FL 2419
Query: 874 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 933
C NT GS+ C C RGY +DG C D++EC + H C +C N G++ C C
Sbjct: 2420 CKNTKGSFLCS-----CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRC 2472
Query: 934 KAGFQRDAFGRGCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVN 992
GF + + C D +EC A PG H C NT GS+RC C GF L + G CEDVN
Sbjct: 2473 PPGFTQHH--QACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVN 2530
Query: 993 ECEA-QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1051
EC+ RC C N G Y+C C QG+ C D +ECA + C N G
Sbjct: 2531 ECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 1052 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1111
++C CP G+ C++VDECA CS + C N G F C CP Y +
Sbjct: 2591 FRCVCPS-GFDFDQALGGCQEVDECAGRRGPCSYS--CANTPGGFLC---GCPQGYFRAG 2644
Query: 1112 KTKC-----------------ERTTCHDFLECQ-------NSPARITH--YQLNFQTG-- 1143
+ C E + EC+ + P R H +Q+N T
Sbjct: 2645 QGHCVSGLGFSPGPQDTPDKEELLSSEACYECKINGLSPRDRPRRSAHRDHQVNLATLDS 2704
Query: 1144 ---LLVPAHIFRIGPA-------PAFTG--DTIALNIIKGNEEGYFGTRRLNAYTGVVYL 1191
L + ++ +G A PA G I I++GNE+G+F R++ GV L
Sbjct: 2705 EALLTLGLNLSHLGRAERILELRPALEGLEGRIRYVIVRGNEQGFF---RMHHLRGVSSL 2761
Query: 1192 Q 1192
Q
Sbjct: 2762 Q 2762
Score = 249 bits (635), Expect = 1e-65
Identities = 225/787 (28%), Positives = 308/787 (39%), Gaps = 130/787 (16%)
Query: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVL 494
+T+ + C AG + + D C++ E T +C C++ SC+ G L
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNG---VCLNEDGSFSCLCKPGFL 562
Query: 495 GAKEGETCGAEDNDSC---GISLYKQC--------CDCCGLGLRVRAEGQSCESNPNLGY 543
A G C D D C GI + C C C G GL V +G+ C
Sbjct: 563 LAPGGHYC--MDIDECQTPGICVNGHCTNTEGSFRCQCLG-GLAVGTDGRVCVDTHVRST 619
Query: 544 PCNHVMLSCCEGEEPLIVPEVR----RPPEPAAAPRRVSEA-EMAGREALSLGTEAELPN 598
+ C P V + P P ++ A + A +AL + L
Sbjct: 620 CYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALC---SSGLGI 676
Query: 599 SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE 658
+ G D +EC L P +C N GSY C C G+ G+ C E
Sbjct: 677 TTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD---------VDE 727
Query: 659 PALKS-----EFSQVASNTIPLPLP-------QPNTCKD-----NGPC-KQVCSTVGGSA 700
AL S + Q + + P CKD + PC VC + GS
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSY 787
Query: 701 ICSCFPGYAIMADGVSCED-----------QDECLMGAHDCSRRQFCVNTLGSFY---CV 746
C C PG + G C D + C + S R C TLG+ + C
Sbjct: 788 TCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCE 847
Query: 747 NHTV--LCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL 804
+ CA G+ C D+NEC + C G CVNT GSF C C G L
Sbjct: 848 RCEIDPACARGFARMTGVTCDDVNECESFPGVCPNG-RCVNTAGSFRC----ECPEGLML 902
Query: 805 KDGE--CEDV-----------DECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP 851
C DV DEC + +C + G+ + + C D +
Sbjct: 903 DASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEF 962
Query: 852 EGNC------------------VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 893
C D+NEC C G +C NTVGS+ C CA G
Sbjct: 963 ASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHG-TCRNTVGSFHC-----ACAGG 1016
Query: 894 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD-AFGRGCIDVNEC 952
+ C D++EC CG+G C N PGS+ C+C G++ + C+DV+EC
Sbjct: 1017 FALDAQERNCTDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNCMDVDEC 1075
Query: 953 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ--RCSQ-ECANIYGS 1009
P TC NT GSY+C C G L A G CED++EC C +C N+ G+
Sbjct: 1076 ARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGA 1135
Query: 1010 YQCYCRQGYQLAEDGHTCTDIDEC-AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR 1068
+QC C G+Q D C DI+EC Q G C C+N GSY+C+C QGY++ +GR
Sbjct: 1136 FQCSCHAGFQSTPDRQGCVDINECRVQNGG--CDVHCINTEGSYRCSC-GQGYSLMPDGR 1192
Query: 1069 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQN 1128
+C DVDEC C + C N+ G RCL C ++ + TC D EC
Sbjct: 1193 ACADVDECEENPRVCDQGH-CTNMPGGHRCL---CYDGFMATP----DMRTCVDVDECDL 1244
Query: 1129 SPARITH 1135
+P H
Sbjct: 1245 NPHICLH 1251
Score = 244 bits (624), Expect = 3e-64
Identities = 196/634 (30%), Positives = 255/634 (40%), Gaps = 115/634 (18%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +EC + G C CINT GSY C+C G+SL DGR C E + P +
Sbjct: 1155 DINECRVQNGG-CDVHCINTEGSYRCSCGQGYSLMPDGRACADVD-----ECEENPRV-- 1206
Query: 664 EFSQVASNTIP-----------LPLPQPNTCKDNGPCKQV--------CSTVGGSAICSC 704
Q +P + P TC D C C GS +C C
Sbjct: 1207 -CDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHC 1265
Query: 705 FPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKC 764
GY + C D DEC +G H+C C+N GSF C C G++ + +C
Sbjct: 1266 QLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-----RCLPGWVGDGF-EC 1319
Query: 765 VDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQP 824
D++ECV+ H CS C+N GS+ C TC G+A CED DECA C
Sbjct: 1320 HDLDECVSQEHRCSPRGDCLNVPGSYRC----TCRQGFAGDGFFCEDRDECAENVDLCDN 1375
Query: 825 GFLCQNTKGSFYCQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSY 881
G C N G + C+ C GF DP + C D++EC C G SC N G +
Sbjct: 1376 G-QCLNAPGGYRCE----CEMGF--DPTEDHRACQDVDECAQ-GNLCAFG-SCENLPGMF 1426
Query: 882 TCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 941
C IC GY G C D+NEC V+ C G VC N PGSY C C F+ +
Sbjct: 1427 RC-----ICNGGYELDRGGGNCTDINECADPVN-CING-VCINTPGSYLCSCPQDFELNP 1479
Query: 942 FGRGCIDVN-----------------------------ECWASPGRLCQHTCE-----NT 967
G GC+D C S GR + CE NT
Sbjct: 1480 SGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANT 1539
Query: 968 LGSYRCSC--ASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLAE 1022
YR C GF ED++EC+ C +C N +GS+QC C GY L+E
Sbjct: 1540 T-EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 1023 DGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE--CALGT 1080
C DIDEC+ +GI C N G+Y C CP + Y G +C D+ + C
Sbjct: 1599 HTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAE-YLQVNGGNNCMDMRKSVCFRHY 1657
Query: 1081 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER-----TTCHDFLECQNSPARITH 1135
+ + E N+ C C N Q CE + + L +P +T
Sbjct: 1658 NGTCQNELAFNVTRKMCC----CSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLT- 1712
Query: 1136 YQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNII 1169
+ TG P I G PA + I +N I
Sbjct: 1713 ---DIHTG--KPLDIDECGEIPAICANGICINQI 1741
Score = 244 bits (623), Expect = 4e-64
Identities = 193/642 (30%), Positives = 260/642 (40%), Gaps = 139/642 (21%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA- 660
+D+DEC +LC + C+N G Y C C GF +D R C+ Q +
Sbjct: 1361 EDRDECAENV-DLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSC 1419
Query: 661 --LKSEFSQVASNTIPLP-----LPQPNTCKDNGPC-KQVCSTVGGSAICSCFPGYAIMA 712
L F + + L N C D C VC GS +CSC + +
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 713 DGVSCED--QDECLMGAHD-------CS-------RRQFCVNTLGSFY-----------C 745
GV C D C + HD CS R C +LG +
Sbjct: 1480 SGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANT 1539
Query: 746 VNHTVLCADGYILNAHRKCV---DINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
+ LC G +R V DI+EC +L +G CVNT GSF C C PGY
Sbjct: 1540 TEYRTLCPGGEGFQPNRITVILEDIDEC-QELPGLCQGGDCVNTFGSFQC----ECPPGY 1594
Query: 803 ALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDIN 859
L + CED+DEC+ + C PG C NT G++ C C +LQ G NC+D+
Sbjct: 1595 HLSEHTRICEDIDECSTHSGICGPG-TCYNTLGNYTCV----CPAEYLQVNGGNNCMDMR 1649
Query: 860 E-------------------------------------CTSLSEPCRPGFS--CINTVGS 880
+ C + P P + C N
Sbjct: 1650 KSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPG 1709
Query: 881 Y-------------TCQRNPLICARGYHASDDGT----------------KCVDVNECET 911
+ C P ICA G + G+ C DV+EC +
Sbjct: 1710 FLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGS 1769
Query: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGS 970
C + C N+PGSYRC C G++ G C+ NEC P +C H C +T GS
Sbjct: 1770 RESPCQQNADCINIPGSYRCKCTRGYKLSP-GGACVGRNECREIP-NVCSHGDCMDTEGS 1827
Query: 971 YRCSCASGFLLAADGKRCEDVNECEAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTD 1029
Y C C GF +AD C D++EC+ Q C C NI GSY C C G+ + +G C D
Sbjct: 1828 YMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVD 1886
Query: 1030 IDECAQGAGILCTF-RCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAET 1088
DEC G +C F CLN GS+ C C + G+ +TA+G++C D +EC C T
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLC-QDGFELTADGKNCVDTNECLSLAGTCLPG-T 1944
Query: 1089 CHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
C N++GSFRC+ CPP + + + C D EC P
Sbjct: 1945 CQNLEGSFRCI---CPPGF------QVQSDHCIDIDECSEEP 1977
Score = 224 bits (572), Expect = 3e-58
Identities = 183/597 (30%), Positives = 250/597 (41%), Gaps = 127/597 (21%)
Query: 596 LPNSLPG--DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------ 646
+PN G D DEC +PG LCQ C+N VGS+HC C G L D C
Sbjct: 237 IPNIHTGACQDVDECQAVPG-LCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGAC 295
Query: 647 -------------EGH----------------PPQPEAPQEPALKSEFSQVASNTIPLPL 677
GH P PE P +EF Q+ + +PL
Sbjct: 296 FSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCP-PRGSNEFQQLCAQRLPLLP 354
Query: 678 PQPNTCKDN------------GPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLM 725
P GP + I S PG + + + D C
Sbjct: 355 GHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRH 414
Query: 726 GAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVN 785
+ C + C+ T S+ C C GY + +C+D++EC + C G+ CVN
Sbjct: 415 FTNLCLNGR-CLPTPSSYRCE-----CNVGYTQDVRGECIDVDECTSS--PCHHGD-CVN 465
Query: 786 TLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 843
G++HC C PG+ C DVDEC + C G C NT+GSF C C
Sbjct: 466 IPGTYHC----RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQCV----C 516
Query: 844 MDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTK 902
GF P+G NCVD NEC + S C G C+N GS++C +C G+ + G
Sbjct: 517 NAGFELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSC-----LCKPGFLLAPGGHY 569
Query: 903 CVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE---------- 951
C+D++EC+T G+ C G C N GS+RC C G GR C+D +
Sbjct: 570 CMDIDECQTPGI--CVNGH-CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEK 626
Query: 952 ----------------CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDV 991
C A+P G CQ ++ C+SG + DG+ D+
Sbjct: 627 GSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR---DI 683
Query: 992 NEC--EAQRCSQE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNV 1048
NEC + + C+ C N+ GSY+C C GY+ G CTD+DECA + + C N
Sbjct: 684 NECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNS 743
Query: 1049 PGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1105
PGSY C+CP G+ + CKDVDEC + C C N+ GS+ C +C P
Sbjct: 744 PGSYSCSCP-PGFHFWQDTEICKDVDECL--SSPCVSG-VCRNLAGSYTC---KCGP 793
Score = 200 bits (509), Expect = 6e-51
Identities = 177/552 (32%), Positives = 232/552 (42%), Gaps = 125/552 (22%)
Query: 614 ELCQH---LCIN-----TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
++C+H LC+N T SY C C G++ QD ++ E
Sbjct: 410 DICRHFTNLCLNGRCLPTPSSYRCECNVGYT-QD---------------------VRGEC 447
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
V T + PC C + G+ C C+PG+ +C D DEC+
Sbjct: 448 IDVDECT-------------SSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECI 494
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHC 783
+ C + CVNT GSF CV C G+ L+ K CVD NEC T C G C
Sbjct: 495 VSGGLCHLGR-CVNTEGSFQCV-----CNAGFELSPDGKNCVDHNECATST-MCVNGV-C 546
Query: 784 VNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
+N GSF C C+PG+ L G C D+DEC C G C NT+GSF CQ
Sbjct: 547 LNEDGSFSC----LCKPGFLLAPGGHYCMDIDEC-QTPGICVNGH-CTNTEGSFRCQ--- 597
Query: 842 RCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYT----CQRNP--------- 887
C+ G +G CVD + ++ G G+ T C NP
Sbjct: 598 -CLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQ 656
Query: 888 -----------LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 936
+C+ G + DG D+NEC C G VC NL GSYRC C G
Sbjct: 657 LCPAKDSAEFQALCSSGLGITTDGR---DINECALDPEVCANG-VCENLRGSYRCVCNLG 712
Query: 937 FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE 995
++ A G+ C DV+EC A LC + C+N+ GSY CSC GF D + C+DV+EC
Sbjct: 713 YEAGASGKDCTDVDEC-ALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECL 771
Query: 996 AQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTD---------IDEC-----AQGAGIL 1040
+ C S C N+ GSY C C G +L G C D I E QGA L
Sbjct: 772 SSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGAS-L 830
Query: 1041 CTFRCLNVPGSYQCACPE--------QGYTMTANGRSCKDVDECALGTHNCSEAETCHNI 1092
+ C + ++ C +G+ G +C DV+EC C C N
Sbjct: 831 RSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNECESFPGVCPNGR-CVNT 888
Query: 1093 QGSFRCLRFECP 1104
GSFRC ECP
Sbjct: 889 AGSFRC---ECP 897
Score = 192 bits (488), Expect = 2e-48
Identities = 206/787 (26%), Positives = 275/787 (34%), Gaps = 202/787 (25%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQ--EKSCMAGVLGAKEGETCG 503
C G + C +I E D +C Q CV+ + + SC AG + + C
Sbjct: 1098 CPPGHELTAKGTACEDIDECSLSDGLCPHGQ---CVNVIGAFQCSCHAGFQSTPDRQGC- 1153
Query: 504 AEDNDSCGISLYKQCCDC------------CGLGLRVRAEGQSCESNPNLGYPCNHVMLS 551
D + C + CD CG G + +G++C +
Sbjct: 1154 -VDINECRVQ--NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD------------VD 1198
Query: 552 CCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLL 611
CE E P + + P G L P+ D DEC L
Sbjct: 1199 ECE-ENPRVCDQGHCTNMPG------------GHRCLCYDGFMATPDMRTCVDVDECDLN 1245
Query: 612 PGELCQHL-CINTVGSYHCACFPGFSLQ------DDGRTCRPEGHPPQPEAPQEPALKSE 664
P +C H C NT GS+ C C G+ ++ D C GH
Sbjct: 1246 P-HICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGH--------------- 1289
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
N C + GS C C PG+ + DG C D DEC+
Sbjct: 1290 ---------------------NCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDECV 1326
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCV 784
H CS R C+N GS+ C DG+ C D +EC ++ C G+ C+
Sbjct: 1327 SQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFF------CEDRDECAENVDLCDNGQ-CL 1379
Query: 785 NTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
N G + C CE G+ + C+DVDECA G + C G C+N G F C
Sbjct: 1380 NAPGGYRC----ECEMGFDPTEDHRACQDVDECAQG-NLCAFG-SCENLPGMFRC----I 1429
Query: 843 CMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 901
C G+ L GNC DINEC C G CINT GSY C C + + + G
Sbjct: 1430 CNGGYELDRGGGNCTDINECAD-PVNCINGV-CINTPGSYLCS-----CPQDFELNPSGV 1482
Query: 902 KCVD--VNECETGVHRCGE--------------------------GQVCHNLP----GSY 929
CVD C H G+ G C P Y
Sbjct: 1483 GCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEY 1542
Query: 930 RCDCKA--GFQRDAFGRGCIDVNECWASPGRLCQ-HTCENTLGSYRCSCASGFLLAADGK 986
R C GFQ + D++EC PG LCQ C NT GS++C C G+ L+ +
Sbjct: 1543 RTLCPGGEGFQPNRITVILEDIDECQELPG-LCQGGDCVNTFGSFQCECPPGYHLSEHTR 1601
Query: 987 RCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDE----------- 1032
CED++EC C C N G+Y C C Y G+ C D+ +
Sbjct: 1602 ICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTC 1661
Query: 1033 --------------CAQGAGILCTFRCLNVP----GSYQCACPEQ--GYTMTANGRSCKD 1072
C+ G C P YQ C Q G+ + D
Sbjct: 1662 QNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLD 1721
Query: 1073 VDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY---------VQVSKTKCERTTCHDF 1123
+DEC C+ C N GSFRC ECP + V + + C
Sbjct: 1722 IDECGEIPAICANG-ICINQIGSFRC---ECPAGFNYNSILLACEDVDECGSRESPCQQN 1777
Query: 1124 LECQNSP 1130
+C N P
Sbjct: 1778 ADCINIP 1784
Score = 155 bits (391), Expect = 3e-37
Identities = 140/465 (30%), Positives = 187/465 (40%), Gaps = 74/465 (15%)
Query: 689 CKQVCSTVG---GSAICSCFPGYAIMADGVSCEDQ---DECL--MGAHDCSR-------- 732
C + C G G C+C G+ G CE C +G C
Sbjct: 151 CDRGCHNGGRCIGPNRCACVYGFM----GPQCERDYRTGPCFGQVGPEGCQHQLTGLVCT 206
Query: 733 RQFCVNTLGSFY------CVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVN 785
+ C T+G + C C G+I N H C D++EC C G CVN
Sbjct: 207 KALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVN 265
Query: 786 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY-----CQAR 840
+GSFHC C G+ L D D A + G C Y C R
Sbjct: 266 MVGSFHC----RCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDR 321
Query: 841 QRCMDG----FLQDPEGNCVDINECTSLSEPCRPG----FSCINTVGSY-------TCQR 885
RC L P G+ + + + P PG F + GS +
Sbjct: 322 GRCWAAGPVPELCPPRGS-NEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARL 380
Query: 886 NPL------ICARGYHASDDGTKCVD--VNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 937
NP I + G S+ GT ++ ++ C + C G+ C P SYRC+C G+
Sbjct: 381 NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR-CLPTPSSYRCECNVGY 439
Query: 938 QRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-- 994
+D G CIDV+EC +SP C H C N G+Y C C GF + C DV+EC
Sbjct: 440 TQDVRGE-CIDVDECTSSP---CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIV 495
Query: 995 EAQRCS-QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQ 1053
C C N GS+QC C G++L+ DG C D +ECA + CLN GS+
Sbjct: 496 SGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATST-MCVNGVCLNEDGSFS 554
Query: 1054 CACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
C C + G+ + G C D+DEC T C N +GSFRC
Sbjct: 555 CLC-KPGFLLAPGGHYCMDIDECQ--TPGICVNGHCTNTEGSFRC 596
Score = 153 bits (386), Expect = 1e-36
Identities = 147/487 (30%), Positives = 196/487 (40%), Gaps = 83/487 (17%)
Query: 693 CSTVGGS-----AICSCFP-----GYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGS 742
C+TVG + +C P G+ +C+D DEC C CVN +GS
Sbjct: 211 CATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGS 269
Query: 743 FYCVNHTVLCADGYILN-AHRKCVDINE--CVTDLHTCSRGEHCVNTLGSFHCYKALTCE 799
F+C C G+ L+ + C D C + L G C L + + C+
Sbjct: 270 FHC-----RCPVGHRLSDSSAACEDYRAGACFSVLF----GGRCAGDLAGHYTRRQCCCD 320
Query: 800 PGYALKDGECEDV----------DECAM------GTHTCQPGFLCQNTKGSFYCQARQRC 843
G G ++ CA G PG L + G R
Sbjct: 321 RGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARL 380
Query: 844 MD------GFLQDPEGNC--------VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
G GN I+ C + C G C+ T SY C+
Sbjct: 381 NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNG-RCLPTPSSYRCE----- 434
Query: 890 CARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV 949
C GY D +C+DV+EC + G+ C N+PG+Y C C GFQ + C+DV
Sbjct: 435 CNVGY-TQDVRGECIDVDECTSSPCHHGD---CVNIPGTYHCRCYPGFQATPTRQACVDV 490
Query: 950 NECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIY 1007
+EC S G C NT GS++C C +GF L+ DGK C D NEC + C N
Sbjct: 491 DECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNED 550
Query: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1067
GS+ C C+ G+ LA GH C DIDEC Q GI C N GS++C C G + +G
Sbjct: 551 GSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGICVNGHCTNTEGSFRCQC-LGGLAVGTDG 608
Query: 1068 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTK-CERTTCHDFLE- 1125
R C D TH S TC+ C R P V+K++ C H F E
Sbjct: 609 RVCVD-------THVRS---TCYGAIEKGSCAR----PFPGTVTKSECCCANPDHGFGEP 654
Query: 1126 CQNSPAR 1132
CQ PA+
Sbjct: 655 CQLCPAK 661
Score = 59.3 bits (142), Expect = 2e-08
Identities = 79/291 (27%), Positives = 106/291 (36%), Gaps = 84/291 (28%)
Query: 785 NTLGS-FHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ-- 841
N GS FH Y C PG+ G +C + +C+ G +C
Sbjct: 58 NVCGSRFHAY----CCPGWRTFPGR----SQCVVP--------ICRRACGEGFCSQPNLC 101
Query: 842 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL-------ICARGY 894
C DG L G ++ + S C G +C S CQ+ IC RG
Sbjct: 102 TCADGTLAPSCG----VSRGSGCSVSCMNGGTCRGA--SCLCQKGYTGTVCGQPICDRGC 155
Query: 895 HASDDGTKCVDVNECETGV----------HRCGE--GQV----C-HNLPG---------- 927
H +G +C+ N C +R G GQV C H L G
Sbjct: 156 H---NGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCA 212
Query: 928 ------SYRCD--------CKAGFQRDAFGRGCIDVNECWASPGRLCQ-HTCENTLGSYR 972
C+ C+ GF + C DV+EC A PG LCQ +C N +GS+
Sbjct: 213 TVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPG-LCQGGSCVNMVGSFH 271
Query: 973 CSCASGFLLAADGKRCED--VNECEA----QRCSQECANIYGSYQCYCRQG 1017
C C G L+ CED C + RC+ + A Y QC C +G
Sbjct: 272 CRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 59.3 bits (142), Expect = 2e-08
Identities = 65/244 (26%), Positives = 91/244 (37%), Gaps = 52/244 (21%)
Query: 840 RQRCMDGFLQDPEGNCVDINECTSLSEPCRP------GFSC-INTVGSYTCQRNPLICAR 892
R+ C +GF P N CT P G C ++ + TC+ +C +
Sbjct: 87 RRACGEGFCSQP-------NLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQK 139
Query: 893 GYHASDDGTKCVDVNECETGVHRCGEGQVCHN---LPGSYRCDCKAGFQRDAFGRGCIDV 949
GY GT C G C G CHN G RC C GF R
Sbjct: 140 GY----TGTVC--------GQPICDRG--CHNGGRCIGPNRCACVYGFMGPQCERD-YRT 184
Query: 950 NECWASPG-RLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYG 1008
C+ G CQH + + CA+ + A G CE C AQ
Sbjct: 185 GPCFGQVGPEGCQHQLTGLVCTKALCCAT--VGRAWGLPCE---LCPAQPHP-------- 231
Query: 1009 SYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR 1068
CR+G+ C D+DEC G+ C+N+ GS+ C CP G+ ++ +
Sbjct: 232 -----CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCP-VGHRLSDSSA 285
Query: 1069 SCKD 1072
+C+D
Sbjct: 286 ACED 289
Score = 47.4 bits (111), Expect = 9e-05
Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 36/237 (15%)
Query: 912 GVHRCGEGQVCHNLPG----SYRCDCKAGFQRDAFGRG-CIDVNECWASPGRL------- 959
G + CG + PG R C R A G G C N C + G L
Sbjct: 56 GPNVCGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVS 115
Query: 960 ----CQHTCEN--TLGSYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQ 1011
C +C N T C C G+ G+ D RC CA +YG
Sbjct: 116 RGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMG 175
Query: 1012 CYCRQGYQLAEDGHTCTDIDECAQGAGILCT--FRCLNVPGSYQCACP---------EQG 1060
C + Y+ Q G++CT C V ++ C +G
Sbjct: 176 PQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRG 235
Query: 1061 YTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKCE 1116
+ + +C+DVDEC C + +C N+ GSF C CP + + S CE
Sbjct: 236 FIPNIHTGACQDVDECQAVPGLC-QGGSCVNMVGSFHC---RCPVGHRLSDSSAACE 288
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 287 bits (734), Expect = 5e-77
Identities = 203/626 (32%), Positives = 273/626 (43%), Gaps = 145/626 (23%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGR--------TC--RPEGHP-- 650
+D DEC + PG LC+NT GS+ C C G +L GR TC R E
Sbjct: 909 EDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECT 968
Query: 651 ----------------------------PQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
P P+ L A+ I P
Sbjct: 969 LPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKP---F 1025
Query: 683 CKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQ 734
KD CK + C GS C C G+A+ ++ +C D DEC + C R Q
Sbjct: 1026 FKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
Query: 735 FCVNTLGSFYCVNHTVLCADGYILN--AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHC 792
CVNT G F C C +GY + C+DI+EC D C RG C NT GS+ C
Sbjct: 1086 -CVNTPGDFECK-----CDEGYESGFMMMKNCMDIDECQRDPLLC-RGGVCHNTEGSYRC 1138
Query: 793 YKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD 850
C PG+ L C D++EC + H C P C N G + C C G+
Sbjct: 1139 ----ECPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHST 1189
Query: 851 PEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC 909
P+ CVDI+EC+ ++ C C N+ GSY C C G+ D C D++EC
Sbjct: 1190 PDRLFCVDIDECSIMNGGCET--FCTNSEGSYECS-----CQPGFALMPDQRSCTDIDEC 1242
Query: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE---- 965
E + C GQ C N+PG YRC C GF + C+DVNEC +P TCE
Sbjct: 1243 EDNPNICDGGQ-CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKG 1301
Query: 966 ---------------------------------------NTLGSYRCSCASGFLLAADGK 986
NT GS++CSC+ G++ DG
Sbjct: 1302 SFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGI 1359
Query: 987 RCEDVNECE--AQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCT 1042
+C D++EC CSQ +C N GSY+C C++GY DG TCTD+DEC++ +
Sbjct: 1360 KCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGN 1417
Query: 1043 FRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFE 1102
+CLN PG Y+C C + G+ +A+G++C+D+DEC+L N TCHN+ G FRC E
Sbjct: 1418 GQCLNAPGGYRCEC-DMGFVPSADGKACEDIDECSL--PNICVFGTCHNLPGLFRC---E 1471
Query: 1103 CPPNYVQVSKTKCERT--TCHDFLEC 1126
C Y + +R+ C D EC
Sbjct: 1472 CEIGY------ELDRSGGNCTDVNEC 1491
Score = 273 bits (698), Expect = 7e-73
Identities = 235/771 (30%), Positives = 318/771 (41%), Gaps = 172/771 (22%)
Query: 455 DNDECLEIP---ESGTEDNVCRTAQRHCCVSY-LQEKSCMAGVLGAKEGETCGAEDNDSC 510
D DEC E+P + G N + Q C Y L E + + E ET G +C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD--DVNECETPGICGPGTC 1663
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEV------ 564
++ C C ++V + +L Y + C+GE + +
Sbjct: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY 1723
Query: 565 ------RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH 618
+P E P A + G + G ++ LP D DEC +PG
Sbjct: 1724 NIGRAWNKPCEQCPIPSTDEFATLCGSQRP--GFVIDIYTGLPVDI-DECREIPGVCENG 1780
Query: 619 LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP 678
+CIN VGS+ C C GF D C
Sbjct: 1781 VCINMVGSFRCECPVGFFYNDKLLVCE--------------------------------- 1807
Query: 679 QPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFC 736
+ C++ C++ C GS C C PGY + G C D++EC + CS Q C
Sbjct: 1808 DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQ-C 1865
Query: 737 VNTLGSFYCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKA 795
++T+GSFYC+ HT G+ N + C+DINEC D C G C NT+GSF+C
Sbjct: 1866 IDTVGSFYCLCHT-----GFKTNDDQTMCLDINECERD--ACGNGT-CRNTIGSFNC--- 1914
Query: 796 LTCEPGYALK-DGECEDVDECAMGT-HTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 853
C G+ L + +C DVDECA G + C+ G C NT GSF CQ C +G+ P+G
Sbjct: 1915 -RCNHGFILSHNNDCIDVDECASGNGNLCRNG-QCINTVGSFQCQ----CNEGYEVAPDG 1968
Query: 854 -NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETG 912
CVDINEC C PG +C N GSY C IC GY ++ KC D++EC
Sbjct: 1969 RTCVDINECLLEPRKCAPG-TCQNLDGSYRC-----ICPPGYSLQNE--KCEDIDECVEE 2020
Query: 913 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV----------------------- 949
C G C N GS++C C GF + GR C D+
Sbjct: 2021 PEICALG-TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHS 2079
Query: 950 -NEC--------WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRC 999
EC W P LC + C SG ++ D D++EC E C
Sbjct: 2080 KQECCCALKGEGWGDPCELCPTEPDEAFRQI-CPYGSGIIVGPDDS-AVDMDECKEPDVC 2137
Query: 1000 SQ-ECANIYGSYQCYCRQGYQLA--------------------------------EDGH- 1025
+C N GSY+C C GY LA E+G
Sbjct: 2138 KHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE 2197
Query: 1026 -----TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
TC DI+ECAQ +LC FRC+N GSY+C CP GY + + R CKD DEC G
Sbjct: 2198 PGPMMTCEDINECAQNP-LLCAFRCVNTYGSYECKCP-VGYVLREDRRMCKDEDECEEGK 2255
Query: 1081 HNCSEAE-TCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
H+C+E + C N+ G++ C+ C P Y + + + C D ECQ P
Sbjct: 2256 HDCTEKQMECKNLIGTYMCI---CGPGY----QRRPDGEGCVDENECQTKP 2299
Score = 263 bits (672), Expect = 8e-70
Identities = 241/800 (30%), Positives = 325/800 (40%), Gaps = 124/800 (15%)
Query: 433 SPEGSTKDLIETC------CAAGQQWAIDND-ECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
+P+G T I C CA G +D C+ P ++ C CV +
Sbjct: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDE--CVE--E 2020
Query: 486 EKSCMAGVLGAKEGE-TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYP 544
+ C G EG C + S S ++C D + EG C S +
Sbjct: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSS-GRRCQDLRMSYCYAKFEGGKCSSPKSR--- 2076
Query: 545 CNHVMLSCC---EGE---EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPN 598
NH CC +GE +P + P EP + A R+ G+ +
Sbjct: 2077 -NHSKQECCCALKGEGWGDPCELC----PTEP----------DEAFRQICPYGSGIIVGP 2121
Query: 599 SLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQ 657
D DEC ++C+H CINT GSY C C G+ L G C
Sbjct: 2122 DDSAVDMDECK--EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCG 2177
Query: 658 EPALKSEFSQVASNTIPLPLPQPN-TCKDNGPCKQV-------CSTVGGSAICSCFPGYA 709
K+ P P TC+D C Q C GS C C GY
Sbjct: 2178 NGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYV 2237
Query: 710 IMADGVSCEDQDECLMGAHDCSRRQF-CVNTLGSFYCVNHTVLCADGYILNAHRK-CVDI 767
+ D C+D+DEC G HDC+ +Q C N +G++ C+ C GY + CVD
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGCVDE 2292
Query: 768 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE------CAMGTHT 821
NEC T C G C+NT GS+ C C G+ + E +D + +
Sbjct: 2293 NECQTKPGICENGR-CLNTRGSYTC----ECNDGFTASPNQDECLDNREGYCFTEVLQNM 2347
Query: 822 CQPGFLCQN--TKGSFYCQARQ----RCMDGFLQD--------PEG-----NCVDINECT 862
CQ G +N TK C + C Q P G N DI+EC
Sbjct: 2348 CQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECK 2407
Query: 863 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVC 922
+ + CR G C+N GSY C IC GY GT CVD+NEC C +C
Sbjct: 2408 VIHDVCRNG-ECVNDRGSYHC-----ICKTGYTPDITGTSCVDLNECNQAPKPCNF--IC 2459
Query: 923 HNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLA 982
N GSY+C C G+ GR C D++EC A+ CQ C NT+G + C C GF
Sbjct: 2460 KNTEGSYQCSCPKGYILQEDGRSCKDLDEC-ATKQHNCQFLCVNTIGGFTCKCPPGF--T 2516
Query: 983 ADGKRCEDVNEC--EAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 1038
C D NEC + C + C N GS+ C C++G+ L + G +C D+DEC
Sbjct: 2517 QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE--GN 2574
Query: 1039 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
C C N+ G Y+C+CP QGY C D +EC L H C A +CHN GS++C
Sbjct: 2575 HRCQHGCQNIIGGYRCSCP-QGYLQHYQWNQCVDENEC-LSAHICGGA-SCHNTLGSYKC 2631
Query: 1099 LRFECPP--NYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL--VPAHIFRIG 1154
+ CP Y Q S C D EC ++ A ++ N + G L P FRIG
Sbjct: 2632 M---CPAGFQYEQFS------GGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIG 2682
Query: 1155 PAPAFTGDTIALNIIKGNEE 1174
+G + + +GN E
Sbjct: 2683 QGHCVSG----MGMGRGNPE 2698
Score = 247 bits (631), Expect = 4e-65
Identities = 177/568 (31%), Positives = 240/568 (42%), Gaps = 132/568 (23%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
+D++EC +P +C H CI+TVGS++C C GF DD C
Sbjct: 1848 NDRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL---------------- 1890
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
N C+ + C GS C C G+ I++ C D D
Sbjct: 1891 -----------------DINECERDACGNGTCRNTIGSFNCRCNHGF-ILSHNNDCIDVD 1932
Query: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGY-ILNAHRKCVDINECVTDLHTCSRG 780
EC G + R C+NT+GSF C C +GY + R CVDINEC+ + C+ G
Sbjct: 1933 ECASGNGNLCRNGQCINTVGSFQC-----QCNEGYEVAPDGRTCVDINECLLEPRKCAPG 1987
Query: 781 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYC--- 837
C N GS+ C C PGY+L++ +CED+DEC C G C NT+GSF C
Sbjct: 1988 T-CQNLDGSYRC----ICPPGYSLQNEKCEDIDECVEEPEICALG-TCSNTEGSFKCLCP 2041
Query: 838 ------QARQRCMD------------GFLQDPEGNCVDINEC------TSLSEPCR---- 869
+ +RC D G P+ EC +PC
Sbjct: 2042 EGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT 2101
Query: 870 ---PGFSCINTVGSYTCQ------------RNPLICARGYHASDDGT------------- 901
F I GS + P +C G + DG+
Sbjct: 2102 EPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAG 2161
Query: 902 -KCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
+CVD +EC G + CG G C N+ G + C C+ GF+ C D+NEC +P LC
Sbjct: 2162 NECVDTDECSVG-NPCGNG-TCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNP-LLC 2217
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ---ECANIYGSYQCYCR 1015
C NT GSY C C G++L D + C+D +ECE + C++ EC N+ G+Y C C
Sbjct: 2218 AFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICG 2277
Query: 1016 QGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1075
GYQ DG C D +EC GI RCLN GSY C C G+T + N C D E
Sbjct: 2278 PGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCEC-NDGFTASPNQDECLDNRE 2336
Query: 1076 -----------CALGTHN---CSEAETC 1089
C +G+ N +++E C
Sbjct: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECC 2364
Score = 247 bits (630), Expect = 6e-65
Identities = 213/762 (27%), Positives = 294/762 (38%), Gaps = 153/762 (20%)
Query: 445 CCAAGQQWAIDNDECLEIPESGTED--------------------------NVCRTAQRH 478
CC+ G W +EC E P T + N C+
Sbjct: 981 CCSVGAAWG--TEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSL 1038
Query: 479 C----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQS 534
C C + + C A + E D D C IS D CG G V G
Sbjct: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISP-----DLCGRGQCVNTPGDF 1093
Query: 535 CESNPNLGYPCNHVMLSCCEG-----EEPLIVP-----------EVRRPPEPAAAPR--- 575
E + GY +M+ C +PL+ PP +P
Sbjct: 1094 -ECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISA 1152
Query: 576 --RVSEAEMA------GREALSLGTEA--------ELPNSLPGDDQDECLLLPGELCQHL 619
++E E++ GR +G P+ L D DEC ++ G C+
Sbjct: 1153 CIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG-CETF 1211
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP----EGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C N+ GSY C+C PGF+L D R+C E +P + Q + E+ + + +
Sbjct: 1212 CTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF-M 1270
Query: 676 PLPQPNTCKDNGPC--------KQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGA 727
TC D C C GS IC C GY+ C D +EC +GA
Sbjct: 1271 ASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGA 1330
Query: 728 HDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTL 787
H+C + C NT GSF C C+ G+I + KC D++EC H CS+ C NT+
Sbjct: 1331 HNCGKHAVCTNTAGSFKC-----SCSPGWIGDG-IKCTDLDECSNGTHMCSQHADCKNTM 1384
Query: 788 GSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 847
GS+ C C+ GY C D+DEC+ + C G C N G + C+ C GF
Sbjct: 1385 GSYRC----LCKEGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPGGYRCE----CDMGF 1435
Query: 848 LQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV 906
+ +G C DI+EC SL C G +C N G + C+ C GY G C DV
Sbjct: 1436 VPSADGKACEDIDEC-SLPNICVFG-TCHNLPGLFRCE-----CEIGYELDRSGGNCTDV 1488
Query: 907 NECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV--NECWAS---PGRLCQ 961
NEC C G C N PGSY CDC F+ + GC+D C+ G
Sbjct: 1489 NEC-LDPTTCISGN-CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGD 1546
Query: 962 HTCENTLG----SYRCSCASGFLLAADGKRC---------------------------ED 990
C N +G C C+ G + C ED
Sbjct: 1547 TACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILED 1606
Query: 991 VNECE--AQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLN 1047
++EC+ C +C N +GS+QC C GY L ED C D++EC + GI C N
Sbjct: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYN 1665
Query: 1048 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETC 1089
G+Y C CP Y G +C D+ + ++ +TC
Sbjct: 1666 TVGNYTCICPPD-YMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 229 bits (583), Expect = 2e-59
Identities = 191/629 (30%), Positives = 264/629 (41%), Gaps = 124/629 (19%)
Query: 591 GTEAELPNSLPG--DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE 647
G E PN + +D DEC LPG LCQ CINT GS+ C C G+ L +D R C
Sbjct: 1591 GGEGFRPNPITVILEDIDECQELPG-LCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
Query: 648 GHPPQPEAPQEPALKSEFSQVASNTIPLP-----LPQPNTCKD----------------- 685
+ E P + ++ V + T P + N C D
Sbjct: 1650 N---ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Query: 686 -----------------------NGPCKQ--VCSTVGGSAIC-SCFPGYAIMADGVSCED 719
N PC+Q + ST + +C S PG+ I D
Sbjct: 1707 DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVD 1766
Query: 720 QDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCS 778
DEC C C+N +GSF C C G+ N C DI+EC C
Sbjct: 1767 IDECREIPGVCENG-VCINMVGSFRCE-----CPVGFFYNDKLLVCEDIDECQNG-PVCQ 1819
Query: 779 RGEHCVNTLGSFHCYKALTCEPGYALKD-GECEDVDECAMGTHTCQPGFLCQNTKGSFYC 837
R C+NT GS+ C C+PGY G+C D +EC + C G C +T GSFYC
Sbjct: 1820 RNAECINTAGSYRC----DCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYC 1874
Query: 838 QARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA 896
C GF D + C+DINEC + C G +C NT+GS+ C+ C G+
Sbjct: 1875 L----CHTGFKTNDDQTMCLDINECER--DACGNG-TCRNTIGSFNCR-----CNHGFIL 1922
Query: 897 SDDGTKCVDVNECETGV-HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWAS 955
S + C+DV+EC +G + C GQ C N GS++C C G++ GR C+D+NEC
Sbjct: 1923 SHNND-CIDVDECASGNGNLCRNGQ-CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLE 1980
Query: 956 PGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCS-QECANIYGSYQC 1012
P + TC+N GSYRC C G+ L ++CED++EC E + C+ C+N GS++C
Sbjct: 1981 PRKCAPGTCQNLDGSYRCICPPGYSL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKC 2038
Query: 1013 YCRQGYQLAEDGHTCTDI------------------------DEC-----AQGAGILCTF 1043
C +G+ L+ G C D+ EC +G G C
Sbjct: 2039 LCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL 2098
Query: 1044 RCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFEC 1103
+++ CP + S D+DEC C + C N GS+RC EC
Sbjct: 2099 CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQ-CINTDGSYRC---EC 2153
Query: 1104 PPNYVQVSKTKCERTTCHDFLECQNSPAR 1132
P Y+ + C C N +
Sbjct: 2154 PFGYILAGNECVDTDECSVGNPCGNGTCK 2182
Score = 201 bits (512), Expect = 3e-51
Identities = 221/776 (28%), Positives = 290/776 (37%), Gaps = 137/776 (17%)
Query: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
AW P P +P +P+ D + +IP G+ T E C A
Sbjct: 216 AWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
Query: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETC------ 502
G + + +C +I E T +C + VS K C G + +G C
Sbjct: 276 GHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCK-CPPGFYTSPDGTRCIDVRPG 334
Query: 503 ---GAEDNDSCG------ISLYKQCCD---CCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
A N C I+ + CCD C G+ V E + + C+ M+
Sbjct: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
Query: 551 SCCEGEEP----------LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
E P L VP P PR E RE P L
Sbjct: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREP---------PRVL 445
Query: 601 PGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
P + D C L+ LCQ+ CI T GS C C GF L G + P A E
Sbjct: 446 PVNVTDYCQLVR-YLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE- 503
Query: 660 ALKSEFSQVASNTIPLPLPQPNT-CKDNGPCKQV--------CSTVGGSAICSCFPGYAI 710
+ ++ S T C+D C Q C GS C C G+ +
Sbjct: 504 CINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHV 563
Query: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINE 769
DG +CED DEC + C+N GSF C+ C G+ L + R C DINE
Sbjct: 564 TRDGKNCEDMDEC--SIRNMCLNGMCINEDGSFKCI-----CKPGFQLASDGRYCKDINE 616
Query: 770 CVTDLHTCSRGEHCVNTLGSFHC------------------YKALTCEPGYALKDGEC-- 809
C T C G CVNT GS+ C + TC GY K G+C
Sbjct: 617 CETP-GICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGY--KRGQCIK 672
Query: 810 -----EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL 864
EC + G CQ + + C G G+ DINEC
Sbjct: 673 PLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS--DINECALD 730
Query: 865 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 924
+ C P C N G+Y C IC GY G CVD+NEC C GQ C N
Sbjct: 731 PDIC-PNGICENLRGTYKC-----ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRN 783
Query: 925 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL--- 981
PGS+ C C GF + C D++EC +SP C+N+ GS+ C C+S L
Sbjct: 784 TPGSFVCTCPKGFIYKPDLKTCEDIDECESSP--CINGVCKNSPGSFICECSSESTLDPT 841
Query: 982 ---------------AADGKRCEDVNECEAQRCSQECANI---YGS------YQCYCRQG 1017
DG RCE +N A SQ C+++ +GS C +G
Sbjct: 842 KTICIETIKGTCWQTVIDG-RCE-ININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
Query: 1018 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
Y + G C DIDEC G+ C+N GS++C CP G T+ A GR C D+
Sbjct: 900 YSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP-SGMTLDATGRICLDI 953
Score = 200 bits (509), Expect = 6e-51
Identities = 145/436 (33%), Positives = 202/436 (46%), Gaps = 76/436 (17%)
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
D C + + C + C+ T GS C C G+ L+ +C+D++EC + + C+ G
Sbjct: 451 DYCQLVRYLCQNGR-CIPTPGSCRCE-----CNKGFQLDLRGECIDVDEC--EKNPCAGG 502
Query: 781 EHCVNTLGSFHCYKALTCEPGY--ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
E C+N GS+ C C GY L EC D+DEC C G C NT GSF+C
Sbjct: 503 E-CINNQGSYTCQ----CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCV 556
Query: 839 ARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
C GF +G NC D++EC S+ C G CIN GS+ C IC G+ +
Sbjct: 557 ----CNAGFHVTRDGKNCEDMDEC-SIRNMCLNGM-CINEDGSFKC-----ICKPGFQLA 605
Query: 898 DDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE----- 951
DG C D+NECET G+ C G+ C N GSYRC+C G GR C+D +
Sbjct: 606 SDGRYCKDINECETPGI--CMNGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCY 662
Query: 952 ---------------------CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGK 986
C AS G CQ Y+ C+SG + + G
Sbjct: 663 GGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS 722
Query: 987 RCEDVNEC--EAQRCSQE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTF 1043
D+NEC + C C N+ G+Y+C C GY++ G C DI+EC + +
Sbjct: 723 ---DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG 779
Query: 1044 RCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFEC 1103
+C N PGS+ C CP +G+ + ++C+D+DEC + C C N GSF C EC
Sbjct: 780 QCRNTPGSFVCTCP-KGFIYKPDLKTCEDIDECE--SSPCING-VCKNSPGSFIC---EC 832
Query: 1104 -PPNYVQVSKTKCERT 1118
+ + +KT C T
Sbjct: 833 SSESTLDPTKTICIET 848
Score = 183 bits (464), Expect = 1e-45
Identities = 166/624 (26%), Positives = 232/624 (37%), Gaps = 129/624 (20%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP-----------EGHPP 651
D DECL G +C + CINT GS+HC C GF + DG+ C G
Sbjct: 530 DIDECLQ-NGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCI 588
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYAI 710
+ + K F + + N C+ G C C GS C CFPG A+
Sbjct: 589 NEDGSFKCICKPGFQLASDGRYCKDI---NECETPGICMNGRCVNTDGSYRCECFPGLAV 645
Query: 711 MADGVSCED---QDECLMGAH--DCSRRQFCVNTLGSFYCVN------------------ 747
DG C D + C G C + F T C +
Sbjct: 646 GLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSA 705
Query: 748 -HTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD 806
+ LC+ G + + DINEC D C G C N G++ C C GY +
Sbjct: 706 EYQALCSSGPGMTSAGS--DINECALDPDICPNGI-CENLRGTYKCI----CNSGYEVDS 758
Query: 807 G--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE-GNCVDINECTS 863
C D++EC + + C G C+NT GSF C C GF+ P+ C DI+EC S
Sbjct: 759 TGKNCVDINECVLNSLLCDNG-QCRNTPGSFVCT----CPKGFIYKPDLKTCEDIDECES 813
Query: 864 LSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV-----------NECETG 912
PC G C N+ GS+ C+ C+ T C++ CE
Sbjct: 814 --SPCINGV-CKNSPGSFICE-----CSSESTLDPTKTICIETIKGTCWQTVIDGRCEIN 865
Query: 913 VHRCG-EGQVCHNLPGSYRCDCKAGFQRDAFGRG--------CIDVNECWASPGRLCQHT 963
++ + Q C +L ++ C G+G C D++EC PG
Sbjct: 866 INGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL 925
Query: 964 CENTLGSYRCSCASGFLLAADGKRCEDVN------ECEAQRCSQECANIYGSYQCYCRQG 1017
C NT GS++C C SG L A G+ C D+ E + C+ A + C C G
Sbjct: 926 CVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVG 985
Query: 1018 YQL-AEDGHTC------------------------------TDIDECAQGAGILCTFRCL 1046
E+ C DI+EC + +C
Sbjct: 986 AAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCR 1045
Query: 1047 NVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1106
N GS++C C + G+ + + R+C D+DEC + C + C N G F C +C
Sbjct: 1046 NTIGSFKCRC-DSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPGDFEC---KCDEG 1100
Query: 1107 YVQVSKTKCERTTCHDFLECQNSP 1130
Y C D ECQ P
Sbjct: 1101 Y---ESGFMMMKNCMDIDECQRDP 1121
Score = 122 bits (305), Expect = 3e-27
Identities = 70/171 (40%), Positives = 90/171 (52%), Gaps = 13/171 (7%)
Query: 959 LCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ-ECANIYGSYQCYCRQ 1016
LCQ+ C T GS RC C GF L G+ C DV+ECE C+ EC N GSY C CR
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRA 517
Query: 1017 GYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1076
GYQ C DIDEC Q I RC+N GS+ C C G+ +T +G++C+D+DEC
Sbjct: 518 GYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC-NAGFHVTRDGKNCEDMDEC 576
Query: 1077 ALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
++ N C N GSF+C+ C P + S + C D EC+
Sbjct: 577 SI--RNMCLNGMCINEDGSFKCI---CKPGFQLAS----DGRYCKDINECE 618
Score = 97.4 bits (241), Expect = 7e-20
Identities = 91/332 (27%), Positives = 125/332 (37%), Gaps = 53/332 (15%)
Query: 704 CFPGYAIMADGVSCED---QDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNA 760
C PG+ + G C + C G CSR C G C I +
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHSC--GDGFCSRPNMCTCPSGQI-----APSCGSRSIQHC 119
Query: 761 HRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTH 820
+ +C++ C D C +G +G+ HC + + CE G L G C + CA
Sbjct: 120 NIRCMNGGSCSDDHCLCQKGY-----IGT-HCGQPV-CESG-CLNGGRCVAPNRCA---- 167
Query: 821 TCQPGFL---CQN---TKGSFYCQARQRC---MDGFLQDPEGNCVDINECTSLSEPCRPG 871
C GF C+ T F + Q C + G + C + + PC
Sbjct: 168 -CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGR--AWGHPCE-- 222
Query: 872 FSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC 931
C P C RG+ + C DV+EC+ C +G C N GS+ C
Sbjct: 223 ----------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFEC 271
Query: 932 DCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDV 991
C AG + + + C D++EC PG C NT+ SY C C GF + DG RC DV
Sbjct: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
Query: 992 NE--CEAQ----RCSQECANIYGSYQCYCRQG 1017
C RCS + QC C G
Sbjct: 332 RPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 89.0 bits (219), Expect = 3e-17
Identities = 86/268 (32%), Positives = 102/268 (38%), Gaps = 56/268 (20%)
Query: 840 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 899
R C DGF P N CT S P SC GS + Q + C G SDD
Sbjct: 86 RHSCGDGFCSRP-------NMCTCPSGQIAP--SC----GSRSIQHCNIRCMNGGSCSDD 132
Query: 900 ---------GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF-----QRDAFGRG 945
GT C CE+G C G C RC C GF +RD
Sbjct: 133 HCLCQKGYIGTHCGQP-VCESG---CLNGGRC---VAPNRCACTYGFTGPQCERDYRTGP 185
Query: 946 CIDVNE-----------------CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC 988
C V C A+ GR H CE C GF+ C
Sbjct: 186 CFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGAC 244
Query: 989 EDVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 1045
+DV+EC+A C C N GS++C C G++L E C DIDEC+ GI C
Sbjct: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
Query: 1046 LNVPGSYQCACPEQGYTMTANGRSCKDV 1073
N SY C CP YT + +G C DV
Sbjct: 305 TNTVSSYFCKCPPGFYT-SPDGTRCIDV 331
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 283 bits (725), Expect = 5e-76
Identities = 211/628 (33%), Positives = 294/628 (46%), Gaps = 85/628 (13%)
Query: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 695 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 750
Query: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 751 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 810
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 811 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 860
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDQ 720
S SQV + P + + N C N C + C C+ GY C D
Sbjct: 861 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 917
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSR 779
DEC H CS+ + C NT GSF C+ C G++ + C+D++EC+ C
Sbjct: 918 DECTQVQHLCSQGR-CENTEGSFLCI-----CPAGFMASEEGTNCIDVDECLRP-DVCGE 970
Query: 780 GEHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
G HCVNT+G+F C C+ GY + + G CED+DEC + TC P C N+ GS+ C
Sbjct: 971 G-HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDEC-LNPSTC-PDEQCVNSPGSYQCV 1024
Query: 839 ARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASD 898
C +GF + G C+D++EC C G C N GSY C C +GY +
Sbjct: 1025 P---CTEGF-RGWNGQCLDVDECLE-PNVCANG-DCSNLEGSYMCS-----CHKGYTRTP 1073
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 958
D C D++EC+ G + C GQ C N GS+RC C G+Q A C D++EC
Sbjct: 1074 DHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC--QHRH 1129
Query: 959 LCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYC 1014
LC H C NT GS++C C G+ + G CED+NEC + C + +C N GSY C C
Sbjct: 1130 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTC 1189
Query: 1015 RQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
G+QL +D TC DI+EC CLN GS+ C C +QG++++A+GR+C+D+D
Sbjct: 1190 PDGFQL-DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDID 1247
Query: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFE 1102
EC T C C N GSFRCL ++
Sbjct: 1248 ECVNNT-VCDSHGFCDNTAGSFRCLCYQ 1274
Score = 222 bits (565), Expect = 2e-57
Identities = 185/588 (31%), Positives = 238/588 (40%), Gaps = 110/588 (18%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCA-CFPGFSLQDDGR-----------TCRPEGHPP 651
D DECL P + C+NTVG++ C C G+ + GR TC E
Sbjct: 958 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVN 1016
Query: 652 QPEAPQEPALKSEFSQVASNTIPLP-LPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAI 710
P + Q F + + +PN C + CS + GS +CSC GY
Sbjct: 1017 SPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-----CSNLEGSYMCSCHKGYTR 1071
Query: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINE 769
D C D DEC G + C Q C NT GSF C C GY L+A + +C DI+E
Sbjct: 1072 TPDHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCT-----CGQGYQLSAAKDQCEDIDE 1124
Query: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFL 827
C H C+ G+ C NT GSF C C+ GY CED++EC CQ G
Sbjct: 1125 C-QHRHLCAHGQ-CRNTEGSFQC----VCDQGYRASGLGDHCEDINECLEDKSVCQRGD- 1177
Query: 828 CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 887
C NT GS+ C C DGF D C DINEC C P C+NT GS+ C
Sbjct: 1178 CINTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGL-CGPQGECLNTEGSFHC---- 1228
Query: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 947
+C +G+ S DG C D++EC C C N GS+RC C GFQ G+GC+
Sbjct: 1229 -VCQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 1286
Query: 948 DVNECWASPGRLCQHTCENTLGSYRCSCA-----------------SGFLLAADGKRCED 990
DVNEC G + CEN GS+ C CA S L + E+
Sbjct: 1287 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1346
Query: 991 VNEC-----EAQRCSQECANIYGSYQCYCRQGYQLAED---------------------- 1023
EC +A C A +C C G ++
Sbjct: 1347 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1406
Query: 1024 -------------GHTCTDIDECAQ-GAGILCTFRCLNVPGSYQCACPEQGYTMTANGRS 1069
G D DEC G I CLN Y+C C +QG
Sbjct: 1407 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYC-KQGTYYDPVKLQ 1465
Query: 1070 CKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER 1117
C D+DEC +C + + C N +GS+ C F P + S+ +C R
Sbjct: 1466 CFDMDECQ-DPSSCIDGQ-CVNTEGSYNC--FCTHPMVLDASEKRCIR 1509
Score = 154 bits (388), Expect = 7e-37
Identities = 234/988 (23%), Positives = 323/988 (32%), Gaps = 309/988 (31%)
Query: 377 PRDPVKPSPHNILSTSL--------PDAAWIPPTREVPR-----------KPQVLP---- 413
P P K P L+ S P+ A PP +E+P +PQ+ P
Sbjct: 772 PPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGIST 831
Query: 414 -HSH-------VEEDTDPNSVHSIPRSSPEGSTKDLIET-------------CCAAG--- 449
H H +E+ + P V P +S +++ + T C AG
Sbjct: 832 IHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCI 891
Query: 450 -------------------QQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCM 490
Q+ +D DEC ++ ++ T C+ C
Sbjct: 892 NLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCI-------CP 944
Query: 491 AGVLGAKEGETCGAEDN----DSCG-------ISLYKQCCDCCGLGLRVRAEGQSCESNP 539
AG + ++EG C D D CG + ++ C+ C G R+ G+ CE
Sbjct: 945 AGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFR--CEYCDSGYRMTQRGR-CEDID 1001
Query: 540 NLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNS 599
P S C E+ V P P G+
Sbjct: 1002 ECLNP------STCPDEQC-----VNSPGSYQCVPCTEGFRGWNGQCL------------ 1038
Query: 600 LPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
D DECL P C N GSY C+C G++ D + CR Q
Sbjct: 1039 ----DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG 1093
Query: 660 ALKS---EFSQVASNTIPLPLPQPNTCKDNGPCKQ-------VCSTVGGSAICSCFPGYA 709
K+ F L + + C+D C+ C GS C C GY
Sbjct: 1094 QCKNTEGSFRCTCGQGYQLSAAK-DQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYR 1152
Query: 710 IMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINE 769
G CED +ECL C R C+NT GS+ C C DG+ L+ ++ C DINE
Sbjct: 1153 ASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCT-----CPDGFQLDDNKTCQDINE 1206
Query: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHT------ 821
C +GE C+NT GSFHC C+ G+++ DG CED+DEC T
Sbjct: 1207 CEHPGLCGPQGE-CLNTEGSFHC----VCQQGFSISADGRTCEDIDECVNNTVCDSHGFC 1261
Query: 822 ----------CQPGF-------------------------LCQNTKGSFYC--------- 837
C GF C+N +GSF C
Sbjct: 1262 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEY 1321
Query: 838 -----QARQRC---MDGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSY- 881
Q R R +D + P+ N D + C ++ P C T G+
Sbjct: 1322 SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW 1381
Query: 882 --TCQRNPL----------ICARGY--------HASDDGTKCVDVNECET-GVHRCGEGQ 920
C+ P +C +G + G D +EC G C G
Sbjct: 1382 GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF 1441
Query: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFL 980
+ PG Y C CK G D C D++EC P C NT GSY C C +
Sbjct: 1442 CLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMV 1499
Query: 981 LAADGKRC-------EDVNECEAQR------------CSQECANIYGSY-QCYCRQGYQL 1020
L A KRC E + E + + CS+ +Y +C C G
Sbjct: 1500 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW 1559
Query: 1021 AEDGHTC--TDIDECAQGAGILCTFR---------------------------------- 1044
C D D+ AQ I T R
Sbjct: 1560 GMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFE 1619
Query: 1045 -----------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN---CS 1084
C+ V Y C C + GY + +C DV+EC + C
Sbjct: 1620 ELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNECDELNNRMSLCK 1678
Query: 1085 EAETCHNIQGSFRCLRFECPPNYVQVSK 1112
A+ C N GS++CL C P YV K
Sbjct: 1679 NAK-CINTDGSYKCL---CLPGYVPSDK 1702
Score = 143 bits (360), Expect = 1e-33
Identities = 92/270 (34%), Positives = 126/270 (46%), Gaps = 54/270 (20%)
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
T+ ++NEC CG G C NLP Y C C G++ R C+D++EC
Sbjct: 870 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 928
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ-ECANIYGSYQC-YCRQG 1017
Q CENT GS+ C C +GF+ + +G C DV+EC C + C N G+++C YC G
Sbjct: 929 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 988
Query: 1018 YQLAEDGHTCTDIDECAQGAG---------------ILCT--FR---------------- 1044
Y++ + G C DIDEC + + CT FR
Sbjct: 989 YRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 1047
Query: 1045 ------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
C N+ GSY C+C +GYT T + + C+D+DEC G N C N +GSFRC
Sbjct: 1048 VCANGDCSNLEGSYMCSC-HKGYTRTPDHKHCRDIDECQQG--NLCVNGQCKNTEGSFRC 1104
Query: 1099 LRFECPPNYVQVSKTKCERTTCHDFLECQN 1128
C Y Q+S K + C D ECQ+
Sbjct: 1105 ---TCGQGY-QLSAAKDQ---CEDIDECQH 1127
Score = 87.4 bits (215), Expect = 7e-17
Identities = 111/486 (22%), Positives = 173/486 (35%), Gaps = 115/486 (23%)
Query: 603 DDQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTC---------------- 644
+D DEC+ +C C NT GS+ C C+ GF DG+ C
Sbjct: 1244 EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 1301
Query: 645 ---RPEGH-------PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC----KDNGPC- 689
EG Q +P +S S + P + C D C
Sbjct: 1302 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1361
Query: 690 --------KQVCSTVGGSAI---CSCFP-----------------GY------AIMADGV 715
KQ C G+ C FP G+ + A G
Sbjct: 1362 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1421
Query: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADG-YILNAHRKCVDINECVTDL 774
+ +D DECL+ + + FC+NT + C C G Y +C D++EC D
Sbjct: 1422 NYKDADECLLFGQEICKNGFCLNTRPGYECY-----CKQGTYYDPVKLQCFDMDEC-QDP 1475
Query: 775 HTCSRGEHCVNTLGSFHCY----KALTCEPGYALKDGEC-EDVDECAMGTHTC----QPG 825
+C G+ CVNT GS++C+ L ++ E E ++E + C
Sbjct: 1476 SSCIDGQ-CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDE 1534
Query: 826 FLCQNT---KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFS--------- 873
++C K + Y + C+ G + + + ++ C +
Sbjct: 1535 YVCSRPLVGKQTTYTECC--CLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRD 1592
Query: 874 -CINTVGSYTCQRNPLICARGYHASDD---GTKCVDVNECETGVHRCGEGQVCHNLPGSY 929
++ YT + +P + S + +C +N CE G C + Y
Sbjct: 1593 ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR--------CVRVQEGY 1644
Query: 930 RCDCKAGFQRDAFGRGCIDVNECWASPGR--LCQHT-CENTLGSYRCSCASGFLLAADGK 986
CDC G+ D C+DVNEC R LC++ C NT GSY+C C G++ +
Sbjct: 1645 TCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPN 1704
Query: 987 RCEDVN 992
C +N
Sbjct: 1705 YCTPLN 1710
Score = 79.7 bits (195), Expect = 2e-14
Identities = 161/704 (22%), Positives = 233/704 (33%), Gaps = 155/704 (22%)
Query: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 1034 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 1088
Query: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 1089 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 1148
Query: 563 EVRRPP-------------EPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL 609
+ R E + +R AG + +L ++ D +EC
Sbjct: 1149 QGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE 1208
Query: 610 LLPGELC--QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL----KS 663
PG LC Q C+NT GS+HC C GFS+ DGRTC
Sbjct: 1209 H-PG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG 1266
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPG---YAIMA 712
F + P C D C+ + C V GS +C C Y+ M
Sbjct: 1267 SFRCLCYQGFQAP-QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 1325
Query: 713 DGVSC--------------EDQDECLMGAHDCS----------RRQFCVNTLGS------ 742
E++ EC +D S +Q C T G+
Sbjct: 1326 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC 1385
Query: 743 --FYC-----VNHTVLC--ADGYILNAHRKCV-------DINECVTDLHTCSRGEHCVNT 786
F C T +C G++ D +EC+ + C+NT
Sbjct: 1386 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1445
Query: 787 LGSFHCYKALTCEPG--YALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCM 844
+ CY C+ G Y +C D+DEC +C G C NT+GS+ C +
Sbjct: 1446 RPGYECY----CKQGTYYDPVKLQCFDMDEC-QDPSSCIDG-QCVNTEGSYNCFCTHPMV 1499
Query: 845 DGFLQDPEGNCV-------DINECTSLSEPCRPGFSCINTVGSYTCQRNPLI-------- 889
L E C+ I E + C S Y C R PL+
Sbjct: 1500 ---LDASEKRCIRPAESNEQIEETDVYQDLCWEHLS-----DEYVCSR-PLVGKQTTYTE 1550
Query: 890 --CARG-----------YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 936
C G SDD + ++ TG + + Y +
Sbjct: 1551 CCCLYGEAWGMQCALCPLKDSDDYAQLCNIPV--TGRRQPYGRDALVDFSEQYTPEADPY 1608
Query: 937 FQRDAFGRGC--IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNE 993
F +D F + EC G C++ C Y C C G+ L C DVNE
Sbjct: 1609 FIQDRFLNSFEELQAEECGILNG--CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNE 1666
Query: 994 CEAQR-----CSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDID 1031
C+ C +C N GSY+C C GY ++ + CT ++
Sbjct: 1667 CDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 870 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 910
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 573 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 631
Query: 911 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 959
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 632 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 688
Query: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCE 989
C H L C C+ G A G CE
Sbjct: 689 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 715
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 786 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 563 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 614
Query: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 904
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 615 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 666
Score = 40.8 bits (94), Expect = 0.008
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 21/96 (21%)
Query: 722 ECLMGAHDCSRRQFCVNTLG---------------SFYCVNHTVLCADGYILNAHRKCVD 766
+C S+++ C T+G S++ N + C GY + C D
Sbjct: 567 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 626
Query: 767 INECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
INEC C GE C+NT+GS+ C TC+ G+
Sbjct: 627 INECQLQ-GVCPNGE-CLNTMGSYRC----TCKIGF 656
Score = 39.3 bits (90), Expect = 0.023
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 969
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 562 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 610
Query: 970 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 1018
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 611 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 37.4 bits (85), Expect = 0.089
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 954 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 1013
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 571 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 611
Query: 1014 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1056
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 612 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 652
Score = 34.7 bits (78), Expect = 0.58
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 626 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 682
Query: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
S + + + + L + C K GP + C G +A PG
Sbjct: 683 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 731
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 283 bits (725), Expect = 5e-76
Identities = 211/628 (33%), Positives = 294/628 (46%), Gaps = 85/628 (13%)
Query: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 369 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 424
Query: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 425 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 484
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 485 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 534
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDQ 720
S SQV + P + + N C N C + C C+ GY C D
Sbjct: 535 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSR 779
DEC H CS+ + C NT GSF C+ C G++ + C+D++EC+ C
Sbjct: 592 DECTQVQHLCSQGR-CENTEGSFLCI-----CPAGFMASEEGTNCIDVDECLRP-DVCGE 644
Query: 780 GEHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
G HCVNT+G+F C C+ GY + + G CED+DEC + TC P C N+ GS+ C
Sbjct: 645 G-HCVNTVGAFRCE---YCDSGYRMTQRGRCEDIDEC-LNPSTC-PDEQCVNSPGSYQCV 698
Query: 839 ARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASD 898
C +GF + G C+D++EC C G C N GSY C C +GY +
Sbjct: 699 P---CTEGF-RGWNGQCLDVDECLE-PNVCANG-DCSNLEGSYMCS-----CHKGYTRTP 747
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 958
D C D++EC+ G + C GQ C N GS+RC C G+Q A C D++EC
Sbjct: 748 DHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC--QHRH 803
Query: 959 LCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYC 1014
LC H C NT GS++C C G+ + G CED+NEC + C + +C N GSY C C
Sbjct: 804 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTC 863
Query: 1015 RQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
G+QL +D TC DI+EC CLN GS+ C C +QG++++A+GR+C+D+D
Sbjct: 864 PDGFQL-DDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVC-QQGFSISADGRTCEDID 921
Query: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFE 1102
EC T C C N GSFRCL ++
Sbjct: 922 ECVNNT-VCDSHGFCDNTAGSFRCLCYQ 948
Score = 222 bits (565), Expect = 2e-57
Identities = 185/588 (31%), Positives = 238/588 (40%), Gaps = 110/588 (18%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCA-CFPGFSLQDDGR-----------TCRPEGHPP 651
D DECL P + C+NTVG++ C C G+ + GR TC E
Sbjct: 632 DVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVN 690
Query: 652 QPEAPQEPALKSEFSQVASNTIPLP-LPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAI 710
P + Q F + + +PN C + CS + GS +CSC GY
Sbjct: 691 SPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-----CSNLEGSYMCSCHKGYTR 745
Query: 711 MADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINE 769
D C D DEC G + C Q C NT GSF C C GY L+A + +C DI+E
Sbjct: 746 TPDHKHCRDIDECQQG-NLCVNGQ-CKNTEGSFRCT-----CGQGYQLSAAKDQCEDIDE 798
Query: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFL 827
C H C+ G+ C NT GSF C C+ GY CED++EC CQ G
Sbjct: 799 C-QHRHLCAHGQ-CRNTEGSFQC----VCDQGYRASGLGDHCEDINECLEDKSVCQRGD- 851
Query: 828 CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 887
C NT GS+ C C DGF D C DINEC C P C+NT GS+ C
Sbjct: 852 CINTAGSYDCT----CPDGFQLDDNKTCQDINECEHPGL-CGPQGECLNTEGSFHC---- 902
Query: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 947
+C +G+ S DG C D++EC C C N GS+RC C GFQ G+GC+
Sbjct: 903 -VCQQGFSISADGRTCEDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 960
Query: 948 DVNECWASPGRLCQHTCENTLGSYRCSCA-----------------SGFLLAADGKRCED 990
DVNEC G + CEN GS+ C CA S L + E+
Sbjct: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
Query: 991 VNEC-----EAQRCSQECANIYGSYQCYCRQGYQLAED---------------------- 1023
EC +A C A +C C G ++
Sbjct: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGK 1080
Query: 1024 -------------GHTCTDIDECAQ-GAGILCTFRCLNVPGSYQCACPEQGYTMTANGRS 1069
G D DEC G I CLN Y+C C +QG
Sbjct: 1081 GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYC-KQGTYYDPVKLQ 1139
Query: 1070 CKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER 1117
C D+DEC +C + + C N +GS+ C F P + S+ +C R
Sbjct: 1140 CFDMDECQ-DPSSCIDGQ-CVNTEGSYNC--FCTHPMVLDASEKRCIR 1183
Score = 154 bits (388), Expect = 7e-37
Identities = 234/988 (23%), Positives = 323/988 (32%), Gaps = 309/988 (31%)
Query: 377 PRDPVKPSPHNILSTSL--------PDAAWIPPTREVPR-----------KPQVLP---- 413
P P K P L+ S P+ A PP +E+P +PQ+ P
Sbjct: 446 PPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGIST 505
Query: 414 -HSH-------VEEDTDPNSVHSIPRSSPEGSTKDLIET-------------CCAAG--- 449
H H +E+ + P V P +S +++ + T C AG
Sbjct: 506 IHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCI 565
Query: 450 -------------------QQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCM 490
Q+ +D DEC ++ ++ T C+ C
Sbjct: 566 NLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCI-------CP 618
Query: 491 AGVLGAKEGETCGAEDN----DSCG-------ISLYKQCCDCCGLGLRVRAEGQSCESNP 539
AG + ++EG C D D CG + ++ C+ C G R+ G+ CE
Sbjct: 619 AGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFR--CEYCDSGYRMTQRGR-CEDID 675
Query: 540 NLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNS 599
P S C E+ V P P G+
Sbjct: 676 ECLNP------STCPDEQC-----VNSPGSYQCVPCTEGFRGWNGQCL------------ 712
Query: 600 LPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
D DECL P C N GSY C+C G++ D + CR Q
Sbjct: 713 ----DVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG 767
Query: 660 ALKS---EFSQVASNTIPLPLPQPNTCKDNGPCKQ-------VCSTVGGSAICSCFPGYA 709
K+ F L + + C+D C+ C GS C C GY
Sbjct: 768 QCKNTEGSFRCTCGQGYQLSAAK-DQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYR 826
Query: 710 IMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINE 769
G CED +ECL C R C+NT GS+ C C DG+ L+ ++ C DINE
Sbjct: 827 ASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCT-----CPDGFQLDDNKTCQDINE 880
Query: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHT------ 821
C +GE C+NT GSFHC C+ G+++ DG CED+DEC T
Sbjct: 881 CEHPGLCGPQGE-CLNTEGSFHC----VCQQGFSISADGRTCEDIDECVNNTVCDSHGFC 935
Query: 822 ----------CQPGF-------------------------LCQNTKGSFYC--------- 837
C GF C+N +GSF C
Sbjct: 936 DNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEY 995
Query: 838 -----QARQRC---MDGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSY- 881
Q R R +D + P+ N D + C ++ P C T G+
Sbjct: 996 SPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW 1055
Query: 882 --TCQRNPL----------ICARGY--------HASDDGTKCVDVNECET-GVHRCGEGQ 920
C+ P +C +G + G D +EC G C G
Sbjct: 1056 GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF 1115
Query: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFL 980
+ PG Y C CK G D C D++EC P C NT GSY C C +
Sbjct: 1116 CLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMV 1173
Query: 981 LAADGKRC-------EDVNECEAQR------------CSQECANIYGSY-QCYCRQGYQL 1020
L A KRC E + E + + CS+ +Y +C C G
Sbjct: 1174 LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW 1233
Query: 1021 AEDGHTC--TDIDECAQGAGILCTFR---------------------------------- 1044
C D D+ AQ I T R
Sbjct: 1234 GMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFE 1293
Query: 1045 -----------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN---CS 1084
C+ V Y C C + GY + +C DV+EC + C
Sbjct: 1294 ELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNECDELNNRMSLCK 1352
Query: 1085 EAETCHNIQGSFRCLRFECPPNYVQVSK 1112
A+ C N GS++CL C P YV K
Sbjct: 1353 NAK-CINTDGSYKCL---CLPGYVPSDK 1376
Score = 143 bits (360), Expect = 1e-33
Identities = 92/270 (34%), Positives = 126/270 (46%), Gaps = 54/270 (20%)
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
T+ ++NEC CG G C NLP Y C C G++ R C+D++EC
Sbjct: 544 TQVTEINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ-ECANIYGSYQC-YCRQG 1017
Q CENT GS+ C C +GF+ + +G C DV+EC C + C N G+++C YC G
Sbjct: 603 QGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSG 662
Query: 1018 YQLAEDGHTCTDIDECAQGAG---------------ILCT--FR---------------- 1044
Y++ + G C DIDEC + + CT FR
Sbjct: 663 YRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 721
Query: 1045 ------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
C N+ GSY C+C +GYT T + + C+D+DEC G N C N +GSFRC
Sbjct: 722 VCANGDCSNLEGSYMCSC-HKGYTRTPDHKHCRDIDECQQG--NLCVNGQCKNTEGSFRC 778
Query: 1099 LRFECPPNYVQVSKTKCERTTCHDFLECQN 1128
C Y Q+S K + C D ECQ+
Sbjct: 779 ---TCGQGY-QLSAAKDQ---CEDIDECQH 801
Score = 87.4 bits (215), Expect = 7e-17
Identities = 111/486 (22%), Positives = 173/486 (35%), Gaps = 115/486 (23%)
Query: 603 DDQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTC---------------- 644
+D DEC+ +C C NT GS+ C C+ GF DG+ C
Sbjct: 918 EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 975
Query: 645 ---RPEGH-------PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC----KDNGPC- 689
EG Q +P +S S + P + C D C
Sbjct: 976 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1035
Query: 690 --------KQVCSTVGGSAI---CSCFP-----------------GY------AIMADGV 715
KQ C G+ C FP G+ + A G
Sbjct: 1036 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1095
Query: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADG-YILNAHRKCVDINECVTDL 774
+ +D DECL+ + + FC+NT + C C G Y +C D++EC D
Sbjct: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECY-----CKQGTYYDPVKLQCFDMDEC-QDP 1149
Query: 775 HTCSRGEHCVNTLGSFHCY----KALTCEPGYALKDGEC-EDVDECAMGTHTC----QPG 825
+C G+ CVNT GS++C+ L ++ E E ++E + C
Sbjct: 1150 SSCIDGQ-CVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDE 1208
Query: 826 FLCQNT---KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFS--------- 873
++C K + Y + C+ G + + + ++ C +
Sbjct: 1209 YVCSRPLVGKQTTYTECC--CLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRD 1266
Query: 874 -CINTVGSYTCQRNPLICARGYHASDD---GTKCVDVNECETGVHRCGEGQVCHNLPGSY 929
++ YT + +P + S + +C +N CE G C + Y
Sbjct: 1267 ALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR--------CVRVQEGY 1318
Query: 930 RCDCKAGFQRDAFGRGCIDVNECWASPGR--LCQHT-CENTLGSYRCSCASGFLLAADGK 986
CDC G+ D C+DVNEC R LC++ C NT GSY+C C G++ +
Sbjct: 1319 TCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPN 1378
Query: 987 RCEDVN 992
C +N
Sbjct: 1379 YCTPLN 1384
Score = 79.7 bits (195), Expect = 2e-14
Identities = 161/704 (22%), Positives = 233/704 (33%), Gaps = 155/704 (22%)
Query: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 708 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 762
Query: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 822
Query: 563 EVRRPP-------------EPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL 609
+ R E + +R AG + +L ++ D +EC
Sbjct: 823 QGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE 882
Query: 610 LLPGELC--QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL----KS 663
PG LC Q C+NT GS+HC C GFS+ DGRTC
Sbjct: 883 H-PG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG 940
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPG---YAIMA 712
F + P C D C+ + C V GS +C C Y+ M
Sbjct: 941 SFRCLCYQGFQAP-QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 999
Query: 713 DGVSC--------------EDQDECLMGAHDCS----------RRQFCVNTLGS------ 742
E++ EC +D S +Q C T G+
Sbjct: 1000 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC 1059
Query: 743 --FYC-----VNHTVLC--ADGYILNAHRKCV-------DINECVTDLHTCSRGEHCVNT 786
F C T +C G++ D +EC+ + C+NT
Sbjct: 1060 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT 1119
Query: 787 LGSFHCYKALTCEPG--YALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCM 844
+ CY C+ G Y +C D+DEC +C G C NT+GS+ C +
Sbjct: 1120 RPGYECY----CKQGTYYDPVKLQCFDMDEC-QDPSSCIDG-QCVNTEGSYNCFCTHPMV 1173
Query: 845 DGFLQDPEGNCV-------DINECTSLSEPCRPGFSCINTVGSYTCQRNPLI-------- 889
L E C+ I E + C S Y C R PL+
Sbjct: 1174 ---LDASEKRCIRPAESNEQIEETDVYQDLCWEHLS-----DEYVCSR-PLVGKQTTYTE 1224
Query: 890 --CARG-----------YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 936
C G SDD + ++ TG + + Y +
Sbjct: 1225 CCCLYGEAWGMQCALCPLKDSDDYAQLCNIPV--TGRRQPYGRDALVDFSEQYTPEADPY 1282
Query: 937 FQRDAFGRGC--IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNE 993
F +D F + EC G C++ C Y C C G+ L C DVNE
Sbjct: 1283 FIQDRFLNSFEELQAEECGILNG--CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNE 1340
Query: 994 CEAQR-----CSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDID 1031
C+ C +C N GSY+C C GY ++ + CT ++
Sbjct: 1341 CDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 870 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 910
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 247 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 305
Query: 911 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 959
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 306 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 362
Query: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCE 989
C H L C C+ G A G CE
Sbjct: 363 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 389
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 786 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 237 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 288
Query: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 904
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 289 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 340
Score = 40.8 bits (94), Expect = 0.008
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 21/96 (21%)
Query: 722 ECLMGAHDCSRRQFCVNTLG---------------SFYCVNHTVLCADGYILNAHRKCVD 766
+C S+++ C T+G S++ N + C GY + C D
Sbjct: 241 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD 300
Query: 767 INECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
INEC C GE C+NT+GS+ C TC+ G+
Sbjct: 301 INECQLQ-GVCPNGE-CLNTMGSYRC----TCKIGF 330
Score = 39.3 bits (90), Expect = 0.023
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 969
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 236 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 284
Query: 970 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 1018
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 285 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.4 bits (85), Expect = 0.089
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 954 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 1013
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 245 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 285
Query: 1014 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1056
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 286 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 326
Score = 34.7 bits (78), Expect = 0.58
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 356
Query: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
S + + + + L + C K GP + C G +A PG
Sbjct: 357 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 283 bits (723), Expect = 9e-76
Identities = 241/843 (28%), Positives = 336/843 (39%), Gaps = 214/843 (25%)
Query: 446 CAAGQQWA-----IDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKE 498
CAAG + + +D +ECLEIP NVC CV C+ G +++
Sbjct: 1878 CAAGFKLSPNGACVDRNECLEIP------NVC---SHGLCVDLQGSYQCICHNGFKASQD 1928
Query: 499 GETCGAEDN---DSCG-------ISLYKQCC----------DCCGLGLRVRAEGQSCESN 538
C D CG + Y C DC + GQ C +
Sbjct: 1929 QTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG 1988
Query: 539 P------------NLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGRE 586
N GY +C + E + +P + +P E + R
Sbjct: 1989 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG-------SCSPGTCQNLEGSFRC 2041
Query: 587 ALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP 646
G E + N + D +EC P C NT G + C C PGF L D+GR C
Sbjct: 2042 ICPPGYEVKSENCI---DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Query: 647 E-------------------------------------GHPPQPEAPQEPALKSEFSQVA 669
G P + + +
Sbjct: 2099 TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYG 2158
Query: 670 SNTIPL---PLPQPNTCKDN-GPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
T+P N C ++ G C C GS C C GY + GV C D DEC
Sbjct: 2159 HGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECS 2218
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCV 784
+G + C C N +GSF C C +G+ C DINEC + C+ C+
Sbjct: 2219 IG-NPCGNGT-CTNVIGSFECN-----CNEGFEPGPMMNCEDINECAQNPLLCA--FRCM 2269
Query: 785 NTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQ 841
NT GS+ C TC GYAL++ + C+D+DECA G H C+ G +C+N G+F C
Sbjct: 2270 NTFGSYEC----TCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC---- 2321
Query: 842 RCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
C G + P+G CVD NEC + C G C+N +GSY C+ C G+ +S G
Sbjct: 2322 ICPPGMARRPDGEGCVDENECRTKPGICENG-RCVNIIGSYRCE-----CNEGFQSSSSG 2375
Query: 901 TKCVDVNE----------------------------CETG---VHRC------GEGQ--- 920
T+C+D + C+ G H+C G Q
Sbjct: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK 2435
Query: 921 VCHNLPG----------------------------SYRCDCKAGFQRDAFGRGCIDVNEC 952
+C + PG S+RC CK G+ D G CID++EC
Sbjct: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
Query: 953 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSY 1010
SP + C + C+NT GSY+CSC G++L DGK C+D++EC+ ++ C C N G +
Sbjct: 2496 SQSP-KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
Query: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR--CLNVPGSYQCACPEQGYTMTANGR 1068
C C G+ + C D +EC LC + C N PGS+ C C ++G+++ A G
Sbjct: 2555 TCKCPPGF--TQHHTACIDNNECGSQPS-LCGAKGICQNTPGSFSCEC-QRGFSLDATGL 2610
Query: 1069 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQN 1128
+C+DVDEC G H C C NI G +RC CP Y+Q + C D EC N
Sbjct: 2611 NCEDVDECD-GNHRCQHG--CQNILGGYRC---GCPQGYIQ----HYQWNQCVDENECSN 2660
Query: 1129 SPA 1131
A
Sbjct: 2661 PNA 2663
Score = 276 bits (706), Expect = 9e-74
Identities = 226/758 (29%), Positives = 312/758 (41%), Gaps = 155/758 (20%)
Query: 445 CCAAGQQWAIDNDECLEIPESGTED---------------------------NVCRTAQR 477
CCA G W + +EC P+ GT++ N C+
Sbjct: 1026 CCAVGAAWGTECEEC---PKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG 1082
Query: 478 HC----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
C C + + C A + E D D C IS D CG G+ V G
Sbjct: 1083 MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP-----DLCGSGICVNTPG- 1136
Query: 534 SCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTE 593
S E GY +M+ C + + E R P V+ E + + LG E
Sbjct: 1137 SFECECFEGYESGFMMMKNC-----MDIDECERNPLLCRGGTCVN-TEGSFQCDCPLGHE 1190
Query: 594 AELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
P+ D +EC L LC++ C+N +G+Y C+C PG+ D + C
Sbjct: 1191 LS-PSREDCVDINECSL-SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-------- 1240
Query: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
+ + I NG C C+ GS CSC GYA+M
Sbjct: 1241 -------------TDIDECMIM-----------NGGCDTQCTNSEGSYECSCSEGYALMP 1276
Query: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECV 771
DG SC D DEC C Q C N G + C LC DG++ + K C+D+NEC
Sbjct: 1277 DGRSCADIDECENNPDICDGGQ-CTNIPGEYRC-----LCYDGFMASMDMKTCIDVNECD 1330
Query: 772 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQ 829
+ + C GE C NT GSF C+ C+ GY++K G C DVDEC +G H C C
Sbjct: 1331 LNSNICMFGE-CENTKGSFICH----CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCL 1385
Query: 830 NTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
N GSF C R+ + ++ C+D++EC++ + C C+NT GSY C
Sbjct: 1386 NIPGSFKCSCREGWIGNGIK-----CIDLDECSNGTHQCSINAQCVNTPGSYRC-----A 1435
Query: 890 CARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV 949
C+ G+ + DG C DV+EC ++ C GQ C N+PG+YRC+C+ GF + R C D+
Sbjct: 1436 CSEGF--TGDGFTCSDVDECAENINLCENGQ-CLNVPGAYRCECEMGFTPASDSRSCQDI 1492
Query: 950 NECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRC-SQECANI 1006
+EC S +C TC N G + C C G+ L G C D++EC + C + C N
Sbjct: 1493 DEC--SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNT 1550
Query: 1007 YGSYQCYCRQGYQLAEDGHTCTD--IDEC-----AQGAGILCTFRCLNVPGSYQCACPEQ 1059
G Y+C C +QL G C D + C +G G L + V S C
Sbjct: 1551 PGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSL 1610
Query: 1060 G------------------YTMTANGRS---------CKDVDECALGTHNCSEAETCHNI 1092
G YT+ G +D+DEC C + C N
Sbjct: 1611 GKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC-QGGNCINT 1669
Query: 1093 QGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
GSF+C ECP Y T+ C D EC P
Sbjct: 1670 FGSFQC---ECPQGYYLSEDTR----ICEDIDECFAHP 1700
Score = 260 bits (664), Expect = 6e-69
Identities = 205/717 (28%), Positives = 288/717 (40%), Gaps = 142/717 (19%)
Query: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
N G+ + + C CC LG +A G CE+ P + + + EG P + +
Sbjct: 1594 NTEIGVGVSRSSC-CCSLG---KAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILE 1649
Query: 567 PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD-----DQDECLLLPGELCQHLCI 621
+ + + S E L D D DEC PG C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
Query: 622 NTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL------ 675
NT+G+Y C C P + + G C + + +S N +P
Sbjct: 1710 NTLGNYTCICPPEYMQVNGGHNCM--------DMRKSFCYRSYNGTTCENELPFNVTKRM 1761
Query: 676 ----------------PLPQPNTCK---------------------DNGPCKQ------- 691
P P P T D CK+
Sbjct: 1762 CCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICAN 1821
Query: 692 -VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTV 750
VC GS C C G++ + CED DEC G + C R C+N+ GS+ C
Sbjct: 1822 GVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE---- 1877
Query: 751 LCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE-- 808
CA G+ L+ + CVD NEC+ + CS G CV+ GS+ C C G+ +
Sbjct: 1878 -CAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCI----CHNGFKASQDQTM 1931
Query: 809 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL-SEP 867
C DVDEC H C G C+NT GS+ C C GF +C+DI+EC+S +
Sbjct: 1932 CMDVDECER--HPCGNG-TCKNTVGSYNCL----CYPGFELTHNNDCLDIDECSSFFGQV 1984
Query: 868 CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPG 927
CR G C N +GS+ C +C GY + DG C+D NEC C G C NL G
Sbjct: 1985 CRNG-RCFNEIGSFKC-----LCNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEG 2037
Query: 928 SYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKR 987
S+RC C G++ + CID+NEC P +C NT G ++C C GF+L+ +G+R
Sbjct: 2038 SFRCICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRR 2095
Query: 988 CEDVNEC------EAQRCSQE-----------CANIYG----------------SYQCYC 1014
C D + E +CS C+ + G ++Q C
Sbjct: 2096 CFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLC 2155
Query: 1015 RQGYQLAEDGH-TCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1073
G+ H T D++EC + GI +C+N GS++C CP GY + G C D
Sbjct: 2156 PYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECP-MGYNLDYTGVRCVDT 2214
Query: 1074 DECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
DEC++G + C TC N+ GSF C C + CE D EC +P
Sbjct: 2215 DECSIG-NPCGNG-TCTNVIGSFEC---NCNEGFEPGPMMNCE-----DINECAQNP 2261
Score = 237 bits (604), Expect = 6e-62
Identities = 169/484 (34%), Positives = 224/484 (46%), Gaps = 62/484 (12%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D++EC PG C+N +GSY C C GF G C + +
Sbjct: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR-----QGLCFAEVLQ 2392
Query: 664 EFSQVASNTIPLPLPQPNTCKDNG-----PCKQVCSTVGGSA---ICSCFPGYAIMADGV 715
Q+AS++ L + + C D G C ++C G + IC PGY DG
Sbjct: 2393 TICQMASSSRNL-VTKSECCCDGGRGWGHQC-ELCPLPGTAQYKKICPHGPGYT--TDG- 2447
Query: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDL 774
D DEC + + C+ Q C+NT+GSF C C GY + + C+D++EC
Sbjct: 2448 --RDIDECKVMPNLCTNGQ-CINTMGSFRC-----FCKVGYTTDISGTSCIDLDECSQSP 2499
Query: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQNTK 832
C+ C NT GS+ C +C GY L+ DG+ C+D+DEC H CQ FLC NT
Sbjct: 2500 KPCNY--ICKNTEGSYQC----SCPRGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNTL 2551
Query: 833 GSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
G F C +C GF Q C+D NEC S C C NT GS++C+ C R
Sbjct: 2552 GGFTC----KCPPGFTQHHTA-CIDNNECGSQPSLCGAKGICQNTPGSFSCE-----CQR 2601
Query: 893 GYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 952
G+ G C DV+EC+ G HRC G C N+ G YRC C G+ + C+D NEC
Sbjct: 2602 GFSLDATGLNCEDVDECD-GNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENEC 2658
Query: 953 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSY 1010
++P +C NTLGSY+C+C SGF C DVNEC + + C+ C+N G Y
Sbjct: 2659 -SNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGY 2717
Query: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGI-LCTFRCLNVPGSYQCA-CPEQGYTMTANGR 1068
C C GY GH C G G + L+ + A PE Y NG
Sbjct: 2718 LCGCPPGYYRVGQGH-------CVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGY 2770
Query: 1069 SCKD 1072
S KD
Sbjct: 2771 SKKD 2774
Score = 234 bits (597), Expect = 4e-61
Identities = 221/806 (27%), Positives = 299/806 (37%), Gaps = 205/806 (25%)
Query: 453 AIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC-- 510
A+D DEC EIP +C C++ + C + ED D C
Sbjct: 1806 AVDIDECKEIP------GICANG---VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSN 1856
Query: 511 GISLYKQCCDC----------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEP 558
G +L ++ DC C G ++ G + N L P C+H + +G
Sbjct: 1857 GDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQ 1916
Query: 559 LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGT--------------EAELPNSLPGDD 604
I + + V E E R GT EL ++ D
Sbjct: 1917 CICHNGFKASQDQTMCMDVDECE---RHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLD 1973
Query: 605 QDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
DEC G++C++ C N +GS+ C C G+ L DG+ C
Sbjct: 1974 IDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC------------------- 2014
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDEC 723
+ +N + P +C C + GS C C PGY + ++ +C D +EC
Sbjct: 2015 ----IDTNEC---VALPGSCSPG-----TCQNLEGSFRCICPPGYEVKSE--NCIDINEC 2060
Query: 724 LMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINE--CVTDLHT--CS 778
+ C C NT G F C LC G++L+ + R+C D + C T+ CS
Sbjct: 2061 DEDPNICLFGS-CTNTPGGFQC-----LCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCS 2114
Query: 779 RGEHCVNTLGSFHCYK------ALTCEPGYALKDGEC--------------------EDV 812
+ T C K CE KD E EDV
Sbjct: 2115 VPKAFNTTKAKCCCSKMPGEGWGDPCE--LCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
Query: 813 DECAMGTHTCQPGFLCQNTKGSFYCQARQ---------RCMD------------------ 845
+EC C G C NT GSF C+ RC+D
Sbjct: 2173 NECLESPGICSNG-QCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNV 2231
Query: 846 ----------GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYH 895
GF P NC DINEC P F C+NT GSY C C GY
Sbjct: 2232 IGSFECNCNEGFEPGPMMNCEDINECA--QNPLLCAFRCMNTFGSYEC-----TCPIGYA 2284
Query: 896 ASDDGTKCVDVNECETGVHRC-GEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 954
+D C D++EC G+H C G +C NL G++ C C G R G GC+D NEC
Sbjct: 2285 LREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRT 2344
Query: 955 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE--CEAQRCSQEC------ANI 1006
PG C N +GSYRC C GF ++ G C D + C A+ C N+
Sbjct: 2345 KPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNL 2404
Query: 1007 YGSYQCYCRQGYQLAEDGHTC-------------------------TDIDECAQGAGILC 1041
+C C G GH C DIDEC +
Sbjct: 2405 VTKSECCCDGGRGW---GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCT 2461
Query: 1042 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1101
+C+N GS++C C + GYT +G SC D+DEC+ C+ C N +GS++C
Sbjct: 2462 NGQCINTMGSFRCFC-KVGYTTDISGTSCIDLDECSQSPKPCN--YICKNTEGSYQC--- 2515
Query: 1102 ECPPNYVQVSKTKCERTTCHDFLECQ 1127
CP YV K TC D ECQ
Sbjct: 2516 SCPRGYVLQEDGK----TCKDLDECQ 2537
Score = 232 bits (591), Expect = 2e-60
Identities = 225/829 (27%), Positives = 318/829 (38%), Gaps = 190/829 (22%)
Query: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVL 494
+T + C AG + D C++ E T N+C C++ C+ G +
Sbjct: 593 NTDGSFQCICNAGFELTTDGKNCVDHDEC-TTTNMCLNGM---CINEDGSFKCICKPGFV 648
Query: 495 GAKEGETCGAEDNDSC---GISLYKQC--------CDCCGLGLRVRAEGQSCESNPNLGY 543
A G C D D C GI + C CDC GL V +G+ C
Sbjct: 649 LAPNGRYC--TDVDECQTPGICMNGHCINSEGSFRCDCPP-GLAVGMDGRVCVDTHMRST 705
Query: 544 PCNHVMLSCCEGEEPLIVPEVR-----------RPPEPAAAPRRVSEAEMAGREALSLGT 592
+ C P V + P +P A + AE G + +G
Sbjct: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAK---NSAEFHGLCSSGVGI 762
Query: 593 EAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
+ G D +EC L P +C N GSY C C G+ GR C
Sbjct: 763 TVD------GRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-------- 808
Query: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
+ + N + C DNG +C GS C+C PGY
Sbjct: 809 ----------IDIDECLVNRL--------LC-DNG----LCRNTPGSYSCTCPPGYVFRT 845
Query: 713 DGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDI---- 767
+ +CED +EC ++ C C N LGSF C C+ G L++ C+D
Sbjct: 846 ETETCEDINEC--ESNPCVNGA-CRNNLGSFNCE-----CSPGSKLSSTGLICIDSLKGT 897
Query: 768 -------NECVTDLHTCSRGEHCVNTLGSF------HCYKALTCEPGYA-LKDGECEDVD 813
+ C +++ + C TLG+ C C G A +K CEDV+
Sbjct: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVN 957
Query: 814 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDI-------------- 858
EC + C P C N+KGSF+C+ C +G D G C+DI
Sbjct: 958 ECEVFPGVC-PNGRCVNSKGSFHCE----CPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
Query: 859 ----------------------NECTSLSEP--------CRPGFSCINTVGSYT------ 882
EC +P C G N T
Sbjct: 1013 IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYK 1072
Query: 883 ----CQRNPLICARGYHASDDGT-KC---------------VDVNECETGVHRCGEGQVC 922
C+ P +C G + G+ KC D++EC CG G +C
Sbjct: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSG-IC 1131
Query: 923 HNLPGSYRCDCKAGFQRD-AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 981
N PGS+ C+C G++ + C+D++EC +P TC NT GS++C C G L
Sbjct: 1132 VNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL 1191
Query: 982 AADGKRCEDVNECEA--QRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 1038
+ + C D+NEC C + +C N+ G+YQC C GYQ D CTDIDEC G
Sbjct: 1192 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 1251
Query: 1039 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
C +C N GSY+C+C E GY + +GRSC D+DEC C + C NI G +RC
Sbjct: 1252 -GCDTQCTNSEGSYECSCSE-GYALMPDGRSCADIDECENNPDICDGGQ-CTNIPGEYRC 1308
Query: 1099 LRFE------CPPNYVQVSKTKCERTTCHDFLECQNSPAR-ITHYQLNF 1140
L ++ + V++ C F EC+N+ I H QL +
Sbjct: 1309 LCYDGFMASMDMKTCIDVNECDLNSNICM-FGECENTKGSFICHCQLGY 1356
Score = 203 bits (516), Expect = 9e-52
Identities = 153/467 (32%), Positives = 211/467 (45%), Gaps = 79/467 (16%)
Query: 696 VGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADG 755
VGG+ + + G I + + D C A+ C + C+ T+ S+ C C G
Sbjct: 471 VGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGR-CIPTVSSYRCE-----CNMG 524
Query: 756 YILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD 813
Y +A+ C+D++EC ++ C+ G+ CVNT GS++C C G+ + C D+D
Sbjct: 525 YKQDANGDCIDVDECTSN--PCTNGD-CVNTPGSYYC----KCHAGFQRTPTKQACIDID 577
Query: 814 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGF 872
EC C+ G C NT GSF C C GF +G NCVD +ECT+ + C G
Sbjct: 578 ECIQNGVLCKNG-RCVNTDGSFQCI----CNAGFELTTDGKNCVDHDECTT-TNMCLNGM 631
Query: 873 SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRC 931
CIN GS+ C IC G+ + +G C DV+EC+T G+ C G C N GS+RC
Sbjct: 632 -CINEDGSFKC-----ICKPGFVLAPNGRYCTDVDECQTPGI--CMNGH-CINSEGSFRC 682
Query: 932 DCKAGFQRDAFGRGCIDVNE--------------------------CWASP----GRLCQ 961
DC G GR C+D + C A+P G CQ
Sbjct: 683 DCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQ 742
Query: 962 HTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQE-CANIYGSYQCYCRQGY 1018
+ C+SG + DG+ D+NEC + C+ C N+ GSY+C C GY
Sbjct: 743 PCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCNSGY 799
Query: 1019 QLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECAL 1078
+ G C DIDEC + C N PGSY C CP GY +C+D++EC
Sbjct: 800 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCP-PGYVFRTETETCEDINECE- 857
Query: 1079 GTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLE 1125
++ C C N GSF C EC P SK C D L+
Sbjct: 858 -SNPCVNG-ACRNNLGSFNC---ECSPG----SKLSSTGLICIDSLK 895
Score = 197 bits (502), Expect = 4e-50
Identities = 154/528 (29%), Positives = 209/528 (39%), Gaps = 106/528 (20%)
Query: 604 DQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC P C + C+NT GSY+C C GF + C
Sbjct: 535 DVDECTSNP---CTNGDCVNTPGSYYCKCHAGFQRTPTKQAC------------------ 573
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDE 722
+ + N + CK+ C GS C C G+ + DG +C D DE
Sbjct: 574 IDIDECIQNGV--------LCKNGR-----CVNTDGSFQCICNAGFELTTDGKNCVDHDE 620
Query: 723 CLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGE 781
C + C+N GSF C+ C G++L + R C D++EC T C G
Sbjct: 621 CT--TTNMCLNGMCINEDGSFKCI-----CKPGFVLAPNGRYCTDVDECQTP-GICMNG- 671
Query: 782 HCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
HC+N+ GSF C C PG A+ M C + G
Sbjct: 672 HCINSEGSFRC----DCPPGLAV-----------GMDGRVCVDTHMRSTCYGGIKKGVCV 716
Query: 842 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 901
R G + E C N EPC+P N+ + +C+ G + DG
Sbjct: 717 RPFPGAVTKSE--CCCANPDYGFGEPCQP-CPAKNSAEFHG------LCSSGVGITVDGR 767
Query: 902 KCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 961
D+NEC C G +C NL GSYRC+C +G++ DA GR CID++EC +
Sbjct: 768 ---DINECALDPDICANG-ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDN 823
Query: 962 HTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC-SQECANIYGSYQCYCRQGYQL 1020
C NT GSY C+C G++ + + CED+NECE+ C + C N GS+ C C G +L
Sbjct: 824 GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKL 883
Query: 1021 AEDGHTCTDI------------------------DECAQGAGILCTFRCLNVPGSYQCAC 1056
+ G C D EC G C AC
Sbjct: 884 SSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERC--ELDTAC 941
Query: 1057 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1104
P G +C+DV+EC + C C N +GSF C ECP
Sbjct: 942 PRG--LARIKGVTCEDVNECEVFPGVCPNGR-CVNSKGSFHC---ECP 983
Score = 189 bits (481), Expect = 1e-47
Identities = 220/799 (27%), Positives = 295/799 (36%), Gaps = 146/799 (18%)
Query: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
AW P P +PQ +P+ D + +IP G+ T E C A
Sbjct: 246 AWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPA 305
Query: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKEGETCGAED 506
G + + +C +I E +C T + C + + C+ G + + +G C +
Sbjct: 306 GHKQSETTQKCEDIDECSIIPGICETGE---CSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
Query: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
C L C L R C CCE + +
Sbjct: 363 TGMCFSGLVN---GRCAQELPGRMTKMQC----------------CCEPGRCWGIGTI-- 401
Query: 567 PPEPAAAPRRVSEA-EMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVG 625
P A P R SE + L +G S PG G G
Sbjct: 402 ---PEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGN----------G 448
Query: 626 SYHCACFPGFSLQDDGRTCRP-EGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
+ + GF G P G Q P + + + TI + N C
Sbjct: 449 NGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITG--LTILNQTIDICKHHANLCL 506
Query: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFY 744
NG C S S C C GY A+G C D DEC ++ C+ CVNT GS+Y
Sbjct: 507 -NGRCIPTVS----SYRCECNMGYKQDANG-DCIDVDECT--SNPCTNGD-CVNTPGSYY 557
Query: 745 CVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL 804
C H A + C+DI+EC+ + C G CVNT GSF C C G+ L
Sbjct: 558 CKCH----AGFQRTPTKQACIDIDECIQNGVLCKNG-RCVNTDGSFQC----ICNAGFEL 608
Query: 805 -KDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINEC 861
DG+ C D DEC T+ C G +C N GSF C C GF+ P G C D++EC
Sbjct: 609 TTDGKNCVDHDECTT-TNMCLNG-MCINEDGSFKC----ICKPGFVLAPNGRYCTDVDEC 662
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV---NECETGVHR--- 915
+ C G CIN+ GS+ C C G DG CVD + C G+ +
Sbjct: 663 QT-PGICMNG-HCINSEGSFRCD-----CPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVC 715
Query: 916 -------------------CGEGQVCHNLPGSYRCD----CKAGFQRDAFGRGCIDVNEC 952
G G+ C P + C +G GR D+NEC
Sbjct: 716 VRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINEC 772
Query: 953 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE---CANIYGS 1009
P CEN GSYRC+C SG+ A G+ C D++EC R + C N GS
Sbjct: 773 ALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGS 832
Query: 1010 YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRS 1069
Y C C GY + TC DI+EC + C N GS+ C C G +++ G
Sbjct: 833 YSCTCPPGYVFRTETETCEDINECESNPCV--NGACRNNLGSFNCEC-SPGSKLSSTGLI 889
Query: 1070 CKD--VDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER---------- 1117
C D C L N ++ NI G+ L+ EC + CER
Sbjct: 890 CIDSLKGTCWL---NIQDSRCEVNINGA--TLKSECCATLGAAWGSPCERCELDTACPRG 944
Query: 1118 ------TTCHDFLECQNSP 1130
TC D EC+ P
Sbjct: 945 LARIKGVTCEDVNECEVFP 963
Score = 187 bits (474), Expect = 7e-47
Identities = 158/532 (29%), Positives = 210/532 (39%), Gaps = 115/532 (21%)
Query: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC--------CVSYLQEKSCMAGVL 494
E C G D C ++ E + C + C C+ C G+
Sbjct: 2276 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI-------CPPGMA 2328
Query: 495 GAKEGETCGAEDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
+GE C D + C GI +C + G CE N G+ +
Sbjct: 2329 RRPDGEGC--VDENECRTKPGICENGRCVNIIG--------SYRCECNE--GFQSSSSGT 2376
Query: 551 SCCEGEEPLIVPEVRRPPEPAAAPRR--VSEAEMAGREALSLGTEAEL------------ 596
C + + L EV + A+ R V+++E G + EL
Sbjct: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
Query: 597 -PN----SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPP 651
P+ + G D DEC ++P CINT+GS+ C C G++ G +C
Sbjct: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC-----ID 2491
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM 711
E Q P PC +C GS CSC GY +
Sbjct: 2492 LDECSQSPK---------------------------PCNYICKNTEGSYQCSCPRGYVLQ 2524
Query: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECV 771
DG +C+D DEC H+C + CVNTLG F C C G+ + H C+D NEC
Sbjct: 2525 EDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTC-----KCPPGFTQH-HTACIDNNECG 2576
Query: 772 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQ 829
+ C C NT GSF C C+ G++L CEDVDEC G H CQ G CQ
Sbjct: 2577 SQPSLCGAKGICQNTPGSFSC----ECQRGFSLDATGLNCEDVDECD-GNHRCQHG--CQ 2629
Query: 830 NTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPG-FSCINTVGSYTCQRNP 887
N G + C C G++Q + N CVD NEC S P G SC NT+GSY C
Sbjct: 2630 NILGGYRC----GCPQGYIQHYQWNQCVDENEC---SNPNACGSASCYNTLGSYKC---- 2678
Query: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 939
C G+ + C DVNEC + + C G C N G Y C C G+ R
Sbjct: 2679 -ACPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYR 2727
Score = 186 bits (472), Expect = 1e-46
Identities = 177/623 (28%), Positives = 239/623 (38%), Gaps = 127/623 (20%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC+ G LC++ C+NT GS+ C C GF L DG+ C
Sbjct: 575 DIDECIQ-NGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCI 633
Query: 663 SEFSQVASNTIPLPLPQPNT--CKDNGPCKQV-------CSTVGGSAICSCFPGYAIMAD 713
+E P + PN C D C+ C GS C C PG A+ D
Sbjct: 634 NEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMD 693
Query: 714 GVSCED---QDECLMGAHD--CSRRQFCVNTLGSFYCVNHTV------------------ 750
G C D + C G C R T C N
Sbjct: 694 GRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
Query: 751 -LCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDG 807
LC+ G + + DINEC D C+ G C N GS+ C C GY
Sbjct: 754 GLCSSGVGITVDGR--DINECALDPDICANGI-CENLRGSYRC----NCNSGYEPDASGR 806
Query: 808 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSE 866
C D+DEC + C G LC+NT GS+ C C G++ E C DINEC S
Sbjct: 807 NCIDIDECLVNRLLCDNG-LCRNTPGSYSCT----CPPGYVFRTETETCEDINECES--N 859
Query: 867 PCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV-----------NECETGVHR 915
PC G +C N +GS+ C+ C+ G S G C+D + CE ++
Sbjct: 860 PCVNG-ACRNNLGSFNCE-----CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING 913
Query: 916 CG-EGQVCHNLPGSY-----RCD----CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 965
+ + C L ++ RC+ C G R G C DVNEC PG C
Sbjct: 914 ATLKSECCATLGAAWGSPCERCELDTACPRGLARIK-GVTCEDVNECEVFPGVCPNGRCV 972
Query: 966 NTLGSYRCSCASGFLLAADGKRCEDV--NECEAQRCSQECAN-----------------I 1006
N+ GS+ C C G L G+ C D+ +C + EC +
Sbjct: 973 NSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAA 1032
Query: 1007 YGS------------YQCYCRQGYQLAEDGHTCT------DIDECAQGAGILCTF-RCLN 1047
+G+ Y+ C +G A G T DI+EC G +CT+ +C N
Sbjct: 1033 WGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG-MCTYGKCRN 1091
Query: 1048 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
GS++C C G+ + R+C D+DEC + C C N GSF C FE +
Sbjct: 1092 TIGSFKCRC-NSGFALDMEERNCTDIDECRISPDLCGSG-ICVNTPGSFECECFEGYESG 1149
Query: 1108 VQVSKTKCERTTCHDFLECQNSP 1130
+ K C D EC+ +P
Sbjct: 1150 FMMMK------NCMDIDECERNP 1166
Score = 99.0 bits (245), Expect = 2e-20
Identities = 103/378 (27%), Positives = 147/378 (38%), Gaps = 55/378 (14%)
Query: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGY----AIMADGVSCEDQDECLMGAHDCSRR 733
P P + P +QV S GS P Y A +A V Q + L G + C R
Sbjct: 33 PPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNVCGSR 92
Query: 734 --QFCVNTLGSFYCVNHTVL------CADGYILNAHRKCVDINECVTDLHTCSRGEHCVN 785
+C + N ++ C DG+ C N C TCS G+ +
Sbjct: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGF-------CSRPNMC-----TCSSGQ-ISS 139
Query: 786 TLGSFHCYK-ALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQN---TKGSFYCQARQ 841
T GS + ++ C G D C+ + +GT+ QP +C+N G R
Sbjct: 140 TCGSKSIQQCSVRCMNGGTCADDHCQ-CQKGYIGTYCGQP--VCENGCQNGGRCIGPNRC 196
Query: 842 RCMDGFLQDPEGNCVDINECTSL--SEPCR---PGFSCINTVGSYT-----------CQR 885
C+ GF C + ++ C+ G C T+ T C
Sbjct: 197 ACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPA 256
Query: 886 NPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRG 945
P C RG+ + C DV+EC+ C +G C N GS+ C C AG ++ +
Sbjct: 257 QPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSETTQK 315
Query: 946 CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCED--VNECEA----QRC 999
C D++EC PG C NT+GSY C C G++ + DG RC D C + RC
Sbjct: 316 CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRC 375
Query: 1000 SQECANIYGSYQCYCRQG 1017
+QE QC C G
Sbjct: 376 AQELPGRMTKMQCCCEPG 393
Score = 94.0 bits (232), Expect = 8e-19
Identities = 91/295 (30%), Positives = 116/295 (39%), Gaps = 60/295 (20%)
Query: 815 CAMGTHT-CQPGFLCQNTKGSFYCQA---RQRCMDGFLQDPEGNCVDINECTSLSEPCRP 870
C H+ C PG+ + G C R C DGF P N CT C
Sbjct: 89 CGSRFHSYCCPGW--KTLPGGNQCIVPICRNSCGDGFCSRP-------NMCT-----CSS 134
Query: 871 GFSCINTVGSYTCQRNPLICARGYHASDDGTKC--------VDVNECETGVHRCGEGQVC 922
G +T GS + Q+ + C G +DD +C CE G C G C
Sbjct: 135 G-QISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG---CQNGGRC 190
Query: 923 HNLPGSYRCDCKAGF-----QRDAFGRGCI-DVNE----------------CWASPGRLC 960
G RC C GF +RD C VN C A+ GR
Sbjct: 191 I---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQG 1017
H CE + C GF+ C+DV+EC+A C C N GS++C C G
Sbjct: 248 GHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
Query: 1018 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
++ +E C DIDEC+ GI T C N GSY C CP +GY + +G C D
Sbjct: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP-RGYVTSTDGSRCID 360
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 282 bits (722), Expect = 1e-75
Identities = 236/740 (31%), Positives = 309/740 (41%), Gaps = 131/740 (17%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 424 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 470
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 471 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 514
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 515 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 559
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 560 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 617
Query: 618 HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPL 677
C N GS+ C C GF G C + E QEP
Sbjct: 618 GACKNLPGSFRCVCPAGFR----GSACEED----VDECAQEPP----------------- 652
Query: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCV 737
C GP + C GS C+C G+ G C+D DEC C+ + C
Sbjct: 653 ----PC---GPGR--CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CE 702
Query: 738 NTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKAL 796
NT GSF CV C G+ N A +C D++EC + H G+ CVN+ GSF C
Sbjct: 703 NTEGSFQCV-----CPMGFQPNTAGSECEDVDEC--ENHLACPGQECVNSPGSFQCR--- 752
Query: 797 TCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-- 854
TC G+ L G C DVDEC+ G C P C NT+GSF C C G+ + P G
Sbjct: 753 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS----CAPGY-RAPSGRPG 807
Query: 855 -CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 913
C D+NEC + C P C+NT GS+ C CA GY G C+DV+EC
Sbjct: 808 PCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPGYRPGPRGASCLDVDECSEE- 860
Query: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC-QHTCENTLGSYR 972
C G +C N GS+ C C G + C+DV+EC LC CEN+ GSYR
Sbjct: 861 DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYR 919
Query: 973 C--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANIYGSYQCY--CRQGYQLAEDG 1024
C C G+ +G C+DV+EC+ + C +Q C N GSY+C C GYQ G
Sbjct: 920 CVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
Query: 1025 HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCS 1084
C D+DEC + C N+PGS+QC C +QGY +GR C DV+EC C
Sbjct: 979 G-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGARDGRHCVDVNECETLQGVCG 1036
Query: 1085 EAETCHNIQGSFRCLRFECP 1104
A C N++GSF C+ CP
Sbjct: 1037 AA-LCENVEGSFLCV---CP 1052
Score = 275 bits (703), Expect = 2e-73
Identities = 217/682 (31%), Positives = 285/682 (41%), Gaps = 101/682 (14%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 358 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 414
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 415 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 471
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 472 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 529
Query: 656 PQEPALKSEFSQVASNTIPLPL----PQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 530 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 588
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK 763
C GY G SC+D DEC C R C N GSF CV C G+ +A +
Sbjct: 589 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCV-----CPAGFRGSACEE 642
Query: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHT 821
D++EC + C G C NT GSFHC C G+ + C+DVDECA
Sbjct: 643 --DVDECAQEPPPCGPGR-CDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPP 695
Query: 822 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGS 880
C G C+NT+GSF C C GF + G+ C D++EC + PG C+N+ GS
Sbjct: 696 CTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 748
Query: 881 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD 940
+ C+ C G+H +C DV+EC +G CG C N GS+RC C G++
Sbjct: 749 FQCRT----CPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 802
Query: 941 AFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 999
+ G C DVNEC C NT GS+ C+CA G+ G C DV+EC +
Sbjct: 803 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 862
Query: 1000 SQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCAC 1056
Q C N GS++C C G++ D +C D+DEC + LC + RC N PGSY+C
Sbjct: 863 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 922
Query: 1057 P-EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1115
+ GY G +C DVDEC A+ C N GS+RC C P Y C
Sbjct: 923 DCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQPTPGGGC 980
Query: 1116 E-------RTTCHDFLECQNSP 1130
+ R+ C CQN P
Sbjct: 981 QDVDECRNRSFCGAHAVCQNLP 1002
Score = 170 bits (431), Expect = 7e-42
Identities = 229/880 (26%), Positives = 302/880 (34%), Gaps = 158/880 (17%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 485
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 486 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 544
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 605 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 662
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 663 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 719 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 778
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF--------- 665
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDFCFPHGECLN 829
Query: 666 --SQVASNTIP--LPLPQPNTCKDNGPCKQ-------VCSTVGGSAICSCFPGYAIMADG 714
A P P P+ +C D C + +C+ GS C C PG+ D
Sbjct: 830 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL 889
Query: 715 VSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDL 774
SC D DEC Q C N+ GS+ CV C GY C D++EC
Sbjct: 890 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRD---CDPGYHAGPEGTCDDVDECQEYG 946
Query: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKG 833
+ C NT GS+ C A C+PGY G C+DVDEC + C +CQN G
Sbjct: 947 PEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPG 1003
Query: 834 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
SF C C G+ +G +CVD+NEC +L C C N GS+ C +C
Sbjct: 1004 SFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CENVEGSFLC-----VCPN 1053
Query: 893 GYHASDDGT-KCVDVNECETGVHRCGEGQVCHN-----------LP-----------GSY 929
D T +CV G + Q + LP GS
Sbjct: 1054 SPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG 1112
Query: 930 RCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQHTCENT-LGSYRCSCAS 977
R +C + + C V E W S R+ Q C T Y+ C
Sbjct: 1113 RRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ--CPGTETAEYQSLCPH 1170
Query: 978 GF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCYCRQGYQLAEDGHTCTDI 1030
G LA G DV+EC+ R C S C N Y CYC GY C D
Sbjct: 1171 GRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1230
Query: 1031 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
DECA RC+N GSY C C E + + R C
Sbjct: 1231 DECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1269
Score = 63.2 bits (152), Expect = 2e-09
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 42/232 (18%)
Query: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
C N L ++ C G G C + +C GT T + LC + +G
Sbjct: 1126 CDNILARNVTWQECCCTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA------ 1176
Query: 843 CMDGFLQDPEGNCV---DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASD 898
P G+ D++EC + C+ G C+NT Y+C C+ GY+
Sbjct: 1177 --------PSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHT 1222
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DV 949
+C+D +EC C EG C N GSY C C+ D R C+ ++
Sbjct: 1223 QRLECIDNDECADEEPAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL 1281
Query: 950 NECWASPGR--LCQHTCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 996
CW G +C H + +Y C C G D C +D ++ EA
Sbjct: 1282 GVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1333
Score = 56.2 bits (134), Expect = 2e-07
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 54/283 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 85 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 140
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
Query: 709 AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDIN 768
++A ED G D S +C L C + L C
Sbjct: 201 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPLPG------LRTQEVCCRGA 248
Query: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECEDVDECAMGTHTCQPGF 826
+H C + C LG+ A C G+ +G CEDVDECA G CQ G
Sbjct: 249 GLAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR-CQHG- 303
Query: 827 LCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 868
C NT+G + C C DGFL D +C+ + + PC
Sbjct: 304 ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 985 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 1035
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
Query: 1036 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
A LC RCLN GS++C C G+ T C
Sbjct: 1516 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1550
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 970
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1532
Query: 971 YRCSCASGF 979
+RC C GF
Sbjct: 1533 FRCICRPGF 1541
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 912 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 964
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 253 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 305
Query: 965 ENTLGSYRCSCASGFLLAADGKRC 988
NT G Y C C GFLL + C
Sbjct: 306 ANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 47.0 bits (110), Expect = 1e-04
Identities = 63/284 (22%), Positives = 95/284 (33%), Gaps = 29/284 (10%)
Query: 489 CMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHV 548
C G GA++G C D + C + CG L EG PN + +
Sbjct: 1009 CDQGYEGARDGRHC--VDVNEC-----ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1061
Query: 549 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS-LGTEAELPNSLP-GDDQD 606
C + P P + P+ + + R L P P G +
Sbjct: 1062 TGRC-------VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRR 1114
Query: 607 ECLL--LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE---PAL 661
EC + C ++ V C C G + G CR + P A + P
Sbjct: 1115 ECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCRIQQCPGTETAEYQSLCPHG 1171
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
+ + ++ + + +D VC C C GY + C D D
Sbjct: 1172 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1231
Query: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCV 765
EC C + CVNT+GS++C L DG + R+CV
Sbjct: 1232 ECADEEPACEGGR-CVNTVGSYHCTCEPPLVLDG----SQRRCV 1270
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1067
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1452 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1502
Query: 1068 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1503 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 1001
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1465 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 1002 --ECANIYGSYQCYCRQGYQLAEDGHTC 1027
C N GS++C CR G+ H C
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 44.7 bits (104), Expect = 6e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 850
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1500
Query: 851 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 903
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1550
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 856 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 912
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1465 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
Query: 913 VHRCGEGQVCHNLPGSYRCDCKAGF 937
C + C N GS+RC C+ GF
Sbjct: 1518 SPLCVNAR-CLNTDGSFRCICRPGF 1541
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 960 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 1012
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 314
Query: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1064
C G+ L +C ++ G C+ L C C G
Sbjct: 315 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 371
Query: 1065 ANGRSCK 1071
A GR C+
Sbjct: 372 AWGRGCQ 378
Score = 41.6 bits (96), Expect = 0.005
Identities = 91/378 (24%), Positives = 115/378 (30%), Gaps = 91/378 (24%)
Query: 454 IDNDECLEIPESGTEDNVCRT-----------------AQRHCCVSYLQEKSCMAGVLGA 496
IDNDEC + E E C +QR C + Q GV
Sbjct: 1228 IDNDECAD-EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
Query: 497 KEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSC-----ESNPNLGYPCNHVMLS 551
+ G + Y +CC G A G C + + + CN
Sbjct: 1287 EVGADLVCSHPRLDRQATYTECCCLYG-----EAWGMDCALCPAQDSDDFEALCN----- 1336
Query: 552 CCEGEEPLIVPEVRRPPEPAA--APRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL 609
++ P PP P P + L G E P +LP D
Sbjct: 1337 -------VLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP- 1388
Query: 610 LLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF-SQV 668
PG + Y F +DDG P G P AP P + + S+
Sbjct: 1389 --PGPFARR-----EAPYGAPRFDMPDFEDDGG---PYGESEAP-APPGPGTRWPYRSRD 1437
Query: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAH 728
+ P P P GGS S Y + + C D C G
Sbjct: 1438 TRRSFPEPEEPPE---------------GGSYAGSLAEPYEEL-EAEECGILDGCTNGR- 1480
Query: 729 DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINEC--VTDLHTCSRGEHCVN 785
CV F C C DGY L+ R CVDINEC C+N
Sbjct: 1481 -------CVRVPEGFTC-----RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1528
Query: 786 TLGSFHCYKALTCEPGYA 803
T GSF C C PG+A
Sbjct: 1529 TDGSFRC----ICRPGFA 1542
Score = 36.2 bits (82), Expect = 0.20
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 1033 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1081
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 244 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 298
Query: 1082 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1115
C E C N +G + C+ CP + + S++ C
Sbjct: 299 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 329
Score = 35.8 bits (81), Expect = 0.26
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 289 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 32.3 bits (72), Expect = 2.9
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1526 CLNTDGSFRCICRPGFAPTHQPHHCAP 1552
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 282 bits (722), Expect = 1e-75
Identities = 236/740 (31%), Positives = 309/740 (41%), Gaps = 131/740 (17%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 454 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 500
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 501 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 544
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 545 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 589
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 590 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 647
Query: 618 HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPL 677
C N GS+ C C GF G C + E QEP
Sbjct: 648 GACKNLPGSFRCVCPAGFR----GSACEED----VDECAQEPP----------------- 682
Query: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCV 737
C GP + C GS C+C G+ G C+D DEC C+ + C
Sbjct: 683 ----PC---GPGR--CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CE 732
Query: 738 NTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKAL 796
NT GSF CV C G+ N A +C D++EC + H G+ CVN+ GSF C
Sbjct: 733 NTEGSFQCV-----CPMGFQPNTAGSECEDVDEC--ENHLACPGQECVNSPGSFQCR--- 782
Query: 797 TCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-- 854
TC G+ L G C DVDEC+ G C P C NT+GSF C C G+ + P G
Sbjct: 783 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS----CAPGY-RAPSGRPG 837
Query: 855 -CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 913
C D+NEC + C P C+NT GS+ C CA GY G C+DV+EC
Sbjct: 838 PCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPGYRPGPRGASCLDVDECSEE- 890
Query: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC-QHTCENTLGSYR 972
C G +C N GS+ C C G + C+DV+EC LC CEN+ GSYR
Sbjct: 891 DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYR 949
Query: 973 C--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANIYGSYQCY--CRQGYQLAEDG 1024
C C G+ +G C+DV+EC+ + C +Q C N GSY+C C GYQ G
Sbjct: 950 CVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1008
Query: 1025 HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCS 1084
C D+DEC + C N+PGS+QC C +QGY +GR C DV+EC C
Sbjct: 1009 G-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGARDGRHCVDVNECETLQGVCG 1066
Query: 1085 EAETCHNIQGSFRCLRFECP 1104
A C N++GSF C+ CP
Sbjct: 1067 AA-LCENVEGSFLCV---CP 1082
Score = 275 bits (703), Expect = 2e-73
Identities = 217/682 (31%), Positives = 285/682 (41%), Gaps = 101/682 (14%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 388 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 444
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 445 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 501
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 502 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 559
Query: 656 PQEPALKSEFSQVASNTIPLPL----PQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 560 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 618
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK 763
C GY G SC+D DEC C R C N GSF CV C G+ +A +
Sbjct: 619 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCV-----CPAGFRGSACEE 672
Query: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHT 821
D++EC + C G C NT GSFHC C G+ + C+DVDECA
Sbjct: 673 --DVDECAQEPPPCGPGR-CDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPP 725
Query: 822 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGS 880
C G C+NT+GSF C C GF + G+ C D++EC + PG C+N+ GS
Sbjct: 726 CTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 778
Query: 881 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD 940
+ C+ C G+H +C DV+EC +G CG C N GS+RC C G++
Sbjct: 779 FQCRT----CPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 832
Query: 941 AFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 999
+ G C DVNEC C NT GS+ C+CA G+ G C DV+EC +
Sbjct: 833 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 892
Query: 1000 SQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCAC 1056
Q C N GS++C C G++ D +C D+DEC + LC + RC N PGSY+C
Sbjct: 893 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 952
Query: 1057 P-EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1115
+ GY G +C DVDEC A+ C N GS+RC C P Y C
Sbjct: 953 DCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQPTPGGGC 1010
Query: 1116 E-------RTTCHDFLECQNSP 1130
+ R+ C CQN P
Sbjct: 1011 QDVDECRNRSFCGAHAVCQNLP 1032
Score = 170 bits (431), Expect = 7e-42
Identities = 229/880 (26%), Positives = 302/880 (34%), Gaps = 158/880 (17%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 460 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 515
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 516 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 574
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 635 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 692
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 693 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 748
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 749 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 808
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF--------- 665
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDFCFPHGECLN 859
Query: 666 --SQVASNTIP--LPLPQPNTCKDNGPCKQ-------VCSTVGGSAICSCFPGYAIMADG 714
A P P P+ +C D C + +C+ GS C C PG+ D
Sbjct: 860 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL 919
Query: 715 VSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDL 774
SC D DEC Q C N+ GS+ CV C GY C D++EC
Sbjct: 920 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRD---CDPGYHAGPEGTCDDVDECQEYG 976
Query: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKG 833
+ C NT GS+ C A C+PGY G C+DVDEC + C +CQN G
Sbjct: 977 PEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPG 1033
Query: 834 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
SF C C G+ +G +CVD+NEC +L C C N GS+ C +C
Sbjct: 1034 SFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CENVEGSFLC-----VCPN 1083
Query: 893 GYHASDDGT-KCVDVNECETGVHRCGEGQVCHN-----------LP-----------GSY 929
D T +CV G + Q + LP GS
Sbjct: 1084 SPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG 1142
Query: 930 RCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQHTCENT-LGSYRCSCAS 977
R +C + + C V E W S R+ Q C T Y+ C
Sbjct: 1143 RRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ--CPGTETAEYQSLCPH 1200
Query: 978 GF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCYCRQGYQLAEDGHTCTDI 1030
G LA G DV+EC+ R C S C N Y CYC GY C D
Sbjct: 1201 GRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1260
Query: 1031 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
DECA RC+N GSY C C E + + R C
Sbjct: 1261 DECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1299
Score = 63.2 bits (152), Expect = 2e-09
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 42/232 (18%)
Query: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
C N L ++ C G G C + +C GT T + LC + +G
Sbjct: 1156 CDNILARNVTWQECCCTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA------ 1206
Query: 843 CMDGFLQDPEGNCV---DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASD 898
P G+ D++EC + C+ G C+NT Y+C C+ GY+
Sbjct: 1207 --------PSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHT 1252
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DV 949
+C+D +EC C EG C N GSY C C+ D R C+ ++
Sbjct: 1253 QRLECIDNDECADEEPAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL 1311
Query: 950 NECWASPGR--LCQHTCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 996
CW G +C H + +Y C C G D C +D ++ EA
Sbjct: 1312 GVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1363
Score = 56.2 bits (134), Expect = 2e-07
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 54/283 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 115 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 170
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 171 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 230
Query: 709 AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDIN 768
++A ED G D S +C L C + L C
Sbjct: 231 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPLPG------LRTQEVCCRGA 278
Query: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECEDVDECAMGTHTCQPGF 826
+H C + C LG+ A C G+ +G CEDVDECA G CQ G
Sbjct: 279 GLAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR-CQHG- 333
Query: 827 LCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 868
C NT+G + C C DGFL D +C+ + + PC
Sbjct: 334 ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 985 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 1035
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1486 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1545
Query: 1036 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
A LC RCLN GS++C C G+ T C
Sbjct: 1546 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1580
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 970
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1506 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1562
Query: 971 YRCSCASGF 979
+RC C GF
Sbjct: 1563 FRCICRPGF 1571
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 912 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 964
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 283 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 335
Query: 965 ENTLGSYRCSCASGFLLAADGKRC 988
NT G Y C C GFLL + C
Sbjct: 336 ANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 47.0 bits (110), Expect = 1e-04
Identities = 63/284 (22%), Positives = 95/284 (33%), Gaps = 29/284 (10%)
Query: 489 CMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHV 548
C G GA++G C D + C + CG L EG PN + +
Sbjct: 1039 CDQGYEGARDGRHC--VDVNEC-----ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1091
Query: 549 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS-LGTEAELPNSLP-GDDQD 606
C + P P + P+ + + R L P P G +
Sbjct: 1092 TGRC-------VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRR 1144
Query: 607 ECLL--LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE---PAL 661
EC + C ++ V C C G + G CR + P A + P
Sbjct: 1145 ECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCRIQQCPGTETAEYQSLCPHG 1201
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
+ + ++ + + +D VC C C GY + C D D
Sbjct: 1202 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1261
Query: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCV 765
EC C + CVNT+GS++C L DG + R+CV
Sbjct: 1262 ECADEEPACEGGR-CVNTVGSYHCTCEPPLVLDG----SQRRCV 1300
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1067
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1482 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1532
Query: 1068 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1533 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1571
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 1001
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1495 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 1002 --ECANIYGSYQCYCRQGYQLAEDGHTC 1027
C N GS++C CR G+ H C
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 44.7 bits (104), Expect = 6e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 850
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1484 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1530
Query: 851 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 903
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1531 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1580
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 856 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 912
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1495 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1547
Query: 913 VHRCGEGQVCHNLPGSYRCDCKAGF 937
C + C N GS+RC C+ GF
Sbjct: 1548 SPLCVNAR-CLNTDGSFRCICRPGF 1571
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 960 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 1012
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 287 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 344
Query: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1064
C G+ L +C ++ G C+ L C C G
Sbjct: 345 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 401
Query: 1065 ANGRSCK 1071
A GR C+
Sbjct: 402 AWGRGCQ 408
Score = 41.6 bits (96), Expect = 0.005
Identities = 91/378 (24%), Positives = 115/378 (30%), Gaps = 91/378 (24%)
Query: 454 IDNDECLEIPESGTEDNVCRT-----------------AQRHCCVSYLQEKSCMAGVLGA 496
IDNDEC + E E C +QR C + Q GV
Sbjct: 1258 IDNDECAD-EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1316
Query: 497 KEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSC-----ESNPNLGYPCNHVMLS 551
+ G + Y +CC G A G C + + + CN
Sbjct: 1317 EVGADLVCSHPRLDRQATYTECCCLYG-----EAWGMDCALCPAQDSDDFEALCN----- 1366
Query: 552 CCEGEEPLIVPEVRRPPEPAA--APRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL 609
++ P PP P P + L G E P +LP D
Sbjct: 1367 -------VLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP- 1418
Query: 610 LLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF-SQV 668
PG + Y F +DDG P G P AP P + + S+
Sbjct: 1419 --PGPFARR-----EAPYGAPRFDMPDFEDDGG---PYGESEAP-APPGPGTRWPYRSRD 1467
Query: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAH 728
+ P P P GGS S Y + + C D C G
Sbjct: 1468 TRRSFPEPEEPPE---------------GGSYAGSLAEPYEEL-EAEECGILDGCTNGR- 1510
Query: 729 DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINEC--VTDLHTCSRGEHCVN 785
CV F C C DGY L+ R CVDINEC C+N
Sbjct: 1511 -------CVRVPEGFTC-----RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1558
Query: 786 TLGSFHCYKALTCEPGYA 803
T GSF C C PG+A
Sbjct: 1559 TDGSFRC----ICRPGFA 1572
Score = 36.2 bits (82), Expect = 0.20
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 1033 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1081
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 274 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 328
Query: 1082 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1115
C E C N +G + C+ CP + + S++ C
Sbjct: 329 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 359
Score = 35.8 bits (81), Expect = 0.26
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 319 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 32.3 bits (72), Expect = 2.9
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1556 CLNTDGSFRCICRPGFAPTHQPHHCAP 1582
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 282 bits (722), Expect = 1e-75
Identities = 236/740 (31%), Positives = 309/740 (41%), Gaps = 131/740 (17%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 491 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 537
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 538 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 581
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 582 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 626
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 627 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 684
Query: 618 HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPL 677
C N GS+ C C GF G C + E QEP
Sbjct: 685 GACKNLPGSFRCVCPAGFR----GSACEED----VDECAQEPP----------------- 719
Query: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCV 737
C GP + C GS C+C G+ G C+D DEC C+ + C
Sbjct: 720 ----PC---GPGR--CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CE 769
Query: 738 NTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKAL 796
NT GSF CV C G+ N A +C D++EC + H G+ CVN+ GSF C
Sbjct: 770 NTEGSFQCV-----CPMGFQPNTAGSECEDVDEC--ENHLACPGQECVNSPGSFQCR--- 819
Query: 797 TCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-- 854
TC G+ L G C DVDEC+ G C P C NT+GSF C C G+ + P G
Sbjct: 820 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS----CAPGY-RAPSGRPG 874
Query: 855 -CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 913
C D+NEC + C P C+NT GS+ C CA GY G C+DV+EC
Sbjct: 875 PCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPGYRPGPRGASCLDVDECSEE- 927
Query: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC-QHTCENTLGSYR 972
C G +C N GS+ C C G + C+DV+EC LC CEN+ GSYR
Sbjct: 928 DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYR 986
Query: 973 C--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANIYGSYQCY--CRQGYQLAEDG 1024
C C G+ +G C+DV+EC+ + C +Q C N GSY+C C GYQ G
Sbjct: 987 CVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1045
Query: 1025 HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCS 1084
C D+DEC + C N+PGS+QC C +QGY +GR C DV+EC C
Sbjct: 1046 G-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGARDGRHCVDVNECETLQGVCG 1103
Query: 1085 EAETCHNIQGSFRCLRFECP 1104
A C N++GSF C+ CP
Sbjct: 1104 AA-LCENVEGSFLCV---CP 1119
Score = 275 bits (703), Expect = 2e-73
Identities = 217/682 (31%), Positives = 285/682 (41%), Gaps = 101/682 (14%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 425 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 481
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 482 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 538
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 539 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 596
Query: 656 PQEPALKSEFSQVASNTIPLPL----PQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 597 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 655
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK 763
C GY G SC+D DEC C R C N GSF CV C G+ +A +
Sbjct: 656 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCV-----CPAGFRGSACEE 709
Query: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHT 821
D++EC + C G C NT GSFHC C G+ + C+DVDECA
Sbjct: 710 --DVDECAQEPPPCGPGR-CDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPP 762
Query: 822 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGS 880
C G C+NT+GSF C C GF + G+ C D++EC + PG C+N+ GS
Sbjct: 763 CTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 815
Query: 881 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD 940
+ C+ C G+H +C DV+EC +G CG C N GS+RC C G++
Sbjct: 816 FQCRT----CPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 869
Query: 941 AFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 999
+ G C DVNEC C NT GS+ C+CA G+ G C DV+EC +
Sbjct: 870 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 929
Query: 1000 SQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCAC 1056
Q C N GS++C C G++ D +C D+DEC + LC + RC N PGSY+C
Sbjct: 930 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 989
Query: 1057 P-EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1115
+ GY G +C DVDEC A+ C N GS+RC C P Y C
Sbjct: 990 DCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQPTPGGGC 1047
Query: 1116 E-------RTTCHDFLECQNSP 1130
+ R+ C CQN P
Sbjct: 1048 QDVDECRNRSFCGAHAVCQNLP 1069
Score = 170 bits (431), Expect = 7e-42
Identities = 229/880 (26%), Positives = 302/880 (34%), Gaps = 158/880 (17%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 497 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 552
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 553 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 611
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 672 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 729
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 730 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 785
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 786 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 845
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF--------- 665
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDFCFPHGECLN 896
Query: 666 --SQVASNTIP--LPLPQPNTCKDNGPCKQ-------VCSTVGGSAICSCFPGYAIMADG 714
A P P P+ +C D C + +C+ GS C C PG+ D
Sbjct: 897 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL 956
Query: 715 VSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDL 774
SC D DEC Q C N+ GS+ CV C GY C D++EC
Sbjct: 957 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRD---CDPGYHAGPEGTCDDVDECQEYG 1013
Query: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKG 833
+ C NT GS+ C A C+PGY G C+DVDEC + C +CQN G
Sbjct: 1014 PEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPG 1070
Query: 834 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
SF C C G+ +G +CVD+NEC +L C C N GS+ C +C
Sbjct: 1071 SFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CENVEGSFLC-----VCPN 1120
Query: 893 GYHASDDGT-KCVDVNECETGVHRCGEGQVCHN-----------LP-----------GSY 929
D T +CV G + Q + LP GS
Sbjct: 1121 SPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG 1179
Query: 930 RCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQHTCENT-LGSYRCSCAS 977
R +C + + C V E W S R+ Q C T Y+ C
Sbjct: 1180 RRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ--CPGTETAEYQSLCPH 1237
Query: 978 GF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCYCRQGYQLAEDGHTCTDI 1030
G LA G DV+EC+ R C S C N Y CYC GY C D
Sbjct: 1238 GRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDN 1297
Query: 1031 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
DECA RC+N GSY C C E + + R C
Sbjct: 1298 DECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1336
Score = 63.2 bits (152), Expect = 2e-09
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 42/232 (18%)
Query: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
C N L ++ C G G C + +C GT T + LC + +G
Sbjct: 1193 CDNILARNVTWQECCCTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA------ 1243
Query: 843 CMDGFLQDPEGNCV---DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASD 898
P G+ D++EC + C+ G C+NT Y+C C+ GY+
Sbjct: 1244 --------PSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHT 1289
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DV 949
+C+D +EC C EG C N GSY C C+ D R C+ ++
Sbjct: 1290 QRLECIDNDECADEEPAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL 1348
Query: 950 NECWASPGR--LCQHTCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 996
CW G +C H + +Y C C G D C +D ++ EA
Sbjct: 1349 GVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1400
Score = 56.2 bits (134), Expect = 2e-07
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 54/283 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 152 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 207
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 208 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 267
Query: 709 AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDIN 768
++A ED G D S +C L C + L C
Sbjct: 268 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPLPG------LRTQEVCCRGA 315
Query: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECEDVDECAMGTHTCQPGF 826
+H C + C LG+ A C G+ +G CEDVDECA G CQ G
Sbjct: 316 GLAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR-CQHG- 370
Query: 827 LCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 868
C NT+G + C C DGFL D +C+ + + PC
Sbjct: 371 ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 985 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 1035
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1523 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1582
Query: 1036 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
A LC RCLN GS++C C G+ T C
Sbjct: 1583 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1617
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 970
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1599
Query: 971 YRCSCASGF 979
+RC C GF
Sbjct: 1600 FRCICRPGF 1608
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 912 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 964
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 320 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 372
Query: 965 ENTLGSYRCSCASGFLLAADGKRC 988
NT G Y C C GFLL + C
Sbjct: 373 ANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 47.0 bits (110), Expect = 1e-04
Identities = 63/284 (22%), Positives = 95/284 (33%), Gaps = 29/284 (10%)
Query: 489 CMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHV 548
C G GA++G C D + C + CG L EG PN + +
Sbjct: 1076 CDQGYEGARDGRHC--VDVNEC-----ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1128
Query: 549 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS-LGTEAELPNSLP-GDDQD 606
C + P P + P+ + + R L P P G +
Sbjct: 1129 TGRC-------VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRR 1181
Query: 607 ECLL--LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE---PAL 661
EC + C ++ V C C G + G CR + P A + P
Sbjct: 1182 ECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCRIQQCPGTETAEYQSLCPHG 1238
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
+ + ++ + + +D VC C C GY + C D D
Sbjct: 1239 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1298
Query: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCV 765
EC C + CVNT+GS++C L DG + R+CV
Sbjct: 1299 ECADEEPACEGGR-CVNTVGSYHCTCEPPLVLDG----SQRRCV 1337
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1067
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1519 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1569
Query: 1068 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1570 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1608
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 1001
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1532 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 1002 --ECANIYGSYQCYCRQGYQLAEDGHTC 1027
C N GS++C CR G+ H C
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 44.7 bits (104), Expect = 6e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 850
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1521 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1567
Query: 851 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 903
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1568 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1617
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 856 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 912
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1532 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1584
Query: 913 VHRCGEGQVCHNLPGSYRCDCKAGF 937
C + C N GS+RC C+ GF
Sbjct: 1585 SPLCVNAR-CLNTDGSFRCICRPGF 1608
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 960 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 1012
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 324 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 381
Query: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1064
C G+ L +C ++ G C+ L C C G
Sbjct: 382 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 438
Query: 1065 ANGRSCK 1071
A GR C+
Sbjct: 439 AWGRGCQ 445
Score = 41.6 bits (96), Expect = 0.005
Identities = 91/378 (24%), Positives = 115/378 (30%), Gaps = 91/378 (24%)
Query: 454 IDNDECLEIPESGTEDNVCRT-----------------AQRHCCVSYLQEKSCMAGVLGA 496
IDNDEC + E E C +QR C + Q GV
Sbjct: 1295 IDNDECAD-EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1353
Query: 497 KEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSC-----ESNPNLGYPCNHVMLS 551
+ G + Y +CC G A G C + + + CN
Sbjct: 1354 EVGADLVCSHPRLDRQATYTECCCLYG-----EAWGMDCALCPAQDSDDFEALCN----- 1403
Query: 552 CCEGEEPLIVPEVRRPPEPAA--APRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL 609
++ P PP P P + L G E P +LP D
Sbjct: 1404 -------VLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP- 1455
Query: 610 LLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF-SQV 668
PG + Y F +DDG P G P AP P + + S+
Sbjct: 1456 --PGPFARR-----EAPYGAPRFDMPDFEDDGG---PYGESEAP-APPGPGTRWPYRSRD 1504
Query: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAH 728
+ P P P GGS S Y + + C D C G
Sbjct: 1505 TRRSFPEPEEPPE---------------GGSYAGSLAEPYEEL-EAEECGILDGCTNGR- 1547
Query: 729 DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINEC--VTDLHTCSRGEHCVN 785
CV F C C DGY L+ R CVDINEC C+N
Sbjct: 1548 -------CVRVPEGFTC-----RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1595
Query: 786 TLGSFHCYKALTCEPGYA 803
T GSF C C PG+A
Sbjct: 1596 TDGSFRC----ICRPGFA 1609
Score = 36.2 bits (82), Expect = 0.20
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 1033 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1081
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 311 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 365
Query: 1082 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1115
C E C N +G + C+ CP + + S++ C
Sbjct: 366 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 396
Score = 35.8 bits (81), Expect = 0.26
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 356 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 32.3 bits (72), Expect = 2.9
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1593 CLNTDGSFRCICRPGFAPTHQPHHCAP 1619
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 278 bits (710), Expect = 3e-74
Identities = 179/550 (32%), Positives = 260/550 (47%), Gaps = 82/550 (14%)
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-R 762
C G+ + + G C D+DEC G + CS C N +G++YC C G + A R
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS--CHNAMGTYYCS-----CPKGLTIAADGR 5143
Query: 763 KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDG-ECEDVDECAMGTH 820
C DI+EC HTC G+ C NT+GS+ C + C G+ DG C+D++EC +
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRC--VVRCGSGFRRTSDGLSCQDINECQESSP 5201
Query: 821 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGS 880
Q C N GSF+C C G+ Q C+D+NEC CRP C NT G
Sbjct: 5202 CHQR---CFNAIGSFHCG----CEPGY-QLKGRKCMDVNECRQ--NVCRPDQHCKNTRGG 5251
Query: 881 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD 940
Y C +C G +++GT C+D++EC+ G H+C Q+C N GSYRC C G++
Sbjct: 5252 YKCID---LCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQ 5307
Query: 941 AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDV--------- 991
GR C+D+NEC P + C H C NT GS++C C G L DGK C +
Sbjct: 5308 GVGRPCMDINECEQVP-KPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQ 5366
Query: 992 -------------NECEAQRCSQECANIYGSYQCY-----------------CRQGYQLA 1021
N + Q+ ++ +++Y SY Y C +G + +
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEAS 5426
Query: 1022 EDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTH 1081
D TC DIDEC C C N GSYQC CP GY +T NG++C+D+DEC
Sbjct: 5427 HD--TCVDIDECENTDA--CQHECKNTFGSYQCICP-PGYQLTHNGKTCQDIDECLEQNV 5481
Query: 1082 NCSEAETCHNIQGSFRCLRFECPPNYVQVSKTK-CERTTCHDFLECQNSPARITHYQLNF 1140
+C C N++GS++C+ CPPNY + + C + + LEC SP + + ++
Sbjct: 5482 HCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSL 5541
Query: 1141 QTGLLVPAHIFRIGPAPAFTGDTI-----ALNIIKGNEEGYFGTRRLNAYTGVVYLQRAV 1195
G+ + R+ A+T D + ++ + F R N GVVY R +
Sbjct: 5542 PFGIATNQDLIRL---VAYTQDGVMHPRTTFLMVDEEQTVPFALRDEN-LKGVVYTTRPL 5597
Query: 1196 LEPRDFALDV 1205
E + + V
Sbjct: 5598 REAETYRMRV 5607
Score = 154 bits (388), Expect = 7e-37
Identities = 125/425 (29%), Positives = 167/425 (39%), Gaps = 88/425 (20%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-- 661
D+DEC G C H C N +G+Y+C+C G ++ DGRTC+ E AL
Sbjct: 5107 DEDECAA--GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDI---------DECALGR 5155
Query: 662 -KSEFSQVASNTIP------------------LPLPQPNTCKDNGPCKQVCSTVGGSAIC 702
Q NTI L N C+++ PC Q C GS C
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215
Query: 703 SCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR 762
C PGY + G C D +EC C Q C NT G + C++ LC +G +
Sbjct: 5216 GCEPGYQL--KGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCID---LCPNGMTKAENG 5268
Query: 763 KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK--DGECEDVDECAMGTH 820
C+DI+EC H C + C NT GS+ C C GY + C D++EC
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRC----VCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 821 TCQPGFLCQNTKGSF---------------YCQARQRCMDGFLQDPEGNCVDINECTSLS 865
C C NT GSF C +R + Q N + +
Sbjct: 5325 PC--AHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNY 5382
Query: 866 EPCRPGFSCINTVGSYTCQRNP------------LICARGYHASDDGTKCVDVNECETGV 913
+P + + SY+ RN C G AS D CVD++ECE
Sbjct: 5383 QPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECE-NT 5439
Query: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC-----WASPGRLCQHTCENTL 968
C C N GSY+C C G+Q G+ C D++EC P R+ C N
Sbjct: 5440 DAC--QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM----CFNMR 5493
Query: 969 GSYRC 973
GSY+C
Sbjct: 5494 GSYQC 5498
Score = 97.4 bits (241), Expect = 7e-20
Identities = 123/492 (25%), Positives = 173/492 (35%), Gaps = 136/492 (27%)
Query: 434 PEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV 493
P G T D + CA D DEC N C + + +Y SC G+
Sbjct: 5093 PSGFTLDSVGPFCA-------DEDEC-------AAGNPCSHSCHNAMGTYYC--SCPKGL 5136
Query: 494 LGAKEGETCGAEDNDSCGISLYK----QCCD-------C---CGLGLRVRAEGQSCE--S 537
A +G TC +D D C + + Q CD C CG G R ++G SC+ +
Sbjct: 5137 TIAADGRTC--QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDIN 5194
Query: 538 NPNLGYPCNHVMLSC-------CE------GEEPLIVPEVRRPPEPAAAPRRVSEAEMAG 584
PC+ + CE G + + V E R + P + + G
Sbjct: 5195 ECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECR---QNVCRPDQHCKNTRGG 5251
Query: 585 REALSLGTEAELPNSLPGDDQDECLLLP-----GELCQH--LCINTVGSYHCACFPGFSL 637
+ + L PN + + C+ + C++ +C NT GSY C C G+
Sbjct: 5252 YKCIDL-----CPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS 5306
Query: 638 QDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVG 697
Q GR C E Q P PC CS
Sbjct: 5307 QGVGRPCMDIN-----ECEQVPK---------------------------PCAHQCSNTP 5334
Query: 698 GSAICSCFPGYAIMADGVSC----------------------------EDQDECLMGAHD 729
GS C C PG ++ DG SC + Q +H
Sbjct: 5335 GSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHL 5394
Query: 730 CSRRQFCVNTLGSFYCVNHTV--LCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTL 787
S N+ S T+ C +G +H CVDI+EC +T + C NT
Sbjct: 5395 YSSYSEYRNSRTSLSRTRRTIRKTCPEGSEA-SHDTCVDIDECE---NTDACQHECKNTF 5450
Query: 788 GSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
GS+ C C PGY L C+D+DEC C P +C N +GS+ C C
Sbjct: 5451 GSYQC----ICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC-IDTPCPP 5505
Query: 846 GFLQDP-EGNCV 856
+ +DP G C+
Sbjct: 5506 NYQRDPVSGFCL 5517
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 277 bits (709), Expect = 4e-74
Identities = 195/525 (37%), Positives = 253/525 (48%), Gaps = 73/525 (13%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +ECL P + + CIN VGSY C C+PG++L G T
Sbjct: 887 DDNECLRDPCK-GKGRCINRVGSYSCFCYPGYTLATSGAT-------------------Q 926
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCK-QVCSTVGGSAICSCFPGYAIMADGVSCEDQDE 722
E + N C+ G C C+ GS C C GY ++ G C+D +E
Sbjct: 927 ECQDI------------NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINE 973
Query: 723 CLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEH 782
C R CVN+ GS+ C + C +GY CVD+NEC+T C+ G+
Sbjct: 974 CRHPGTCPDGR--CVNSPGSYTC----LACEEGY-RGQSGSCVDVNECLTP-GVCAHGK- 1024
Query: 783 CVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 840
C N GSF C +CE GY + E C+DVDECA +C G LC NT+GSF C A
Sbjct: 1025 CTNLEGSFRC----SCEQGYEVTSDEKGCQDVDECA-SRASCPTG-LCLNTEGSFACSA- 1077
Query: 841 QRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 899
C +G+ + +G C D++EC + C P C NT GS++C+ C GY S
Sbjct: 1078 --CENGYWVNEDGTACEDLDEC-AFPGVC-PSGVCTNTAGSFSCKD----CDGGYRPSPL 1129
Query: 900 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 959
G C DV+ECE C G+ C N GSY+C C GFQ A G C DVNEC
Sbjct: 1130 GDSCEDVDECEDPQSSCLGGE-CKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCA 1187
Query: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQG 1017
C N+ GS+ C CA GF+ A G C+DV+EC C N GS+ C C G
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETG 1247
Query: 1018 YQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCACP-EQGYTMTANGRSCKDVDE 1075
+Q + + C DIDEC +C T++C N PGSY+C + G+ M NG C D+DE
Sbjct: 1248 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDE 1306
Query: 1076 CALGTHNCSEAETCHNIQGSFRCL---RFECPPN-YVQVSKTKCE 1116
CA T C C N GSFRCL FE P+ + V +CE
Sbjct: 1307 CANDT-MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECE 1350
Score = 250 bits (638), Expect = 7e-66
Identities = 210/683 (30%), Positives = 281/683 (41%), Gaps = 136/683 (19%)
Query: 516 KQCCDCCGLGLRVRAEGQSCESNPNLG---------------YPCNHVMLSCCEGEEPLI 560
KQ C C +G +A G CE P G Y + + LS + EE
Sbjct: 693 KQICCCSRVG---KAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEE-- 747
Query: 561 VPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLC 620
E+ RPP + A R+ L + T+ L D D G++
Sbjct: 748 --ELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDS---QAGQV----- 797
Query: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNT---IPLPL 677
T H + G+ P P++ + + QV +T + L
Sbjct: 798 --TTSVTHAPAWV-------------TGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLST 842
Query: 678 PQPNTCKDN-----GPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSR 732
P + C GP C + C C PGY + C D +ECL C
Sbjct: 843 PGIDRCAAGATNVCGP--GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDPCKG 898
Query: 733 RQFCVNTLGSFYCVNHTVLCADGYIL---NAHRKCVDINECVTDLHTCSRGEHCVNTLGS 789
+ C+N +GS+ C C GY L A ++C DINEC CS G+ C NT GS
Sbjct: 899 KGRCINRVGSYSC-----FCYPGYTLATSGATQECQDINEC-EQPGVCSGGQ-CTNTEGS 951
Query: 790 FHC-------------------------------------YKALTCEPGYALKDGECEDV 812
+HC Y L CE GY + G C DV
Sbjct: 952 YHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDV 1011
Query: 813 DECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPG 871
+EC + C G C N +GSF C C G+ + E C D++EC S + C G
Sbjct: 1012 NEC-LTPGVCAHG-KCTNLEGSFRCS----CEQGYEVTSDEKGCQDVDECASRAS-CPTG 1064
Query: 872 FSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECE-TGVHRCGEGQVCHNLPGSYR 930
C+NT GS+ C C GY ++DGT C D++EC GV C G VC N GS+
Sbjct: 1065 L-CLNTEGSFACS----ACENGYWVNEDGTACEDLDECAFPGV--CPSG-VCTNTAGSFS 1116
Query: 931 C-DCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCE 989
C DC G++ G C DV+EC C+NT+GSY+C C GF L A+G CE
Sbjct: 1117 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCE 1175
Query: 990 DVNECEA-QRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCL 1046
DVNEC + C+ EC N +GS+ C C G+ AE G +C D+DECA C+
Sbjct: 1176 DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVGGHCV 1234
Query: 1047 NVPGSYQCACPEQGYTMTANGRSCKDVDECA-LGTHNCSEAETCHNIQGSFRCLRFECPP 1105
N GS+ C C E G+ + C D+DEC G C + C N GS+RC+ C P
Sbjct: 1235 NTEGSFNCLC-ETGFQPSPESGECVDIDECEDYGDPVCGTWK-CENSPGSYRCV-LGCQP 1291
Query: 1106 NYVQVSKTKCERTTCHDFLECQN 1128
+ C D EC N
Sbjct: 1292 GF-----HMAPNGDCIDIDECAN 1309
Score = 238 bits (607), Expect = 3e-62
Identities = 172/506 (33%), Positives = 228/506 (45%), Gaps = 55/506 (10%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT-----CRPEGHPPQPEAPQE 658
D +EC PG C NT GSYHC C G+ + G CR G P
Sbjct: 930 DINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNS 988
Query: 659 P------ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIM 711
P A + + + + + + N C G C C+ + GS CSC GY +
Sbjct: 989 PGSYTCLACEEGYRGQSGSCVDV-----NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVT 1043
Query: 712 ADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINEC 770
+D C+D DEC A C C+NT GSF C C +GY +N C D++EC
Sbjct: 1044 SDEKGCQDVDECASRA-SCPTG-LCLNTEGSFACS----ACENGYWVNEDGTACEDLDEC 1097
Query: 771 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLC 828
C G C NT GSF C C+ GY CEDVDEC +C G C
Sbjct: 1098 AFP-GVCPSGV-CTNTAGSFSCKD---CDGGYRPSPLGDSCEDVDECEDPQSSCLGGE-C 1151
Query: 829 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 888
+NT GS+ C C GF C D+NEC E C P C+N+ GS+ C
Sbjct: 1152 KNTVGSYQCL----CPQGFQLANGTVCEDVNECMG-EEHCAPHGECLNSHGSFFC----- 1201
Query: 889 ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 948
+CA G+ +++ GT C DV+EC T C G C N GS+ C C+ GFQ C+D
Sbjct: 1202 LCAPGFVSAEGGTSCQDVDECAT-TDPCVGGH-CVNTEGSFNCLCETGFQPSPESGECVD 1259
Query: 949 VNECWASPGRLC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEAQR-CSQE-- 1002
++EC +C CEN+ GSYRC C GF +A +G C D++EC C
Sbjct: 1260 IDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGF 1318
Query: 1003 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1062
C N GS++C C QG++++ G C D++EC + C NV GS+ C C
Sbjct: 1319 CDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE 1378
Query: 1063 MTANGRSCKDVDECALGTHNCSEAET 1088
A C+ G + SEA T
Sbjct: 1379 YDAQEGHCR---PRGAGGQSMSEAPT 1401
Score = 177 bits (450), Expect = 4e-44
Identities = 249/972 (25%), Positives = 342/972 (35%), Gaps = 236/972 (24%)
Query: 277 SEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARP 336
+EEEE RE+ G R LP A P + + EAG + G
Sbjct: 744 AEEEELARPPREQ----------GQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKG--- 790
Query: 337 EENLILDAQATSRSTGPEGVTHAPS--LGKAAL--VPTQAVPGSPRDPVKPSPHNILSTS 392
D+QA +T VTHAP+ G A +P Q + + V PS +++ S
Sbjct: 791 ------DSQAGQVTTS---VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLS 841
Query: 393 LPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQ- 451
P + P + ++P D C+ G Q
Sbjct: 842 TPGIDRCA--------------AGATNVCGPGTCVNLP---------DGYRCVCSPGYQL 878
Query: 452 -----WAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAED 506
+ D++ECL P G + R C C G A G T +D
Sbjct: 879 HPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCF--------CYPGYTLATSGATQECQD 930
Query: 507 NDSC---GISLYKQC--------CDCCGLGLRVRA----------EGQSCESNPNLGYPC 545
+ C G+ QC C+C + VR +C + P
Sbjct: 931 INECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPG 990
Query: 546 NHVMLSCCEGEEP-----LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
++ L+C EG + V E P A + + E + R + G E +
Sbjct: 991 SYTCLACEEGYRGQSGSCVDVNECLTPG--VCAHGKCTNLEGSFRCSCEQGYEVT-SDEK 1047
Query: 601 PGDDQDECLLLPGELCQHLCINTVGSYHC-ACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
D DEC LC+NT GS+ C AC G+ + +DG C P
Sbjct: 1048 GCQDVDECASR-ASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSG 1106
Query: 660 ALKS---EFSQVASNTIPLPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGY 708
+ FS + P P ++C+D C+ C GS C C G+
Sbjct: 1107 VCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGF 1166
Query: 709 AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYI-LNAHRKCVDI 767
+ A+G CED +EC MG C+ C+N+ GSF+C LCA G++ C D+
Sbjct: 1167 QL-ANGTVCEDVNEC-MGEEHCAPHGECLNSHGSFFC-----LCAPGFVSAEGGTSCQDV 1219
Query: 768 NECVTDLHTCSRGEHCVNTLGSFHC----------------------------------- 792
+EC T C G HCVNT GSF+C
Sbjct: 1220 DECATT-DPCVGG-HCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCE 1277
Query: 793 -----YKA-LTCEPGYALK-DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
Y+ L C+PG+ + +G+C D+DECA T GF C NT GSF C C
Sbjct: 1278 NSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGF-CDNTDGSFRCL----CDQ 1332
Query: 846 GFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY--------HA 896
GF P G +CVD+NEC + C C N GS+ C +CA H
Sbjct: 1333 GFEISPSGWDCVDVNECELMLAVCGAAL-CENVEGSFLC-----LCASDLEEYDAQEGHC 1386
Query: 897 SDDGTKCVDVNECETGVHR-------CGEGQVCHNLPGSY--------RCDCKAGFQ-RD 940
G ++E TG H C GQ H S C C G D
Sbjct: 1387 RPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGD 1446
Query: 941 AF-----------------GRGCIDVNECWA---------------SPGRLCQHTCENTL 968
A G+G I V W PG C NT+
Sbjct: 1447 ACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTV 1506
Query: 969 GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTC 1027
Y C C GF A K+CED +EC+ C EC N GS+ C+C L C
Sbjct: 1507 PGYVCLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSPPLTLDLSQQRC 1566
Query: 1028 ---TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD----ECALGT 1080
T E I C + C+ P +G+ T C+D + +CAL
Sbjct: 1567 MNSTSSTEDLPDHDIHMDI-CWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Query: 1081 HNCSE--AETCH 1090
SE A+ C+
Sbjct: 1626 PRSSEVYAQLCN 1637
Score = 145 bits (366), Expect = 2e-34
Identities = 95/239 (39%), Positives = 118/239 (49%), Gaps = 20/239 (8%)
Query: 906 VNECETGVHR-CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 964
++ C G CG G C NLP YRC C G+Q C D NEC P + + C
Sbjct: 845 IDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCK-GKGRC 902
Query: 965 ENTLGSYRCSCASGFLLAADG--KRCEDVNECEAQR-CS-QECANIYGSYQCYCRQGYQL 1020
N +GSY C C G+ LA G + C+D+NECE CS +C N GSY C C QGY +
Sbjct: 903 INRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIM 962
Query: 1021 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
GH C DI+EC + G RC+N PGSY C E+GY SC DV+EC L
Sbjct: 963 VRKGH-CQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNEC-LTP 1017
Query: 1081 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLN 1139
C+ + C N++GSFRC C Y S K C D EC + + T LN
Sbjct: 1018 GVCAHGK-CTNLEGSFRC---SCEQGYEVTSDEK----GCQDVDECASRASCPTGLCLN 1068
Score = 89.7 bits (221), Expect = 2e-17
Identities = 157/622 (25%), Positives = 228/622 (36%), Gaps = 109/622 (17%)
Query: 437 STKDLIETCCAAGQQWAIDNDECLEIPE-SGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVL 494
+T+ C G Q + ++ EC++I E D VC T + + SY C G
Sbjct: 1235 NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 495 GAKEGETCGAED--NDS-CGISLYKQCCD-----CCGLGLRVRAEGQSCESNPNLGYPCN 546
A G+ ++ ND+ CG + D C G + G C C
Sbjct: 1295 MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNE----CE 1350
Query: 547 HVMLSC----CEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPG 602
++ C CE E + E A AG +++S EA + P
Sbjct: 1351 LMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMS---EAPTGDHAPA 1407
Query: 603 DDQDECLLLPGELCQHLCINTVG----SYHCACFPGFSLQDDGRTCRPEGHPPQPEA--- 655
+ +C G+ C + +G C C G S D C E E
Sbjct: 1408 PTRMDCY--SGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPS 1465
Query: 656 -----PQEPALKSEFSQVA-SNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYA 709
P E A F Q ++ + P C NG C +TV G +C C PG+
Sbjct: 1466 GKGYIPVEGAWT--FGQTMYTDADECVIFGPGLCP-NGRC---LNTVPGY-VCLCNPGFH 1518
Query: 710 IMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINE 769
A CED DEC A C + CVNT GSF+C L D + ++C++
Sbjct: 1519 YDASHKKCEDHDECQDLA--CENGE-CVNTEGSFHCFCSPPLTLD----LSQQRCMNSTS 1571
Query: 770 CVTDLHTCSRGEHCVNTLGSFHCYKALT----CEP--GYALKDGEC--EDVDECAMGTHT 821
DL +H ++ C+K +T EP G+ EC +D + +
Sbjct: 1572 STEDLP-----DHDIHM---DICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCAL 1623
Query: 822 CQP------GFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVD--------------INEC 861
C P LC + +A G+ P + + +
Sbjct: 1624 CPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPE 1683
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLI--------CARGYHASDD----GTKCVDVNEC 909
++ EP P NT G ++ R P++ Y AS G + + EC
Sbjct: 1684 DTVPEPAFP-----NTAG-HSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEEC 1737
Query: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC--WASPGRLCQH-TCEN 966
++ C G+ C + Y CDC GFQ DA C+DVNEC P LC H CEN
Sbjct: 1738 GI-LNGCENGR-CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCEN 1795
Query: 967 TLGSYRCSCASGFLLAADGKRC 988
T GSYRC C+ G++ A C
Sbjct: 1796 TEGSYRCHCSPGYVAEAGPPHC 1817
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 986 KRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQGAGILCTF 1043
+ C +N CE RC + Y C C +G+QL C D++EC G +LC
Sbjct: 1735 EECGILNGCENGRC----VRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 1044 -RCLNVPGSYQCACPEQGYTMTANGRSC 1070
C N GSY+C C GY A C
Sbjct: 1791 GYCENTEGSYRCHC-SPGYVAEAGPPHC 1817
Score = 48.5 bits (114), Expect = 4e-05
Identities = 32/85 (37%), Positives = 39/85 (45%), Gaps = 10/85 (11%)
Query: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE-----AQRCS 1000
+ EC G C++ C Y C C GF L A C DVNEC+ A C
Sbjct: 1732 LQAEECGILNG--CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCV 1789
Query: 1001 QE-CANIYGSYQCYCRQGYQLAEDG 1024
C N GSY+C+C GY +AE G
Sbjct: 1790 HGYCENTEGSYRCHCSPGY-VAEAG 1813
Score = 43.5 bits (101), Expect = 0.001
Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 43/184 (23%)
Query: 633 PGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI----PLPLPQPNTCKDNGP 688
PG SL D G PP+P P P + + NT+ PL + T +D
Sbjct: 519 PGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQED--- 575
Query: 689 CKQVCSTVGG------SAICSCFPGYAIMADG-------------VSCEDQDECL-MGAH 728
C +VG A C P ++ +G C+D +ECL +G
Sbjct: 576 ---CCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGL- 631
Query: 729 DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLG 788
C + CVNT GS+ C C G +L+ R + CV+D C +LG
Sbjct: 632 -CKDAE-CVNTRGSYLCT-----CRPGLMLDPSR-----SRCVSDKAISMLQGLCYRSLG 679
Query: 789 SFHC 792
C
Sbjct: 680 PGTC 683
Score = 41.6 bits (96), Expect = 0.005
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 14/139 (10%)
Query: 863 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVC 922
+L PC P S + L C +GY + T C D+NEC T + C + + C
Sbjct: 587 TLCAPCPP------RPASPVIENGQLECPQGYKRLNL-THCQDINECLT-LGLCKDAE-C 637
Query: 923 HNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLA 982
N GSY C C+ G D C+ + Q C +LG C+ +
Sbjct: 638 VNTRGSYLCTCRPGLMLDPSRSRCVSDKAI-----SMLQGLCYRSLGPGTCTLPLAQRIT 692
Query: 983 ADGKRCEDVNECEAQRCSQ 1001
C V + C +
Sbjct: 693 KQICCCSRVGKAWGSECEK 711
Score = 41.6 bits (96), Expect = 0.005
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 1027 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC--ALGTHNCS 1084
C ++ C G RC+ V Y C C E G+ + A +C DV+EC G
Sbjct: 1737 CGILNGCENG-------RCVRVREGYTCDCFE-GFQLDAAHMACVDVNECDDLNGPAVLC 1788
Query: 1085 EAETCHNIQGSFRCLRFECPPNYV 1108
C N +GS+RC C P YV
Sbjct: 1789 VHGYCENTEGSYRC---HCSPGYV 1809
Score = 36.6 bits (83), Expect = 0.15
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 7/72 (9%)
Query: 988 CEDVNECEAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 1045
C+D+NEC + EC N GSY C CR G L C + G+ C
Sbjct: 620 CQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGL-----C 674
Query: 1046 LNVPGSYQCACP 1057
G C P
Sbjct: 675 YRSLGPGTCTLP 686
Score = 35.0 bits (79), Expect = 0.44
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 604 DQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTC 644
D +ECL L LC+ C+NT GSY C C PG L C
Sbjct: 622 DINECLTLG--LCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 34.7 bits (78), Expect = 0.58
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 14/67 (20%)
Query: 845 DGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
+G L+ P+G +C DINEC +L C+ C+NT GSY C C G
Sbjct: 603 NGQLECPQGYKRLNLTHCQDINECLTLG-LCKDA-ECVNTRGSYLC-----TCRPGLMLD 655
Query: 898 DDGTKCV 904
++CV
Sbjct: 656 PSRSRCV 662
Score = 34.3 bits (77), Expect = 0.75
Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 14/90 (15%)
Query: 796 LTCEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP-EG 853
L C GY L C+D++EC + C+ C NT+GS+ C C G + DP
Sbjct: 606 LECPQGYKRLNLTHCQDINEC-LTLGLCKDAE-CVNTRGSYLC----TCRPGLMLDPSRS 659
Query: 854 NCVDINECTSLSEPCRPGFSCINTVGSYTC 883
CV + L C ++G TC
Sbjct: 660 RCVSDKAISMLQG------LCYRSLGPGTC 683
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 262 bits (669), Expect = 2e-69
Identities = 144/422 (34%), Positives = 207/422 (49%), Gaps = 55/422 (13%)
Query: 827 LCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQ- 884
LC + G+ A+ +C +GF L G C+DI+EC ++ E CR C+N G Y C
Sbjct: 15 LCLPSPGN----AQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIP 70
Query: 885 -------------------------------------RNPLICARGYHASDDGTKCVDVN 907
PLIC GY D+ +CVDV+
Sbjct: 71 RTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQM-DESNQCVDVD 129
Query: 908 ECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENT 967
EC T H+C Q+C N G Y C C G+ C+D++EC CQ C N
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYG---YCQQLCANV 184
Query: 968 LGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQECANIYGSYQCYCRQGYQLAEDGHT 1026
GSY C+C GF L DG+ C+DVNEC + C Q C N YGS+ C C GY+L EDG
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVH 244
Query: 1027 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1086
C+D+DEC+ LC C+N PG+Y C+CP GY + + RSC+D++EC H C+
Sbjct: 245 CSDMDECSFSE-FLCQHECVNQPGTYFCSCPP-GYILLDDNRSCQDINECEHRNHTCNLQ 302
Query: 1087 ETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL 1145
+TC+N+QG F+C+ C Y+++S +C + C++ P I + ++ +G
Sbjct: 303 QTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA--ENPGCRDQPFTILYRDMDVVSGRS 360
Query: 1146 VPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDV 1205
VPA IF++ + G I GNE F R+ + + + R + PR+ LD+
Sbjct: 361 VPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDL 420
Query: 1206 EM 1207
EM
Sbjct: 421 EM 422
Score = 164 bits (414), Expect = 6e-40
Identities = 104/340 (30%), Positives = 146/340 (42%), Gaps = 68/340 (20%)
Query: 692 VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHT-- 749
+C G+A C G+ + C D DEC C CVN G + C+ T
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 750 ------------------------------------VLCADGYILNAHRKCVDINECVTD 773
++C GY ++ +CVD++EC TD
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATD 134
Query: 774 LHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKG 833
H C+ + C+NT G + C +C GY L +G+C D+DEC G CQ LC N G
Sbjct: 135 SHQCNPTQICINTEGGYTC----SCTDGYWLLEGQCLDIDECRYG--YCQQ--LCANVPG 186
Query: 834 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
S+ C C GF + +G +C D+NEC + PC +C+NT GS+ C+ C
Sbjct: 187 SYSC----TCNPGFTLNEDGRSCQDVNECAT-ENPCVQ--TCVNTYGSFICR-----CDP 234
Query: 893 GYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 952
GY +DG C D++EC C C N PG+Y C C G+ R C D+NEC
Sbjct: 235 GYELEEDGVHCSDMDECSFSEFLC--QHECVNQPGTYFCSCPPGYILLDDNRSCQDINEC 292
Query: 953 WASPGRLC--QHTCENTLGSYRC----SCASGFLLAADGK 986
C Q TC N G ++C C +L +D +
Sbjct: 293 -EHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 144 bits (362), Expect = 7e-34
Identities = 110/333 (33%), Positives = 146/333 (43%), Gaps = 65/333 (19%)
Query: 604 DQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
D DEC +P E C+ +C+N G Y C P +P P
Sbjct: 42 DIDECRTIP-EACRGDMMCVNQNGGYLCI---------------PRTNPVY-RGPYSNPY 84
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
+ +S P P P N P T+ IC GY M + C D D
Sbjct: 85 STPYSG------PYPAAAPPLSAPNYP------TISRPLICRF--GYQ-MDESNQCVDVD 129
Query: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGE 781
EC +H C+ Q C+NT G + C C DGY L +C+DI+EC C +
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTC-----SCTDGYWL-LEGQCLDIDEC--RYGYCQ--Q 179
Query: 782 HCVNTLGSFHCYKALTCEPGYAL-KDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 839
C N GS+ C TC PG+ L +DG C+DV+ECA Q C NT GSF C
Sbjct: 180 LCANVPGSYSC----TCNPGFTLNEDGRSCQDVNECATENPCVQ---TCVNTYGSFIC-- 230
Query: 840 RQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASD 898
RC G+ + +G +C D++EC+ C+ C+N G+Y C C GY D
Sbjct: 231 --RCDPGYELEEDGVHCSDMDECSFSEFLCQ--HECVNQPGTYFCS-----CPPGYILLD 281
Query: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC 931
D C D+NECE H C Q C+NL G ++C
Sbjct: 282 DNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 130 bits (327), Expect = 8e-30
Identities = 75/208 (36%), Positives = 89/208 (42%), Gaps = 45/208 (21%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC CQ LC N GSY C C PGF+L +DGR+C+
Sbjct: 168 DIDECRY---GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQ------------------ 206
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDEC 723
N C PC Q C GS IC C PGY + DGV C D DEC
Sbjct: 207 ---------------DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDEC 251
Query: 724 LMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYI-LNAHRKCVDINECVTDLHTCSRGEH 782
C CVN G+++C C GYI L+ +R C DINEC HTC+ +
Sbjct: 252 SFSEFLCQHE--CVNQPGTYFC-----SCPPGYILLDDNRSCQDINECEHRNHTCNLQQT 304
Query: 783 CVNTLGSFHCYKALTCEPGY-ALKDGEC 809
C N G F C + CE Y + D C
Sbjct: 305 CYNLQGGFKCIDPIRCEEPYLRISDNRC 332
>gi|86788132 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 808 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 857
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 858 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 891
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 892 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 951
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 952 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 1010
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1071 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1129
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1130 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1189
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1190 YLQRAVLEPRDFALDVEM 1207
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 152 bits (384), Expect = 2e-36
Identities = 106/371 (28%), Positives = 161/371 (43%), Gaps = 63/371 (16%)
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHT-------------- 749
C GY C+D DEC + C CVN G + C+ T
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 750 -----------------------VLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNT 786
VL G++ +A + + R
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 787 LGSFHCYKALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
+ S ++ + C GY + C+D+DEC GTH C+ +C N +GSF CQ C
Sbjct: 149 IPSNPSHR-IQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ----CPP 203
Query: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD 905
G+ + E CVDI+ECT + C C+NT GS+ CQ C+ G+ + + CVD
Sbjct: 204 GYQKRGE-QCVDIDECT-IPPYCHQ--RCVNTPGSFYCQ-----CSPGFQLAANNYTCVD 254
Query: 906 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 965
+NEC+ ++C Q C+N+ GS+ C C G++ + C D++EC S LCQ+ C
Sbjct: 255 INECDAS-NQC--AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTS-SYLCQYQCV 310
Query: 966 NTLGSYRCSCASGFLLAADGKRCEDVNECE-AQRCSQE--CANIYGSYQCYCRQGYQLAE 1022
N G + C C G+ + + C+D+NECE C ++ C N +G ++CY R Q
Sbjct: 311 NEPGKFSCMCPQGYQVVR-SRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQ--- 366
Query: 1023 DGHTCTDIDEC 1033
D + T + C
Sbjct: 367 DPYILTPENRC 377
Score = 112 bits (280), Expect = 2e-24
Identities = 92/308 (29%), Positives = 123/308 (39%), Gaps = 64/308 (20%)
Query: 565 RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGEL-CQHLCINT 623
R P +P P S R + G E N D DEC +CIN
Sbjct: 141 RNPADPQRIPSNPSH-----RIQCAAGYEQSEHNVC--QDIDECTAGTHNCRADQVCINL 193
Query: 624 VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC 683
GS+ C C PG+ Q G C + TIP
Sbjct: 194 RGSFACQCPPGY--QKRGEQC---------------------VDIDECTIP--------- 221
Query: 684 KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
C Q C GS C C PG+ + A+ +C D +EC ++ C+++ C N LGSF
Sbjct: 222 ---PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQ--CYNILGSF 275
Query: 744 YCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C C GY L++ R C DI+EC T + C CVN G F C C GY
Sbjct: 276 ICQ-----CNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCM----CPQGY 324
Query: 803 -ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
++ C+D++EC T+ C+ +C N G F C R C D ++ PE CV C
Sbjct: 325 QVVRSRTCQDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----C 379
Query: 862 TSLSEPCR 869
+ CR
Sbjct: 380 PVSNAMCR 387
>gi|86788015 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 808 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 857
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 858 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 891
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 892 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 951
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 952 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 1010
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1071 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1129
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1130 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1189
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1190 YLQRAVLEPRDFALDVEM 1207
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 152 bits (384), Expect = 2e-36
Identities = 106/371 (28%), Positives = 161/371 (43%), Gaps = 63/371 (16%)
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHT-------------- 749
C GY C+D DEC + C CVN G + C+ T
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 750 -----------------------VLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNT 786
VL G++ +A + + R
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 787 LGSFHCYKALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
+ S ++ + C GY + C+D+DEC GTH C+ +C N +GSF CQ C
Sbjct: 149 IPSNPSHR-IQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ----CPP 203
Query: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD 905
G+ + E CVDI+ECT + C C+NT GS+ CQ C+ G+ + + CVD
Sbjct: 204 GYQKRGE-QCVDIDECT-IPPYCHQ--RCVNTPGSFYCQ-----CSPGFQLAANNYTCVD 254
Query: 906 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 965
+NEC+ ++C Q C+N+ GS+ C C G++ + C D++EC S LCQ+ C
Sbjct: 255 INECDAS-NQC--AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTS-SYLCQYQCV 310
Query: 966 NTLGSYRCSCASGFLLAADGKRCEDVNECE-AQRCSQE--CANIYGSYQCYCRQGYQLAE 1022
N G + C C G+ + + C+D+NECE C ++ C N +G ++CY R Q
Sbjct: 311 NEPGKFSCMCPQGYQVVR-SRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQ--- 366
Query: 1023 DGHTCTDIDEC 1033
D + T + C
Sbjct: 367 DPYILTPENRC 377
Score = 112 bits (280), Expect = 2e-24
Identities = 92/308 (29%), Positives = 123/308 (39%), Gaps = 64/308 (20%)
Query: 565 RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGEL-CQHLCINT 623
R P +P P S R + G E N D DEC +CIN
Sbjct: 141 RNPADPQRIPSNPSH-----RIQCAAGYEQSEHNVC--QDIDECTAGTHNCRADQVCINL 193
Query: 624 VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC 683
GS+ C C PG+ Q G C + TIP
Sbjct: 194 RGSFACQCPPGY--QKRGEQC---------------------VDIDECTIP--------- 221
Query: 684 KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
C Q C GS C C PG+ + A+ +C D +EC ++ C+++ C N LGSF
Sbjct: 222 ---PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQ--CYNILGSF 275
Query: 744 YCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C C GY L++ R C DI+EC T + C CVN G F C C GY
Sbjct: 276 ICQ-----CNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCM----CPQGY 324
Query: 803 -ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
++ C+D++EC T+ C+ +C N G F C R C D ++ PE CV C
Sbjct: 325 QVVRSRTCQDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----C 379
Query: 862 TSLSEPCR 869
+ CR
Sbjct: 380 PVSNAMCR 387
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein 1
precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 808 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 857
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 858 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 891
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 892 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 951
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 952 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 1010
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 1011 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1071 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1129
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1130 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1189
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1190 YLQRAVLEPRDFALDVEM 1207
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 152 bits (384), Expect = 2e-36
Identities = 106/371 (28%), Positives = 161/371 (43%), Gaps = 63/371 (16%)
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHT-------------- 749
C GY C+D DEC + C CVN G + C+ T
Sbjct: 29 CTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET 88
Query: 750 -----------------------VLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNT 786
VL G++ +A + + R
Sbjct: 89 QPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQR 148
Query: 787 LGSFHCYKALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
+ S ++ + C GY + C+D+DEC GTH C+ +C N +GSF CQ C
Sbjct: 149 IPSNPSHR-IQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQ----CPP 203
Query: 846 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD 905
G+ + E CVDI+ECT + C C+NT GS+ CQ C+ G+ + + CVD
Sbjct: 204 GYQKRGE-QCVDIDECT-IPPYCHQ--RCVNTPGSFYCQ-----CSPGFQLAANNYTCVD 254
Query: 906 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 965
+NEC+ ++C Q C+N+ GS+ C C G++ + C D++EC S LCQ+ C
Sbjct: 255 INECDAS-NQC--AQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTS-SYLCQYQCV 310
Query: 966 NTLGSYRCSCASGFLLAADGKRCEDVNECE-AQRCSQE--CANIYGSYQCYCRQGYQLAE 1022
N G + C C G+ + + C+D+NECE C ++ C N +G ++CY R Q
Sbjct: 311 NEPGKFSCMCPQGYQVVR-SRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQ--- 366
Query: 1023 DGHTCTDIDEC 1033
D + T + C
Sbjct: 367 DPYILTPENRC 377
Score = 112 bits (280), Expect = 2e-24
Identities = 92/308 (29%), Positives = 123/308 (39%), Gaps = 64/308 (20%)
Query: 565 RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGEL-CQHLCINT 623
R P +P P S R + G E N D DEC +CIN
Sbjct: 141 RNPADPQRIPSNPSH-----RIQCAAGYEQSEHNVC--QDIDECTAGTHNCRADQVCINL 193
Query: 624 VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC 683
GS+ C C PG+ Q G C + TIP
Sbjct: 194 RGSFACQCPPGY--QKRGEQC---------------------VDIDECTIP--------- 221
Query: 684 KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
C Q C GS C C PG+ + A+ +C D +EC ++ C+++ C N LGSF
Sbjct: 222 ---PYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQ--CYNILGSF 275
Query: 744 YCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
C C GY L++ R C DI+EC T + C CVN G F C C GY
Sbjct: 276 ICQ-----CNQGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCM----CPQGY 324
Query: 803 -ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC 861
++ C+D++EC T+ C+ +C N G F C R C D ++ PE CV C
Sbjct: 325 QVVRSRTCQDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCV----C 379
Query: 862 TSLSEPCR 869
+ CR
Sbjct: 380 PVSNAMCR 387
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 231 bits (588), Expect = 4e-60
Identities = 147/466 (31%), Positives = 201/466 (43%), Gaps = 69/466 (14%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C H CIN GSY C C G+ L D TCR
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRI----------------------------- 279
Query: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQF 735
Q ++ C+Q+C V GS +C C+ GYA+ DG C D C H C
Sbjct: 280 ---QDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE-- 334
Query: 736 CVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCVNTLGSF--HC 792
CVN GS+ C C +G+ LN +K C I+ C + H C CVNT S+ HC
Sbjct: 335 CVNADGSYLC-----QCHEGFALNPDKKTCTKIDYCASSNHGCQ--HECVNTDDSYSCHC 387
Query: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
K T P C ++ CA+ C+ C N + S+YC RC G+ DP
Sbjct: 388 LKGFTLNP----DKKTCRRINYCALNKPGCE--HECVNMEESYYC----RCHRGYTLDPN 437
Query: 853 G-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET 911
G C ++ C C C+NT S+ CQ C+ G+ ++D C V+ C
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ-----CSEGFLINEDLKTCSRVDYCLL 490
Query: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSY 971
H C C N+ S+ C C G + G+ C ++ C A C+H+C ++ S+
Sbjct: 491 SDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSC-ALGDHGCEHSCVSSEDSF 547
Query: 972 RCSCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTD 1029
C C G++L DGK C + C+A C C N SY C C +G++LAEDG C
Sbjct: 548 VCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRR 607
Query: 1030 IDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1075
D C + C C+N SY C C E G+ + +GR CK E
Sbjct: 608 KDVC-KSTHHGCEHICVNNGNSYICKCSE-GFVLAEDGRRCKKCTE 651
Score = 221 bits (562), Expect = 4e-57
Identities = 143/438 (32%), Positives = 195/438 (44%), Gaps = 43/438 (9%)
Query: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNH 748
C C + GS +C C GY + +D +C QD C M H+C Q CVN GSF C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC--EQLCVNVPGSFVC--- 303
Query: 749 TVLCADGYIL-NAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG 807
C GY L ++CV ++ C ++ H C CVN GS+ C C G+AL
Sbjct: 304 --QCYSGYALAEDGKRCVAVDYCASENHGCE--HECVNADGSYLC----QCHEGFALNPD 355
Query: 808 E--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE-GNCVDINECTSL 864
+ C +D CA H CQ C NT S+ C C+ GF +P+ C IN C
Sbjct: 356 KKTCTKIDYCASSNHGCQ--HECVNTDDSYSC----HCLKGFTLNPDKKTCRRINYCALN 409
Query: 865 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 924
C C+N SY C+ C RGY +G C V+ C H C Q+C N
Sbjct: 410 KPGCE--HECVNMEESYYCR-----CHRGYTLDPNGKTCSRVDHCAQQDHGC--EQLCLN 460
Query: 925 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAAD 984
S+ C C GF + + C V+ C S C+++C N S+ C C G +L +D
Sbjct: 461 TEDSFVCQCSEGFLINEDLKTCSRVDYCLLS-DHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Query: 985 GKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCT 1042
GK C ++ C C C + S+ C C +GY L EDG TC D C Q C
Sbjct: 520 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC-QAIDHGCE 578
Query: 1043 FRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFE 1102
C+N SY C C E G+ + +G+ C+ D C H C C N S+ C +
Sbjct: 579 HICVNSDDSYTCECLE-GFRLAEDGKRCRRKDVCKSTHHGCE--HICVNNGNSYIC---K 632
Query: 1103 CPPNYVQVSK-TKCERTT 1119
C +V +C++ T
Sbjct: 633 CSEGFVLAEDGRRCKKCT 650
Score = 207 bits (526), Expect = 6e-53
Identities = 136/438 (31%), Positives = 185/438 (42%), Gaps = 71/438 (16%)
Query: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
QD C + C+ LC+N GS+ C C+ G++L +DG+ C
Sbjct: 280 QDLCAM-EDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------- 318
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
+ +N C+ C GS +C C G+A+ D +C D C
Sbjct: 319 ------------VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHC 783
H C CVNT S+ C C G+ LN +K C IN C + C C
Sbjct: 367 SSNHGCQHE--CVNTDDSYSC-----HCLKGFTLNPDKKTCRRINYCALNKPGCE--HEC 417
Query: 784 VNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
VN S++C C GY L C VD CA H C+ LC NT+ SF CQ
Sbjct: 418 VNMEESYYC----RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ--- 468
Query: 842 RCMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
C +GFL + + C ++ C C +SC+N S+ CQ C G+ DG
Sbjct: 469 -CSEGFLINEDLKTCSRVDYCLLSDHGCE--YSCVNMDRSFACQ-----CPEGHVLRSDG 520
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
C ++ C G H C C + S+ C C G+ G+ C + C A C
Sbjct: 521 KTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI-DHGC 577
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGY 1018
+H C N+ SY C C GF LA DGKRC + C++ C C N SY C C +G+
Sbjct: 578 EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Query: 1019 QLAEDGHTCTDIDECAQG 1036
LAEDG C +C +G
Sbjct: 638 VLAEDGRRC---KKCTEG 652
Score = 178 bits (452), Expect = 2e-44
Identities = 109/315 (34%), Positives = 144/315 (45%), Gaps = 30/315 (9%)
Query: 815 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE-CTSLSEPCRPGFS 873
C+ H C C N GS+ C RC G++ + + I + C C
Sbjct: 242 CSTLEHNC--AHFCINIPGSYVC----RCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--L 293
Query: 874 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 933
C+N GS+ CQ C GY ++DG +CV V+ C + H C C N GSY C C
Sbjct: 294 CVNVPGSFVCQ-----CYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLCQC 346
Query: 934 KAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 993
GF + + C ++ C AS CQH C NT SY C C GF L D K C +N
Sbjct: 347 HEGFALNPDKKTCTKIDYC-ASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINY 405
Query: 994 CEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1051
C + C EC N+ SY C C +GY L +G TC+ +D CAQ C CLN S
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ-QDHGCEQLCLNTEDS 464
Query: 1052 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1111
+ C C E G+ + + ++C VD C L H C +C N+ SF C +CP +V S
Sbjct: 465 FVCQCSE-GFLINEDLKTCSRVDYCLLSDHGCE--YSCVNMDRSFAC---QCPEGHVLRS 518
Query: 1112 KTKCERTTCHDFLEC 1126
K TC C
Sbjct: 519 DGK----TCAKLDSC 529
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 231 bits (588), Expect = 4e-60
Identities = 147/466 (31%), Positives = 201/466 (43%), Gaps = 69/466 (14%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C H CIN GSY C C G+ L D TCR
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRI----------------------------- 279
Query: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQF 735
Q ++ C+Q+C V GS +C C+ GYA+ DG C D C H C
Sbjct: 280 ---QDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE-- 334
Query: 736 CVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCVNTLGSF--HC 792
CVN GS+ C C +G+ LN +K C I+ C + H C CVNT S+ HC
Sbjct: 335 CVNADGSYLC-----QCHEGFALNPDKKTCTKIDYCASSNHGCQ--HECVNTDDSYSCHC 387
Query: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE 852
K T P C ++ CA+ C+ C N + S+YC RC G+ DP
Sbjct: 388 LKGFTLNP----DKKTCRRINYCALNKPGCE--HECVNMEESYYC----RCHRGYTLDPN 437
Query: 853 G-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET 911
G C ++ C C C+NT S+ CQ C+ G+ ++D C V+ C
Sbjct: 438 GKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ-----CSEGFLINEDLKTCSRVDYCLL 490
Query: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSY 971
H C C N+ S+ C C G + G+ C ++ C A C+H+C ++ S+
Sbjct: 491 SDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSC-ALGDHGCEHSCVSSEDSF 547
Query: 972 RCSCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTD 1029
C C G++L DGK C + C+A C C N SY C C +G++LAEDG C
Sbjct: 548 VCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRR 607
Query: 1030 IDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1075
D C + C C+N SY C C E G+ + +GR CK E
Sbjct: 608 KDVC-KSTHHGCEHICVNNGNSYICKCSE-GFVLAEDGRRCKKCTE 651
Score = 221 bits (562), Expect = 4e-57
Identities = 143/438 (32%), Positives = 195/438 (44%), Gaps = 43/438 (9%)
Query: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNH 748
C C + GS +C C GY + +D +C QD C M H+C Q CVN GSF C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC--EQLCVNVPGSFVC--- 303
Query: 749 TVLCADGYIL-NAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG 807
C GY L ++CV ++ C ++ H C CVN GS+ C C G+AL
Sbjct: 304 --QCYSGYALAEDGKRCVAVDYCASENHGCE--HECVNADGSYLC----QCHEGFALNPD 355
Query: 808 E--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE-GNCVDINECTSL 864
+ C +D CA H CQ C NT S+ C C+ GF +P+ C IN C
Sbjct: 356 KKTCTKIDYCASSNHGCQ--HECVNTDDSYSC----HCLKGFTLNPDKKTCRRINYCALN 409
Query: 865 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 924
C C+N SY C+ C RGY +G C V+ C H C Q+C N
Sbjct: 410 KPGCE--HECVNMEESYYCR-----CHRGYTLDPNGKTCSRVDHCAQQDHGC--EQLCLN 460
Query: 925 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAAD 984
S+ C C GF + + C V+ C S C+++C N S+ C C G +L +D
Sbjct: 461 TEDSFVCQCSEGFLINEDLKTCSRVDYCLLS-DHGCEYSCVNMDRSFACQCPEGHVLRSD 519
Query: 985 GKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCT 1042
GK C ++ C C C + S+ C C +GY L EDG TC D C Q C
Sbjct: 520 GKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC-QAIDHGCE 578
Query: 1043 FRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFE 1102
C+N SY C C E G+ + +G+ C+ D C H C C N S+ C +
Sbjct: 579 HICVNSDDSYTCECLE-GFRLAEDGKRCRRKDVCKSTHHGCE--HICVNNGNSYIC---K 632
Query: 1103 CPPNYVQVSK-TKCERTT 1119
C +V +C++ T
Sbjct: 633 CSEGFVLAEDGRRCKKCT 650
Score = 207 bits (526), Expect = 6e-53
Identities = 136/438 (31%), Positives = 185/438 (42%), Gaps = 71/438 (16%)
Query: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
QD C + C+ LC+N GS+ C C+ G++L +DG+ C
Sbjct: 280 QDLCAM-EDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------- 318
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
+ +N C+ C GS +C C G+A+ D +C D C
Sbjct: 319 ------------VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHC 783
H C CVNT S+ C C G+ LN +K C IN C + C C
Sbjct: 367 SSNHGCQHE--CVNTDDSYSC-----HCLKGFTLNPDKKTCRRINYCALNKPGCE--HEC 417
Query: 784 VNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 841
VN S++C C GY L C VD CA H C+ LC NT+ SF CQ
Sbjct: 418 VNMEESYYC----RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ--- 468
Query: 842 RCMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
C +GFL + + C ++ C C +SC+N S+ CQ C G+ DG
Sbjct: 469 -CSEGFLINEDLKTCSRVDYCLLSDHGCE--YSCVNMDRSFACQ-----CPEGHVLRSDG 520
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
C ++ C G H C C + S+ C C G+ G+ C + C A C
Sbjct: 521 KTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI-DHGC 577
Query: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGY 1018
+H C N+ SY C C GF LA DGKRC + C++ C C N SY C C +G+
Sbjct: 578 EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGF 637
Query: 1019 QLAEDGHTCTDIDECAQG 1036
LAEDG C +C +G
Sbjct: 638 VLAEDGRRC---KKCTEG 652
Score = 178 bits (452), Expect = 2e-44
Identities = 109/315 (34%), Positives = 144/315 (45%), Gaps = 30/315 (9%)
Query: 815 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE-CTSLSEPCRPGFS 873
C+ H C C N GS+ C RC G++ + + I + C C
Sbjct: 242 CSTLEHNC--AHFCINIPGSYVC----RCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--L 293
Query: 874 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 933
C+N GS+ CQ C GY ++DG +CV V+ C + H C C N GSY C C
Sbjct: 294 CVNVPGSFVCQ-----CYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLCQC 346
Query: 934 KAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 993
GF + + C ++ C AS CQH C NT SY C C GF L D K C +N
Sbjct: 347 HEGFALNPDKKTCTKIDYC-ASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINY 405
Query: 994 CEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1051
C + C EC N+ SY C C +GY L +G TC+ +D CAQ C CLN S
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ-QDHGCEQLCLNTEDS 464
Query: 1052 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1111
+ C C E G+ + + ++C VD C L H C +C N+ SF C +CP +V S
Sbjct: 465 FVCQCSE-GFLINEDLKTCSRVDYCLLSDHGCE--YSCVNMDRSFAC---QCPEGHVLRS 518
Query: 1112 KTKCERTTCHDFLEC 1126
K TC C
Sbjct: 519 DGK----TCAKLDSC 529
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 798 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 854
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 3481
Query: 855 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 914
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 3482 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 3537
Query: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 974
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 3538 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 3596
Query: 975 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 1010
C G L DGK C + E Q + + A+I G SY
Sbjct: 3597 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 3655
Query: 1011 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1064
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 3656 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 3710
Query: 1065 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1123
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 3711 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 3769
Query: 1124 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1178
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 3770 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 3825
Query: 1179 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1219
R L A G VY +RA+ + L V R SV L
Sbjct: 3826 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 3866
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 884 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 943
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 3422 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 3479
Query: 944 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 995
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 3480 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 3537
Query: 996 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1055
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 3538 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 3596
Query: 1056 CPEQGYTMTANGRSCKDVD 1074
CP G T+ +G++C ++
Sbjct: 3597 CP-PGQTLLRDGKACTSLE 3614
Score = 130 bits (326), Expect = 1e-29
Identities = 122/445 (27%), Positives = 160/445 (35%), Gaps = 123/445 (27%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 3375 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 3434
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
G D+DEC P C H C+N G + C C GF+L D R CR
Sbjct: 3435 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCR---------- 3483
Query: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAIC--SCFPGYAIMAD 713
+ + A + + C++ Q C + GS C C PG+ + AD
Sbjct: 3484 --------DVDECAWDA--------HLCREG----QRCVNLLGSYRCLPDCGPGFRV-AD 3522
Query: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINE--- 769
G CED DECL G DC Q C NT G C C GY + C+D+NE
Sbjct: 3523 GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-----CPRGYRMQGPSLPCLDVNECLQ 3577
Query: 770 ----CVTDLHTCSRGEHCVNTLG------------------------------------- 788
C H C+ G
Sbjct: 3578 LPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWA 3637
Query: 789 -----SFHCYKALT-------------CEPGYALKDGECEDVDECAMGTHTCQPGFLCQN 830
S+H + +L C PG+ ++G C D+DEC + + CQ C+N
Sbjct: 3638 SIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNGVCTDLDECRV-RNLCQHA--CRN 3694
Query: 831 TKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
T+GS+ C C G+ P G NC DINEC S C PG C NT GSY C P
Sbjct: 3695 TEGSYQCL----CPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP-- 3748
Query: 890 CARGYHASDDGTKCVD--VNECETG 912
C Y C +C TG
Sbjct: 3749 CPATYRQGPSPGTCFRRCSQDCGTG 3773
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 993 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1052
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 3407 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 3465
Query: 1053 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1112
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 3466 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 3523
Query: 1113 TKCERT--------TCHDFLECQNSP 1130
CE CH C+N+P
Sbjct: 3524 AGCEDVDECLEGLDDCHYNQLCENTP 3549
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/320 (26%), Positives = 116/320 (36%), Gaps = 74/320 (23%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV-LGAKEGETCGA 504
C G A D+ C ++ E + ++CR QR CV+ L C+ G + + G
Sbjct: 3469 CPTGFALAWDDRNCRDVDECAWDAHLCREGQR--CVNLLGSYRCLPDCGPGFRVADGAGC 3526
Query: 505 EDNDSCGISL----YKQCCD--------CCGLGLRVRAEGQSC-ESNPNL------GYPC 545
ED D C L Y Q C+ C G R++ C + N L Y C
Sbjct: 3527 EDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQC 3586
Query: 546 NHVMLS----CCEGE----------------EPLIVPEVRRPPEP-----AAAPRRVSEA 580
+++ S C G+ + + R P P A+ P A
Sbjct: 3587 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 3646
Query: 581 EMA---GREALSLGTEAELPNSLPG--------DDQDECLLLPGELCQHLCINTVGSYHC 629
++ G ALS A P PG D DEC + LCQH C NT GSY C
Sbjct: 3647 WVSLRPGPMALSSVGRAWCP---PGFIRQNGVCTDLDECRVR--NLCQHACRNTEGSYQC 3701
Query: 630 ACFPGFSLQDDGRTCRPEGHPPQPE---APQEPALKSEFSQVASNTIPLPL-----PQPN 681
C G+ L G+ C+ + P + + S +T P P P P
Sbjct: 3702 LCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDT-PCPATYRQGPSPG 3760
Query: 682 TCKDNGPCKQVCSTVGGSAI 701
TC C Q C T G S +
Sbjct: 3761 TCFRR--CSQDCGTGGPSTL 3778
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 798 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 854
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 4672
Query: 855 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 914
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 4673 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 4728
Query: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 974
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 4729 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 4787
Query: 975 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 1010
C G L DGK C + E Q + + A+I G SY
Sbjct: 4788 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 4846
Query: 1011 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1064
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 4847 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 4901
Query: 1065 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1123
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 4902 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 4960
Query: 1124 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1178
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 4961 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 5016
Query: 1179 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1219
R L A G VY +RA+ + L V R SV L
Sbjct: 5017 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 5057
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 884 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 943
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 4613 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 4670
Query: 944 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 995
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 4671 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 4728
Query: 996 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1055
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 4729 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 4787
Query: 1056 CPEQGYTMTANGRSCKDVD 1074
CP G T+ +G++C ++
Sbjct: 4788 CP-PGQTLLRDGKACTSLE 4805
Score = 130 bits (326), Expect = 1e-29
Identities = 122/445 (27%), Positives = 160/445 (35%), Gaps = 123/445 (27%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 4566 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 4625
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
G D+DEC P C H C+N G + C C GF+L D R CR
Sbjct: 4626 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCR---------- 4674
Query: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAIC--SCFPGYAIMAD 713
+ + A + + C++ Q C + GS C C PG+ + AD
Sbjct: 4675 --------DVDECAWDA--------HLCREG----QRCVNLLGSYRCLPDCGPGFRV-AD 4713
Query: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINE--- 769
G CED DECL G DC Q C NT G C C GY + C+D+NE
Sbjct: 4714 GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-----CPRGYRMQGPSLPCLDVNECLQ 4768
Query: 770 ----CVTDLHTCSRGEHCVNTLG------------------------------------- 788
C H C+ G
Sbjct: 4769 LPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWA 4828
Query: 789 -----SFHCYKALT-------------CEPGYALKDGECEDVDECAMGTHTCQPGFLCQN 830
S+H + +L C PG+ ++G C D+DEC + + CQ C+N
Sbjct: 4829 SIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNGVCTDLDECRV-RNLCQHA--CRN 4885
Query: 831 TKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
T+GS+ C C G+ P G NC DINEC S C PG C NT GSY C P
Sbjct: 4886 TEGSYQCL----CPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP-- 4939
Query: 890 CARGYHASDDGTKCVD--VNECETG 912
C Y C +C TG
Sbjct: 4940 CPATYRQGPSPGTCFRRCSQDCGTG 4964
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 993 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1052
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 4598 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 4656
Query: 1053 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1112
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 4657 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 4714
Query: 1113 TKCERT--------TCHDFLECQNSP 1130
CE CH C+N+P
Sbjct: 4715 AGCEDVDECLEGLDDCHYNQLCENTP 4740
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/320 (26%), Positives = 116/320 (36%), Gaps = 74/320 (23%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV-LGAKEGETCGA 504
C G A D+ C ++ E + ++CR QR CV+ L C+ G + + G
Sbjct: 4660 CPTGFALAWDDRNCRDVDECAWDAHLCREGQR--CVNLLGSYRCLPDCGPGFRVADGAGC 4717
Query: 505 EDNDSCGISL----YKQCCD--------CCGLGLRVRAEGQSC-ESNPNL------GYPC 545
ED D C L Y Q C+ C G R++ C + N L Y C
Sbjct: 4718 EDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQC 4777
Query: 546 NHVMLS----CCEGE----------------EPLIVPEVRRPPEP-----AAAPRRVSEA 580
+++ S C G+ + + R P P A+ P A
Sbjct: 4778 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 4837
Query: 581 EMA---GREALSLGTEAELPNSLPG--------DDQDECLLLPGELCQHLCINTVGSYHC 629
++ G ALS A P PG D DEC + LCQH C NT GSY C
Sbjct: 4838 WVSLRPGPMALSSVGRAWCP---PGFIRQNGVCTDLDECRVR--NLCQHACRNTEGSYQC 4892
Query: 630 ACFPGFSLQDDGRTCRPEGHPPQPE---APQEPALKSEFSQVASNTIPLPL-----PQPN 681
C G+ L G+ C+ + P + + S +T P P P P
Sbjct: 4893 LCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDT-PCPATYRQGPSPG 4951
Query: 682 TCKDNGPCKQVCSTVGGSAI 701
TC C Q C T G S +
Sbjct: 4952 TCFRR--CSQDCGTGGPSTL 4969
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 798 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 854
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 3390
Query: 855 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 914
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 3391 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 3446
Query: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 974
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 3447 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 3505
Query: 975 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 1010
C G L DGK C + E Q + + A+I G SY
Sbjct: 3506 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 3564
Query: 1011 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1064
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 3565 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 3619
Query: 1065 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1123
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 3620 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 3678
Query: 1124 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1178
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 3679 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 3734
Query: 1179 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1219
R L A G VY +RA+ + L V R SV L
Sbjct: 3735 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 3775
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 884 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 943
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 3331 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 3388
Query: 944 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 995
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 3389 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 3446
Query: 996 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1055
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 3447 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 3505
Query: 1056 CPEQGYTMTANGRSCKDVD 1074
CP G T+ +G++C ++
Sbjct: 3506 CP-PGQTLLRDGKACTSLE 3523
Score = 130 bits (326), Expect = 1e-29
Identities = 122/445 (27%), Positives = 160/445 (35%), Gaps = 123/445 (27%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 3284 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 3343
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
G D+DEC P C H C+N G + C C GF+L D R CR
Sbjct: 3344 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCR---------- 3392
Query: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAIC--SCFPGYAIMAD 713
+ + A + + C++ Q C + GS C C PG+ + AD
Sbjct: 3393 --------DVDECAWDA--------HLCREG----QRCVNLLGSYRCLPDCGPGFRV-AD 3431
Query: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDINE--- 769
G CED DECL G DC Q C NT G C C GY + C+D+NE
Sbjct: 3432 GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS-----CPRGYRMQGPSLPCLDVNECLQ 3486
Query: 770 ----CVTDLHTCSRGEHCVNTLG------------------------------------- 788
C H C+ G
Sbjct: 3487 LPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWA 3546
Query: 789 -----SFHCYKALT-------------CEPGYALKDGECEDVDECAMGTHTCQPGFLCQN 830
S+H + +L C PG+ ++G C D+DEC + + CQ C+N
Sbjct: 3547 SIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNGVCTDLDECRV-RNLCQHA--CRN 3603
Query: 831 TKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLI 889
T+GS+ C C G+ P G NC DINEC S C PG C NT GSY C P
Sbjct: 3604 TEGSYQCL----CPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP-- 3657
Query: 890 CARGYHASDDGTKCVD--VNECETG 912
C Y C +C TG
Sbjct: 3658 CPATYRQGPSPGTCFRRCSQDCGTG 3682
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 993 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1052
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 3316 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 3374
Query: 1053 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1112
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 3375 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 3432
Query: 1113 TKCERT--------TCHDFLECQNSP 1130
CE CH C+N+P
Sbjct: 3433 AGCEDVDECLEGLDDCHYNQLCENTP 3458
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/320 (26%), Positives = 116/320 (36%), Gaps = 74/320 (23%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV-LGAKEGETCGA 504
C G A D+ C ++ E + ++CR QR CV+ L C+ G + + G
Sbjct: 3378 CPTGFALAWDDRNCRDVDECAWDAHLCREGQR--CVNLLGSYRCLPDCGPGFRVADGAGC 3435
Query: 505 EDNDSCGISL----YKQCCD--------CCGLGLRVRAEGQSC-ESNPNL------GYPC 545
ED D C L Y Q C+ C G R++ C + N L Y C
Sbjct: 3436 EDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQC 3495
Query: 546 NHVMLS----CCEGE----------------EPLIVPEVRRPPEP-----AAAPRRVSEA 580
+++ S C G+ + + R P P A+ P A
Sbjct: 3496 HNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHA 3555
Query: 581 EMA---GREALSLGTEAELPNSLPG--------DDQDECLLLPGELCQHLCINTVGSYHC 629
++ G ALS A P PG D DEC + LCQH C NT GSY C
Sbjct: 3556 WVSLRPGPMALSSVGRAWCP---PGFIRQNGVCTDLDECRVR--NLCQHACRNTEGSYQC 3610
Query: 630 ACFPGFSLQDDGRTCRPEGHPPQPE---APQEPALKSEFSQVASNTIPLPL-----PQPN 681
C G+ L G+ C+ + P + + S +T P P P P
Sbjct: 3611 LCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDT-PCPATYRQGPSPG 3669
Query: 682 TCKDNGPCKQVCSTVGGSAI 701
TC C Q C T G S +
Sbjct: 3670 TCFRR--CSQDCGTGGPSTL 3687
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 202 bits (514), Expect = 2e-51
Identities = 136/432 (31%), Positives = 181/432 (41%), Gaps = 75/432 (17%)
Query: 719 DQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCS 778
D DEC G DC C NT S+ C LC GY ++C DI+EC D +
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKC-----LCKPGY-KGEGKQCEDIDECENDYYNGG 86
Query: 779 RGEHCVNTLGSFHCYKALTCEPGYAL-KDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFY 836
C+N G++ C TC G+ L DG C DVDEC CQ +C N GS+
Sbjct: 87 CVHECINIPGNYRC----TCFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYE 140
Query: 837 CQARQRCMDG-FLQDPEGNCVDINE-----------CTSLSE---------PCRPGF--- 872
CQ C G FL D + C+ + C + CRPGF
Sbjct: 141 CQ----CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLA 196
Query: 873 -------------------SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 913
SC +T TC C + Y DG C++ V
Sbjct: 197 QNQKDCTLTCNYGNGGCQHSCEDTDTGPTCG-----CHQKYALHSDGRTCIET----CAV 247
Query: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC 973
+ G + C + RC C GF G+ C D+NEC + G C H C NT+GS+ C
Sbjct: 248 NNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGG-CDHFCRNTVGSFEC 306
Query: 974 SCASGFLLAADGKRCEDVNECEAQR-CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDE 1032
C G+ L D + C+D++EC +R C C N GS+QC C +GY L H C D+DE
Sbjct: 307 GCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTH-CGDVDE 365
Query: 1033 CAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNI 1092
C+ G C C+N GSY+C CP G + NG+ C + +C A+ +
Sbjct: 366 CSMSNG-SCDQGCVNTKGSYECVCP-PGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSK 423
Query: 1093 QGSFRCLRFECP 1104
G CP
Sbjct: 424 AGGVESCFLSCP 435
Score = 185 bits (469), Expect = 3e-46
Identities = 115/357 (32%), Positives = 163/357 (45%), Gaps = 34/357 (9%)
Query: 765 VDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQP 824
VD++EC C C NT S+ C C+PGY + +CED+DEC +
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCL----CKPGYKGEGKQCEDIDECENDYYNGGC 87
Query: 825 GFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTC 883
C N G++ C C DGF+ +G NC+D++EC + C+ C+N +GSY C
Sbjct: 88 VHECINIPGNYRCT----CFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYEC 141
Query: 884 QRNPLICARGYHASDDGTKCVDVNE----CETGVHRCGEGQVCHNLP-GSYRCDCKAGFQ 938
Q C G+ SD+ C+ + C H C +C P G CDC+ GF
Sbjct: 142 Q-----CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--ICRETPKGGVACDCRPGFD 194
Query: 939 RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR 998
+ C C G CQH+CE+T C C + L +DG+ C +
Sbjct: 195 LAQNQKDC--TLTCNYGNGG-CQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGG 251
Query: 999 CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPE 1058
C + C + +C C G+ L DG TC DI+EC G C C N GS++C C
Sbjct: 252 CDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG-GCDHFCRNTVGSFECGC-R 309
Query: 1059 QGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1115
+GY + + R+C+D+DEC+ C C N GSF+CL C Y+ T C
Sbjct: 310 KGYKLLTDERTCQDIDECSF-ERTCD--HICINSPGSFQCL---CHRGYILYGTTHC 360
Score = 171 bits (434), Expect = 3e-42
Identities = 132/464 (28%), Positives = 191/464 (41%), Gaps = 80/464 (17%)
Query: 588 LSLGTEAELP--NSLPGD-DQDECLLLPGEL-CQHLCINTVGSYHCACFPGFSLQDDGRT 643
L+LGT L + LPG D DEC + +C NT SY C C PG+ + +G+
Sbjct: 14 LALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQ 71
Query: 644 CRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICS 703
C + + NG C C + G+ C+
Sbjct: 72 CED------------------------------IDECENDYYNGGCVHECINIPGNYRCT 101
Query: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK 763
CF G+ + DG +C D DEC C +Q CVN +GS+ C C G+ L+ ++
Sbjct: 102 CFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYEC-----QCHSGFFLSDNQH 154
Query: 764 CVDINECVTDLHTCSRGEHCVN-TLGSFHCYK-------ALTCEPGYALKDGECEDVDEC 815
T +H + G +C+N G H + A C PG+ L + + C
Sbjct: 155 --------TCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTC 206
Query: 816 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCI 875
G CQ C++T C Q+ L C++ C + C +C
Sbjct: 207 NYGNGGCQHS--CEDTDTGPTCGCHQKYA---LHSDGRTCIE--TCAVNNGGC--DRTCK 257
Query: 876 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 935
+T C C G+ DG C D+NEC V+ G C N GS+ C C+
Sbjct: 258 DTATGVRCS-----CPVGFTLQPDGKTCKDINECL--VNNGGCDHFCRNTVGSFECGCRK 310
Query: 936 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE 995
G++ R C D++EC S R C H C N+ GS++C C G++L C DV+EC
Sbjct: 311 GYKLLTDERTCQDIDEC--SFERTCDHICINSPGSFQCLCHRGYILYGT-THCGDVDECS 367
Query: 996 AQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA 1037
C Q C N GSY+C C G +L +G C + +C A
Sbjct: 368 MSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRA 411
Score = 143 bits (361), Expect = 9e-34
Identities = 132/471 (28%), Positives = 183/471 (38%), Gaps = 93/471 (19%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C H CIN G+Y C CF GF L DG C
Sbjct: 87 CVHECINIPGNYRCTCFDGFMLAHDGHNCL------------------------------ 116
Query: 676 PLPQPNTCKDN-GPCKQVCSTVGGSAICSCFPGYAIMADGVSC----EDQDECLMGAHDC 730
+ C+DN G C+Q+C GS C C G+ + + +C + C+ H C
Sbjct: 117 ---DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGC 173
Query: 731 SRRQFCVNT-LGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGE-HCVNTLG 788
+ C T G C C G+ L ++K +C TC+ G C ++
Sbjct: 174 A--HICRETPKGGVACD-----CRPGFDLAQNQK-----DCTL---TCNYGNGGCQHSCE 218
Query: 789 SFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 848
C YAL ++ CA+ C C++T C C GF
Sbjct: 219 DTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDR--TCKDTATGVRCS----CPVGFT 272
Query: 849 QDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVN 907
P+G C DINEC + C C NTVGS+ C C +GY D C D++
Sbjct: 273 LQPDGKTCKDINECLVNNGGC--DHFCRNTVGSFECG-----CRKGYKLLTDERTCQDID 325
Query: 908 ECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG-RGCIDVNECWASPGRLCQHTCEN 966
EC + C +C N PGS++C C G+ +G C DV+EC S G C C N
Sbjct: 326 EC-SFERTC--DHICINSPGSFQCLCHRGY--ILYGTTHCGDVDECSMSNGS-CDQGCVN 379
Query: 967 TLGSYRCSCASGFLLAADGKRCEDVNEC-----EAQRCSQECANIYGSYQCYCRQGYQLA 1021
T GSY C C G L +GK C + +C + R C+ G C+ L+
Sbjct: 380 TKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCF------LS 433
Query: 1022 EDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1072
HT D ++ + +L VPG A ++ T + G SC D
Sbjct: 434 CPAHTLFVPD--SENSYVL----SCGVPGPQGKALQKRNGTSSGLGPSCSD 478
Score = 125 bits (315), Expect = 2e-28
Identities = 130/471 (27%), Positives = 181/471 (38%), Gaps = 101/471 (21%)
Query: 448 AGQQWAIDNDECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSCMAGVLGAKEGETCGAED 506
+G ++D DEC E + D +C+ T + + C+ C G G EG+ C ED
Sbjct: 26 SGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCL-------CKPGYKG--EGKQC--ED 74
Query: 507 NDSCGISLYKQCC--DC----------CGLGLRVRAEGQSC-------ESNPNLGYPCNH 547
D C Y C +C C G + +G +C ++N C +
Sbjct: 75 IDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVN 134
Query: 548 VMLSC-CEGEEPLIVPE-----VRRPPEPAAAPRRVSEAEMAGREALSLGTEAEL-PNSL 600
M S C+ + + + R E + RE G + P
Sbjct: 135 AMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFD 194
Query: 601 PGDDQDECLLL---PGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQ 657
+Q +C L CQH C +T C C ++L DGRTC
Sbjct: 195 LAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCI------------ 242
Query: 658 EPALKSEFSQVASNTIPLPLPQPNTCK-DNGPCKQVCSTVGGSAICSCFPGYAIMADGVS 716
TC +NG C + C CSC G+ + DG +
Sbjct: 243 -----------------------ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKT 279
Query: 717 CEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGY-ILNAHRKCVDINECVTDLH 775
C+D +ECL+ C FC NT+GSF C C GY +L R C DI+EC +
Sbjct: 280 CKDINECLVNNGGCD--HFCRNTVGSFECG-----CRKGYKLLTDERTCQDIDECSFE-R 331
Query: 776 TCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGS 834
TC C+N+ GSF C C GY L C DVDEC+M +C G C NTKGS
Sbjct: 332 TCD--HICINSPGSFQC----LCHRGYILYGTTHCGDVDECSMSNGSCDQG--CVNTKGS 383
Query: 835 FYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPC-RPGFSCINTVGSYTC 883
+ C C G G +CV+ +C S ++ R SC G +C
Sbjct: 384 YECV----CPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 202 bits (513), Expect = 2e-51
Identities = 176/550 (32%), Positives = 226/550 (41%), Gaps = 96/550 (17%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ--DDGRTCRPEGHPPQPEAPQEPAL 661
D +EC P + +C+NT GSY+C C G+ L GR+C
Sbjct: 616 DVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC----------------- 658
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVS-CEDQ 720
+ ++ A +P+ C D G C G C+C+PGY + A CED
Sbjct: 659 -VDLNECA---------KPHLCGDGG----FCINFPGHYKCNCYPGYRLKASRPPVCEDI 704
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
DEC C + C N GSF C+ C GY C D+NEC CS G
Sbjct: 705 DEC-RDPSSCPDGK-CENKPGSFKCI----ACQPGYRSQGGGACRDVNECAEG-SPCSPG 757
Query: 781 EHCVNTLGSFHCYKALTCEPGYA-LKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
C N GSF C TC GYA DG C DVDEC G C G +C NT GSF CQ
Sbjct: 758 -WCENLPGSFRC----TCAQGYAPAPDGRSCLDVDECEAGD-VCDNG-ICSNTPGSFQCQ 810
Query: 839 ARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
C+ G+ L +C DI+EC C G CINT GSY C +C +G H
Sbjct: 811 ----CLSGYHLSRDRSHCEDIDEC-DFPAACIGG-DCINTNGSYRC-----LCPQG-HRL 858
Query: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV------NE 951
G KC D++EC C C NL GSY C C GF GC +V E
Sbjct: 859 VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKE 918
Query: 952 CWAS--PGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGS 1009
C+ + C + C C+ G A G CE + C ++
Sbjct: 919 CYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWGDHCE-IYPCPVYSSAE-------- 966
Query: 1010 YQCYCRQGYQLAEDGHTCT-------DIDECAQ-GAGILCTFRCLNVPGSYQCACPEQGY 1061
+ C G +D + DIDEC G+ I +C+N Y+C C +QG+
Sbjct: 967 FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYC-KQGF 1025
Query: 1062 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCH 1121
N C DVDEC L NC C N +G +RC PP ++ +C
Sbjct: 1026 YYDGNLLECVDVDEC-LDESNCRNG-VCENTRGGYRCAC--TPPAEYSPAQRQCLSPEEM 1081
Query: 1122 DFLECQNSPA 1131
D ECQ+ A
Sbjct: 1082 DVDECQDPAA 1091
Score = 200 bits (508), Expect = 8e-51
Identities = 124/338 (36%), Positives = 159/338 (47%), Gaps = 67/338 (19%)
Query: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 869
+ DEC + + C G C + C C G+ P+ CVD+NEC + EPC
Sbjct: 574 ETDECRLNQNICGHGE-CVPGPPDYSCH----CNPGYRSHPQHRYCVDVNECEA--EPCG 626
Query: 870 PGFS-CINTVGSYTCQRNPLICARGY--HASDDGTKCVDVNECETGVHRCGEGQVCHNLP 926
PG C+NT GSY C C RGY H G CVD+NEC H CG+G C N P
Sbjct: 627 PGRGICMNTGGSYNCH-----CNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFP 680
Query: 927 GSYRCDCKAGFQ------------------------------------------RDAFGR 944
G Y+C+C G++ R G
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 945 GCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE- 1002
C DVNEC + G C CEN GS+RC+CA G+ A DG+ C DV+ECEA
Sbjct: 741 ACRDVNEC--AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 1003 -CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1061
C+N GS+QC C GY L+ D C DIDEC A + C+N GSY+C CP QG+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCP-QGH 856
Query: 1062 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+ GR C+D+DEC+ C C N+QGS+ C+
Sbjct: 857 RL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Score = 139 bits (350), Expect = 2e-32
Identities = 201/842 (23%), Positives = 289/842 (34%), Gaps = 203/842 (24%)
Query: 377 PRDPVKPSPHNILSTSLPDA-AWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPE 435
P P KP LP++ + PP + + V S V E+ H ++P
Sbjct: 484 PDGPPKPQ-------QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPA 536
Query: 436 GSTKDLIETCCAAGQQWAIDN----DECLEI-PESGTEDNVCRTAQRHC----CVSYLQE 486
+LI +W + + +EI P TE + CR Q C CV +
Sbjct: 537 RPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPD 596
Query: 487 KSCMAGV-------------LGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
SC + E E CG C G L V A G+
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 656
Query: 534 SCE-----SNPNL----GYPCN---HVMLSCCEG-----EEPLIVPEVRRPPEPAAAPRR 576
SC + P+L G+ N H +C G P + ++ +P++ P
Sbjct: 657 SCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 577 VSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGF 635
E + + ++ D +EC G C C N GS+ C C G+
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGY 774
Query: 636 SLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC---------KDN 686
+ DGR+C + E V N I P C +D
Sbjct: 775 APAPDGRSCLDVD-------------ECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDR 821
Query: 687 GPCKQV-------------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRR 733
C+ + C GS C C G+ ++ G C+D DEC C
Sbjct: 822 SHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPH 880
Query: 734 QFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINE----------------CVTDLHT 776
C N GS+ CV C +G+ + C ++ + C + L T
Sbjct: 881 GACKNLQGSYVCV-----CDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 935
Query: 777 CSRGEHCVNTLGS--------FHCYKALTCEPGYALKDGEC---------------EDVD 813
+ C +LG+ + C + E DG+ D+D
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Query: 814 ECAM-GTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN---CVDINECTSLSEPCR 869
EC + G+ C+ G C NT+ + C C GF D GN CVD++EC S CR
Sbjct: 996 ECMLFGSEICKEG-KCVNTQPGYECY----CKQGFYYD--GNLLECVDVDECLDESN-CR 1047
Query: 870 PGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSY 929
G C NT G Y C P + +DV+EC+ C G+ C NLPGSY
Sbjct: 1048 NGV-CENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA-ACRPGR-CVNLPGSY 1104
Query: 930 RCDCKAGFQRDAFGRGCI-------------DVNECWASPGR--LCQHTCENTLGSYR-C 973
RC+C+ + GR C DV CW+ G +C ++ C
Sbjct: 1105 RCECRPPWVPGPSGRDCQLPESPAERAPERRDV--CWSQRGEDGMCAGPLAGPALTFDDC 1162
Query: 974 SCASGF---------------------------------LLAADGKRCEDVNECEAQRC- 999
C G LL R ED +E ++ C
Sbjct: 1163 CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR 1222
Query: 1000 --SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQ--GAGILC-TFRCLNVPGSYQC 1054
S C G C C G+QL C DIDEC + G+LC + RC+N GS++C
Sbjct: 1223 CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC 1282
Query: 1055 AC 1056
C
Sbjct: 1283 VC 1284
Score = 137 bits (344), Expect = 8e-32
Identities = 85/233 (36%), Positives = 114/233 (48%), Gaps = 18/233 (7%)
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
T+ + +EC + CG G+ C P Y C C G++ R C+DVNEC A P
Sbjct: 570 TQVTETDECRLNQNICGHGE-CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPG 628
Query: 961 QHTCENTLGSYRCSCASGFLL--AADGKRCEDVNECEAQRCSQE---CANIYGSYQCYCR 1015
+ C NT GSY C C G+ L A G+ C D+NEC + C N G Y+C C
Sbjct: 629 RGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCY 688
Query: 1016 QGYQL-AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
GY+L A C DIDEC + +C N PGS++C + GY + G +C+DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGY-RSQGGGACRDVN 746
Query: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
ECA G+ CS C N+ GSFRC C Y + +C D EC+
Sbjct: 747 ECAEGS-PCSPG-WCENLPGSFRC---TCAQGYAPAP----DGRSCLDVDECE 790
Score = 119 bits (297), Expect = 2e-26
Identities = 125/445 (28%), Positives = 171/445 (38%), Gaps = 91/445 (20%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC P H C N GSY C C GF+ D C QP +E L
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCE---EVEQPHHKKECYLN 922
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCFPGYA--- 709
+ + + + + Q C G PC V S+ ++C GY
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP-VYSSAEFHSLCPDGKGYTQDN 981
Query: 710 -IMADGVSCE-DQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDI 767
I+ G+ D DEC++ + + CVNT + C DG +L +CVD+
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLL----ECVDV 1037
Query: 768 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC-----EDVDECAMGTHTC 822
+EC+ D C G C NT G + C A T Y+ +C DVDEC C
Sbjct: 1038 DECL-DESNCRNGV-CENTRGGYRC--ACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAAC 1092
Query: 823 QPGFLCQNTKGSFYCQAR-------------------------------QRCMDGFLQDP 851
+PG C N GS+ C+ R QR DG P
Sbjct: 1093 RPG-RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGP 1151
Query: 852 -EGNCVDINECT--------SLSEPCRP---GFSCINTVGSYTC--QRNPLICARGYHAS 897
G + ++C + PC P G C + +PL+ G
Sbjct: 1152 LAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLL--GKPPR 1209
Query: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC--WAS 955
D+ + D +EC RC G+ C PG C+C GFQ DA C+D++EC
Sbjct: 1210 DEDSSEEDSDEC-----RCVSGR-CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQ 1263
Query: 956 PGRLCQ-HTCENTLGSYRCSCASGF 979
G LC+ C NT GS+RC C +GF
Sbjct: 1264 RGLLCKSERCVNTSGSFRCVCKAGF 1288
Score = 54.3 bits (129), Expect = 7e-07
Identities = 47/147 (31%), Positives = 59/147 (40%), Gaps = 24/147 (16%)
Query: 890 CARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI- 947
C +GY + T C D+NEC GV R G+ C N PGSYRC C G CI
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQCIA 396
Query: 948 ----DVNECW--ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ 1001
+ + C+ SP CQH L C C+ G A G RC QRC
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG---KAWGARC--------QRCPT 445
Query: 1002 ECANIYGSYQCYCRQGYQLAEDGHTCT 1028
+ + C +GY + T T
Sbjct: 446 DGTAAFKEI-CPAGKGYHILTSHQTLT 471
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 876 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH-NLPGSYR---- 930
+T+ C NPL G +D + ++ H+C + Q PG R
Sbjct: 282 DTLPKQPCGSNPL---PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVG 338
Query: 931 CDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRC 988
DC G++R C D+NEC A PG +C+H C N GSYRC C G L +C
Sbjct: 339 ADCPQGYKR-LNSTHCQDINEC-AMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 1001 QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQG 1060
Q+ + G C QGY+ H C DI+ECA G+ CLN PGSY+C CP G
Sbjct: 328 QKPGPVRGEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCP-PG 384
Query: 1061 YTMTANGRSC 1070
+++ + C
Sbjct: 385 HSLGPSRTQC 394
Score = 38.1 bits (87), Expect = 0.052
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1048 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
V G CP QGY N C+D++ECA+ C + C N GS+RC+ CPP +
Sbjct: 333 VRGEVGADCP-QGYKRL-NSTHCQDINECAM-PGVCRHGD-CLNNPGSYRCV---CPPGH 385
Query: 1108 -VQVSKTKC 1115
+ S+T+C
Sbjct: 386 SLGPSRTQC 394
Score = 36.6 bits (83), Expect = 0.15
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 598 NSLPGDDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTC 644
NS D +EC + PG +C+H C+N GSY C C PG SL C
Sbjct: 349 NSTHCQDINECAM-PG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 35.8 bits (81), Expect = 0.26
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 752 CADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL 804
C GY C DINEC C G+ C+N GS+ C C PG++L
Sbjct: 341 CPQGYKRLNSTHCQDINECAMP-GVCRHGD-CLNNPGSYRC----VCPPGHSL 387
Score = 34.3 bits (77), Expect = 0.75
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 604 DQDECLLLP--GELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE 647
D DEC L G LC+ C+NT GS+ C C GF+ C P+
Sbjct: 1254 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1300
Score = 31.2 bits (69), Expect = 6.4
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 798 CEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYC 837
C GY L C+D++ECAM C+ G C N GS+ C
Sbjct: 341 CPQGYKRLNSTHCQDINECAM-PGVCRHGD-CLNNPGSYRC 379
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 200 bits (508), Expect = 8e-51
Identities = 124/338 (36%), Positives = 159/338 (47%), Gaps = 67/338 (19%)
Query: 811 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 869
+ DEC + + C G C + C C G+ P+ CVD+NEC + EPC
Sbjct: 574 ETDECRLNQNICGHGE-CVPGPPDYSCH----CNPGYRSHPQHRYCVDVNECEA--EPCG 626
Query: 870 PGFS-CINTVGSYTCQRNPLICARGY--HASDDGTKCVDVNECETGVHRCGEGQVCHNLP 926
PG C+NT GSY C C RGY H G CVD+NEC H CG+G C N P
Sbjct: 627 PGRGICMNTGGSYNCH-----CNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFP 680
Query: 927 GSYRCDCKAGFQ------------------------------------------RDAFGR 944
G Y+C+C G++ R G
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 945 GCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE- 1002
C DVNEC + G C CEN GS+RC+CA G+ A DG+ C DV+ECEA
Sbjct: 741 ACRDVNEC--AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 1003 -CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1061
C+N GS+QC C GY L+ D C DIDEC A + C+N GSY+C CP QG+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCP-QGH 856
Query: 1062 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1099
+ GR C+D+DEC+ C C N+QGS+ C+
Sbjct: 857 RL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Score = 197 bits (502), Expect = 4e-50
Identities = 168/517 (32%), Positives = 214/517 (41%), Gaps = 94/517 (18%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ--DDGRTCRPEGHPPQPEAPQEPAL 661
D +EC P + +C+NT GSY+C C G+ L GR+C
Sbjct: 616 DVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC----------------- 658
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVS-CEDQ 720
+ ++ A +P+ C D G C G C+C+PGY + A CED
Sbjct: 659 -VDLNECA---------KPHLCGDGG----FCINFPGHYKCNCYPGYRLKASRPPVCEDI 704
Query: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
DEC C + C N GSF C+ C GY C D+NEC CS G
Sbjct: 705 DEC-RDPSSCPDGK-CENKPGSFKCI----ACQPGYRSQGGGACRDVNECAEG-SPCSPG 757
Query: 781 EHCVNTLGSFHCYKALTCEPGYA-LKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
C N GSF C TC GYA DG C DVDEC G C G +C NT GSF CQ
Sbjct: 758 -WCENLPGSFRC----TCAQGYAPAPDGRSCLDVDECEAGD-VCDNG-ICSNTPGSFQCQ 810
Query: 839 ARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
C+ G+ L +C DI+EC C G CINT GSY C +C +G H
Sbjct: 811 ----CLSGYHLSRDRSHCEDIDEC-DFPAACIGG-DCINTNGSYRC-----LCPQG-HRL 858
Query: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV------NE 951
G KC D++EC C C NL GSY C C GF GC +V E
Sbjct: 859 VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKE 918
Query: 952 CWAS--PGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGS 1009
C+ + C + C C+ G A G CE + C ++
Sbjct: 919 CYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWGDHCE-IYPCPVYSSAE-------- 966
Query: 1010 YQCYCRQGYQLAEDGHTCT-------DIDECAQ-GAGILCTFRCLNVPGSYQCACPEQGY 1061
+ C G +D + DIDEC G+ I +C+N Y+C C +QG+
Sbjct: 967 FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYC-KQGF 1025
Query: 1062 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
N C DVDEC L NC C N +G +RC
Sbjct: 1026 YYDGNLLECVDVDEC-LDESNCRNG-VCENTRGGYRC 1060
Score = 177 bits (448), Expect = 7e-44
Identities = 170/596 (28%), Positives = 229/596 (38%), Gaps = 151/596 (25%)
Query: 620 CINTVGSYHCACFPGFSLQ-------DDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNT 672
CIN G Y C C+PG+ L+ +D CR P + +P F +A
Sbjct: 676 CINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPG---SFKCIACQ- 731
Query: 673 IPLPLPQP-------NTCKDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDQDECL 724
P Q N C + PC C + GS C+C GYA DG SC D DEC
Sbjct: 732 -PGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECE 790
Query: 725 MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHC 783
G D C NT GSF C C GY L+ R C DI+EC D G C
Sbjct: 791 AG--DVCDNGICSNTPGSFQCQ-----CLSGYHLSRDRSHCEDIDEC--DFPAACIGGDC 841
Query: 784 VNTLGSFHCYKALTCEPGYALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
+NT GS+ C C G+ L G +C+D+DEC+ C P C+N +GS+ C
Sbjct: 842 INTNGSYRCL----CPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV---- 893
Query: 843 CMDGFL--QDPEGNCVDINE----------------CTSLSEPCRPGFSCINTVGS---- 880
C +GF QD G C ++ + C S+ C ++G+
Sbjct: 894 CDEGFTPTQDQHG-CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGD 952
Query: 881 ----YTCQRNPLICARGYHA-SDDGTKCV--------------DVNECET-GVHRCGEGQ 920
Y C P+ + +H+ DG D++EC G C EG+
Sbjct: 953 HCEIYPC---PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGK 1009
Query: 921 VCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGF 979
+ PG Y C CK GF D C+DV+EC C++ CENT G YRC+C
Sbjct: 1010 CVNTQPG-YECYCKQGFYYDGNLLECVDVDECLDESN--CRNGVCENTRGGYRCACTPPA 1066
Query: 980 LLAADGKRCEDVNE----------CEAQR-----CSQECANIYGSYQ-CYCRQGYQLAED 1023
+ ++C E C +QR C+ A ++ C CRQG
Sbjct: 1067 EYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQ 1126
Query: 1024 GHTCT--------------------------------------DIDECAQGAGILCTFRC 1045
C D DEC +G RC
Sbjct: 1127 CRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSG-----RC 1181
Query: 1046 LNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN--CSEAETCHNIQGSFRCL 1099
+ PG C CP G+ + A+ C D+DEC ++E C N GSFRC+
Sbjct: 1182 VPRPGGAVCECPG-GFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1236
Score = 137 bits (344), Expect = 8e-32
Identities = 85/233 (36%), Positives = 114/233 (48%), Gaps = 18/233 (7%)
Query: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
T+ + +EC + CG G+ C P Y C C G++ R C+DVNEC A P
Sbjct: 570 TQVTETDECRLNQNICGHGE-CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPG 628
Query: 961 QHTCENTLGSYRCSCASGFLL--AADGKRCEDVNECEAQRCSQE---CANIYGSYQCYCR 1015
+ C NT GSY C C G+ L A G+ C D+NEC + C N G Y+C C
Sbjct: 629 RGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCY 688
Query: 1016 QGYQL-AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVD 1074
GY+L A C DIDEC + +C N PGS++C + GY + G +C+DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGSFKCIACQPGY-RSQGGGACRDVN 746
Query: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
ECA G+ CS C N+ GSFRC C Y + +C D EC+
Sbjct: 747 ECAEGS-PCSPG-WCENLPGSFRC---TCAQGYAPAP----DGRSCLDVDECE 790
Score = 119 bits (297), Expect = 2e-26
Identities = 189/784 (24%), Positives = 271/784 (34%), Gaps = 207/784 (26%)
Query: 377 PRDPVKPSPHNILSTSLPDA-AWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPE 435
P P KP LP++ + PP + + V S V E+ H ++P
Sbjct: 484 PDGPPKPQ-------QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPA 536
Query: 436 GSTKDLIETCCAAGQQWAIDN----DECLEI-PESGTEDNVCRTAQRHC----CVSYLQE 486
+LI +W + + +EI P TE + CR Q C CV +
Sbjct: 537 RPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPD 596
Query: 487 KSCMAGV-------------LGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
SC + E E CG C G L V A G+
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 656
Query: 534 SCE-----SNPNL----GYPCN---HVMLSCCEG-----EEPLIVPEVRRPPEPAAAPRR 576
SC + P+L G+ N H +C G P + ++ +P++ P
Sbjct: 657 SCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 577 VSEA--------------------------EMAGREALSLGTEAELPNSL---------P 601
E E A S G LP S P
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAP 776
Query: 602 GDDQDECLLLP----GELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAP 656
D CL + G++C + +C NT GS+ C C G+ L D C P A
Sbjct: 777 APDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAAC 836
Query: 657 -QEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAICSCFP 706
+ + S L C+D C Q C + GS +C C
Sbjct: 837 IGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDE 896
Query: 707 GYAIMADGVSCEDQD------ECLMGAHD---CSR-------RQFCVNTLGS-------- 742
G+ D CE+ + EC + D C +Q C +LG+
Sbjct: 897 GFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEI 956
Query: 743 -----FYCVNHTVLCADG-----------YILNAHRKCVDINECVT-DLHTCSRGEHCVN 785
+ LC DG Y + AHR DI+EC+ C G+ CVN
Sbjct: 957 YPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHR---DIDECMLFGSEICKEGK-CVN 1012
Query: 786 TLGSFHCYKALTCEPGYALKDG---ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ---- 838
T + CY C+ G+ DG EC DVDEC + C+ G +C+NT+G + C
Sbjct: 1013 TQPGYECY----CKQGFYY-DGNLLECVDVDEC-LDESNCRNG-VCENTRGGYRCACTPP 1065
Query: 839 -----ARQRCM---------------------DGFLQDP-EGNCVDINECT--------S 863
A+++C+ DG P G + ++C +
Sbjct: 1066 AEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGA 1125
Query: 864 LSEPCRP---GFSCINTVGSYTC--QRNPLICARGYHASDDGTKCVDVNECETGVHRCGE 918
PC P G C + +PL+ G D+ + D +EC RC
Sbjct: 1126 QCRPCPPRGAGSHCPTSQSESNSFWDTSPLLL--GKPPRDEDSSEEDSDEC-----RCVS 1178
Query: 919 GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC--WASPGRLCQ-HTCENTLGSYRCSC 975
G+ C PG C+C GFQ DA C+D++EC G LC+ C NT GS+RC C
Sbjct: 1179 GR-CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVC 1237
Query: 976 ASGF 979
+GF
Sbjct: 1238 KAGF 1241
Score = 86.7 bits (213), Expect = 1e-16
Identities = 102/413 (24%), Positives = 145/413 (35%), Gaps = 96/413 (23%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC P H C N GSY C C GF+ D C QP +E L
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCE---EVEQPHHKKECYLN 922
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCFPGYA--- 709
+ + + + + Q C G PC V S+ ++C GY
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP-VYSSAEFHSLCPDGKGYTQDN 981
Query: 710 -IMADGVSCE-DQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDI 767
I+ G+ D DEC++ + + CVNT + C DG +L +CVD+
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLL----ECVDV 1037
Query: 768 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE------------- 814
+EC+ D C G C NT G + C A T Y+ +C +E
Sbjct: 1038 DECL-DESNCRNGV-CENTRGGYRC--ACTPPAEYSPAQRQCLSPEEMERAPERRDVCWS 1093
Query: 815 -----------------------CAMGTH---TCQPGFLCQNTKGSFYCQARQRCMDGFL 848
C G C+P C +C Q + F
Sbjct: 1094 QRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRP---CPPRGAGSHCPTSQSESNSFW 1150
Query: 849 -----------QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
+D + + D +EC +S C P G C+ C G+
Sbjct: 1151 DTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVP------RPGGAVCE-----CPGGFQLD 1199
Query: 898 DDGTKCVDVNECETGVHR---CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 947
+CVD++EC R C + + C N GS+RC CKAGF R C+
Sbjct: 1200 ASRARCVDIDECRELNQRGLLC-KSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 54.3 bits (129), Expect = 7e-07
Identities = 47/147 (31%), Positives = 59/147 (40%), Gaps = 24/147 (16%)
Query: 890 CARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI- 947
C +GY + T C D+NEC GV R G+ C N PGSYRC C G CI
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQCIA 396
Query: 948 ----DVNECW--ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ 1001
+ + C+ SP CQH L C C+ G A G RC QRC
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG---KAWGARC--------QRCPT 445
Query: 1002 ECANIYGSYQCYCRQGYQLAEDGHTCT 1028
+ + C +GY + T T
Sbjct: 446 DGTAAFKEI-CPAGKGYHILTSHQTLT 471
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 876 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH-NLPGSYR---- 930
+T+ C NPL G +D + ++ H+C + Q PG R
Sbjct: 282 DTLPKQPCGSNPL---PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVG 338
Query: 931 CDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRC 988
DC G++R C D+NEC A PG +C+H C N GSYRC C G L +C
Sbjct: 339 ADCPQGYKR-LNSTHCQDINEC-AMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 1001 QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQG 1060
Q+ + G C QGY+ H C DI+ECA G+ CLN PGSY+C CP G
Sbjct: 328 QKPGPVRGEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCP-PG 384
Query: 1061 YTMTANGRSC 1070
+++ + C
Sbjct: 385 HSLGPSRTQC 394
Score = 38.1 bits (87), Expect = 0.052
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1048 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
V G CP QGY N C+D++ECA+ C + C N GS+RC+ CPP +
Sbjct: 333 VRGEVGADCP-QGYKRL-NSTHCQDINECAM-PGVCRHGD-CLNNPGSYRCV---CPPGH 385
Query: 1108 -VQVSKTKC 1115
+ S+T+C
Sbjct: 386 SLGPSRTQC 394
Score = 36.6 bits (83), Expect = 0.15
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 598 NSLPGDDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTC 644
NS D +EC + PG +C+H C+N GSY C C PG SL C
Sbjct: 349 NSTHCQDINECAM-PG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 35.8 bits (81), Expect = 0.26
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 752 CADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL 804
C GY C DINEC C G+ C+N GS+ C C PG++L
Sbjct: 341 CPQGYKRLNSTHCQDINECAMP-GVCRHGD-CLNNPGSYRC----VCPPGHSL 387
Score = 35.8 bits (81), Expect = 0.26
Identities = 58/227 (25%), Positives = 75/227 (33%), Gaps = 41/227 (18%)
Query: 454 IDNDECLEIPESGTEDNVC---RTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC 510
+D DECL+ ES + VC R R C + L +E E E D C
Sbjct: 1035 VDVDECLD--ESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERA-PERRDVC 1091
Query: 511 ---------------GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG 555
G +L C CC G R G C P G +H S E
Sbjct: 1092 WSQRGEDGMCAGPLAGPALTFDDC-CCRQG---RGWGAQCRPCPPRGAG-SHCPTSQSES 1146
Query: 556 EE-----PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD------- 603
PL++ + R + + G E P D
Sbjct: 1147 NSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCV 1206
Query: 604 DQDECLLLP--GELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE 647
D DEC L G LC+ C+NT GS+ C C GF+ C P+
Sbjct: 1207 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1253
Score = 31.2 bits (69), Expect = 6.4
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 798 CEPGYA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYC 837
C GY L C+D++ECAM C+ G C N GS+ C
Sbjct: 341 CPQGYKRLNSTHCQDINECAM-PGVCRHGD-CLNNPGSYRC 379
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 185 bits (469), Expect = 3e-46
Identities = 171/594 (28%), Positives = 246/594 (41%), Gaps = 158/594 (26%)
Query: 604 DQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
D DEC + GE C+H C+NT GS+ C C G++ G C P P +
Sbjct: 158 DVDECRV--GEPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAPSPCRNGGT 211
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDN-GPCKQVCSTVGGSAI-------CSCFPGYAIMAD 713
+ + + LP + C+ N C GG+ + C C P +
Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWT---- 267
Query: 714 GVSC-EDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVT 772
G C ED DEC + + C C NTLG CV C +G+ +I++C T
Sbjct: 268 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV-----CVNGW--TGESCSQNIDDCAT 320
Query: 773 DLHTCSRGEHCVNTLGSFHCYKAL-----------------------------------T 797
+ C G C + + SF+C + T
Sbjct: 321 AV--CFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICT 378
Query: 798 CEPGYALKDGEC-EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNC- 855
C PG+ G C +DVDEC++G + C+ C NT+GSF CQ C G+ C
Sbjct: 379 CPPGFT--GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQ----CGRGYTGP---RCE 429
Query: 856 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC-VDVNECETGVH 914
D+NEC LS PCR +C++ +G +TC IC G+ GT C VD++EC++
Sbjct: 430 TDVNEC--LSGPCRNQATCLDRIGQFTC-----ICMAGF----TGTYCEVDIDECQSS-- 476
Query: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNECWASP----------------- 956
C G VC + + C C +GF G C +DV+EC ++P
Sbjct: 477 PCVNGGVCKDRVNGFSCTCPSGFS----GSTCQLDVDECASTPCRNGAKCVDQPDGYECR 532
Query: 957 ------GRLCQHT-------------CENTLGSYRCSCASGFLLAADGKRCE-DVNECEA 996
G LC C + + S+ C+CA G+ G RCE V+EC +
Sbjct: 533 CAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY----TGTRCESQVDECRS 588
Query: 997 QRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTC-TDIDECAQGAGILCTFR-CLNVPGSY 1052
Q C +C ++ Y C C G G C +ID+CA CTF C + Y
Sbjct: 589 QPCRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNP---CTFGVCRDGINRY 641
Query: 1053 QCACPEQGYTMTANGRSCK-DVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1105
C C + G+T G C +++ECA + C E +C + + FRCL CPP
Sbjct: 642 DCVC-QPGFT----GPLCNVEINECA--SSPCGEGGSCVDGENGFRCL---CPP 685
Score = 143 bits (360), Expect = 1e-33
Identities = 152/540 (28%), Positives = 217/540 (40%), Gaps = 154/540 (28%)
Query: 680 PNTCKDNGPCKQVCSTVG--GSAICSCFPGYAIMADGVSCE-DQDECLMGAHDCSRRQFC 736
P+ C + +VG G +CSC PGY G SC D DEC +G C C
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVG-EPCRHGGTC 174
Query: 737 VNTLGSF-----------YCVNHTVLCADGYILNA--------------------HRKC- 764
+NT GSF C N V CA N + C
Sbjct: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234
Query: 765 VDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTC 822
V++++C H C G CV+ + +++C C P + G+ EDVDEC + + C
Sbjct: 235 VNVDDCPG--HRCLNGGTCVDGVNTYNC----QCPPEWT---GQFCTEDVDECQLQPNAC 285
Query: 823 QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSY- 881
G C NT G C C++G+ E +I++C + C G +C + V S+
Sbjct: 286 HNGGTCFNTLGGHSCV----CVNGW--TGESCSQNIDDCA--TAVCFHGATCHDRVASFY 337
Query: 882 ---------------------------TCQRNPL------ICARGYHASDDGTKCVDVNE 908
C NP+ C G+ G DV+E
Sbjct: 338 CACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF---TGGACDQDVDE 394
Query: 909 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNECWASPGRLCQHTCENT 967
C G + C C N GS+ C C G+ G C DVNEC + P R Q TC +
Sbjct: 395 CSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSGPCR-NQATCLDR 449
Query: 968 LGSYRCSCASGFLLAADGKRCE-DVNECEAQRC--SQECANIYGSYQCYCRQGYQLAEDG 1024
+G + C C +GF G CE D++EC++ C C + + C C G+ G
Sbjct: 450 IGQFTCICMAGF----TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SG 501
Query: 1025 HTC-TDIDECA-----QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC-KDVDECA 1077
TC D+DECA GA +C++ P Y+C C E G+ G C ++VD+C+
Sbjct: 502 STCQLDVDECASTPCRNGA------KCVDQPDGYECRCAE-GF----EGTLCDRNVDDCS 550
Query: 1078 LGTHNCSEAETCHN---IQG--SFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPAR 1132
+ CH+ + G SF C C P Y + T+CE EC++ P R
Sbjct: 551 --------PDPCHHGRCVDGIASFSC---ACAPGY---TGTRCESQVD----ECRSQPCR 592
Score = 120 bits (302), Expect = 6e-27
Identities = 139/530 (26%), Positives = 195/530 (36%), Gaps = 137/530 (25%)
Query: 642 RTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAI 701
R RP PP P P AL P + C + G C Q+ S A
Sbjct: 10 RRRRPMSPPPPP--PPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSR---EAA 64
Query: 702 CSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAH 761
C C PG+ G C+ +D C G C+ R C +++ + + C G+
Sbjct: 65 CLCPPGWV----GERCQLEDPCHSGP--CAGRGVCQSSVVAG-TARFSCRCPRGF---RG 114
Query: 762 RKCVDINECVTDLHTCSRGEHC-VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTH 820
C + C++ C+ G C V G F C +C PGY
Sbjct: 115 PDCSLPDPCLSS--PCAHGARCSVGPDGRFLC----SCPPGYQ----------------- 151
Query: 821 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGS 880
G C++ D++EC + EPCR G +C+NT GS
Sbjct: 152 ----GRSCRS--------------------------DVDECR-VGEPCRHGGTCLNTPGS 180
Query: 881 YTCQ----------RNPLI------CARGYHASDDGTKCVDV--------NECETGV--- 913
+ CQ NP + C G G D CE V
Sbjct: 181 FRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC 240
Query: 914 --HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI-DVNECWASPGRLCQH--TCENTL 968
HRC G C + +Y C C + G+ C DV+EC P C + TC NTL
Sbjct: 241 PGHRCLNGGTCVDGVNTYNCQCPPEWT----GQFCTEDVDECQLQP-NACHNGGTCFNTL 295
Query: 969 GSYRCSCASGFLLAADGKRC-EDVNECEAQRC--SQECANIYGSYQCYCRQGYQLAEDGH 1025
G + C C +G+ G+ C +++++C C C + S+ C C G + G
Sbjct: 296 GGHSCVCVNGW----TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG----KTGL 347
Query: 1026 TCTDIDECAQG---AGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN 1082
C D C +C +N G C CP G+T G +DVDEC++G +
Sbjct: 348 LCHLDDACVSNPCHEDAICDTNPVN--GRAICTCP-PGFT---GGACDQDVDECSIGANP 401
Query: 1083 CSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPAR 1132
C C N QGSF C +C Y + +CE D EC + P R
Sbjct: 402 CEHLGRCVNTQGSFLC---QCGRGY---TGPRCET----DVNECLSGPCR 441
Score = 116 bits (291), Expect = 1e-25
Identities = 143/547 (26%), Positives = 208/547 (38%), Gaps = 94/547 (17%)
Query: 606 DECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPE-----GHPPQPEAPQEP 659
D+C P C H C++ + S+ CAC PG++ G C + P +
Sbjct: 547 DDCSPDP---CHHGRCVDGIASFSCACAPGYT----GTRCESQVDECRSQPCRHGGKCLD 599
Query: 660 ALKSEFSQVASNTIPLPLP-QPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCE 718
+ + S T + + C N VC C C PG+ G C
Sbjct: 600 LVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFT----GPLCN 655
Query: 719 DQ-DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTC 777
+ +EC + C CV+ F C LC G + C+ H C
Sbjct: 656 VEINEC--ASSPCGEGGSCVDGENGFRC-----LCPPGSLPPL---------CLPPSHPC 699
Query: 778 SRG--EH--CVNTLGSFHCYKALTCEPGYALKDGEC-EDVDECAMGTHTCQPGFLCQNTK 832
+ H C + G F C CEPG++ C + + A + C+ G C +
Sbjct: 700 AHEPCSHGICYDAPGGFRC----VCEPGWS--GPRCSQSLARDACESQPCRAGGTCSSDG 753
Query: 833 GSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICA 891
F+C C G +G C ++ CT PC G C + G Q C
Sbjct: 754 MGFHCT----CPPGV----QGRQCELLSPCTP--NPCEHGGRCESAPG----QLPVCSCP 799
Query: 892 RGYHASDDGTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDV 949
+G+ G +C DV+EC G CG +C NL GS+ C C G+ G C D+
Sbjct: 800 QGWQ----GPRCQQDVDEC-AGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCDQDI 850
Query: 950 NECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC-EDVNECEAQRCSQ-ECANIY 1007
N+C +P L +C++ +GS+ CSC GF G RC DV+EC + C C +
Sbjct: 851 NDCDPNP-CLNGGSCQDGVGSFSCSCLPGFA----GPRCARDVDECLSNPCGPGTCTDHV 905
Query: 1008 GSYQCYCRQGYQLAEDGHTC-TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTAN 1066
S+ C C GY G C D+ +C+ + C++ S+ C C GYT
Sbjct: 906 ASFTCTCPPGY----GGFHCEQDLPDCSP-SSCFNGGTCVDGVNSFSCLC-RPGYT---- 955
Query: 1067 GRSCK-DVDECALGTHNCSEAETCHNIQGSFRCLRFEC-PPNYVQVSKTKCERTTCHDFL 1124
G C+ + D C + C C FRC E Q C R C +
Sbjct: 956 GAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGG 1013
Query: 1125 ECQNSPA 1131
C + A
Sbjct: 1014 RCVQTGA 1020
Score = 114 bits (284), Expect = 7e-25
Identities = 181/719 (25%), Positives = 257/719 (35%), Gaps = 192/719 (26%)
Query: 519 CDCCGLGLRVRA----EGQSCES-NPNLGYPCNHV--------MLSCCEGEEPLIVPEVR 565
C G+G +G+ CE +P PC H L C + P +
Sbjct: 749 CSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ 808
Query: 566 RPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQD--EC---LLLPGELCQHLC 620
+ + A P + A S + P DQD +C L G CQ
Sbjct: 809 QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ--- 865
Query: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP------ 674
+ VGS+ C+C PGF+ G C + P P ++ + T P
Sbjct: 866 -DGVGSFSCSCLPGFA----GPRCARDVDECLSN-PCGPGTCTDHVASFTCTCPPGYGGF 919
Query: 675 -----LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDE------C 723
LP P++C + G C ++ C C PGY G C+ + + C
Sbjct: 920 HCEQDLPDCSPSSCFNGGTCVDGVNSFS----CLCRPGYT----GAHCQHEADPCLSRPC 971
Query: 724 LMG-----AHD---------------------CSRRQF-----CVNTLGSFYCVNHTVLC 752
L G AH CSR+ CV T YC LC
Sbjct: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYC-----LC 1024
Query: 753 ADGYILNAHRKC----VDINECVTDL-----HTCSRGEHCVNTLGSFHCYKALTCEPGYA 803
G+ + R C + E + C G CV+ S +C C G
Sbjct: 1025 PPGW---SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC----VCPEGRT 1077
Query: 804 LKDGECE-DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVD-INEC 861
CE +VD C CQ G C+ G + C+ C+ G+ D NC D ++EC
Sbjct: 1078 --GSHCEQEVDPCL--AQPCQHGGTCRGYMGGYMCE----CLPGYNGD---NCEDDVDEC 1126
Query: 862 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV-------H 914
S +PC+ G SCI+ V Y C P G C ++NE + G
Sbjct: 1127 AS--QPCQHGGSCIDLVARYLCSCPP---------GTLGVLC-EINEDDCGPGPPLDSGP 1174
Query: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNECWASPGRLCQHT---CENTLGS 970
RC C +L G +RC C G+ G C D+NEC S HT ++ G
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYT----GLRCEADINEC-RSGACHAAHTRDCLQDPGGG 1229
Query: 971 YRCSCASGFLLAADGKRCEDV-NECEAQRCSQ--ECANIYG-----SYQCYCRQ---GYQ 1019
+RC C +GF G RC+ V + CE+Q C +C G ++ C+C Q G +
Sbjct: 1230 FRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPR 1285
Query: 1020 LAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1079
+C ++ +C G C P +CACP +G SC+ G
Sbjct: 1286 CERVARSCREL-QCPVGV------PCQQTPRGPRCACPP-----GLSGPSCRSFPGSPPG 1333
Query: 1080 THN--CSEAETCHN-------IQGSFRCL--------RFECPPNYVQVS-KTKCERTTC 1120
N C+ A H + FRC R E P +VS + +C R C
Sbjct: 1334 ASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAAC 1392
Score = 72.8 bits (177), Expect = 2e-12
Identities = 77/298 (25%), Positives = 110/298 (36%), Gaps = 68/298 (22%)
Query: 916 CGEGQVCHNLPG-SYRCDCKAGFQRDAFGRGCIDVNECWASP--GR-LCQHTCENTLGSY 971
C G C LP C C G+ G C + C + P GR +CQ + +
Sbjct: 49 CANGGRCTQLPSREAACLCPPGW----VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARF 104
Query: 972 RCSCASGFLLAADGKRCEDVNECEAQRCSQ--ECA-NIYGSYQCYCRQGYQLAEDGHTC- 1027
C C GF G C + C + C+ C+ G + C C GYQ G +C
Sbjct: 105 SCRCPRGFR----GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSCR 156
Query: 1028 TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT--------------MTANGRSCK-- 1071
+D+DEC G CLN PGS++C CP GYT NG +C+
Sbjct: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCP-AGYTGPLCENPAVPCAPSPCRNGGTCRQS 215
Query: 1072 --------------------DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV--- 1108
+VD+C H C TC + ++ C +CPP +
Sbjct: 216 GDLTYDCACLPGFEGQNCEVNVDDCP--GHRCLNGGTCVDGVNTYNC---QCPPEWTGQF 270
Query: 1109 ---QVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDT 1163
V + + + CH+ C N+ + +N TG +I A F G T
Sbjct: 271 CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,257,660
Number of Sequences: 37866
Number of extensions: 3689704
Number of successful extensions: 34381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 691
Number of HSP's that attempted gapping in prelim test: 20471
Number of HSP's gapped (non-prelim): 6212
length of query: 1231
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1117
effective length of database: 13,930,794
effective search space: 15560696898
effective search space used: 15560696898
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.