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Search of human proteins with 5174463
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174463 heparan sulfate D-glucosaminyl 3-O-sulfotransferase
2 [Homo sapiens]
(367 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174463 heparan sulfate D-glucosaminyl 3-O-sulfotransferase ... 756 0.0
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase... 446 e-125
gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3... 434 e-122
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3... 420 e-118
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ... 404 e-113
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5... 246 3e-65
gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1... 233 3e-61
gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminy... 129 3e-30
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase... 128 9e-30
gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4 [... 127 2e-29
gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminy... 117 2e-26
gi|45505173 B cell RAG associated protein [Homo sapiens] 41 0.001
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 35 0.082
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 35 0.14
gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform... 35 0.14
gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform... 35 0.14
gi|16306552 semaphorin Y [Homo sapiens] 35 0.14
gi|239756116 PREDICTED: hypothetical protein [Homo sapiens] 34 0.18
gi|239744954 PREDICTED: hypothetical protein XP_002343343 [Homo ... 34 0.18
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 34 0.18
gi|239756307 PREDICTED: similar to ubiquitin-associated protein ... 33 0.31
gi|239750857 PREDICTED: similar to ubiquitin-associated protein ... 33 0.31
gi|239745220 PREDICTED: hypothetical protein [Homo sapiens] 33 0.31
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 33 0.31
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 33 0.31
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens] 33 0.41
gi|171543895 ataxin 2 [Homo sapiens] 33 0.41
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 33 0.41
gi|190886454 tumor specificity and mitosis phase-dependent expre... 33 0.41
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 33 0.41
>gi|5174463 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2
[Homo sapiens]
Length = 367
Score = 756 bits (1952), Expect = 0.0
Identities = 367/367 (100%), Positives = 367/367 (100%)
Query: 1 MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPS 60
MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPS
Sbjct: 1 MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPS 60
Query: 61 AGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIV 120
AGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIV
Sbjct: 61 AGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIV 120
Query: 121 GVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPS 180
GVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPS
Sbjct: 121 GVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPS 180
Query: 181 YFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGL 240
YFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGL
Sbjct: 181 YFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGL 240
Query: 241 VDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITD 300
VDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITD
Sbjct: 241 VDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITD 300
Query: 301 KHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETV 360
KHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETV
Sbjct: 301 KHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETV 360
Query: 361 GQDFRWE 367
GQDFRWE
Sbjct: 361 GQDFRWE 367
>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
[Homo sapiens]
Length = 456
Score = 446 bits (1146), Expect = e-125
Identities = 241/432 (55%), Positives = 288/432 (66%), Gaps = 84/432 (19%)
Query: 10 GPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLR-GPSAGGQ---- 64
GPP AR+LLF TLSLS TYLCYS L G S L P L+ P A +
Sbjct: 29 GPP----ARKLLFMCTLSLSVTYLCYSLL------GGSGSLQFPLALQESPGAAAEPPPS 78
Query: 65 -----------KLLQKSRPCDPS-------GPTPSEPSAPSAPA---------------- 90
+L S+P P G P P P+AP
Sbjct: 79 PPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGGGGAQDA 138
Query: 91 ---------------AAVPAPRL----------------SGSNHSG----SPKLGTKRLP 115
+A+P +GS+ G +P G K+LP
Sbjct: 139 WLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRRAANGSSERGGAVSTPDYGEKKLP 198
Query: 116 QALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITL 175
QALI+GVKKGGTRA+LE IRVHPDVRA+G EPHFFDRNY +GL+WYR++MP+TL+ QIT+
Sbjct: 199 QALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITM 258
Query: 176 EKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRN 235
EKTPSYFVT EAP+RI +M++D KLIVVVRNPVTRAISDYTQTLSKKP+IPTFE L+F+N
Sbjct: 259 EKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKN 318
Query: 236 RTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIK 295
RTLGL+D SW+AIRIG+Y LHLE+WLQYFPL+QI FVSGERLI DPAGEM +VQDFLG+K
Sbjct: 319 RTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLK 378
Query: 296 RFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIK 355
R +T+KHFYFNKTKGFPCLKK E S PRCLGKSKGRTH +IDP+VI +LR+FY+P+N+
Sbjct: 379 RVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLM 438
Query: 356 FYETVGQDFRWE 367
FY+ GQDF+WE
Sbjct: 439 FYQMTGQDFQWE 450
>gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
[Homo sapiens]
Length = 390
Score = 434 bits (1115), Expect = e-122
Identities = 225/377 (59%), Positives = 274/377 (72%), Gaps = 16/377 (4%)
Query: 4 RVLGRAGPPQPRRARRLLFAFTLSLSCTYL-CYSFLCCCDDLGRSRLLGA--------PR 54
R+L + PP P R+L F + Y+ YS C LLG+ P
Sbjct: 17 RLLPQPPPPPPPVRRKLALLFAMLCVWLYMFLYSCAGSCAAAPGLLLLGSGSRAAHDPPA 76
Query: 55 CLRGPSAGGQKLLQKSRPCDP--SGPTPSEPSA-PSAPAAAVP-APRLSGSNHSGSPKLG 110
P +L ++ P P SG +E +A P + VP +P S SGS G
Sbjct: 77 LATAPDGTPPRLPFRAPPATPLASGKEMAEGAASPEEQSPEVPDSPSPISSFFSGS---G 133
Query: 111 TKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLE 170
+K+LPQA+I+GVKKGGTRA+LEF+RVHPDVRA+G EPHFFDR+Y +GL WYR LMPRTL+
Sbjct: 134 SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLD 193
Query: 171 SQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEG 230
QIT+EKTPSYFVT+EAP RI MS+DTKLIVVVR+PVTRAISDYTQTLSK+PDIPTFE
Sbjct: 194 GQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFES 253
Query: 231 LSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQD 290
L+F+NRT GL+D SW+AI+IG+Y HLE WL++FP+ Q+ FVSGERLI+DPAGE+GRVQD
Sbjct: 254 LTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQD 313
Query: 291 FLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYR 350
FLG+KR ITDKHFYFNKTKGFPCLKK E S P CLGK+KGRTH +ID EV+ +LREFYR
Sbjct: 314 FLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYR 373
Query: 351 PYNIKFYETVGQDFRWE 367
P+N+KFY+ G DF W+
Sbjct: 374 PFNLKFYQMTGHDFGWD 390
>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
[Homo sapiens]
Length = 406
Score = 420 bits (1080), Expect = e-118
Identities = 193/258 (74%), Positives = 229/258 (88%)
Query: 110 GTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTL 169
G+K+LPQA+I+GVKKGGTRA+LEF+RVHPDVRA+G EPHFFDR+Y +GL WYR LMPRTL
Sbjct: 148 GSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTL 207
Query: 170 ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFE 229
+ QIT+EKTPSYFVT+EAP RI MS+DTKLIVVVR+PVTRAISDYTQTLSK+PDIPTFE
Sbjct: 208 DGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFE 267
Query: 230 GLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQ 289
L+F+NRT GL+D SW+AI+IG+Y HLE WL++FP+ Q+ FVSGERLI+DPAGE+GRVQ
Sbjct: 268 SLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQ 327
Query: 290 DFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFY 349
DFLG+KR ITDKHFYFNKTKGFPCLKK E S P CLGK+KGRTH +ID EV+ +LREFY
Sbjct: 328 DFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFY 387
Query: 350 RPYNIKFYETVGQDFRWE 367
RP+N+KFY+ G DF W+
Sbjct: 388 RPFNLKFYQMTGHDFGWD 405
>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
[Homo sapiens]
Length = 311
Score = 404 bits (1037), Expect = e-113
Identities = 193/294 (65%), Positives = 233/294 (79%), Gaps = 3/294 (1%)
Query: 73 CDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTKRLPQALIVGVKKGGTRAVLE 132
C P+ P+ APS P+++V P G + P G +R PQALIVGVKKGGTRA+LE
Sbjct: 20 CPPAARAPAPAPAPSEPSSSVHRPGAPGLPLASGP--GRRRFPQALIVGVKKGGTRALLE 77
Query: 133 FIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIF 192
F+R+HPDVRALG+EPHFFDR Y RGL WYRSLMPRTL+ QIT+EKTPSYFVT+EAPRRI
Sbjct: 78 FLRLHPDVRALGSEPHFFDRCYERGLAWYRSLMPRTLDGQITMEKTPSYFVTREAPRRIH 137
Query: 193 NMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGM 252
MS DTKLIVVVRNPVTRAISDY QTLSK P +P+F L+FR+ LG VD +W+A+RIG+
Sbjct: 138 AMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGLPSFRALAFRH-GLGPVDTAWSAVRIGL 196
Query: 253 YVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFP 312
Y HL+ WL+YFPL+ FVSGERL++DPAGE+GRVQDFLG+KR +TDKHFYFN TKGFP
Sbjct: 197 YAQHLDHWLRYFPLSHFLFVSGERLVSDPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFP 256
Query: 313 CLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRW 366
CLKK + PRCLGKSKGR H ++ ++ +L+EFYRP+N +FY+ GQDF W
Sbjct: 257 CLKKAQGGSRPRCLGKSKGRPHPRVPQALVRRLQEFYRPFNRRFYQMTGQDFGW 310
>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
[Homo sapiens]
Length = 346
Score = 246 bits (627), Expect = 3e-65
Identities = 120/261 (45%), Positives = 170/261 (65%), Gaps = 9/261 (3%)
Query: 112 KRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDR--NYGRGLDWYRSLMPRTL 169
++LP+A+I+GV+KGGTRA+LE + +HP V E HFFD NYG+G++WYR MP +
Sbjct: 88 QQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYGKGIEWYRKKMPFSY 147
Query: 170 ESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLS----KKPDI 225
QIT+EK+P+YF+T+E P RI+ M+ KL+++VR P TRAISDYTQ L K
Sbjct: 148 PQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTY 207
Query: 226 PTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEM 285
FE L+ T V+ + A+R +Y HLE WL+YFP+ Q H V G+RLIT+P E+
Sbjct: 208 YKFEKLAIDPNTCE-VNTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLITEPLPEL 266
Query: 286 GRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQL 345
V+ FL + I+ + YFN T+GF CL+ + + +CL SKGR H ++DP VI +L
Sbjct: 267 QLVEKFLNLPPRISQYNLYFNATRGFYCLR--FNIIFNKCLAGSKGRIHPEVDPSVITKL 324
Query: 346 REFYRPYNIKFYETVGQDFRW 366
R+F+ P+N KFY+ G+ W
Sbjct: 325 RKFFHPFNQKFYQITGRTLNW 345
>gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
precursor [Homo sapiens]
Length = 307
Score = 233 bits (593), Expect = 3e-61
Identities = 120/294 (40%), Positives = 180/294 (61%), Gaps = 13/294 (4%)
Query: 80 PSEPSAPSAPAAAVPAPRLSGSNHSG-SPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHP 138
PS P+ A L G +P ++LPQ +I+GV+KGGTRA+LE + +HP
Sbjct: 19 PSRPAELGQQELLRKAGTLQDDVRDGVAPNGSAQQLPQTIIIGVRKGGTRALLEMLSLHP 78
Query: 139 DVRALGTEPHFFD--RNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSR 196
DV A E HFFD +Y GL WY S MP + Q+T+EKTP+YF + + P R+++M+
Sbjct: 79 DVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNP 138
Query: 197 DTKLIVVVRNPVTRAISDYTQT----LSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGM 252
+L++++R+P R +SDYTQ + K P+ E R+ G ++V + A+ +
Sbjct: 139 SIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRD---GRLNVDYKALNRSL 195
Query: 253 YVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFP 312
Y +H+++WL++FPL IH V G+RLI DP E+ +V+ FL + I +FYFNKTKGF
Sbjct: 196 YHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFY 255
Query: 313 CLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRW 366
CL+ S RCL +SKGR H Q+DP+++++L E++ N KF+E VG+ F W
Sbjct: 256 CLR---DSGRDRCLHESKGRAHPQVDPKLLNKLHEYFHEPNKKFFELVGRTFDW 306
>gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
3 [Homo sapiens]
Length = 873
Score = 129 bits (325), Expect = 3e-30
Identities = 85/258 (32%), Positives = 132/258 (51%), Gaps = 17/258 (6%)
Query: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSL- 164
RLP+ L++G +K GT A+ F+ +HP + + P FF+RN Y RG+DWY
Sbjct: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
Query: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223
+P + + EK+ +YF ++EAP+R ++ K+I ++ +P RA S Y S +
Sbjct: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHED 713
Query: 224 DIPT----FEGLSFRNRTLG-LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLI 278
+E +S R L + + G Y H+E WL YFP Q+ + G++L
Sbjct: 714 PAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLR 773
Query: 279 TDPAGEMGRVQDFLGI-KRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQI 337
TDPA M VQ FLG+ + + F+ KGF C E +CLGKSKGR + +
Sbjct: 774 TDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGK--TKCLGKSKGRKYPPM 831
Query: 338 DPEVIDQLREFYRPYNIK 355
D + L +YR +N++
Sbjct: 832 DSDSRTFLSSYYRDHNVE 849
>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
[Homo sapiens]
Length = 883
Score = 128 bits (321), Expect = 9e-30
Identities = 85/258 (32%), Positives = 129/258 (50%), Gaps = 17/258 (6%)
Query: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDR-------NYGRGLDWYRSL- 164
RLP+ LIVG +K GT A+ F+ +HP V + P F+ NY +G+DWY
Sbjct: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
Query: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223
+P + EK+ +YF ++ PRR + K+I V+ NP RA S Y +
Sbjct: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721
Query: 224 DIPT----FEGLSFRNRT-LGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLI 278
+ ++ +S ++T L L + + G Y HL+ WL Y+P Q+ V G+ L
Sbjct: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781
Query: 279 TDPAGEMGRVQDFLGIKRFIT-DKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQI 337
T+PA M +Q FLGI F+ + F+ KGF C RCLG+SKGR + +
Sbjct: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGK--TRCLGRSKGRRYPDM 839
Query: 338 DPEVIDQLREFYRPYNIK 355
D E L +F+R +N++
Sbjct: 840 DTESRLFLTDFFRNHNLE 857
>gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4
[Homo sapiens]
Length = 872
Score = 127 bits (318), Expect = 2e-29
Identities = 82/257 (31%), Positives = 130/257 (50%), Gaps = 17/257 (6%)
Query: 114 LPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDR-------NYGRGLDWYRSLMP 166
LP+ L++G +K GT A+ F+ +HP + + P F+ NY +G+DWY P
Sbjct: 594 LPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFP 653
Query: 167 R--TLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPD 224
S EK+ +YF ++EAPRR ++ K+I ++ +P RA S Y S +
Sbjct: 654 TPSNTTSDFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDP 713
Query: 225 IPT----FEGLSFRN-RTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLIT 279
+E +S + L + + G Y +H+E WL YF +Q+ + G++L +
Sbjct: 714 AALRFNFYEVISTGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRS 773
Query: 280 DPAGEMGRVQDFLGI-KRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQID 338
DPA M VQ FLG+ R+ + F+ KGF C + +CLGKSKGR + +D
Sbjct: 774 DPATVMDEVQKFLGVTPRYNYSEALTFDPQKGFWC--QLLEGGKTKCLGKSKGRKYPPMD 831
Query: 339 PEVIDQLREFYRPYNIK 355
PE L +YR +N++
Sbjct: 832 PESRTFLSNYYRDHNVE 848
>gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
1 [Homo sapiens]
Length = 882
Score = 117 bits (292), Expect = 2e-26
Identities = 84/260 (32%), Positives = 126/260 (48%), Gaps = 21/260 (8%)
Query: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRA------LGTEPHFFD-RNYGRGLDWYRSL- 164
R P+ LI+G +K GT A+ F+ +HPD+ + E FF+ NY +G+DWY
Sbjct: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
Query: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223
+P S EK+ +YF ++ APRR + K++ ++ NP RA S Y +
Sbjct: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQH--QRAH 720
Query: 224 DIPTFEGLSFRNRTLGLVDVSWNAIRI-------GMYVLHLESWLQYFPLAQIHFVSGER 276
D P +F D S + G Y H+E WL + QI + G+
Sbjct: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
Query: 277 LITDPAGEMGRVQDFLGIKRFIT-DKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHV 335
L T+PA M VQ FLG+ I K F+ KGF C + +CLGKSKGR +
Sbjct: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWC--QLLEGGKTKCLGKSKGRKYP 838
Query: 336 QIDPEVIDQLREFYRPYNIK 355
++D + L+++YR +NI+
Sbjct: 839 EMDLDSRAFLKDYYRDHNIE 858
>gi|45505173 B cell RAG associated protein [Homo sapiens]
Length = 561
Score = 41.2 bits (95), Expect = 0.001
Identities = 69/334 (20%), Positives = 119/334 (35%), Gaps = 85/334 (25%)
Query: 103 HSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVR-ALGTEPHFFDR-NYG----- 155
H+ + LP I+G K GT + + +R+HP+V+ + EPH++ R +G
Sbjct: 242 HAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLR 301
Query: 156 ------------------------RGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRI 191
+GL + + + I E + S A
Sbjct: 302 DGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFF 361
Query: 192 FNMSRD-----------------TKLIVVVRNPVTRAISDYTQTLSKKPDIPTF-----E 229
++ S D +LIV++R+PV R SDY S F E
Sbjct: 362 YDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTE 421
Query: 230 GLS-FRNRTLGLVDVSWNA--------------IRIGMYVLHLESWLQYFPLAQIHFVSG 274
L F N ++D S A +++G+Y ++L WL F Q +
Sbjct: 422 ALQLFEN---CMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRL 478
Query: 275 ERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTH 334
E ++ M +V FL + + K+ + + +L P
Sbjct: 479 EDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGP----------- 527
Query: 335 VQIDPEVIDQLREFYRPYNIKFYETVGQD-FRWE 367
+ P LR+FYRP+N + + + + F W+
Sbjct: 528 --MWPITQKILRDFYRPFNARLAQVLADEAFAWK 559
>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
Length = 193
Score = 35.4 bits (80), Expect = 0.082
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 48 RLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSP 107
RLL +R AGG + Q RP P GP + P A S P+ A +P GS+ GSP
Sbjct: 104 RLLAEHDAVRNALAGGLRP-QAVRPSAPRGPPGTTPVAAS-PSRASSSPGRGGSSEPGSP 161
Query: 108 K 108
+
Sbjct: 162 R 162
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 34.7 bits (78), Expect = 0.14
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 9/71 (12%)
Query: 50 LGAPRCLRGPSAGGQKLLQKSRPCDPSGP--TPSEPSAP-SAPAAAVPAPRLSGSNHSGS 106
LG+PR +R P G P P+ P P+ P AP ++P +PA L+G
Sbjct: 752 LGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAG------ 805
Query: 107 PKLGTKRLPQA 117
P L +RL +A
Sbjct: 806 PALPARRLSRA 816
>gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a
[Homo sapiens]
Length = 2436
Score = 34.7 bits (78), Expect = 0.14
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 45 GRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVP 94
G+ + G+P L+G G +L RP +P G P EP S+P P
Sbjct: 1198 GKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGG--PQEPGLASSPPGRAP 1245
>gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b
[Homo sapiens]
Length = 2466
Score = 34.7 bits (78), Expect = 0.14
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 45 GRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVP 94
G+ + G+P L+G G +L RP +P G P EP S+P P
Sbjct: 1228 GKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGG--PQEPGLASSPPGRAP 1275
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 34.7 bits (78), Expect = 0.14
Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 52 APRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGT 111
AP L GPS + R P P SAP+ PA + PAPRL P G
Sbjct: 800 APALLGGPSPRPHECASPLRLDVP--PEGRCASAPARPALSAPAPRLGVGGGRRLPFSG- 856
Query: 112 KRLPQALIVGVKKGG 126
R P AL+ V GG
Sbjct: 857 HRAPPALLTRVPSGG 871
>gi|239756116 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 34.3 bits (77), Expect = 0.18
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 43 DLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSN 102
D R L +PR L P+ L++ + +P P P E S P ++ +P +
Sbjct: 13 DSSRVSTLLSPRALSLPAEEPHARLREDKQGEP--PPPGEFSPPGDGSSTLPGGDPACLL 70
Query: 103 HSGSPKLGTKRLPQALIVGVKKGGTRAV 130
S SP LGT+ P A G G R V
Sbjct: 71 KSCSPGLGTRSSPAAAGGGATSGSPRVV 98
>gi|239744954 PREDICTED: hypothetical protein XP_002343343 [Homo
sapiens]
Length = 194
Score = 34.3 bits (77), Expect = 0.18
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 43 DLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSN 102
D R L +PR L P+ L++ + +P P P E S P ++ +P +
Sbjct: 13 DSSRVSTLLSPRALSLPAEEPHARLREDKQGEP--PPPGEFSPPGDGSSTLPGGDPACLL 70
Query: 103 HSGSPKLGTKRLPQALIVGVKKGGTRAV 130
S SP LGT+ P A G G R V
Sbjct: 71 KSCSPGLGTRSSPAAAGGGATSGSPRVV 98
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 34.3 bits (77), Expect = 0.18
Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
Query: 315 KKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREF---YRPYNIKFYETV 360
K ESS+LP+C+G +T + +D + LR YR + K YE +
Sbjct: 595 KGAESSILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEI 643
>gi|239756307 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 33.5 bits (75), Expect = 0.31
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 13/81 (16%)
Query: 44 LGRSRLLGAPRCLRGPSAGGQKL------LQKSRPCDPSGPTPSEPSAPSAPAAAVPAPR 97
L +L+ PR L G + L Q R P GP P P+AP++P P P
Sbjct: 162 LSEGKLVSRPRALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASP----PRPS 217
Query: 98 LSGS---NHSGSPKLGTKRLP 115
+G+ S P + + LP
Sbjct: 218 TAGAIPPLRSHKPTVAVRILP 238
>gi|239750857 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 33.5 bits (75), Expect = 0.31
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 13/81 (16%)
Query: 44 LGRSRLLGAPRCLRGPSAGGQKL------LQKSRPCDPSGPTPSEPSAPSAPAAAVPAPR 97
L +L+ PR L G + L Q R P GP P P+AP++P P P
Sbjct: 162 LSEGKLVSRPRALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASP----PRPS 217
Query: 98 LSGS---NHSGSPKLGTKRLP 115
+G+ S P + + LP
Sbjct: 218 TAGAIPPLRSHKPTVAVRILP 238
>gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 33.5 bits (75), Expect = 0.31
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 13/81 (16%)
Query: 44 LGRSRLLGAPRCLRGPSAGGQKL------LQKSRPCDPSGPTPSEPSAPSAPAAAVPAPR 97
L +L+ PR L G + L Q R P GP P P+AP++P P P
Sbjct: 162 LSEGKLVSRPRALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASP----PRPS 217
Query: 98 LSGS---NHSGSPKLGTKRLP 115
+G+ S P + + LP
Sbjct: 218 TAGAIPPLRSHKPTVAVRILP 238
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 33.5 bits (75), Expect = 0.31
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 58 GPSAGGQKLLQKSRPCDPSG-PTPSEPSAPSAPAAAVPAP 96
GP G QK P G P+P+ P+A PAAAVP P
Sbjct: 266 GPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGP 305
Score = 29.3 bits (64), Expect = 5.8
Identities = 14/40 (35%), Positives = 18/40 (45%)
Query: 50 LGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAP 89
LGAP + P +GG + P P P +P A S P
Sbjct: 128 LGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQP 167
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 33.5 bits (75), Expect = 0.31
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 58 GPSAGGQKLLQKSRPCDPSG-PTPSEPSAPSAPAAAVPAP 96
GP G QK P G P+P+ P+A PAAAVP P
Sbjct: 266 GPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGP 305
Score = 29.3 bits (64), Expect = 5.8
Identities = 14/40 (35%), Positives = 18/40 (45%)
Query: 50 LGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAP 89
LGAP + P +GG + P P P +P A S P
Sbjct: 128 LGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQP 167
>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
Length = 340
Score = 33.1 bits (74), Expect = 0.41
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 10/73 (13%)
Query: 51 GAPRCLRGPSAGG------QKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHS 104
GAP P GG +L ++ P GP SE P+A A+A P P+
Sbjct: 76 GAPAAPAVPGPGGVNCAVGSAMLTRAAP----GPRRSEDEPPAASASAAPPPQRDEEEPD 131
Query: 105 GSPKLGTKRLPQA 117
G P+ G P A
Sbjct: 132 GVPEKGKSSGPSA 144
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 33.1 bits (74), Expect = 0.41
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 72 PCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGSPKLGTK--RLPQALIVGVKKGGTRA 129
P PS P PS PSA +PA P+ S G P++ K R P+ V +G +
Sbjct: 589 PSRPSRP-PSHPSAHGSPAPVSTMPKRMSS--EGPPRMSPKAQRHPRNHRVSAGRGSISS 645
Query: 130 VLEFIRVHPDVRA 142
LEF+ +P A
Sbjct: 646 GLEFVSHNPPSEA 658
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 33.1 bits (74), Expect = 0.41
Identities = 35/111 (31%), Positives = 40/111 (36%), Gaps = 21/111 (18%)
Query: 4 RVLGRAGPPQPRRARRLL-FAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPSAG 62
R GR PR A RL F L S L C+ G + +G P + G
Sbjct: 246 RAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCN--GGAGDVGLPALVAEAGRG 303
Query: 63 GQK-----------------LLQKSRPC-DPSGPTPSEPSAPSAPAAAVPA 95
G K LL RPC P P P+ P P AP AA PA
Sbjct: 304 GAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPA 354
>gi|190886454 tumor specificity and mitosis phase-dependent
expression protein [Homo sapiens]
Length = 394
Score = 33.1 bits (74), Expect = 0.41
Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 19/134 (14%)
Query: 50 LGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPS---------APSAPAAAVPAPRLSG 100
LG L GPSA + Q P + + P P+EP + SA A AV L
Sbjct: 142 LGVRAPLAGPSAAARSPEQLCAPAE-AAPCPAEPERSQSAALEPSSSADAGAVACRALEA 200
Query: 101 SNHSG--SPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGL 158
+ +P+ +R + GV G + + E + +V G E RG
Sbjct: 201 DSGDARRAPRARGERRRHTIASGVDCGLLKQMKE-LEQEKEVLLQGLEM------MARGR 253
Query: 159 DWYRSLMPRTLESQ 172
DWY+ + R E Q
Sbjct: 254 DWYQQQLQRVQERQ 267
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 33.1 bits (74), Expect = 0.41
Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 1/48 (2%)
Query: 59 PSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSGSNHSGS 106
P GG Q S P P+ P P PS P P P P LSG + S
Sbjct: 137 PCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPP-PPPALSGYTTTNS 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,970,283
Number of Sequences: 37866
Number of extensions: 834925
Number of successful extensions: 6896
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 6364
Number of HSP's gapped (non-prelim): 609
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.