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Search of human proteins with 50962799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50962799 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A1 [Homo sapiens]
(133 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50962799 family with sequence similarity 19 (chemokine (C-C m... 295 9e-81
gi|32698882 family with sequence similarity 19 (chemokine (C-C m... 172 9e-44
gi|53988383 family with sequence similarity 19 (chemokine (C-C m... 172 9e-44
gi|30425496 family with sequence similarity 19 (chemokine (C-C m... 169 5e-43
gi|33300649 family with sequence similarity 19 (chemokine (C-C m... 162 7e-41
gi|53933210 family with sequence similarity 19 (chemokine (C-C m... 99 1e-21
gi|131887988 family with sequence similarity 19 (chemokine (C-C ... 97 5e-21
gi|52486734 family with sequence similarity 19 (chemokine (C-C m... 89 8e-19
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 32 0.15
gi|24041035 notch 2 preproprotein [Homo sapiens] 32 0.19
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 31 0.33
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 30 0.43
gi|110347437 latent transforming growth factor beta binding prot... 30 0.43
gi|110347412 latent transforming growth factor beta binding prot... 30 0.43
gi|110347431 latent transforming growth factor beta binding prot... 30 0.43
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 30 0.57
gi|112420992 crumbs homolog 2 [Homo sapiens] 30 0.74
gi|148833508 notch1 preproprotein [Homo sapiens] 29 0.97
gi|134244285 Notch homolog 3 [Homo sapiens] 29 0.97
gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [H... 29 0.97
gi|55770876 notch4 preproprotein [Homo sapiens] 29 0.97
gi|54873613 agrin [Homo sapiens] 29 1.3
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 29 1.3
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 28 1.6
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 28 1.6
gi|188219762 denticleless homolog [Homo sapiens] 28 2.2
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 28 2.2
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 28 2.2
gi|4557679 jagged 1 precursor [Homo sapiens] 28 2.8
gi|110735443 delta-like 1 [Homo sapiens] 27 3.7
>gi|50962799 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A1 [Homo sapiens]
Length = 133
Score = 295 bits (754), Expect = 9e-81
Identities = 133/133 (100%), Positives = 133/133 (100%)
Query: 1 MAMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEE 60
MAMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEE
Sbjct: 1 MAMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEE 60
Query: 61 RSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCAT 120
RSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCAT
Sbjct: 61 RSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCAT 120
Query: 121 GNKIKTTRIHPRT 133
GNKIKTTRIHPRT
Sbjct: 121 GNKIKTTRIHPRT 133
>gi|32698882 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A4 [Homo sapiens]
Length = 140
Score = 172 bits (435), Expect = 9e-44
Identities = 75/121 (61%), Positives = 90/121 (74%)
Query: 9 WVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCS 68
W+ ++ L S QH H+ + GTCEV+A HRCCNKNRIEERSQTVKCS
Sbjct: 18 WLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCS 77
Query: 69 CLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTR 128
C PG+VAGTTR +PSCV+ASIVI KWWC M PCLEGE+CK LPD SGW C++GNK+KTT+
Sbjct: 78 CFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTK 137
Query: 129 I 129
+
Sbjct: 138 V 138
>gi|53988383 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A4 [Homo sapiens]
Length = 140
Score = 172 bits (435), Expect = 9e-44
Identities = 75/121 (61%), Positives = 90/121 (74%)
Query: 9 WVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCS 68
W+ ++ L S QH H+ + GTCEV+A HRCCNKNRIEERSQTVKCS
Sbjct: 18 WLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCS 77
Query: 69 CLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTR 128
C PG+VAGTTR +PSCV+ASIVI KWWC M PCLEGE+CK LPD SGW C++GNK+KTT+
Sbjct: 78 CFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTK 137
Query: 129 I 129
+
Sbjct: 138 V 138
>gi|30425496 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A2 [Homo sapiens]
Length = 131
Score = 169 bits (429), Expect = 5e-43
Identities = 72/105 (68%), Positives = 83/105 (79%)
Query: 25 GSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSC 84
G + + H H + GTCEV+A HRCCNKN+IEERSQTVKCSC PG+VAGTTR PSC
Sbjct: 25 GKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSC 84
Query: 85 VDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRI 129
VDASIV KWWC M+PCLEGEECK LPD GW C++GNK+KTTR+
Sbjct: 85 VDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRV 129
>gi|33300649 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A3 isoform 1 [Homo sapiens]
Length = 133
Score = 162 bits (410), Expect = 7e-41
Identities = 68/88 (77%), Positives = 80/88 (90%)
Query: 42 GTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPC 101
GTCEVIAAHRCCN+NRIEERSQTVKCSC G+VAGTTR +PSCVDASIV+ +WWC+MEPC
Sbjct: 44 GTCEVIAAHRCCNRNRIEERSQTVKCSCFSGQVAGTTRAKPSCVDASIVLQRWWCQMEPC 103
Query: 102 LEGEECKTLPDNSGWMCATGNKIKTTRI 129
L GEECK LPD SGW C++G+K+KTT++
Sbjct: 104 LPGEECKVLPDLSGWSCSSGHKVKTTKV 131
>gi|53933210 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A5 isoform 2 [Homo sapiens]
Length = 125
Score = 99.0 bits (245), Expect = 1e-21
Identities = 52/118 (44%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
Query: 13 LWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPG 72
LW A A L C L Q + GTCE++ R ++ R QT +C+C G
Sbjct: 7 LWALAGAALCCFLVLVIHAQFLKEGQLAAGTCEIVTLDRDSSQPRRTIARQTARCACRKG 66
Query: 73 KVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCA-TGNKIKTTRI 129
++AGTTR RP+CVDA I+ K WC+M PCLEGE C L + SGW C G +IKTT +
Sbjct: 67 QIAGTTRARPACVDARIIKTKQWCDMLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTV 124
>gi|131887988 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A5 isoform 1 [Homo sapiens]
Length = 132
Score = 96.7 bits (239), Expect = 5e-21
Identities = 44/89 (49%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Query: 42 GTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPC 101
GTCE++ R ++ R QT +C+C G++AGTTR RP+CVDA I+ K WC+M PC
Sbjct: 43 GTCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVDARIIKTKQWCDMLPC 102
Query: 102 LEGEECKTLPDNSGWMCA-TGNKIKTTRI 129
LEGE C L + SGW C G +IKTT +
Sbjct: 103 LEGEGCDLLINRSGWTCTQPGGRIKTTTV 131
>gi|52486734 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A3 isoform 2 [Homo sapiens]
Length = 169
Score = 89.4 bits (220), Expect = 8e-19
Identities = 39/45 (86%), Positives = 42/45 (93%)
Query: 42 GTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVD 86
GTCEVIAAHRCCN+NRIEERSQTVKCSC G+VAGTTR +PSCVD
Sbjct: 44 GTCEVIAAHRCCNRNRIEERSQTVKCSCFSGQVAGTTRAKPSCVD 88
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 32.0 bits (71), Expect = 0.15
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 10/77 (12%)
Query: 40 EGGTCEVIAAHRCCNKNRI-EERSQTVKCSCLPGKVA-------GTTRNRPSCVDASIVI 91
EG CEV RC + ++S V C+C G+VA G N SC S ++
Sbjct: 4335 EGSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMM 4394
Query: 92 GKWWCEMEPCLEGEECK 108
+ C+ P + G C+
Sbjct: 4395 PE--CQCPPHMTGPRCE 4409
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 31.6 bits (70), Expect = 0.19
Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 11/70 (15%)
Query: 52 CCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLP 111
C N + ++ +C C PG P C I I C PCL G +C P
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFTG------PVC---QIDIDD--CSSTPCLNGAKCIDHP 551
Query: 112 DNSGWMCATG 121
+ CATG
Sbjct: 552 NGYECQCATG 561
Score = 26.9 bits (58), Expect = 4.8
Identities = 20/81 (24%), Positives = 27/81 (33%), Gaps = 25/81 (30%)
Query: 41 GGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEP 100
GGTC +++ T +C+C G T DA C P
Sbjct: 118 GGTCHMLSR-------------DTYECTCQ----VGFTGKECQWTDA--------CLSHP 152
Query: 101 CLEGEECKTLPDNSGWMCATG 121
C G C T+ + C TG
Sbjct: 153 CANGSTCTTVANQFSCKCLTG 173
Score = 26.6 bits (57), Expect = 6.3
Identities = 28/105 (26%), Positives = 36/105 (34%), Gaps = 17/105 (16%)
Query: 23 CHGSLQHTFQQHHLHRPEGGTCEV----IAAHRCCNKNRIEERSQTVKCSCLPGKVAGTT 78
C + TF+ + L EG TCE HRC N + T C C P T
Sbjct: 236 CRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPP---QWTG 292
Query: 79 RNRPSCVDASIVIGKWWCEMEP--CLEGEECKTLPDNSGWMCATG 121
+ VD C ++P C G C G +C G
Sbjct: 293 QFCTEDVDE--------CLLQPNACQNGGTCANRNGGYGCVCVNG 329
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 30.8 bits (68), Expect = 0.33
Identities = 27/105 (25%), Positives = 37/105 (35%), Gaps = 12/105 (11%)
Query: 22 LCHGSLQHTFQQHHLHRPEGGTCEV----IAAHRCCNKNRIEERSQTVKCSCLPGKVAGT 77
+C HTF L G CE+ ++ C + E+ C C PG
Sbjct: 1136 ICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHH 1195
Query: 78 TRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWM-CATG 121
N C+ S C E C+E E T G+M C+ G
Sbjct: 1196 CENELECIPNS-------CVHELCMENEPGSTCLCTPGFMTCSIG 1233
Score = 30.0 bits (66), Expect = 0.57
Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 15/85 (17%)
Query: 41 GGTCEV----IAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWC 96
G CE+ ++ C N + + C+C P + P C + + K C
Sbjct: 922 GSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEP------EYHGPFC---ELDVNK--C 970
Query: 97 EMEPCLEGEECKTLPDNSGWMCATG 121
++ PCL+ E C D +CA G
Sbjct: 971 KISPCLDEENCVYRTDGYNCLCAPG 995
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 30.4 bits (67), Expect = 0.43
Identities = 26/101 (25%), Positives = 35/101 (34%), Gaps = 26/101 (25%)
Query: 21 LLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRN 80
L C L + HH G TC + +RS T C+C PG
Sbjct: 279 LFCDQDLNYC--THHSPCKNGATC-----------SNSGQRSYT--CTCRPGYTG----- 318
Query: 81 RPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATG 121
VD + + + C+ PC G CK D +C G
Sbjct: 319 ----VDCELELSE--CDSNPCRNGGSCKDQEDGYHCLCPPG 353
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 30.4 bits (67), Expect = 0.43
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 20/79 (25%)
Query: 34 HHLHRPEGGTCEVI-----AAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDAS 88
HHLHR G C + A C + +CSC PG A + R P C D
Sbjct: 758 HHLHR---GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 811
Query: 89 IVIGKWWCEMEPCLEGEEC 107
+ CLEG+ C
Sbjct: 812 ---------VNECLEGDFC 821
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 30.4 bits (67), Expect = 0.43
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 20/79 (25%)
Query: 34 HHLHRPEGGTCEVI-----AAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDAS 88
HHLHR G C + A C + +CSC PG A + R P C D
Sbjct: 788 HHLHR---GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 841
Query: 89 IVIGKWWCEMEPCLEGEEC 107
+ CLEG+ C
Sbjct: 842 ---------VNECLEGDFC 851
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 30.4 bits (67), Expect = 0.43
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 20/79 (25%)
Query: 34 HHLHRPEGGTCEVI-----AAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDAS 88
HHLHR G C + A C + +CSC PG A + R P C D
Sbjct: 825 HHLHR---GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 878
Query: 89 IVIGKWWCEMEPCLEGEEC 107
+ CLEG+ C
Sbjct: 879 ---------VNECLEGDFC 888
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 30.0 bits (66), Expect = 0.57
Identities = 22/102 (21%), Positives = 35/102 (34%), Gaps = 14/102 (13%)
Query: 14 WISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGK 73
W+ + C L +H GGTC+ ++ H C + + CLP
Sbjct: 1024 WMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEG---WAGLACEKECLPRD 1080
Query: 74 VAGTTRNRPSCVDASIV---IGKWWCE--------MEPCLEG 104
V R+ C++ + G+ C PCL G
Sbjct: 1081 VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRG 1122
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 29.6 bits (65), Expect = 0.74
Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 11/67 (16%)
Query: 52 CCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLP 111
C + + E S CSCL G +AG P+ CE PCL G C+
Sbjct: 1144 CLDGSPCEGGSPAANCSCLEG-LAGQRCQVPTLP----------CEANPCLNGGTCRAAG 1192
Query: 112 DNSGWMC 118
S +C
Sbjct: 1193 GVSECIC 1199
Score = 29.3 bits (64), Expect = 0.97
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 20/114 (17%)
Query: 15 ISACAMLLCH--GSLQHTFQQHHLHRP---EGGTCEV----IAAHRCCNKNRIEERSQTV 65
I CA CH + ++ ++ H P G TCE+ A+ C + + +
Sbjct: 109 IDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSF 168
Query: 66 KCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCA 119
+C C PG G TR + + C+ +PC G C L + CA
Sbjct: 169 RCVCAPGY--GGTRCQLDLDE---------CQSQPCAHGGTCHDLVNGFRCDCA 211
Score = 28.5 bits (62), Expect = 1.6
Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 14/52 (26%)
Query: 67 CSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMC 118
C+C P G P+C + WC +PCL C+ +PD G++C
Sbjct: 831 CTC-PANFTG-----PTCAQ------QLWCPGQPCLPPATCEEVPD--GFVC 868
Score = 26.6 bits (57), Expect = 6.3
Identities = 10/26 (38%), Positives = 12/26 (46%)
Query: 96 CEMEPCLEGEECKTLPDNSGWMCATG 121
C PCL G C+ LP+ C G
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDG 349
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 29.3 bits (64), Expect = 0.97
Identities = 32/114 (28%), Positives = 43/114 (37%), Gaps = 25/114 (21%)
Query: 15 ISACAMLLCH--GSLQHTFQQHHLHRPEG---GTCEVIAAHRCCNKN-----RIEERSQT 64
I CA CH G+ + PEG TC ++ CN N +
Sbjct: 679 IDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC--LSEVNECNSNPCVHGACRDSLNG 736
Query: 65 VKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMC 118
KC C PG +GT + I CE PC+ G CK + SG++C
Sbjct: 737 YKCDCDPGW-SGTNCD----------INNNECESNPCVNGGTCKDM--TSGYVC 777
Score = 27.7 bits (60), Expect = 2.8
Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 20/116 (17%)
Query: 15 ISACAMLLC-HG-SLQHTFQQHHLHRP---EGGTCEV----IAAHRCCNKNRIEERSQTV 65
I+ C + C HG S Q+T + H G CE + C N + T
Sbjct: 870 INECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTA 929
Query: 66 KCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATG 121
C CLPG R + + I C +PC G C D+ C G
Sbjct: 930 FCDCLPG-------FRGTFCEEDIN----ECASDPCRNGANCTDCVDSYTCTCPAG 974
Score = 26.9 bits (58), Expect = 4.8
Identities = 17/71 (23%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 48 AAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEEC 107
A++ C N+ + KC+CL T +V+ C PC G EC
Sbjct: 796 ASNPCLNQGTCIDDVAGYKCNCLLPYTGAT---------CEVVLAP--CAPSPCRNGGEC 844
Query: 108 KTLPDNSGWMC 118
+ D + C
Sbjct: 845 RQSEDYESFSC 855
Score = 26.2 bits (56), Expect = 8.2
Identities = 16/71 (22%), Positives = 24/71 (33%), Gaps = 12/71 (16%)
Query: 48 AAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEEC 107
A+ C + +R + C C G+ +C+ PC EG C
Sbjct: 340 ASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS------------NPCNEGSNC 387
Query: 108 KTLPDNSGWMC 118
T P N +C
Sbjct: 388 DTNPVNGKAIC 398
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 29.3 bits (64), Expect = 0.97
Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 11/96 (11%)
Query: 30 TFQQHHLHRPEGGTCEVIAAHRCCNKNRI------EERSQTVKCSCLPGKVAGTTRNRPS 83
TF H G CE +A R C + + ++ + +C+C PG + R+ P
Sbjct: 1272 TFTCHCAQPFWGPRCERVA--RSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPG 1329
Query: 84 CVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCA 119
+ C PCL G C+ P + CA
Sbjct: 1330 SPPGASNAS---CAAAPCLHGGSCRPAPLAPFFRCA 1362
Score = 28.1 bits (61), Expect = 2.2
Identities = 24/85 (28%), Positives = 31/85 (36%), Gaps = 15/85 (17%)
Query: 41 GGTCEV----IAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWC 96
G CEV + C N ++R C+C P +G+T VD C
Sbjct: 463 GTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLD--VDE--------C 511
Query: 97 EMEPCLEGEECKTLPDNSGWMCATG 121
PC G +C PD CA G
Sbjct: 512 ASTPCRNGAKCVDQPDGYECRCAEG 536
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 11/70 (15%)
Query: 49 AHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECK 108
AH C+ + +C C PG + P C + + + CE +PC G C
Sbjct: 700 AHEPCSHGICYDAPGGFRCVCEPGW------SGPRCSQS---LARDACESQPCRAGGTCS 750
Query: 109 TLPDNSGWMC 118
+ D G+ C
Sbjct: 751 S--DGMGFHC 758
Score = 26.2 bits (56), Expect = 8.2
Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 44 CEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLE 103
C A H ++ +++ +C C G + P C V+ CE +PC
Sbjct: 1209 CRSGACHAAHTRDCLQDPGGGFRCLCHAGF------SGPRC---QTVLSP--CESQPCQH 1257
Query: 104 GEECKTLPDNSGWMCAT 120
G +C+ P G + T
Sbjct: 1258 GGQCRPSPGPGGGLTFT 1274
>gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [Homo
sapiens]
Length = 819
Score = 29.3 bits (64), Expect = 0.97
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 96 CEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHP 131
CE++PC EG CK S CA G+ K R P
Sbjct: 436 CELDPCCEGSTCKL---KSFAECAYGDCCKDCRFLP 468
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 29.3 bits (64), Expect = 0.97
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 15/86 (17%)
Query: 40 EGGTCEV----IAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWW 95
EG CEV A+ C N + +C CLPG +GT +D
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG-FSGTRCEED--IDE-------- 554
Query: 96 CEMEPCLEGEECKTLPDNSGWMCATG 121
C PC G +C+ P C G
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKCLPG 580
Score = 29.3 bits (64), Expect = 0.97
Identities = 20/73 (27%), Positives = 27/73 (36%), Gaps = 17/73 (23%)
Query: 52 CCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSC---VDASIVIGKWWCEMEPCLEGEECK 108
C N + +++ C CLPG P C VD C +PC G C
Sbjct: 560 CANGGQCQDQPGAFHCKCLPG------FEGPRCQTEVDE--------CLSDPCPVGASCL 605
Query: 109 TLPDNSGWMCATG 121
LP +C +G
Sbjct: 606 DLPGAFFCLCPSG 618
Score = 28.5 bits (62), Expect = 1.6
Identities = 22/85 (25%), Positives = 28/85 (32%), Gaps = 15/85 (17%)
Query: 41 GGTC--EVIAAHR--CCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWC 96
G TC E+ A H C N C+C P P C ++ +C
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG------PQCQTSTD-----YC 771
Query: 97 EMEPCLEGEECKTLPDNSGWMCATG 121
PC G C P +CA G
Sbjct: 772 VSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 28.1 bits (61), Expect = 2.2
Identities = 26/100 (26%), Positives = 32/100 (32%), Gaps = 19/100 (19%)
Query: 41 GGTCEV--IAAHRCCNKNRIEERSQTVKCSCLPGKVA------GTTRNRPSCVDASIVIG 92
G CEV A + C K +++ C C G T + C +S V
Sbjct: 621 GQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCD 680
Query: 93 KWW----CEME-------PCLEGEECKTLPDNSGWMCATG 121
W CE E PC G C P C TG
Sbjct: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Score = 27.3 bits (59), Expect = 3.7
Identities = 19/72 (26%), Positives = 22/72 (30%), Gaps = 14/72 (19%)
Query: 52 CCNKNRIEERSQTVKCSCLPGKVAGTTRN--RPSCVDASIVIGKWWCEMEPCLEGEECKT 109
C N R T C C G RPSC D+ PC C+
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADS------------PCRNRATCQD 823
Query: 110 LPDNSGWMCATG 121
P +C TG
Sbjct: 824 SPQGPRCLCPTG 835
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 28.9 bits (63), Expect = 1.3
Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 11/46 (23%)
Query: 67 CSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPD 112
C C PG+V P+C D K C+ PC C+ LP+
Sbjct: 1574 CQCPPGRVG------PTCADE-----KSPCQPNPCHGAAPCRVLPE 1608
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 28.9 bits (63), Expect = 1.3
Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 76 GTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCAT 120
G + R C S + C PC G +C + PD S W C +
Sbjct: 535 GDVQERQMCNKRSCPVDG--CLSNPCFPGAQCSSFPDGS-WSCGS 576
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 28.5 bits (62), Expect = 1.6
Identities = 22/90 (24%), Positives = 34/90 (37%), Gaps = 17/90 (18%)
Query: 49 AHRCCNKNRIEERSQTVKCSCLPG------KVAGTTRNRPS-CVDASIVIGKWWCEMEPC 101
A+ C N + T +C+C PG VA + P+ CV+ +G C
Sbjct: 680 AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC 739
Query: 102 LEG----------EECKTLPDNSGWMCATG 121
+G +C LP +G +C G
Sbjct: 740 RDGWEGRTCTHNTNDCNPLPCYNGGICVDG 769
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 28.5 bits (62), Expect = 1.6
Identities = 22/90 (24%), Positives = 34/90 (37%), Gaps = 17/90 (18%)
Query: 49 AHRCCNKNRIEERSQTVKCSCLPG------KVAGTTRNRPS-CVDASIVIGKWWCEMEPC 101
A+ C N + T +C+C PG VA + P+ CV+ +G C
Sbjct: 718 AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC 777
Query: 102 LEG----------EECKTLPDNSGWMCATG 121
+G +C LP +G +C G
Sbjct: 778 RDGWEGRTCTHNTNDCNPLPCYNGGICVDG 807
>gi|188219762 denticleless homolog [Homo sapiens]
Length = 730
Score = 28.1 bits (61), Expect = 2.2
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 42 GTCEVIAAHRCCNKNRIEERSQT----VKCSCLPGKVAGTTRNRPSCVD---ASIVIGKW 94
G E + CC E+ S+ K S + G AGT+ + P AS G
Sbjct: 579 GQVENLHLDLCCLAGNQEDLSKDSLGPTKSSKIEG--AGTSISEPPSPISPYASESCGTL 636
Query: 95 WCEMEPCLEGEEC----KTLPDNSGWMCATGNKIKTTRIHPRT 133
+ PC EG E + P+N W+ A K K PR+
Sbjct: 637 PLPLRPCGEGSEMVGKENSSPENKNWLLAMAAKRKAENPSPRS 679
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 28.1 bits (61), Expect = 2.2
Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 7/40 (17%)
Query: 96 CEMEPCLEGEECKTLPDNSGWMCA------TGNKIKTTRI 129
C PC G +C + PD S W C +GN I+ T +
Sbjct: 551 CLSNPCFAGVKCTSYPDGS-WKCGACPPGYSGNGIQCTDV 589
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 28.1 bits (61), Expect = 2.2
Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 41 GGTCEVIAAHRCCN-----KNRIEER--SQTVKCSCLPGKVAGTTRNRPSCVDASIVIGK 93
GGTC + C+ R ER ++ ++ C G + +CV + GK
Sbjct: 3874 GGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGK 3933
Query: 94 W------WCEMEPCLEGEECKTLPDNSGWMCATG 121
+CE PC G C++ D+ C G
Sbjct: 3934 MCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFG 3967
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 27.7 bits (60), Expect = 2.8
Identities = 28/113 (24%), Positives = 38/113 (33%), Gaps = 34/113 (30%)
Query: 41 GGTCEVIA----AHRCCNKNRIEERSQTVKCSCLPGKVA-----------GTTRNRPSCV 85
G TC++ A A C N + + C CLPG + G +N SC
Sbjct: 406 GKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCR 465
Query: 86 DASIVIGKWW-----------------CEMEPCLEGEECKTLPDNSGWMCATG 121
D +V G C PCL G C+ + +C TG
Sbjct: 466 D--LVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Score = 26.6 bits (57), Expect = 6.3
Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 13/69 (18%)
Query: 50 HRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKT 109
H C N + +C C PG AG D I I + C+ PC G C
Sbjct: 789 HPCYNSGTCVDGDNWYRCECAPG-FAGP--------DCRININE--CQSSPCAFGATC-- 835
Query: 110 LPDNSGWMC 118
+ + +G+ C
Sbjct: 836 VDEINGYRC 844
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 27.3 bits (59), Expect = 3.7
Identities = 25/101 (24%), Positives = 32/101 (31%), Gaps = 26/101 (25%)
Query: 21 LLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRN 80
L C+ L + HH G TC + S T CSC PG T
Sbjct: 283 LFCNQDLNYC--THHKPCKNGATC-----------TNTGQGSYT--CSCRPGYTGATCE- 326
Query: 81 RPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATG 121
+G C+ PC G C L ++ C G
Sbjct: 327 ----------LGIDECDPSPCKNGGSCTDLENSYSCTCPPG 357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.133 0.467
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,988,827
Number of Sequences: 37866
Number of extensions: 261246
Number of successful extensions: 813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 724
Number of HSP's gapped (non-prelim): 119
length of query: 133
length of database: 18,247,518
effective HSP length: 91
effective length of query: 42
effective length of database: 14,801,712
effective search space: 621671904
effective search space used: 621671904
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.