Guide to the Human Genome
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Search of human proteins with 50843827

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50843827 activating molecule in beclin-1-regulated autophagy
[Homo sapiens]
         (1208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50843827 activating molecule in beclin-1-regulated autophagy ...  2432   0.0  
gi|23199987 WD repeat domain 5B [Homo sapiens]                         65   4e-10
gi|16554629 WD repeat domain 5 [Homo sapiens]                          63   2e-09
gi|16554627 WD repeat domain 5 [Homo sapiens]                          63   2e-09
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]              57   8e-08
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]              57   8e-08
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]              57   8e-08
gi|113865883 WD repeat domain 38 [Homo sapiens]                        54   9e-07
gi|32189425 WD repeat domain 69 [Homo sapiens]                         54   1e-06
gi|83779014 katanin p80 subunit B 1 [Homo sapiens]                     52   3e-06
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ...    52   4e-06
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]     52   4e-06
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]       51   6e-06
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]             49   3e-05
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]             49   3e-05
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]             49   3e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     49   4e-05
gi|13376840 WD repeat domain 61 [Homo sapiens]                         49   4e-05
gi|148536855 coatomer protein complex, subunit alpha isoform 1 [...    48   5e-05
gi|148536853 coatomer protein complex, subunit alpha isoform 2 [...    48   5e-05
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s...    48   6e-05
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]    48   6e-05
gi|4557467 excision repair cross-complementing rodent repair def...    47   1e-04
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]          47   1e-04
gi|19913369 transducin beta-like 3 [Homo sapiens]                      47   1e-04
gi|5174447 guanine nucleotide binding protein (G protein), beta ...    46   2e-04
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]              46   2e-04
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]               46   2e-04
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]          45   3e-04
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]          45   3e-04

>gi|50843827 activating molecule in beclin-1-regulated autophagy [Homo
            sapiens]
          Length = 1208

 Score = 2432 bits (6303), Expect = 0.0
 Identities = 1208/1208 (100%), Positives = 1208/1208 (100%)

Query: 1    MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA 60
            MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA
Sbjct: 1    MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA 60

Query: 61   FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
            FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV
Sbjct: 61   FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120

Query: 121  RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM 180
            RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM
Sbjct: 121  RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM 180

Query: 181  ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL 240
            ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL
Sbjct: 181  ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL 240

Query: 241  HNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGP 300
            HNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGP
Sbjct: 241  HNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGP 300

Query: 301  TRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSV 360
            TRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSV
Sbjct: 301  TRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSV 360

Query: 361  LRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEY 420
            LRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEY
Sbjct: 361  LRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEY 420

Query: 421  DRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRA 480
            DRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRA
Sbjct: 421  DRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRA 480

Query: 481  CHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSS 540
            CHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSS
Sbjct: 481  CHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSS 540

Query: 541  RLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLR 600
            RLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLR
Sbjct: 541  RLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLR 600

Query: 601  RRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQ 660
            RRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQ
Sbjct: 601  RRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQ 660

Query: 661  NRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFL 720
            NRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFL
Sbjct: 661  NRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFL 720

Query: 721  LPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKF 780
            LPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKF
Sbjct: 721  LPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKF 780

Query: 781  DLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHN 840
            DLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHN
Sbjct: 781  DLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHN 840

Query: 841  LGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETS 900
            LGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETS
Sbjct: 841  LGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETS 900

Query: 901  MRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWD 960
            MRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWD
Sbjct: 901  MRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWD 960

Query: 961  QLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQ 1020
            QLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQ
Sbjct: 961  QLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQ 1020

Query: 1021 LQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQST 1080
            LQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQST
Sbjct: 1021 LQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQST 1080

Query: 1081 TMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRT 1140
            TMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRT
Sbjct: 1081 TMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRT 1140

Query: 1141 ASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAG 1200
            ASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAG
Sbjct: 1141 ASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAG 1200

Query: 1201 PRGEPRNR 1208
            PRGEPRNR
Sbjct: 1201 PRGEPRNR 1208


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 47/140 (33%), Positives = 67/140 (47%), Gaps = 7/140 (5%)

Query: 34  EDKTR--WMKWEGKRVE-LPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHS 90
           +DKT   W    GK ++ L       F   F+P   L+ S   +  + I EVKTGKC+ +
Sbjct: 103 DDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKT 162

Query: 91  LIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS--ESWFTDSNNAIASLAFHPT 148
           L  H      V F+ +   LI SG  DG  RIWD   G   ++   D N  ++ + F P 
Sbjct: 163 LSAHSDPVSAVHFNCS-GSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPN 221

Query: 149 AQLLLIATA-NEIHFWDWSR 167
            + +L AT  N +  WD+SR
Sbjct: 222 GKYILTATLDNTLKLWDYSR 241



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 40/147 (27%), Positives = 79/147 (53%), Gaps = 8/147 (5%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           +A+S D + L S   +  + + +V++GKC+ +L GH    +C  F+P  S LI SG  D 
Sbjct: 89  VAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPP-SNLIISGSFDE 147

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANEI-HFWDWSRREPFAVVKT 176
            V+IW++  G      +  ++ ++++ F+ +  L++  + + +   WD +  +    +KT
Sbjct: 148 TVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQ---CLKT 204

Query: 177 ASEMER--VRLVRFDPLGHYLLTAIVN 201
             + +   V  V+F P G Y+LTA ++
Sbjct: 205 LVDDDNPPVSFVKFSPNGKYILTATLD 231



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 51  DSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISG- 109
           D+P  +F+  FSP+   + +  +++ + + +   G+C+ +  GH+   +C+  + +++G 
Sbjct: 209 DNPPVSFV-KFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGG 267

Query: 110 -LIASGCLDGEVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIA 155
             I SG  D  V IW+L             + + S A HPT  L+  A
Sbjct: 268 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASA 315


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 8/147 (5%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           +A+S D  LL S   +  + I +V +GKC+ +L GH    +C  F+P  S LI SG  D 
Sbjct: 93  VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDE 151

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANEI-HFWDWSRREPFAVVKT 176
            VRIWD+  G         ++ ++++ F+    L++ ++ + +   WD +  +    +KT
Sbjct: 152 SVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ---CLKT 208

Query: 177 ASEMER--VRLVRFDPLGHYLLTAIVN 201
             + +   V  V+F P G Y+L A ++
Sbjct: 209 LIDDDNPPVSFVKFSPNGKYILAATLD 235



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 7/146 (4%)

Query: 28  LLQELVEDKTR--WMKWEGKRVE-LPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKT 84
           LL    +DKT   W    GK ++ L       F   F+P   L+ S   + ++ I +VKT
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160

Query: 85  GKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS--ESWFTDSNNAIAS 142
           GKC+ +L  H      V F+     LI S   DG  RIWD   G   ++   D N  ++ 
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 219

Query: 143 LAFHPTAQLLLIATA-NEIHFWDWSR 167
           + F P  + +L AT  N +  WD+S+
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSK 245



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 51  DSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISG- 109
           D+P  +F+  FSP+   + +  +++ + + +   GKC+ +  GH+   +C+  + +++G 
Sbjct: 213 DNPPVSFV-KFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 271

Query: 110 -LIASGCLDGEVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIA 155
             I SG  D  V IW+L             + + S A HPT  ++  A
Sbjct: 272 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 8/147 (5%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           +A+S D  LL S   +  + I +V +GKC+ +L GH    +C  F+P  S LI SG  D 
Sbjct: 93  VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDE 151

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANEI-HFWDWSRREPFAVVKT 176
            VRIWD+  G         ++ ++++ F+    L++ ++ + +   WD +  +    +KT
Sbjct: 152 SVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ---CLKT 208

Query: 177 ASEMER--VRLVRFDPLGHYLLTAIVN 201
             + +   V  V+F P G Y+L A ++
Sbjct: 209 LIDDDNPPVSFVKFSPNGKYILAATLD 235



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 7/146 (4%)

Query: 28  LLQELVEDKTR--WMKWEGKRVE-LPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKT 84
           LL    +DKT   W    GK ++ L       F   F+P   L+ S   + ++ I +VKT
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160

Query: 85  GKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS--ESWFTDSNNAIAS 142
           GKC+ +L  H      V F+     LI S   DG  RIWD   G   ++   D N  ++ 
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 219

Query: 143 LAFHPTAQLLLIATA-NEIHFWDWSR 167
           + F P  + +L AT  N +  WD+S+
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSK 245



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 51  DSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISG- 109
           D+P  +F+  FSP+   + +  +++ + + +   GKC+ +  GH+   +C+  + +++G 
Sbjct: 213 DNPPVSFV-KFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 271

Query: 110 -LIASGCLDGEVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIA 155
             I SG  D  V IW+L             + + S A HPT  ++  A
Sbjct: 272 KWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319


>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
          Length = 919

 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 14/150 (9%)

Query: 76  NIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS-----E 130
           NIY T+ + G+ +H+L GH  T   +  +     +IASG  D  VR WDL   S      
Sbjct: 736 NIYTTDCQRGQGLHALSGH--TGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVG 793

Query: 131 SWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTASEMERVRLVRFD 189
           + F  + +A+AS+A  P+ +LL  AT  E      +  R    V         VR VRF 
Sbjct: 794 TTFHGTGSAVASVAVDPSGRLL--ATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFS 851

Query: 190 PLGHYLLTAI----VNPSNQQGDDEPEIPI 215
           P  HYLLT      +  ++ QGD   ++PI
Sbjct: 852 PGAHYLLTGSYDMKIKVTDLQGDLTKQLPI 881


>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
          Length = 927

 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 14/150 (9%)

Query: 76  NIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS-----E 130
           NIY T+ + G+ +H+L GH  T   +  +     +IASG  D  VR WDL   S      
Sbjct: 744 NIYTTDCQRGQGLHALSGH--TGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVG 801

Query: 131 SWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTASEMERVRLVRFD 189
           + F  + +A+AS+A  P+ +LL  AT  E      +  R    V         VR VRF 
Sbjct: 802 TTFHGTGSAVASVAVDPSGRLL--ATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFS 859

Query: 190 PLGHYLLTAI----VNPSNQQGDDEPEIPI 215
           P  HYLLT      +  ++ QGD   ++PI
Sbjct: 860 PGAHYLLTGSYDMKIKVTDLQGDLTKQLPI 889


>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
          Length = 920

 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 14/150 (9%)

Query: 76  NIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS-----E 130
           NIY T+ + G+ +H+L GH  T   +  +     +IASG  D  VR WDL   S      
Sbjct: 737 NIYTTDCQRGQGLHALSGH--TGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVG 794

Query: 131 SWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTASEMERVRLVRFD 189
           + F  + +A+AS+A  P+ +LL  AT  E      +  R    V         VR VRF 
Sbjct: 795 TTFHGTGSAVASVAVDPSGRLL--ATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFS 852

Query: 190 PLGHYLLTAI----VNPSNQQGDDEPEIPI 215
           P  HYLLT      +  ++ QGD   ++PI
Sbjct: 853 PGAHYLLTGSYDMKIKVTDLQGDLTKQLPI 882


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FSPD  L AS   +  + + +V   KC+  L GH+R+   V+F P  S  +ASG  D  V
Sbjct: 71  FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPD-SRQLASGGWDKRV 129

Query: 121 RIWDLHGGSE-SWFTDSNNAIASLAFHPTAQLLLIAT-ANEIHFWD 164
            +WD+  G          ++I S  F PT   L   +  + +H WD
Sbjct: 130 MLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWD 175



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 5/114 (4%)

Query: 54  RSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIAS 113
           RS   ++FSPD   LAS   +  + + +V++G+ +  L+GHR +     F PT++  +A+
Sbjct: 106 RSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVN-CLAT 164

Query: 114 GCLDGEVRIWDLH----GGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFW 163
           G  D  V IWDL       S       +  I+ L +  +  L   +    IH W
Sbjct: 165 GSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGLLASGSWDKTIHIW 218



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLD 117
           +AFSPD   LAS   +  + + +  TGKC+ +L G         F P    ++ SG  D
Sbjct: 239 IAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPD-GKILVSGAAD 296


>gi|32189425 WD repeat domain 69 [Homo sapiens]
          Length = 415

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 5/130 (3%)

Query: 39  WMKWEGKRVELPDSPRST-FLLAFS-PDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRR 96
           W    G+ +   +  R+  + +AF+ P    +A+   +    +  V+TGKC H+  GH  
Sbjct: 119 WDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTA 178

Query: 97  TPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNA-IASLAFHPTAQLLLIA 155
              C++F+P  S L+A+G +D   ++WD+  G E +    ++A I SL+F+ +   ++  
Sbjct: 179 EIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITG 237

Query: 156 TANE-IHFWD 164
           + +  +  WD
Sbjct: 238 SFDHTVVVWD 247



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 5/141 (3%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L+F+     + +   +H + + +  TG+ V+ LIGH       +F+   S LI +G +D 
Sbjct: 225 LSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCS-LILTGSMDK 283

Query: 119 EVRIWD-LHGGSESWFTDSNNAIASLAFHPTAQLLLIATAN-EIHFWDWSRREPFAVVKT 176
             ++WD  +G   +  T  ++ I    F  T +L+  A+A+     +  + R+   + K 
Sbjct: 284 TCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRK--CIAKL 341

Query: 177 ASEMERVRLVRFDPLGHYLLT 197
                 +  + F+P G++LLT
Sbjct: 342 EGHEGEISKISFNPQGNHLLT 362


>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 44/137 (32%), Positives = 61/137 (44%), Gaps = 7/137 (5%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L F P    +AS   + NI + +++   CV    GH +   C+ F P     +AS   D 
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD-GKWLASAADDH 169

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVK- 175
            V++WDL  G   S F      +  + FHP   LL   +++  I FWD    E F VV  
Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD---LEKFQVVSC 226

Query: 176 TASEMERVRLVRFDPLG 192
              E   VR V F+P G
Sbjct: 227 IEGEPGPVRSVLFNPDG 243



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 2/117 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L FSPD   LAS   +H + + ++  GK +    GH      V FHP    L+ASG  D 
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN-EYLLASGSSDR 211

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVV 174
            +R WDL      S        + S+ F+P    L     + +  + W     F VV
Sbjct: 212 TIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVV 268



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 32/139 (23%), Positives = 65/139 (46%), Gaps = 7/139 (5%)

Query: 62  SPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVR 121
           +P+  ++A +  + +I + +++  K + +L+GH+     + FHP     +ASG  D  ++
Sbjct: 73  TPEELIVAGSQ-SGSIRVWDLEAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIK 130

Query: 122 IWDL-HGGSESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTASE 179
           +WD+   G    +   + A+  L F P  + L  A  +  +  WD +  +  +  +    
Sbjct: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMS--EFPGH 188

Query: 180 MERVRLVRFDPLGHYLLTA 198
              V +V F P   YLL +
Sbjct: 189 TGPVNVVEFHP-NEYLLAS 206


>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
           sapiens]
          Length = 421

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 3/140 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F  D+ LLA+   N  I I +V TGK + +L+ H      +TF P  S ++ S   D  +
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195

Query: 121 RIWDL--HGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTAS 178
           R+WDL   G          N + S AF P + +L    A++  F  W+  +   + K   
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFL-WNMDKYTMIRKLEG 254

Query: 179 EMERVRLVRFDPLGHYLLTA 198
               V    F P G  L TA
Sbjct: 255 HHHDVVACDFSPDGALLATA 274



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 1/69 (1%)

Query: 60  AFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGE 119
           AFSPD ++L S   +  +++  +     +  L GH        F P    L+A+   D  
Sbjct: 221 AFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPD-GALLATASYDTR 279

Query: 120 VRIWDLHGG 128
           V IWD H G
Sbjct: 280 VYIWDPHNG 288


>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
          Length = 589

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 35  DKT--RWMKWEGKRVELPDSPRSTFL-LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSL 91
           DKT   W   +G  V L    R   L LAFSP+   LAS   +  + + ++ +G     L
Sbjct: 447 DKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKEL 506

Query: 92  IGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDL 125
            GH      +TF P  SGLIAS  +D  VR+WD+
Sbjct: 507 RGHTDNITSLTFSPD-SGLIASASMDNSVRVWDI 539



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F P+   LA+   +  + +   + G  V    GHR     + F P     +AS   D  +
Sbjct: 434 FHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPN-GKYLASAGEDQRL 492

Query: 121 RIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATA-NEIHFWD 164
           ++WDL  G+         + I SL F P + L+  A+  N +  WD
Sbjct: 493 KLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWD 538


>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
          Length = 631

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 5/137 (3%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F P    LA++  +  + + ++  G C+ +  GH R  W  T+H +    +AS  LD   
Sbjct: 402 FHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWH-SCGNFVASSSLDKTS 460

Query: 121 RIWDLHG-GSESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTAS 178
           +IWD++            +++ S+ F P +  LL ++A++ +  WD   R          
Sbjct: 461 KIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWD--ARTGICEQSLYG 518

Query: 179 EMERVRLVRFDPLGHYL 195
            M  +    FDP GH +
Sbjct: 519 HMHSINDAIFDPRGHMI 535



 Score = 31.2 bits (69), Expect = 6.2
 Identities = 29/116 (25%), Positives = 46/116 (39%), Gaps = 15/116 (12%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           + F P    L ++  +  + I + +TG C  SL GH  +     F P    +IAS    G
Sbjct: 484 IEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPR-GHMIASCDACG 542

Query: 119 EVRIWDLH-------------GGSESWFTDSNNAIASLAFHPTAQLLLIATANEIH 161
             ++WD                G+E  F  S   +A  + +    LL +  + EIH
Sbjct: 543 VTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDL-KSGEIH 597


>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
          Length = 369

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 4/100 (4%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FSPD  L+ S   +  + + +  + +CVHS   H      V FHP+ + + A+G +D  V
Sbjct: 115 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAG-MDNTV 173

Query: 121 RIWDL--HGGSESWFTDSNNAIASLAFHPTAQLLLIATAN 158
           ++WD+  H   + +   S  A+  L+FHP+   L+ A+++
Sbjct: 174 KVWDVRTHRLLQHYQLHS-AAVNGLSFHPSGNYLITASSD 212



 Score = 37.4 bits (85), Expect = 0.087
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)

Query: 77  IYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDS 136
           + +  +K     +   GH+    CV F P+   L+ASG  D  VRIW  +   ES    +
Sbjct: 5   LMVWHMKPQSRAYRFTGHKDAVTCVNFSPS-GHLLASGSRDKTVRIWVPNVKGESTVFRA 63

Query: 137 NNA-IASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHY 194
           + A + S+ F    Q  + A+ ++ +  W   R++   +   +  +  VR  +F P G  
Sbjct: 64  HTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK--FLFSLSQHINWVRCAKFSPDGRL 121

Query: 195 LLTA 198
           +++A
Sbjct: 122 IVSA 125



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L+F P    L +   +  + I ++  G+ +++L GH+     V F  T     ASG  D 
Sbjct: 197 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT-GEYFASGGSDE 255

Query: 119 EVRIW 123
           +V +W
Sbjct: 256 QVMVW 260


>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
          Length = 359

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 4/100 (4%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FSPD  L+ S   +  + + +  + +CVHS   H      V FHP+ + + A+G +D  V
Sbjct: 153 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAG-MDNTV 211

Query: 121 RIWDL--HGGSESWFTDSNNAIASLAFHPTAQLLLIATAN 158
           ++WD+  H   + +   S  A+  L+FHP+   L+ A+++
Sbjct: 212 KVWDVRTHRLLQHYQLHS-AAVNGLSFHPSGNYLITASSD 250



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 5/140 (3%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FS +   LAS  ++  + +  +K     +   GH+    CV F P+   L+ASG  D  V
Sbjct: 27  FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS-GHLLASGSRDKTV 85

Query: 121 RIWDLHGGSESWFTDSNNA-IASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTAS 178
           RIW  +   ES    ++ A + S+ F    Q  + A+ ++ +  W   R++   +   + 
Sbjct: 86  RIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK--FLFSLSQ 143

Query: 179 EMERVRLVRFDPLGHYLLTA 198
            +  VR  +F P G  +++A
Sbjct: 144 HINWVRCAKFSPDGRLIVSA 163



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L+F P    L +   +  + I ++  G+ +++L GH+     V F  T     ASG  D 
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT-GEYFASGGSDE 293

Query: 119 EVRIW 123
           +V +W
Sbjct: 294 QVMVW 298


>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
          Length = 407

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 4/100 (4%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FSPD  L+ S   +  + + +  + +CVHS   H      V FHP+ + + A+G +D  V
Sbjct: 153 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAG-MDNTV 211

Query: 121 RIWDL--HGGSESWFTDSNNAIASLAFHPTAQLLLIATAN 158
           ++WD+  H   + +   S  A+  L+FHP+   L+ A+++
Sbjct: 212 KVWDVRTHRLLQHYQLHS-AAVNGLSFHPSGNYLITASSD 250



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 5/140 (3%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           FS +   LAS  ++  + +  +K     +   GH+    CV F P+   L+ASG  D  V
Sbjct: 27  FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS-GHLLASGSRDKTV 85

Query: 121 RIWDLHGGSESWFTDSNNA-IASLAFHPTAQLLLIATANE-IHFWDWSRREPFAVVKTAS 178
           RIW  +   ES    ++ A + S+ F    Q  + A+ ++ +  W   R++   +   + 
Sbjct: 86  RIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK--FLFSLSQ 143

Query: 179 EMERVRLVRFDPLGHYLLTA 198
            +  VR  +F P G  +++A
Sbjct: 144 HINWVRCAKFSPDGRLIVSA 163



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L+F P    L +   +  + I ++  G+ +++L GH+     V F  T     ASG  D 
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT-GEYFASGGSDE 293

Query: 119 EVRIW 123
           +V +W
Sbjct: 294 QVMVW 298


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F P+   +A+   +  + + +V  G CV    GH+     +TF P     +A+G  DG V
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN-GRFLATGATDGRV 693

Query: 121 RIWDL-HGGSESWFTDSNNAIASLAFHPTAQLLLIATA-NEIHFWD 164
            +WD+ HG          + + SL F    ++L   +  N +  WD
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 38/149 (25%), Positives = 52/149 (34%), Gaps = 45/149 (30%)

Query: 60  AFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPW-------------------- 99
           +FSPDR  L S+  +  + +  ++T  C+    GH    W                    
Sbjct: 550 SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVA 609

Query: 100 ----------------------CVTFHPTISGLIASGCLDGEVRIWD-LHGGSESWFTDS 136
                                 C  FHP  S  +A+G  D  VR+WD L+G     FT  
Sbjct: 610 RLWATDHYQPLRIFAGHLADVNCTRFHPN-SNYVATGSADRTVRLWDVLNGNCVRIFTGH 668

Query: 137 NNAIASLAFHPTAQLLLI-ATANEIHFWD 164
              I SL F P  + L   AT   +  WD
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWD 697



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           L FSP+   LA+   +  + + ++  G  V  L GH  T   + F      ++ASG +D 
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRD-GEILASGSMDN 733

Query: 119 EVRIWDLHGGSESWFTDS-NNAIASLAFHPTAQLLLIAT 156
            VR+WD     E   TD    A   +     +Q LL+ T
Sbjct: 734 TVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772


>gi|13376840 WD repeat domain 61 [Homo sapiens]
          Length = 305

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 5/130 (3%)

Query: 43  EGKRVELPDSPRSTFLL--AFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWC 100
           E  + E     R  F+L  A+SPD   LAS  ++  I I ++ TGK +H+L GH      
Sbjct: 136 ESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRS 195

Query: 101 VTFHPTISGLIASGCLDGEVRIWDL-HGGSESWFTDSNNAIASLAFHPTAQLLLIATANE 159
           +TF P  S L+ +   DG ++I+D+ H       +   + + ++AF P     + +++++
Sbjct: 196 LTFSPD-SQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDK 254

Query: 160 -IHFWDWSRR 168
            +  WD   R
Sbjct: 255 SVKVWDVGTR 264



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 5/121 (4%)

Query: 39  WMKWEGKRVELPDS-PRSTFLLAFSPDRTLLAS-THVNHNIYITEVKTGKCVHSLIGHRR 96
           W    GK+++  D+ P   + LAFSPD   LA+ THV   + I  V++GK  +SL    +
Sbjct: 91  WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVG-KVNIFGVESGKKEYSLDTRGK 149

Query: 97  TPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSN-NAIASLAFHPTAQLLLIA 155
               + + P     +ASG +DG + I+D+  G      + +   I SL F P +QLL+ A
Sbjct: 150 FILSIAYSPD-GKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208

Query: 156 T 156
           +
Sbjct: 209 S 209



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 33/146 (22%), Positives = 69/146 (47%), Gaps = 9/146 (6%)

Query: 12  ILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRT----L 67
           + WG  +   +   + ++   ++D  +  KW  +R++L  S     L   S D +    +
Sbjct: 22  VAWGTNKKENS---ETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPI 78

Query: 68  LASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHG 127
            AS+ ++ +I + +++ GK + S+       W + F P  S  +A+G   G+V I+ +  
Sbjct: 79  AASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD-SQYLATGTHVGKVNIFGVES 137

Query: 128 GSESWFTDSNNA-IASLAFHPTAQLL 152
           G + +  D+    I S+A+ P  + L
Sbjct: 138 GKKEYSLDTRGKFILSIAYSPDGKYL 163



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 1/66 (1%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           +AF PD T   S+  + ++ + +V T  CVH+   H+   W V ++   S +++ G  D 
Sbjct: 238 VAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGD-DQ 296

Query: 119 EVRIWD 124
           E+ I+D
Sbjct: 297 EIHIYD 302


>gi|148536855 coatomer protein complex, subunit alpha isoform 1
           [Homo sapiens]
          Length = 1233

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 7/85 (8%)

Query: 89  HSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDS----NNAIASLA 144
           H L GH R      FHPT+  LI SG  D +V+IW ++  S++W  D+     N ++   
Sbjct: 199 HVLEGHDRGVNWAAFHPTMP-LIVSGADDRQVKIWRMN-ESKAWEVDTCRGHYNNVSCAV 256

Query: 145 FHPTAQLLLIATANE-IHFWDWSRR 168
           FHP  +L+L  + ++ I  WD S+R
Sbjct: 257 FHPRQELILSNSEDKSIRVWDMSKR 281



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 51  DSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGL 110
           D  R+TF   F  +   + S   +  I +   ++  CV  L GH     C  FHPT   L
Sbjct: 94  DYIRTTF---FHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPT-EDL 149

Query: 111 IASGCLDGEVRIWDLHG 127
           + S  LD  VR+WD+ G
Sbjct: 150 VVSASLDQTVRVWDISG 166



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 3/108 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F   + L  S   ++ I +   K  +C+ +L+GH        FH     ++ S   D  +
Sbjct: 59  FHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL-SASDDQTI 117

Query: 121 RIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWS 166
           R+W+    +     T  N+ +    FHPT  L++ A+ ++ +  WD S
Sbjct: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS 165


>gi|148536853 coatomer protein complex, subunit alpha isoform 2
           [Homo sapiens]
          Length = 1224

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 7/85 (8%)

Query: 89  HSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDS----NNAIASLA 144
           H L GH R      FHPT+  LI SG  D +V+IW ++  S++W  D+     N ++   
Sbjct: 199 HVLEGHDRGVNWAAFHPTMP-LIVSGADDRQVKIWRMN-ESKAWEVDTCRGHYNNVSCAV 256

Query: 145 FHPTAQLLLIATANE-IHFWDWSRR 168
           FHP  +L+L  + ++ I  WD S+R
Sbjct: 257 FHPRQELILSNSEDKSIRVWDMSKR 281



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 51  DSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGL 110
           D  R+TF   F  +   + S   +  I +   ++  CV  L GH     C  FHPT   L
Sbjct: 94  DYIRTTF---FHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPT-EDL 149

Query: 111 IASGCLDGEVRIWDLHG 127
           + S  LD  VR+WD+ G
Sbjct: 150 VVSASLDQTVRVWDISG 166



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 3/108 (2%)

Query: 61  FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV 120
           F   + L  S   ++ I +   K  +C+ +L+GH        FH     ++ S   D  +
Sbjct: 59  FHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL-SASDDQTI 117

Query: 121 RIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWDWS 166
           R+W+    +     T  N+ +    FHPT  L++ A+ ++ +  WD S
Sbjct: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS 165


>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
           sapiens]
          Length = 514

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISG--------L 110
           + + P   LLAS   +  + I  +K   CVH L  H +  + + + PT  G        +
Sbjct: 355 IKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLM 414

Query: 111 IASGCLDGEVRIWDLHGG-SESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWD 164
           +AS   D  VR+WD+  G      T     + S+AF P  + L   + ++ +H W+
Sbjct: 415 LASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470


>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
          Length = 919

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 52  SPRSTFLLAFSPDRT---LLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTIS 108
           SPR T     + D +   + A    +  I++  ++TG+ +  L GH      + F+P + 
Sbjct: 455 SPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP-MK 513

Query: 109 GLIASGCLDGEVRIWDLHGGSESWFTDSNNAIAS----LAFHPTAQLLLIATAN-EIHFW 163
            ++AS   D  VR+WD+    +SW T    A+ S    + F P    L +AT N +I FW
Sbjct: 514 SVLASASWDKTVRLWDMF---DSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFW 570

Query: 164 D 164
           D
Sbjct: 571 D 571



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 1/72 (1%)

Query: 55  STFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASG 114
           S   LA+SPD   + +   +  + +    +G C  +   H      VTF  T   ++ + 
Sbjct: 375 SMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTAT-GYVVVTS 433

Query: 115 CLDGEVRIWDLH 126
            +DG VR +DLH
Sbjct: 434 SMDGTVRAFDLH 445


>gi|4557467 excision repair cross-complementing rodent repair
           deficiency, complementation group 8 isoform 1 [Homo
           sapiens]
          Length = 396

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 18/111 (16%)

Query: 77  IYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDL----------- 125
           + + ++K+G C H L GHR+    V++ P    ++A+   D  V++WD+           
Sbjct: 168 VQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLITLD 227

Query: 126 -HGGSESWFTDS-----NNAIASLAFHPTA-QLLLIATANEIHFWDWSRRE 169
            H G +S   +S     N  +  L F      LL + T N +  W+ S  E
Sbjct: 228 QHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGE 278


>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
          Length = 773

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 1/113 (0%)

Query: 46  RVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHP 105
           + EL  S  + + LA SPD  +  S   + NI + ++     V    GH     C+    
Sbjct: 570 KAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISN 629

Query: 106 TISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATAN 158
             + L   G LD  VR WDL  G +    D  + I SL + PT + L +   N
Sbjct: 630 DGTKLWTGG-LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMEN 681


>gi|19913369 transducin beta-like 3 [Homo sapiens]
          Length = 808

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 101 VTFHPTISGLIASGCLDGEVRIWDL--HGGSESWFTDSNNAIASLAFHP-TAQLLLIATA 157
           + F PT S L+A+G  DG VR+WD+  H G+   F  S   +  +AFHP   +LLL ++A
Sbjct: 115 MAFDPT-STLLATGGCDGAVRVWDIVRHYGTHH-FRGSPGVVHLVAFHPDPTRLLLFSSA 172

Query: 158 NEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTA 198
            +     WS ++   +    +    V  + F   GH +L++
Sbjct: 173 TDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSS 213



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 11/151 (7%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIA-SGCLD 117
           +AF P  TLLA+   +  + + ++      H   G       V FHP  + L+  S   D
Sbjct: 115 MAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATD 174

Query: 118 GEVRIWDLHGGS-ESWFTDSNNAIASLAFHPTAQLLLIATANEI-HFWDWSRREPFAVVK 175
             +R+W L   S  +  T   +A+ SLAF      +L +  ++I   WD    +    V 
Sbjct: 175 AAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVP 234

Query: 176 TASEMERVRLVRFDPL--------GHYLLTA 198
               +E   L+  +P+        G Y LTA
Sbjct: 235 VFESVEAAVLLPEEPVSQLGVKSPGLYFLTA 265



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 13/189 (6%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           +A +P+  LLA+   +    +  +   + +    GHRR  WCV F P +  ++A+   DG
Sbjct: 485 VAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP-MDQVLATASADG 543

Query: 119 EVRIWDLHGGS-ESWFTDSNNAIASLAF-HPTAQLLLIATANEIHFWDWSRREPFAVVKT 176
            +++W L   S    F   + ++  +AF     QLL   +   +  W     E   V   
Sbjct: 544 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE--CVRTL 601

Query: 177 ASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRR 236
            +  ++V  +    L  + LT          D    +  D TE     ++A  + Q VR+
Sbjct: 602 DAHEDKVWGLHCSRLDDHALTG-------ASDSRVILWKDVTEAEQAEEQARQEEQVVRQ 654

Query: 237 TPLLHNFLH 245
              L N LH
Sbjct: 655 QE-LDNLLH 662


>gi|5174447 guanine nucleotide binding protein (G protein), beta
           polypeptide 2-like 1 [Homo sapiens]
          Length = 317

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 61  FSPDRT--LLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDG 118
           FSP+ +  ++ S   +  + +  +   K   + IGH      VT  P  S L ASG  DG
Sbjct: 156 FSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGS-LCASGGKDG 214

Query: 119 EVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWD 164
           +  +WDL+ G   +  D  + I +L F P    L  AT   I  WD
Sbjct: 215 QAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWD 260


>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
          Length = 498

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 22/56 (39%), Positives = 33/56 (58%)

Query: 68  LASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIW 123
           +AS   +H +YI   ++   +  L GH RT  CV+++P I  ++AS   DG VRIW
Sbjct: 423 IASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 478


>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
          Length = 514

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 22/56 (39%), Positives = 33/56 (58%)

Query: 68  LASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIW 123
           +AS   +H +YI   ++   +  L GH RT  CV+++P I  ++AS   DG VRIW
Sbjct: 439 IASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 494


>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
          Length = 770

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 1/109 (0%)

Query: 46  RVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHP 105
           + EL  S  + + LA SPD  +  S   + NI + ++     V    GH     C+    
Sbjct: 567 KAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISN 626

Query: 106 TISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLI 154
             + L   G LD  VR WDL  G +    D  + I SL + PT + L +
Sbjct: 627 DGTKLWTGG-LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAV 674


>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
          Length = 526

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 59  LAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCV--------TFHPTISGL 110
           + + P   LLAS   +  + I  +K   C+H L  H +  + +        T +P  + +
Sbjct: 367 IKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIM 426

Query: 111 IASGCLDGEVRIWDLHGG-SESWFTDSNNAIASLAFHPTAQLLLIATANE-IHFWD 164
           +AS   D  VR+WD+  G      T     + S+AF P  + L   + ++ +H W+
Sbjct: 427 LASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 482



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 67  LLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLH 126
           +LAS   +  + + +++ G C H+L  H+   + V F P     +ASG  D  V IW+  
Sbjct: 426 MLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD-GKYLASGSFDKCVHIWNTQ 484

Query: 127 GGS 129
            G+
Sbjct: 485 SGN 487


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,157,804
Number of Sequences: 37866
Number of extensions: 2604829
Number of successful extensions: 11629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 360
Number of HSP's that attempted gapping in prelim test: 10329
Number of HSP's gapped (non-prelim): 1561
length of query: 1208
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1094
effective length of database: 13,930,794
effective search space: 15240288636
effective search space used: 15240288636
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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